skysight-inc/HackerNews huggingface dataset:
Don't most viruses just deliver mRNA that tells the cell to make more viruseses? I thought only a few, like herpes, deliver dna. That's why it can't be cured. DNA vaccines used to be commonly used on dogs and livestock to prevent things like rabies iiuc. It wasn't until these jensson booster shots that I've seen them being given to people on a large scale. Also there's a big difference when the mRNA and DNA code is emerging organically and when it's being engineering in labs.
> NoSQL databases are maturing, for sure – we’re starting to see support for transactions (on some timeframe of consistency) and generally more stability. After years of working with “flexible” databases though, it has become clearer that rigidity up front (defining a schema) can end up meaning flexibility later on.

So funny to me that NoSQL boosters have only recently understood that designing sane schemas and knowing what order your data is inserted is important for data integrity. It's like an entire generation of highly paid software devs never learned fundamental computer science principles.
nothing to do with age. this is published by "PlanetScale is a MySQL compatible, serverless database platform powered by Vitess." -- they have vested interest in promoting the complexities of DBs.

In my view the author has absolutely zero basis to make such a claim.
Good thing southern hospitals have a lot of space for casualties right now.. .
This is what dynamic dns is for. Your isp should have you covered there, and if not there are other free ones.
Genome of a middle Holocene hunter-gatherer from Wallacea
Hey - you're seriously breaking the site guidelines here by attacking other users. Not cool, please stop.

https://news.ycombinator.com/newsguidelines.html

As for the topic - thoughtful critique is welcome but you're not really doing that. I'm a bit perplexed why this startup, of all startups, is the one that set you off, but ok - we all go on tilt sometimes. Still, please follow the site guidelines.

Edit: here's an example of what I mean by thoughtful critique: https://news.ycombinator.com/item?id=28327948. That commenter is bringing up what (I think?) is the same point you're objecting to ("do you think vendors won’t do everything to make your access more difficult or cut you off completely"), but it's a fine comment and obviously part of curious conversation, which is what HN threads are for. If you could comment more like that, we'd appreciate it. If you can't or don't want to, that's fine, but then please don't post.
In my previous job me and latency-sensitive engineering teams in general mostly went with just four core latency measurements.[ß]

- p50, to see the baseline
- p95, to see the most common latency peaks
- p99, to see what the "normal" waiting times under load were
- max, because that's what the most unfortunate customers experienced

In a normal distributed system the spread between p99 and max can be enormous, but the mental mindset of ensuring smooth customer experience, with awareness that a real person had to wait that long, is exceptionally useful. You need just one slightly slower service for the worst-case latency to skyrocket. In particular, GraphQL is exceptionally bad at this without real discipline - the minimum request latency is dictated by the SLOWEST downstream service.

To be fair, it was a real time gambling operation. And we were operating within the first Nielsen threshold.

ß: bucketing these by request route was quite useful.

EDIT: formatting
Free Book: The Science of Science
I've been following the storm via Nullschool and its forecast model (GFS).

Landfall of the eye has shifted about 40km westward, been delayed by about 6+ hours relative to the forecast 18 hours ago, and increased in intensity.

The green circle here represents where the eyewall landfall was previously forecast to occur at about noon CST. Current forecast shows landfall at Jack Stout Bay, south of Morgan City, and tracking about 40km west of New Orleans proper.

The area of landfall has been hit by several storms in the past several years, is mostly smaller settlements, and there are probably numerous already-damaged or only partially-repaired structures.

https://earth.nullschool.net/#2021/08/29/1700Z/wind/surface/...
Armed guards would increase the risk that someone is killed. According to German law, a guard would only be entitled to use its weapon in self defense, not in defense of the things to be guarded. Using a weapon is only justified when no other means is sufficient to ward off the threat to one's own or someone else's life. Shooting and killing a thief can result in a murder charge against the shooter. It would also make the job of the guards far more dangerous, when burglars are expecting armed guards and would be tempted to use violence first.
I know one shouldn't attribute to malice what can be attributed to incompetence, but in this case I think malice is where it's at. Western executives are not so dumb to think China will play nice with them. I've never met anybody whose spent more than 2 hours working with the Chinese who thinks they are remotely trustworthy. Western execs whole plan has been to pump short term numbers, cash in, and get out before the CCP pulls the rug out from under them.
The dashboards would show generally quality measure performance, often outcomes but sometimes process measures. So, things like "percent of eligible patients who have had cervical cancer screening" or "percent of hypertensive patients who have controlled blood pressure" (outcome measure), and perhaps "percent of patients missing source documentation" or "percent of patients with no appointment scheduled" (process measures). The initial tableau report would let you drill down to see which patients were non-compliant for that particular quality measure, presumably allowing them to follow-up as needed.

By the time I left, we had a newsfeed that would just tell them what needed to happen ("you have N patients who have uncontrolled hypertension with no follow-up appointment booked. Consider messaging them to book an appointment."). No rates, just that story in their feed, with a link to the list of patients that corresponds to the "N patients". That would all be thrown into an email and sent weekly, and we'd track when they opened, clicked, and what ended up happening with the individual patients.
Taiwan Semiconductor Manufacturing Company is the keystone of our entire digital economy. The US should probably diversify supply chains in ways that make an island vulnerable to Chinese takeover not the keystone of our modern way of life. Until we do that, you'd better believe America has an interest in defending Taiwan—probably more of an interest than any other single place on the globe right now.
It's financially toxic for them not to invest in the Chinese market.

Name a major American brand, and odds are you've named either someone who manufactures in China, sells to China, or more commonly, does both.

When it comes to optics or money, boards and investors will choose money.
>Kievan Rus' (Old East Slavic: Роусь, romanized: Rusĭ, or роусьскаѧ землѧ romanized: rusĭskaę zemlę, "Rus' land") or Kyivan Rus',[2][3] was a loose federation of East Slavic and Finno-Ugric peoples in Eastern and Northern Europe from the late 9th to the mid-13th century,[4][5] under the reign of the Rurik dynasty, founded by the Varangian prince Rurik.[5] The modern nations of Belarus, Russia, and Ukraine all claim Kievan Rus' as their cultural ancestors

Copied from the Wikipedia, so if anything that suggests we need to bring back the USSR and reunite all the Slavs under one flag.

роусьскаѧ землѧ literally translates to "Russian land"
Well that is a good point, it's the dog that didn't bark.
Ask HN: What would visitors from another planet read to understand humanity?
If there would be visitors with no knowledge about our society, species and behavior, what would you recommend them to read, so they understand?
We're doing that.

https://pr.tsmc.com/english/news/2033
One blind programmer has worked on the Rust compiler. Indirectly he is making a library like this possible. Should we leave him out, because he is a minority?
> astronomically low costs

=)

It seems Musk had changed the meaning of "astronomically".
Bluntly because the US can't. No one is going to say it out right, but the PRC’s military has modernized sufficiently that the US is likely incapable of defending TW anymore. Which is ultimately secondary to the goal of containing PRC that the US still could accomplish in other ways. It's simply not in US interest outside of short term semiconductor concerns that's rapidly being reshored stateside to potentially embarrass itself failing to defend TW. Worse if formal promises or commitments are made, and catastrophic if the US loses trying.

e: account throttled, last reply for this thread

@Ekaros

I think in case of war prior to TSMC productions shifting off island, the survival of those fabs would be the only point of agreement and deconfliction between the mexican standoff. The idea that US would negotiate conceding TW to PRC over fab sharing access / where US controlled supply chains ultimately determine the fabs viability is not inconcievable. The US is fucking negotiating with the Taliban over civilians. Thre are tons of US civilians AND economic interests in TW worth preserving, even if it means handing TW over to PRC, as long as said economic interest has US leash. Which TSMC supply chains are absolutely tethered to. Why would TW agree? Because they're a developed country who doesn't want to be Yemen if conflict gets seroius, it's their only short term barginning chip.
What you could do is a fast-learning process, of learning what are the different algorithm families, and when they're relevant, this alone is already super valuable even if you don't know how to use those techniques yet
Oh cool, you want to use different definitions. No matter. Point remains: the floating point representation of 1/4 is not approximate. Similarly, the closest floating point value to 1/10 also precisely defines some value: it's exactly 0.1000000000000000055511151231257827021181583404541015625.

Now whether that's accurate to you depends upon your application. But the numbers don't care.
Do you define locks as things that guarantee data integrity? Is not offering concurrency at all locking? Is your point that optimistic is locking or that it bears some surface similarities to locking? I accept that surface similarities exist. But that doesn’t really help anyone understand the difference. Nobody is struggling to see that these two solutions are applicable to some of the same problems.

Locks don’t directly guarantee data integrity. They guarantee mutual exclusion around a critical section or mutable access to data they logically contain. Mutual exclusion is a coarse-grained way to get actually serialized execution of concurrent accesses. That gives you the data integrity. Mutual exclusion also gives you all the problems when you send an acquired lock over a network. It also explains why parallelism on the guarded section/data is 1. This can be blocky in a read heavy environment, because each read blocks all the others. Two transactions can get into deadlock by acquiring in a particular order. These are characteristics of all locks.

Optimistic locking (also known as optimistic concurrency control, because it’s not locking) does not provide mutual exclusion, in any way, shape, or form. You cannot acquire any kind of lock with it. There aren’t any. A lock has a pair of operations, one to begin mutual exclusion and one to end it, but OCC doesn’t have either. Because it’s not a lock. It therefore does not suffer from network partitions between the lock and the client, does not shove all readers through a parallelism=1 bottleneck, you do not have to worry about deadlock prevention or avoidance. Those problems simply do not exist for OCC. It is literally lock-free. It almost couldn’t be ANY further from being a lock. You don’t have to accept that retries being mandatory in the API makes it not a lock. You just have to observe that it isn’t a lock.

Some things are locks, some things aren’t. I think we should avoid calling things that aren’t locks locks, because it’s confusing enough as it is. Frankly, I think if people hadn’t been calling OCC “optimistic locking” then this blog post would have been easier to write. Similarly, as I illustrated above, calling it “lock-free” helps people understand OCC’s advantages and challenges in the same terms we use to talk about lock-free algorithms on a multi-core CPU. It gives you the intuition that every client side call should be a loop. It gives you the intuition that overflow ≈ the ABA problem. All of these bits of understanding flow from calling things what they are.
They probably asked 50 people and show only the most interesting ones. Still funny.
Because I know personal ads were made possible by obtaining private information about me, whereas non-personalized ads likely weren’t. I’m not going to interact with either of them so I prefer the ones without privacy cost.
> Destroying a US carrier group means the death of tens of thousand of American troops and the destruction of tens of billions of dollars of materiel

I agree. It wouldn't be a small escalation. But it still wouldn't merit a strategic nuclear counterstrike.

Point is, there is a lot of room for escalation before we go into strategic nuclear war. Or even physically damage on either side's mainland.
Brussels battles old prejudices as it frees unloved river from its vault
Show HN: Book Roulette – see interesting books when you open a Chrome tab
I know it's a bit much to single out Apple on this, I have older hardware from other manufacturers that will never run Windows 10 and Windows 11 won't run on some current Microsoft hardware. But Apple don't have that much hardware to support, it's not like they have thousands of variations of mac minis. I find it frustrating that the decision to make this machine unuseable was a reminder that a company like Apple is really in charge, not the owner of the device.

Its like the razor companies always changing the cartridge formats so your razor handle becomes useless and you're forced to buy a new one or go back to safety razors. Its the waste that bothers me most.

I am back to safety razors for shaving and Linux is the closest equivalent.
Dream Job: Meet the People Who Staff Argentina’s Highest Observatory
Another, less rosy take: https://world.hey.com/dhh/apple-s-new-settlement-is-a-corrup...
Just to make sure, the bit about "remarkable calm and informed", was not mean ironically.
They're creepy as fuck. Same reason someone might not like being followed around everywhere, even if the person following them just writes down stuff about them but never does anything else. Spying ads are like that, but worse: it's like that person also occasionally runs in front of you to slap an ad-bearing sticker on some surface you're about to encounter, based on stuff they've written down.

Spyvertising is that, but at an industrial scale. If one's creepy and ought to warrant intervention by law enforcement, the other's much, much worse.
I live in a part of town affected by one of the pump outages. In any other city in the country this would be shocking and whatnot. Here it’s an opportunity to lampoon the local government because that’s all we have.
What about the "check engine" light or the "low oil" light? Both are debugging indicators about the health of your engine.

But snark aside, I do agree with your about the intent of a dashboard. I've always told people dashboards are there to give you historical and real-time info about the performance and rates of your systems. It doesn't show you exactly what's wrong, but it is very helpful in showing where to start looking.
There’s so many vanity metrics in business related data science that I suspect when the visualization gets blamed instead of what is being visualized.
You know in Authy (Google Authenticator is similar here?) when there's only 10 seconds or so left to type in the current code so you wait for the next one to appear? Could it not show the next code instead if there wasn't much time left and the app you're authenticating with could accept the current or next code? Feels like an obvious annoyance that's fixable.
Be the Emperor’s Kid
Book Roulette is a Chrome Extension that shows you a new, hopefully interesting, book each time you open a tab. It also shows you a few recent articles from around the web that mention the book.

There are a few other Chrome extensions out there that do this. 100 Million Books, for instance, is very nice. The reason I don't care for it is the books are completely random, and often super esoteric.

Book Roulette uses the backed from the book recommendation engine The Hawaii Project which scans over a thousand book review websites to see what people are talking about. Book Roulette pulls from the more popular books on a given day so the results are likely to be topical some way.

Enjoy! (It's free, but the Amazon and Bookshop links are wired to my affiliate account so if you buy I do get a commission).
Its very common for men to play girl avatars and for women to play men avatars in online game. Very rarely have I ever met anyone that was actually pretending to be that character.
White House More Than Doubles Its Inflation Forecast in New Update
I did not intend to say that but I would say that

...adding, more exactingly, that php/laravel is _so_ popular and they are each so accessible that they should really be your first choice -- unless you have some compelling reason to go in a different direction. If you get to the point where you have funding, then your hired techie can worry about how to grow the tech. Adding, starting with one stack does not confine you to that stack. For instance, your web stuff can be in php/laravel, and your back end processing jobs/crons/queues/scheduled tasks can be in python, or hosted as js/node lambdas at aws, etc. Would be common. God knows what tech you will use to build your mobile apps -- about the only thing anyone could reasonably promise you there is that it _will_ be a disaster and it _will_ be the wrong choice no matter what choice you make there. So just start talking to people, documenting, probing, dealmaking, marketing, distributing, and building. Imo.

I misspelled Balsamiq too

Laravel is not perfect

For instance, their new version 8 massively complicated the entire ecosystem in myriad ways

But its still probably the safest best option

A big part of my decision would be if there is an existing saas/boilerplate/plumbing 'framework' available for the chosen platform

I'm confident in two or more

A couple/few related to php/laravel, and saaspegasus for python/django

I think there are certain truisms about this part of your journey

(Admitting I have zero basis to be listened to other than years of learning how not to do things, years of reading and listening to startup articles/pods, etc.)

Make a decision and move

There is no right answer

There is hardly a wrong answer

Do all the things that startup people say they will but still do not -- like stick to the M in MVP and not chase features without talking to paying users, don't write the native apps unless/until you truly need them (they are so much gd work), etc.
https://www.worldometers.info/coronavirus/usa/louisiana/

https://www.nytimes.com/interactive/2021/us/louisiana-covid-...

2,600 hospitalisations presently.
I live in Louisiana, and attended Tulane for a while. Some streets around Tulane floods after a few hours of rain. I hope that every who lives in NOLA or high risk areas just goes ahead and leaves for right now. Some people tried to stay and party during Katrina. Hopefully folks don't make the same mistake twice...
It absolutely does.

https://www.theregister.com/2014/09/13/apple_to_get_15_cents...
Recognizing a need for non-disruptive extensability is yet another benefit of decades' hindsight. Invariably, though, dimensions not so well allowed for will sprout necessary extensions like thistles that need to be lived with indefinitely.

Of much greater value than smugness for bullets dodged is humility in recognition that not all will be (or, indeed, have been).
It's not just a lack of domestic skilled workers. I'm not really sure there is much of a lack. It's just that US labor is so much more expensive compared to earning power. US workers can't pay other US workers.

Getting parts CNCed in China may be 10x less than the cost in the US, and materials are a tenth the cost as well (in small qty) as they haven't been transported yet. You can get roughly the same throughput in the US if you want to pay for it, but it will be vastly more expensive.
The opposite view was a mainstream media narrative last year, in that a suggestion as such was very widely reported:

'The rapid waning of antibodies did not necessarily have implications for the efficacy of vaccine candidates currently in clinical trials, Imperial’s [Wendy] Barclay said.'

“A good vaccine may well be better than natural immunity,” she said.

https://www.reuters.com/article/uk-health-coronavirus-britai...

https://www.google.com/search?q=“A+good+vaccine+may+well+be+...
Western executives only care about getting paid, they don't need to care about geopolitics because they will have already offloaded their responsibilities before it matters.
Personally I don't see that as getting people hooked, more so incentivizing online ordering.

My theory is Dominos has figured out that online orders are much more efficient to take than phone orders. As such they are doing everything they can to nudge people to order online. So no I don't think it's to get people hooked on Domino's pizza because of a roulette you can play when you order, I think it's a "nudge" to get you to order online.

Regular Joe wants to order a pizza and goes to call Dominos, when he looks up the number he sees the promotion but only if he orders online. Even though Regular Joe usually orders over the phone, he orders online this time, even winning some breadsticks for his trouble. Regular Joe now orders online whenever he gets Dominos.
But, without photographs of what I think of as the Wagyu "money shot" which is a face-on picture of the "cut" surface, across the grain (I believe) which shows the marbling intensity.

If I'm buying wagyu, I want to know how the fat is distributed (size) and the ratio (amount) visually.
Buy Magic Mushroom Online