skysight-inc/HackerNews huggingface dataset:
Yeah you’ll rather blow your brains out than try to understand the totality of feedback loops in our bodies. The thing with biology is that you can always try to nudge one subsystem to fix something, but then there’s the next and the next, ad infinitum.
Thing is, mitochondrial, AFAICR, has never been the main focus before. So it's still a bit useful to be able to review it for the mainstream.

That said, +1 for holistic approach.
Steps were not skipped, but they are left incomplete. None of the vaccines have left Phase 3 yet, have they? Also it’s really hard to be confident in the data collected about vaccine safety as there is a social stigma associated with claiming that you have a negative effect from the vaccine.
Well those aren't the only alternatives. Most people just turn around and get another used car again.
No, that sounds a bit excessive.

If you're growing the business at a healthy clip, maybe those sorts of raises are sustainable.
Absolutely. And actually I think is the major flaw in his argument - NFTs effectively allow you to buy a real birkin for the price of a fake!! And that WILL be exploited, probably heavily.
If I'm understanding you, you might like pgtyped: https://github.com/adelsz/pgtyped

(If you mean infer solely off of queries, I don't think that's possible unless you jam a bunch of type casts into the field selection part of the query.)
Resources were used to build the vehicle. If a car ends up in the junk yard while still drivable or economically repairable, I wouldn't consider the car to be "fully depreciated". The objective function I'm considering is emissions/deaths per mile.

The most extreme example would be a car with a catastrophic failure that will happen at 200k miles, but the owner only drives 1k miles per year. Parts will become an issue far before the useful life of the vehicle is up. The resale value would be basically 0 after 50 years because everything is so out of date, from safety features to creature comforts.
Every time you see the trope about a startup inside a big company: run.
Our park got a big disk swing. I have seen kids, girls and boys, but more girls over all, pile on and just chat and swing. It has been interesting to watch the dynamics. They really do enjoy shared experiences.
This is false. I've worked with many dealerships across different brands and the service department generally makes far more profit than the sales department. This is especially true outside of luxury brands where actual margins on new vehicle sales can be in the single digit percentages, while margins on basic recurring services are huge. See this Edmunds article for a pretty accurate breakdown [1].

[1] https://www.edmunds.com/car-buying/where-does-the-car-dealer...
Ivermectin has wide antiviral properties https://www.nature.com/articles/s41429-020-0336-z

The fact that you call it a dog medication shows that you lack a basic knowledge about the history of this drug.

Problem with vaccines is that they take time to be effective (for AZ vaccine up to 14 weeks). In addition vaccines are not 100% effective. Therefor it is definitely beneficial to have some form of cure.
a cash balance defined benefit plan or pension plan...
https://www.dedicated-db.com/ownersplus/

a floor on pay
defined roles
Same here, except for the tax stuff (I’m a Californian! Take my money!). I work maybe 30 hours a week and it’s the best retention policy I could imagine. It just means I screw around less online during work hours. I’m happier and more we’ll rounded.

I’m convinced it’s nothing but positive for most workers who aren’t constrained by the hours available for meetings, meaning ICs.
Lol at parent comment being downvoted - being overweight is absolutely a medical problem, people need to stop normalising it.
I recommend commenters don't rise to the bait of the headling ("the key" is stupid) and respond to the précis instead: "Some researchers suspect these bacterial ancestors living within our cells may contribute to a wide range of neurological and psychiatric disorders."
My DVD based navigation system is on the newest maps it will ever have .. from 2015. It'd be nice if the data & build tools became open-source after being abandoned for ten years, but it's not up to Toyota - it's up to Garmin/Kenwood/etc. that built the unit for them.
My mental model for this process is that whenever a team chooses a new language with a less-complete stdlib (eg moving Perl -> early Python) it’s because there’s a net gain for the specific task at hand, even though you take a productivity hit in some areas.

Then if enough developers use the new “better for task X,Y,Z” thing then there is incentive/resource to gradually grow the stdlib capabilities to cover all the old use cases. And in doing so, often some of the initial expressiveness/focus is lost, so there’s now a bit more room for a new focused competitor to come in and repeat the process.

Some find this exhausting, or think that it represents “fad chasing” without creating any new value, but I think it’s just what progress/evolution looks like in a community-based system of knowledge like software languages.

To your point about lisp or ada being better - using an evolutionary metaphor, it’s possible for fitter genotypes to lose to less-fit ones through random chance. But in these cases it’s hard to tell whether it’s not actually the case that these languages, while better for some users/use-cases, are actually lacking something that makes them suitable for broader usage. (For example - if a paradigm was incredibly productive, but requires you to have a maths PhD, then you’d expect to see some users claiming the tools are better, at the same time as those tools failing to get broader adoption. I’m not making a specific claim here about lisp, just painting some possible fact patterns that could explain the phenomenon.)
To be completely candid, the situation around model release is so fucked that it’s anyone’s guess.

The logic never holds up. “Ah yes, if we release our best model, then maybe someone will come build an entire business around it and out-compete us.”

OpenAI started the trend by refusing to release GPT-3. But GPT-3 makes millions, so at least they can say “hey, that’d be like giving away X million.”

It’s all so tiring and depressing. I usually have something positive to say, but my original hypothesis of “npm for ML” seems like a decade away. The culture here is starting to look alarmingly like closed-source gamedev rather than open-source unix.

“How could we possibly justify releasing our code? We wrote it. We paid N developers $X, so that would be like giving away $Y. Plus someone might take the code and build a business and out compete us…”

But I’ll never have that mindset. Subreddit simulator was the only model I never released, and it was because I forgot to check with the creator whether he’d be cool with releasing the model after I trained it. He had different concerns, but I can’t remember them clearly so I don’t want to paraphrase. But I clearly remember they were bogus in exactly the same way, just a different domain (cultural vs commercial).

But hey, at least they released “not our best model.” That’s something. It is indeed better than “no model at all.”
Hi Robert! Is it true that if I launch my i-485 application before receiving fully my OPT EAD, there is a risk that my OPT EAD will get denied (immigrant vs non immigrant intentions)? I want to get my OPT EAD as current delays for I485 EADs are around 7 months and I would need to start working before that. But I also need to launch the I-485 ASAP for my partner! Thank you
Have you spoken with the folks at https://www.4dayweek.com/? There might be a collaboration and scaling opportunity there.
Alan Turing's biggest fan remains the real enigma
Not this test. Julia’s JIT compiler does not know about runtime values, it’s not a tracing JIT like the ones you may be used to. Instead, it’s ‘just ahead of time’, compiling a specialized executable for each new function signature the first time that signature gets hit. I.e. if I do

f(x) = 2x + 1

The first time I call

f(1)

it’ll compile a function specialization for f( ::Int), and the first time you call f on that integer it’ll be slow and all the subsequent calls will be equally fast.

Next if you do

f(1.0 + 2im)

it’ll compile a new specialization for f(::Complex{Float64}) which will be slow the first time while it compiles and then fast on all the subsequent runs.

The genius of Julia’s design is that the JIT compiler is designed around the semantics of multiple dispatch, and the multiple dispatch semantics are designed around having a JIT
Having zero experience with this I could see myself getting used to the notation. The dot before the addition sign is strange looking to unfamiliar eyes, is it calling + on the result of f.(x)?
I recently had a nearly 20 year old car as my daily driver (I was original owner). Was very sad to have to let it go.

However it was a car designed and built in the days when cars were still largely analog. No infotainment, no fancy technological wizardry governing the power delivery or handling.

Nowadays many cars have gizmos and gadgets up the wazoo. Even if the base mechanical bits continue to work, wouldn't a lot of the fancy features become akin to Stone Age technology? That infotainment system that is awesome in 2021 isn't going to be so hot in 2026 let alone 2031.
Well, kind of. Apple was able to kill Cydia Impactor (which is predecessor to AltStore) without breaking their “legitimate” code signing service.

http://www.cydiaimpactor.com/
You don't get SARS-CoV-2 by combining an RaTG13 backbone with a pangolin spike in a lab -- it is still decades of evolution away form SARS-CoV-2 which you don't get via passing it through a dozen generations of mice. There's no evidence WIV was ever doing GOF research (although they did collaborate with GOF research that happened on US Soil), it is entirely circular logic. The idea that WIV employees were treated for SARS-CoV-2 is entirely evidence free, nobody knows the names of those employees, China has claimed those were 3 samples submitted in Jan from community collection which is rejected out of hand because it comes from China. The whole lab leak theory is that its a coincidence that the pandemic started in the city that had the lab, and the theory that coincidences never happen.

This is what actual science looks like:

https://www.biorxiv.org/content/10.1101/2021.01.22.427830v3

https://www.cell.com/cell/pdf/S0092-8674(21)00709-1.pdf
Maybe a nitpick but why would someone put time on Y axis? I remember it's DRYMIX for graphs - dependent on Y axis (N), independent on X axis (time)
Maybe Amazon just needs better SRE. They should read Google's SRE books.
History is not made with "if"s. Closed source alternative browsers existed, and failed. Open source and Open core browser dominated the space, and that's it.
Julia startup can easily be minutes with big libraries
When I looked at getting a new car five years ago, I found they spy on you extensively. Nope, will never buy a new car again. Unless I can find one predominantly analog.
Cool. Though I wish the installer would let me choose my own path (what's up with software installing into the horribly inaccessible path of %HOME%\AppData\Local\Programs anyway?)
ChemRxiv Re-Launched on Cambridge Open Engage
Oh, we would be using Flash and Actionscript. Much better indeed, huh? :D
What I don’t get about Amazon is that AWS customers have way less oncall load, particularly Netflix, whose engineers could afford oncall 24x7 for weeks or months with perfectly normal work-life balance. Why can’t Amazon, the pioneer of cloud computing, achieve the same level of effectiveness?
No, not at all. I’m pointing out that people fought against limiting the workweek to 40 hours but productivity ended up rising. Point being: fewer hours doesn’t mean productivity will necessarily go down. So if we’re gonna go to a four day week, why make the days longer?
Just to be clear, every vehicle sold in the US, Canada, and a number of other nations had to have front left and right airbags as of 1998. By 2009 -- 11 years later -- even the lowest cars usually had a barrage of airbags, ABS was mandatory, and so on.

So you are most certainly mistaken about the claim that it is sold "everywhere", although you have since edited that to be restricted to "where they sold them" which conveniently excludes all the places where it simply couldn't be sold.
One other thing to note about open source and I was explaining this recently to my daughter who is planning to major in CS and become a software engineer. . .

If you create a popular open source tool/framework/etc and it really takes off, that's pretty much an amazing bullet point to add to your resume. In fact, some companies might proactively seek you for that. And you can sometimes turn that into a lucrative commercial software company too. . . a la Freemium model or by offering paid support/customizations.

On my part, when I'm hiring, I don't count it against someone if they don't have open source contributions that I can use (because I also respect the right to NOT code every waking moment of your life) but if someone has built something I've heard of and even better, something that I use and value. . . that's a HUGE plus.

One last note though, someone might create lots of amazing open source tools and also be an asshole and that's not something I want on my team. Some open source folks are exceptionally arrogant fwiw.
Use snprintf with a precision specifier.
Nothing against Angular 2+ ,but I have had a horrid experience with the complexity of the framework. I do admit it was mostly my fault since I went into it blind, but coming from a more jquery/(copy paste and hope it works) mindset, I just didn't really pick up the various nuances of the framework.

But I was lucky enough to work in a different project which had React, and it somehow felt more natural to my brain (more JavaScripty I suppose). I have played around even with Svelte and other frameworks as well, but to me personally Angular always stood out as the worst. By no means my personal view on the framework dimnishes its usefulness and I know a lot of people who prefer Angular. But for me personally it wasn't the best choice.
I worked for the division of CompuServe responsible for that. I even have "Internet In a Box For Kids" still in the shrink-wrap on a shelf behind me. I keep it in case I ever need to bootstrap the Internet after a disaster.

That division had some .. uh .. interesting sales ideas. One of the ones I remember painfully was an attempt to cross-promote our sign-up disks with a heavy metal band. Disks were given out for free at concerts. The net result, to be expected, I suppose, was an impressive number of confused fans calling up support and asking when the next concert was.
But it's still a heavy thing to force other people into something. We live in quasi-democracies and a significant percentage of people feel differently than you do. There's also a significant percentage of people, me included, who are willing to respect that people have different understandings of the risks.

Lots of things harm us as a group, and we accept them. We don't, and can't, aim for zero risk.
I just wish the Julia community wasn't so invested in using UTF8 symbols in the code. I understand that for Physicists, Engineers, Mathematicians, etc it look cleaner and more familiar, but when writing code that is meant to be maintained and read over and over agains it makes a difference if that µ looks too much like a u sometimes. What's so bad about just writing mu?

Anyway, this is not a complaint about the language (which I like very much), just a dislike of the popular usage
It's a great example on how people aren't good at making decisions for themselves.
Web ads are in general incredibly cheap per impression, so while I don’t know (nor particularly care to find out) where Brave’s ad prices come from, it’s not necessarily surprising or nefarious for them to be low.
Provenance is a pretty solid emulator of many game systems but last I checked it wasn’t on the altstore
Manufacturing Plastic Moulded Products Yourself
So, Betteridge strikes again?
They refund it at their choosing. It's a total joke. You shouldn't need to provide banking information to get compensation....
Faster than Python doesn’t mean fast.
YouTube Announces $100M Fund to Pay YouTube Shorts Creators
In England the plate stays with the vehicle for the lifetime of the vehicle. Totally different in America.
A significant number of Enterprise-oriented 3rd party vendors directly support SLES with their products. It's possible with the new release of openSUSE 15.3 being a bit-clone of SLES 15sp3 that we'll see an uptick in the general FOSS world, time will tell.
Would really like to see some original pictures, blur, then the model output. Pretty impressive results but it seems like it might suffer heavily from overfitting. Or maybe that's the point.

I always come back to this article: https://petapixel.com/2020/08/17/gigapixel-ai-accidentally-a...
I sold my 96 last year with 318k miles on it. Ran perfectly.

It's around 325k now, I sold it to an acquaintance.

I ran into a local at the feed store who had one, and chatted him up. Turns out he has a whole little fleet of them. Easy to work on, run forever, cheap, and lots of spare parts around.
Not only do you have to install it but it also installs a Mail.app plugin to get some data for signing or something.
Linux is used as the primary OS for many developers, it has a market share comparable to OSX and Windows there. PopOS has made desktop Linux intuitive even for people who don't care what's running on their machine.

With Apple and Microsoft effectively abandoning their desktop OSes it's very likely that Linux will become the dominant desktop OS even among non-tech-literate users.
Seems like “not expect the manufacturing to help you, just not actively hinder you” risks a lot of “interesting” interpretations.

Is my Microwave’s manufacturer actively hindering me by sealing access to its firmware behind a wall of plastic with no external port? If it’s not, could Apple just remove the iPhone’s port, throw a wireless charger in the box, and call it a day?
The idea is that every physical device has some sort of trust root, whether well defined or not.

Traditionally this has been physical possession of the device.

The treacherous computing model is to make the trust root a key that only the manufacturer has.

I'm proposing that the trust root should be "possession of the device for X days", which doesn't privilege the manufacturer with indefinite control over something they've supposedly sold.

I don't understand what you're describing. Things like "2FA" and "notifications" aren't part of a bootloader, and therefore would have to be implemented externally. Keeping the manufacturer as part of the privileged base is still the dark ages.

FWIW the answer to the gifted trojan iPhone is to make the bootloader report the signing key that it is trusting. If you receive an iPhone from someone else and you want to assure integrity, you either plug it into another device of yours which checks the Apple signing key (possibly needing to wait X days to load it), or you bring the device to an Apple store where they do it for you.
To create an NFT you need to pay a 'gas' fee. To me the large figures paid for some pixels is an incentive to get people to create NFTs and therefore pay 'gas' fees to whoever mines those numbers.

If I owned a mining farm I'd be interested in promoting low barrier to entry artwork that creates money for me.
So what? So you spend $3000, instead of $50,000 for a new car. Not having a car payment is an amazing feeling.
When a California city gave a guaranteed income, people worked more, not less
I avoid VMs when benchmarking for the same reasons you cite. Benchmarking is difficult enough to get reproducible results without adding another variable to an already noisy process.
It caught users that use my style of dumping a ‘in line rhetorical saying’ in their posts. It’s not terrible, you’d have to laugh honestly at how predictable you are.

I’m gonna marry one of my doppelgängers.
I broke it. It says I don’t exist or have any activity. :)
Because what's measured is how how the runtime (on the Y axis) increases as the matrix size N (on the X axis) increases (i.e., you set N and measure t, rather than setting t and measuring N)
I wonder if it would work in a VM install of Mac OS?
> There is a medical revolution in the pipes having to do with metabolism and inflammation.

Could you please elaborate and perhaps link relevant literature, I've been fascinated with inflammation
Yeah that’s eighth, it’s element wise addition between the results of f.(x) and g.(y) with loop fusion.

the syntax for broadcasting a regular function is

f.(x)

but the syntax for broadcasting an infix function like +, is

x .+ y

so the dot goes at the start. I think there were some convincing reasons it ended up this way, but I forget what those reasons are. It’s just muscle memory for me at this point. You can also treat any infix function as a regular prefix one by wrapping it in parens, e.g.

(+).(x, y)
And eventually exporting them or sending them to a boneyard where they end up as bits and pieces of other cars.

The usual boneyard model these days immediately cut off the high-value parts for themselves (cat converters, rims, batteries or tires if they're newer, maybe body parts), drop it on cinder blocks for 3 months for U-pullers to take off other parts, and then crush them.

(This is why I buy mass-model Toyotas, easy to fix, always spare parts, always a buyer)
> researchers could find ways to identify malware

Perhaps OS developers should move to a validation system something like FCC has (i.e. to check for allowed electromagnetic interference) that requires analysis and certification by a third party of the driver before it gets signed and rolled-out.
I can’t pay my loans
This is literally the [Mad] Hatter’s costume (1865). <https://en.wikipedia.org/wiki/Hatter_(Alice's_Adventures_in_...>
Here’s the odd thing about this thought process. The coast guard is maintaining both personnel and equipment. With no rescues, the helicopter and crew would likely take maintenance and training flights. Why does there need to be any bill given we are supporting the capability anyway. It is part of all sorts of rescue and other services that other vessels are also using from time to time. It may prevent derelict ships from blocking shipping lanes, or rescuing sick crew from larger vessels, or identifying spilled cargo or materials.
I agree with nearly everything the professor says. Hell, it doesn't take a professor; it's not that hard. It seems very probable that there are aliens; and for most of them, it seems very improbable that they can get to us, or us to them.

I disagree with him when he proposes that (a) a civilisation founded a billion years ago might still exist; and (b) that such a billion-year-old civilisation would have overcome aging (and on a long journey, they'd have to overcome evolution too).

Further, my view is that our interest in aliens is something that has grown up in the last 200 years. Once it becomes clear to us that no aliens are close-enough to us to be reachable, or to reach us, we'll lose interest.

And we'll stop looking for their signals; we'll understand that after something in the order of 200 years of them discovering the universe, they'll have realised that there's no point in communicating with us.

My guess is that there's a pretty short window when a civilisation is interested in communicating with aliens.
Out of curiosity, and full disclosure-- as a motorcycle owner:

Why would you be okay with them being outlawed? Just because it doesn't affect you?
I never use in-car infotainment system. It's Car Play (or Android Auto?) all the way.
Yes, and if a software engineer writes a piece of software on their own time and it becomes a hit and/or gets purchased by a large company, they can make a lot of money too.

But if a writer is hired as a salary writer for a show, they're very likely to just get a salary. Same for a programmer.

Big name writers can negotiate a better deal for themselves and are a different story.