skysight-inc/HackerNews huggingface dataset:
TIL I should read the all in one tab packaging and probably buy salt.
One reason Lewis Mumford suggested that if you include the care and feeding of cars and earning taxes to pay for roads and regulations, it could be quicker to walk or use a wheelbarrow.
This isn't really anything new, but nicely summarizes the best case (as far as I've read about it) explanation of the lab-leak theory of COVID origin.

Basically, it hinges on:

1. SARS-CoV-19 doesn't have a direct predecessor virus

2. it has a "weird" furin cleavage site on its spike protein, where "weird" means:

2a. it encodes the amino acid arginine by an CGG RNA codon, which is "rare" for SARS-CoV-19's closest relative

2b. the inserted furin cleavage site coding sequence is misaligned, breaking the codon TCA into two parts, which is (citation:) "very odd, clearly pointing to an artificial origin"

Also interesting that the article refers to "T", which is a DNA nucleotide, as opposed to "U", which is the corresponding RNA nucleotide (SARS-CoV-2 is a RNA virus).
It's a bad idea (regardless of whether it's how COVID originated or not), but there are theoretical benefits. Make a GoF virus, observe how it interacts with humanized nice, see how different therapeutic agents work.

The issue is that it's unlikely that any knowledge gained from the GoF research meaningfully accelerates the delivery of treatments or a vaccine, which is the hypothetical benefit that makes up for the increased risk of escape.
Impressive. Next time my Breville strips its gears, I'll try to remember to give these guys a try. It probably won't be long.
It's a basic research tool used in viral vaccinology. The US had a ban on GoF research that was rescinded in 2018 in part so GoF work could be conducted on MERS.
Congrats! I found that as my child aged, the hardest point was when the cycle time allowed for three hours of sleep for the parents[1]. When it was only two hours, it seemed bad, but was way more restful than three hours. Once it got to four hours, it was much better. If possible, lean on external help during the three hour sleep cycle (grand parents, etc).

[1] we needed both parents for feeding logistics, although often it's not required.
Ah yes, the shipwreck analogy. A very helpful one IME.
I did not know who did that. Thanks! I knew it was misattributed, but was really just a "cliff's notes" of a speech ARIS-stot-ly made.

I have never really cared who said it. It's a great quote.
> I read your list. It’s very comprehensive.

Incorrect. It is a small subset.

> I’d wager an average person from any previous century would trade places with you in a heartbeat. Indeed, I bet an average resident of many third-world countries would do the same.

Sure. Many would. Others would be overwhelmed by the complexity of not just required hours in the day (which tend to increase for the very poor) but also by the many thousands of laws and regulations that can ding us if we run afoul of them. Past that are myriad of requirements from different corps in our lives.

As with some others here, you seem to be confusing (or maybe conflating) 'hard' (as in starvation, disease and invasion) with complex (as in complex).

> In fact, I bet the average resident of the average trailer park ten miles from where you live would trade places with you.

I'll take that bet. Over the last decade we were frequently without food and my wife's mental illness brought ceaseless, life-changing misery to our household. I could go on for many paragraphs but I think this sets the stage.

Where do I collect?
Two: Study how to counteract them if they jump species.

Biological weapons -although an option is a pretty poor option because one, it’s not very lethal, but it can be economically effective.
sounds like a recipe for coronavirus, i hope no public restrooms are like this!
Well there is the "Thanos" theory. Wipe out half the race and more resources and less drain on the ecosystem that is the earth.
No, I just would have to think really hard to recall a front end specialist who didn’t get bogged down in fad chasing or wrote code better than a backend dev half-assing it.
This argument has been brewing for at least a decade from scientists creating new variants of avian flu.

https://www.scientificamerican.com/article/fears-grow-over-l...
Furthermore, did our own government fund such research in China via third party research labs? This seems to be going even beyond the initial “conspiracies” for the virus.
Weirdest anecdote for me: My wife and I were peeling shrimp for dinner and we were chatting how great it would be if there was some kind of tool that would make the task easier.

A while later after we ate, I was browsing Facebook and I was being shown ads for shrimp peeling tools. We had not done any kind of online search, etc. for it. We don't even have any "voice assistants" like Alexa, Google Voice, etc. (Though we both have iPhones so we have Siri).

So how did FB know we had been talking about shrimp peelers?
This. I have recently went through this rather annoying exercise. Received offer was noticeably lower than what I expected for average for the region. I responded saying that what the job entails is worth more based on publicly available information and that does not account for my experience/certs/actual knowledge of how this shit works. They relented, but I learned through the grapevine later that they were unhappy about it, because they had internal data showing otherwise.
FYI, a couple of things to keep in mind:

1. This is a letter to the editor, and is not peer-reviewed[1]

2. This author does not have what some would consider a sterling history of submitted papers[2]

[1] - Difference between Letters and Letters to the Editor: https://pubs.acs.org/page/amclct/about.html

[2] - https://en.wikipedia.org/w/index.php?title=Ariel_Fernandez&o...
Combination washer-dryers are not common anywhere because they are terrible. I live in Europe and bought a washer/dryer recently so researched the options. The main problems are (1) the dryer is half the capacity of the washer (2) double the complexity so lots of stuff can break down.

However your primary point might be correct - European windows are much better - how they can open sideways and from the top - I've never seen that in the states.
As Abraham Lincoln would have said: The best way to predict the future is to create it ¯\_(ツ)_/¯
This is my periodic comment reminding everyone who has to support more than one computer to not buy the consumer versions from Dell, HP, whatever. They're built from whatever was in the parts bin today. No two of them will be the same.
I think there's an element of pridefulness too, in having the ability to manage dense and intricate stuff at all. They're very smart, and it makes them feel good to be able exercise that and juggle and retain so much context at once. And they don't realize how fragile that juggling is, that it's going to take a ton of effort for them or other people to come back to it.

I think this is more prevalent for some languages/stacks than others, too; there's definitely a cultural aspect fostered the language owners or whoever the leaders are.
If that fuse blows, does swapping it help? Wouldn't the blown fuse typically mean the fan bearings are broken and a new fuse would just blow soon again?
> In other words, all three of us made money.

Yes, the three of you made money, but you're forgetting about the fourth investor. The fourth investor won't make money until a fifth investor comes and buys the coin. And so on, and so on. The revenue received by each investor always comes from a subsequent investor. So the OP was right. This is not true of stocks, as stocks do generate income.
Can you elaborate on that? Why journalism in particular? Have you done this? Are you better at docs?
I've seen local restaurants and takeaways with (presumably) similar contracts with the food-ordering aggregators (Just Eat etc).

Some have a clear statement on the website like "10% discount for ordering by phone", others will apply a similar discount when ordering in person, or will put a 10% off coupon (must order by phone / their own website) in with every delivery.
> At least today you can just save up,

Fortunate people can.
I have different take on this

I "know" guy who's conference speaker, so he knows other conference speakers, drinks vodka with them and so on.

He says there's significant amount of bullshit aka things that work nice on slides, things that only work cool in theory, but in practice they arent as great

I think that's what OP meant
Congrats! I write calculators myself from time to time, but this sounds very impressive :) How was your experience using webassembly? Any good guides that helped you with that part?
To me, in this letter to editor, the same story was talked again as in the flagged PDF, in a more succinct writing style. I do not see why one is published and not flagged while the other one remains flagged.
Not the countries I expected in Europe. I have traveled a lot in Spain/France/Italy and seen very few in hotels or private homes/AirBnBs. Let’s change the question: In which countries would it be seen as odd to not have one, rather than them being “not uncommon” as I’d assume this map is? Is that only in Asia these days?
Prime DDG nonsense this, they're pretty much Bing all
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The technological bullshit often makes the device much better.

Let's take an object I'm quite familiar with: an espresso machine. Some like the classic Rancilio Silvia are 100% electromechanical. It's nice and simple, but there are downsides:

* Temperature regulation is very coarse, because it's done with thermal relays.

* There's no timing. All manual.

* There's no water sensor.

* There are potential failure modes.

It's a machine that'll be happy to try to keep pumping nothing until the pump burns out, and that produces variable results depending on the user's timing and precision. Popular add-ons include a PID controller to fix the temperature regulation, a pressure gauge (analog is fine there, but digital could also be used for safety), and a stopwatch.

Once you look into coffee forums frequented by the fans of well made coffee, you see that one really sought after thing is control and precision. Precisely controlling the grind, the amount of coffee, the amount of water, the temperature and the timing. Notice something? It's all stuff that electronics excel at, and humans suck at. Controlling timing, weight and water flow is a perfect task for a machine, which it can do with impeccable precision.

And along with that stuff, it can improve safety eg, by noticing things like "The heater has been on for a minute yet temperature doesn't seem rising -- maybe the sensor is broken". Plus quality of life thing like warming up on a timer, and automatically turning off afterwards.

The issue isn't with electronics but with electronics being applied in the wrong direction.
I guess you need me to list them. ( this is just getting funny.. telling people that cleaning their bum after number two is a positive thing.. i thought we covered this in pre-school, next up.. why you should use a washcloth or equivalent and not stick the bar of soap up your... crevices )

- smells

- dirty laundry

- Comfort (not wallowing in your own filth)

- sweat does tend to flow.. bringing with it.. you guessed it.

But onto your point about "disinfection". I don't know which alcohol baths you take, but full disinfection isn't the goal. But since you need evidence.. "How effective is soap over plain old water? It works, but all else being equal, water has a greater marginal effect. " [1]

[1] https://www.theatlantic.com/health/archive/2012/06/soap-how-...
Life at Google vs. Life at Amazon: From Hiring to Firing
Antiviral drug design, learning probable epidemic spillover pathways, immunogenetics... of course, it is still too dangerous, especially without some sort of artificial kill switch.
On the contrary: on today's candidate market company is interested to give the best offer it can afford, to close the position with suitable engineer.
And yet they still are selling the parts, despite that.
Correct. A lot of people assume that if something doesn't seem "fair", then it must be illegal. And they assume that if a company uses it's market power in some way to benefit itself at the expense of others in the market, then this must also be illegal. This goes to the idea of viewing the world as a type of HR department where you can always appeal unfairness to some authority that will punish appropriately. Many people go through life endlessly looking for an authority figure, or manager-in-the-sky to file complaints with and make things right.

But that's not how it works, you have to actually violate some law on the books, and I'm not sure what laws against monopsony we have -- for example, Apple is ruthless in driving down prices (for itself) due to its market power, and if it forces vendors to agree to never charge Apple more than what they charge another customer, this would not be illegal, even though the end result might be vendors raising prices for everyone except Apple, and thus seeming "unfair" to everyone else forced to compete with Apple. Demanding the best possible deal is not unfair competition.
I don't understand how losing the buy box for offering your products cheaper elsewhere can be anything but punishment. You say yourself that picking the cheapest price plus shipping is what consumers want, so how a companies pricing elsewhere relevant to a consumer buying on Amazon?

You're also making the assumption that the buy box always offers the lowest price, which isn't true if Amazon are factoring non-price variables like is the manufacture undercutting Amazon on their own site. So as a seller you could be offering the lowest price with the fastest shipping, but still lose the buy box because you had the audacity to offer a better price on your own site or at Walmart.

This in turn creates a very strong incentive to sell your products everywhere for the same price, regardless of your actual costs. So your prices at Walmart and your own site go up.

If pricing at other stores wasn't a factor in the buy box algorithm, then consumers could find lower prices else where if they wanted to. Thus allowing competitors to slowly loosen Amazon strangle hold on online retail, and reduce prices for consumers.

> If pricing on Amazon is too high, consumers won’t buy those products at Amazon and get rid of their Prime memberships too.

How can this ever happen if selling cheaper elsewhere loses you the buy box on the biggest online store?

> If it’s a bad deal for sellers, they can sell on other websites.

Again you're completely ignoring the size of Amazon market share here. Who is voluntarily going to give up 50%-60% of all online sales? It's a bit like US ISPs, if Comcast screws with fees stupid prices on your cable contract you can just go to a competitor right, we'll just ignore the fact the competitor is selling 2mb DSL.
I appreciate your skepticism. Unfortunately “skepticism” is basically the only credence given to the lab leak theory for the last year. Was the public intentionally mislead via the MSM? Personally I’m ready to entertain the theory because I no longer trust the institutional word.
I think it depends on what you’re doing. The author of the the Reddit post mentioned he’s primarily working with data systems. I can see the appeal of someone running quick, ephemeral data analysis not wanting to deal with static typing. But for long term use cases the static typing guard rails is definitely nice.
Are bidets meant to be used with paper or without? It seems unlikely to do a good job with just a spray.

Also, for males, doesn't genetalia and hair get in the way more, depending on the type of bidet?
Interesting, had no idea that work gloves not designed for use by NASA could cost almost $300/pair. What kind of work are these used for? Safecracking?
However, the advantage is, if it is published, it can decrease the likelihood of multiple other attempts to try the same “unique” (and wrong) approach.
I am not getting that argument, there are machines that use the same single drum for washing and drying. Its widely popular in Asia for at least the past 30 years, and I don't think they are especially succeptible to maintanence issues or it wouldn't be so popular.

Also they eliminate the need to transfer clothes from the washer to the dryer, which is a major convenience.
Beautiful Web GUI, beautiful source code, "cargo install kalk_cli" && it works like a charm! Thanks for sharing this.
FWIW, that's double the federal minimum wage. I'm mostly pointing out how absolutely absurd our minimum wage is.
So are 3G, 4G, and 5G. So is WiFi. "Proprietary" just means you need a to buy a licensed LoRa radio chip to use the protocol in a commercial product - something you can do on digikey for $5. The implementation of the protocol itself is well known and you can easily interact with LoRa devices using an SDR [1].

[1] https://github.com/myriadrf/LoRa-SDR
Even a kill switch isn't that useful. You just need a single virion to manage to drop the gene that encodes the kill switch to get your doomsday device.
Reposting my comment from the Reddit discussion,

He missed two important point that really puts me off.

The continuous reboots since Windows 8 was introduced.

The complete lack of respect for paying customers to deprecate C++/CX in name of ISO C++17 compatibility, with C++/WinRT, without any kind of Visual Studio tooling support, even after 4 years in development.

So now any .NET Native developer that would be dealing with C++/CX for those APIs that the WinDev refuses to create WinRT bindings, needs to write IDL files without any tooling, copy and merge generated files into their projects.

Wait for ISO C++ to get reflection and maybe we will do something about it they say.

Sometimes I get the feeling WinDev requires Notepad as their IDE.

Speaking of .NET Native, it is in maintenance, expect nothing beyond .NET Core 3.1 / C# 7.3.
Yes, I've started using python again with mypy static typing. I can hardly still call it a "dynamically" typed language if I do that, though.
Did you also watch: Detergent packs are kinda wishy-washy (Dishwashers Explained)

https://www.youtube.com/watch?v=_rBO8neWw04
The only interesting citation in this paper is (3) Segreto & Deigin "The genetic structure of SARS-CoV-2 does not rule out alaboratory origin" (DOI: 10.1002/bies.202000240). The other citations are political and unscientfic (1,5), scientific and neutral (4,6) or scientific and opposed (2).

Full text of citation (3) is available at https://onlinelibrary.wiley.com/doi/epdf/10.1002/bies.202000..., and a rebuttal is available at https://onlinelibrary.wiley.com/doi/epdf/10.1002/bies.202000.... Interested readers should refer to both of these articles, rather than to this strangely written summary.
> If you really want to rewire your house to mix 20 gallons of dough at a time...go for it I suppose. But do the homework first.

You could get a 3 phase commercial standby genset installed and have the remote annunciator for it mounted next to whatever monster 3 phase stand mixer in your kitchen. All in all this would run you ~50K USD.

Every day people spend far more money on way stupider bullshit than what I just proposed.
Watch this video: Detergent packs are kinda wishy-washy (Dishwashers Explained)

https://www.youtube.com/watch?v=_rBO8neWw04
Is this written by the Larry Levy from Bracewell & Giuliani (yes, that Rudy Giuliani), and who worked on Giuliani's 2008 primary bid? (That is, in addition to being vice chair of th Republican National Lawyers Association, as described.)

If so, perhaps he's a bit, I dunno, biased?

I point this out not to say that connection must taint the source, but because there have been many investigations for the types of in-person voter fraud tested here ("died, moved out of the jurisdiction, or been convicted of a felony at least two years earlier").

And they've found bupkis. See https://en.wikipedia.org/wiki/Voter_impersonation_(United_St... for many of the relevant studies and court cases.

You'll notice that real-world data should be more convincing as a pen test like the WSJ editorial described specifically excluded the estimated probability needed for a valid risk assessment.

Someone could crash a tank through my front door to grab my laptop. A tiger team might even demonstrate that on a similar building to mine. But I'm not going to install anti-tank barricades to reduce the chance that already unlikely event will happen.

Permit me therefore to remain suspicious about a WSJ op-ed piece written by what appears to be someone with a strong financial and/or political reason to cast doubt on existing election security even if that doubt is unjustified.

EDIT: The 'Alan Schulkin, came under pressure resign after he was caught on tape telling the truth' is from a Project Veritas video, see https://en.wikipedia.org/wiki/Project_Veritas#New_York_City_... :

> In a follow-up interview with the New York Post, Schulkin stated, "I should have said 'potential fraud' instead of 'fraud'". Referring to the Project Veritas operative who secretely recorded him, Schulkin said, "She was like a nuisance. I was just trying to placate her", noting that in his haste to get away from her he "was agreeing with her when I shouldn’t have been."

You'll note that Levy writes "telling the truth", but doesn't present the evidence that this is actually the truth.
I have the same experience. The only thing Facebook has figured out about me is that I like bicycling (because I post about nothing but bicycling on Facebook.) Other than that, their ads are complete nonsense.
Leveraged swaps - the kind of “futures” used in the crypto markets - are known to regulators around the globe.

The UK is fairly lax in this regard. But its nothing to do with crypto trading because this wasn't spot crypto trading.

On manipulation, eh, yay volatility. Avoid leverage in volatile markets.
A similar situation I've run into is an online store I buy regularly from that has free shipping over $X amount.

The item I buy normally costs over that but every once in a while they'll send a coupon that offers 15% off that literally drops the price to like $1 under that free shipping price.

So the "coupon" ends up making it more expensive in total because the free-shipping is based off the post-discount price.
Fascinating, I just wish the NPR audio was much longer (like hours longer)!

It felt like the intro to a podcast series (except without the podcast series).
Understood. I can't speak to outside the US, for example.

In any given moment in the US, I know people who live inside major cities, inside metro areas and in rural areas.

Of that group, the number of working folks w/ little to no work-related driving time is very small.
As Amazon's prices have risen, the minimum order for free shipping on other companies has lowered.

For human rights reasons, I am avoiding Amazon unless the price is clearly much better. The funny thing is, it usually isn't (except for books).
It's probably the talking about bidets, and how clean your butthole is, that comes across as homosexual.
Macs are not generally repairable, but some models are incredibly reliable.

I’ve been using a 2012 MBPr that still works great/is pristine, other than losing some rubber feet.

Having a user friendly OS with *nix-ish tooling in a high build quality package is (debatably) only available from Apple. I will happily upgrade to an M1 MBP once the next gen is released.
I am not a biologist and am not qualified to comment on the content whatsoever. I was just doing background research on the article I was reading and the author of the paper, and wanted to bring to light what I found.
To paraphrase what the Saudis are said to say about oil wealth: things are easy enough now to insure that the grandchildren will experience problems that used to be.