skysight-inc/HackerNews huggingface dataset:
My first inclination would be to base maintenance cost off cost of rebuilding (optionally overridable) -- in effect, you end up with a much lower percent of total value where you're basically paying for an expensive lot, and a much higher percent of total value in depressed markets (e.g. where you can get 100-year-old 7-bedroom for ~= national median home value).
Not knowing the difference in miles and miles/gallon will get you stranded in your car pretty quickly. Now knowing the difference between watts and watts/hour will have almost no appreciable effect on your life. You flip a switch, the light turns on, and you get an invoice a month later.
While I agree with your overall point, there is a middle third option that doesn't involve labeling someone as rude. Drop the "I feel" and just say "what you said was rude".

Being labeled often requires a defensive response as it has a sense of permanence associated with it. Temporally, it is different from describing an action as rude.
I would put the Steam device on my knee when seated and playing on a train, possibly on top of a backpack that's also on my knee. I'd have to try it to be sure but I think it will work out fine.
There is a lot of skepticism around financial advisors and rightful so given the track record of many (picking insanely expensive funds, charging high fees themselves, etc.)

However, I do think there is a place for advisors not to pick investments but rather actually plan for life events (including tax stuff), which is right up the alley of this app). Having someone who could take all of your inputs, ask the right followup questions and appropriately model the likely range of outcomes on this kind of app could be quite attractive.
Shipping (distribution from local warehouses to avoid unnecessary customs surprises), taxes, certifications, (and I know it's not the case here but for some HW projects) regional electrical differences (50/60hz, 120/240v), and of course supply-- there's a number of differences that could lead to a hardware project restricting the initial launch.
Backlash or no, this will only become more common. I think we can only hope that laws and courts can keep up to protect people whose voice has been cloned without permission(perhaps stolen is the right word). Case in point, Bev Standing is a voice actor and has asserted that the AI voice on TikTok was trained using her voice.

https://www.vice.com/en/article/z3xqwj/this-tiktok-lawsuit-i...
They can't. There is a direct line between the coercive brand of discourse they promote and higher engagement/ad revenue.
"Your scientists were so preoccupied with whether or not they could, they didn’t stop to think if they should."

While interesting, the advice offered in this post is generally bad, or at least in complete. OK, so, you "cut out the middle tier..." what now? Are web clients connecting to PostGRES directly? Will PostGRES handle connection authentication and request authorization? Logging that a particular user looked at particular data? Can the client cache this data? If so, for how long? Even taking the author's premise, this is not a good pattern - a simple JSON get request still comes with a bunch of other stuff that this doesn't bother to address.

But the premise is wrong - few applications just spit out JSON like this, they also have to handle updates, and there's business logic involved in that. Data needs to be structured in a way that's reasonable for clients to consume, which isn't always a row of data (maybe it should be collapsing all values in a column, so that in the JSON the client just gets a JSON array of the values).
Do people really prefer relevant ads? I just disregard them, and it doesn't matter to me whether they are relevant or off the wall.

The only ads I specifically don't like are the ones Youtube have randomly showed my wife and I. It's only happened twice to each of us, but they were a bit adult themed. Having a child in the house, I was pretty peeved.
Between Aggression — Passivity ?
I've worked in bio and drug discovery for some 25 years. That includes building classifiers using gradient descent in the 90s (when algorithms, computers and data were all much worse). I ported DOCK to Linux in ~96 or 97. Since then I built an academic and then industrial career with some emphasis on using computing to solve problems in drug discovery, but I don't play that role any more.

It doesn't look like the models produced by this would immediately turn the challenging problem of finding, approving, and marketing successful pharmaceuticals (IE, it doesn't eliminate any real bottleneck).

There was a long-term dream of structure-based drug discovery based on docking, but IMO, it has never really proved itself (most of the examples of success are cherry picked from a much larger pile of massive failures).
I am faced with this issue of dealing with hundreds of GB of family video and pictures everytime I upgrade my wife’s phone.

The newer phones always have a higher resolution camera so file sizes keep increasing.

I would love a simple easy to use tape drive that just works. Something I could backup files to for 20-25 years.
It's a single threaded vm like python/nodejs with ffi support. So you can expect same things i.e. ipc/network to communicate with outside.
It does have an SD card slot.

However, when the hypothetical average Joe you propose picks up a cheap 256 GB SD card off of Amazon and it takes five minutes every time they reload from a checkpoint in Control, I think they will be at least as frustrated as when they ran out of space on the internal SSD.
MyBee – Distribution and API for creating and destroying cloud virtual machines
on top of bhyve, a type-2 BSD-licensed hypervisor
It would both become a tool he used (to produce initial structures to fit in density maps) and a tool that used his or her output (because alphafold requires known protein structures that are homologous to the one you're predicting).
>I know that politics are to be avoided on HN but many articles Fox News requires crossing the line into talking-about-politics territory. Faux News’s Tea-party-Republican agenda is to defund education and to selectively report on cases that support that agenda. There’s a reasonable likely-hood they could be reporting falsities in the place of facts or selectively leaving out the details why the education is so poor there.

Can you point out which parts of the article contains such "falsities" that you're talking about? Or did you see "fox" in the domain and assumed that the article must be bad? I skimmed the article and I'm having a hard time finding a "defund the schools" agenda in there.
It varies from system to system. The HH-60 Pave Hawk, for example, (USAF variant of the UH-60 Black Hawk) is well understood and on a regular maintenance schedule like you talk about. However, the USAF contract didn't require Sikorsky to hand over tech data and, instead of purchasing it, the USAF program office essentially reverse engineered a large portion of it.

Go to the JSTARS, the maintenance is almost entirely done by NG (which also bit them, they fucked up the work on one and caused it to be grounded overseas after the issue caused a fuel tank rupture during midair refueling).

There's also been a rush during Iraq & Afghanistan to push out small-run proprietary systems into the field for specific purposes, which also creates complications. Even if permitted, many of these systems end up being unmaintainable in the field due to the lack of maintenance tech data since it isn't required by the contract and lack of experience with the systems due to their relative novelty.
I don't understand your skepticism, if a deadline is in a contract, and the company is not heading towards meeting that deadline, someone has to speed up or else the client will be lost, or worse the penalty clauses will kick in. I think you're imagining B2C SAAS startups when making that assertion.

If your EULA indemnifies you from failure to provide service, and investor capital indemnifies you from failure to get revenue, then yeah it doesn't really matter what the engineers do - but that's hardly a universal principle of business.
Regardless of whether it's fair use, copilot wouldn't be possible without the enormous amount of person-hours of work that has gone into writing the code it was trained on. There should be some kind of compensation for the content creators when their work is used to train models. The fair use argument is that "I could see it" is enough to justify no compensation and no say in how their work is used.

Legal? Probably. Should we do better? Probably.

At the very least, it should be opt-in. We'll probably need new IP law to make this kind of thing opt-in.
Honest question: since AlphaFold doesn't really _solve_ the protein folding problem (it's NP-complete after all), but only _approximates_ solutions very well, what are the real impacts of this? Isn't a good approximation of a protein enough to cause unexpected problems? How do we know that an approximate structure will perform the same as the correct solution?
Not just one-to-one (injective) but also onto (surjective). :)
> I am personally vaccinated, but I think it's reasonable to let individuals make that choice.

A virus doesn't infect you and stop, it uses your body to infect others. Public health is the opposite of "my body my choice".

A simple enough distinction to make if you care to do so.
Historically, this is AWFUL for gaming on Linux, since NVidia is a terrible company which takes forever to get their drivers working on/with new features (Wayland, kernel modesetting, new kernel versions at all for a long time). You seem to be taking a lot of assumptions about what gamers want/need on Windows and cross-applying it.

Steam (via Proton, mostly) already does a lot of development work, and it doesn't care which distro it's on. "Oh no, I updated my kernel and now my graphics drivers don't load at all!" is incredibly common, even with DKMS. Sometimes (mostly) bugs get fixed in Mesa or whatever. Often, new subtle bugs are introduced when a new Wayland/Pipewire/whatever feature goes GA. Having as few moving pieces as possible (by using an LTS distro, or at least something which isn't rolling with upstream and has a modicum of QA) lets you optimize the pieces you need to without worrying that this or that API is going to change underneath you.

Intel and AMD drivers do not have this issue, and Valve was smart enough to not go with NVIDIA, but "I want to be up to date" is a terrible experience.

Additionally, it generally makes for a much less reliable/stable experience (gaming or otherwise) because `pacman -Syu` may at any point break something because you didn't read the release notes, or "mostly" stable features were committed upstream then released so the userbase can put them through their paces and report bugs the developers didn't encounter.

Users of Arch/Fedora Rawhide/whatever accept this, but someone who buys an OEM gaming machine does not need or want this.

Just to note, I AM saying that Arch is unstable. I've been using Linux for 20 years, and I've had my time with Gentoo and Arch. 99% of the tinkering users do is reproducing the work of professional developers at distro vendors who spend a lot of time and effort making sure you never encounter the problems Arch users revel in fixing at all. Sure, you can tell yourself that means you "know" more about the system. But that is time invested that you could have spent doing REAL THINGS, and solving REAL PROBLEMS which are not un-breaking your distro.
Primarily the community that previously depended on homology models.
Same, except just yay.
As a Mac user, I'm very interested as well. I don't play any games nowadays because I cant justify spending all that money for a latest generation PC, let alone the space it takes.

If I can have a dockable PC that can churn decent frame rates, It's just a matter of switching the input on my monitor and switching the bluetooth mouse/keyboard to it. For me, the fact it's portable is just icing on the cake to be honest. I'd buy it even if it didn't have a screen or controls to be honest.
Sarcophagus $Sarco Memes Contest Bounty
The Sarcophagus Ambassador's Community is holding a Bi-weekly Meme contest with a Pot of 10 SARCO per entrant! more info here https://www.sarcophagus.community/memecontestform
> All-or-nothing thinking – which psychologists call ‘splitting’ – is a symptom of certain personality disorders.

And yet it permeates American culture right through its core.

With me or against me. Good or bad. Right or wrong. Amazing or horrible. Left or right. Freedom or communism. No compromise.

As a corollary, I wonder if it follows that the American culture counts as a personality disorder. (Let the downvotes come!)
That's fair; apologies. I'm too late to edit it now but if some passing mods see it and is able to alter please do so.
Also I would say that really they just made improvements to protein structure prediction, not protein folding which is the dynamic process by which proteins reach their equilibrium fold.
I unironically love that scihub has become such a default that people don't even notice download buttons on paper pages any more.
Yeah, they're more focused on screwing the content creators rather than the consumers.
You're very welcome! Throughout the course of the pandemic, I went from knowing only a little about personal finance and financial independence, to researching everything I could get my hands on and eventually building this tool. Working on it as my main side project is one of the things that's kept me going through the pandemic months, and it's awesome to see others now enjoying it too.
37€ for 1000/300 in Spain, one VoIP phone number included.
Mixed Reality Toolkit with Catherine Diaz [audio]
Louis would be first to tell you that it is all related. Many manufactures have moved to this model. In his space he is specifically seeing 'just toss the thing and buy a new one', when the real fix is 30 cents worth of resistor and a couple of hours of someone's time. The military is no exception. But they may have the bargaining power to fix it for themselves at least. Think of it more along the lines of what mcdonalds did to themselves. Their milkshake machines are broken (10%-20% of the time) because they outsourced fixing it to a third party. The third party has no reason to really fix the issue when a good chunk of their income is repeatedly fixing the broken thing. When the reality is poor diagnostic and poor info to some teenager who was told by his boss to 'fill that thing' and he did it slightly wrong. Mcdonalds could fix it real quick if they just stood up to their third party and said 'fix this, like last week'. But the companies have 'political' issues where people in mcdonalds are incentivized to keep it the same. Also parts of the costs are take on by others and mcdonalds proper does not really have to deal with it. The military has similar issues.
Also not a lawyer, but I've been around ML for a while. The question makes perfect sense to me!

It takes some amount of time to comply with a takedown notice. For example, time passes between receiving Alice's notice and taking down Bob's repo.

I would expect Copilot's model(s) to be retrained periodically in order to remain relevant. The next retraining could exclude Alice's code. That might be a longer window than the case of the repo takedown, but as long as it doesn't take too long they might be okay?

There are incremental training approaches that evolve models over time rather than completely retraining them. In my experience, complete retraining is a far more common approach because the highly path dependent nature of incremental training can lead to outcomes that are hard to manage. For example, what if you discover bad training data like repos that collect anti-patterns? Or Alice's takedown notice? You typically want your models to be able to "unsee" things and that's hard with purely incremental training. Even when incremental approaches are used, there is often an occasional complete retraining to overcome such issues.

To be clear, I have no idea what training approach is used for Copilot.
I would love to try out your platform for my current hiring needs. Good luck with the launch!

One UI feedback for your website - On your contact form for companies, text isn't visible when the form field is not in focus. The text colour matches too closely with the field background.

Edit - Also, on submitting the form, the success/ confirmation text did not appear in the visible window. I had to scroll up to see it
Clinical studies now indicate that Covid immunity will be long-lasting.
I worked on a Django project recently where we were generating GeoJSON from data in a PostgreSQL table.

We investigated using tricks like this to generate the JSON directly from a SQL query - my notes here: https://til.simonwillison.net/postgresql/constructing-geojso...

The performance was a big enough improvement that, had we been bottlenecked on this particular operation, we would have shipped this (I'm afraid I don't have notes on benchmarks).

We only decided not to ship it because of concerns about the ongoing maintenance overhead, since we had other Python code generating GeoJSON that we would have still used - so we would have ended up maintaining multiple implementations.
> Real number counting is a bit more loose. To find the numbers between .1 and .2, you find all fractionals of a given size, normally 1/10.

Unfortunately the fractionals method does not work, since there are numbers (in fact, uncountably infinitely many!) irrational numbers which cannot be expressed as fractions, which are nonetheless real numbers (such as the square root of two and pi).
Shameless plug: I made bson-to-json for more or less the same purpose with MongoDB: converting the raw BSON response from the DB directly to JSON strings. Saves lots of CPU cycles and GC pressure.

https://github.com/zbjornson/bson-to-json
Some links:

https://www.edx.org/course/paradox-and-infinity

https://ocw.mit.edu/courses/linguistics-and-philosophy/24-11...

https://www.amazon.com/Brink-Paradox-Highlights-Intersection...
How heavy is 1KG of iron?

Asked because not asking is apparently stupid but the question isn't.
What would it take to fix it?
many of these resources are available, it's mostly that academic scientists don't have the time, money, or expertise to manage large datasets. However, the community has maintained high quality MSA database for decades and that's exactly the work that DM drafted off.
I’ve been using Arch as my only OS on desktops and laptops for years now. Maybe I’m just lucky but in my experience it’s been incredibly stable. I’ve only run into one issue with updating packages using pacman and it was a Postgres + PostGIS conflict caused by my own configuration mistakes (easily fixed). I imagine most updates for the Steam Deck will either be from the core repositories or through Steam itself though, so the same issues you might run into when installing bleeding edge packages from the AUR shouldn’t apply.

As far as why Arch, I think it’s a great “build your Linux OS” distribution that gives you a solid foundation to expand into the bespoke system of your dreams. On my desktop, I have a personalized computing experience using Wayland + Sway, PipeWire and only the software I use. That same DIY principle makes Arch a compelling option for anyone looking to build their own distro; Manjaro is one such example and it’s the distro I used before making the full dive into Arch.
Can I install Windows 11 on it?
Maia, a human-oriented AI for chess
...and "newer" is a relative term - motion compensation first appeared in H.261 (1988), I believe.
Wrong, you can install whatever OS you want, the developers even said so. You have a lot of freedom.
It's amusing how quickly we start taking things for granted.

Right now SpaceX is the only company that recovers their orbital class booster. And that didn't happen until 2016! Prior to that, everyone dismissed landing rockets as impossible. Given the lack of competition for launch vehicles + the fat defense contracts being awarded, there wasn't much incentive for the incumbents to even try to bring the cost down.

Designing a rocket that can land and be reflow is a multiyear process. As other comments have said, more design changes would been needed to F9 to make it more reusable, those changes have tradeoffs. Instead, SpaceX chose to invest in a new design and more capable vehicle.

Other launch providers like RocketLab and Blue Origin are pursuing reusable vehicles.

"Why has no one done it?" give it time... it will happen sooner than we probably expect.
> Cornet has now begun his new job at Twitter. And while he is more hopeful about the company's ethical core, that's not prompting him to put down his pen.

So in the end money and status wins? Maybe he should make a sketch about that because less than 1 in 100 people would consider Twitter to be an ethical company. All in all Google has the upper hand of good delivered to the world compared with Twitter.
I haven't worked on the drug-side of things, but here my bio perspective: It's kind of out-of-vogue, but consider the "lock and key" model of proteins and small molecules (drugs). For drug design, what you want to do is get a key that fits just one lock (to pull whatever lever) and not others (to avoid side-effects). It's relatively easy to find a molecule that fits a protein, because that protein is what you might spend years researching and probing, but it's tricky to check if it does anything against ~100,000 others in humans. If you could do an in silico computational survey to be like, oh, maybe it'll target this accidentally, you could spot-check those in vitro, and/or stick on some other atoms to your small-molecule to make it not fit that off-target.

Holy grail, IMO, though is being able to design de novo protein sequences (to make "biologics", aka engineered protein drugs) that can a) target (bind/block/enhance) or do (chemical reactions) what you want and only that, b) are easily synthesizeable by bacteria/yeast (cheap to make), and c) are stable (easy to transport/store).
A pal got one of those when we were in college, and it will surprise precisely no one that we mostly used it to sample rude words, and then have the device play its demo song using the rude word as the voice.

Quality entertainment, for SURE.
Those are terrible prices.
I view it as a more inconvenient, less effective(but still effective), but more obtainable(in many states) form of Suboxone.

It can stave off withdrawal, cravings, etc. And it can get you high and be it's own addiction. It's still an opiate, and can still be very potent(in high enough doses). The main limiting factor is the pure volume you'd need to ingest to get the potency of a fraction of a gram of other opiates
21 Years of Programming Experience Distilled, Lessons I Learned as a Dev
I used to avoid things like stored procedures like the plague, because of my fear that crucial business logic would end up outside of version control.

These days I'm comfortable enough driving EVERY database change through a version controlled migration system (usually Django migrations) that I'm not concerned about this any more. It's not hard to enforce version controlled migrations for this kind of thing, provided you have a good migration system in place.
I don't think the original concept is was very misleading. Essentially the idea was that if rulers infringe on too many freedoms, the people are morally allowed top rise up and kill them. Every day that you aren't trying to overthrow the rulers, you are affirming the contract.

We take this for granted today, but it was not always the case. Prior philosophy essentially held that the rulers had a God given right to power, and people had a philosophical duty to obey, no matter how they were treated.

There has been a lot of scope creep since the 1700's increasing the scope of government expectations, and deemphasizing the obligation to take action and revolt if you are not happy with the balance.

The original idea was very real politik, where people are only entitled to what they are willing to risk their lives fighting for.