skysight-inc/HackerNews huggingface dataset:
These results are less accurate than Google Translate. But they are far faster to get, and far less expensive to generate: https://cloud.google.com/translate/pricing — our goal is here is speed. We want to search through many possibilities as quickly as possible.

The word vectors have been aligned in multiple languages. Using an approximate nearest neighbor search we are able to find the nearest vector to the input in multiple languages very quickly.

To keep the example simple, we did not try to filter the data through hand-built language dictionaries. In fact, we simply drop words in other languages that also appear in the English .vec file. Words like "ciao" appear frequently enough in otherwise English sentences that the example code drops it from Italian, and so is not shown in the results:

% curl -s "https://dl.fbaipublicfiles.com/fasttext/vectors-aligned/wiki..." | grep -n ciao
50393:ciao 0.0120 ...

One improvement would be to filter out any words that do not appear in a hand-curated dictionary instead of filtering out words that already appear in English. We decided not to show how to do this because we'd already introduced a few concepts, like aligned word vectors, approximate nearest neighbour searches, and wanted to keep the example as simple as possible.
For drugs like MDMA from cooperative chemists

For drugs like cannabis from neighbourhood indoor growers.

For drugs like synthetic opioids (ad Ketamine) directly from the pharmaceutical companies.

For drugs like cocaine and natural opiates they are imported from revolutionary groups mostly. This one is tricky, as the other end of the trade tends to be fairly brutish, so there is a thriving "middle man" business.

I do not get your point.

My point is that dealing illegal drugs is a community service. The laws are complete bullshit, no body with half a ounce of sense thinks they are socially useful, they are maintained for reasons of brute power and political lag. They are failing
There's also nothing in medical doctor training, as well. Or in fact in most specialist training - e.g. my father-in-law who's an ObGyn couldn't you how an mRNA vaccine works beyond what he learns from reading the same material I can - it's not a relevant part of his training beyond "they work and here's the list you should be giving babies as soon as possible".

Medical professions, the ones you interact with as a patient are essentially highly specialized mechanics for the human body.
That's reassuring from a public health perspective, not so reassuring from an individual perspective. When it comes to one's personal risk, you have a sense of control over not getting COVID, and/or are personally at low risk of severe complications, which can weigh in favor of avoiding a vaccine with extremely rare but serious side effects.
> However the topic at hand is the relationship between rust's type system and c's; hence unsafe is completely uninteresting,

Gotcha, I was just trying to clarify the semantics of unsafe, lots of people think it suddenly lets you do whatever you want, and while it will let you, that doesn't mean that you can, which is an important distinction. You're right that this puts it in the same general category of C in a theoretical perspective, I think practice will bear out that it's not a binary proposition, but time will tell :)
Which Chinese vaccine are you talking about? The two common ones are Sinovac and Sinopharm; neither uses a modified adenovirus. Also, neither of them have been taken by billions of people.
If you actually read further than the first paragraph, you would find plenty of examples where the dogma is broken.

>Computational Biologist at Ohio State

Oh, come on! And you didn't knew about it!? Sad.
The tutorials provided by VPS providers like Digital Ocean are a pretty good way to learn how to setup a VPN or any other common webservice yourself. They have a pretty well maintained library:

https://www.digitalocean.com/community/tutorials/how-to-crea...

etc. I'd also second a recommendation of wireguard over OpenVPN - it's far simpler to configure too.
What was the profit motive behind hiring her?

I’m not challenging; I’m genuinely interested and baffled by these moves. I’d like to understand that chain of logic that ends in money.
I'd argue they make it less risky. Ransomeware has been around since the 90s, just not nearly as prevalent as it was harder to do without getting caught. They could easily instead demand somebody mail cash/money order to an abandoned address or mail forwarding service.
Robert W. Malone _claims_ to be the inventor of mRNA vaccines and on his web site there's a long explanation of how he had the patents first and so on (https://www.rwmalonemd.com/mrna-vaccine-inventor) but I can't find ANY reference to him being the inventor of mRNA vaccines other than pages and bios that he has written himself. So I'll take it with a pinch of salt thanks.
An Absence of Trust (Or Maybe Not)
I don't agree about those examples.

- Powered flight: from first demonstration to commercial application was less than a decade.

- Computation: I know about Babbage and Lovelace, but from the invention of the transistor to practical computing was years to decades depending on how you count.

- Electric motors: similar

- Batteries: don't know the history, probably they were known in ancient times, but it's not like their development was held back by anything, people just didn't have much interest in finding applications for them.

- IC engines: At most two decades between invention and useful work. But probably less by more reasonable definitions.

- Rockets: Again, depends on what you count as successful. But people had working versions pretty fast.

Fusion is unique in that we've known how to do it for 80 years, spent billions of dollars on it and outside of scientific research and weapons have no real applications for it. The only way to make the timeline for others seem similar to fusion is to stretch the start date back to when people imagined being able to do something, e.g. to put the start date for powered flight at da Vinci, but you could do this with fusion too (perpetual motion machines?) and make it begin arbitrarily back in the past as well.

In basically all other cases of technological development precise characterization of the underlying phenomena to commercial application takes a few decades at most.

Edit: Also, those older technologies had the massive disadvantage that materials were much harder to get and of less consistent quality. Fusion research has basically not had these problems.
The alternative here is ignoring the software engineer, and instead asking the crazy person on the corner who’s shouting at the sky and wearing his underwear on his head.

Getting the perspective of the software engineer is a reasonable step, and certainly better than basing your beliefs on the rankings of the insane person.
> The messaging on masks should have been that only n95 or better are worth the time

Which is simply rubbish.

Masks of all kinds will prevent transmission albeit with varying levels of efficacy. And most importantly they impact human behaviour in ways which prevent transmission.

Not to mention that N95 masks are more expensive which would have reduced its use by people who are poorer and are far more likely to spread the virus i.e. they are more likely to have multiple jobs, travel further for their job, work longer hours etc.
A good Email client can do a good job of displaying the messages, and sorting them into appropriate folders.

But if you are not subscribed, then all the web ui's I've seen for mailing lists are painful to use.
I'm debating this for myself currently. I'm a teacher and, in the low CoL area I live in, I make pretty well with good insurance and decent retirement because of when I started teaching. I am, however, getting a leave of absence to go to Ireland to pursue a masters program in Applied Math and Theoretical Physics.

It's really tempting to just stay and work a data science job, though I do enjoy the time teaching gives me off, the fact it'll pay off my loans and that I can live comfortably with plenty to save to travel abroad for a few weeks every summer (I realize I might be one of the few teachers like this and I credit it solely to being single and no children).

And, yeah, I'll get state insurance when I retire, but it just sounds nice living in Europe (using the Ireland masters as a jumping-off point for networking) and not having to worry about it at all, even if I have to give up a lot of the stuff I value about teaching (namely, 75+ days off a year and a decent work schedule)
Most safety features are nothing like lane assist. Lane assist is not a representative example of what most safety features in a care look like. Most safety features are crumple hoods and pillars, safety glass, airbags and seatbelts.

Additionally, you think it is a more feasible solution to change culture than to make the safe operation of a car less reliable on the human element? How exactly do you "make people better and more attentive?" Training? Please elaborate on what that would look like.

Cars are designed a lot more thoughtfully than they used to be. An example not related to safety is cupholders. Remember when two flat rings on the dash were considered acceptable for holding a cup? Safety wise I'd say designing contingencies against inattentive drivers is thoughtful design.
> I couldn't care less about control

...

> just getting six people in a war room for a week and getting that hard problem done

Sure, it is not about control, yeah yeah.

Good riddance.
I have no idea what on earth you are trying to say to me.

I'm a former homemaker whose interest in understanding genetic stuff in layman's terms is rooted in having a deadly genetic disorder.

I know lots of useful health info and I had a class in medical terminology as part of a certificate program while doing a corporate job that involved reading medical records all day, but I sometimes have significant trouble following scientific discussions and I am deeply grateful for the many people on HN who have kindly and respectfully explained things to me in layman's terms because it has literally helped to save my life.
AI System Outperforms Humans in Designing Floorplans for Microchips
See, there’s that dodge. No concerning quote. Not even a page number. Just dark, vague assertions.

I know it’s all over the web; I skimmed quite a few pages. You’re claiming concerning stuff lurks within - support the assertion.
Might be referring to this study:

https://trialsitenews.com/wp-content/uploads/2021/06/Pfizer-...
Why can't they just build a train already?
Here you go! https://www.nature.com/articles/s41586-021-03250-7
This is very wrong. You mean nucleotides, not chromosomes – but they don't need to be replicated, so long as the codons are. The custom not-found-in-nature nucleotide is equivalent to a natural one, for all purposes except being detected by the immune system.

The mRNA is at no point transcribed into DNA. I think this is what you meant – but it might help if you researched the mRNA vaccine before posting internet comments!
> worth the time

is completely relative to the observer. a piece of shitty fabric over your face won't stop n95 levels of transmission but it is better than nothing. To some of us, it's "worth the time" to be less likely to spread even if by a very small margin.
U.S. Billionaires Faced Tax Rates as Low as 0%: ProPublica
And if my grandma had wheels she'd be a bike
Exactly. The vaccines did not go through the FDA’s typical approval process, they got emergency approval, but the standard approval process is still ongoing. mRNA vaccines have never been used in a large scale setting outside of clinical trials before. Are they safe? Almost certainly. Do we know that for sure yet? No. Do the benefits outweigh the risks? For me, yes.
The market does. Porsche will sell you a stripped out version of the car for thousands more. Webbing pull tab instead of a door handle.
Obligatory xkcd: https://xkcd.com/2425/

I haven't got one since I've had a positive last year. And I was afraid because it's new technology and too fast in delivery. However as time goes I'm not afraid of it anymore and am planning to get one.

However my country only provide sinovac or AZ. I prefer pfizer biontech or moderna.
Most of the Q-idiots are of the same mindset. "Go do the research" is a common phrase.
> I scanned most of the Pfizer trial and was wondering why we expected the immunity after the vaccine to last longer than natural immunity. A typical infection can last for several weeks, so your immune system is presumably exposed to the virus for a similar period of time. And after a natural infection I hear 6 months being thrown around as a typical window of immunity. But I was hearing claims of vaccines lasting for years, when they were only in the trials for less than 6 months. Why is this?

Because the science on the immunity of coronaviruses is very poorly understood because previously they gave us the sniffles for 2 weeks and didn't cause the worldwide economy to shut down so nobody studied them well enough.

And studies had been done which seemed to showed that immune waned after 6-24 months with common cold coronaviruses.

More recent studies have now found that while people will get reinfected with HCoV-229E that immunity to an individual strain seems to be very durable/permanent and that on a scale of years the virus eventually mutates to achieve escape immunity and reinfects:

https://journals.plos.org/plospathogens/article?id=10.1371/j...

Note that was published as a preprint back in Dec 2020, so They(tm) didn't have this article back last summer when the question of reinfection was first raised.

6 months of immunity after natural infection was what was _guessed_ by some cautious immunologists last summer, based on the prior studies of coronaviruses. With better studies and with more time spent studying the only coronavirus that actually matters it looks pretty confident that its going to be more like years. The vaccines produce stronger results measured by neutralizing antibody titers so we _guess_ that they'll be more certain to hit those kinds of timelines. We still don't understand how long it'll take for this virus to achieve escape immunity, but the safer money is on the idea that it'll become endemic, but second time around those with natural or vaccine immunity won't be anywhere nearly as severely affected (e.g. https://science.sciencemag.org/content/371/6530/741)
> The best I can do is give it to a sales rep in the service department and hope they send it "up to corporate".
Many car manufacturers advertise the prestige of their brands. One of the reasons the Porsche 911 has the highest profit margin of any car is the prestige of the Porsche brand.

Here are some examples of how Porsche advertises its electric cars:

https://www.youtube.com/watch?v=92sXWVxRr0g

https://www.youtube.com/watch?v=8m31EgQkswg

https://www.youtube.com/watch?v=6gozMJnzZhU

https://www.youtube.com/watch?v=Abq-ZjJZ4oo

https://www.youtube.com/watch?v=WvGr0uDKthI

https://www.youtube.com/watch?v=m0793euQNL8

https://www.youtube.com/watch?v=CBRwF0LU3Ys
His views are valid, but it would be ridiculous to claim he's every black person or even most black people.
People will trust you if you demonstrate leadership.
Author here: to be clear, I asked if it was OK to start later after the family vacation, but my manager said I could just start earlier and take the family vacation as a large amount of PTO. There wasn't anything malicious there.
That's a little chauvinist! Birds regularly run circles around mice... er, so to speak.
Yes, Astra-Zeneca has been shown to be repeatedly poor against variants, a big story in the UK right now is whether the increase in cases and sense of being behind the US is due to gov't overly committing to a shoddy vaccine, or if it's variants burning through unvaccinated populations.

The picture isn't nearly as rosey as OP makes it sound, unfortunately: sort of a gish gallop about knowing the rate at which we can expect buffer overflows in C, but in reply to a comment noting we don't have an ETA for ending security vulnerabilities, so they unintentionally implied the picture is good.
These are mostly the negative externalities of using computer code.

It is no harder to collaborate with Perl than with R (been there done that) or Julia (have not done that.

PDL is addressing your point about libraries.

Horses for courses. If your research involves streams of text (a lot of things are streams of text) and transforming them then Perl is a likely contender as the best choice.
The thing is, any random person can be a genuine skeptic by simply having a lack of expertise in the subject. It’s much more interesting to hear from s skeptic that is more than a layman, otherwise we’d just be inundated with skeptics.
Worth pointing out (maybe?) that dogs-the-domesticated-animal are less closely related to the African wild dogs than they are to wolves and coyotes.

All of which are pack hunters and smart ones to boot. It's just that your first paragraph gives the impression to me that "wild dogs" are the same creatures as domesticated ones, just wild, when that is more true of the wolf than it is of the African wild dog. For instance, the African wild dog and the domestic dog can't interbreed.
Engineering a consent sandbox to eliminate annoying pop-ups and dark patterns
Business majors/MBA types are infiltrating IT. Your admin work is through the roof, culture is eroding, a s these jobs just aren't fun anymore.
Because a passport represents a centralized storage of medical data, and that's always a bad idea.
Why do you think that? Perhaps they might have access to some paywalled medical journals, but other than that I don't see why they would have a better idea of where to look than an interested and scientifically literate person who hasn't been to medical school or practiced medicine.
> And there's evidence of it happening in plenty of other contexts,

No, there isn't; “mRNA chromosomes” aren't a thing. The comment you replied to made as much sense as “the server rack isn't duplicated on the hard drive”; there's no evidence of it happening, because no possible real-world event corresponds to those words.
Didn't Linus apologize sometime ago for talking like he talked on this list. Personally, I agree with what he says, but I dont like the tone.
Even the term antivaxxer in this case is divisive and kind of presupposes that everyone should be a provaccer. Since we are not going for herd immunity, everyone should assees their own chances before making an informed decision, which in the vast majority of cases will be to vaccinate themselves. But there are specific sideeffects in specific groups that have been documented
I personally know two people under 60 without any co-morbidities die from Covid19.

The bug is statistically less dangerous to that group, but it is still pretty dangerous.
That person may or may not be s lost cause but in that particular forum, Linus has all the authority he needs. He might have made an antivaxxer an even stauncher antivaxxer but the message is received by hundreds of others. I absolutely agree that this tone isn’t how you persuade someone. It’s not how you’d talk in private. But that’s not what happens here. This is hopefully a net positive despite not persuading the poster he replied to.
A couple of comments:

The big problem with "natural" infection and response is that you have no idea what your body locked onto and made you immune to.

For example, my mother-in-law had measles 4 times. Her immune system clearly doesn't lock to the same piece as everybody else's.

For Covid, most of the time the lock point is the spike protein, but sometimes it's not. And sometimes it's different pieces of the spike protein. Some of which mutate quite quickly.

So, your immune system is spending a lot of energy "training" to lots of different pieces of the virus. That's what it's supposed to do.

But it's specificity isn't anywhere near as good as the vaccine which is engineered to give you a response to exactly what seems to be the most relevant chunk of the spike protein.

Of course, if the virus mutates that spike protein area, the specificity is useless. However, if that section of the spike protein mutates, the virus also gets a lot less problematic as it seems like it won't be able to bind to the ACE receptors.
Were you saying something racist? I'm just asking.
Great story, it’s stories like these that make me still hold onto my undergrad work (as bad as it is). Maybe one c#, Visual Basic, asp, php, t-sql and other esoteric projects will be looked at as relics of the past.
Bitcoin Has Fueled Ransomware Attacks
> So we have analogs and precedents we can use.

You gotta be careful. Biology is not always "linearly interpolable" like that.

> "if someone majority were to go wrong it would go wrong in the first few months, and not 5+ years later".

You REALLY can't say that. There are plenty of medical conditions that will not manifest at all until years later.
You can, but almost always people weigh this up incorrectly.
> They are actively trying to spread even more misinformation. This should be contained just like we contain viruses.

This is the original definition of "meme" rooted in evolutionary biology. Disinfecting with liberal doses of reason, frequently, and vehemently is certainly warranted.
This is a very HN comment, because it ignores that a lot of people are paid for being physically present somewhere (not for their output).

I love the idea of a 20 hour workweek, but I also understand that the harsh reality is that it would make things like construction, building security, janitorial services, etc. 2x more expensive.

I personally think that would be a boon for society, but given how much everyone is worried about (largely transitory) inflation today, IDK how willing they would be to accept that inflationary pressure.
Thank you for sharing the link. I do note that this is an observational study of 255 people. It contradicts a randomized trial with 1,561 people in the HCQ-arm alone vs 3,155 receiving usual care (RECOVERY).
RNA can conceivably alter human DNA? How, you might ask, given that human cells don’t use reverse transcriptase? Because due to ancient viral infections there’s a LINE-1[1] gene that codes for it. So it can’t be ruled out that RNA ends up encoded as DNA.

[1] https://pubmed.ncbi.nlm.nih.gov/25478632/
Serious question, how is a vaccine passport any different from a proof of immunization (one common form being the International Certificate of Vaccination or Prophylaxis), which is standard fare for travelling to/from many countries already? We’ve been using these to combat the spread of diseases like yellow fever for years.
Is there somewhere where we can suggest/vote for the next integrations? I can only seem to find a message that you are adding more integrations. We'd love to see Microsoft/Office 365 integration, and GitLab.

The tool looks awesome, exactly the right kind of metrics, without the invasive accounting for every second that others have tried to enforce in the past! Excellent work!
It has become super easy to hire from FAANGs all of a sudden (actually, not from Facebook, because they're staying remote)
All due sympathy to your family member, but there is potential for serious side-effects in almost every medical intervention. It's true that these vaccines received emergency authorization, so the known unknowns are greater in number than usual, but this vaccine appears to be safer than many commonly prescribed medications. It's as irrational to be anti-vax as it is to be anti-medications. First do no harm does not imply a guarantee against all potential harm in all cases for all people (the world is too complicated to guarantee such a thing).

(I do think Western medicine is slavishly focused on medications and relatively blind to prevention but that's a separate issue)