skysight-inc/HackerNews huggingface dataset:
Click-bait headline.

It doesn't say Medicare has decided to cover it yet, it's under review.

And only some privately administered Medicare plans have decided to cover it.

Some hospital systems are doubting the efficacy and refuse to administer it.

No doubt, it's a huge market. But the fact that it's a monthly infusion makes it a tough proposition.

Sovaldi was a miracle drug, priced like a Bentley. This drug is no miracle drug, but they priced it like one.
The war is a failure of imagination. You are paying millions of people to work on the War on Terror. It's nice that they're all employed, that the rich get richer etc., but can we not think of anything better to do with our time?
This is an opinion piece, not the views of the editors. They also have many opinions pieces in favor of universal healthcare and other ways to lower drug prices besides abolishing Medicare if you do some googling.
There's always DigiKey if you need something like that, which also happens to have a parametric search that's actually useful.

For your example, from the fuses search page (https://www.digikey.com/en/products/filter/fuses/139) you can apply the 2.5A, fuse type "Cartridge, Glass", mounting type "Holder" and still have a wide variety of options starting at $0.25 per fuse. No free shipping though.
A Look into TSMC’s New Cost-Saving Model That Sustains Its Global Expansion
It's about the same as some of the rougher parts of Seattle, Portland, Los Angeles (Skid Row), and San Francisco (Tenderloin). We have more camps though. It even crosses national borders--Vancouver has similar areas.
Teslas catch fire. Some catch fire while parked. Some catch fire while driving around residential neighborhoods on autopilot with nobody inside. They're garbage cars. And they're not profitable. The company's profit comes from carbon credits. They're basically a subsidy laundering system for all the other manufacturers whose cars are actually profitable.

And I notice you gave me a 6,000-word rant in response to my post, yet you dropped that whole Bitcoin thing as if I hadn't even said it.
> it’s just silly to confine quasi-generics to those 2 places

Why is it silly?
> The big problem is that Carmack is an elite software engineer, and he's not at that same tier in rocketry/aerospace despite being good at it. Elite vs good. Which is to say, he'd have to take a back seat at SpaceX (which is running at full speed; Carmack would have to try to get back up to speed in aerospace just to contribute, difficult by itself). His ability to contribute beyond that of other industry specific talent is very questionable, and there are far better people - at rocketry/aerospace - working there than him.

According to the book 'Liftoff' about the genesis of SpaceX. This does not accurately reflect how they hire. Domain knowledge and skill is part of the equation, especially for the leadership team. But they'll also pick up anyone with a proven ability of solving difficult engineering problems even from completely different disciplines.

SpaceX is doing things that haven't been done before anywhere, thus the domain experience can only take you so far...
Sadly i don't have a link, but i read somewhere about a project written in C# by 5 devs in 7 years. Same project gets rewritten F# by 3 devs without prior experience with it in 2 years. Yes it is easier to rewrite than build from scratch but still pretty impressive IMHO.
This is exactly the problem/solution we're working on at https://www.sharehold.com :)

You're quite right that it is about striking that balance. We do it by keeping the app focused on recovery codes. From there, users can optionally assemble their own personal recovery team of trusted contacts.

Either way, users get the same universal account recovery experience for every one of their accounts on every service.
I have three competing reactions to this news.

The first is something much more extreme than "yikes!"

The second is that this news -- as other commenters have noted -- means that there will be plenty of startup opportunities related to climate change. We are already seeing the initial phases of revolutions in food, power, and transportation technologies. Just today I discovered a startup building a radically more efficient small airplane. [https://www.ottoaviation.com] The 700+ years number will likely fall, and the question is by how much.

But the technological solutions will only get us so far, which brings me to the third thing:

35 generations seems daunting. Especially because urgent problems usually go hand in hand with fixes that get applied quickly. Climate change however is an urgent problem with long-term implications and long-term solutions. At the same time, the culture(s) of Aboriginal Australian and Torres Straight Islander people the oldest continuous cultures are estimated to be ~ 200 - 250 generations old. In other words, though 35 generations is formidable, it is not unheard of -- certain spas and hotels in Japan have been operating for longer than that. And perhaps we should somehow set a target for ten generations, and see how much progress we can make in that time.
> though given how fast multipliers are these days using a prime modulus

They are really fast on a single thread, but at least on Xeons I use the mul and modulo seems to have a weak spot with thread parallelism though.

To fix a set of threading scaling issue with LIKE "%pattern%" SQL queries (something like TPC-H Query13), I spent a week digging through the algorithms which work better when all the threads are doing the same thing.

I narrowed down on BoyerMooreHorspool[1] as the algorithm which doesn't seem to be hit by other threads running the same algorithm (of course, everything utf-8 matching turns unicode char patterns into exact byte lookups).

[1] - https://github.com/apache/hive/blob/master/storage-api/src/j...
I understand the response but I'm wondering why you don't have an adblocker. even on mobile on ios they exist.
As a freelancer, I use this technique to handle using my various client email addresses automatically based on directory structure. My old method involved unsetting my user info and an alias to set it on a per-repository basis, but this technique (which I only learned about a few months ago!) is clearly superior.
The American healthcare system is exceptionally bad when you compare it against the United States' relative wealth, for sure; the rest of the world hasn't solved healthcare, though.

Even if you zoom in on the few countries most people are talking about when they say "the rest of the world," there's still a tons of issues present, a lot of which are directly a result of the system that they chose to utilize. This is an issue with a lot of nuance and I wish people wouldn't make such reductive statements like this.
Ask HN: Profitable SaaS idea for a side-project?
Hi
I am 23M - Developer - in my first job.
I want to build a SaaS product as a side project which is most likely to succeed.
Looking for some extra income.

In every blog/article,they say "execution matters.idea doesn't".Is there an idea which a single person can implement well to become profitable?
There has to be some kind of standard SaaS idea which anyone can execute ( I am not saying it has to be easy) and make some money right?
I don't want to build anything novel.I just want to build the "lemonade stand" (Easy to start.Low but guaranteed profit) of SaaS world.
I don't want to make so much money (1K is great to have but any profit is fine with me)

From what I have read, common products are: Scraping, Analytics,CRM,etc...

Can you suggest me some?
Are you sure Medicare negotiating drug price through Part D?

I know the bill has been out there forever, but it's far from being enacted.

https://www.congress.gov/bill/117th-congress/house-bill/3
Two more books to read: Dawn Powell's fictional portrayal, and a biography of Clare Booth Luce! Thanks!
I almost died laughing at your comment. You have to understand the ethnic divisions that exist in the region before arriving at opinions. Taliban (Pashtuns) don't give a damn about "others" such as Tajiks, Uzbeks, Hazaras (in Afghanistan - read about how they slaughtered Hazaras around Bamiyan during 1996-1999 when they were in power). Do you seriously think they bother about Uighurs? Even if they do bother, China is unfortunately not stupid - they are capable of making deals with anyone if it benefits them. China also doesn't care about democracy, nation-building, and other impossible to attain goals in Afghanistan. You (and I) may dislike the authoritarian policies of CCP, but they know how to deal with religious authoritarians.
> If you're okay with Rt > 1 until hospitals are close to overwhelmed, then it means you were okay with allowing a doubling rate for a dangerous disease.... If you're destined to put mitigation measures in place eventually, why not just do them sooner and save a lot of suffering?

correct, it makes sense because now people have a choice about whether the prevalence of the disease will land them in the hospital. the mere prevalence is not the issue.

the subset of people that don't have a choice had the same issue before COVID existed, aka: the same distribution of immunocompromised people always existed.

this makes the calculus simply that it is back to business as usual, until ICU capacity is nearing full, that is. Since ICU capacity isn't only due to COVID cases, but due to all emergencies and injuries, then society as a whole needs to slow down to reduce the likelihood of emergency incidents, while also expanding ICU capacity to avoid future disruptions. The core of my supposition is that developed nations are not developed if emergency services are unavailable, and that governing system can prioritize reacting to that.
Tasmanian here.

It’s only platypuses if you see more than one at a time, and that’s pretty much never gonna happen ;)
It isn't easy, and if other employers found out you sued your employer they might blacklist you.

You only get 1/3rd of your annual income, and the lawyer gets 2/3rd of the income for legal fees.

Plus a good lawyer can delay the case and drive up fees and court time to the point that it is not worth it anymore.

Maybe I should have sued, but I was scared of a backlash.

I didn't ask to have IBS, I developed it from all of the work stress. Sometimes it feels like I am passing glass, and the pain makes it last longer in the bathroom.
"anybody" = an office worker that has spent his life behind a desk. We are talking about farmers and craftsmen that has marched on foot for years with their gear. And now days we know that even our fastest runners train 80% of theri weekely training in a low steady state traingins, the kind of conditioning that increases the heart size, lowers the resting pulse and improves your ability to work after rest.
This is what it looks like when you're doing everything in your power to avoid ideas such as public healthcare and good education. I guess someone would say "well, at least it's not socialism!"

[edit]
The downvotes on this validates the last sentence.
Someone who was registering domains in 1998 might be in a position now where $3 million dollars is inconsequential.
Many such cases
I'm in the highly skilled category myself, and half the people I interact with have been there at one point or another. From what I have seen, the kind of person who is willing to relocate to a new country for a job opportunity is likely to do so again, should a better opportunity arise. Many people I know have worked for a few years in the US, but most of them have left for better opportunities elsewhere. And once they grow older, the "better opportunities" are more likely to involve living closer to friends and family or a good environment for raising kids than higher salaries.

The immigrant/emigrant question is a matter of perspective. An immigrant to one country is an emigrant from another.

H-1B is a dual-purpose non-immigrant visa. When you have obtained/extended your H-1B status and are applying for the entry visa required for international travel, you are required to provide a permanent address outside the US. Once you enter the country, the immigration officials really don't like it if you claim you are living in the US. And because H-1B workers are not US residents from immigration perspective, most of them are currently banned from entering the country if they have visited places like the UK, Schengen area, or India in the past two weeks.
> So what is the signal in such conspiracy theories as the Earth is flat

Psyops, honestly.

Easy to push that theory enough it can be pointed to as the "mAnY cOnSpIraCy theorists believe this" citation.

P.S. The "signal" is that everyday person society often feels like it's being kept from the whole truth, to its detriment — to the point that either the CIA or FSB has convinced swathes of people the fucking Earth is flat with (often disappointing quality!) meme magic.

P.P.S. People//kids are really sex trafficked. Some of them end up being victimized by the elite (sole of whom are pretty weird!). You should know your post really conflates wildly different things!
There is nothing with business protecting their interests with lobbysts or without.

Only people who you could blame are lawmakers. They are the people with real power and your interest representatives.
Especially since PNW (mostly?) Doesn't make their own products - they put their brand on a bunch of generic products that get sold by various different brands, and act as a distributor and marketer.

If people want to buy on Amazon for less, somebody else can buy parts from the same OEMs and sell them on Amazon.
1. New Zealand isn't "an island", there's two, one is slightly bigger and has less people.

2. Is your implication that the UK is so close to the mainland that the covid numbers are high due to people coming over in rafts? In that case the UK should have lower covid numbers because it has a much larger navy covering a the english channel, irish sea, and the north sea. Where as NZ has to cover the entire south pacific.
As long as Apple continues to innovate, it should get easier for them.

The second coming of Steve Jobs did a lot of innovation that saved Apple, I am certain Tim Cook can do the same things.
I hear this argument all the time but are there any drugs that are only profitable due to the price gouging going on in the US?

Because it seems to me that the price difference is so large, sometimes by a factor of 10 or more, that it doesn’t seem worth it to bother going through the approval process in any other country and yet pharmaceutical companies do so. So the NPV must be positive even when the price is lower.

I also think if there were drugs that only exist because of high US drug prices that we would hear about them. Proponents of the exorbitant prices would be yelling from the rooftops about some specific miracle compound that was only possible to develop because of their tireless work at finding new and exiting ways to price gouge.

Instead all I hear are these hand wavy arguments about research costs and whatnot. Where’s the beef?
As long as those issues don't include people going broke because of a snake bite (and they don't) I'd say they pretty much did solve it.
I doubt I'll be able to make much meaningful progress on CO2 removal during my lifetime, but I'm going to try my best.

My hope is that on my deathbed, Earth will at least be trending in the right direction.
Sounds about right.

The time-constants of climate are extremely long. The whole "we must change by 2030 or we all die" meme is summarily stupid in context of the REALITY of these time-constants.

How did anyone not know this? Especially if they are so serious and knowledgeable about "climate change". Well, when it's actually religion and ideology rather than science, that's usually what happens.
Did you ever stop to think why they got voted out or do you just assume you're just smarter than everyone else?
As someone who's used both I generally am not as big of a fan of OcAML where it matters - usage in most companies and projects. Sure it has some features that are nice but often they are "nice to have's", whereas the F# has things that IMO are more necessary for day to day development. Basic things like multi-threading last time I checked weren't as ideal (particularly for FP languages where this can shine); and the library ecosystem in F# basically takes in all of .NET reducing the risk of adoption substantially. At least my team will never be stuck inter-operating with some product, and can keep up with latest trends.

What's important are minimising the risk of adoption and also allow FP to show its value since that's what will make the adoption successful. I don't want my dev's to be stuck when adopting the new technology for a project because there is a library missing.

On the C# side depends on the problem space. If your working in a space where FP can help shave dev time substantially then F# is the better choice IMO. C# is not bad, but F# shines in certain domains in terms of dev time in my experience.
1M+ lines of code to identify if a number is even
Elizabeth Barrett Browning was ahead of her time
Conventional computing has no concept of positive or negative, but rather uses a signing bit to discern their polarity (for example, an 8-bit value could represent either -127-128 or 0-255). That concept of "type correctness" is lost whenever you haphazardly cast unlike values between one another (in this case ints and strings), so we're trusting the Python interpreter to magically perform this illegal, slow operation without supervision.
Good UI and workflow are the main selling points for DAWs since at the end of the day they'll all be using the same VSTs.
Doesn’t sound “aggressive” all. Sounds like an incredibly defeatist “wait” approach instead. Doomers love these articles though so I suppose that’s why this is taken at face value.m
Afghanistan is incredibly rich in resources, and they have a suitable climate for the production of opium poppy, the precursor to heroin.

"natural gas, petroleum, coal, copper, chromite, talc, barites, sulfur, lead, zinc, iron ore, salt, precious and semiprecious stones, arable land"
https://www.cia.gov/the-world-factbook/countries/afghanistan...
Visually assess your life priorities
> There is no reason not to do both

Unintended consequences.

The thing proponents of megascale geoengineering projects are the unintended consequences. Which is baffling to me considering that the entire issue that we've gotten ourselves into with the industrial revolution is about the unintended consequences of burning fuel and releasing the CO2 into the atmosphere.
Web developers get zero say in all this. I've been in the room when developers - and UX people - call out this crap. After all, regardless of the user experience, adding all the popups and analytics garbage and whatnot makes developers' jobs much harder.

And every single time, they are overruled.
They can do either, but they have to actually decide what they do. In this partivular case their was no established best practise of how to do, and the choice that was made backfired. They will alter their behaviour.
Full on proportional representation in both houses would do the trick. You get the occasional year of formation negotiations but it would solve so many problems in the US.
Before I opened this, I thought: please god let this be a giant switch statement, and lo
This particular drug is Intravenous Infusion Therapy. It's IV fluid and it takes up to 1 hour. And it's administered by nurses trained on IV, not physicians. It can be done at Infusion therapy centers.
False Polyanna-ism is far, far worse than sober rational, scientific assessment!!

Life isn't fair. Life isn't nice.

Mother Nature doesn't give a Frig about humans or you individually. We are expendable and NOT the center of the universe. See George Carlins "The Planet is Fine" because that's reality.

Innovation takes time. 20 years minimum but 90% of all "ideas" NEVER make to reality because they are poorly thought-out "hopium" rather than science or engineering.

Flying is NOTHING like this because this is primary nature rather than technology or engineering. Seriously how is that not clear?!

In terms of technology: look up "entropy" and the energy required to overcome it. CO2 in the air already is at maximal entropy so it takes ENORMOUS amounts of energy to grab at scarce CO2 molecules diluted among a see of N2/O2.

http://www.chem1.com/acad/webtext/thermeq/TE4B.html

The Gibbs energy of dilution has to be provided to reverse and extract the CO2. The C2/C1 ratio is literally 420 ppm or 420/1,000,000.

This is why the ONLY practical means is to get the CO2 BEFORE it's in the atmosphere. Whatever is already there will take a very long time (700 years apparently - but where are you REALISTICALLY going to the energy for the duration - if you say Green, you are full of shit because you are ignoring the actual supply chains for making that Green technology and whether any of that breaks even, energy-wise).

The most effective solution is plants; it will still take dozens if not hundreds of millennia.
> I wouldn't be surprised if you could get sensitive information that would be useful for spear phishing.

I know a bunch of people with common names who frequently get misdirected gmails that include car rentals, doctor appointments, hotel bookings, etc. I've only had a few (<10), alas, and they were mostly about buying art.

(Although who knows? Maybe those "misdirected" emails are themselves a sophisticated attack to get people to click on the "unsubscribe" or "this is not me" links...)
The ecocystem did start moving forward, but it will take a long time for the older pre async-await libraries to fade away and there will always be some strangeness resulting from the fact a lot of the libraries you find use a totally different API convention that you have to call via promisifying tools.
No, we need a functional government free of bribes, not a society run by money which places the value of a life at roughly $0.
The mechanism is more expensive and adds weight. Of course they don't recline. Their value proposition is very clear, and I respect that. I just don't fly with them.
All money is make belive money
Yep, looks like "getting trained by valid reasons" to me.
Ploopy: open hardware trackballs and mouse
Hold your horses.

Problems of national health systems in other countries are not "globally" visible like insane bills for Americans.

Just go and read up how many British people are nagging about NHS.
I expect that there is shitload of corruption in health care in other countries as well but I don't read or speak German or French.

In Poland I heard about case of a doctor that died from overwork, she just collapsed because she was working 3 shifts for a month or something. Don't get me started on emergency crews that are treated like dirt and hired on as B2B contractors.

Well I am not going to get a bill that will ruin me financially but I might end up with no professional health care to help me when I am in trouble because they don't get paid enough and are worked to the ground.
The whole point of using a UUID that embeds a timestamp is when you want the timestamp of the UUID to be public. Use UUIDv4 if you don’t need time, but if you do, it makes far more sense to put the timestamp in the UUID than to have a (UUID,timestamp) pair as the latter is equivalent to just having a longer UUID that embeds a timestamp.
> Someone who was registering domains in 1998 might be in a position now where $3 million dollars is inconsequential.

looks at bank account

IF ONLY. Although I did get one offer for a domain, it was extremely low and they seemed like shady people.
I think this is algomorphizing what humans do when given such a hint too much :)
This is always such a weird defense to me. It's crazy to me to think that we won't provide universal healthcare to our own citizens but some seem to think we're altruistic enough to enable socialized medicine for the rest of the first world.