skysight-inc/HackerNews huggingface dataset:
Health leaders and politicians entire job is to build and maintain trust. Mistakes like this only reinforce vaccine hesitancy. Those that are hesitant know that the science is settled - until it isn't. The only method to account for unknown unknowns is time.

It would have been entirely possible for Fauci et. al to say "The vaccine data appears to show 95%+ efficacy, but we will be waiting to lift lockdown mandates be sure". That kind of messaging shows both a respect for science and a commitment to everyone's health. However, it was an unpopular political decision, so mandates were lifted.

This isn't the first time they've changed their course after making a decision prematurely. To the vaccine hesitant, why is this FDA approval any different? There's massive political pressure to approve these vaccines.
> And nothing "better" and more practical came out ever since paradigm wise.

I think this is a pretty poor take on the problem. If that were really the case we'd all be using winforms 3.1 (or whatever the original version number was...).

Here's the "Better" that a browser does

- It's got standards and open documentation describing most behavior

- It's got incredibly robust networking code.

- It's got an insanely flexible markup language for describing both what form elements are present, but also how they're visually displayed. (Show me how to do animations in Lazarus... last I looked it was all manual) NOTE: Not only is it insanely flexible, it also is well documented and described by standards.

- It avoided the trap of being GUI first at development time, encouraging an eco-system of tools that generate and modify the text based definition of the GUI you're going to present to users

- It has good separation of concerns. My form elements can be styled completely differently by just swapping out a style sheet.

- It has good (although often underused) A11y support. For most disabilities that you can think of.

- It has first class debugging tools available, supporting a wide variety of environments.

----

That's what the browser brings. Is it heavy? Sure. Is it bloat? Not really.... depends a lot on your use case.
Worth noting, informationally, it is a goal of the Node.js project to implement web APIs. Deno is just way ahead as it doesn't have to worry about backward compat: it's a much tougher challenge for the Node.js guys, but they are working on it.
Show HN: WishAlbum, an online wish list
Yes, that is a strange thing to promote. I don’t see any benefit to Apple for that.
Not the same ammount of crap but 3DConnexion drivers play in the same league. Huge (150M+) driver, on M1 Mac it is only in beta mode for almost a year, it forgets its 'smart' scroll behaviour - that is dumb like a brick - at every switch off, but without the driver there is no click! I am serious, the driver is mandatory to use the primary button. Without it only the mouse pointer and the scroll wheel works. It is just a mouse, although a real 3 button one, only one out there as far as I know. It does not require firewall exception at least.
I didn't say it was reason for a daily meeting. If you don't find you need them, don't do them. Just agree with your team they are unnecessary. The teams I have worked with have always found it helpful to be able to adjust their plans with the whole team in situ (e.g. I need someone to help me with X; ok, I can help if someone else could do Y; cool, if Z can work with me, I think we could do Y. If we do this, we should tell A that B won't be done this week.)
So I clicked this link, literally exclaimed "what the fuck!" and closed this tab.

I guess I'm an inch closer now.
Hey everyone, I'm the developer. Thanks for the nice comments! Happy to answer any questions.
Please actually look at the change history in https://clinicaltrials.gov/ct2/history/NCT04368728

The completion date was changed multiple times since April 2020 and they clearly appended booster trials to the existing trials and pushed back the dates.

It truly is that simple.
Fair enough. OP was talking about intuitive non-blocking APIs and I just considered "intuitive".
I was using my phone and clicking the RSS button. It looks like it uses the link “ feed:https://epilys.github.io/anatomy-of-melancholy-latex/feed.rs... . I managed to fix this by removing the “feed:” prefix to the link.

Subscribed now thanks!
If it stands simply because nobody cares, can it really be said to be the will of the people?

At best, it can be said to be the will at a moment in time now passed. But then there are the other issues I mentioned: many voters do not understand the propositions, many do not turn out to vote, etc. So I would even doubt that it's a valid capture at a moment in time.
1. masses of RDD: Resume-Driven Development

2. the delusion that the way google manages 1-3% of global computing power is appropriate for your company which bursts up to < 10 servers under "high" load

2a. though you can quickly get to a place where you do need more control over migrations once your db has a nontrivial size

3. early engineers and bad engineers love complexity. Love it.

ps -- lots of these choices come down to the choices of senior people. There are good shops out there! This may resonate with you. https://mcfunley.com/choose-boring-technology
How to Give New Developers Meaningful Work
That article uses Gary Taubes as a reference.

I like Gary, but on the issue of cholesterol is more complex than he portrays.

It is absolutely the case that LDL-C is correlated with heart disease at the population level. It is absolutely the case that LDL-P is correlated with heart disease at the individual level. Beyond the correlation, there is considerable mechanism of action evidence that small particle lipoproteins are the driver of atherosclerosis.

The primary issue with statins / LDL is that they are prescribed based on LDL-C, which is not appropriate at the individual level and are thus considerably over proscribed. LDL-C only matters at the population level, not individual. When lowering LDL-C for the population, you will only see small benefits since most people get little to no benefit from the drug.

However, people with high LDL-P will absolutely see a benefit from statins. You need only look at the FH groups to see this.
If you make $150K/year, that's still ten years of pay. We can discuss how much of a multiplier is reasonable for being punitive, but it seems rather obvious that a week in jail does not reasonably cost you ten years of Silicon Valley senior engineering wages.

For anyone who is not blessed as a programmer and merely earns the average (median) of $36,0000 year, we'd be talking about 40+ years of lost wages.
I'd be really interested to hear the authors' take(s) on movim - is this under the umbrella of "modern" and are they involved?

https://movim.eu/

I love their social networking features and have periodically used their nodes but I've never managed to get family and friends on board. I suspect easier clients would be key there, but last I checked (2015, admittedly) server support for movim wasn't great.
I don't know at all about the CEO and whether he committed fraud.

But I believe at least the CTO worked hard to build and ship a phone. We were coworkers for a while as he worked on the Saygus project (he's very capable and personable), and he brought in a prototype phone at least once, showing us its features and obviously he cared and had worked on it. I remember him expressing which features were really important to him, him demoing some cool-for-the-time video conferencing software he had written that ran on it, and later on at least once, expressing his frustration that the phone had hardware issues (manufacturing flaws I think), and the Chinese manufacturer they were working with had refused to make another prototype with them fixed, until they had more money or a guaranteed contract for a large production run (or something like that). I think he was working at it for a long time.

Edit: It seems very possible that the CEO met someone with good ideas and very strong abilities, may have had some positive intentions, but spent too much too soon or got overexcited about the $ or just not enough nose-to-grindstone at the business execution level, and/or that successfully launching a phone to manufacturing is extremely hard & expensive. But again I'm not in a position to know more.
Many comments here say that that's what browser says but there is no way to distinguish UI theme from content theme preferences and it's impossible to have dark UI with light content due to browser limitation. Hence, as they say, it's a problem of a browser, not a web-site.

If it's obvious to everybody that these content preference signals from a browser lack crucial information as to distinguishing between UI and content preferences, maybe it's safer to keep standard default (usually light) and just offer and option to switch to dark theme in case a user wants and remember preferences locally till the next visit.

There is no need to force dark theme in the absence of enough information from a browser as to exact user preferences. Browser doesn't ask for anything. It just says what UI theme a user has. It's a web-site that makes a conclusion based on limited information and then decides to force dark theme on content.

Hence, my post here is to show this situation.
Powershell is slow to start up. Do you have any benchmark to show that it actually runs slower than reparsing the same data thousands of times as text?
I recently got a Xtrfy M42 mouse and it requires no additional downloadable software. Everything you need to change the DPI and RGB are physical buttons. Which was one of the main reason I chose it over other comparable mice.
Google gives personalized search results. It seems Google is aware that you frequent Hacker News. DuckDuckGo has non-personalized search results: https://archive.vn/mxh08.
The Department of Homeland Security saying "opposition to COVID measures" makes someone a "potential terror threat" is about as knee-deep in Orwellian propaganda as you can get.

NBC News: https://www.youtube.com/watch?v=sBMCXkjaMxQ&t=778s
Lately I have returned to using a gamepad with Joy2Key for browsing and productivity in Windows, something I last did in the 2000's. It's not perfect(some mouse events just don't work right through this method so I may have to try other software) but it's reminded me of what gamepads are good at relative to mice, which is - almost everything except whipping around the cursor, which isn't useful in productivity apps anyway. Precision and speed can be had by using multiple sticks and dpad, you can hold it at many angles and aren't chained to the desk, the grips have been ergonomically refined, and there's a decent selection of sticks, buttons and triggers. I wish gamepads had some wheels or dials too, but the options already there are aplenty and I am testing a few out right now.

I currently mix gamepad with a split keyboard(Freestyle 2) and a Kensington trackball as the backup mouse; having the controller in the center of the split makes it smooth to pick up and put down. And if I really needed more dedicated controls - well, why stop at one gamepad? Maybe I should try a flight stick too.
I work on some products with a variety of bootstrap versions.

Some like 2.3.x style look really nice IMO.

Style is cyclical.
Pluto looks quite sensible compared to Gnomon and Sundial - 1Gt and 10Gt bombs respectively (yes Gt not Mt):

http://blog.nuclearsecrecy.com/2012/09/12/in-search-of-a-big...

Edit: Fortunately the development of these devices didn't get too far advanced.
If you'd like to do the assessment without sharing your name and email with a stranger, the quiz appears to be a skin of https://monkeypuzzletraining.co.uk/free-downloads/MBI_self_a...

Interpreting the results is described here: https://monkeypuzzletraining.co.uk/burnout-inventory-results

I came across this last night in an excellent blogpost on burnout: https://mayakaczorowski.com/blogs/burnout
Is you're above 50, yes. 40-50, odds are about the same as yearly flu. Under 40, you're more at risk from the yearly flu.

(I'm going from memory and may be a little off on the age ranges, but covid is heavily weighted towards the elderly while influenza is not)
I lived in DK, and as shocking as it sounds, it's true. Just a nitpick: the law is not exactly against "non-white" people, but about "non-Western". African-Americans would count as Western, Russians would not. But in effect, the policy affects mainly Muslims: it was probably designed with that in mind.
It depends. For example, small planes need runways to take off and land, and if the crosswinds are over 15 kts they aren't able to operate. In this same situation, our airships would be able to take off and land because they have VTOL capability like a helicopter and can point in any direction.
Helicopter can take off and land in really high winds, up to 40 kts, but they are 4-8x more expensive to operate than planes, and have limited range.

Our test site is by a wind farm so we have a lot of experience with flying blimps in wind, and we expect our max takeoff windspeed for the full size airship to be 25-30 kts.
> They were not expected to win, but they were not expected to fold that fast.

There was no way they did not know US assessment of the capabilities. Why would you fight a war that you know you're not likely to win anyway?

Only if you genuinely believe US advisers are delusional and your side will certainly prevail.
What is this referring to? I couldn't find any mention of a ban or any other penalty; it's just a label on the post.
> > We should if that virus kills people at a high rate like COVID!

> Given the flu kills more kids than covid

Emphasis mine.
Founder of Bitcoin money laundering service admits $300M racket
Can you help me understand how “catching COVID while not wearing a mask” is meaningfully different from “catching COVID from a family member while not wearing masks” in the context of whether masks are effective in preventing the spread of COVID? Seems an irrelevant distinction to me.
Today I Feel Low
Hi team, today I feel low. Over a year ago, I decided to change job (many years working there) and, after two intents working with some other teams/companies, I realized that I do not want to work as a team lead anymore.

Although I should consider changing industry or even job/sector, I want to say that IT job recruiting sucks, tech interviews suck and, last but not least, people who deliberately use MongoDB as a relational database sucks too, and still our is the most beautiful job in the world.

With love
Ok. I'll take your anecdote at face value and shift my views slightly in that direction. I'll also note that even if some competitors do memorize algorithms & train how to write them fast without mistakes, this memorization perhaps gives them a slight edge, but it's not the core skill that separates winners from losers. A small edge, perhaps.
The Chinese have been developing it for about a decade now, I think it's the first one to go to production, not just test.
> ... as an indictment of vaccines.

Nothing here is an indictment of vaccines per se. However, it is legitimate to have concerns over a process the rules stated at the outset were thrown out, possibly for personal profit and political motivations.

Also, see https://news.ycombinator.com/item?id=28280087 for a link to an articulate consideration of a number of concerns regarding this approval.
Parachutes have not been subjected to rigorous evaluation by using randomized controlled trials.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300808/

:D
Skip straight to the Cursor tab and set acceleration to .8 and sensitivity to 1775. Tweak from there only if you feel it's necessary.
> Those could also be long term side effects of covid.

Of course, but it's a lot worse when a cure causes issues. The point of medicine is to "first, do no harm".
Yea, however this means that @ape4's point still stands:

> But, um, seems slightly kludgy to be obvious. What if the `ifconfig` format changes slightly.
In practice, reduced range hasn't been a problem in the Used Car market to date. Outside of some well known issues with especially early model Nissan Leafs, the majority of EVs that have entered the used market have not seen dramatic reductions in range in their expected lifetimes. (If anything the used market is seeing the opposite problem: batteries are generally exceeding their expected lifetimes and in part because of that EVs are staying in the hands of first owners for far longer than comparable ICE models.)

Reduced range is far more a "PR problem" than a "real problem". For the most part, people extrapolate from the problems they have with battery life in smartphones, which are constrained by size and thermal management in ways a car isn't, and assuming it is a problem where it isn't one in practice.
You can just theme modern Twitter Bootstrap to have the old 1.1.1 or 2.x aesthetics. It wouldn't take that much effort.
You are literally not allowed to work in aged care, schools or hospitals without taking a flu vaccine every year. You also can't smoke while in the wards.

It is a firable offense to not wash your hands if you work in a restaurant.

It is a mandate at most companies to take sensitivity training.

Restaurants can reject you for not wearing covered shoes and a suitable jacket.
This AI Can Spot an Art Forgery
Another excellent Haskell based live-coding tool: https://tidalcycles.org/

Even if you don't know Haskell, it is a delight to improvise electronic music with this library. It comes with its own mini-language for dealing with musical patterns and can synchronize with any instrument. Very extensible, the backend uses https://github.com/musikinformatik/SuperDirt, a SuperCollider extension for dealing with synths / samples / effects.
Thanks for taking the time. My question was about the supposed connection between the NFT and the object of art. You're arguing about what constitutes art, but that wasn't the question. In fact, the object doesn't have to be artistic at all, it can be anything. At any rate, I'm not disputing that the object is "art". I'm questioning that there's a connection between the NFT and the object.
I suppose most of it is about drug and gang crimes. Drugs are of course debatable.

Here in Berlin we have parks taken over by drug dealers and people don't feel safe. What is the solution? I don't know. Berlin's government responded by giving the drug dealers designated areas for drug dealing. I rather suspect they rely on those dealers for their personal supplies.
I've had good luck with the MX Anywhere 3. It's worked pretty much painlessly over bluetooth with two iPads and two Macs. (And I didn't install any extra software.)

https://www.logitech.com/en-us/products/mice/mx-anywhere-3.9...
Did you mean to say that previously-infected have much less resistance than the vaccinated? I would very grateful for a source on that. I tried to find out numbers on that but couldn't find apples-to-apples comparison.

I'm saying that the previously infected w/o a vaccination are more likely to get reinfected that those who were infected and then get vaccinates: about 2.34x as likely. Reinfection rates are low [0]

The risk of reinfection if not vaccinates may also be higher than the risk for an initial infection if vaccinated: Reinfection rates are about 0.31% [1] and as high as 0.7% in some populations [2] while infection rates among vaccinated are about 0.18% [3]

[0] https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm?s_cid=mm...

[1] https://jamanetwork.com/journals/jamainternalmedicine/fullar...

[2] https://medicine.missouri.edu/news/study-finds-covid-19-rein...

[3] https://www.medpagetoday.com/special-reports/exclusives/9392...
Yep, I find it unavoidable right now... but truth is, a stable working environment coupled with a support structure of friends and family is actually a cure.

Just harder to prescribe than Xanax or whatever.
> Make gas at bottom of ocean, under pressure. Bring it up to the surface (low pressure) and run it through a turbine.

That isn't what OP meant (see his reply), but if the reason you create the hydrogen at high pressure is to reduce the cost of pressurizing it more, you would not want to reduce its pressure.

But let's say you do want to -- the energy stored in the pressure, would extracting that be worth the additional energy cost of creating hydrogen at the bottom of the ocean and bringing it to the surface?

> Plug that turbine into the machine making gas at bottom of ocean. Not exactly free energy but very efficient. Harvesting the weight of the ocean to help generate hydrogen gas.
No, it's 100% NOT socially acceptable to tell a so-called "stay at home mom" that she's anything less than a hero who's the best person ever (even if she doesn't actually do very much all day). Working outside of the home is very much looked down upon as something unfortunate that one has to do.

Coming out and actually admitting that you desire to go to work rather that you have to is incredibly socially unacceptable for a woman. This sort of statement might even get CPS called on you if the wrong person overhears it.

This wasn't so much the case 15 years ago, we have turned into a society of child worshipers.
Probably don't need additional software for that use case, just a web page.
Well there are a few issues with your question.

I don't think a society can be as "advanced" as Star Trek. Societies are hard. To abuse CS terminology, they're NP-hard (or harder?). Star Trek seems to have only external threats, all internal problems are solved. The most boring problem a real society has is that of production and it is definitely NP-hard (see Hayek?). Star Trek has not only solved that at galactic scales, but has solved much hard problems than production.

Nor I don't think Star Trek is advanced in the sense that I would consider it "progress" vs. just change. I view Star Trek as the propaganda reel of (not for, of) a techo-distopia. Vulkans and that Data android fellow freak me out more than the Klingons whose society, while brutal, I can understand. I see more humanity in a Klingon because I can see a human society degenerating into the Klingons'. I don't see any humanity in Vulcans.

Btw, their technology bores me. Their tech is either impossible (warp drives). Surpassed (communicators). Or fraught with angels-dancing-on-pins philosophical questions (the "beam me up scotty" machines)

So, with the caveat that you used ST as an example and I'm definitely not a Trekkie, let me address your question:

No, I don't.

Biological systems are far more complicated than any system mankind has made. Every "cure" or therapy is really a very good whack-a-mole with hopefully lots of statistical information to back it up.

Take blood. It has hundreds, if not thousands, of components. Some are in pg/dL level of concentrations (that's 10^-12g / 100ml). See this chart [1]. How can we every really understand all the interactions among those various components?

That is not to say that I'm a bio-luddite (I am, but that's besides the point). Take penecillin. It's brutal on the body, but is one of the most important discoveries in human history. It has saved millions, if not billions, of lives. Im very grateful for penicillin, and yet, what an illustrative example! We gave too much penicillin with too much abandonment. So now, we have anti-biotic resistant bacteria. And, almost 90 years after it's first discovery we're finally starting to understand it's role in the havoc in our gut flora.

Btw, gut flora is another, fascinating, example of how complicated bio-systems are. We're evolved to depend on a symbiotic relationship with a gut flora that we've destroyed over the last 70 years of anti-biotics and cheap sugar.

So, while I think ab-initio methods (what Star Trek does) can inform and accelerate drug discovery (I worked on that briefly in my PhD), ultimately, no, I don't think we can ab-initio drugs through the whole pipeline (need-->development-->safety_evals-->approval).

[1] https://upload.wikimedia.org/wikipedia/commons/7/7c/Referenc...