skysight-inc/HackerNews huggingface dataset:
It does mention dogs.

No evidence the vaccine gives dogs arthritis, either. Hell is too good for the anti-vaxxers who drove the human version off the market, and for the reporters who abetted them.
> unsophisticated, underqualified

Like Lehman Brothers
I agree with most of that but I would think there are probably more, per capita, aristocrats, socialites, celebrities, and otherwise idle wealthy people today than at any point in history.
Yeah, Ukrainians only elected a hostile (to Russia) government that would threaten the viability of a major gas pipeline to Europe. These exports are basically the only real means of income for Russia. At the same time Russia would lose access to the Black Sea. Like it or not, a military's job is the preservation of the well-being of their country. If they had allowed this to happen they'd have been asleep at the switch.

Also, it's funny how all the countries suddenly wanting to change things up government-wise just happen to be on the path of major gas pipelines from Russia. Georgia, Ukraine, Belarus, Armenia. A coincidence, that. Environmentalists also spoke up about the dangers of undersea pipelines with perfect timing (see Nort Stream 2).

And so you have a country whose power structure is literally facing an existential threat. Now, maybe you think that Russian power structure really is better off disappearing into the sunset (and I may even agree with you). But to think it'll do so without a fight is naive.

This thing is bigger than Ukraine. This is a well-orchestrated multi-year operation to change the balance of power in Europe and potentially force a regime change in Russia. Ukrainians have their dreams and admirable spirit, but I think when the dust settles they will be disappointed to find themselves to have been used as pawns in a much bigger game.
How smart could whales become if they had a billion more years to evolve without having their environment destroyed by humans or some other "smart" species?
Spinach famously was misreported to be misreported to have iron due to the decimal point slip: https://journals.sagepub.com/doi/full/10.1177/03063127145356...

Nothing indicates that the decimal point error ever was made, but the account about it will most likely live a long and colorful life, just like its parent myth
> I don’t know if apartment living has changed the brains of Americans but I don’t know many guys who when hearing it’ll be/waiting more than an hour or two, wouldn’t just go buy a plunger and drain cleaner.

Your reply seems to be making a lot of nonapplicable assumptions. #1, I'm not American, so I don't know why you're ruminating about the 'brains of Americans'. #2, I know how to use a plunger and drain cleaner, my comment was referring to issues that a lay person cannot readily fix; hence the need for a repair person and the lack of ready availability of such in small rural towns.
original title: Persistent spectral–based machine learning (PerSpect ML) for protein-ligand binding affinity prediction - over the length limit but I couldn't come up with a good shortened title.
You're assuming the US and other government are not using cryptocurrencies for their own covert transactions.
we shouldn't be treating essential goods as speculative assets
> Over time, over years, pairing wore me down. Took a little bit more each day than I could recover. Until my life was working, and recovering from work, and then working some more.

This can be true of any demanding job.

Pairing is like running or cycling together. One person will be faster or have more endurance than the other. The slower one must set the pace or they will get exhausted quickly. For sustainable daily pairing, I would expect the team to quickly develop a hierarchy of speeds, with the lower speed person in every pair controlling the console.
Enjoy it while it lasts…
There is much less ingredients in digital products that can be a shortage to give away more digital products. Compared to physical ones where capacities are much more expensive compared to the price of the product, I think the parent comment is basically right.

Of course there is chipageddon now, nothing is without physical. The point is the IP and customer service are the major cost drivers, not the property, the assembly line and the workers.

One more thing is also true: you can scale up/down really fast these days and for a fact at least this won't change your price as even your scale-down risks/impacts are much lower.
Bitcoin solves this
The whole thing smells like bullshit. The idea that under a timed medical school exam a student would spend 5 minutes rooting through Canvas to find an answer rather than just Googling it in 10 seconds is absurd.

Likely the faculty was too lazy to remove the material, too tech-unsavvy to understand the possibility that Canvas could have the ability to generate automated traffic, and too paranoid to give students the benefit of the doubt.
Visualizing Garbage Collector Algorithms[2014]
Sorry, wasn't aware of that.
Not OP but Italian. Please feel free to get in touch g.costantini on gmail
The fact that it’s possible to acquire knowledge outside of university.
I guess the question is what is the cost of a "basic" standard of living. e.g. a shelter, not starving, healthcare, education. As long as that cost is low enough then it doesn't take much to guarantee it. You can certainly see some countries (e.g. Scandinavia, or Australia, or even Canada) finding a different balance point than other countries (e.g. the US). In other words, governments, regulations, unions, can (and do) influence that curve and bring it to a different (better?) place.

Competition does play some role in incentivizing people but I don't think it's the entire story when it comes to progress/improved standard of living. When 8 hour work days were introduced was there some sort of sharp drop in productivity or innovation or standard of living? Or when the work week was shortened to 5 days from 6 days? I don't think so.
I'm 35 and I don't feel any of the ravages of age that some people describe. I do exercise and eat reasonably well, but I don't think it's anything out of the ordinary. I have a desk job (programming). Am I unusually lucky? or just part of a silent majority that has nothing to complain about? Is doom just around the corner?
I'm only suggesting a possibility, not a certainty.

That said, it only takes a tiny fraction of their civilization to do it, for it to happen.
Architect Helmut Jahn dies in Illinois bicycle accident
Those are something I just randomly created.
Tangentially, is there something implicit about class hierarchy and game development? Most engines and libraries are built on deeply-nested, hard to follow, inheritance models. I read about entity-component systems, but there's seemingly no big, functionally-oriented game engines. Why? Legacy? Typical languages (C++, C#, etc.)?
Obituary in the Chicago Tribune: https://www.chicagotribune.com/entertainment/ct-ent-helmut-j...
The New Scientific Method: Identity Politics
Chinese document discussing weaponising coronaviruses
For me it is something else. Most of my career I was working as a feeelancer. And as such my main goal was always to deliver work to a certain (usually comparatively high) standard. That's just the way I like doing things.

However as a freelancer I had more or less total control over the amount and kind of jobs I would take on — now that I work in a fixed position this control is somewhat gone (or I have to learn deal with it in a different way). My goal to do work up to my standard stayed, which means there is an inbalance between the amount of work I got to do and the time I have. This also has to do with the quality of my work: Doing things well does take longer, but more importantly if people know you are doing things well a lot of things will get pushed your way.Now I could lower my standard, but in fact I'd rather quit than lower that standard.

I probably need to say no more often within the job.
And what if your child, who you save at that time, goes on to be an elite police officer specialising in child kidnappings and saves dozens of later children's lives without paying ransoms?

These situations involve complicated moral dilemmas, but thought experiments never take into account all possibilities, and at some point idealistic principles about the general problem have to give way to pragmatism about the immediate problem.

To give an extreme example, if someone had a button they could push that would end the world as we know it, and they demanded you pay them $1B or they'd push it, are you really going to argue that paying that billion dollars is the incorrect response because it would encourage future people with the ability to end the world as we know it to demand ransoms?
That's just a general problem of defining intelligence. Humans are able to excel in many different areas. Bringing domain experts here is like looking at an elephant through a magnifying glass (yep, it's just a skin patch, nothing unique here).
Status updates do not need distributed consensus or proof of work.

not the "Right tool for the job"
There are plenty of mid sized business that depend on an anchor client. Obviously that's not a great long term situation.

But it doesn't really distract from the particular dynamic we've been talking about in this subthread, which is a more aggressive and predatory version of competition that captures the deal then uses the courts to capture the already invested capital infrastructure from the side that lost the deal. This sort of tactic is enabled more by people who can market to investors via manufactured signals vs the idealized lassie faire market reality of the transaction.

I'm not pretending this is a trivial problem to solve, but I think it is very much a real problem, and the "they were fools and the market simply beat them" narratives fail to capture what's really going on here imo.
Exercise is probably the best thing you can do to improve your longevity. I don't have a source, but I don't think this is a controversial idea. Even long walks can help (though as someone who lives in the middle of nowhere, I can understand if this is not possible). I'm only 28, but I find that long walks on the treadmill (with my laptop in front of me, while I'm working) can really make me feel a lot better. I do have a general fitness routine I keep up with though, so that likely plays a role here.

One thing that has helped me immeasurably is taking up a hobby that gets me outside and doing some manual labor. I love gardening and I'd suggest it to anyone. I have shed several inches off my waistband since starting to garden and I find myself spending considerably less time in front of the computer screen just wasting time.
Related post from 25 days ago:

https://news.ycombinator.com/item?id=26816444

And for those curious about investing:

https://news.ycombinator.com/item?id=26817022
You are still comparatively young. Give it a few more years.
That’s sad, to me, but I tend to have the author’s point of view.

I support you in whatever endeavor to which your muse directs you. Having a background in coding generally means you’re a good problem-solver, and good problem-solvers are valuable in any vocation.

In my case, I was a manager for the last 25 years of my career, and was forced to do my programming as a “nights and weekends” gig. Since leaving my last job, I have been 100% focused on programming, and I’ve never been happier.

The advent of the Swift programming language has also been serendipitous. It’s proven to be fun and engaging.

My first computer was also a VIC-20.
Is it just me or is it trivially easy to get all the benefits the author describes without the downsides? Maybe just do it fewer hours for fewer days. Build in enough time for full recuperation. I'd say half as many workstations as people is definitely asking for trouble.
No, for two reasons:

1) The idea is that we will do it, not that we have done it already. (How does something we will do in the future affect what we see today? It doesn't, at least not causally. It's just that some civilization had to be first in the neighboorhod, and that civilization will be the one to preempt the others, at least according to this model. So it's more of a probabilistic conditioning effect than a causal effect: conditional on existing, that means no one preempted us, which means we're the first, which means we'll preempt everyone else.)

2) The preemption happens well before the other civilizations come into existence. For example, we might deplete their stars of energy so that evolution doesn't happen at all on their planet.
Getting Started with Computer Vision Using TensorFlow Keras
It’s just a basic thermal cycler, not a real-time one with fluorescence detectors. You would need something like a gel electrophoresis system and a transilluminator to check the results.
Interesting, as I'm getting older I realize just how much noise is out there and that I actually should be doing and knowing less, not more. A free and ready mind is an awesome resource. All the cool stuff people know? Often (not always) not that important, except as a knowledge discipline in itself / art. But I'm only in my early 30s.
If it's the one that features a line like "gin-fuelled despair", then it's the one I thought of as well.

Edit: huh, it's not. I'll try and find the one I'm thinking of.
Exactly. In cases like this using an HTML/XML parser instead of a regular expression won't make a difference at all.
The biggest benefit in my mind of rspec-given is that it allows you to combine the speed benefits of running the test setup once (When) with the clarity of granular assertions that report failures independently (Then).
1. Store any amount of money easily and securely
2. Transact quickly, easily, cheaply, globally, limitlessly
3. Nobody knows your balance
4. Nobody knows transaction amounts, senders, receivers, history
5. Nobody knows about anything you do
6. Nobody can randomly freeze your assets
7. Nobody can move those coins without the key

Have you ever had your money taken away from you? My country suffered through hyperinflation in the 90s, the government got desperate and just froze the bank accounts of everybody. The amount of disruption this caused is legendary.

It doesn't matter how much energy it consumes or how much crime it enables. If it allows us to escape government stupidity it's more than worth it.
"There's also the possibility that the existence of one civilization in a cosmic neighborhood tends to preclude the emergence of other civilizations in that same neighborhood"

Interesting. That's a point I haven't heard before. Or perhaps it's my lucky 10,000 day. :-)

Although our path through the galaxy is somewhat unique. Stars don't really move in unison in the greater timescales, but more like slip past each other. Assuming Sol was born as a binary star, its sibling could be other side of the galaxy by now.

Another thought is that if WE do expand to the stars, how long until our distant ancestors aren't really the same civilization anymore, but something completely alien to each other? Evolution could take some rather unexpected steps in the long run.
As someone who worked in an all pairing shop for two years (run by a bunch of former Pivots), I can confirm it’s pretty draining, though my experience wasn’t nearly as bad.

I actually liked pairing a lot of the time, and still think it’s an excellent way to onboard into a new code base, even in a non pairing shop (I even miss it sometimes!). For me, the main drawback after a while was that I felt like I was less efficient when pairing on stuff I knew how to do, and my personal growth as an engineer was stunted because I could always lean on a more experienced pair. Since that was my first eng gig, my second job had quite a steep learning curve as I had to figure out how to debug and navigate on my own, without talking through it out loud.
Literally half the number of workstations. No option but to pair. I would find that oppressive.
Would the Python3 version be:

map(merge_func, zip(X,Y))?
With a bunch of games requiring advanced graphic cards to emulate "retro CRT" effects on the market, it's refreshing to see software specifically written to be usable on low end machine
I have a standard 9-6 with an hour break between and then I work on a second company between 6 and midnight every night. Also work all weekends all day long but trying to have a more healthy lifestyle and go out whenever I want.

If the work is interesting I'm really excited to solve problems but I definitely don't want to do it all my life.

I'm 33yo and just trying to feather my nest.

I think I'll always work and never retire but would love to only work maybe 2-4 hours a day on my own terms
You can see this in football. In the U.K. satelite TV massively increased the market - no longer were people spending £30 a game to watch at a stadium with a capacity of 30k, they were spending £10 a game to watch on tv with a capacity of millions.

This extra cash poured into the salaries of the footballers in the top division, salary’s doubling every 4 or so years for a sustained period.

The money didn’t trickle down to lower divisions or youth training or on site staff.
We have some uninformed judgment here, don't you think?
Btw I have heard enough of Musk talk to know what's on the show. Don't need to listen to it anymore.
The word “decide” has deadly origins
LuaJIT was "good enough" at this that it worked pretty well for me -- mostly for automatically binding to headers from my own code where I was careful to avoid some of the potential gotchas. With a macro the header was stringified and sent to LuaJIT; could've also had a build step. eg: https://github.com/nikki93/cgame/blob/master/src/sprite.h#L9

An added benefit is you get ffi-reflect -- https://github.com/corsix/ffi-reflect -- over the resulting types / functions...
Right - I think we get a lot of in-built satisfaction and pleasure from being around or raising kids, specifically to offset just how annoying and difficult the task of raising them is.
This country has sooo many banks. So many. I don’t see consolidation as a big problem in the banking industry.
Exercise, enough sleep, a healthy diet, and staying hydrated can make your brain work better.

I have an intuitive sense that you have the intelligence to meet your goals, so the keys will end up being focus, drive, the ability to stay with it when the going gets really rough, and the humility to ask for help when you need it.
> he has been called a Nazi apologist

Here is more on that topic, titled "Exposing Jordan Peterson’s barrage of revisionist falsehoods about Hitler, the Holocaust and Nazism"

https://www.haaretz.com/world-news/.premium.HIGHLIGHT-jordan...

Non-paywall version at https://theworldnews.net/il-news/exposing-jordan-peterson-s-...
The British elected a hostile (to the EU) government. I have yet to see French or German tanks roll in to British territory.

It's their country. It's their right to decide whether they want to have gas pipelines there. That this is an existential threat to Russia is kind of a problem of their own making and, quite frankly, not Ukraine's problem. Don't bully 42 million people because you can't solve your own problems.

You do realize what you're advocating for is that Ukraine should be a Russian puppet state?
Then again you can create new cryptocurrencies out of thin air.
Ransom ware seems like a potential antidote to vulnerable US digital infrastructure. It provides a persistent, material bug bounty which incentivises the C-suite to fix them.
Trouble at Basecamp – Destruction of the holding environment
Scheme is a language where I wish this was part of the spec. So many Schemes are intended to be embedded or extended with C, and every one of them has a bespoke way of declaring C bindings and martialling data between C and Scheme.
> I don't know why you're ruminating about the 'brains of Americans'

Because Americans often seem to have a fascination with living in shoe-boxes and divesting themselves of any personal responsibility for things like this.

Homer Simpsons "can't someone else do it" attitude, effectively.

> my comment was referring to issues that a lay person cannot readily fix

There aren't that many things that can go wrong in the home, and that you would expect a person to come and repair, that you the occupant, can't also repair. Yes you will possibly need to learn something new. Welcome to life.

A blocked toilet is most definitely one of the things you can fix. Calling a plumber for a blocked toilet is like the oft-quoted calling IT support for the unplugged computer.
Personally, I think "intelligence" means different things to different people. Some people are intelligent in their specific domain because they spend a lot of time working in that domain. Others are generalists, they know a little bit about a lot of things. To me, both are intelligent in their own right.

This article had a huge impact on me: The T-Shaped Information Diet - https://junglegym.substack.com/p/the-t-shaped-information-di....

Here's the basic idea:

> The T-shaped talent model suggests that the best way to grow your abilities is to build a shallow understanding across a breadth of domains and a depth of expertise in whichever domain is most relevant to your profession.
> That is of course not true. Individually curated means synchronized with others as no individual exists in a vacuum ... That it is free to evaluate its own future path

You misunderstand. The question is whether individual value structures converge/approximate to a superstructure outside every individual, not whether individuals can use environment, history, each other etc as an inspiration for their custom tailored lives. The sense of the former was destroyed with the end of modernism. Everything dissolved in an acid vat of infinite relativism. Every normativity other than growth in the market got destroyed/crumbled. And individual achievement is merely the projection of that at the atomized level.

> Achievement in itself is, unparadoxically, and achievement. That you don't agree with it says more about your synchronicity with the rest of society than the opposite.

I take that as a compliment because one of the things I aspire to is to not get dissolved in the blind allegiance to achievement and excess positivity. It usually gets unnoticed but when people excessively project themselves to achievements and future growth; they turn into massive narcissists. And I am not using that in the pejorative sense; they lose a grounded sense of themselves. The freedom from "improving", being able to have leisurely, contemplative time, enjoying "returnless" social encounters for their own sake, having a sense of limits etc counter that. I wish they were valued more.
Top model iPhones have increased price about 15% per year since launch
> 6-8 plants are needed per person to endure if there is no air circulation (significance you can stay in a completely air covered area if you had these plants).

I'm trying to decipher what this means, but just in case someone thinks it means you can survive in a sealed room with only 6-8 of these, without exposing yourself to significantly higher levels of CO2, I don't think that's possible.

Further information:

https://en.wikipedia.org/wiki/NASA_Clean_Air_Study

https://www.youtube.com/watch?v=PoKvPkwP4mM
How to nuke AWS resources and save additional AWS infrastructure cost?