skysight-inc/HackerNews huggingface dataset:
> Check the table with reports and fatalities by age, and the paragraph interpreting the data. Together with [2] you can calculate the fatality rate for the 20-29 group. In the end you'll end up with a fatality rate for women age 20-19 in the range of 1:150k-300k (quick back of the envelope calculation).

I really can't, because there is no information on which age group got which vaccine. The AstraZeneca vaccine has been restricted in the UK for under-30-year-olds as early as April.

Here is a study (Italy) that estimates the risk-reward ratio (fatalities caused vs. prevented) is unfavorable for the entire below-30 age group, including males:

https://www.medrxiv.org/content/10.1101/2021.05.07.21256826v...

> The source I posted is a metastudy, computing IFR based on seroprevalence from many different countries, so PCR tests have nothing to do with it.

This is true, but PCR tests is how we count actual infections and deaths. When calculating the risk of getting infected, IFR alone doesn't help me, I need PCR tests as a metric of how many infections are actually occuring.

Alternatively, I could use seroprevalence: Assuming that seroprevalence is 10% (way higher than in your somewhat outdated source), then over the course of the pandemic, assuming IFR in our cohort is 1:25K, then the absolute risk was 1:250K - roughly on par with the "vaccine fatality" scenario. This is just an example to show that the numbers aren't clearly in favor of the vaccine.
https://en.wikipedia.org/wiki/Stanford_Tree

"The "Tree" is representative of El Palo Alto, the tree that appears on both the official seal of the University and the municipal seal of Palo Alto, Stanford's nearby city."
They’re building all the eCommerce capabilities from scratch in Elixir? Or is the latter just part of the stack?
Thank you, this is really helpful and gives me some good starting points. I had no idea the mapping wasn't 1:1!
Anyone who knows Rails or Django can pick up Phoenix and anyone who likes Elixir is going to be the kind of person you want to hire.
When it comes to base load, nuclear is pretty interesting. I remember reading that some plants sell electricity at below cost during low periods (nighttime in some locations), since they can't ramp the reactor up or down quickly.

It's a situation where both intermittent renewable sources and nuclear plants would benefit from a way to store excess produced energy
I don't think your depiction of who holds the power in Canada is entirely accurate. The power you are speaking of is wielded more by suburbs. In Ontario that area is referred to as "the 905": the regions of Halton, Peel, York and Durham. When it comes to issues like car ownership, I suspect that many suburbanites want their SUVs as much as rural folks do.

I also don't think this legislation "shaft[s] the rural folk". Climate change is coming for all of us. On Tuesday we recorded the highest temperature ever in Canada, 47.9 C! Speaking optimistically, I would like to think that Canada is taking actions to protect all Canadians.

Unfortunately, the truth is that we need far more potent legislation than this. But there are many sacred cows in Canada when it comes to meaningful action on climate change — such as actual cows. If Canada were, for instance, to tax agricultural products like meat and dairy in such a way that their climate impact was no longer externalized, that would indeed be seen as "shafting the rural folk". But I don't see that happening any time soon.
I'm in Oregon and I didn't realize that.

Don't mean to be too much of a jerk, but I may adjust my tipping downwards. I typically do closer to 20%.
This is how US "blue states" work.

At least according to the rural population.
This is a good point and it will be interesting to see if something like copilot will get developers/companies to adopt a language that is better supported by AI.

Edit: You are honestly downvoting me for saying something that might actually happen. If copilot lives up to the hype, but for a limited number of languages, this can have a profound affect on what languages people might decide to use in the future.
Maybe I should think about building a mechanical version ;)
> which makes no sense because there was no specific bridge in the first place

The context is that nobody would want to bicycle over these bridges in general because where these bridges are generally used it is not legally or physically possible to get to them on bicycle.

The point therefore is your question doesn't make any sense if you know the context.

Look at the other comments saying the same thing as me if you want another perspective to help you understand if you're struggling.
I mostly agree, this is always my thought about this stuff. As you say, it is so far in the future that a new government will be in power, and can freely reverse these decisions. Or we'll just end up there anyways because that's the trajectory we are already on.

Something more immediate would have a bigger impact, probably a tax, but taxes don't often work in politician's favour. We have rebate incentives for electric cars, but that only really only helps to swallow the price difference. We can't rely on peoples morals only unfortunately.
Did we work for the same company?
Majority of Windows licenses are sold by oems with new pcs. People updating their old computers means no new licenses sold.
Not one mention of Apple and their M1 chip. WSJ reads more like advertising than information, only serving to highlight how “bright” Intels future is.
My newborn was diagnosed with Sturge–Weber syndrome and mRNA sounds like a potential solution.

The issue is it's rare and united States government approval is expensive and slow. Not something that works well with a degenerative disease.

I'm a bit insane right now admittedly, but given my background and wealth, I'm considering DIY. The technology is there, government is the hold up. Would you let your kid have seizures and cognitive problems because of red tape?
> It was nearly a decade later that the first consumer multicore x86 processors started coming out (2003 if I've tracked down the right dates).

Talking about consumers, ABIT BP6 came out in 1999.
I mean it in good faith, and I am just trying to challenge how throwing out the dna paradigm explains things better. I agree that metabolism plays an important role in cancer, and we don’t fully understand it. But, I take issue with your original claim that the current paradigm is wrong because it explains things that I have personally seen in the lab when I did lab workup, in my clinical work and in my family members who have cancer and are being treated with medications that work.

As to the atp issue, yes it is involved with metabolism but so so much more. If you have time read The Biology if Cancer by R A Weinberg. He does a good job of exploring the historical investigations as wellas the science.
I love e-ink and these look really cool, but yeah, that price. Where are you currently getting your displays? You may be interested in EPDiy [0] (controlling cheap left over Kindle DX screens with an ESP32) and Inkplate [1] for some inspiration on cheaper sourcing.

For reference: the 6" Inkplate costs around 100€ and I think you could fairly comfortably build a 10" EPDiy device at around that. That's without all the fanciness of course, with it I reckon it should be possible to sell these things at around 200€ each, which would probably make them a lot more interesting to people.

That said: I'm excited for color e-ink screens appearing on the market. The amount of devices released lets me hope at least some will make it to a secondary market.

[0]: https://hackaday.io/project/168193-epdiy-976-e-paper-control...
[1]: https://inkplate.io/
And one huge reason is that auto manufacturers haven’t started devoting serious resources to EVs until recently. Technological progress isn’t preordained — we decide where the advancements will be.
Retargeting is one of those things that everyone is 99% sure it's safe. But 99% sure in millions of people means thousand of problems and perhaps deaths. So before signing any authorization it's better to wait until the clinical trials are done instead of using gut feelings. (Waiting too much is also bad, so it's a tradeoff.)
At this point, I don't know what job I would like. The biggest part would be a place that actually follows their own policies and doesn't violate them to the detriment of the employees. Sadly I feel that would happen anywhere.

I could work with $80k per year if the healthcare and other benefits are good. It would also be nice to have the ability to advance and make it to a tech lead at $120k.
> a bunch of dirt roads are in the remaining part

If you've never been, do yourself a favor. The parts out west with the dirt roads are the best parts.

Here's a little road trip I took late last fall on "the dirt roads" - https://youtu.be/pyQMt8om9Io?t=973
> Nissan estimates the batteries will outlive the cars by about 10-12 years

I was about to make a joke about Nissan's build quality, but Nissan beat me to it...

> The company sees the LEAF's reasonable life at about 10 years.

Yikes, the average age of a vehicle on US roads is 12+ years. I know they're in the business of selling new cars, but damn.
To GP's point, the poles are privately owned. The Cable TV company put them there, or the telephone, or other utility. If you want to use space on their poles, you have to rent it, or install your own poles. Both happen. On the road I live on, there are power lines on one side of the road which also carry telephone lines. Cable TV (Comcast) has poles on the other side of the road.
The response to this should measures to increase competition rather than government managed providers which kill competition even further. For example:

* fewer regulations

* additional taxes for monopolies

* tax subsidies for new internet providers
Depending on the carrier, his personal location could be narrowed down significantly.
If your grandparents have WiFi at home, you can do exactly that. There is a mode to periodically fetch images from a remote URL.
> It seems to me that they want media/experience/communications-rich features removed from the browser, in-lieu of your local OS/software suite.

I got this impression too. I dislike that their solution seems to be nerfing web-browsers in hopes that developers begrudgingly go back to desktop apps instead of buffing the tools used for building desktop apps so that they're what people want to develop.
I know I'm not the only one that has wanted to recreate the front of a CM-2 with LEDs. Here is a good reference for the "random and pleasing" pattern of blinking: https://trmm.net/CM-2/
This is not good for Intel, though I will say that this is likely not anything that is within Gelsingers direct control. Likely years of poor decisions, middle management rot and other factors led to this.

If I was an Intel investor, there are some positive signs. The fact they are looking to diversify themselves a bit and potentially decouple their fabs from their IP/design is actually a huge deal.
https://web.archive.org/web/20210415072450/https://neeva.com...

We could read this like a confession from ex-Google managers:

"There are technology products [like the ones we acquired at Google] that work better when they [anthromorphising the software] know some information about you, like your interests or what country you live in. However, companies today [(read: Google)] collect whatever information they can about you and store it indefinitely. [Yikes!]

Additionally, companies [such as? Google?] need to offer you controls that are easy to find and give you real ownership over your data-not just lip service. [What the heck is "real ownership"? Submitted/uploaded data belongs to the user. Larry Page himself said this in a televised interview. Are "privacy policies" considered "lip service"?]

For example, tech products [like the ones we became familiar with at Google] rarely need to store your location history forever. A better default would be to store this data for 90 days, while offering you the option to let the company [Google] store it longer if that is your choice. [Why 90 days. Why not 0 days.]

Do you know all the different ways technology companies [like Google, our former employer] use your browsing data? Your IP address? Your name and profile photo? Companies [such as the one we worked for] can get your personal information for a purpose that benefits you, but then use the data in whatever way they want going forward. [How clever. And what can be done about that. What if Neeva does that? What recourse do users have?] Products [such as the ones we saw at Google] ask for your phone number and email address so you can recover your account in case you get hacked, but then will use this data to report your online purchases to advertisers."

How and why did Neeva arrive at the 90-day data retention policy.

Why cant users have the option to have data stored for 0 days.

Why cant users request to have their data deleted immediately.

(Neeva is getting paid regardless of whether they collect or store data, other than the minimal data required to administer user fees.)

Why does a "paid search engine" need to collect and store more information than, say, a VPN provider. For example, collecting more data than than username, email address, and payment details.
> That said, I am also shocked by how many full time developers don't take the time to understand their own code. Let alone the libraries they use.

Own code would be bad but libraries? That's kinda the idea of an abstraction layer.
> It is rare, in the US at least, for any representative or direct democratic situation to ask for unanimous consent. Someone will almost certainly disagree once you get past 1 voter (or one representative), and possibly they'll disagree with themselves.

Just because something passes by a margin of, let's say a hypothetical margin of 51/49, you're right that it didn't require unanimous consent but if you ignore the concerns of that other 49 and decide not to at least understand, represent parts of or compromise on certain aspects of an issue you're going to just create a situation of hostility for a large group of people that eventually leads to bigger issues.

As to your explanation/example, sure and I don't have an argument against that because I don't disagree with it. I would vote for municipal broadband and think the state is over stepping it's bounds here.
> I came to recognize that my relationship with hard work during my college years was not healthy

Exactly, it's like we are celebrating a mania.
Ask HN: What are/were the main bottlenecks preventing you starting a company?
Many people I speak to say one of the following:

- having the right idea
- financial security
- finding the right team

That said I increasingly think there are ways round each: especially the first and second because of incubators and funding, so I'm curious what people's reflective reasons are, especially people who see themselves starting companies some day but don't feel now is the right time.
> Retargeting is one of those things that everyone is 99% sure it's safe. But 99% sure in millions of people means thousand of problems and perhaps deaths.

You seem to be assuming “99% sure it is safe” means “sure that its 99(.9)% safe”. They are...not equivalent.
Can you invite users or does everyone have to be on an endless waiting list?
I agree. Companies that did invest in environmentally friendly technology should be rewarded, and companies that didn't should be punished.

Legacy automakers had tons of time to innovate and switch to more environmentally friendly tech, but they chose not to. The government should accelerate their demise if it can help the environment, they can either get it together in a few years and improve their EVs, or they can sell their assets and expertise to Tesla or other electric manufacturers when the policy causes them to go bankrupt.
Video games probably taught me more than any other activity in my youth. I also played football and was an avid reader of fiction.

I don't really play them anymore because I played competitive games (As opposed to very casual or story driven games), and being good at games is no longer a priority to me. It takes a lot of time and effort to maintain your skill level, let alone increase it.

I definitely still see value in playing competitive games, but I think I've already extracted most of that value.
Intel put itself out of business since all the world's computing needs can now be done on one CPU.

Or, perhaps, lower unit costs of computing lead to far far greater demand for computing since it became practical to apply to more domains.
Many parks are basically taken over by tents. Can’t go play with kids there anymore.
Hmm I wouldn’t say the Leaf was weak. A short range battery electric car makes sense in Japan and they were very popular in Silicon Valley where commuters could charge at the office.

Seemed like a great way to get started in the industry and unlike every other conventional automaker Nissan started in 2011 when Tesla was the only other major player. And unlike the Teslas at the time, the Leaf was affordable.

EDIT: Took a quick look at sales figures. In 2014 Nissan sold roughly twice as many leafs as Teslas sold in the US according to the following links, though Tesla rapidly grew beyond that while leaf sales slowed.
https://carsalesbase.com/us-nissan-leaf/
https://carsalesbase.com/us-tesla/
The GP's example doesn't involve invalid datetimes. The datetimes aren't out of bounds or invalid in any way that a check constraint would detect. They've just become factually incorrect ("bad data"), because they are derived data that wasn't updated when the derivation rules changed (i.e., regulatory changes).

If you're storing future datetimes that semantically represent wall clock time, you need to store the locale time plus the full time zone (such as America/New_York) so that your program does the right thing in response to any common regulatory changes that happen after you store the value. Storing the time zone abbreviation (e.g., EST) is inadvisable, as computers sometimes care whether you asked for EST vs EDT. Storing the time offset (e.g., -500) is incorrect, as it has the same pitfalls as storing UTC - you're precomputing the locale's expected time offset at storage time, and your data won't automatically be corrected if time regulations change.

If you're storing historical timestamps, UTC is fine because you can safely convert it to whatever time zone you want to display, knowing that changes to time zone / DST regulations tend not to affect the past.
> If this results in more overall programmers or enabling existing programmers to make products quicker than before, it's a win!

I don't think I really agree with this sentiment. "More programmers" or "faster programmers" is meaningless (or even actively detrimental) if the quality of their output is lower. It's even worse if their output is plagued by subtle bugs, as AI systems are likely to produce.
I grew up on a dirt road in rural Canada. I'd be happy to live in such an area and have a government that takes the local population's needs into account. The GP's dismissive attitude of "you and a bunch of dirt roads" is exactly what the rural population is up against.
How to get in bed with your boss and get THAT promotion in 30 days
Extraversion is a relatively plastic personality dimension
Testify Your Intent on EOS
Virtually none of the recent crop of UMPCs have them. At that size, they just don't fit in the screen bezel. One model has a camera in the hinge, but most just don't bother.
If they're doing it right it shouldn't be an expense, the tax payers should be making a profit off of it. How much money does comcast make?
Does the municipality have any role in the administration of the service? If so, did they have that role last year? If yes and no, respectively, how is that not an expansion? (And if the municipality has no role in the service, in what way is it municipal broadband?)

It may very well be a good program and if it is, I'm in favor of it, but it seems like it's clearly spending taxpayer-funded grants and likely has an expansive (even if slight) force on government.
Undoing of those policies is very unlikely.

The people (i.e. voters) overwhelmingly support action to limit climate change. That's the reason those laws are politically viable in the first place.

Once enacted, trying to undo them after being in place for 4 years will not only be difficult procedurally but politically suicidal.

It won't happen unless the political party in question has so much electoral buffer that they can ignore what 70%+ voters think about the subject.

Furthermore, if you believe that the climate is changing for the worse then every year will be even more devastating than the one before.

Power cables and roads in Oregon melting due to extreme heat? Next year even more cables and roads will melt.

Every year the public support for climate action will grow and opposition to it will become even more politically suicidal.
In the case of a ship or sub, in the event of both catastrophic failure, or even a material leak, its likely going to end up in the ocean. Water is an excellent radiation shield (though I guess it doesn't matter much, since no one would be around), and even a materials leak gets diluted until its not an immediate risk. RIP ocean microbes though
> So mRNA-based techniques have a lot of power and a lot of promise. But there’s definitely a low-hanging-fruit area here, and that’s infectious disease vaccines. Beyond that the promise holds up, big-time, but the difficulties mount up as well. It’s going to be a long story with a lot of plot twists, but I’m glad we’re telling it.

Just want to emphasize the conclusion, because if you stop reading before the end, you might think that the article is dismissive of mRNA, its not, just realistic in the remaining challenges for some of the more ambitious outcomes of it.
> Are there any open source licenses that explicitly forbid use when training an AI?

Github/OpenAI's defense is "training ML systems on public data is fair use" (https://news.ycombinator.com/item?id=27678354). Unless this assertion gets invalidated in courts I think they mostly don't care about wordage in your license

> I want to release some open source code, but I don't want to make the mistake of training my replacement.

Most of a software engineer's value is not in the code they write. By far and large employers care instead that you solve their problems. Code's just a by-product, means to achieve that.
Why am I not surprised - the same idiot government who introduced fines for free speech the other day.

Meanwhile the EU-level CO2 taxes will be applied to make sure that the ICE vehicle owners' lives remain miserable until, and beyond, 2035. What a shithole.
That’s not what I would consider ‘commercially available’ - it’s a project with software and some hardware recommendations to build it yourself.

I’d pay decent money for an actual off-the-shelf, working set of these.
Conscienciousness is the easiest dimension to change over time with incremental intervention, so yes. Trauma can also change personality, but either way you wont go from bottom 1th percentile to top 99th without the task consuming your life.
In New Zealand we have construction not dissimilar to the USA, from how Americans in HN describe house construction. 100+ year old wooden houses are common here.

Construction evolves due to avaliable resources and local conditions. Transplanting a technique from one country to on other won't necessarily work.

If you have earthquakes such as in NZ, USA or Japan building concrete houses does not make a lot of sense.
How many accounts are you posting under?
Like wouldn’t be entertaining without the License Nazis. No code for you! (Seinfeld reference)
Depends on your viewing distance. If viewed from a few feet / a meter, that resolution is probably enough. The contrast ratio might be the bigger problem. From a low-effort search, photo paper has a contrast ratio of 100:1, while e-paper has a contrast ratio of only 12:1. Photos displayed on e-paper are going to look washed out.