skysight-inc/HackerNews huggingface dataset:
I had a very similar idea, but I was thinking it'd be potentially employed against a geopolitical adversary with a large population and a tight or net import food supply. It could further put strain on the government to cope, thus reducing their threat.

Lack of protein in population diets probably also greatly reduces economic output.

Scary stuff, and anyone could use it against us.

You wouldn't even need gain of function. Just a more efficient vector. It seems almost impossible to get a virus to code for a carbohydrate pathway, and it would quickly be evolved out since it doesn't mediate adhesion or any critical function. Granted, there's a similar problem with supplying the alpha-gal in a parasite pathway.

Low tech air dropping lone star ticks seems like it would still produce the desired effect for the aggressor. And it'd be geographically limited impact unless the species spreads over time.

Biological warfare could be terrifying. We've just seen the first accidental use of it (assuming lab leak is what happened).

Back when I was a biochemistry student I had less scary thoughts, such as tranfecting the THC biochemical pathway into Kudzu to make it impossible to control. (I'm not into drugs but think the drug war is a drag on the US and its neighbors.)

Biology is like the computing field, it's just not as completely developed and fast paced. That could change in the future.

edit: again hit with the HN posting rate limit, and I'm not even downvoted. I think I have interesting insights given my background, but whatever. :(
Fun note at that. If nothing happens the CIO states boastfully how their spyware prevented crap from happening. If shit happens it is elaborate stuff we need more protection against.
This is interpretation of an AI system, something like mechanical turk where you get a feeling that an objective is achieved by the system but in reality there human doing thr task.
One thing which makes 2% seem much worse for a grocery store is their thin margins.

The gross profit for just about anything at Amazon is going to astronomical compared to just about any food category.
And it is not that bad - base45 packages nicely in 11 bits; so compared to exactly the same payload in binary - there is just a few percent difference in the end in pixels/cells on screen.
Take some time off, and slowly go back to coding with some personal projects, alternate with outdoor activities
The Meaning of Life – Sam Harris
Good, the thought that my own country would try and block me from the one tool that allows easy communication to extended family in China is really just mindblowing.

No, china doesn't operate fairly. Yes, it sucks, and something should be done. But no, the answer isn't to turn around and punish your own citizens for it.
Not sure that's more realistic. There is often enough human capital necessary to build certain things in certain places, just not at the lowest price.

> This can be addressed in large part by making immigration easier

Not if local laws don't provide the same competitive edge.
Understanding the original context/culture in which the literature was produced can be very helpful (although I'm not saying it's 100% necessary).

One illustration is that of a traveler. If someone was traveling to another country with a drastically different culture than their own, they would be expected to make the effort to learn the customs and differences in that culture before they went. This would help them understand and experience things in a whole new way, gaining a broader perspective of the world than just their own ways of thinking. Essentially, taking the time to understand this other culture will be the difference between a "good" vs "bad" travel experience for them.

I believe it's similar with reading and trying to understand ancient texts. It's the difference between learning something new that can grow your perspective on the world, versus reading your own perspective into the text and simply reinforcing the ideas you already had.
This is rather idiotic to petition for that. This is what will happen anyways. As soon as life in large space stations will be possible, billionaires will go up and stay living there all or most of the time. Trillions will be made in space. They will go up and not looking back.
If you have the savings, quit. Take 1-2 weeks and don't look for work, just enjoy the lack of responsibility. Then, when you start waking up feeling curious about tech/data/whatever, start to poke around your network and see who's hiring. Update your LI to looking for work. While you're not interviewing play around with tech you thought was interesting but didn't touch. Just kinda hang out and enjoy yourself until you get hired somewhere else.

If you don't have the savings, just start doing a worse job. Prioritize starting on time and leaving on time over everything else. Lean into using personal days whenever you feel like it. Push hard to get out of meetings that aren't valuable to you or add to your stress. Start putting money away so you can quit when you're ready. Start looking for a "life raft" job - something that isn't offensive and low stakes, just to get you out of your current gig. Doesn't have to pay well or really be interesting. Just get you out to a fresh start.
The twitter thread tries to explain the concepts without the math

https://twitter.com/labmlai/status/1407186002255380484
You have unprotected servers public facing on the internet? Cool. That's definitely not something you should be concerned about and addressing immediately.
A bit further down:

> Please respond to the strongest plausible interpretation of what someone says, not a weaker one that's easier to criticize. Assume good faith.

Maybe that's reasonable formulation of their opinion, and you shouldn't assume it's snark.
Sure, and there's a lot of work in this area to predict sepsis in specific subgroups, but as with a lot of AI I think we're a long, long way off a 'general purpose' sepsis detector. For various reasons sepsis just presents differently in different patient groups so one person's risk factor is another's protective factor
https://suckless.org/

I've been happily using non bloated tools for years now.

Obviously this isn't for everyone. ;)
Václav Smil at Driva Climate Investment Meeting 2019
> they are not meant for public access

Then, I think, you need to implement "reasonable measures" to secure them. Otherwise it's like putting your stuff out by the curb.
In other words, bricked by the vendor themselves.
I'm not sure that "what's less unsettling" is a good criteria. Also you only provide two options, which given the unknown character of the phenomenon, would count as a false dichotomy.
Half the struggle in exploiting someone behind NAT/FW is getting them to engage with your infrastructure. Your attack surface is massively increased once you visit a website with your browser for instance.

I see other comments mentioning logging into random IPs over ssh. Now i trust the ssh client implementation more than most software, but it's easy to slip up and enable ssh agent forwarding for instance.
I don't know how to deal with it but I'll tell you what not to do. Don't let it build up and overtake you like I did this year. Find a way to deal with it or you can feel like your world is falling apart.
> 60hz monitors were practically non-existent

?? 60Hz progressive scan was fairly standard for SVGA 20 years ago; people looked for 70+Hz displays because they were bothered by the flicker (my college roommate in 2001 ran at 1024x768@75Hz rather than 1280x1024@60).

800x600@60i was the bargain-bin monitor even in the late 90s. By 2001 you could get a used 800x600@60p or 1024x768@60p monitor for nearly free if you lived anywhere that had companies upgrading to higher resolution.
It was tested pretty extensively (and was already in use in public transport) -- including tests in muddy fields @ festivals with bad wifi and bad light.
>Either someone pays the fee and adopts the thing, or it goes to the farm upstate.

Yeah, and everyone else (but not Amazon!) will pay the "upstate farm" fee, aka environmental damage, for eternity.

Aren't externalities great?
Microbes and solar power ‘could produce 10 times more food than plants’
It really is a lovely place. I grew up next to the Black Creek dam, used to take a coffee out there and just watch the sun rise.
FWIW, I seem to remember that taxation is also a pretty good instrument against inflation.
The Record Temperatures Enveloping the West Are Not Your Average Heat Wave
> I had to read this a few times to understand that this isn’t saying that Pocketlang is not written in Wren

I had to read that a few times to understand what I think is an unintentional double negative on your part.
It's very easy for people today to forget the 1800s that had significant periods of deflation and thus one of the reasons the federal reserve was created... although they allowed deflation to happen during the great depression as well. There is certainly some debate that can be had about the way to easy money policies that exist today (and I do think it's far too dovish), but people need to learn their history and realize the damage that deflation does.
I guess that although you can make some downtime and definitely the nutrition and exercise will help but you also need to be honest about your job and role.

All the self-help in the world won't work if either you are not well-suited to the role you are in, and are therefore becoming stressed or otherwise the work environment/management is toxic and doesn't suit your personality or expectations.

Even when I am tired, I can get into my work because it inspires and challenges me and is within my ability level (but isn't too easy as to be boring).
There's also Canonical and Debian in the distro world. Elastic is still around, seemingly panicking. Docker still exists for now, but probably should have sold when they had the chance. Grafana seems to be doing fine. Rancher got by without even trying to sell enterprise licensed versions of the software, just by selling support, and was recently acquired by SuSE.

I think there are plenty of examples out there, but they're all enterprisey, not consumer-targeting. Consumers tend not to have sufficient requirements to make it worth purchasing support and licensed versions of anything bigger than Sublime Text. Businesses love this stuff, though, since open source allows them to fix things in-house and send patches upstream rather than having to wait for the vendor to get to it.
I think these things are important to have as tools in your life, regardless! Life can get overwhelming in all kinds of different ways; knowing how to put your head down and take care of yourself in these ways is incredibly valuable.

Unfortunately, after a while doing all the above and more, I realized my feelings towards my coworkers and company had nothing to do with burnout. Sometimes you realize everyone is miserably bad at their jobs and you don't want to keep dealing with an increasingly shitty work environment.

Another valuable thing is putting yourself in the position to be able to leave.
Also realize it'll take months to recover, not just a few weekends. Me personally I left my job 8 months ago and just starting to feel better but have more to go, but I was at an extreme case of burnout.
In response to the pharmacy link: I suffer from alpha-gal allergy and researched mRNA vaccine ingredients prior to getting the Moderna vaccine. I was perfectly fine. There's also a /r/alphagal reddit thread discussing the vaccine they got and reactions where the majority of people said the same.

Classic flu style vaccines like J&J's covid vaccine can use either a pig or chicken egg base - the pig being potentially risky for alpha-gal allergy sufferers and egg theoretically fine. I personally have just avoided the flu vaccine though may try it this year after confirming I can get the egg based one.

The other links are interesting...alpha gal and covid-19 are both very new afflictions which don't have much history of study yet. So I take that info with a grain of salt, though lets hope it leads to some breakthrough for treatment of either COVID19 or AGS.
How do you return a giant piece of metal? Do they send a truck to pick it up? Who pays for that?
Not just conceiving; _having_ a baby becomes much harder as you age. Birthing is a pretty physically stressful process for lots of women, and the following few years is a lot of very hard work. The most demanding of your life, probably.

Edit: Wanted to add, though, that _dating_ in your 30s and 40s just gets better and better. Don't worry about that. Maturity is a bonus, not a drawback.
No, but they will pay 2% more to fix something if it means 5% of customers don't write them off as "awful, unethical, big corp" and not buy stuff from them.

There are plenty of examples of companies that did or did not react to negative PR, but the effect is in the statistics, not the individual anecdata.
The Houseboat Wars of Richardson Bay
I would be put off by it as well, but good memory and cameras are harder to spot, so the lack of a notebook doesn't offer much protection.
This is meant for traveling. Countries like the Netherlands use Zero Knowlege proof based solutions for domestic use.

To exactly prevent this from happening.
I think it's a derivative of CFR, with a lot of optimizations and abstractions. They reduce the search space by grouping different card combinations together e.g. KK and QQ are treated same. They also limit the action space and only allow half-pot or full pot bets.

This is what I remember. I went through what they published briefly sometime back. So I could be wrong here.
You can do this in any language. Rust doesn't support it with PrintLn but it's still possible with Rust. Stop acting like C did anything wrong.
Does one week really resolve it or does it just restart with added pressure? Feels like they might need to pull 2 - 3 weeks to really take pressure off.
I’m not being completely serious here, but in my Facebook circles some people celebrated the tick effects unironically.
In my experience, it wasn't that people wanted to keep XP forever, it was that Vista was worse. When 7 arrived, the number of XP holdouts fell quickly.

The trouble with 7 in that situation is that either 8.1 or 10 needed to be the next good version, but they weren't. Do you know anyone who actually wants their system to change its UI every six months? Or to install updates whether they agree with them or not, even though those updates can have serious consequences if they go wrong and cause inconvenience even if they work? Or who likes having their own computer phoning home without their consent? Or having ads inserted into their daily user experience?

If Microsoft was producing an operating system people actually wanted, they wouldn't need to push dodgy updates to get people to use it.
I'll assume you're being hyperbolical. By all measurements the latest Safari, whether on the desktop or mobile device, is as "modern" a browser as any of the others.

I frequently build PWAs, and see no more friction building a PWA using Safari on iOS/iPadOS than I do for Chrome on Android.

That said, the reason the OP's site doesn't work in Safari has nothing to do with whether or not Apple supports PWAs or not.
I've had 2 friends start revenue generating MVPs on Bubble.io

One is a Cameo-like platform for LatAm, the other is a TikTok like short-form audio app .

I've been incredibly impressed by the platform and extensibility. If you have basic coding skills I think it's much more powerful than Webflow or other platforms.

https://bubble.io/showcase
The integer square root is mild a generalization of the floating point square root (in the sense that if you swap ints for floats you get the ordinary sqrt back out). With that in mind, do you think that the different name is chosen because it's a fundamentally different operation or just because of limitations in the dispatch mechanisms of common languages?
I experience multiple bouts of burnout where I said I would never code again, in fact my head hurt just looking at code. Presently, I'm writing code and launching a company.

In hindsight, for me burning out wasn't really about being tired or having carpal tunnel, it was an emotional exhaustion that was due to a complete misalignment between expectation and reality. Specifically, I was very disillusionment with what I was working on. If you're 4 years out of college, this is right around the time where many people become disillusioned. Your friends may be in the same boat, you can tell if you're seeing IG photos of your friends backpacking in Asia, launching some social impact startup, or taking a sudden interest in "authentic" activities such as baking bread. The point is, many people are experiencing the same thing.

What helped me was taking some time off from coding completely, and finding a more interest project to work on. Eventually you have to realize all stories about what tech or life could be are just that: fairy tales. You have to define your own whys and work from that. On a daily basis, what helped was to have another goal that I pursued with just as much focus, for me it is running. But the balance really helps. Meeting friends from different industry also helps, they make you see that your struggles are common, and what you're worried about is probably not worth it. Also, this might be the last time in your life where you can meet and form "real relationships" before the chill of adulthood really sets in, so treasure it.
Very curious on how this is going to work, especially advertisement-wise
I believe for the case of SaaS, at worst it's just not possible, and at best the odds of identifying and building a successful SaaS tool with no code is probably orders of magnitude lower than otherwise.

That being said there are many people who have built businesses around helping companies with setting up WordPress and Shopify sites, which are all about navigating their admin panel, dashboards, etc. You would not be the first person to help set up websites with no code.
Yeah. Rails certainly has a lot of influence over the developer experience aspects of Elixir and Phoenix. Love most of what that brought.

Jose has really thread a needle with Elixir I feel.

Rails has a strong reputation for productivity, it doesn't have the strongest reputation for long-term maintainability (though it can certainly be maintained). Or that's what I hear from the ex-Ruby devs in Elixir. I came via Python and I'd say the same of Django.
I mean, your IP is being crawled by random bots dozens of time per day, what's the difference between that website and the traffic your IP gets already?
Getting cancer helped me. Though I wouldn't recommend it. As everyone has been saying focus on Sleep, Exercise, and Nutrition. In that order. Take time off, but most of all, realize that it doesn't matter. If you show up for your standup only doing 1/8th of what you were supposed to, and your scrum master is annoyed, it doesn't matter. Even if you end up getting fired, no one is going to remember in 1000 years, give yourself a break. If you're any good, finding a new job is easy, fixing your health is not.
I think good management can turn it into a real vacation. Our teams works in scrum and we just commit to fewer or smaller tasks, accounting for the missing person-days.
> It's the iPhone of exercise equipment.

It really is.

> I know buying a good exercise bike, monitor (which they may already have), and a subscription to some cycling class service or box set isnt a sexy solution but damn is it so much cheaper.

circa 2007 you could say a similar thing about the iPhone
Odd, pretty sure it was you who misrepresented what I said in attempts to manipulate.

You were also the one who "exaggerat[ed]" my claims. I made a general statement about my thoughts about future AI-based software rather than human-coded.

I still think that's indeed the inevitable future. Doesn't seem like it's remotely outrageous or an exaggerated. I never said GameGAN would be that software, but you seem to want to make that be the case so you can put it down.

What makes you believe neural networks aren't or could not be deterministic? What makes you think NNs could not eventually produce far more robust, reliable, and secure operating systems?

Seems obvious to me, but I guess you're more informed than me :)
What isn’t clear to me is whether Peloton intends for this to be a permanent end state - that you need to buy a subscription to use “Just Run” - or if it’s a temporary state (we introduced the locking feature, made a dumb decision to require an account, and accounts are tied to paid subscriptions, and thus until we unwind that, here’s a few free months.)

The former would be absolutely reprehensible. It’s ransomware, in the name of a death caused by your product.

If it’s the latter, they absolutely blew it while communicating this.

The likely scenario to me is somewhere inbetween. They are seeing how people react to this and were intentionally ambiguous to give themselves an escape hatch if there’s backlash.
If Microsoft jumps in you can 100% count on that nonsense being bolted in addition to ACPI.
Maybe not a short vacation but enough time will do the trick.

Source: just came off a 2 1/2 year break
What are the greatest successes of causal inference? What problems have been solved by the do-calculus or potential outcomes frameworks?

I'm pretty sure the link between smoking and cancer was established before causal inference came about.
{-260:...} - why is key -260 ???, I mean who designs format like this?! Like in the middle of nowhere, bam -260. I would understand {type:-260, data:...} but this?! What is wrong with these people?
See my second paragraph. I addressed precisely that.

It is indeed what you say -- "you may capture sales that you would have otherwise lost" -- and that Amazon prefers to capture those rather than having another site capture then. Remember, people who are highly price-conscious compare sites.
Terrain probably matters a lot here. On flat ground the giraffe kicks the shit out of humans. On uneven terrain with nooks and crannies to hide in and trip up the long legged thing, and rocks to throw at it to keep it mad, I think a human would have a good chance (not a giraffe fighting expert).

Humans probably have more stamina, if you can drag out the fight.
This seems to be quick and gives decent results for what I tried! Very promising!

Going to try setting it as the default...
No, they're not. Learn some history. You'll see profiles of many people have that pathway.

You'll also see virtually everyone 300 years ago was exposed to things which would be considered traumatic today. It's how we evolved.

We've got a bad theory of trauma and resilience.
Federalism was one of many victims in the War on Drugs.
Is it likely that when we advance physics beyond all we can possibly imagine, our cloaking tech won't be material-based but powered, and some glitches will be so big that sometime, the energy distribution and the cloaking will fail?

Also, i would totally make contact with an industrial civilization that threaten to destroy most of its ecosystems before they do so, and if ET are visiting us, they are at the very least jerks. The "studying us" explanation doesn't fly, because if we are ever capable of navigating through the stars, we will be able to simulate false worlds with human who think they are biological and not simulations on them.
I'd be really shocked if it didn't tie to BAT in the Brave Browser, but I am definitely curious what they'll do for people who use it with other browsers.