skysight-inc/HackerNews huggingface dataset:
Botox contains a neurotoxin produced by Clostridium botulinum. This toxin prevents the release of acetylcholine in neuromuscular junctions. Neurons release this chemical signal in order to make muscles contract. Blocking that signal also blocks muscle contraction. It's more or less the inverse of nerve agents such as sarin.

As with all toxins, the dosage makes the poison. It's deadly yet has medical applications. Can be used to treat muscle spasms, neuropathic pain... Most famous for its cosmetic applications though: it relaxes the muscles of the face, removing wrinkles. I know doctors who literally live off of this stuff.
Ugh, this old trope again.

Yes, the senate skews congress highly rural. That's the point. It was designed that way. Frankly it works just fine except when electing a president or when doing things at the federal level that should be done at the state level.

At the state level, where most of the day to day stuff that affects people's lives is legislated the urban areas in any given state run the show unless the state is very, very, rural.

Furthermore, class based distinctions are mostly separate and parallel from urban vs rural ones. Both the hick and the hoodrat know full well their elected representatives, whether they voted for or against them, are nothing like them.
Think you of the fact that a deaf person cannot hear. Then, what deafness may we not all possess? What senses do we lack that we cannot see and cannot hear another world all around us?

Frank Herbert
A more durable reference comparison: 100W is similar to a human. An adult human, not exercising heavily, but not asleep, maybe reading a book, or talking to a friend, something in that ballpark.

Also, if you aren't off-grid, you're apparently not so far from civilisation that previous utility suppliers couldn't be bothered to provide service to you. Maybe if this generation's utility suppliers got their act together you wouldn't need Starlink anyway.
My first lecture in my first class in my freshman year of college the professor taught this book. The class was mesmerized as all our minds were blown, and we all walked out thinking “College is gonna be AMAZING. We’re gonna learn so much fascinating stuff.”

While the next four years weren’t bad, they never did quite live up to the feeling of that class.
Same observation. I also smoked weed in my teens and early twenties and I remember it making some of the most banal horse shit ideas seem profound, or like I really understand how the universe clicked together. I bet hanging out with a bunch of stoners steeping in my own bullshit for another decade would make me a(n even more) pompous ass too.
I don't have the energy or inclination to push for regulation. If or when someone invents a ubiquitous communication channel that's not overrun by spam, I'll happily pay money for it. Until then, I'll be cursing at my phone and blocking numbers.
No, but we are unlikely to find causation without initially noticing a correlation.
Why are you assuming he's saying it in bad faith? How is pointing out actual facts being a contrarian?

Indeed, contrarian to what, exactly?
>I also think the effectiveness is highly questionable given the number of high profile people that have been vaccinated and still tested positive.

Sure, the vaccine appears less effective to the delta variant. But that's not a reason to avoid it.

One of the long term effects of not getting the vaccine is death. The recent stories coming out of hospitals where people are dying even though there's a vaccine available is tragic. Let's hope it doesn't happen to you.
And 38 upvotes in just an hour. Mmm.
> Besides, if our brains are designed to zoom in on certain signals, is it rational to expect technology to somehow prevent this?

Technology can mitigate it (by suppressing the signals, offsetting the effect) or exploit and exacerbate it. The former is often socially useful, but the latter is usually the path of least resistance to profits, and capitalism isn't a system whose incentives optimize for social utility.
Possibly Akamai?
Seeing a "Service Unavailable - DNS failure

The server is temporarily unable to service your request. Please try again later."

on many sites.
I don't think tattoos are injected into the muscles - they're only skin-deep!

But good on the 1%!
Library Launches Future with Folio
So you've decided to unilaterally determine my intent and tone, appoint yourself the arbiter of behavior, and inject yourself into a conversation to double down on your incorrect stance (from Wikipedia: "Due to the flexible nature of the term 'needs', there is not one universally accepted measure of what a living wage is...") and lecture me about rudeness?

I'll pass on continuing this conversation, thanks.
So far it seems to be an Akamai internal DNS look up problem. That is, it seems if they need to resolve the hostname of the origin to serve a page they front for, it fails but I haven't seen any actual DNS failures on my side or other places, just inside Akamai-served pages saying they failed to resolve with an Akamai reference code.
It varies. I grew up not writing in books, because until high school most of the books I handled were either school books, mine to use for the school year, or library books. That was a while ago. These days, I have no scruples, but I tend to write only in work that requires some concentration, mostly philosophy. I read a fair bit of history and fiction, but don't tend to write in them.
I've yet to see a single product that was improved by being a chatbot.
Unobtrusive version: https://microk8s.io/?cp=hide#cookies
My email Feb 24: "Starlink now available to order"
So I put an order in right away.
It's now July 22nd, and I haven't heard anything, despite the original email saying "mid-2021" for order shipment. So I go to check: "Starlink is currently at capacity in your area through 2021, your order might not be fulfilled until late 2022."
Despite having taken my money for deposit they never sent an email at any point to let me know this. I think that's a rather dubious customer service practice.
One of my high school friends developed severe schizophrenia in his 30s. Given hindsight it's clear to all of us that know him that some elements of it must have started all the way back at middle school. He was very into hallucinogens and doing his art, the themes of which are directly in line with his current delusions.
A bunch of sites are down. Bostonglobe.com is down. This has to be bigger
...I don't really want to hear about your religious beliefs, tbh, I've had a lifetime of it already, and I've decided you're all charlatans.

Especially if you unnecessarily revert to jargon when trying to explain your beliefs, you mention "tulku" four times, but define it zero times. This is indicative of in-group signaling.
I think application whitelisting by signature is a better fit for that use case. If for some reason you are required to allow arbitrary applications then the malware protection is probably going to cause more problems than it solves anyway.
>> In 1995, 2% of schizophrenia diagnoses in the country were associated with cannabis use disorder. In 2000, it increased to around 4%. Since 2010, that figure increased to 8%, the study found.

Worded that way, causation isn't the first thing this suggests to me. If percentage of cases associated with marijuana rise, it could also be that a larger percentage of the population is smoking and admitting to smoking marijuana regularly. If cases themselves rise, it could also be increases in the percentage of cases that actually get diagnosed, etc.

It could very well be that marijuana puts you at higher risk of schizophrenia - I certainly have an acquaintance in mind for whom recreational drug usage seems to have led them to a paranoid and narcissistic personality described here in other comments - but the connection in this article feels weak. Certainly weaker than the connection we see between marijuana law enforcement and the negative fallout of that.
The issue is that politicians are better at the art of influence -- it's literally their job. Science is hard for some people to understand, nuanced, and it changes over time. Politicians, on the other hand, know how to harness the power of a strong and definitive statement. To someone who doesn't know better, the arguments that are easier to follow and understand are more believable.
You could put a pinch of salt into your bottle with hand sanitizer and wait for about a day till the salt is dissolved. Then when disinfecting your hands, pour a little bit into any opening you see near the screen.

(Never tried that out and never will. Hand sanitizer has about 30 percent water and salt water will both short-circuit and corrode circuits.)
Shouldn’t you and your fellow voters being holding your government accountable for what it is doing with these tools rather than getting angry with vendors for selling things to your democratically elected government?
That's like people who say, "I don't have anything to hide, I've done nothing wrong." to which I reply, "Ok. Take your clothes off right now. Remove the curtains from your bedroom window and the door off of your bathroom." The look on their face is that of incredulity.

People have an expectation of privacy and need the ability to hide perfectly benign things in their lives. Most importantly, they should have the freedom to do so, even with electronic devices where they're conducting their lives in an ever increasing manner.

Shalev Hulio's argument is so bad that it actually makes me trust his company even less than I did before.
The JVM still is an abstract specification of computer hardware (instruction set, register set, memory organization). That it wasn't designed for hardware implementation is a very minor nitpick.
Just a minor copy note:

> There are a million and 1 habit and goal apps out there and I made the mistake to think that just because there are a lot of products in this space, doesn’t mean that there is a lot of businesses in that space.

I think you were thinking of two different ways to phrase that, mixed them up, and the result is that it says the opposite?

As in, either remove 'I made the mistake to think that', or 'doesn't mean that'.
If they are impressive why not show them off?
I guess I'm not sure how you would use open() that would expose a TOCTOU bug that openat () wouldn't. Can you give an example?
How do you folks deal with the following? I borrow books from the local library but can't mark or underline anything in the book to go back and refer. How do you then keep notes to retain the salient points of the book? Maintaining notes separately breaks the flow of reading. Suggestions appreciated.
I'm impressed and grateful that DeepMind released this resource, this will save a lot of compute from labs trying to replicate an entire exome for themselves. While some structures look great, there are still some misses here. Important structures like BRCA1 (a well-studied breast cancer associated protein) are just structures for the BRCT and RING domains surrounded by a low-confidence string of amino acids, likely shaped to be globular: https://alphafold.ebi.ac.uk/entry/P38398

Maybe I was wrong for expecting the impossible here, but I was excited to see this specific structure and it appears that there is still work to do. Nevertheless, kudos to Deepmind on their amazing achievement and contributions to the field!
The DuckDuckGo service isn't claiming to be a proxy for all of your online accounts, so of course logging into your email provider to check your email means they get your IP address, user agent, etc. How else would you expect this to work?
autossh just re-reestablishes your ssh connection. It doesn't tolerate packet loss very well or have local echo like mosh.

mosh does require UDP ports, though, which might be problematic with some firewalls or proxies.
You are not only building a product you have open sourced. This project was almost a community project.

You have the moral obligation to cater for the community as you didn't just buy the project but you also inherited the community.
The more money you are accused of stealing, the more delicately you are treated. Funny, that.
As is UPS.
Capabilities mode is useful, but it's very difficult to apply to programs that don't fit the model.

If you need to make network connections, you have to do that before entering capabilities mode, because there is no capability to allow it later. You can work through a proxy program, but adding that complexity doesn't seem worthwhile to me unless your program to be sandboxed is very complex.

I haven't worked with OpenBSD's pledge, but the idea of being able to end use of specific dangerous things seems more widely applicable.
> That makes starlink fine for any kind of asynchronous content like web browsing

This sounds terrible for web browsing. Last thing I want is to know is to submit a form and then have my connection drop out in the middle. Imagine being in the middle of filling out an application or opening an account or verifying your identity or something like that.
Khashoggi... or is that an intentional portmanteau?
Looks like it is broader than the brokerages[0].

Seems like a DNS / infrastructure issue.

[0] https://downdetector.com/
Starts Aug 8; Showtime
You also increase the revenue of Acme Chatbots Inc, who will use those proceeds to hire more people to sell you a better, more comprehensive package.
akamai reporting issues now https://edgedns.status.akamai.com/
Please compare the network traffic between the 2 devices.
This is updated -> https://edgedns.status.akamai.com/
https://edgedns.status.akamai.com/

We are aware of an emerging issue with the Edge DNS service.

We are actively investigating the issue. If you have questions or are experiencing impact due to this issue, please contact Akamai Technical Support. In the interest of time, we are providing you the most current information available, which is subject to changes, corrections, and updates.

Jul 22, 16:09 UTC
> The difference for you and I right now is that we don’t view the AIs as personal enough and thus don’t trust them.

I don't trust them because I know that they're reporting to their real bosses, who aren't me. If I could have a personal assistant that was completely local and under my control, I'd begin to get interested in them.
I read an article where an online knitting community was invaded by far-right trolls and it caused a massive rift.

https://www.nytimes.com/2019/06/24/style/ravelry-knitting-ba...
> The flashlight, since there is light in whatever direction it turns, would have to conclude that there is light everywhere.

I wonder how true this characterization of consciousness is. It seems to be a critique of the classic Hindu/Buddhist perspective that there is light everywhere - in fact, light is all there is.

I also wonder about how relevant this might be to the role of consciousness in quantum mechanics.

https://en.wikipedia.org/wiki/Von_Neumann%E2%80%93Wigner_int...
I think the point is that UI design isn't really art. If you're interested in both, then great! But they're about as similar as fiction and non-fiction writing.
>They're not against the government, they speak out against the concept of government itself.

Nothing in that article describes Trump or the Republican Party speaking against the "concept of government itself." That would make them anarchists, which clearly they are not. The article points out numerous pro-government positions by Trump and implies that his position on the legitimate purpose and scope of government, rather than being founded on a rigid anti-government ideological core, is entirely transactional. The same guy who supported political protests against vaccination procedures and his opponent's election was shouting "LAW AND ORDER" from Twitter and sending troops into Portland... to crack down on political protesters.

And as far as the Republicans themselves go, the party is famously pro-military, pro-police, pro hardline stances on drug enforcement and immigration, and pro Constitution. The only form of government they consistently oppose are social programs (with the exceptions of agricultural subsidies and the GI bill), spending related to arts and sciences, public education and anything else they consider "leftist" (or more simply, anything their political opponents support.)
Parent also said:

> To be explicit, making the bet to cannibalize your own market is one of the toughest any company can make. High risk, high reward.

In other words, it is considered a viable strategy, although also a risky one. The fact that it didn't pan out in this instance doesn't change that.
I'm not sure what it is, but something about the colour palette used in the examples shown feels a bit off to my untrained eyes.

Is there actually a job market for pure UI designers? I often see UI as only a small part of job description that involves other non-art-related technical skills.

It feels like the market is already saturated with people who can do UI design and a lot more (or the other way around for that matter). I am glad that the author managed to find internship as a UI designer and I'm aware that the author plans "to extend into UX", but the emphasis on UI design as a career change for "traditional" artists sounds... dangerous.

Edit: removed confusing parenthetical.
A UFO sighting shut down a major airport and drones were blamed
what's k(9)?
Akamai Edge DNS was down
Augustine was reading manuscript without spaces, punctuation, or standardized spelling (though, granted, being Latin, a pretty regular orthography.) You can read such silently, but it really assumes you're reading it aloud, and is easier to handle that way.
Yes, ban their names and pictures too.
I'm asking to ban every mass murder because part of their plan is to gain fame to recruit followers and create copycats.
I'm against death penalty but not against killing their legacy.

Hitler and Stalin are already partly banned.
I have a co-worker who I would described as mildly happy at all times and doesn't care about societal norms/ranking, but I never interpreted them to consider themselves superior to me. This doesn't jive with my understanding of mildly happy people.
I know this pain.

In my case, I spent most of my life around 18-23 years old living in my parents' working about 100% of my time on something of my own
I had a lot of negative support from friends, colleagues, and extended family as many don't see entrepreneurship with good eyes in Brazil.

The last project I worked (https://www.youtube.com/watch?v=dML0FQIUcTY, I spent 2013-2014 on it), was heading to the right direction, but then my business partner (first and last one so far) always wanted more and more.

In the end I had other opportunities (go back to college, and start a new job), and we just ditched all our efforts. Of course, we both regret it. Especially each time when we see something similar sold for a couple of millions.

Good luck to us next time!
Yes. Yes they have FDA approval.
> Imposter syndrome generally requires that you are/were in the role that makes you feel like an imposter waiting to be found out.

Not a big fan of the article either, but this doesn't strike me as accurate from my own experience. Impostor syndrome is more often, in my neck of the woods, used to refer to general lack of self-confidence. It can prevent you from applying to a job, too.
Amy Goodman yesterday on NPR was using Gil Scott Heron's "Whitey on the Moon" for the between-segments music clip. A+.
> One in five Americans believes the US government is using the COVID-19 vaccine to microchip the population

I think people should get vaccinated, but admittedly there is a profound lack of trust in institutions these days. misconceptions like this microchip theory would be 100x less likely if the government wasn’t literally surveilling your every movement and communicated word with the help of big tech

The institutions behave in a profoundly untrustworthy way for generations, then people stop trusting them. Society breaks down. It’s that simple. In 30 years this will be amazingly worse unless things change
I used to love twitter back around 2007 to early 2010's but as it became more popular it became more toxic and now Reddit is becoming the same with a lot of people spreading
nonsense or politics.

The one benefit of reddit is I can choose the subs I go on, the problem is there are still a lot of subs that are of a topic I would enjoy that end up getting toxic as well.

So i'm trying to find a balance, because reddit for example does give me a lot of my news in topics I love and it's great for finding stuff, like a good movie, book, youtube stuff etc, but then the downside is getting bigger and bigger each year.

I struggle to cut it out completely but I also struggle to find any tool that curates content in a good enough way. Everything is just noise and nonsense online with a small amount of good stuff, but very little that focuses on just giving you that.

Everything just needs clicks and attention, I want something that doesn't need that and just gives me the type of stuff I want, not on a schedule, but when there is actually something worthwhile to say.
https://downdetector.com/

Confirmed failing for me:
ups.com
steam.com
steamcommunity.com
homedepot.com
newegg.com

Still working
amazon.com
americanexpress.com
vanguard.com
Just get chiptunes.
It's like Rent-2-Own, but for software! And no ownership!
sys.getsizeof is not recursive so that's just the size of the collection itself, excluding the stuff it references (so both keys and values are additional, here the strings are literal so they're interned and part of the program constants).
Ha, how do you end up reaching for "travel websites"? Like, what is the shared technology that they use that general internet sites don't? I clicked into the comments hoping to learn something interesting about the travel industry (like maybe Airbnb and Expedia and others are all part of some conglomerate - like how many of the dating websites are actually one company).

But, yeah, general infrastructure being down and affecting all kinds of disparate (travel and non-travel) sites makes sense and is boring.

Reminds me of an interesting study where researchers gave a list of numbers with some hidden property and let people ask if other numbers have that property, to try to figure out what it was. And people tend to generate numbers that agree with their hypothesis, to try to confirm it, rather than numbers that disagree, to disprove it. Wish I could find that study.
Isn't it great that we've stopped creating incorrect hypotheses to explain phenomena we don't understand? /s

I look forward to seeing what we're completely, laughably wrong about today, if I live long enough. I hope it's one of the things I am right about --- but I'm not counting on it.
Yep, all our EdgeDNS zones as well as DSD edgekeys are just returning SERVFAILS. Many big german websites are down right now.
It's not an appeal to authority, but rather to shared taste.

It's true there's no reference manual for the equations for pleasing shapes, because however our preferences are expressed in our brain, we haven't been able to decode.

But to give one example to your question: the serifs in Computer Modern are thicker than the thin stems of letterforms. That's ugly, full stop. It's not balanced -- the proportions of thicknesses is backwards. The entire function of serifs is to taper and/or finish, never to add weight.

Or another: the loop (lower part) of the double-story lowercase "g" simply extends way too far to the right. It makes the letter feel like it's going to tilt and fall over to the left. It's not balanced, period.

So these are just two examples of terrible balance. Does that hopefully answer your question in a way that isn't an appeal to authority?

Edit: curious why I'm being downvoted for this comment, when I'm just trying to answer the parent comment with actual examples.
Granted, popular opinion on consciousness has changed since this was written, but what scientific finding has changed since that contradicts the book's ideas?
It's Remote-Desktop-as-a-Service
Postmasters in IT scandal to get up to £100k