skysight-inc/HackerNews huggingface dataset:
One thing that bothers me is people who talk about "SQL databases vs. NoSQL databases." That's like framing a debate on transportation as "Cars vs. Not Cars," where "Not Cars" includes bicycles, planes, buses, subways, boats, zeppelins, etc. etc.

If you take CouchDB, Redis, MongoDB, and all the other "NoSQL" databases and compare them, the only thing they share in common is that they do not use a relational data model or SQL. The way the word "NoSQL" is used, however, implies that they are some kind of united front against SQL databases, which is not the case at all. (It's why I am not a big fan of the term.)

Just like you would not use bicycles, planes, subways, and boats for the same things, you would not use CouchDB, Redis, MongoDB, and Cassandra for the same things. If you're choosing a database just because it's "NoSQL," then you are completely missing the point.
Cool :)

Have you thought of supporting what Wordpress calls "pages"?

That way it could be used for more generic CMS tasks, having one template file for both pages and articles.
I'm not disappointed, but I was actually hoping it was a playable html5 version of this:

http://www.youtube.com/watch?v=T2OytHzZ72Y

My favorite part is when he misses the goalpost in his first pass and then goes back a second time and hits it.
I've worked at an addiction clinic. Addicts often do want to quit. Witness the success of disulfiram (Antabuse) and the numerous nicotine cessation products.

They might not All want to quit All the time, but many of them hit their bottom and look for help. The problem is that it's hard to stay sober even if you try.
Two technical things if you are really serious. Localization. Make sure you can support the 22 official languages. And you need a mobile strategy. Mos of your potential users are going to come from. When you consider that brazil had more notebook shipments than India though the population is 1/5th. By my estimation, in India the mobile phone us the Internet.
I feel like I've unleashed a monster by posting this, personally I quite like the opinionated install for Jekyll especially the code plugin / view. Will be using it for my next blog install
One could imagine the government making this mandatory for all newborns just like the many other child hood vaccines. In 20 years, you would eliminate all cocaine addicts, as anyone trying cocaine would not get high the first time.

Interesting idea, not sure how practical or ethical it is though.
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Even if the market is small if they charge several thousand dollars for the overall treatment they could potentially make billions of dollars. Specially considering that they can expand to other addictive substances like nicotine.
People don't seem to get how awesome this is. Sell it to parents. You can guarantee (for some period of time likely) that your children have an artificial tolerance for drug use w/o any ill effects.

The only implication I would want to think about more is what happens next. If all or most high schoolers had been inoculated against hard drug use, does that just mean that people would buy larger quantities? Would the market simply adjust? Would more new designer drugs enter as alternatives?
True, nevertheless, there's a big difference between being able to solve a problem ex ante and being able to explain a solution ex post.
It's a pretty common feature of a lot of languages (Python, Perl, etc) so it's really not that irregular.
What does this have that Common Lisp doesn't?
That was my first concern. Cocaine is one of the oldest anesthetics, and still used in some limited circumstances. But there are a lot of derivative drugs, e.g novocaine that nearly ever dentist uses, which are basically cocaine without the dopamine high. Would this vaccine change novocaine's effectiveness in the patient?
> If the vaccine works, the big question is: who will buy it?

Maybe people who are addicted and want to stop using?
I've not been alive for 32 years....

But still learning Emacs, I still run it in viper mode. My old habits die hard. I love to troll the other unix admins at work with vi keybindings in emacs.

I'm assuming you aren't rotating your screen under linux, xinerama isn't very robust on things like that.
Yep I agree, the problem is this vaccine cures the drug effects but not the addiction or desire for drugs.
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By 'dressed up', I mean choose a set of colors (say 3) and use them for recurring elements in your pages (titles, questions, etc). Try to use colors and white space to visually separate questions, rather than borders (ex: the legend tag uses borders).
Use colored backgrounds to give a sense of vertical space. Also, most sites have a footer, that helps give a sense of space too.

I personnaly would stay away from using yellow/blue/pink/green on the same page (at 1:00 in the video).

I can send you my email, but I don't see yours in your profile either :p
It would be wonderful if they could produce an alcohol vaccine.

I then would like to see a law mandating its use for all people who who have a DUI.

Unfortunately the quantities of the active drug in your system when you abuse alcohol is orders of magnitude higher than for nicotine or cocaine. So it could well be that your body's immune system simply gets overwhelmed. (That or there could be real health consequences from the immune reaction.)

But it would be nice if it existed.
I fully support shutting down the philosophy departments from Harvard and Yale on down. Not because philosophy is useless, pointless and impractical but because today what they teach is useless, pointless and impractical, not to mention dangerous. Everyone has and needs a philosophy -- an integrated view of the nature of reality, of truth and the basis for good and evil and the essence of being human. I strongly urge folks to read "Philosophy, Who Needs It" by Ayn Rand in which she makes the case, not for her philosophy of Objectivism, but of the importance and need for philosophy by all.
IMO philosophy can't be learned/taught by the way we do with other subjects in school. Basically, philosophy answers to your questions, but only if you are searching the answer. But in most of the cases, peoples are searching reasons and logic behind a question, which philosophy doesn't provide. Here, I am talking about the eastern philosophy, which is entirely different than the western which I am totally unknown from. Philosophy can provide you vision of life, or whatever we are upto.

P.S. Let's not kill the philosophers.

Note: I am planning to join philosophy classes in my master level, once I finish my bachelors. :)
One thing that struck me strongly when taking a Philosophy of Technology course at my university (part of a concentration in philosophy) was that these philosophers really had no understanding of the technology they were trying to discuss. They'd simply latch on to something they heard--I recall "cybernetics" was one such topic--and misconstrue a bunch of news articles about it, then publish papers at each other defending and attacking their varied misconceptions. I also found that a lot of these papers included early content devoted to explaining how philosophy is super important to science/technology--but why should we bother listening to them if they can't even get the facts right?

There can be interesting things to find in philosophy, but until they actually bother to learn more about a subject instead of running off to write a paper because they came up with a great metaphor to explain what they think a gluon is, I don't see much value in their philosophizing on actual practical/scientific things.
Great article apart from the plug for Apple - I wish it was possible to get away from hearing about them :)
The problem is that patiens on the vaccine would have higher risks of overdose because they now take so much more cocaine. Also I wonder what percentage of them would try to switch to some other drugs.
Discussions of "big pharma" aside, this seems like a classic case of treating symptoms and not causes.
If you consider that the cases likely to present for vaccination are the more serious ones, you're going to be preventing people from taking one drug. If they have a serious need they will just take a different drug. Inoculate them against all the common drugs and they'll start mixing household chemicals and then you have a dramatically worse situation (google for the effects of 'krokodil' if you have a strong stomach).
It would probably be better to help these addicts work through their problems so they don't need drugs. Leaving them unable to fill a need through conventional means just forces them down unconventional paths.

Why do we have such an obviously backwards approach to drug abuse? :(
The philosopher, quoted: Philosophy teaches you how to think, to ask questions, this is useful to society. The university should keep it.

The blogger, replying: I am unpersuaded. Philosophy does not give you answers. Oh, but it does teach you how to ask questions, that is useful to society.

The straw man, beaten: ouch.
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"Sell it to parents. You can guarantee (for some period of time likely) that your children have an artificial tolerance for drug use w/o any ill effects."

I don't understand what you're saying.
People would just shift to other drugs.

This concept is nothing new; an analogous drug that provides tolerance for heroin already exists. But heroin addicts who are forced to take methadone (as opposed to those who take it to assuage withdrawal symptoms) typically just turn to other drugs.

This drug would be useless for parents - it shouldn't be used to try and force someone else not to use cocaine, since they'll just turn to other drugs. Its only potential use case is the current drug user who wishes to stop but is afraid of the withdrawal period.
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One of the points I was trying to make was, "Africa" as an entity does not exist, save for in Western and post-colonial Pan African texts. We do not see ourselves as African, identifying primarily as one of hundreds, maybe thousands, of distinct ethnolinguistic groups - tribes, if you will. I am a Luo. I only see myself as a Kenyan when I'm outside the country. African cultures - specifically Black African cultures - tend to have strong oral traditions that do not lend themselves well to transcription using Western templates for historical writing. In my tribe, there's a legend of a man known as Lwanda Magere, who conquered nations surrounding the Luo. This would be our equivalent of Alexander the Great. My guess is you've never heard of this, or the million other similar stories from Black Africa. The Mozart's of your world exist because you developed writing or borrowed it from close by civilizations. It's all about records.

>You have to keep in mind though that Timbuktu for example didn't spring out of nothing but thanks to Muslims from the North.

This would be like calling Sicilly an Arabic city. Timbuktu grew as a center of trade within Black Africa as a result of trade with the northern Arabic and Arabized Berber states. This does not make it any less valid as an example.

PS: May not look like it, but I largely agree with you.
Absolutely. I've known parents whose kids have taken up cocaine and other hard drugs. The pattern has an inevitable up and down where the kids go through periods where they sincerely want to quit, and go through periods where they are lost to the drug.

If a vaccine like this existed, it would be easy to get addicts to use it in periods where they are trying to kick the habit. And that would (for most) end the nightmare. Unless you've been close to a family going through this, it is hard to explain how much of a difference that would make.
Or dealers will spike their injectables with it to make their addict clients all the more desperate? It's really rare to find an effective one-molecule solution to complex problems of human behavior.
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This is an opinion piece that doesn't even look at the science. The ClinicalTrials.gov entry they link to as their source only lists one peer-reviewed study, and its conclusion is this (http://www.ncbi.nlm.nih.gov/pubmed/19805702):

Attaining high (>or=43 microg/mL) IgG anticocaine antibody
levels was associated with significantly reduced cocaine
use, but only 38% of the vaccinated subjects attained
these IgG levels and they had only 2 months of adequate
cocaine blockade

That's not a stellar success. More importantly, if the Phase I trial revealed that some addicts had up to 5x the level of cocaine in their systems that's a big deal!

Cocaine doesn't just do damage to your brain. It can trigger heart attacks and death by causing the blood vessels that feed your heart to spasm and reduce blood flow. If a person under 40 walks into the ER and complains of chest pain, one of the first questions any competent doc will ask is whether they have recently used cocaine.

Apparently, they didn't see increased mortality in the small sample of people they studied -- but that doesn't mean it wouldn't kill significant numbers of people when deployed across a sizeable population.

So in summary, we have a vaccine that's immunologically ineffective on the majority of recipients, which doesn't eliminate their cocaine use (just reduces it, p=0.048), and which can cause some users to boost their cocaine ingestion to very dangerous levels, and thereby quite possibly increasing cardiac morbidity and mortality (which the vaccine producer may be found liable for).

Why aren't pharma companies lining up to produce this remarkable invention? It must be a conspiracy!!!

Edit: Fixed formatting of quote.
Thanks for this explanation. It seems you know more than any of those journalists. Let me please ask you a question that has intrigued me for a while that is not directly related to this.

There have been studies showing that individuals from two different races, for example Caucasian and West African, are usually more similar genetically to some members of the other race than to some of his own. What is meant by this? How is it possible considering that people of the same race share much more recent ancestry than people of different races? Then later you see graphs showing genetic clusters, how can there be clusters if people aren't more similar to one another for being of the same race? Did they use mixed race individuals for these studies? Are the parts of the genome that make two people look more similar to each other random parts or specific ones, what do these parts do? And finally in the global similarity section of 23andme, one can see the groups he's most related to, how is this possible?
There is an equivalent - its called Antabuse (disulfiram). It inhibits the enzyme that metabolizes ethanol, causing the bad side effects of 'Asian glow' to a more severe extent. The idea is to cause negative feedback for alcohol.

Notice by its lack of blockbuster-ness and the fact that the market for alcohol is 1000x the market for cocaine, that this "cocaine vaccine" isn't good economics.
Feedback noted.

I just added my email id to the profile. Thanks.
There are numerous, if anecdotal, stories indicating otherwise.

There are also some anecdotal stories of people now having trouble due to having multiple Google accounts.

I won't accept my invitation until 1) I know it can't bork my access to Gmail, Calendar, Docs; or 2) I can use it under a different Google account without worrying about being whacked (I don't have a detailed knowledge of these supposed events) for having "duplicate accounts".

I agree with other comments, here; unless you're one of the "beautiful geeks", historically Google support is, well, not so much.
Citation needed.

This is the first time that I've heard the claim that giving someone methadone actively causes them to go to substitutes.
I think the problem is the term NoSQL itself, originally was penned as Not Only SQL. But everyone now looks at the term with No being the actual word No in relation to SQL, as if there is some war between SQL and not...SQL. I think that alone is causing more heartburn than needed between the two camps.
when there are arguments, like in the Jeremy post, commenting about tones and formal things is a huge FAIL. It is part of the expression of everyone to use the words and tones he wishes, as long as no one is going to be offended (if you are super-sensible this is your problem). One thing I always feel as a problem is that the programming community here in HN is a bit too middle class-ish, this is annoying: you are off topic, you are not polite, respect the fact I don't understand, blablabla. Hacking is in my vision connected with cultural freedom, and not being polite is not the only but one of the possible expressions. So reply to arguments and stop to be so childish.
I've had the same problem. find and dd two *nix commands which betray the Principle of Least Surprise. I still use them, but I always find myself having to think twice before I do.

(Though you should probably always think twice before using 'destroy disk' anyway!)
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It's not a beautiful tool, it's an over-large conglomeration of functionality that already exists in the shell. We don't even have it in Plan 9; here's how you can do some of the examples I'm seeing in comments here:

To just find a file:

du -a . | grep filename

To find every file containing the string "foo" (the awk is necessary to remove file sizes, you could combine du and awk in a shell function if desired):

for (i in `{du -a . | awk '{ print $2 }'}) {
grep 'foo' $i
}

Really, the for loop above takes care of a few of find's options. Why do you need both "-exec" and "-delete"? Exec is far more versatile, you can just exec "rm" on the files. Except that as I've shown above, it's already quite easy to execute a program for every file that matches some criteria, and you don't have to learn the dozens of options used in find--you just apply the shell programming knowledge you should (hopefully) already have.
I wonder if it would bind to some percentage of naturally-occurring stimulants in some percentage of the population.

That's the kind of thing that can really can bring about the downfall of an entire civilization.
I don't know what the rules are like in India, but in America you don't have to pay taxes if your income is below a certain amount. I'm guessing that most of the people who don't know English are going to be in that lowest tax bracket.
I've usually seen Neanderthals described as Homo sapiens Neanderthalensis, meaning that they are considered the same species.
Antabuse only causes effects while you continue to take the medication. There is a world of difference between this and a treatment you take that provides prolonged resistance to alcohol.
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Did you read the end of the article? Big pharma's concern is not the market size but the PR fallout from producing a vaccine that causes some users to buy 5x more coke than they had in the past.

Why would there be enough demand for the drug to create funds from VCs and grants but nor enough demand for big pharma to do something? I have no idea about Phase 3 requirements but I imagine it is not a friendly to startups.
Yep, and it would be easy to add, but I never needed it. I don't think that's coming into fugitive itself but a few users with different needs already forked the project to adapt the hooks, not to do that though, but you could fork it to and make it manage pages (which would be like articles except that they won't go into the previous/next chain, and not in the archives or the rss feed either).

If you need some help to do it I'll be glad to help.
> I then would like to see a law mandating its use for all people who who have a DUI.

The problem is that such vaccine wouldn't only work when you are in a vehicle or prevent you from making other stupid decisions. This really wouldn't address the root cause and would be a pretty egregious violation of an individual's freedom of thought.

The idea of the state having authority to permanately biologically alter an individual to control his or her behavior is a throwback to the time of lobotomies, which even the Soviet Union banned in the 1950s.
Thanks bks - Backblaze looks like a great alternative.
Because the plugin is written by a github user, not github themselves.
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Thank you. I had the same reaction when I read the OP.
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"A Gameloft employee, who asked not to be named, said a clause in their contracts allowed for a "reasonable amount" of unpaid overtime."

And another clause most likely allows them to quit with a two weeks notice. Why don't you just quit?
There are so many t-shirts waiting to be made from this.
Thank you for pointing out OMeta, that project looks amazingly useful. Especially since it's original implementation is in JavaScript. Which means I can (fingers crossed) easily drop it into a project I'm working on...
make sure you have a valid MX record and make sure the ip you get is not in a blocked segment in the major spam lists. You might need to do some work.
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I always hated grading on work in my earlier classes because until the work started to get challenging I could do the entire problem in my head.
You are correct, I apologize for the mistake.
I'm inclined to agree, I have never taken the time to learn the various somewhat arcane switches you can pass to find (not to mention that it doesn't follow - for short -- for long switch convention).

I simply do find <path> to give me a list of all the paths under the current directory and then pipe that into grep.
Obviously this doesn't really have any bearing on points the author is making, but a small nit for posterity's sake - I think the point Clayton Christensen was making in The Innovator’s Dilemma was not that people should adopt inferior technologies to gain leverage later.

I think the point in that book was more that new technologies are often inferior in many ways to existing technologies when they first start out, and the way these new technologies survive/grow is by appealing to niches that value the existing ways in which the new technology is superior. Then, when the new technology matures a little more, the market to which it appeals grows a little larger, and this repeats.
Right now those humans would not choose to start a project in php, but a few years ago there were not too much alternatives. It's not for nothing that the world's second biggest website is written in php.
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Well, that very article laid the groundwork in the last sentence: "Variability is very important for long-term survival of a species," Labuda concluded. "Every addition to the genome can be enriching."

Basically, he's saying "hybrid vigor". Boom, there you go, supremacists, have fun!
I studied Philosophy at Reed College. The department there is biased toward the analytic side, which means I mostly studied set and number theory, reference and meaning of language, and other somewhat technical questions.

I'm absolutely certain this was better preparation for my current career (writing Erlang and making dorky music videos about CouchDB) than anything I could have learned in a CS program. Maybe other folks wouldn't be adequately prepared to be coders, by learning the basics of predicate logic and theories of naming, but it certainly worked for me.

If CS is practical, Philosophy is more practical. :)
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