skysight-inc/HackerNews huggingface dataset:
It's a concerning precedent. These rights to travel, to enter a store and so on were never restricted before but now they may be.

What about me, should I risk shot number two now that I've seen a flame heme show up on a routine retina scan just yesterday and am reading that this is one of the things they are seeing increase from the AZ vaccine? Will I be limited in travel and employment if I don't?
I ended up looking into Github Pages and it wasn't too hard to use. (The documentation makes it look harder that it actually is.)

Thank you, benjaminsuch, for that pointer.
It seems that according to these papers, if there was vaccine mRNA in the reproductive tract immediately prior to or immediately after fertilization, then theoretically the spike protein could possibly get integrated into the offspring’s genome. But how could the vaccine mRNA end up in the reproductive tract? Seems unlikely. It’s intramuscular, not in a vein. The implications of sperm-mediated reverse transcription are quite unsavory regardless.
Just saw this "Build Mail app extensions"
https://developer.apple.com/videos/play/wwdc2021/10168/
Does this mean we will get content blocker for email then?
The "magic" from vaccinations comes from vaccinating most of the population so that the epidemic fizzles out. In that scenario it doesn't matter that much whether you personally are vaccinated or not. An unvaccinated person benefits from herd immunity like a vaccinated person does.

From the viewpoint of a healthy young person, the risk/reward ratio of taking a vaccine is bad.
> Would you give alpha version to people you love?

If the alternative is a O(1%) chance of dying from the disease? You'd better believe I would (and did).
Way to bury the lede. You got banned for posting an offensive slurish meme in the middle of a conversation that you self-admittedly interjected into in order to compare two people of the same gender loving each other to murder.

Yes, you're such a victim, a key part of the usual formula.

Slow clap for the mods. Let this guy parrot his low-key right wing shit on this website, but the second someone calls out the usual bullshit for what it is, it gets flagged.
Apologies, I meant the CanSino vaccine. Russia's Sputnik vaccine also utilizes adenovirus and I regard Russia as having one of the world's finest medical institutions.
> Google Translate is state of the art

For French/English/German, DeepL is much better IME.
The redefinition of "literally" to mean "not literally" is an abomination and should not be tacitly accepted.
What it boils down to is the following:

1. Cells contain different organelles that serve different functions.

2. One of the organelles is the Ribosome which exists outside of the nucleus (which contains and protects your DNA) and receives mRNA and tRNA inputs and outputs proteins.

3. The mRNA vaccines contain the RNA necessary for the ribosomes in your cells to manufacture the spike proteins of the virus. The spike proteins are treated as if they were the real deal because your body doesn’t know it is hollow, only that it must be a threat because it doesn’t belong. SARS-CoV-2 shows up with the same spike protein and runs smack dab into the middle of all the antibodies your body produced to target that specific type of threat with that specific spike protein having gone through a dry run before and SARS-CoV-2 gets slaughtered for its efforts.
Isn’t it already extremely difficult to know whether you’re committing a felony by paying a ransom? You’re sending millions of dollars in bitcoins to an unidentified group of known felons; if they are (or are affiliated with) a group dedicated to the violent overthrow of a government, then congratulations, you’ve just provided material support to a terrorist organization.

The US Treasury Office of Foreign Assets Control specifically warns about the legal risk you take by paying a ransom here: https://home.treasury.gov/system/files/126/ofac_ransomware_a...
This reminds me a lot about the goals behind the center for humane technology, and their amazing podcast https://www.humanetech.com/.

They also are the ones behind the Netflix documentary « the social dilemma ».
Simple: send a letter every month with a link that says “Click here if you still want to receive this newsletter”. Then remove everyone from the list who hadn’t clicked it after a week.
It should have been you are banned / strike one for being off topic.

Linux is not about vaccines either way.

All this off topic garden shed stuff needs to be shutdown in open source. And normal companies too if they want to prosper.
I’m trying to understand why this is better than a usb WiFi dongle, and coming up empty. Anyone have an idea?
Sure, I will trust doctor Linus with this. And by the way, this email has been penned by a certain Enrico. After needless lockdowns and masks mandates you still think many millions of better educated people than this guy. There’s a shot for you… mine
Natural mRNA sequences tend to contain uracil, which the immune system is not a fan of (https://www.sciencedirect.com/science/article/pii/S152500161...). The innate immune system generally attacks extracellular mRNA because of this. The mRNA in vaccines are specially modified to bypass the immune system and be taken into cells, at which point they will be translated into spike proteins and be expressed on the cell’s surface. In conjunction with an adjuvant, the immune system will recognize this as a threat and begin producing antibodies.

It’s certainly possible that mRNAs could do harm: they could code for protein sequences that might disrupt cellular function, increase cancer risk (e.g. by disrupting DNA repair or even causing mutations), etc. The spike protein is none of these things - it just gets expressed on the cell’s surface - so the risk from the vaccine is low. And, crucially, once the mRNA runs out, no more protein will be produced: mRNAs are degraded after protein translation. This serves to generally limit the amount of lasting impact that an mRNA vaccine could possibly have.
It's being introduced to countries where such measures are new and it's being used within borders. The idea is that venue operators for concerts and other events will be checking your vaccination status.

I find that Black Mirror level dystopian personally.
Apple is very explicitly in the tracking and ad targeting business. See https://support.apple.com/en-us/HT205223 for the information they collect in order to allow ad targeting against you. They unfortunately don't explain just what the data they "make available" to "strategic partners" is though.

Note: I'm not claiming that Apple is somehow a particularly bad actor in that regard. But their ads are not just keyword based. They track you, and sell access to you based on the information they collected, just like other adtech companies. Does that change your conclusions?
Gee, I don’t know, maybe trying to hold China accountable in hopes that they stop torturing and exterminating a sub-culture of their population… because it’s wrong?
I think when people say processed food they are referring more Doritos than canned corn.
Mostly the problem isn't the processed food but the sheer density of calories.

It's quite hard to eat 3500 calories of steak.

It's really easy to eat 3500 calories of snack chips.
I like just getting up and leaving without saying anything as soon as I realize someone's position on this, even if there is social obligations involved. It's a good way to send a signal without any real drama and these people are arrogant and grating to be around anyways
Just because a food came from a vegetable does not mean that it still retains the same nutrition. Corn syrup does not have the same value as corn, just as the first most obvious example. Nobody is worried about their source material "by weight". People are worried about whether there is any actual nutrition value in the food.
Thanks for your work on BQN Marshall. Can it run on the desktop though? I know little about JS, but kind of assume it needs a browser? My only experience with JS on the desktop is via bloated electron apps. I always thought a single file
executable would be best. Is that possible?
"Bonjours" doesn't exist, and "salutations" is a tad quirky, but OK in informal settings, especially when addressing many people at once.
I mean, I guess my follow up question is... where does the reverse transcriptase come from? My understanding is that the mRNA, by itself, isn't a retrovirus capable of integrating itself with your DNA. It's not built for it. There's no mechanism for reverse transcription in the mRNA in the vaccines, and the mRNA doesn't go near the nucleus of the cell, instead swimming around in the cytosol until a ribosome picks it up.
The author is a business owner with employees.
Deciding to get infected is not "to each their own". You will statistically get someone else sick and they might fare much worse than you. Be aware that you are not only deciding for yourself, but for others as well.
> The process is very complicated and beautiful

And all the molecular machinery in our body is much more complex than any software system.
Here's the list of excipients in the Pfizer vaccine:

1. ALC-0312
2. ALC-0159
3. 1,2-Distearoyl-sn-glycero-3-phosphocholine
4. cholesterol
5. potassium dihydrogen phosphate
6. sodium chloride
7. disodium hydrogen phosphate dihydrate
8. sucrose
9. water

The first four are various lipids, used to build the lipid nanoparticles. The body can get rid of those the same way that it would get rid any other lipid.

The remaining excepients are just some salts and sugar.

Source: https://assets.publishing.service.gov.uk/government/uploads/...
Modern dogs are so far from what they were bred for, the dominant influence by far is the influence of the owners. The only relevant statistic would be: percent of bites by dogs that are owned by humans who have not properly trained the dog. That will be a statistics that is more than trivia, the charts in that article are useless trivia paid for by tax dollars.

A useful study would be able to provide a recommended course of action an owner could take to reduce the likelihood their dog bites, which is what my proposed study above would do. TRAIN YOUR DOGS PEOPLE.
This is absolutely correct. Because you can connect Apple Mail to non-Apple servers, they are missing out on a lot of telemetry that Gmail gets by default (because it already goes through Gmail's servers.) This gives them an excuse to proxy non-Apple email. (on another note, it sure seems like most of Apple's moves are dual-purpose now, and I don't think that was the case in the days of Jobs.)

However, I'd like to see the Privacy Policy (if it's available and in plain English) for this feature before concluding that they're not immediately discarding this data (or even just where I get my mail from, which is also very useful information to further lock me in.)
A few more thoughts from my 2c coming based on my experience writing a lot of code in Elixir:

1 - avoid if else {} blocks, use `cond do .. end` blocks instead, they're more readable

2 - avoid importing modules, but rather use them directly wherever possible, this will help when refactoring code or to find all occurrences of a particular Module.method()

3 - when specifying keyword list options, explicitly supply [ ] in the arguments, example: Abc.method(a: 2, b: 3) may be clearly written as Abc.method([a: 2, b: 3]) so we always know it uses a keyword list and not map

4 - Use a file `.iex.exs` to specify all your aliases and macros you may need in your Elixir shell.
Helps a lot while you're playgrounding in the IEx shell. In my case, I have aliased all my Context modules and Model modules

5 - Pattern match everywhere. This is one of the powers of this language. Make your methods follow the {:ok, data} or {:error, message} pattern and it's already very maintainable.
What? But I just put some references here: https://news.ycombinator.com/item?id=27466738

Those are peer-reviewed published papers ... and you chose to ignore them? Laughable.
Have we watched the same Linus for the past few decades?

This is very tame, all things considered, and he does take the time to try and educate the individual on the matter. I for one appreciate him doing this.
Quarterly (or less often) is every 3 months. And at least all the senior people I work with already travel a lot more often that that under normal circumstances.

People can and should absolutely pick the jobs that work for them. And that may include positions where you go into an office daily and rarely travel. But, traveling to an off/on-site every few months for a work week is probably one of the costs you pay if you want to be remote.

If you want a position that is 100% remote that never requires you to physically leave your home, you're welcome to look for such. But don't expect a lot of options at a well-paying tech job. Unless you can do something as a remote consultant.
> fast translates to vite in French

Only as an adverb, it should be "rapide" otherwise.
yet another example of the steaming pile of shit that is the social media culture...
Technically the cells manufacture the spike protein and your body will develop neutralizing antibodies to the spike protein, the cells will also display the antigen (spike protein) on the surface of the cells in an MHC-antigen complex. That'll trigger CD4+ and CD8+ T-cells to also go into action. Some of the cells will be transported to lymph nodes and the gut for processing by the immune system. CD8+ cells will learn to recognize the MHC-antigen on the surface of cells and kills the "infected" cells.

Then next time around B-cells and T-cells are primed from all this target practice and its a lot easier, even if the neutralizing antibodies wane.
Chrome abandons 'simplified domain experiment' in omnibar
That feels like a stretch to me. Your statement is a bit like saying a big bag of labelled images edits the ‘code’ of a [neural network] computer program to make it recognise images. But everyday speech means something different by ‘editing code’. The genetic material of the B-cells, used to generate antibodies, does not come from the vaccine which contains genetic material used to generate antigens.
I think part of the problem is that the science keeps changing as we find out more. Were masks going to help with Covid? No, then yes, then kind of drifting back toward maybe no.

Are RNA vaccines going to work without having many side effects? From what we know now, yes. We may learn something from trying it large-scale, though. (Just today there was this article on HN about men suffering unexpected levels of heart complications.)

This leads to people who are "pro science" but have out-dated science. And many people, even those who want to "follow the science", have run out of time and energy to keep following the science. So they treat "science" as frozen in time, not as a process.

And then you have people with vested interests and/or political angles. That includes the vaccine makers, and at times may include the CDC.

All in all, sorting out the science has become a real bear on this particular issue. People get tired, and freeze at the position the science supported when they gave up tracking.
Show HN: My daily podcast about side projects
I write elixir full-time at a fintech startup and I can confidently say that this blog is clearly written by someone with significant experience. With statements are key to nailing a balance of error handling and pattern matching, however for trivial functional flows (that don't require error handling), pipes are entirely fine.

The biggest challenges for elixir currently are the lack of established HTTP libs with dynamic testing and db ORMs. For instance, interacting with PSQL is fine using ecto, but using a document based DB or something like Neo4J is an absolute headache. Deployment is also pretty easy, but that's a whole different side of development.
> There are a LOT of anti-vaxxers who disingenuously couch their advocacy as "I'm only asking questions".

And they quickly reveal their bad faith, at which point they can safely be ignored.

Or, if you don't feel like discussing it, it's easy enough to say "I don't know about that, but the anti-vaccine stuff sounds like lies to scare people so I decided to trust my doctor."

If honest questions are met with hostility, while the anti-vaxxers are friendly and "helpful", guess who's going to be more influential?
What would a defensive NSA look like? I picture them openly accessing all US networks claiming they were "boosting defense" rather than secretly infiltrating them.
Do you think that in my decade or so of experience in losing about half my body weight, I never thought to try changing my diet?

It is very irksome to me when people try to hand out nutrition advice on the internet like they know goddamned anything about it. I successfully lost over 150lbs and I never found a solution to not craving food constantly.
I don't know much about Linux, but if you are too quick to say something off topic cannot be discussed at all and even trying to discuss it is a bannable offense, that tends to kill conversation and interfere with getting people to participate, to get along well enough to get things done, etc.
Is it fair to say vaccines rewrite it, though? It's more like your immune system rewriting it in response to the vaccine.

It's like saying a virus rewrites antivirus programs. Yes, the databases get updated for every new virus, but it's not the virus doing that directly.
It is bullshit. It helps to create an atmosphere where you can't ask questions or debate.

I'm entirely pro-vaccines. However, I'm simultaneously entirely in favor of people asking questions, no matter what their intentions are. Their intentions do not matter. You either know your stuff or you do not. It's always better to draw out the eg anti-vaccine types. If something is defensible, then don't be a coward about it, don't be lazy, respond with a decent answer. Put in some effort. Use it as an exercise for your own brain, your own beliefs, your own ability to discuss and debate in an (ideally) civil society. Only the anti-vaccine arguments benefit from not doing that.

The shut-down angle always comes from cowardice and or intellectual weakness. You can tell a lot about someone by whether they're terrified of a discussion. Shut-down attempts are meant to evade personal shame (and more rarely to avoid putting in the time/effort), while preserving an intellectual or moral foundation established by someone else who did put in the effort.

Nearly all shut-down attempts come from weakness. If the position is important, such as vaccines, then that weakness only encourages the skeptics even more. They can practically sense it. The right thing to do is to engage and push back with facts (and or even links, with which all the hidden passive readers can go make up their own minds as to whether they agree or not), even if you don't have all day to argue a topic.
I'm bridging for an IPTV box now TP-Link Archer C20i that cots me $10.

It also make 2nd AP connected wireless to first one for extending WiFi coverage. Not a perfect setup but works few months without issues.
>> prevents serious illness and death

> Only in 60+ patients with co-morbidity.

That's false. See [1] for data on deaths by age in the US. There's about 115,000 deaths in the age groups < 65 as of May 2021.

[1] https://www.statista.com/statistics/1191568/reported-deaths-...
In the 1930s you would have a wood burning stove for heat and, if you were outside of a city, possibly limited or no electricity. Almost certainly no phone or a party line.

You can get those utility costs down by living right. :)
See my other comment but basically we need to know what percent of those dog bites were done by dogs owned by people who didn't socialize and train the dogs. That would be an actionable statistical analysis.
No way. We need nearly everyone to get the vaccine, with the abstainers purely randomly distributed, in order to reach herd immunity, which we aren't going to reach, so it's going to keep spreading endemically, indefinitely. If you aren't vaccinated, you will inevitably get it, if not this winter, than the next, or the next.

Even for healthy young people, the risk of the vaccine is orders and orders of magnitude less than the risk of the virus. This is true almost by construction, because it's strictly less spike protein.
>we presume it won't happen but there's not enough and definite evidence for that.

What evidence are you looking for here? Any specific analytical protocol that you have in mind? I am curious to know what you're referring to.

As you know, the body doesn't just tolerate foreign mRNA like that (TLR3, TLR8 activation, RIG-I etc, microrna silencing, etc). So ironically, the vaccine has to first defeat our body's immune response, and then let the immune response work so that we get protected. That being said, the mRNA in the vaccine is structurally different from naturally occurring mRNA in that its been carefully engineered as a delivery platform. I am not intimately familiar with the studies you link to, but we can't just form a causal link because "its rRNA" - you need to evaluate it a bit more in the appropriate context.
Exactly. I remember when the cruise control vacuum actuated cable snapped on my Honda Civic. No more cruise control for me and I could hear the reason why!
Yeah, the consequence of large intelligence differentials in war is that the lower intelligence doesnt even know they are at war

It's not that they don't know the rules, it's that they don't even know they are playing.
None of this is correct. Both of these drugs were part of the conversation long before a vaccine was available, and at least withe Ivermectin the proposed usage is as a prophylactic or as soon as you see any symptoms. Not once you are so sick that you need to go to the hospital. To be clear, I'm not giving any medical advice, just clearing up some incorrect statements.
True but no one can secure anything. Therefore, the last thing I want is a network enabled car.

I have my phone for that.
This is fun! I wanted to do something similar but ended up buying two TP-Link AC routers with WDS for ~100$. Setup was simple and I get the full 400Mbps download speed from the paired router (the one that isn't connected to WAN).
4 billion years is a very, very, very long time.
‘We’re Going to Publish’: An Oral History of The Pentagon Papers
No, it literally returns you the first one. If you have a keyword list and use get your not going to be getting the benefit of duplicate keys.
If you are interested, we can break down what you typically eat during the day and help find out what causes you to feel that way - I'm far from an expert but there a lot of common things I used to eat that made me hungry all the time.
Could always try AES-Adiantum for storage encryption.
https://www.raspberrypi.org/forums/viewtopic.php?t=275542
"He who has eyes to see, let him see, and he who has ears to hear, let him hear."
I’m mid-career, work at FANG, and that is close to my salary. Perhaps my situation isn’t the norm because I moved into FANG from a very specialized job and got downleveled. But the point is that even within FANG, not everyone is pulling in $400k+.

The 3x income seems meaningless if I’m reading correctly. You ended up with 2x for a smaller house and yard, which to be fair is a reasonable tradeoff.
I'm going for a similar visualization with my "year-in-pixels" project aimed primarily at spotting trends in mood and/or health symptoms, but I wanted it to be adaptable. Hence the name: https://howsyourblank.com