skysight-inc/HackerNews huggingface dataset:
Anabolic steroids must be administered very carefully because they are part of a neuroendocrine feedback system.

https://en.wikipedia.org/wiki/Hypothalamic%E2%80%93pituitary...

The hypothalamus releases GnRH which tells the hypophysis to stimulate the testicles. The hypophysis releases LH which tells the testicles to release testosterone.

If there's too much testosterone, the GnRH release of the hypothalamus is inhibited. If there's too little, it is stimulated. Through this mechanism, testosterone levels are regulated.

Introducing exogenous testosterone can seriously screw with this system. The extra testosterone causes negative feedback on GnRH and LH, decreasing or stopping natural testosterone production: hypogonadism.

Physical therapy does not have these risks and is effective at recovering functionality. Perhaps a specialist would use anabolic steroids in case physical therapy alone isn't enough.
How do you weigh that against the long tail of a COVID infection having long term effects? We already have evidence of that, and zero evidence of that with the vaccine.
Erm, alert() is being deprecated? Don't like half the "JavaScript for beginners" books use alert() for the first few "Hello World"-type programs?
Restrictions being placed on unvaccinated individuals with natural immunity is based on the premise that it's not as effective or long-lasting as the vaccine.

That might not be an excuse to not get vaccinated, but it's absolutely a reason that individuals with natural immunity should not be treated any worse or differently than vaccinated individuals.

Regardless of whether vaccination improves on extant natural immunity.

And based on what we know about sars-1 and mers, that's not necessarily a safe assumption. For cases of repeated exposure and vaccination over time, the problems with those vaccine attempts were primarily over-stimulating an immune response.
What is the relevence of WebOS?

I thought that came from Palm OS, and I wasn't aware of any link to BeOS.
One key difference is that usually the captured values in a closure can't be mutated.
That's interesting: I would have assumed academics would be less inclined to use tools like PowerPoint, but I guess I'm mistaken! It really goes to show how ubiquitous it is as a tool for thought. Do you mind if I ask what the context around those interviews was?
No, we are talking about a cabal of very few people that disproportionately mod a lot of subreddits that are drunk with imaginary power and acting like petty tyrants by coordinating massive attacks against other subreddits and now that they have been rebuffed by Reddit admins are trying to bring her depressing drama to hacker news and all other media.
We are talking about a mob. A rabid mob far more dangerous in the long term than any idiot covid conspiracy theorist
There is literally a scam based on this statistical fallacy: https://en.wikipedia.org/wiki/List_of_confidence_tricks#Balt...

In short: in a large enough population with a random distribution of outcomes, you'll eventually have one member of the population who sees "you" (who is picking results at random, but mutually exclusively to individuals) pick the correct result of a sportsgame everytime.

This is the VAERS dataset: because it records any event proximate to vaccination, eventually every event is proximate to vaccination on a long enough timeline with a large enough population. It exists because, yes, they should be looked into...but only if they're occurring at a statistically higher rate then the average rate for the population over the time after vaccination. This is, for example, how AstraZeneca's clotting risk was identified and how the Pfizer myocarditis risk was identified.
> Nothing except all of Apple's attempts to make that difficult and a bad op sec decision.

No one said it had to be easy or advisable.

> Would you say you own a adobe acrobat because you paid for it, or would you say you own a license to use it?

Any software that I run that I didn't write myself is subject to the license of the people who wrote it defined it to be. Even the MIT License places requirements on you for you to be allowed to use the software. Exceptions to these copyright protections have been made which extends to jailbreaking iOS devices, which requires modifying copyrighted code.

> Buying Apple means you own the hardware and license the software that makes that hardware be anything other than a paperweight.

All hardware is paperweight without software.
Money is less of a motivator than the preservation of a lifestyle.
> I do not see anyone who understands how evil this is ever forgiving them.

I'm not so optimistic.

How many people among Apple's users actually understand how evil this is, and among those, how many do really, actually care? People seem fine enough with Facebook's data vacuuming, why would they protest against Apple's "non-intrusive" scheme? They "don't hate children" and, of course, "have nothing to hide".

The issue, as has been brought up in one form or another in the numerous threads on the subject, is that people like their comfort (using smartphones) and there really isn't that much of a choice.

> The good news is running OSX made me lazy, and getting back into running a linux or freebsd laptop again is going to be fun.

And therein lies the rub. Many people wouldn't find doing this fun. They'd much prefer being able to watch Netflix in ultra high-def and not having to futz around with Nvidia's drivers or what have you.
> "they receive treats whenever their backpacks become empty. Then their satchels are filled up with more seeds and off they go again."

They know exactly what they are doing.

Edit: I really don't know why you are getting downvotes.
You should tell the people living in tents and cars to be grateful they're not locked in a tower.
US investors are also a real issue, even if they fill their property with tenants
"Note that if someone develops Covid or dies within two weeks of being vaccinated, CDC statistics categorize that person as unvaccinated."
This is concerning and shows how much care is taken to sweep negative outcomes under the rug.
> The surveillance technology itself is not really that novel

What's novel is that the tech reports you to the authorities. Imagine your AV reporting you to the authorities for digital piracy, it's something that RIAA could only dream of back in the day. Now it's becoming a reality.
Good luck, I wish you a positive outcome.
> And as it has now been widely reported, vaccinated can not only catch covid, they have the same viral load as unvaccinated and can infect others.

Widely reported and wildly inaccurate.

They studied patients with ‘breakthrough’ infections, i.e. where the vaccine didn’t work. And guess what they found? The vaccine didn’t work!!
Fix Your Tesla – Service Manuals Online
The point is that he exposes the entire spectrum and even leans left himself, however the original commenter only mentioned the alt-right. Clearly they're implying one side is worse and somehow going to unleash terrible things, however these claims are vague, misleading, and usually made by those who just happen to be on the other extreme.

Very few people have such trouble with his massive variety of guests, topics and politics; otherwise it wouldn't be the most popular podcast in the world.
Please don't hang out in public & around vulnerable people (kids, elderly) or those who live with them. There's only one way to be responsibly unvaccinated, and that's very cautiously.

(This whole "vaccinated people have higher viral loads of Delta in their mouths" thing makes me doubt your understanding of the science, as well.)
The mention of oxygen depletion reminds me of an interesting development I recently learned of with Bryde’s whales off the coast of Thailand, although it seems more to do with direct pollution. Apparently, there’s been so much pollution from the rivers that the water is hypoxic and fish need to swim closer to the surface of water. So these whales have adapted to that adaptation by treading water and just leaving their mouths open.

It’s just one of many visual signs that things are changing, seemingly at rapid pace, in the oceans. It’s a wonderful thing to see the whales finding such a technique and teaching it to others, but it’s scary at its core.

https://www.scientificamerican.com/podcast/episode/polluted-...

https://youtu.be/-mVG6MtH-Kc
I mean I know it's obvious but talk to a lawyer ASAP was what I needed to hear. Honestly I've just bottled my feelings about this for years and then they're pretty blinding uncorked. Lawyer is correct.
Why do people think that the universality of decay can be stopped? I would even question the assumption that it should be stopped.

On a long enough timeline, the survival rate of all APIs goes to zero. (Except Lisp, which is Eternal).
Why stop at photos you take?

Since we're doing this on device we can just turn the camera on every few minutes and ask an ai if the camera sees something interesting.

If it sees that you're in trouble it can start streaming to the authorities.

We will finally be safe.

By the way, if your phone is off or left at home we will know you're in trouble and send assistance right away.

I wish I could say /s.
Don't know about multiple hops but generally you don't need to be nsa to do this. bgp hacks can be used to divert traffic, your wlan can be monitored for TA, your adversary might already be someone on-path like your isp, employer, or law enforcement, your isp (or any upstream transit provider including ones in different countries) can be bribed to monitor and sell traffic traces sufficient for TA, etc.
...As opposed to arguments in favor of tracking, which are totally rational and novel every time?
Thanks man. Please do give us more updates on what is acceptable thought.
I would hate to be guilt of wrongthink! It would be double plus non good
unless i haven’t read deep enough into that groups thread. this seems overblown. alert, prompt, etc. isn’t being deprecated on the entire web, only in the context of cross-origin iframes.

that being said, this post definitely strikes a chord with me. instead of adding a new index of deprecated features, it think it speaks more to the fact that caniuse needs to rethink how they approach deprecated features.
Well, the good news is the majority of us are too broke to move anywhere, so the tower sounds fine to us, gotta be cheaper than the rent now.
Matrix is a protocol, not a UI. There are many Matrix clients with vastly different UIs and UX. To distil Matrix down to a 'UI' is missing the entire point of Matrix. It is like email, it will inevitably become ubiquitous. 35m users so far: https://element.io/blog/element-raises-30m-as-matrix-explode...

There's a reason that governments, militaries and healthcare systems are choosing Matrix over Discord!

I've bridged all my other messaging apps to Matrix, now I just need a single messaging app. I even get my SMS via Matrix. Can Discord do that? Nope. If it could, would you trust it? Probably not.
I still listen to JRE for free on Spotify and I have had complete strangers strike up a conversation with me about recent episodes. I love that you can listen to episodes while the app is minimized on iOS unlike Youtube.
I still don't see what's unusual about drones. What stops fighter pilots from doing the same thing?
Just a quick note, alert/prompt/etc are NOT in danger of being deprecated. Chrome is just considering not allowing them to be triggered from iFrames for security reasons.
I appreciate the surprising subtlety of your analysis.
They are not selling, they are building a monopoly.
Just noting how similar this attitude is to anti-immigrant rhetoric nationally, which is ironic coming from someone who has connections in liberal Berkeley.

Another note, "let Berkeley be like it once was" sounds a lot like "Make America Great Again."
Terrapass and others offering these low prices are based on traditional offsets rather than carbon removal.

By this I mean they typically purchase and resell carbon credits generated by theoretically reducing emissions somewhere else - a common example to this is supplying more efficient fuel stoves to African communities. A credit is generated as theoretically there are less emissions now going into the atmosphere. This however does nothing to tackle the emissions from your car which remain in the atmosphere.

Carbon removal generally refers to these new technologies that actively capture and sequester CO2. These are currently immature and expensive but the result is "net-zero", if your car emits a ton, you remove a ton.

Some links for you:

Bloomberg dug a little into the forestation based carbon offsets: https://www.youtube.com/watch?v=20xMbGkEIQI

[Disclaimer: I co-founded this] an alternative which aims to support a portfolio of carbon removals: https://carbonremoved.com
As another commenter said, only for naturalized (non-jus soli) citizens, and only under limited circumstances, such as lying during your application or bad behavior within a few years of being naturalized. You'd likely be deported to your home country.
A short list of child actors who are doing just fine:

- Jessica Alba
- Leo DiCaprio
- Ben Afleck
- Ryan Reynolds
- Selena Gomez
- Ryan Gosling
- Justin Timberlake
- Julia Stiles
- Elijah Wood
- Lacey Chabert
- Emma Watson
- Joseph Gordon-Levitt
- Neil Patrick Harris
- Natalie Portman
- Hayden Christensen
- Ethan Hawke
- Anna Paquin
- Fergie
- Kenan Thomson
- Nick Canon
- Scarlett Johansson
- Jodie Foster
- Christian Bale
The real threat here is legal, not technical. Think mandatory on-device scanning as condition of access to the hardware market.
One issue is that an FDA advisory in May 2021 discouraged doctors from antibody testing of immunity, https://noorchashm.medium.com/fdas-advisory-discouraging-ame... & https://www.fda.gov/medical-devices/safety-communications/an...

> [FDA] blocked Americans from finding out the status of their antibody immunity to SARS-CoV-2 ... prevents un-immune Americans from knowing that they are vulnerable ... exposes already immune Americans to the risk of an unnecessary or marginally beneficial vaccination ... prevents vaccinated Americans in whom the vaccine has not induced good immunity from knowing that they remain vulnerable ... discourages a vast majority of American physicians from providing the people with the necessary prescriptions to obtain COVID-19 antibody blood tests ... Every American deserves easy access to information about their personal immunity status in order to make a cogent decision to maximally protect themselves.
Am I immune? Did my vaccine work for me? Am I still immune?
It's not! Just being able to trigger alert from an iFrame that is being reconsidered.
> I think in the end we will all get infected over the coming year or three as protection from the vaccine wanes and we have repeated exposure due to multiple waves and increased social mixing, but the vaccination should significantly reduce incidence of serious illness and long COVID. After having both the vaccine and (I think unavoidable) natural infection hopefully we should have a long lasting strong immunity which will keep future waves at bay. This happened naturally with Spanish flu over 2 years, but it decimated 1-4% of the global population in the process due to not having vaccines or therapeutics.

We're already close to 2 years with SARS-CoV-2 and the experts are talking about new variants, not the end of the pandemic.

While I am vaccinated and think it's clear that the vaccines are effective at reducing the incidence of serious illness and death, my concern is that by vaccinating into a pandemic, we have created selective pressures we can't predict the consequences of.

There could also be other unintended consequences. As you noted, it seems natural infection followed by vaccination results in lasting immunity, but what if vaccination before natural infection has the effect of limiting the immune system's ability to develop broad T-cell immunity? If this turns out to be the case, all of us vaccinated people might actually be delaying the end of the worst of the pandemic.
Has anyone here used it? Or TB-500?

I have a tendon/pulley injury that doesn't seem to want to heal and I've been researching it. At least one relevant study.

There is one Dr. in my area (a gyno of all things) that has a website promoting his practice using it. So has at least a sheen of professionalism.

https://pubmed.ncbi.nlm.nih.gov/21030672/
I actually did get that too on desktop. It is a bit annoying but not enough for me to call it bloatware.
The 'average person' is not uncommonly switching to Matrix. Even non-technically savvy people are asking how to do it following Apple's PR disaster.

You clearly don't understand Matrix. Dendrite introduces a hybrid-P2P model, ergo home servers become largely irrelevant, and portable identities become a thing.

Can Discord work offline P2P via Bluetooth LE? Nope.
> and it may not be legal given consent/opt-out requirements.

It would be a remarkably narrow law that made it illegal to do something client-side but not server-side. AFAIK it's usually about what data you collect and how you use it, not precise details about how it was collected and stored along the way.
We were talking about silent things here. So there is no prior expectation for them? Silently expanding scan for every file for example would count still overstepping similar way for the most of the people. Because that is abuse, and usually there is zero tolerance. Apple has avoided marks of the abuse in the past pretty well.

But anyway, Photos spotlight, Files app or Siri are already scanning you files and getting metadata. Metadata is even stored to iCloud to be able to keep sync process working. There are excuses if you want to make them.
Sex Workers are well aware of crypto bros saying "you should be using crypto for this"

It clearly doesn't meet the needs of these customers, regardless of whether or not it's "supposed to"
So what? Do you crib at indiehackers/onlyfans/YouTube creators raking in similar amounts.
They never added those things as a standalone subject to primary school & middle school curriculum since 1978. Not even Maoism.
I have a problem getting to his point when the examples he shows at the start are so unlike what I see when I enter the same search phrases.

"COVID-19 trends in Palm Beach" didn't bring up any hotel listings. Instead I get statistics, cases, and a map of cases from the New York Times, and after that a list of ordinary links.

"the walking dead season 11" showed an ad from AMCPlus.com, which is fairly understandable since it's totally on point, followed by regular links, the first to wikipedia.

I know that what individuals see is customized to some extent, but I can't imagine what sort of search history he has that would get the results he shows.

If his examples are not typical, it seems possible his premise is flawed.
This seems like hyperbole. Would east coast like density be that bad in urban portions of California like the Bay?
Not at all. Having a larger pool of applicants, for example from a large immigrant population, can only help. If I were hiring, or selecting the best students, I would want to make my selection from the largest possible pool.
This feels like an attempt to normalize wage reduction & reduced benefits in exchange for working from home.

I call BS. No one should accept this.
I don't think they went into this as a profit-making venture. Obviously they don't want to lose money on it, but it was supposed to be something much simpler and a celebration of 20 years in business, and they wanted it to be a piece of hardware because they'd never done that before.

In the linked podcast episode, they talk about it being a clock, but they wanted something more dynamic, like a Game&Watch system that sent a new game each week, but then they realized no one plays those simple games for more than 30 minutes tops, and it eventually evolved into a full-blown portable game system.

I hope this thing is popular and profitable enough that it gets a life of its own, so that it remains in production for years to come with regular new games. Because it sounds awesome, and I want one.
Remarkable 2 is the only one I have experience with, and I recommend it highly if you are comfortable exploring the community APIs and tools. It uses a proprietary cloud platform by default, which may not appeal to folks, but you can use ssh over usb to avoid their cloud entirely. I use a script based on https://github.com/subutux/rmapy to send the tablet pdf files with one command. The reading experience is excellent and the writing surface/pen are great for marking up documents as well. It's a magnificent paper notebook replacement that you can fairly easily put pdfs on. If you need on-tablet web browsing, other apps, or state of the art epub reading, I'd look elsewhere. For getting reading material off a backlit screen as though it were an endless stack of paper with arbitrary content, it's phenomenal.
The main purpose of this project is to write a minimal implementation of Git for me to understand how Git works.

Yes, supporting it is under my plan.
> And as it has now been widely reported, vaccinated can not only catch covid, they have the same viral load as unvaccinated and can infect others.

They have the same viral load if they get infected. But the mRNA vaccines still reduce the chance of being infected by about 80% (according to [1]), which in effect reduces the chance of infecting others.

> And the vaccine is waning off in 3-6 months.

Its effectiveness goes down, but it would likely take years for it to go to zero. Regardless, that's what booster shots are for.

> There's a huge population in the world which can't even get their first dose of vaccine while here we are giving out 3rd doses.

True.

[1] https://www.medrxiv.org/content/10.1101/2021.08.18.21262237v...
As if border collies took the decision to do that by themselves.
I'm not debating that it happens. But who's paying to have these articles published and promoted? PR dept of OnlyFans is your only answer.
> If sizes were sensible then…

Sorry, but they simply don’t meet your (non-standard) definition of sensible. Both of the sets you mentioned can be interpreted as the set of even integers. This set is in bijection with itself (trivially), and thus is not considered to be strictly smaller than itself.
Of course it breaches plenty of ToS, they're third-party bridges for Matrix that are developed by people within the community. Do you really think that big corps are going to be happy about people not seeing ads? Of course not, ergo there are ToS clauses there to discourage people from doing so.

For non-programmers, there are cheap turn-key SaaS. Look at Beeper for example: https://www.beeper.com/

You also don't need to start the chat in another app, that's complete and utter bollocks, regardless of whether you use SaaS like Beeper, or your own home server.

I'll check back in with you in 5 years and we can laugh at each other: @hammy:matrix.splitanatom.com :- )
This argument is commonly thrown around, but makes no sense in practice.

The denser the place, the more efficient the infrastructure use. 50 families in a single apartment building use massively fewer pipes & power lines than 50 families in single family homes. But the tax revenue for the city can still be the same. In a denser area, those families are less likely to own or need cars, and if they do, they drive less.

On the other hand, low-density suburban neighborhoods are often so inefficient that the maintenance cost of their infrastructure is more than the tax revenue the residents bring in. (Here's a good overview of that: https://www.youtube.com/watch?v=7IsMeKl-Sv0)

It's more true to say that "we don't have the infrastructure for single family homes" than it is to say that we don't have the infrastructure for apartment buildings.
I'm more optimistic.

Regulation and necessity to survive will funnel more money and effort into this area.

Regarding the viability of solutions I don't think there will be a one-size-fits-all approach and it will actually take many removal methods combined to make a dent.