skysight-inc/HackerNews huggingface dataset:
None of this vision would work for a variety of reasons, but the biggest one is that insurance companies are not going to agree to pay for medications that are not proven effective.

Your personal freedom to try whichever medications you want would be limited unless you are willing to pay out of pocket for everything.
I'm so sorry for your struggles and those of your family - Alzheimer's is a terrible disease and I too want to see it treatable as soon as possible, but in this case, if the data is inconclusive, then the drug is not actually a treatment for the disease, that's the point. The purpose of all the trials and tests is to ensure that a) the drug actually does what the scientists in the cutting-edge labs think it does, and b) that it's safe or at least has manageable side-effects.

I have a relative with this disease so I understand the drive to find a cure but it helps no-one to push through a drug that may end up causing more damage.
Honestly, I thought this was common knowledge. I don't see it as a form of corruption, it was encoded into law primarily because most environmental regulations were passed in the midst of the Cold War. As a country, at that time, we didn't want to do anything which might impede the progress of military advancement and force superiority, which meant that national security concerns utterly trumped newly formulated (and somewhat hotly contested) environmental regulations. I don't think there were any backroom deals involved, I believe all parties, including the staunchest supporters of these regulations at the time, were in support of military exemption.
Taking advantage, in any way shape or form, of someone else's efforts, against their will, which efforts and work product were not in public but expressly in private, isn't sticking it to the man or fighting the power structure.

It is just taking advantage of someone without their permission. That's all it is. There's nothing revolutionary or awesome about it. It isn't novel. It isn't creative. It isn't rebellious.

It is simply an unethical use of force.
refer to Capital in the Twenty-First Century

yikes, no thanks, keep it academic.
If you are against desperate people buying drugs to solve their problems and as such the government should work to keep drugs away from people... tell me, are you an avid supporter of the War on Drugs as well? I hope I don't see any comments by markus92 on future threads advocating for drug legalization, or an easing of restrictions on recreational drugs, or an easing of punishments for drug abuse. Because to say that I don't have the right to try a drug after careful consideration with medical professionals -- DOCTORS -- to potentially help alleviate my dying mother's illness... while any junkie on the street is entitled to getting high on whatever pharmaceutical they can get their hands on. Is morally repugnant.
I guess most of these men are not living in houses made for multigeneration living, i.e. with wings, separate entrence or separate houses or similar.
As long as ransomware is possible, it will continue. Criminals will come with a way to be paid, and some of those ways would involve some level of physical violence and organized armed intermediates.
> You mean to facilitate money transfer between banks it only take a bit of electricity....

So nice to see that bitcoin is giving out loans. Is available to my grandmother. Can be used to pay at every corner in the city. Or does it?

> Gtfo, what is this republican rally??

I am always amused by the limited world view. Its not about democrats or republicans, in this world (you know, that thing outside the us?). There are more political views than their agendas.

> How about we stop fossil fuel lobbies attacking green initiatives, ...

It's nice that you know so many other things that should be addressed as well. But it's no reason not to stop bitcoin from wasting all that power.
I guarantee you that you won't "get by" at a FANG doing bare minimum for more than a month.

Also, I doubt anyone doing this kind of work will get get a second FANG work after failing the first.
As someone else commented above - there is precendent to this, this is exactly how the HIV epidemic was approached. I was as upset about this decision as everyone else on this thread, then I read this[0] and now maybe not so much.

[0] https://forum.quartertothree.com/t/wtf-is-going-on-at-the-fd...
Wow, it has quite some history behind it [1].

[1] https://en.wikipedia.org/wiki/Raku_(programming_language)
I think you're making a mistake in assuming the Linux kernel maillist is a free speech, anything goes, zone it isn't.
The next change Google will try is replacing the URL with just "The current one".
The Myth of Artificial Intelligence
Random, sparse ransomware attacks are absolutely benign compared to what a wartime enemy would do. If you don't think so, you haven't properly imagined the serious, extensive, real world damage that could be done by coordinated simultaneous attacks. Look at Stuxnet's destruction of machinery and then imagine that applied to a wide swath of the economy, including basic infrastructure like water and power, all at once.
I've written a lot of software against GPUs, albiet some years back. The main challenge was that many of the best libraries had CUDA support (or CuDNN support on top) but not support for other GPU lines' frameworks.

Getting CUDA to work well is hard. Not hard on your laptop, not hard on a particular machine but hard to work everywhere when you dont know the target environment beforehand -- there are different OSs, different OS versions, different versions of CUDA, different cards with different capabilities. But we did get it to work fairly widely across client machines.

The same effort needs to be put into getting things to work for other manufacturers, except a layer deeper since now you're not even standardized on CUDA. Many companies just dont make the investment. Our startup didn't, because we wouldn't find people who could make it work cost effectively.

What I really wish is that the other manufacturers would themselves test popular frameworks against a matrix of cards under different operating systems and versions. We see some of that, for example, with the effort of getting TensorFlow to run on Apple's m1 and metal. I just dont see a random startup (e.g., mine w/ 12 employees) being able to achieve this.

For example, if I know from the manufacturer that I could get TensorFlow X to work on GPU Y on {Centos N, Ubuntu 18/20}, I would gladly expand support to those GPUs. But sometimes you dont know if it is even possible and you spin your wheels for days or weeks -- and if the marketshare for the card is limited, the business justification for the effort is hard to make. The manufacturers can address this issue.
Is it contentious? I thought it was pretty accepted. Pretty obvious too, even just looking at the people I know.
Yeah, imagine the name of your product sounding like the Western Australia Party!
https://usesthis.com/interviews/rob.pike/
Because those who want "just heart rate and temperature" will want more in future. We aren't setting that precedent and opening up the possibility for more.
Is it in Cyrillic or Latin ? Do you know if its available online ?
Does anyone know how LEDs built into RAM modules are controlled from a hardware point of view? Can you just send control information over the channels that data to be stored in memory also uses to get into the module? Does it mean that you need to install drivers for them? What happens if you do not?

Update: DDR4 modules seem to have pins for a built-in SMB/I2C bus. Maybe this is used for controlling the LEDs. // It looks like it:

https://www.reddit.com/r/hardware/comments/aiwrt2/how_does_r...

https://gitlab.com/CalcProgrammer1/KeyboardVisualizer/-/issu...
Setting aside that you ignored the "and China", I believe Crimea would like a word.

Edit: it is worth noting that the joint chiefs chairman just testified to congress that Russia and China are the greatest physical threats to the US.
I've seen it...I just don't personally know anyone that subscribes to it.

Just like I don't know anyone that plans to retire off lotto winnings? Most of the people I know, might dream a bit about 'hitting it big' - but none are expecting cash/fiat to go away.
How did you settle on Mg cloride?

Mg orotate doesn't upset my tummy. Determined thru trial & error. I tried reading about the differences, but failed to understand.
Yeah, I would agree with that: it's payday loans with a friendly face. I once worked with someone who had previously been an exec at Klarna, and he had some 'interesting' stories about how they did credit decisioning. One of the examples that always stuck in my mind[0] was declining people with five or more vowels in their last name, because it was an effective proxy for West African people. (I remember that one because it also picks up my somewhat posh double-barrelled English surname, so I suppose I would have been collateral damage.)

[0] I should say I can't remember for sure if this was from his time at Klarna or somewhere else, but it was at least illustrative of the kind of people and the culture there.
Another reason your new term is superior:

"Flexible-location" implies that I might not live within commuting distance of one of my employer's offices.

"Work-from-home", so far, has been abused by employers who are hellbent a so-called "hybrid" model and still want to require that employees live within commuting distance. "Work-from-home", in any proportion less than 100%, is worthless for someone who doesn't want to live in the 'burbs.
It's actually more trust, because any bad consequence is reduced. It feels like less because it's easier to trust, but the real world impact is of the real thing, that is more.

That's why an effective police, punishment for business crimes, and law enforcement even when the person moves into a different place are important. A more trusting society is a happier and richer one, so we should make it easy to trust.
He cites: "citing fraud, criminal use, and financial instability" - not environmentalism.

Also, that argument only applies to PoW coins, not PoS coins.
But that half dose has to be stored in conditions much cooler than the AstraZeneca vaccine. Obviously there's a place for both but the portability of the AstraZeneca and J&J vaccines can't be understated.
And CDN's offer flood / ddos protection as well.
I agree with this. Everybody I've met who complains about sleep has terrible sleep habits. When I get loose about my habits, my sleep deteriorates, but when I'm good, I sleep like a machine: asleep within 5 minutes, out like a rock, spring out of bed in the morning like a fully charged battery. No morning grogginess; it's like a switch. No drowsiness during the day. I haven't had caffeine in years and never feel the need because I get proper sleep.
Not the OP, but I don't really get it. Maybe I'm missing something.

They're basically creating cash accounts? Not quite a bank but... not far off it. I feel like a simpler solution is just mandating that banks are required to offer a basic cash account at a set maximum cost.

It doesn't feel like the bitcoin part of the experiment is really doing anything special. It's all in a single app and all held by a holding org. They just track who has how much of the reserve.

Not really the free and open bitcoin?
That's not catastrophic thinking then. Catastrophic thinking tends to fixate on irrational concerns, like, "Did I run over a person on my drive home and not notice" or "is that stranger planning to kill me?".

"prepare for the worst" is super vague, because the worst is unbounded in implausibility.
Well, the Pfizer shot works doesn’t it? It’s extremely similar to Moderna and its standard dose is 30% of the Moderna dose.
Senior .NET Web Developer at Caspian
Clearly not all of the military should count towards the dollar’s climate impact, not even close, but some of it wouldn’t be needed without the dollar, and that should count.

What portions of the government and military could be dropped if the US dollar hegemony didn’t need to be maintained? What could be dropped if we didn’t need banks to handle money?

This is of course impossible to quantify accurately, but it shows the picture isn’t as simple as “ban BTC because it uses more power than Argentina”; an angle that’s thrown around a lot around here.
You are correct that per capita doesn't matter to the global climate but it's only relevant because regulations are enforced on a nation-based fashion.

As a Chinese national living in the U.S., I would like my fellow countryperson to have the same standard of living as an average American does. Unfortunately this view is not shared by many Americans, including Obama [0].

[0] "...if over a billion Chinese citizens have the same living patterns as Australians and Americans do right now then all of us are in for a very miserable time, the planet just can't sustain it": https://www.abc.net.au/7.30/face-to-face-with-obama/2673356
Yes, because while it isn't fullproof due to copy-paste compatibility with C89, at least it offers better tooling for safer coding, provided one doesn't code "C with C++ compiler".

Namely:

- proper string and vector types (most compilers allow to enable bounds checking anyway)

- stronger rules for type conversions

- reference types for parameters

- better tooling for immutable data structures

- memory allocation primitives instead of getting sizeof wrong to malloc()

- collection library instead of reinventing the wheel in each project

- RAII

- smart pointers

- templates instead of error prone macros

- namespacing (usefull in large scale projects with prefix tricks)
Our objective is to support the most humans with the least environmental impact, so yeah it does matter - unless you believe certain lives worldwide have more of a right to exist than others?
The argument used in the article is "citing fraud, criminal use, and financial instability"
One day, only the machines will understand.
The one you recommend above seems to have at least some of it in oxide format:

"Elemental Magnesium (Oxide, bisglycinate, glycerophosphate, malate, aspartate)"

Unclear what ratio of each of the above.
I should probably mention, no one I know is taking out second mortgages, risking their homes, or anything else like that.
What the and? $ Is an Individual Contributor?
Exactly, and that's why we use squashed commits.
I don't like it either. It's a struggle to get components that don't include that nonsense. Lenovo workstations are a good alternative maybe.
Nothing that I do is urgent enough to warrant a yell across a room.
Sorry to hear that, it's anecdotal evidence, seems very cliché too..... I guess the question is how would one set up a system of checks and balances...in the case of your friends, sometimes pot is a good phase to go through, it certainly helps the informal economy....and driving ...well seems like they're bored..maybe need more likeminded "friends" to do something creative?
Yeah, there's a few things suggesting that the Moderna dose should be about half what it actually is, but it was rushed to approval due to the Covid-19 emergency and I don't think the dosing got tweaked as much as it could've been.
Right, https://www.cvedetails.com/product/47/Linux-Linux-Kernel.htm...
A simple artifical life / cellular automaton framework would be a great demo for portable compute shaders. I'm looking at this as a potential starting point in my compute-shader-101 project. If someone is interested in coding something up, please get in touch.
Yes, that's a thing now. My 12y nephew just asked for an RGB fan for his birthday... Apparently they're cool
But should we focus our efforts banning things that won’t change the way people have to live? That seems like an easy way to fail.

Further, Bitcoin is not the main issue. BTC being clean or dirty is based on the underlying issue of dirty power generation. How about we ban dirty power generation instead? Attack the actual, underlying problem.
Some interesting constants and series but a lot of Trigonometry, Differentiation and Calculus formulas...More Math than Computer Science I would say.
Astra-Zeneca is not an mRNA vaccine.

The mRNA vaccines (Pfizer and Moderna) have both shown excellent (though in some cases reduced) efficacy against all strains [1], and the protein regions they target have not shown substantial alteration against antibody binding affinity (fun fact: this is "easy" to test - you give people the vaccine, isolate the antibodies in their blood, then test them against COVID in a petridish - so monitoring and change discovery is quick because you're not dependent on finding infected patients). The linked paper is notable, because while efficacy is effected, in tests the antibodies still ultimately inactivate the entire viral sample: no survivors means no natural selection criteria.

Given the widespread of COVID-19, the emergence of strains which do not successfully alter targetable regions for vaccines means that those regions are not easy (read: lead to reduction in fitness) to change. Similarly, the spike protein displays suboptimal binding to ACE receptors (tested by producing modified ACE receptors which have better binding) but there's been little field emergence towards a superior binding motif in any of the faster spreading strains [2], which implies again an evolutionary blockade or dead-end to improvements in that dimension.

Finally, antibody studies have found that in people who have had COVID, long term antibody production sets up in the bone marrow - this was recent research, but thats important because the basis of long term immunity is the development of immunological complexes which keep some antibody circulating. This is a hallmark of most long-lived immunities, and is for example one of the desired (though difficult to induce) end states of a potential mRNA HIV vaccine. [1]

Taken together (and again: you can also just go read what epidemiologists and microbiologists are publishing, plenty is out there) - the consensus opinion at the moment is that COVID-19 immunity is long-lived based on established science from decades of previous experience with vaccinating against viral diseases.

[1] https://asm.org/Articles/2021/February/SARS-CoV-2-Variants-v...

[2] https://www.nature.com/articles/s41598-020-70812-6

[3] https://www.nih.gov/news-events/nih-research-matters/lasting...
Frito-Lay Will Spend $200M on Texas Plant Expansion
If you can get people to believe it, maybe.
While this person is probably beyond help, it effectively stopped him (and others) from writing more nonsense on LKML.

I think this was the best result we could achieve.
This has historically been a challenge regarding understanding the mechanisms of Alzheimer's in the first place, let alone treating the disease.

We know the plaques and the memory dysfunction are correlated. But we don't know whether the plaques are build up of waste product from the mechanism that is destroying memory function or the cause of the memory function loss. If it's merely a waste product, clearing it out of the brain may not only have no effect on the memory loss, it could even accelerate it (if the chemistry of the process is such that build up of plaques interferes with whatever process damages memory). Destroying the plaques may be like picking a scab off a wound.

Biomedicine is hard; none of the systems operate in isolation and everything is intertwined.
Sure it was, Borland and Microsoft compilers already had smart pointers for COM libraries.

Besides even on MS-DOS with frameworks like Turbo Vision, RAII was a common pattern.
There is an old artificial life simulator (darwinbots http://wiki.darwinbots.com/w/Main_Page ) that is inspired by grobots-like programming games. Each organism is driven by its own code that can mutate randomly at each reproduction.

I've been trying to produce a web version of it. This is where I got so far (before more or less desisting):

http://darwinjs.herokuapp.com/
> Is the privacy of many more important than the life of few?

That's a judgement call to which people will have different reactions.

One way to look at it is to ask if there are other mechanisms to accomplish the same/similar goal, then ask which of these mechanisms is most aligned with our values.

A recent Lex Fridman interview of Po-Shen Loh [0] covered a privacy protecting NPI approach. An interesting aspect of the approach is that it works with people's self-interest of taking steps to stay healthy instead of attempting to work against people's self-interest in not being quarantined.

0. https://www.youtube.com/watch?v=6z1JwZbX4dQ

1. https://www.novid.org/

2. https://www.poshenloh.com/
We'll see how that works for them
OpenCL is sadly stagnant. Vulkan is a good choice but not itself portable. There are frameworks such as wgpu that run compute shaders (among other things) portably across a range of GPU hardware.
> This was deemed in violation of antitrust laws for some reason

My best guess at what that "some reason" may be is that it breaks shoddily built integrations like [Teller](https://teller.io/), which, instead of using schemes like Open Banking where available, simply rely on credential sharing.
> [all the banks in the world have] a total [consumption] of close to a 100 terawatt hours a year.

> The highest estimates for Bitcoins annual terawatt hours consumption is 28.67. This means, more than 3 times more efficient than a very conservative calculation of the cost of the global banking system.

I think that a "transaction count" and/or "services provided" are missing from the calculation.

ultimately it does nothing to answer the only relevant question: if the entire banking/financial system switched to bitcoins/crypto would consumption increase or decrease?

I personally think it would be very hard to argue the case of a decrease
> In error checks that detect “impossible” conditions, just abort. There is usually no point in printing any message. These checks indicate the existence of bugs. Whoever wants to fix the bugs will have to read the source code and run a debugger. So explain the problem with comments in the source.

But then the person RUNNING the program will only see this:

Abort trap: 6

And that's all the info you'll get from their bug report.

So please ignore this directive and print a descriptive message always, complete with file and line, and the values that led to the impossible situation. Then you can get helpful bug reports like:

BUG: flush.c:51: buff_offset (65535) must not be greater than 20!
Abort trap: 6
Is there a certain recommended time of day to take these supplements? Like at night so your blood levels of Mg rise to help you calm down?
Agree with you, I have no issues with short commutes. However one place I worked at pre-pandemic had a lot of hot desks but unfortunately not enough to sustain the amount of people who worked there (800 employees only 600 desks). This plus a clear desk policy made the place sterile and I regularly had to find some corner somewhere to try and work, usually on a little chair with no desk.

I had a full office and decent chair at home, but despite this, it was always frowned on when someome wfh.
Three days per week, as opposed to one or maybe two, is still in the you probably don't want a god-awful commute range. I did something like that for 18 months (when I wasn't traveling) with about a 90 minute commute and it really didn't feel long-term sustainable to me.

I can do a two-hour commute (especially if it can mostly be by rail) once a week or so. But much more than that and it gets pretty painful. Mind you, some flexibility is better than no flexibility but it's not remote work by any means.
We aren't even at the half way point of the year and this is already the end of the years session? In a large state like NY? How does anything get done? This isn't some small town in the middle of nowhere.
GGP comment literally just explained what "regulations" are: "corporatism", as you put it. And you want more of them? So you want more corporatism, to solve corporatism?
They did the same with the IRA in Northern Ireland. That’s what happens in geopolitics. Relationships change.

What does it have to do with what is happening in Xinjiang?