skysight-inc/HackerNews huggingface dataset:
I have been watching and paying attention to Alzheimer's research my entire life and it's depressing how obvious it has become that amyloid beta plaques are not the fundamental cause of cognitive decline and treating them should not be the target of therapy... and yet...

I know 'big medicine' is the target of liberal and conservative critics alike, but it really does seem like once the medical community gets their reputations sucked into a bad theory it will take a good 40 years to change direction. I know good science is being done too, I just wish that we hadn't started a depth-first search decades ago.

There is real promise in the various inflammation-based theories. This drug seems like a big distraction.
I have been testing a large number of DoH servers. I have noticed that some names are not available across all (supposedly unfiltered) DoH servers. For example, there are some DoH servers that had no A record for webshare.io, the domain mentioned in the OP.
bingo - chat interruptions are more manageable than a literal drive-by
FIPS Software on Android
What is FIPS software on Android devices? Google and Samsung acted weird about it when I asked.
Yes-ish?

So the extension itself is basically a bundle of web resources like HTML, CSS, and JS files. Today, the only way an extension can ask Chrome to automatically inject a content script on a page is to declare what scripts should be injected on which sites in the extension's manifest. For example…

"content_scripts": [
{
"matches": ["*://*.nytimes.com/*"],
"js": ["content-script.js"],
"run_at": ["document_start"]
}
],

This snippet from a manifest file will inject a file in the extensin's bundle called "content-script.js" onto all New York Times web pages the user visits right as the page start loading. The downside to this approach is that this is a static declaration; after the extension is installed it can't say "hey Chrome, I also you want you to inject that same script on BBC websites.

In the quote you highlighted, what I was trying to say was that we are also planning to give extensions the ability to modify the set of content scripts while the extension is running. This means the extension will be able to ask Chrome to automatically inject the same script on BBC websites.
The brain isn’t supposed to change this much
Even so, normal people can and do buy property in close proximity to the city center all the time, and cheap rent spots are easy to come by. Minato-ku was definitely crazy overspeculated, but go 15 minutes away by train and you get an order of magnitude cheaper housing.
New SwiftUI Features for iOS 15
Give libreddit a shot. I recently switched from old.reddit.com and much prefer it.
The guide to SaaS pricing models
> It's strange maybe I like to use the mental landscape, but I prefer the ASCII character graphics than use any tileset.

The ascii graphics are vastly superior purely in terms of the amount of information you can display on the screen at once. Tiles are huge and fat, which prevents you from being able to see anything. Expect to die frequently to attacks from monsters that can't be shown onscreen.

"Modern" ToME tries to work around this by having a graphical tile be much larger than the space alloted to it on the ground. Thus, you get overlapping graphics that are very difficult to understand.

I'm not sure what the appeal of the tiles is supposed to be. The downsides are enormous.
Immunity from infection does more than the spike protein, so it ought to be more robust against variants, even if one does show up that changes the spike protein enough to escape vaccines.
Express this dismay to them, in a honest open conversation. Discover what holds them back. Be open, don't scold, maybe they reveal a problem in your attitude as well.
one of the other long term effects of covid transmission, is the opportunities given for variation and selection according to viral efficiency, in effect each infection is a crap shoot toward generation of recombinants, or molecular variants
Which means you need to find a new employer. There are companies and/or managers out there that don’t have these misalign incentives, encourage best practices (like those in this blog post), and provide psychological safety. They exist.
I know.
That was the joke. :shrug:
That is still a lot. If you do a lot of driving.
> I'm very curious how a system could be re-designed to tax people when the value of something like a stock increases, but is not sold.

If banks can use the increase as collateral on a loan, it stands to reason that the same increase could be similarly used as a collateral tax lien. (Lay opinion - entirely possible this is wrong)
Scholarships
Anyone know of any scholarships or grants for a 41 year-old woman to go to school for IT. I want to specialize in cyber security.
To be fair, If the CEO tells me “We are a family”, I won’t believe it either
Your best defence are your capabilities. Being “indispensable” means nothing if the company goes under.
Most of the groups I’m aware of use some variation on Kelly (e.g. half Kelly), but it’s worth pointing out that in some sports it’s actually quite hard to deploy your full bankroll at any one time anyway.
Phishing for AWS credentials via AWS SSO device code authentication
This! It’s generally a good idea to have a lot of smaller “dumb” views that are stateless and depend on their parameters, and a few “intelligent” views that bring the children together and provide state logic. That puts reasonable boundaries between the view and business logic, even in declarative code like SwiftUI.

I’m not a Swift or SwiftUI expert, but have written declarative UI quite a bit. Don’t imagine some base best practices would differ too much.
> No, you just make yourself disposable.

Yeah, I agree, but I think you are also meant to prepare yourself for a new or higher role in the company.

Looking at the list of what you are supposed to be achieving, it looks like the itinerary of what a manager would want from their perfect employee.
Well, the spirit of quitting might apply here too - I've worked in environments exactly like yours, and I've worked in environments where I felt like everyone on the team put in their all or even that I was the dimmest man in the room (in a good way).

The quality of life on teams like that can make slightly lower pays even worth while, so always consider that your current experience isn't necessarily what all horizons look like.

Though sometimes frank conversation can build your team up better.
I was pretty underwhelming as well. The jokes in the comments here were much funnier.

The first one from the "article" I really liked was:

New engineer: "How do you estimate how long a project will take?"

Seasoned engineer: "I add up the time required for each task, then multiply the sum by pi."

New engineer: "Why pi?"

Seasoned engineer: "It ensures that all my budgets are irrational."
We're fans of Retool, but definitely agree the requirements for internal and external use cases are quite different.

We already support CSV downloads from tables, so no worries there. We're excited to chat with your engineer and give them an in depth tour of Explo. Please have them reach out to founders@ or sign up for a demo on our landing page!
Creative concept in the domain of DevOps is found at Garnet. I have easily configured my API. The experts deeply explained things really well. Being provided the things on single sign-on has reducing the developer efforts. Multiple instance creation for single user is much appreciated. Moreover, I would recommend to all developers to must taste the flavor of garnet.
You'd be surprised at how easily they can run into each other, or have overlapping social circles. It's a drama risk. Different cities that are hours apart is a "good enough" risk mitigation compromise short of dating women in different countries and flying them (or yourself) around regularly.
Obviously it is much easier for them to have you read the documentation so they don't have to.

Once documentation becomes longer than a page or two, most people's brains shut down and go into TL;DR mode.
Sounds like you're writing from the perspective of an employee. The advice is a lot more applicable if you read it from the perspective of a founder — one who might want to get off the rocketship they've built at some point, without causing it to blow up (and tanking the value of their equity.)
Judging by the comments following this advice will get 50% of folks fired and 50% promoted.
Just use ultra thin gray font on gray background and huge padding everywhere.
Quite often the high cost of firing someone is exactly the reason why the company wants to fire them. If you're someone who doesn't do things the way the company would like that isn't leverage; that's a reason to push you out.
I had a pretty strong visceral reaction to this article.

prob because i just read about the 1%ers avoiding paying taxes, and a thousand other much-more-horrific things, only to see the top post on HN advocating for workers to make themselves even more dispensable that they/we already are -- and i don't think it was meant as a joke. :-D

i've always done the 'obsolete yourself' routine, and still do/am -- part of it was/is always self-interest (not advancement, but getting freed from having to do stupid shit), but part of it was/is 'just doing the right thing by the company' and thereby hopefully being part of a successful operation which, if you're not doing anything too evil, would allow me to take some pride in it.

but i know that many of my improvements to products/documentation/training/etc. only help offshore myself _and_ all my co-workers, especially those of us in the US and other expensive places (and we don't even get health insurance).

if i was part of some type of co-op, all that would be taken care of.

one can dream!
Manifest V3 does not currently support user script managers, but we are planning to address that gap in the coming months.
I haven't read your documentation so I don't know, but possible explanations:

1) Your documentation might be long-winded and they want a guided tour or executive summary, or at least a 10,000 foot view from which to start

2) Maybe they don't know where to look for what they're looking for; if you've documented a bunch of functions but provided no curated guide for what code exists and where to look based on a use-case, it might never be found
Okay, I think we're on the same page. I misinterpreted your original post as denying C existed, and therefore trying to set up a dilemma for people in column C (both) where they had to pick either poor richer or rich poorer. I find that most people want the poor to become richer, but whether to make the rich poorer or not is a pretty debated point.
Almost all of this could be achieved via third party apps if the screen time data was available via an API and background app mode. I understand why it's not though as it's a lot of personal data. However Apple does provide access to health data via the HealthKit so maybe they can do something similar for Screen time?

Did they make any API changes in iOS 15 announced yesterday?
I don't disagree with you. If the question was about design decisions I'd made, I'd be in full agreement. But the article quite literally says 'every time.' You could rightly say I'm being pedantic, but if you're going to write life advice, it should be quite specific IMO. I'm not trying to be a jerk, but rightly (also IMO) pointing out flaws with the wording and tone.
I have personally done it to fend on a project manager or two or to make sure that I don't misunderstand anything with a deadline someone is hounding me for.

For some reason "I am meeting with X to address it" sounds better than "I am reading Y to address it." Not sure why. Just something I have noticed.

So in my case it is office politics.

Reading documentation/writing documentation is not considered quite as productive work.
> Chief engineer: You told me that you would finish the layout in three days.
Engineer: Sure, but not threeconsecutive days!

Putting aside the humour for a moment, this is actually pretty good.
If you want to learn it from the basics and retain what you learn, the best source is probably https://quantum.country/
Making a pipe leak tight to hydrogen versus leak tight to oil is not even playing in the same ballpark. Hydrogen leaks through practically everything, oil is viscous.

Plus hydrogen burns much more easily and the flame is transparent.
Types of Sampling Techniques (Visuals and Code)
This helped me a lot and I think it made the rounds on hackernews a while back as well. https://quantum.country/

There's also this video which walks through how quantum computers solve a very specific factoring problem (Shor's Algorithm) in a way that classical computers cannot. https://www.youtube.com/watch?v=lvTqbM5Dq4Q
Every SV company I've ever worked for has explicitly disclaimed rights to my work done off hours with my own equipment... as they are required to do under CA law.
Ok, essentially you’re saying the real number of cases is higher than the official numbers reported, because the official numbers only report ones confirmed by tests, and there are many people who got Covid and were never tested.

I think most on HN would agree with your assessment that the real number of cases are somewhat higher than the official count, although I haven’t seen any evidence indicating exactly how much higher or lower. The Dakota states did seem to taper off cases immensely before the vaccines were distributed, indicating a possible early herd immunity.
> Not sure why the author put this in, but "Always be learning"

The point of the article is that by increasing team productivity to reduce your own tasks, you now have the chance to learn new things and grow into new roles as opposed to being stuck with the same responsibilities.
> I'm not sure that's the right trade off here, especially when it comes to safety and environment.

Can you give some reasons why you think that?
Regardless of political views, how does this item fit on HN?
This is so bizarre, what questions are you getting that require you to refer to the rfc - something with such detail that it covers things like how many bytes are allocated to which field.

If you're doing something so niche like some kind of network analysis tool, then your colleagues should already have the rfcs as a very basic reference.

Otherwise, if someone is asking very practical questions like, how to add a cname or something, then rfcs are way too theoretical.
If you don't have to also buy the car, this might be reasonable
Tangential anecdote: my dad sent me to a typing institute(!) during my summer vacation because he had no hopes of me being able to do anything beyond clerical work and knowing typing would be helpful in that area. Decades later, I am grateful for that experience because being able to touch type is a gift that never stops giving.
Yes but, how much of that company growth came from not paying employees a fair wage? How much lost income tax would be recovered if the minimum wage tracked closer to $27 (forget $15 - lol). Not a specific comment on BG/MS, more generalized to billionaire company ownership in general.
I would refuse the meeting until they have at least attempted to use the resources you provide. If they do and still have issues, you can talk with them about what may be holding them back from using them effectively and make some changes on your end.

It's about firm boundaries. I remember reading a story on r/TalesFromTechSupport where the OP put down his foot about an older lady not googling things before asking him simple tech-related questions. At first she was annoyed, but after learning to Google effectively before coming to him for harder question she learned a valuable skill and later thanked him for setting those boundaries.
Sure, much like the Kelly criterion would tell you. If your life savings are $50,000, and someone offers you an even odds bet but with a 70 % chance of winning, you get optimal growth by wagering $20,000. However, that assumes you'll get a large number of similar offers so that you can make your losses back later if you get unlucky now.

That said, growth is pretty close to optimal even for smaller wagers. This plot shows growth rate as a function of wager size: https://www.wolframalpha.com/input/?i=plot+log%2850+-+x%29*0...
TOME is such a great game. I've played Nethack since early 90's, thereafter Angband and Zangband and finally TOME. TOME is very polished, slick, beautiful, full of depth, different challenges and styles. Also actively maintained. Sunken so many hours while listening to talk radio.
You can look at some aspects of the theory for anthropocentric climate change for falsifiable statements. The explanation for the rise of carbon dioxide in the atmosphere is that humans burn fossil fuels, such as coal, oil, and natural gas. All of which contain no carbon-13 isotopes because of their isolation underground, whereas the carbon released from living things does contain carbon-13, which is formed from the presence on cosmic rays. If nature, and not humans, are the source of carbon emissions, we would expect to see no decrease, with respect to time, in the proportion of carbon dioxide molecules containing carbon-13 atoms in earths atmosphere.
Time is not really a good measurement in this case. It was doing quite well until it was unfortunately nearly killed off by WW2. It's recent rise in popularity has been due to the tools people have been given to create and host various forms of media and learning platforms on the internet.

If you poll, you will find today that most people will not be aware of the concept of an international auxiliary language. This gives the adoption of one (not necessarily Esperanto) some kind of hope.
Only when demand exceeds supply and people have that extra income.

Edit: which is common in desirable places with lots of well paying jobs.

There are cheap places to rent and buy in the fly over states but not as much opportunity, hence the price
This sounds like GPT-3 if GPT-3 were a lot worse than it is -- so more like a run-of-the-mill spambot that slipped by Akismet.

Harsh, I know, sorry, but....look at your comment. It could literally apply to every 'controversial' article ever posted on HN.
> Also, if you have multiple accounts you can easily switch between them by changing the 0 in the URL to 1, 2, 99, ect...

> Like this...

> hxxps://mail.google.com/mail/u/0/#inbox

> hxxps://mail.google.com/mail/u/1/#inbox

Yes, though it is worth noting that the index is dependent on the order you log in to the various accounts.

I no longer use this method, preferring to give each Google account it's own dedicated profile as that seems to play nicer with 3rd-party sites and services that are logged into using a Google account.
The name should be oldOS, not OldOS.
Fight who?
>Soldiers naturally face immense PTSD from harming human beings.
Yes of course. That's why the most important part of military training is to break you down and turn you into a mindless killer who obeys orders. Doesn't always work but that's the goal.
A mystery cube, a secret identity, and a puzzle solved after 15 years
The "pipes" has some better examples - Lucid is a fantastic example.

My own programming language Intonal (https://intonal.io/text) is a practical continuation of Lucids ideas, in the first steps of seeing production use, combined with a "Haskell-lite" type system (control structures, typeclasses, second order functions, custom data types/enums, etc) - Turns out the "pipes" or data flow approach works really well for audio, also turns out there was/is a lot of to figure out about how memory works in such a language.
That's the sound his co-workers make when he strangles them!
If I can watch videos or sleep behind the wheel, 8.5 sounds reasonable to me.
And often the papers they host were paid for with public money.
English and a long time Finnish learner/speaker (because of migration).
Free tool to analyze companies in less than 60 seconds
Haven't read it but since it from the same author who writes these 'to the point' blogs - https://2ality.com/ I believe the quality would be good.
Oh my sweet summer child
Where are these remote jobs paying 500k?
I really like the idea of having permissions for what kind of experience an app can show. For example, if Facebook had a way to disable infinite feeds and disable videos then I'd be more likely to use it on my phone (whereas right now, I never use it).

We have permission settings for things like camera, microphone, and file system access. Why not go an extra step and add permissions on how apps take up our time.
The Red Cross Blood Donation centers perhaps come closest to doing this. From their emails, it sounded like they never saw widespread active antibodies (until a few months ago).
Could you tell us more about your project?
Free market 101: charge passengers based on weight?
Do you literally read it aloud? How do they react to that? Are they embarrassed they didn't read it? Do they notice they could have gotten the information from the documents? Have you ever pushed back on a meeting request?

But that's about how to push them. Have you asked them if the documents are hard to read? What are their length - are they overly long? Have you done any testing to see if they even open and struggle with the documentation before they call you?
> you also lose most of the leverage that comes with specialization and having critical knowledge

Your value does not disappear when there is redundancy within your company. If it is a valuable skill there will always be a demand for it outside, and now you can also claim that you are also capable of coaching others in that skill. If the skill is not valuable to the outside world and is a niche to your company, I’d say you still want to move on from that skill exactly because it is not transferable to other jobs. What if your company goes bankrupt?
The real question is - did the company fire him for that? I'd wager a guess that it did not. So, it worked out for him.
An hour can move you 60 miles on the highway, which is likely at least 2 gallons of gas. So gas would be $6-8. $8.50 seems like a great deal.
Every lesson has to be learned by every subsequent player the hard way, right?

500K, run-rate, MRR — it’s a simple equation.
This concept is really well put together, and I would love to see it come to life.

That said, this quote made me laugh out loud

> For example if you're struggling to use Tinder responsibly, you could create a condition that you can only use the app while FaceTiming with a friend.
I would also add Cataclysm: Dark Days Ahead, a massive survival roguelike set after a zombie apocalypse with a healthy dose of Lovecraft. Actively developed, huge community, and a ton of features, from crafting, farming to implanting bionics on your body and building vehicles from scratch and driving them.

Probably the only game out there that lets you go from escaping a burning building in a bathrobe to running over zombies in your custom Mad Max style electric RV.
How about to use the internet? Or to use the smartphone you already paid for?

Attempts at renting your own hardware back to you should be rejected on sight.