skysight-inc/HackerNews huggingface dataset:
> There seems to be an assumption underlying medicine that things must be true at the population level for them to also be true at the individual level.

That really isn’t true: medicine as a field does not have this assumption, and rare disease research is a thing (and it’s commonly acknowledged that “rare diseases”, taken together, aren’t rare at all). In fact, rare disease research is providing acute clinical diagnosis and sometimes cures for highly individual cases. Personalised medicine is probably the fastest growing subfield in medical research.

Your example of antidepressants underlines this: it’s in fact widely acknowledged that, while antidepressants on average only have a very mild effect, they can be very effective (or, conversely, not effective at all) for an individual, and they are actively prescribed with this in mind. Contrary to what you’ve claimed, no expert assumes that antidepressants have a uniform effect across subpopulations.

However, treating each disease as a completely individual case just isn’t feasible at scale, and is usually also not appropriate. So the first anamnesis will always focus on common diseases, and rightly so.
Do you have some specific examples?

E.g. ripgrep is packaged on most operating systems I have used, along with exa, and a few other Rust utils I use.

I certainly do not use Cargo to install them.
> Same thing any one does with money.

Let's see.. i earn my wage with money. I pay my taxes with money. I pay everything with money. I can pay almost nothing with bitcoin and it's getting worse.

> people will still continue to use it [bitcoin] the way they currently do

They are using it for speculation and for ransomware. Seems like both of these uses will be hindered by outlawing all official exchanges.
Seems like it was a subliminal ad for Futurama then.
Ukraine hackers uncovered who targeted U.S., Korean firms, say police
Canada launches long-awaited auction of 5G spectrum
Turkey's Trendyol in talks to raise $2 bln investment -sources
That's the point, by Apple taking control of the interface and preventing dark pattern bullshit, opt in rates are way lower on iOS than on websites.
No worries, we can replicate the experience with WebAssembly now.
I’ve gotten job offers on three separate occasions off the back of side projects I was playing with between jobs, and neither was particularly impressive. The benefit of going in with a side project is that during interview you can show what you’ve been working on, and you can dig into the code. That’s not something you can typically do with things you’ve built for an employee because everything is under NDA so you can only talk in general terms.
This comment would make it into awesome-space, for me at least, if it had some examples of the issues you mention.
Americans like to believe that becoming a doctor is so much harder in the US. This is not true. I am a foreign medical grad. It is actually pretty easy to get a passing mark on your exams, and from that pov your system is not what it seems. What's hard in the US is getting into med school. But it's not that much harder than in Europe, apart from the cost of course, which acts as the major barrier in your country.

In fact, education and medical systems are different enough between Europe and the US that saying one is harder is very subjective. For instance, american specialists are really hyperspecialized. They often excel at what they do, and are completely ignorant of other fields. Europeans often have a much broader medical knowledge. They are also far less aggressive. All in all, I much prefer Europe.
I personally use zsh, bash is too primitive with regards to its user interface (line editing, searching, vi keys, etc.) The syntax however is my key point here, I often take my commands and smack them into Makefiles for example.
Analysis: Nvidia’s closing of $40 bln Arm deal could hinge on Europe
Why would this matter? Let's say a research company invented a three dimensional computer chip. It would still be a breakthrough, even if the initial samples could only run very slowly.
I think it goes without saying that you can't build a castle on a beach.

So too goes for reliability, you need foundations on which to build.
Is there a recent comparison between Alpine, Debian slim and Ubuntu core?

Preferably with some complex software installed?
Not only IBM, also Compaq and the daily hated Oracle were early contributers.
This is exactly what we're trying to do at Super Agent - check it out https://www.super-agent.com. Choose your preferences once and our extension will automate opt-in/opt-out where possible :)
The problem is not Fuchsia itself. Fuchsia is actually well developed. It's the company behind it and what it pretends to do with it that worries me!

I would prefer a combination of Genode+seL4. (but the lack the workers to move as fast as Google)

Or even [some distro]+on top of Linux + on top of seL4.

Google scares me ATM...
What's the problem with inline styles? Just curious. Trying to understand what the difference between styled components and inline styles actually is in this case.
They're using actual Q-Bits, so I would say its an actual Quantum computer. That doesn't make it any good though. Nor does it dismiss the claims of marketing hype. This is exactly that.
Found this report pertinent to HN for several reasons:

*66% of positions classified as 'anywhere jobs' within 'Computer programming, consultancy and related' in UK

*Disproportionately affects top decile earners / degree (or above) holders

Implications:

*Expansion of the remote work economy (everything from virtual collaboration apps to remittances to at-home standing desks)

*Acceleration of offshoring / globalisation within services

*Potential UK policy changes (childcare / education, building low COL areas, immigration)
Also the providers that appear to offer a even choice of accept all/reject all, except you realise that they've classified a second "legitimate interest" option for everything which the reject all doesn't cover (because that would be objecting, not rejecting)
There is truth to that, the "something else" is a different set of trade-offs for some other things that have usually been associated with FP languages.

Rust feels like the love-child of part of ocaml (for the sum types), part of C (very small runtime, ability to generate native code, interrop with C libs, etc..), part of npm (package manager integrated with tooling, large discoverable list of libraries), etc...

Borrow-checking seems a bit newer-ish - but I'm pretty sure there is an academic FP language that pionnered some of the research.

No-one is planning to give Rust the medal of best-ever-last-ever language any time soon.

And none of that is a "bad thing" (tm.)
How can I debug CI tests?
How can debug my unit tests in GitLab? I want to be able to instantly see the route cause of the error.
Is it possible to instrument tests with APM agents to see traces?
As an embedded dev I think of using it, but it depends. If it comes with any forced Google stuff or telemetry, it is disqualified before it even made an impact. Talked to other devs and most never even heard of it. This world is always a bit slower and I doubt many will jump ship quickly. The IOT craze seems to lessen a bit in recent years, devices slowly loose their image as being interesting toys.

I know that the industry likes to place themselves as an intermediary and later opens their hands. So it would really need to offer much...
From what I see (on the employer side), in most markets the way to get back into the top of the funnel is to flip every profile flag that says “actively open for new opportunities” and to respond to recruiters.

A gap where you worked on technical projects that didn’t work out business-wise will make for interesting interview slots (in a good and memorable way for the interviewers).

Three months ago may have been 2% better, but from a macro perspective, this is likely the best time in history to be looking for remote work.
Your website mentions Pull Request analytics which to me is more interesting than the Slack integration but it's light on the details.

Could you share a demo or screenshot of what kind of analytics a team gets from Axolo?
Bret Victor is our idol! I didn't even have to click the video to know exactly which one you were talking about :)
Speeding up message parsing by 3 times by switching from serde to the nom
IBM and Google are about neck-and-neck with state of the art quantum computers (both 53 qubits, each using fundamentally different technology). So yes, this one is real. However it's all research at the moment, there are no practical applications that aren't better solved on a classical computer.
My story is the same, blown off by doctors for years because, I don't know, but not being "too successful" was definitely part of it.

Lead to a burnout-like state that started developing while basically being a stay-at-home dad for a year or so. It got worse, and now there are several years of my daughter growing up that I don't remember almost anything from.
it always gave me great pause when people (even on HN) decried ECC as unnecessary, often citing Googles first servers as evidence of that.

I operated at considerably smaller scale than Google and saw enough memory errors to curl my toenails- to the point I even bought a laptop with a Xeon processor and "ECC ram" though it was exhorbitantly expensive, hard to find and doesn't have a viable successor.

And, for what it's worth, Google recanted that idea and are operating with ECC now.
The mighty English navy used to take on unarmed fishing vessels. Lethally. The Dutch first came up with the concept of international waters but it took a few centuries before everyone was on board...
Grobid: Machine learning for extracting information from scholarly documents
While NZ’s leadership choose not to name the shooter in their public statements, the name of the NZ shooter is well known. It is right there at the top of the Wikipedia article on the incident, and many non-NZ newspapers choose to name him.
Tinder, Google, Amazon, Twitter, Facebook and other plaftorms can reliably ban an account without knowing the name, surname, birthdate. Just from the broad fingerprint of the device, email, phone number, Wifi SSIDs, location, and other data they collect. Yet they are showing the cookie and "privacy" splashscreens and popups on every visit. Every. Freaking. Time. Google with Youtube in particular. Isn't it malicious compliance?
Security is expensive. Redundancy also. Unfortunately they have great savings potential.
> Adtech companies don't want users to have an easy opt-out. They didn't want P3P. They didn't want DNT. They will not want this new spec, unless the spec is so bad that most users will agree by accident.

Reminder that Internet advertising has a lot of actors with competing interests, and it is not usually the "adtech companies" who don't want users to have an easy-opt out, but publishers and to a lesser extent the advertisers. Many "adtech companies" would love to have clearer legal signals and simpler, industry-wide justification to collect less data.

Publishers have been very good at foisting all user frustration off on vague "adtech" (or alternately, adtech companies have been effective at reputation laundering for publishers/advertisers) but they're the ones that want to collect, share, and sell the data to be able to raise their rates.
Colonial theories especially when it flies in the face of observed evidence should not be trusted.

There is a strong reason to believe it is biased.

Let them produce physical evidence of cultural artifacts that predates and connects those found all accross the Indian subcontinent.

We can then discuss out of India vs Aryan invassion theory.
Another effort worth mentioning is BQN, which is a really nice solution for anyone that wants to gets started on an APL-like language. It's very much APL, but designed without a lot of the historical limitations. The documentation is really good, so please give it a try: https://mlochbaum.github.io/BQN/

Then there is GNU APL, which is a pretty close APL2 clone. Because of this, it lacks some of the new stuff in implementations such as Dyalog, but as a replacement for APL2 is does a very good job (please give the Emacs mode for it a try, just a shameless plug since I implemented that one). https://www.gnu.org/software/apl/

Of course, I have to get a second plug in, and tell people about KAP which is my array language. It's pretty close to regular APL, and comes with a graphical client to help out with the input. It has several features that to my knowledge hasn't been done in an array language, but it's still something that can only be described as experimental. But I would of course find it fun if someone wanted to spend time with it. https://github.com/lokedhs/array
As a hiring manager at a startup-ish SaaS company:

I love seeing side projects, both because

- it shows you have entrepreneurial skills (care about and able to think about more than just code)

- as well as the technical side (shows you’re able to build from scratch, probably work across the stack, etc.)

Show off as much as you can:

- leave the websites up even if the business isn’t viable. Better to be able to see and play with a side project versus just seeing a line on a resume and having no idea how significant or good it was.

- open source what you can. It can be very helpful to point to code from real projects you wrote, especially if you have a gap in employment.

Try to foster great references. Even if they aren’t recent, you will do better if you have a few raving fans.

Unless you had a lot of management experience, I suggest trying to find a job as an IC. More open roles / people seem more desperate for developers. If you’re good, it won’t matter much if you have a gap. Personally I prefer to hire ICs who have a little management experience because they tend to be better employees as well as are more likely to be someone who can eventually lead/manage with us as well.

Overall: the biggest thing is you want to show that you have been doing good technical work over the last few years versus just some unemployable person who had “projects”.

I’m hiring frontend/React and backend/Python engineers: phil@close.com
Also one needs a black magic ceremony to be able to come up with a search expression that actually works without Google jumping in and help me by rewriting it.
The author points out that you can detect this by finding keys that have an unusually high signature counter. It becomes one signal amongst many, including IP addresses, user agents, etc that are correlated with bot-like activity. You still also get to track other things such as whether the user is moving their mouse and how realistic that looks, as well as past behaviour from that user.

I guess in the edge case where you are a legitimate but very heavy user of u2f keys and you happen to share one with a batch that is being abused for bad activity... you just get shown a regular captcha and continue with your day I guess.

The design of the system will surely reduce the percentage of people that get that experience however.
40 years is a long time, so the experience will almost certainly degrade a fair bit. The notion of editions in rust makes allowances for breaking changes while still keeping backwards compatibility, I'm very curious to see whether the problems that solves outweigh the complexity in the compiler.
The Etymology of Trig Functions
The issue might be that growth used to be a pretty good proxy for wellbeing, but once the measure was established it became the target. Some dude's law, escapes my mind.
The largest and widely known example of rich, educated as well as influential is the Tata family [1] and Tata Group [2]. HN readers may be familiar with TCS (Tata Consultancy Services), Tata Motors, Tata Steel, and many other companies that are part of the Tata Group. The Tata family [1] is of Parsi origin.

Comparatively, the Tata companies are also better and more reliable than rivals when it comes to corporate governance and ethics.

[1]: https://www.wikipedia.org/wiki/Tata_family

[2]: https://www.wikipedia.org/wiki/Tata_Group
IBM versus GlobalFoundries: A Lawsuit Instead of the Power Chips Planned
I think the only "safe" auto complete it could provide with this spec is reject all. Otherwise it could just save a list of consents with unique IDs and look at your rejection list for another fingerprinting avenue.
No, it doesn’t depend on the definition. This isn’t a point of contention amongst experts. The article you cite is simply wrong (in particular, its claim about the classification of mRNA vaccines as gene therapy in Europe is categorically false), it fundamentally misunderstands how mRNA vaccines work, and it misrepresents the sources it cites supposedly in support.
What the article describes won't work in most houses as it's designed around a thermal chimney. It doesn't work with high temperatures, even at only 85 degrees it's 78 inside. They note that building is effectively unusable during heat waves and the hottest part of the day. And the article ends by noting that the problems are continuing to get worse as the temperatures increase.

AC cooling has massive advantages, there are solid reasons why every building should have heat pumps. Doing some of these techniques can reduce the load on HVAC systems, but eliminating them entirely is a bit silly.
> How would things get 21% more expensive from one day to another?

New Laws.

Is more expensive because everybody is paying a 21% more in taxes. So either the customer pays more, or the seller accepts to take a cut in their benefits to keep the price in a strategic value (below the product of his competitors)

To compensate it and survive, the startup needs now to find a way to produce the 'same' product 21% cheaper. For example, in China.

That invariably leads to your product being cloned for somebody and fake products invading your market.
Rust is far from "one of a kind". There's a similar-ish project for C at https://ziglang.org/, and to be honest, there have been 20 such projects in the past, 6000 if you count all the total failures, I just like this one.
It's just a pity that the article ended just when I was most interested :-)
What do you mean by "after they have happened"?

The changes to an updated library don't affect you until you have upgraded to that version. The whole point of semantic versioning is to allow you or package managers you use to limit which libraries to update. So, semver is to let you know of braking changes exactly before they would happen, because until you actually upgrade the library, the change hasn't happened. Surely this makes sense? Maybe we are talking past each other.
Cryptocurrency offering returns of 100% in an year
Let's hope the deal doesn't get through. How can we ever get a competition is bigger player can always just purchase smaller and grow indefinitely?

These should be a legal limit how big a company can be before it has to split into independent entities.
> For the AIs in books and TV shows, consciousness is a curse. They exhibit unpredictable, intentional behaviors, and things don’t turn out well for the humans.

Skynet notwithstanding, do I want a program to play go with and evaluate my games or one that maybe doesn't feel like playing with an unskilled player like me or tells me that I should work instead? Dumb AIs don't seem so bad.
Problem is there's a finer line between persuasion and coercion than people appreciate. Use guys with guns to sell white powder and you're a bad guy. Place chocolate at kid height at checkout and you're a business guru.
Helping people learn to code is something that we're very keen to achieve with Utopia.
Radical Acceptance
Why ask others to guess what your motivations are if you can instead tell us?

Reducing disparity within a company is surely achievable and almost inevitable.

I don’t personally believe it’s desirable in endeavors where value contributions can be heavily unevenly distributed, because it likely leads to the company being unable to employ the very top value contributors as another company can [and likely will choose to] pay them more, which is consistent with the main claims in the article.
Oh? Perhaps I need to reconsider my past trust in Rust. In retrospect it makes sense, interop. without leaking memory would be damn near impossible.

Still, I expect it to be very hard to do accidentally. In C all you need to do is have your mind blank for a moment. Which isn't that uncommon, especially if you're on crunch or something.
Naftali Bennett
I use PowerShell extensively, and there are no significant differences in the README examples. They're basically rebranded PowerShell statements.

I see minor syntax differences, for example in the comparison operators. Nothing that would it would be worth losing the .NET BCL or PowerShell's cmdlets for.
The Shady, Secret History of OnlyFans’ Billionaire Owner
As someone said: "Everyone has a testing environment. Some are lucky enough to have a completely separate production environment."
I mean, a good first step would be to start fining companies 2% of the revenue. Especially Google.
And then maybe automate the GDPR fines, because it's definitely possible to identify that a site puts up a non-compliant banner.

No need to add the threat of jail time, _especially_ if it isn't enforced.
They grew phenomenally...

what does that have to do with trying to guess when the next paper might come out? I was just guessing what the publishing timeline might be :-P
We should strive to take jthedisciple’s comments at face value, and literally. From there we will arrive at a charitable interpretation.

Here is an example where Harvard Stem Cell Institute discusses mRNA therapy as gene therapy: https://hsci.harvard.edu/translation/what-are-drugs-4-gene-t...

The Wikipedia entry on gene therapy discusses mRNA therapy under the Non-viral section: https://en.wikipedia.org/wiki/Gene_therapy – “BioNTech, Moderna Therapeutics and CureVac focus on delivery of mRNA payloads, which are necessarily non-viral delivery problems.”

Indeed the mRNA vaccines carry a genetic payload – a segment of viral genome which is modified using a genetic perspective and from a position of genomic understanding. mRNA is a temporary and deliberately non-permanent message carrier substrate; Here too, humanity’s employment of such facts can be interpreted as scientific knowledge of the matters of the genes. If we choose to call mRNA vaccines gene therapy – which they are less clearly than other techniques – then it is certainly the better gene therapy for purposefully avoiding permanent alteration of the genome in the subject to be treated.
No, the vast majority of Android phone owners are not going to open the command line. The very prospect of it will daunt them, or it may even be unfamiliar to them (a lot of Android users, especially in the developing world, rarely or never use a traditional computer and are unfamiliar with the full range of its features). Even those users who would copy and paste into the terminal are a niche more comparable to us here than the average phone owner.

Yes, of course sideloading may still remain possible in such a scenario, but it would not be mainstream enough to sustain any kind of mainstream ecosystem of apps outside of the Google Play Store. Even F-Droid supporters have been worried that clamping down on sideloading could marginalize F-Droid even further than it already is.
This isn't technically subliminal advertising though. Subliminal ads are just brief flashes that you're unaware of consciously, but still register on a subconscious level. If the consumer was awake presumably they'd be acutely aware of an advert playing because they'd hear it. The 'trick' is that the ad is played at when the person is asleep - other than that it's a normal (although presumably quiet) advert. It seems current laws would stop that.
All murderers, for example, are “desperate” people that “had to” kill? Nothing is ever anyone’s fault, just broken systems all the way down?
Consciousness is defined badly enough that you could equally well argue that we already have achieved it or we never will.