skysight-inc/HackerNews huggingface dataset:
> especially given that animal testing is not a mechanism which typically results in improved treatment.

The technique described in the article absolutely could result in not just "improved treatment", but an actual cure. We know what causes CF. We know what causes many other genetic diseases. Right down to the individual bad DNA segment.

And there is absolutely no way those treatments are ever going to be approved without animal testing. Sorry, they just aren't.
Ah okay. Thank you those in the chain.
Oh, they talk a lot about the financial benefits — lower income taxes, looser land regulations — it’s just that the personal costs of a lower minimum wage, increased sales taxes, and less educational funding from the state aren’t going to fall on the people who are driving this.
And... now?

https://old.reddit.com/r/videos/comments/ngwc3h/the_newest_p...

and https://old.reddit.com/r/videos/comments/ngwc3h/the_newest_p...
The infinitude of tokens creates an ocean of bid ask spreads and fees and other frictional costs. It is the trade off of endless horizontal expansion of new tokens each for a different purpose. It is like the 1900s when anyone who could issued their own notes or script.
> observational data show that regions or facilities with a higher percentage of the population wearing masks have better control of the coronavirus disease

Which is also not entirely true. There are quite a lot of regions (data from worldometer, statista) that have a better control of the virus despite people not giving a crap about face masks. For instance, Florida has 1600 deaths/M vs 3000 deaths/M in New Jersey. What'd be the explanation?
GCC is optimised for performing well on benchmarks at the expense of anything else. Vendor compilers for those architectures traditionally had more programmer-friendly features like trapping instead of creating an exploitable security vulnerability.
Even the worst parts of LA are miles ahead of the poor rural suburbs. There is just more visibility in LA due to the concentration of people.

In reality, the facts don't back up anything you said. :/
I used to be really into body weight fitness (actually need to start it back up again). However, they still recommend most people get weights and a set of plates because there are very limited options when it comes to doing leg exercises.
States are typically gerrymandered on the state representation (state legislature) level as well as with federal congressional districts.
My first progrmming language: XSLT.
#ouch
Students Changing Design with Biometrics
I'm just as fascinated by the valve at the base of the stomach, called the pyloric sphincteric cylinder. It uses an ingenious mechanism to selectively pass liquid and very small particles to the small intestine, while keeping larger chunks in the stomach for further digestion. It functions like a screen or filter, but with a simple, robust, and reliable structure.

Here's a fantastic (and free) book about just this structure:

http://med.plig.org/
The result is a perpetually unstable situation fostering inevitable errors when the programmer is surprised by the compiler. There's no remedy except to move away from C to more tightly specified languages.
One might argue that technically (akshually?) the Bill of Rights goes against the founding documents of USA, amending them a few years later with values that were not in the original constitution to satisfy anti-federalists criticising the initial design (and its values).
1. The first amendment gives "the right of the people peaceably to assemble, and to petition the Government for a redress of grievances." That's not the right of people to gather together wherever they want, whenever they want. Note the dependent clause. It's saying the people can join organizations like the CPUSA, People For the American Way, American Family Association, or even movements like BLM or antifa, and the government is not permitted to constrain that.

2. "Congress shall make no law respecting an establishment of religion" means the government can't say which religions are OK and which aren't, or that there's an official religion of the US. It says nothing about people being able to go to church on Sunday or temples on Saturday
It'd be nice to get some actual real-life results and this would get us there, so yeah, it'd be pretty nice if it happened.
Imagine being locked up for not paying fines, only to be fined further while your in, and unable to break the cycle...
The company has a retired NYPD commissioner on its board. Maybe people like that?

Like most "social" projects, this is about turning ordinary life into reality TV. In the second stage they make it more "interactive".

https://fnewsmagazine.com/2021/03/safety-or-surveillance-the...
Probably not, I think that would require a lot of complexity that I assume this doesn't implement (e.g. resource partitioning and time sharing).

I think the premise is just that there's not a lot of simple hypervisors available for learning. VT-x is on its own a lot to comprehend so this lets you not worry about code complexity and focus on understanding the workings of VT-x mode.
I think it's interesting that the actual proposal is RIFE with some really, really bad analysis: https://www.greateridaho.org/wp-content/uploads/2021/03/Grea...

The best example is how they treat averages: As part of their "win-win" scenario: the new average income for the state of Oregon would rise. As if individuals would actually directly benefit from the average arbitrarily going up.

Inversely, one of the benefits of joining Idaho is the lower cost of living vs Oregon, disproportionally averaging the PDX metro area as their own cost of living.

However, the whole thing is chock full of the assumption that everyone would be happier and better off if elections were less competitive. It's such a weird document in that the group is effectively arguing to gerrymander themselves into a less electorally relevant position.
In this case I'd say time is the constraint, as you want it to run consistently through your simulation. So you can't let one part get ahead or behind another in a way that breaks causality.

You are likely not running the universe on a Von Neumann machine, so compute and storage would be combined and spread out. You can't just have opposite ends of the universe interacting instantly in that case.

It doesn't have to be that way, but you can see why it would be desirable and seems to fit observations.

However, I'm at a loss how you would explain quantum entanglement if it truly is instant over any distance. That's not really known, but it's at least a lot faster than light.
If it really came to this, transfer ownership wholesale to someone who resides outside of both the UK and the EU and who isn't worried about risking UK legal ire. That way none of the current members need to be banned. (I hear Seychelles is a good jurisdiction for such things.)

Of course, the UK government might attempt to filter the website. But if SciHub is anything to go by then that might not be very effective.
To the downvoters let me explain what I meant. jancsika is an HN'er as we all are. But jancsika is on here trying to say the community as a whole is a bunch of arrogant idiots. This annoying type of comment where you make yourself seem smart by putting down the entire community has become common in this community. I see it more and more often on here.
Consider that parents may have children in their mid 40s. These children are effectively dependent until ~20. Often they'll accrue significant debt to pay for college. Then 10-15 years later their parents may need significant care. If those parents weren't wealthy or careful to save then these children could find that they've few if any years free of heavy financial or caretaking burdens. Then consider they may want children of their own.

The lack of a real social safety net in the US really feels like previous generations pulling up the ladder.
This will be an opportunity for some middleman to insert themselves. It’s normal. Crypto isn’t replacing civilization it is just another tool and will be subject to the same economies.
My Aftershokz are good for spoken word in noisy/trafficy environments unless I'm inside a car at freeway speeds, or operating a lawn mower. They could work in a car if they got a little louder.

Just be aware that they make it practical to tell that something is happening around you, but with spoken word you'll usually have to pause to tell what is happening around you. I.e., I can't understand what someone is saying to me if a narrator is already speaking into my ear.
Most of these forests are owned by the federal government. Oregon owns less than half of its land.
Out here, those rules are enforced at the county level if there's no city nearby. Counties can be massive and include lots of out of the way land.
That would be visibly inconsistent with what we observe.
Affilisites
If these people are such a drag, such a bunch of troublemakers and take in more taxes than they pay why shouldn't Oregon be showing them the door?
Yet the bounds of space are ever increasing, while the amount of matter is not.

This would only make sense if there is some weird arbitrary limitation for matter concentrated in an area. And then the solution would be uncontrollable and happen to fit nicely with the rest of the rules.
I've read that they are interested. It would extend Idaho to the Pacific Ocean and give them a seaport in Coos Bay, if certain adjoining counties in the proposal join.
1. If you're going to argue that argue that religious-provided healthcare is superior to secular, you're going to have to do better than "well, who can say." You've given some anecdata, with nothing to back it up.

2. I'm aware that conservative people consider certain procedure unnecessary. My point is that religious-based moral outrage has no place in deciding the proper standard of care. Your approach means that when your morals contradict another person's health, you get to choose what kind of services they get. That's a great reason to divorce healthcare from religious influence.

3. Being poor sounds great! Makes me wonder why more people don't move to the south and live in the socialist utopia that you describe, where everyone has all their needs fulfilled with no effort.

4. If death is just the beginning, maybe we should abolish healthcare entirely, and just get to the good part sooner. Instead of wasting money on MRI machines, heart surgery, and diabetes medication, we should instead wisely invest in elaborate mausoleum, like the pharaohs of old. This also conveniently explains why religious conservatives, although ostensibly caring about their fellow man, consistently vote against any expansion of state-provided healthcare, which is selfishly rooted in the notion of keeping people out of heaven.
Weighted calisthenics is even better. You can get huge legs doing weighted pistol squats and reverse nordics.
I'm unaware of any jurisdiction in which plastic straws are banned that does not explicitly make exceptions for those with disabilities.
I taught web development at a university last summer with CodeSandbox remotely.

Worked like a charm.
>solving IT problems on the final assessment

would love to see those
My favorite would have to be (Modular) SNUSP[1]. The combination of two-dimensional control flow with one-character recursion is completely irresistible to me. If it just had support for pointers, my life would be complete.

[1] https://esolangs.org/wiki/SNUSP
How so? The implementation can, and perhaps should, define that it errors. Whatever behaviour you're worried about a compiler doing for implementation-defined behaviour, it could do exactly the same thing if the behaviour was undefined.
Show HN: eBook Design Kit for Figma
Needs more turtles. https://en.m.wikipedia.org/wiki/Turtle_graphics
> violent criminals [...] which urban zones produce radically more of

That's just not true. A quick google pulls up this visualization from 2017: https://www.santarosa-lawyer.com/united-states-crime-map-201...

And you'll note that... there's basically no correlation with urbanity at all. Highly urban states like CT are very peaceful, but so is Idaho (but not Montana, which is pretty bad). Two of the worst states are NM and Alaska, which have near zero urban population!

There may be some rules to glean from the data, but the one you picked is not it.
>The current return is ~$1.50/TiB/Day.

I'm bearish on Chia, but I can see why it's attractive at this price point. I thought the profitability was much worse, but I did the calculations myself and it looks like around ~1.30/TiB/Day.

At the $20/TiB price point for HDDs that seems like you'd be in the money after ~16 days (excluding plotting costs and farming power usage). The big problem is the lottery, which could be smoothed out by pool farming.

Yes, the rewards are getting worse by the day, so it's hard to predict where things will be at in 16 days time, but again, pool farming should theoretically smooth that out a lot.
for future readers — ironically, there were actually WIP patches to re-implement the XUL tree (nsITreeView) using an HTML5 canvas years ago

https://bugzilla.mozilla.org/show_bug.cgi?id=441414#c172

---

"What has been will be again,
what has been done will be done again;
there is nothing new under the sun."

—Ecclesiastes 1:9

"pining for a future that never arrived"

https://en.wikipedia.org/wiki/Mark_Fisher#Hauntology
I use a similar method to share Internet with my Tandy 1000 via an old laptop I've used as a server for years. LAN via Ethernet coming in, network forwarding via iptables, and serial null modem cable to the Tandy. Unfortunately, I don't get anywhere near 750-800 Mbps but 6 Kbps :)
The [to-be-]seceding counties are strongly in opposition to the currently governing policies in Oregon, so it's quite expected that they (i.e. Oregon government and the petitioners) perceive each other as "nut jobs".
> values which are of long standing, still held by a significant fraction of the population, and them disproportionately descended from ancestors who have been American for many generations, are more American values than ones which fail one or more of these criteria

So, in an Oregon context, this would mean the values of the Chinook peoples?
Yeah I got into one with my Cuban gf and they didn't like my presence so I had to "hide".
Articles themselves are relatively rare (though they're a European areal feature, to the extent that they're added into some languages that otherwise wouldn't have them). Gender is another thing that isn't universal at all - and where it does exist, is more likely to distinguish between, say, long pointy things, humans, and non-flesh food than between masculine and feminine.
> The lack of a real social safety net in the US really feels like previous generations pulling up the ladder.

At first I misread the last word as 'latter' and I was confused because it completely reverses the meaning. English is fun sometimes.
Back in the 80s I got college foreign language credit for taking CompSci courses. I ended up taking the algorithms and data structures as well as assembly language, FORTRAN, and Prolog (in the summer). A total of 15 credit hours I think, I don't recall exactly.

In retrospect, while the courses have been extremely valuable, I wouldn't recommend programming as a substitute for foreign language studay.
Boycotting any nation is a political statement. Doesn't matter if it was employee pressure or not, it's still political.
You can go on plugshare and filter for 200 kW+ EA and see there are a huge number of sites. As far as I know every interstate site has one 350 kW cabinet.

I'm pretty sure the 150 kW cabinets are 400v. If you're there in person you can check since the inputs and outputs are labelled by law.
Symbiotic just means two species living close together. That may be positive (mutualistic), neutral (commensal), or negative (parasitism). However, mutualistic and parasitic may not be mutually exclusive. For examples, see:

1. McKay, D. M. (2009). The therapeutic helminth?. Trends in parasitology, 25(3), 109-114, https://doi.org/10.1016/j.pt.2008.11.008

2. Zaccone, P., Fehervari, Z., Phillips, J. M., Dunne, D. W., & Cooke, A. (2006). Parasitic worms and inflammatory diseases. Parasite immunology, 28(10), 515-523, https://doi.org/10.1111/j.1365-3024.2006.00879.x
But in essence putting stuff like this in the kernel is putting pressure on freezing the extension.

However it's a bit of a chicken and egg situation, you need serious testing before you can ratify and freeze but if you don't encourage people to code against the (moving) spec you wont get the testing you need.

As a CPU designer it's particularly tough, wanting those changes frozen asap so you can implement them, but not wanting a broken one
Glad they picked a simple issue where it's easy for everyone to agree on things. Presumably Apple will have an easy time resolving a conflict after the UN and US have repeatedly failed. ;-)

Given that Apple has a reasonably large R&D facility in Haifa and a fair amount of business in Israel, I don't see them disinvesting any time soon.

I could imagine them opening a Palestinian office and more stores though.
Right, because it's not like he's lied about this specific event in campaign speeches[0], or specifically asked a foreign power to assist in digging up dirt on an opponent on live TV more than once[1] or anything...

[0] https://twitter.com/atrupar/status/1310009283401187330

[1] https://www.youtube.com/watch?v=h1Q67tAUiMg
The article also suggests that the idea was in summary a bit more akin to VT-x than to vm86, but saving things in the TSS instead of a new VMCS. A fully straightforward extension of vm86 to "vm386" wouldn't work, because vm86 mostly got away with its simplicity due to the fact that 16bit x86 did not know about segment descriptors, TSSs, and all that jazz.

And in the end, long mode finally got rid of most of the segmentation, "hardware" tasks including TSSs, and other cruft in x86 that had long been abandoned (the latter at least already being regarded as a bad idea during the design of the 386). So it's probably a good thing that some "vm386" mode didn't require keeping more of that around.
The us central bank was chartered as an independent entity because policy makers here felt that having the central bank be embedded in the ex3cutive tended to inevitably corrupt the central banks decisions and led to crashes and devaluations and various bad politically motivated outcomes.
Mozilla laid off a lot of the Servo engineers. It's in the hands of the Linux Foundation, so pretty much dead.
Top PHP Frameworks for Web Development in 2021
There is no such thing as a country, just a lot of trustless interactions between sovereign mafias
10% would not be tiny, that would be a statistically huge percentage based on population counts.
Simulated jet physicists running black-hole simulations in simulated computers in a simulated universe. Imagine the horsepower. It could be 'simulations all the way down' !
Quick back of the napkin calculation shows that it is using roughly 17 petabytes (!) a month of bandwidth.
Well, the precedent would not be binding in any way - the precedent is that everyone (Oregon,Idaho,Congress) must agree, so any of them can veto for any arbitrary reason, and Oregon agreeing on these particular counties going to Idaho does not mean they would or should accept any other cases just because they vote so.
The linked pre-print[1] is very interesting - this is my first time seeing NLP content analysis and Middle Eastern studies (two fields I'm passionate about) come together like this.

The author does two analyses in the preprint:

1: Looking at passive vs. active voice (the author cites another paper that contends that passive voice is often used to obscure the perpetrators when describing unpalatable actions), they find "a disproportionate use of the passive voice to refer
to negative or violent action perpetrated towards Palestinians." So, a pro-Israel bias.

2: They find "use of more negative and violent rhetoric in
reference to Palestinians compared to Israelis." Again, a pro-Israel bias.

I think it's important to be mindful of how much math-washing[2], willful or not, is taking place in this analysis. The author mentions a few steps taken to reduce the code's bias (such as blindly tagging the keyword corpus), but even the types of analysis chosen may introduce bias. I'd love to see a few groups with different affiliations attempt similar papers and see if the same results persist.

I have trouble poking any holes in the analysis for #1 - all I can think of is challenging the assumption that passive voice reduces perceived culpability.

I think the analysis for #2 could introduce some bias, as any definition of "negative and violent rhetoric" will be subjective, but I haven't looked at the word bank or anything yet.

[1] http://web.mit.edu/hjackson/www/The_NYT_Distorts_the_Palesti...

[2] https://www.mathwashing.com/
Recompiling the kernel using profile guided optimizations[1] is yet another thing on the (never-ending) to-do list.

1. https://lwn.net/Articles/830300/
Deadliness of the virus is just a side effect of its fast spread - the major part of the spread is replication which damages the host. The virus is an optimization problem - replicate and spread as fast as you can as long as the associated host damage and deaths result in the spread decrease smaller than the gain from the replication intensity increase causing that damage and deaths.
It's not for sale, so I don't think the goal is for it to work commercially right now. This seems more like a devkit than anything else.
> given appropriate very specific input data

That's the operative words there. Compilers are not required to ensure that, in sufficiently perverse circumstances, undefined behaviour never results in demons flying out of you nose. They are, however, required to not actively put said demons there themselves, because that's part of what distinguishes a programming language implementation from a piece of malware masquerading as a programming language implementation.
There is no 'they'. We are the simulators!
Idaho has a "seaport" already, in Lewiston (across the border from Clarkston WA). You get there by way of the Columbia River and locks. I often haul giant rolls of paper in my semi from the papermill in Lewiston.
Feature phones are distinct from dumb phones. Feature phone usually implies there is a suite of built in programs. It will have a note keeping application, an image viewer/gallery view, sometimes (rarely) email, a mp3 player, a handful of games which for some inexplicable reason always includes Snake, etc.
Inkscape does it. Change the text to paths (Path -> Object to Path)
In our case (Cd'A) the majority coming in are not from Idaho moving to more urban areas...they are from out of state.

Not sure I would trust the DMV stats during the covid times too since I see a lot of unregistered/expired tags right now.

Most people from the rural areas here cannot afford a house in Coeur d'Alene...it is primarily people coming from other markets where a $600k house is considered a steal.

edit: I have lived in Cd'A for over 40 years...and this year is a very new thing.
Love this. Complete thread killer.
I see now my original comment was poorly written. I only intended to imply the SSD would be used for reverting encrypted files as part of a rolling snapshot. It would have to work in conjunction with traditional AV software to actually detect an attack. If it were actually used this way its not crazy the AV software would require the specific hardware it was designed for.

I don't think we disagree the remapping hardware could be repurposed for assisting the creation of COW snapshots, though obviously the disk space wouldn't come for free.
The Kardashians have actual jobs, though. "Celebrity for celebrity's sake" is a role the American public assigned to them, as is the role of American societal scapegoat. That isn't a fundamental role they fill, Americans just enjoy hating rich women. You never see the same degree of contempt levied at rich men.