skysight-inc/HackerNews huggingface dataset:
I fear there is a very common phenomenon nowadays - especially in the world of covid - where the wrong people say something for the wrong reasons, which makes right thinking people automatically dismiss it. It's a trap and we shouldn't fall into it.

You can't say "The spike protein absolutely does not cause damage". That's going too far. Speaking as someone who doesn't pay attention to whatever the conspiracy theory of the day is, I have nevertheless always wondered about the effect of of proteins in the blood whose sole purpose is to breach cell walls. Your comment motivated me to do a quick google. There are in fact many reputable papers hinting at unpredictable spike protein effects. Here's three:

SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity [0]

The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier [1]

SARS-CoV-2 spike proteins disrupt the blood-brain barrier, new research shows [2]

[0] https://www.frontiersin.org/articles/10.3389/fcvm.2021.68778...

[1] https://www.sciencedirect.com/science/article/pii/S096999612...

[2] https://www.sciencedaily.com/releases/2020/10/201029141941.h...
How so ?

Also, looks like they jumped on Twitch bandwagon very early, Twitch coming out in 2011, and PA in 2014 ?

I guess that this comes from their previous game being some crossover between DOTA, Team Fortress 2, and a (proto-)Overwatch ?
One of the things I recently learned that sounded the most "that can't possibly work well enough" is an optimization for sin(x):

If abs(x) < 0.1, "sin(x)" is approximated really well by "x".

That's it. For small x, just return x.

(Obviously, there is some error involved, but for the speedup gained, it's a very good compromise)
Wouldn’t CORDIC have done the trick faster? There’s no mention that they even considered it, even though it’s been around for half a century or so.
I agree with this commenter, and I see nothing nationalistic in their statement.
We run a processing company for second hand clothing in Poland(as well as our own shops), and while I can't comment on exports to Africa or elsewhere, that's definitely not the case for us. Primarly because we try to make use of absolutely everything we import, but also because few years back certain legislations were introduced that basically prevent companies like ours from producing large amounts of waste, with draconian fines if we do.

So basically we buy clothes from say.....charities in UK or elsewhere, import them to Poland, sort them in our own warehouse, price everything individually, sell in our own shops. Then goods which are damaged/stained/faulty are cut into pieces and sold as cleaning rags(also done in house). Then things which literally cannot be cut into rags are sold further to a company that shreds them for textile filling for car seats etc. And finally, if you have something so utterly destroyed that it's literally useless - say a pair of shoes that have been through mud and disentegrated(why would anyone "donate" these is a different matter), those have to go to the landfill. But I'd estimate that's less than 1% of our entire output.
It's telling that the subject of their mockery is a woman and not a man.
It also means, PARTYTIME.
No, I don’t think so. That’s earnings for a single medallion.

Cab companies might own hundreds if not thousands of medallions.

For example, a single private equity firm owns about 4,000 New York medallions [0].

Most medallions are owned in pools by private firms.

[0] https://www.ny1.com/nyc/all-boroughs/news/2021/04/01/private...
Huh, I wonder if my executive dysfunction in part could be Lyme disease. I was bitten 10+ years ago - had to pull it off, though it hadn't been there long as it hadn't latched on deeply yet - it did cause a small ring; I did get and take short course of antibiotics immediately after as far as I remember.

I've heard common bloodwork done is very poor at detecting it but is there a better or sure way of detecting it?
Could an HIV vaccine actually cure those already infected?
I’m not sure which cab company owners you are thinking of, but the one I know is worth in the $XXm range from a major US city. Uber has hurt his business a lot, and he’s totally unwilling to acknowledge that maybe taxicab companies offering terrible experiences has something to do with it.
I'm disappointed by the shuttering of textile industries in east Europe. It's not just the manufacturing of finished garments; the raw fabrics that used to come out of there were above and beyond what I can find today even in fancy stores. It's like fabric manufacture centralized behind the scenes until everyone has access to the same thin, cost-optimized material and just puts their brand name on it.
hey,

this reminds me of the speech Rasmus Lerdorf - the creator of PHP *) - delivered to the 25th birthday of the language ...

* https://youtu.be/wCZ5TJCBWMg

you don't have to watch the whole speech, but during the last 5 minutes he says:

"work on things that matter (to you)"

imho. don't fall for the "money-trap", life is what happens between the (un)planned progress of your career ... and happiness has no price-tag attached to it!!

just my 0.02€

*) yes, the silly little language, which powers around 50% of the web ;)
Crypto platform hit by $600M heist asks hacker to be its chief security advisor
How to Wear Wide-Brimmed Hat: 5 Stylish Tips
Technically it's a lookup table if you pre-compute them. Memoization would just be caching them as you do them.
I always wondered how come in the US you cannot watch porn before 18, or drink before 21, but you can go to war at 16.

I am not sure if this is still correct, but you could play in a porn movie but not be allowed to watch it either.
We, as patients, pass around these apocryphal stories around, but don't look at the opposite experience of doctors. Doctors constantly, and I mean multiple times per day, get patients in that tell them their symptoms are due to disease or condition or complex X. Time and again, the patient is completely wrong. No, you don't have cancer, your lymph node hurts because it is fighting off an infection, and besides if it was cancer, the node wouldn't hurt. No, you don't have lyme disease, you're sore because you started gardening again and you are 50. No, you don't have an ulcer, you're just eating too much ice cream before going to bed.

As humans, we forget about the times we were wrong, and also don't share those stories. "I went to the doctor thinking I was dying of cancer, but it turns out I'm allergic to mushrooms" is much less likely to be passed around as a story than, "No doctors would listen to me until one did and tested me and found out I have Lyme disease."
Related: If anyone is interested, I've been working on an ECS based mini-game framework in Rust [0] that runs with this idea. It has a 1200 hz simulation clock, 60 hz rendering clock, and 150 hz physics integrator (Euler). I've also posted some example mini-games that use it [1].

[0] https://github.com/Syn-Nine/mgfw

[1] https://github.com/Syn-Nine/rust-mini-games/tree/main/2d-gam...
Do you have social jet lag?
What I really want from Git, is to be able to have just a single executable for distribution, like `/bin/git` or `git.exe`. Currently Git is a mishmash of C, Shell (yes really), Python, Perl and who knows what else. I found from my own testing that you can actually make a static native build of the core with a few tweaks, but some big chunks of the project are still in other random languages.
It's what Tinder has become, predominantly. Young attractive women get more than enough attention from social media, they're not even on dating apps as they were a decade ago. I try it once in a while just to see. But the audience is abysmal. Actually easier to go out and meet someone. Which is wonderful, but there was a bright, shining time when you could just chat and meet up on Tinder or OK Cupid.
“Chronic Lyme” is a very challenging topic because it has become a mix of legitimate symptoms (those suffering post-treatment Lyme disease) but also a pseudoscience catch-all diagnosis promoted by bad alternative medicine practitioners.

Contrary to popular belief, the CDC and medical community do actually continue to research the topics of potential Lyme persistence and post-treatment Lyme symptoms. We’re discussing this under the headline about a new Lyme disease vaccine, aren’t we?

However, there is also an out of control pseudoscience/quackery community that has attached itself to Lyme as the go-to explanation for unexplained symptoms. They’re drawn to the theories of Lyme persisting in undetectable ways, which they use as an excuse to diagnose people by vague symptoms alone. There are now a number of well-known scam Lyme disease labs that claim to use proprietary techniques to identify Lyme disease that the reputable labs can’t catch. Virtually everyone who submits a sample to these scammy labs comes back with a “positive” result.

I once tested positive for Lyme using the CDC criteria from a reputable mainstream lab. The specialists I saw did not mess around with treatment as well as follow up, but they did go to great lengths to ensure I wasn’t trying to get in with a pseudoscience or self-diagnosed “chronic Lyme” case. One of them explained that she was inundated with appointment requests from people who self-diagnosed as “chronic Lyme” after reading Internet forums despite multiple negative test results and refused to believe any other explanation. The “chronic Lyme” online communities are a terrible mess of misinformation, but the actual medical community around Lyme treatment is quietly continuing to do good work. It can be difficult to separate the two from the outside due to all of the noise made by the pseudoscience quacks that have attached themselves to the topic.
Global water crisis will intensify with climate breakdown, says report
Monte Carlo simulation? Have your CI server run millions of games in fast forward, and collect as many statistics as you can. When you make a change, check that the stats that you expected to change did change, and that others stayed the same.

Wouldn't detect extremely improbable things, though, like having a spear with a super-rare effect + having armour with another super-rare effect, since those would show up so infrequently that they wouldn't skew the overall stats much.
I don't get that push to put so much logic in the frontend. Connections are getting faster and if we load only smaller amounts of data in each request we can have a really great experience without the hassle of all this complexity.
Professor! What you just said is wrong. I looked it up on the internet
While I'm aware of specific exceptions, I expect that's the norm. People who had moving out of the city on their radar screens deciding that the past year was as good a time as any to accelerate the process.

The question will be whether the usual cycle (of about the past 20 years) of an equal or larger cohort of young people move in to replace them.
Just remembered what the SDK was called - Tekkotsu. Here's a paper on it: https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.39...
Redox imbalance links Covid-19 and myalgic encephalomyelitis/chronic fatigue
Zero-K/Spring has this built-in in the lobby (for instance a big "Invite Friends" button for the Campaign missions), and since BAR/Spring uses the same lobby, I'd guess it has this feature too ?
Contribute to OpenStreetMap from Your Phone
They will easily raise more money via debt or equity financing. There is no way they just collapse into bankruptcy.

This article seems to dismiss how deep and liquid capital markets are today and easy it is to raise capital with even a sniff of cash flow..
Tangential at best, but why was the 'r' dropped from that term? Or why not call it caching? Why the weird "memo-ization"? It makes me think of a mass extinction event where everything is turned into a memo.
As far as I understand it, the language came first and in order to teach it to others the founder created a screencasting tool of sorts, which became a company in its own right: https://scrimba.com

Ironically, it seems the company focused on content to teach primarily other technologies while using Imba to build it all. It's a rather fascinating story actually, which I'm paraphrasing and probably mostly got wrong, but if you're interested you can read more on their hiring page: https://scrimba.recruitee.com

N.B.: I'm not in any way affiliated with Imba or Scrimba. The first time I heard of the technology and the company was today, through HN, so I have no skin in this game. I'm probably also mostly wrong about everything above, so you know..
This is enormously good news for mountain bikers too.
Ghosts of the Pandemic
I’d wonder though if deer use your front yard more than you? Especially in the pre dawn hours.

Even if you garden you’re probably only out there a couple times a week?

But you could be right that quantity of deer is more important.

BTW have you considered guniea fowl? Or at least something like this might help. https://www.consumerreports.org/pest-control/bait-boxes-are-...
A lot of it is just science catching up to what is observed in the real world. I agree that many practicing doctors are operating on out-of-date knowledge, so if you happen on one of those and start talking about CFS, you might not get a positive reaction. Isn't it the same as unknowingly hiring a bad contractor, though? Doesn't mean that the engineering community is not trying to find more efficient and better ways of construction. CFS is a recognized disorder by the medical community, although the causes are unkown. That is not surprising considering the complexity of the human body.

Tick-borne illnesses are talked about a lot in Europe, ever since I was a kid (~20 years ago). Can't say I have received much conflicting information in all those years.
There's a kind of dance that happens in arguments about the post office where somebody points out that the USPS is actually profitable, absent its pension obligations, and then somebody else responds that, yeah, but they actually do have those pension obligations, so you can't erase them from the profitability calculation, but then somebody else argues that, sure, but the point is that it's not critical to the functioning of a mail delivery service that they have so many pension obligations and the point is that such a service could very well be profitable, so it's a little silly to say, "the USPS can't be profitable" when what you mean is that any organization similarly saddled with historical pension obligations couldn't be profitable. You're not really saying anything interesting about mail delivery, in other words.

I feel like there's something similar happening here. It seems fairly clear that Uber's currently structured around burning a bunch of money, but...burning that money isn't critical to the functioning of a rideshare business.

People are just kind of talking past one another on this, I think.
You'd be surprised how many physicians and nurses refuse vaccination. You'll just never hear about it. AMA is one powerful beast, I wish I had a union like that.

However, sometimes fun little things like this happen that show their true colors:

"Starting in early 2003, the United States government started a program to vaccinate 500,000 volunteer health care professionals throughout the country. Recipients were healthcare workers who would be first-line responders in the event of a bioterrorist attack. Many healthcare workers refused, worried about vaccine side effects, and healthcare systems refused to participate. Fewer than 40,000 actually received the vaccine.[29]"

https://en.wikipedia.org/wiki/Smallpox_vaccine

over 90% refused.
I used to work with a man who's wife suffers from Lyme disease. It's awful to the point of being essentially life destroying. She's in terrible pain every day unless she is using strong pain killers, which make her live in a cloud essentially instead.
As with any preventative medicine it boils down to risk/benefit and (unfortunately) economics. FDA approval process should expose most of the risk/benefit equation and the manufacturer will set the price. When all of that is said and done you will have a lot more information with which to consider your question.
I'm surprised that you're not mentioning Supreme Commander (1) : ((Forged Alliance) Forever ) then ??
It's around US$350 a year in Australia [1] under the Pharmaceutical Benefits Scheme (Around US$500 without subsidies). For low-income people, it's around $40 a year. No idea how much less the Indian generics they'd be using in South Africa cost.

Unaffordable pharmaceuticals is a purely American problem and I have no idea why you guys think it's normal or put up with it.

[1] https://www.chemistwarehouse.com.au/buy/100885/tenofovir-dis...
You're right. I misread the data.
Useful economy figures, for sure. It's the average across Europe that I'd find really surprising, given how many older vehicles there will be, and not all diesels
For context, there was some discussion here on HN about parts 1 and 3 of this series:

https://news.ycombinator.com/item?id=28183062

https://news.ycombinator.com/item?id=28197876
And a booster lasts around 5 years I believe? So not as bothersome as a flu shot even.
There's no censorship. You're embarrassing yourself by misusing a word that simple.
Nobody who is trying to defend the worst polluters seems to have any actual data giving credence to the idea that the problem is mostly caused by western waste exports.
Same Day Doughnut Shop Business Cash Advance – Same Day Business Advance
I believe he was following his urge to solve hard problems by engineering a solution to them, instead of applying technology leadership. Engineering is worth its weight in gold, but not everywhere, everytime.
Altneu.μ
my blog...
Does Tornado.cash even have the ability to block transactions?
Please note that non-60Hz displays are surprisingly common (not just "gamer monitors" with 120, 240Hz etc..., but also odd refresh rates like 72, 75, 85, 90 and 100Hz)

Ideally the 'render clock' would query the display refresh rate from the operating system, but this is harder than it sounds. The next best option is to measure the frame time, and then round to the next "common" refresh rate (AFAIK that's the only way it works on the web for instance).
Regardless of OS, updating two versions at once is asking for trouble.
Yep, the bots loaded your code from these (even more) overpriced Aibo-branded pink Memory Sticks
A simple way to build collaborative web apps
You can just as easily run a firewall as a NAT, in fact most home routers support both. And, just like NAT, by default they don't allow any connections from the outside.
This is probably another symptom of differing psychologies and preferences, but “density” and “everything closer together” sounds like a description of hell.

I’ve been to NYC, SF, Seattle… all that closeness (I called it cramped and stifling) was not something I would want to experience long term.
I'd qualify that: "...we can expect them to have more informed opinions, on average, _for any random condition_, than non-doctors."

The thing I think you're missing is that the resources to do good, deep research on a condition do exist, and the sufferer has very strong motivation to do that research and become very well informed in the etiology and treatment options. The doctor, less so. They have a lot of patients and a lot of demands on their time.

Will a good doctor put in the effort, do the research, and come up with a superior treatment plan? Certainly! But not all doctors will do this.

If you use the allegory of the pig and the chicken, the sufferer is the pig, the doctor is the chicken. It is reasonable that the average pig will put in more work and be better informed about their own condition than the average chicken.
> The investor money IS the end goal.

“But you said you would never betray our customers! —Yes, because the customer is the shareholder.” – You know it’s bad when the series Silicon Valley mocks one’s business model for a joke.

> The math on WeWork etc. finding profitability never made sense.

“Don’t worry, we lose on every unit but we make it up on the quantity.”

Yes, we were in a bubble. More seriously though, Kondratief cycles are very long cycles, 50+ years, and the phase II is land grab. Economics didn’t make sense because investors are betting that they can extort customers later on.

Example: If WeWork succeeded to make building management code as difficult as construction code, they could have evicted all companies who try to maintain their own workspace (“Too bad, he didn’t know every 4th extinguisher has to be blue to be seen in case of red light event”) and WeWork would have rented companies their own workspaces. For that, you need to both dominate and modify the legal framework to prevent small actors from giving birth.
AI Writing Tools Promise Faster Manuscripts for Researchers
Not sure about that. I knew a few people working in textile, and most of if was made in Eastern Europe because the delays were shorter. They were high-end brands though.
https://metro.co.uk/2020/01/27/tinder-is-now-giving-out-blue...

Isn’t the verification they are already doing sufficient type of voluntary verification?
My experience working on B2B in a bigger company is that enterprise accounts can be extremely demanding. They want you to be engaged while closing the sale and whenever they feel like it for the entirety of the deal.

My clients were the type of folks who didn't want a link to documentation, they wanted me to turn that documentation into a powerpoint and spoon feed it to them.

If you can satisfy these folks and do engineering at the same time good on you