skysight-inc/HackerNews huggingface dataset:
An interesting mention in the article:

> There was levofloxacin, which can cause Achilles tendon rupture

Levofloxacin is a fluoroquinolone antibiotic (a generic, also under the brand name Levaquin), along with ciprofloxacin, norfloxacin, and others. Fluoroquinolones can cause a large variety of permanent and disabling systems that doctors are not well trained to recognize. They don't just attack the achilles tendon, for example, they can cause tendon ruptures anywhere in the body, as well as retinal detachments. The Achilles is more likely to go first simply because it's a more used tendon with a higher load to tendon size ratio.

They also can cause a variety of permanent neurological conditions which doctors also aren't well trained to recognize. These drugs are well documented to potentially cause permanent damage to your nervous system, yet doctors don't know about the how or why of the damage, if they are even aware of the link. In my experience, most aren't, given that the link wasn't discovered until more than 30 years after the drugs were released.

They also cause mitochondrial impairment and die-off, along with mitochondrial DNA damage.

Given all of this, how many long term chronic sufferers might have side effects related to fluoroquinolones? Many people who are affected report neuropathy, brain fog, physical impairments, and sometimes psychosis. Given that fluoroquinolones are documented to attack almost any part of human body functioning, how do you accurately link long term chronic conditions to the use of these drugs? For fluoroquinolone damage, there aren't even tests to confirm links, only the lucky few will have doctors who put together the notes from taking medical history.
RISC-V has a solution to this which seems quite elegant - the vector length is set by the program, up to some maximum, and for the final block, it is simply whatever is left:

https://gms.tf/riscv-vector.html
Alternatively, donate to political candidates, spend a few thousand dollars on events and fundraisers. Meet and greet, just to get your name out there.

If you ever face criminal troubles, you might have someone in power who you can call. And they might make a call to the DA or field office, and they may have a change of mind.
>GC can be largely pauseless for many practical purposes and a GC language can be within 2x-3x the performance of C-like languages.

To that end, it seems like only recently we've seen automatic reference counting [Obj-C, Rust, Swift] and/or compile-time garbage collection [Mercury] in a non-toy implementation. "Breakthrough" is a difficult word because it refers to discovery and impact, with the latter coming long after the former, and it's not clear if ARC is really a game-changer for any serious applications, but it seems interesting at least.
Can someone with a better understanding talk about the specifics of how/why a vaccine like this might end up not being effective against HIV (i.e. what makes HIV so good at evading our efforts)? I suspect we've been in this boat many times in the past 40 years: a promising cure is just around the corner.
I'm curious what that other demographic is? (Totally understand if you prefer not say though)
Along the same lines, FTL won't be needed if we merge with technology and live indefinitely long.

One human lifespan will be seen as a trivial amount of time to the next step of humanity.
I'm not so sure that is the case, simply for economic and social reasons. Climate change is a much more tractable and immediate problem, yet technological developments and their implementations still seem to be moving too slowly to matter at the moment.
I definitely want to believe. Then we can explore other galaxies.

But I still can't even imagine what consciousness is.

Maybe we'll create new intelligences, punt on the consciousness question, and delegate the task to them.
I think those can be used to track you even easier. Always remember that Dzhokhar Dudayev was killed with a laser guided missile fired from a Su-25 while he was using a sat phone.

https://en.m.wikipedia.org/wiki/Dzhokhar_Dudayev

I think the only safe option is E2E encrypted VoIP to a mobile phone used as a relay.
Covid-19: UK regulator approves Moderna vaccine for 12 to 17-year-olds
The "crime" might be you made a modest profit on some crypto and "forgot" to report it to the IRS.
Building out the capacity to manufacture and distribute ten billion doses of new vaccines as quickly as we can validate their safety and efficacy would also be quite the feat.

It's nice for a first-world citizen that we were getting vaccinated against a new disease 12-18 months after it was first discovered, but with a big enough supply chain we could potentially be aiming to finish a world-wide vaccination campaign in 6-12 months, before we begin running up against the limits of our current methodologies for clinical trials.
Crystal does this, too.
People Now Spend More at Amazon Than at Walmart
> We had a small chance of getting rid of covid if we had gotten nearly everyone, 90%+, vaccinated.

By small chance, you mean 0% chance, right? Variants were already spreading by the time any vaccines were available. There are also billions of people who will likely not be vaccinated within the next couple years or so.
Personally I think it's not so much about separation of concerns/technologies per se, it's that this debate boils down to a different debate under the hood: the one about folder-by-type vs folder-by-feature[0].

The gist is that folder-by-feature is generally preferrable because it requires less context switching (in the literal sense of jumping between multiple different far away folders and scanning each for the thing you're looking for)

Single file components force you to organize code in a folder-by-feature structure, to a large extent. You can use folder-by-feature structure alongside with separation of technologies, it's just not that common to see it because the tooling to support it is not quite as optimized.

[0] https://softwareengineering.stackexchange.com/questions/3385...
Show HN: CodeRemedy- we'll clean your codebase from technical debt
Today we're launching CodeRemedy, http://.coderemedy.co/ a service that focuses on improving your existing codebase by eliminating technical debt. The process is very simple- you add our developers to your repository and they will go line-by-line through your code and improve it. We have a big team of developers with almost two years of training experience in improving codebases and who keep up-to-date with the latest technologies and best practices.

Most of software development agencies run into a lot of legacy code, especially with big enterprise applications. According to a 2018 Stripe report on The Developer Coefficient, developers waste almost half of their working time (17 hours/week) on code maintenance (i.e. dealing with bad code/errors, debugging, refactoring, modifying).

Just thinking about that makes one dizzy.

Almost half of the developers’ time is spent working on code maintenance: not developing new features, improving the look and feel of the application, or making it more secure, but dealing with technical debt and bad code.

This is when we decided to make it our mission to improve the codebase of our clients. After working with them for some time, we saw the results and they were so good that we decided to change our business model and focus mainly on that- improve the "internet's code" and eliminate code debt from as many web products as we can.

The process is very simple- you pick a plan that works for you (depending on how big the codebase is and how fast you need it to be improved) and then our developers will jump right into it and start improving your code line-by-line, file by file.
We will document everything and any change will be in form of a pull-request that can be reviewed by your team.

This is a big day for us and we hope to get a lot of feedback from the community.

Help us get rid of code debt!
SerenityOS widely uses modern C++, so I'd assume there's little point in restricting yourself to old C++ when porting a library.
Looks like finding participants for a challenge trial won't be hard.
That's interesting - Speak with Distinction, which was treated like a bible of SAE when I was in school, leans on /ju/ for stressed syllables:

https://books.google.com/books?id=hM-GDwAAQBAJ&pg=PT126&lpg=...

not my area of expertise, but I had assumed from the article that SAE and GAE are equivalent, but maybe not?
Many of my friends who are from Ukraine actually prefer to work in St. Petersburg and Moscow due to better opportunities and higher pay. Granted, compared to the US Russia's economy is horrendous, but the opportunities are still greater than what is available in Ukraine, at least as perceived by 20-something aged Ukrainians.
Is that due to more effective farming methods or just due to importing more foods? I have the suspicion that this is a case of patting ourselves on the back similar to our reduction in CO2-emissions that are merely being exported to China.
I have noticed another learning dynamic and am curious to read other thoughts and experiences.

Often, I will read about something. Say designing a PCB, or to play an instrument. I will then watch a video, read, and or attempt the task just to get the lay of the land.

At that moment, if I really power through and reach a goal, the learning is useful. I can retain and recall very reasonably.

However, say I attempt and do not reach a goal. Maybe just exploring, or for lack of time. If I remain interested, I will continue to read and or listen to audio, or video or talk to people about it.

On a future attempt not made too far in the future from last visit to the subject matter, many more things seem familiar! My ability to navigate new skills and or recall rules, details is better than I would expect. Sometimes I feel as if it is actually good to do that, let just a little time pass and then I will feel like I want to do it, and maybe that want is my mind having assembled new info seeks expression of it, a use.

Usually, I am overall more effective than I was on the initial attempt despite not being hands on.
Exact opposite of Elastic.co.
So this is different than all the other Zoom is insecure things. This is related to Zoom sending data to a “hostile” state (the US) which cannot guarantee GDPR compliance and there is no waiver to allow transmission of protected data to The US.
Given that it requires sexual contact to contract, I bet we could vaccinate a small portion of high risk people and effectively eradicate the disease entirely, without ever needing to vaccinate everyone.
Doing nothing & leaving the internet insecure is in every other media & ad & host's interest, because currently it's insecure. Making privacy better is indeed to Google's benefit. Because Google has a 1st party relationship with users: users visit Google.com, Google sees where we go.

But this is not to a user's dis-advantage. Google genuinely is trying to find a good path forward. The proof to me comes in the quest for alternatives. Find anything else pro-user being suggested. Find ANYTHING. There's nothing. It's barren.

There is a huge astroturfed war going on. Google is trying to do good. It's trying to find some compromise between content-holders & users. The content-holders are stirring up a colossal storm because they want what they have, which is everything. They're winning this PR blitz. Low, cheap, pervasive attacks on Google are winning this war, & it's users who are losing.
You can teach smart (not average) 12 year olds the basic rules how to compute derivation or primitive function, but I doubt they are capable of distinguishing between, say, continuous and uniformly continuous function. Which is actually pretty important when trying to reason your way around calculus.
Phase 1 just checks to see what is the highest dose that can be given without adverse effects. It does not test the effectiveness of the vaccine.
> Climate change true believers, on the other hand, refuse to waste even one single word convincing the rest of us as to why we should all drive electric cars, stop using straws, and not run our air conditioners in the summers - things which, if they're serious, are necessary to ensure the survival of the species.

Oddly, I heard ton about those. I heard about climate change over 20 years ago and did not stopped periodically hearing about it. They haven't talked about electric cars and straws back then tho. The big topic used to be industrial pollution and opposition to those regulation is serious source of climate change skepticism.

But as of now electric cars are subject of talk quite a lot, so are consumer lifestyle changes. There was mania around straws, tho I found that one unconvincing.
I think Teams has every bug known to computers. Though, I've found GotoMeeting to work extremely well, and WebEx has been very decent but much better than Teams.
Good point about .gitattributes files being another kind that gets passed around—but that doesn't help with things the .gitattributes file can't capture, which is most things and was part of my point about why making config natively-sharable would be generally nice and also would help to make things like sparse-checkout more useful; and, crucially, LFS Just Works™ without ever having to touch those files manually.

A good built-in implementation should do exactly what LFS does, yes. But they don't. LFS does, and that's part of why it's nicer to use for its specific purpose than doing something with shallow clones and sparse checkouts and all the rest. The best way to replace LFS in git itself would be to copy its UI as completely as possible, because it's pretty good.

Having to install & enable it is a pain, which making it part of git would fix. Having to maintain separate support for it server-side, and a separate transport mechanism, is a pain, which making it part of git at least could fix if the authors wanted to (in fact, I'd think it'd be more work not to solve that problem, in implementing it, though it'd leave vendors who want the two to be significantly separate to fend for themselves)
Google and Facebook’s New Cable to Link Japan and Southeast Asia
This is quite cynical. I think the vaccines are doing pretty dang well considering they were developed in a matter of weeks following discovery of the virus, and work very robustly against not only the variants that were targeted, but also many that were not.

HIV has decades of study and literature behind it, so why not be more optimistic about the prospects for progress?
When in Doubt, Copy
We haven't even developed normal pressure room temperature superconductivity, let alone mass manufacture.

Also, why should I privilege what Chamath has to say on this subject more than any random commentator?
I live in Minnesota and am being treated for Lyme disease for the second time in 15 months. It's no joke. The first time I got Lyme, it came with a painful shingles co-infection on top of the usual symptoms.

Now the second time, I am again worried about getting sick with something else while in an immunocompromised state. The fatigue, fever, and back pain that came along this second time was worse than the first. I needed a nap after walking up the stairs.

So, I am curious how bad and prolonged the side effects were in these 59 adverse events. If only temporary, I'd consider it worth it over getting the actual disease.

The article also asks, "Why vaccinate against something that can be cured with antibiotics?" Undiagnosed Lyme becomes harder to treat the longer you wait, and the dose of antibiotics longer and more intense.

(PS: I am so very thankful for doxycycline.)
Models of human predictions can out-perform the humans those models are based on
Sources of funding (including self-funding) for Taliban – AOAV (2017)
i wouldnt call it a language, it basically asks u to install nodejs, which is the actual language itself. U do however have a custom syntax, but i find your project much more like a web framework. Personally i would add strict typing. But that's just me i guess :)
This doesn't match up with reality though. Most anarchists are in the science camp and thus wearing masks, getting vaccines and, fighting deforestation, fighting climate change, etc. I can't think of any group with less trust in authority.
The petro-dollar is a bit of a catch 22. Either we produce our own domestically and purchase with Canada (ideally using the keystone pipeline - but we know how that played out) or we throw out all of our internal production for "environmental" reasons and continue to pillage the middle east to make sure we have enough oil.

IMO, taking a bit of an environmental hit or trading with Canada is far superior to spending trillions blowing up the middle east and causing more problems than were there to begin with in an already historically unstable region.
They can't. No clinical trials. It's a hail mary.
Governments tend to be reactive and only after multiple high-profile defeats and general pressure from defenses did they get around to taking evidence security seriously in their practices, budgets, etc.

Unfortunately it's probably going to take many more multiple TB losses (resulting in failed prosecutions) for them to take this seriously with digital evidence as well.
Has she seen a neurologist? My wife has MS and your description -- minus the positive Lyme test -- reminds me of the period of unexplainable symptoms that eventually led up to seeing a neurologist and getting an MRI and lo and behold lesions on the brain and spine that explained everything
HN Hug of death
A good thing about this narrative, for all its flaws, is that, by focusing on the Forest Charter, it creates a traditional, folk, English basis for protecting the environment.

If we could make the Right go eco-trad and aspire to regrow the Shire,

and if we could make the Left embrace its chill Tibetan-prayer-flag-hippy aspect,

with everybody living in cobb houses connected by footpaths and such,

then we'd have a sustainable utopia that everyone could live with.

Ok, I know, there is no utopia. But surely we can do better than what we have now, where the Right willfully destroys the planet, and the Left turns into a self-devouring ball of tantrums.
Interesting, the "blind spots" and "alien AI" mentioned put me in mind of the disturbing ability of AI to determine race from chest X-rays ...
We are far away from such an interface and space travel takes still far too long. When the first probe reaches another galaxy mankind is probably already gone or we are back in post war dark ages.
Corellium will pay for security researchers to check Apple CSAM claims
DIY Threadripper Laptop
A bootleg laptop with a TR 1950X (and six batteries) is the heavyweight champ.
It's probably more because Google has an almost pathological aversion to maintaining anything. You don't get the cool projects, raises and promotions by doing the journeyman work of maintaining, fixing bugs, listening to users and gradually improving an app or service.
I suspect that this comment might answer your question (Godsend or Nightmare -probably both. Old Testament Godsend): https://news.ycombinator.com/item?id=28211073
Apparently you can have a hot dog and Caesar's salad with rooster
It's not about finding truth, it's about solving the practical problem that Fox controls older minds and their votes. If the key to older minds is naive emotional manipulation, then it makes sense to use the same techniques for the opposite positions. If you use different techniques, more rational ones, less manipulative ones, more honest ones, then it will fail because people just won't watch. There is clearly a demand for what Fox provides; my idea is to keep giving it to people, but neuter it's real political influence.

FWIW, this is not a happy thought. I want people to be better, to want to know and understand, to recognize when they're being manipulated, lied to - when they WANT to be lied to. But I think that's asking too much, and it's tried again and again and always fails.

It's the emotions, and it always has been. They want a bad guy, they want simple explanations, they want to feel like they have special, non-obvious insight, and they don't want to earn any of it. So give it to them.
Additionally, unless you can convince the majority in Africa to take the vaccine, partial vaccine deployment would put a evolutionary pressure on the virus to evade the vaccine and re-infect the world with a resistant strain.
They will want you to take both the vaccine and PrEP, because (surprise!) the vaccine will not be 100% effective.
Interesting blog.
That's a non-air-quotes crime. But the statute of limitations is 10 years.
People who are not making enough money to make ends meet -- and thus end up with overdraft fees or having to make use of things like instant loans or credit cards -- don't need to get paid faster. They need to get paid more.

Whether they can afford to live or not is a matter of simple arithmetic: money left = money made - expenses. Being able to tap into their underwhelming income faster to cover a mid-month bill doesn't help them in any way, it just pushes the problem around, so that come payday, they will have even less and have to repeat the same process.

This product is only less distasteful than text message money lenders because it doesn't come with exorbitant interest rates. This product isn't helping anyone. It's just capitalizing on the poor.
I don’t know what rock you are living under but everyone uses Zoom. Even Cisco sales reps use it for sales meetings and they own WebEx.
Obviously. But I doubt app authors will bother registering menus with a global API if the global menu is not a platform standard every user expects them to follow (which is how it is in the Mac world).
(Rust does not do automatic reference counting)
True but I think you might be getting downvoted because that fails to account for the time leading up to the election (and Brexit I guess) which is what a lot of the people commenting on this subject are interested in.
Dang, Webex is still that bad for you? Is it because you're using company's instances where it's more locked down and they're on older code?

I know it's not perfect, but it's pretty reliable for me (and full disclosure, I work for a different subsidiary of Cisco - but I also try to be pretty critical of it since I'm close to it)

I don't use Zoom a ton, but I've experienced what feels like a similar amount of sluggishness and AV issues as I have on Webex. At this point I know I'm a bit too close to have a useful anecdote, I'm just surprised that Webex is still put in the same group as Teams / Hangouts / GTM.

Again, not trying to sway you, just understand a bit better.
Interesting that they have a specific carve-out for scorpions. It appears there is a good reason (making "antivenin"), but why only scorpions?
This is some damning info. Not only as evidence of outright fraud, but also of incompetence in that fraud. Uniformly generating something that's obviously not uniform, not even paying attention to fonts (!), and fabricating your result by adjusting not the collected "current" data, but rather the baseline data.

Ariely's response[1] to this puts the fraud on the insurance company. He rightly notes that better data anomaly testing would have caught this, but I also wonder why the company "knew" which hypothesis to put their thumb on? And where did the impetus come from to double the number of records rather than leave N=6,744?

[1] http://datacolada.org/storage_strong/DanBlogComment_Aug_16_2...
Not to mention members of the gay community.
Out of curiosity, do you have an explanation for the root cause of all of this?
Re HS2: I am familiar with the capacity-and-speed-difference argument, but I recently found out[0] that the WCML, MML and ECML are all already four-tracked, so you already have separation of fast and slow trains. Is further separation really still worth it?

[0] I don't live in the UK, so I didn't know that yet despite being a railway nerd.
Yeah, one of the terrible things about the anti-vax movement is that it makes it hard to distinguish signal from noise when looking at objections or criticisms of any vaccine.