> The ideology behind throwing around this kind of allegations is: all facts are fabricated by somebody, nobody can be trusted (they all have a conflict of interest), so we can as well make up our own "alternative facts" that fit our ideology best. In the end, it's just "us against them", so arguments and facts don't matter any more.

That isn't true at all. Mere disclosure (e.g. "Full disclosure: I ran gain of function research for years at NIH, a couple years ago got a ban on gain-of-function research lifted at the White House and our team is currently looking into whether WIV received our funding") is sufficient to mitigate most conflicts of interests. Conflicts of interest exist all the time, but they're fairly easy to disclose (as long as someone has an ethical backbone), and in extreme cases can be mitigated with things like divestment or blind trusts (in the case of financial conflicts of interest).

Suppose your doctor was also a paid consultant for a pharmaceutical company, advising them on their new drug X. One day, your doctor starts telling you all of the benefits of drug X for certain medical issues you have, and she's very enthusiastic about it. If she simply disclosed, "full disclosure: I'm consulting with the manufacturer on the effects of this drug; that said, I really believe in it," wouldn't that entirely change the ethical dynamic vis-a-vis nondisclosure? If she disclosed, you could get a (non-conflicted) second opinion, or maybe you implicitly trust your doctor and go along with her recommendation as is. But if she didn't disclose and you later learned some other way that she has this conflict, you would lose trust.

This is what happened with Fauci and the gain-of-function crowd. They stood on the pedestal of unbiased scientific expertise, failing to disclose their conflicts, and then enabled the browbeating of anyone with alternative hypotheses (literally anyone: scientists had their professional reputations and research funding threatened; social media users had their accounts suspended or posts deleted). Without alternative hypotheses, science entirely falters. Full disclosure on the part of Fauci and especially Daszak would have gone lightyears in evaluating their credibility.

I should note that conflicts of interest do not change facts or true scientific conclusions themselves; that would be ad hominem. But conclusions are typically dependent on myriad facts, and experts have a much better idea about the universe of discourse around these facts than laypeople. A conflicted expert may thus present cherry-picked facts that support his conclusions, ignoring those that cut against them. To be fair, non-conflicted scientists may do this as well, but their credibility is only harmed insofar as they should have addressed countervailing evidence when presenting conclusions. Having a non-disclosed conflict of interest undermines a scientist's credibility and a commitment to ethical inquiry.

In my opinion, the scientific community has severely undermined their ethical and persuasive capital over the past year and even longer. If disclosure were a normal part of scientific discourse where it impacted policy, we likely would have more people who believe that vaccines work, that climate change is a threat (though likely not an apocalyptic one) and that the scientific process generally works. Instead, we have this browbeating culture where not trusting the "experts" is like some sort of scarlet letter, at least until we learn the experts were looking out for their own interests and suddenly they lose their luster. I love science, so I wish the scientific community would get its fucking act together so that large segments of the population on my "side" start to believe in the scientific method again.

Finally, lost in all of this is the fact that gain-of-function was supposed to produce vaccines more rapidly. As far as I can tell, this never happened. The vaccines we received had been researched for a decade through a different program not funded by NIH, and did not depend on gain-of-function research, but instead used unmolested SARS viruses.