skysight-inc/HackerNews huggingface dataset:
"Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism.""

Everything you have said is true.

What I think you are missing is that there is both a per-calorie inflammation cost for all food inputs and a minimum inflammatory startup cost just to metabolize at all.

More simply: 1000 calories spread across two meals will generate more inflammation than 1000 calories in a single meal.

There are two analogies that I think are useful when thinking about this:

First, introducing food inputs appears to be an interrupt for most other bodily activities - even very essential ones like sleep and reproduction, etc. You might consider how many hours each day your body spends not digesting. It doesn't take much to increase that by 50% or more...

Second, electric motors like pumps and fans have failures ("deaths") that are much more accurately predicted by number of start-stop cycles than by the number of hours run. Startup is expensive for these devices and I suspect that startup is expensive for our food metabolism as well.
I think a less pot-stirring way of saying this is to just point out that most US colleges/universities are closer to Fachhochschulen than Universitäten.

The difference between the two regions is IMO mostly overstated. Especially in CS. Both the US and EU have institutions with trade school-style CS bachelors/masters as well as truly top research institutions with real Computer Science bachelors/masters degrees. Saying much more than that isn't particularly helpful.

NB: I'm willing to bet that most of the "hard core science" teams in Europe have Americans over-represented relative to other teams in the company. This says more about how immigration systems work than anything else.

Also NB: being on "hard core science" teams isn't the best way to maximize income/career trajectory at FAANGs, and isn't even the most secure... remember a buncha years back when Microsoft killed off its bay area research lab?
> We conclude that inflammation is an important malleable driver of ageing up to extreme old age in humans
One thing to note is that the purpose of ads might not just be to get you to directly click on it and buy something. It might also be to make you remember the brand name so the next time you think of lets say baby diapers, you remember "Huggies" because they are the most advertised ones even though there are better and cheaper alternatives.

As for how impactful the ads are - you don't need a study. Simply run an ad and you will know how many people click your ad and how many then follow up with purchasing. That's where terms like cost per acquisition (CPA), customer acquisition cost (CAC), cost per click (CPC), Cost Per Thousand (CPM) etc come into place.

https://www.investopedia.com/terms/c/cpm.asp

It's not one purchase per billion ads. You can look up google Adwords cost per acquisition by industry (WARNING - might be blocked by ad blocker):

https://www.wordstream.com/blog/ws/2016/02/29/google-adwords...

Cost per acquisition on the app stores is much cheaper too.
it doesn't say that anywhere indeed, but this is my understanding: if you reload the page your login is being preserved without re-entering your password. there's no way to maintain this without storing a key on the server (i.e. either the master key (MK), or a key that encrypts the MK, if the MK is stored locally
Thanks for posting! It checks most of the boxes for me. I've been using Simplenote which is perfect and minimal for note taking. But when I start to blog I find the lack of live preview and spellcheck inconvenient.

Looking forward to the desktop apps and possibly offline support!
308,583 in the last 24h.

https://bitinfocharts.com/bitcoin%20cash/
> I believe i represent the views of a silent majority in india.

Correct me if I misinterpreted what you've written, but if you think removing diversity is what the "silent majority" wants, boy, are you living in a delusion. You might be trying to make up explanations to forcibly rationalize bigotry. Ethnic and religious diversity is not something you can just turn into "homogeneity" without large-scale genocide. Besides it was never a significant factor in Japan and China's growth relative to India.
HTTP CONNECT tunnelling works even with HTTP 1 though, it just might work more efficiently with QUIC. So it could be a seamless fallback.
Have you tried to write an X.509 DER PEM file parser? I started one. Just reading the specs (X.509, ASN.1, DER, & PEM) takes two days. If writing a JSON parser is a walk down the block, then writing an X.509 cert parser is a marathon.

How is TLS modular? It mixes encrypted and unencrypted message types [0], leading to implementation vulnerabilities [1]. It contains many unused and unnecessary features and extensions, some of which are very bad ideas (renegotiation, client_certificate_url). We all deserve a good protocol to protect our data and systems. The complexity of TLS helps the incumbents, stifles innovation, and harms privacy and security.

Many organizations spend a lot of money and effort to upgrade software and prevent obsolete software from running. This will become a bigger need in the future as ransomware attacks become more common. Building mandatory upgrades into an Internet protocol would take boldness and courage. The benefits will accrue to everyone in society: Less of our data will get stolen by criminals and spies. Fewer organizations will get extorted by criminals. Fewer hospitals will get shut down.

[0] https://tools.ietf.org/html/rfc8446#section-5

[1] https://mitls.org/pages/attacks/SMACK
The same anti-web sentiment appears on nearly every post about a web app (app in the traditional sense "app", rather than a web site like a blog or something) and I do not understand why it won't die. The market has spoken for years that it prefers web and mobile to native desktop for everything except games (and even gaming is rapidly becoming a mobile-first segment).

The question we should be asking is: why would anyone want a traditional desktop app? Why are we investing in traditional apps? Who in the next few generations is going to even be familiar with much less want to use desktop apps!?
Fair point. I see what OP means now. Though that is like saying one won't use React Native or Flutter because it's made and funded by FB and Google.
A little bit Poe's Law there, but I'll assume you're serious and point out the problem.

Machine learning has non-trivial false positives. We don't need firewalls launching denial of service attacks on legitimate traffic at random.
> This is done by examining whether there is evidence that countries that relied most heavily on slave use in the late 18th and early 19th centuries are poorer today.

How would this ever apply to the country with the largest economy by the turn of the 20th century?
I wish this trend to start articles with 'tl;dr' would stop. Opening with a summary paragraph predates the attention-deficit/time-starved age by many years, and is not an innovation.
Sure, but in order for this first world perspective to hold, you have to pretend that properly developed WordPress themes don’t exist.
A related read: "Against meatposting"

https://heated.world/p/stop-meatposting

"Meatposting is free PR for a high-polluting industry"

It's like posting a photo of you filling up your gas tank and tagging it "Hell yeah, gas!"
As an engineer/wantrepreneur, Whenever I go to TechCrunch, I feel FOMO. It seems like all they care about is touting large valuations and creating hype around them. At the end of the day, they think that is news-worthy.

I prefer IndieHackers, atleast it's made for entrepreneurs for antrepreneurs and gives some useful advice. TechCrunch is written by so called "experts" who have no experience with tech or startups. Their journalists mostly just have experience writing clickbait.
The article has been updated to avoid calling the bytes "not useful" and to address the narrow, specific points I raised, but it is still generally suspect.

Over on Lobsters, zeebo took the time (thanks!) to build the same version of CockroachDB with various historical Go toolchains, varying only the toolchain, and found that if anything the Go executables are getting smaller over time, in some cases significantly so.

v1.0 v20.2.0
1.8 58,099,688 n/a
1.9 57,897,616 314,191,032
1.10 57,722,520 313,669,616
1.11 48,961,712 233,170,304
1.12 52,440,168 236,192,600
1.13 50,844,048 214,373,144
1.14 50,527,320 212,699,656
1.15 47,910,360 201,391,416

https://lobste.rs/s/gvtstv/my_go_executable_files_are_still_...

The title of the article ("My Go executable files are still getting larger") appears to be literally untrue, at least read as a critique of Go itself. If they are getting larger, it's because new code is being added, not because the Go runtime or compiler is degrading in some way over time.
This is somewhat ironically a pretty depressing comment, because it implies that the overall community genuinely wants Bitcoin to have the technological characteristics it currently has.
I'm sure you could solve that with some kind of pulley system.
> There is no performance gain in going from Python to C++

The backend of TF/PyTorch is written in C++ anyway, so the more complex the model, the less time it needs to spend in the glue code (frontend) that is written in Python. Therefore, rewriting complex models in full C++, for example by using TF/PyTorch C++ API, probably won't much improve the performance.

In this paper the author rewrites some ML models in Rust using tch-rs (Rust binding for PyTorch C++ API) and finds the performance not that much better (even some models perform worse):

https://www.aclweb.org/anthology/2020.nlposs-1.4/
chasing TC was never the goal, prometheus > zeus
does it use neqo? https://github.com/mozilla/neqo
I feel a take that takes apart a whole comprehensive notion, one that is sure to have many rough edges, is nitpicky and worth little. So, I will try to address your points (for my own benefit), and then---perhaps---lead into a more worthwhile discussion.

> The formal definition of rational actor is not nearly 150 years old. It's heyday was probably in the time of Becker, in the 70's. The study of equilibrium refinement concepts practically died before the 90's, as did General Equilibrium theory (actually before that). The straw man has seen better days.

I believe you missed the point. Arthur was discussing the phenomena's overall history, not its formal comeaboutance. I.e, "economic theory has viewed agents in the economy (firms, consumers, investors) as perfectly rational decision makers facing well-defined problems and arriving at optimal behavior consistent with — in equilibrium with — the outcome caused by this behaviour." not "economic theory has specifically labeled its views that agents in the economy (firms, consumers, investors) as perfectly rational decision makers facing well-defined problems and arriving at optimal behavior consistent with — in equilibrium with — the outcome caused by this behaviour."

> Is it fair to converse with academic literature that is 40 or more years old - as the author does when referring to the "standard model of financial markets"? Perhaps more relevant: Is is useful?

Nay, I say. Literature (even more specifically scientific and technical) starts to become unintelligible nonsense after the 1950s. This is true for economics, as it is for any other discipline that was long-standing before this time. We are starting to see a reversal -- and some sense is coming back to academia -- but it's simply the beginning of the rise, and not worth mentioning.

Frankly, I have lost the will to continue (it is a Friday night, after all). But, do you see merit in the two points I've made so far?
100% agree, I think a lot of people became disillusioned about the state of things and many have lost quite a bit of faith in their governments and elected officials. That said, I wonder if people will just forget it all once things return back to normal, whatever that normal is.
Yes. TV advertising is actually much more targeted than web advertising. (In the sense than TV advertisers know precisely their target audience and its response.)

The various annoying remarketing schemes are a tiny part of advertising technology and really only exist because of the well-meaning but poorly thought-out ideas about privacy on the web.
AWS has failed at this numerous times. A company filled with a large number of incredibly smart, incredibly capable engineers who have routinely failed to notice certs were about to expire etc. Amongst organisations with operations teams obsessed with uptime, and an obsession about measuring and monitoring everything.
I sat through so many internal incident reports that boiled down to expiring certificates there.

Since I left, I understand that they've fully automated, and mandated, all certificate generation and rotation, but there have still been cert expiration events, albeit rare.

Cert expiration events happen. It's zero indication of the intelligence or capability of the engineering skills or maturity of a company. It's a thing that just works until it doesn't, with zero warning.
The opening line of the 4,000 year-old Sumerian poem "Gilgamesh, Enkidu and the nether world":

"In those days, in those distant days, in those nights, in those remote nights, in those years, in those distant years; in days of yore, when the necessary things had been brought into manifest existence, in days of yore, when the necessary things had been for the first time properly cared for, when bread had been tasted for the first time in the shrines of the Land, when the ovens of the Land had been made to work, when the heavens had been separated from the earth, when the earth had been delimited from the heavens, when the fame of mankind had been established, [...]"

Even the people of 4,000 years ago were romanticizing the ancient past!
Also in front of the scenes: the largest country with the smallest population. In the world. Giving a Canadian cell access costs 6.5x more than it does to provide ab American the same service. Why would the prices be even close?
Just watched the Father Goose following your recommendation and came back to say thank you. Marvellous movie.
About 5 years back they were going through a spell of getting lots of engineers from AWS to join them, offering way more than Amazon was. Some of the smartest and most capable systems engineers I know headed in that direction.
Armchair opinions will be armchair opinions.
Yes, and 99% of the world aren't coders, so that's why Squarespace is so popular.
> There are probably battle tested implementations in e.g. Python, Java or other safe-ish languages to build on?

My experience... there aren't a ton of choices in this space. There are a few FTP servers designed to power B2B backend services. Many of the options are designed only to provide access to the local filesystem.
‘Things’ in Fiction Shape the Way We Read
It is not hard to set up openvpn in TCP mode and running on port 443 you know....
Though I think it’s too late for other coins to fix this and present themselves to be an alternative; Bitcoin has already grown too big (too much trust & resources spent on it globally), and the failure of Bitcoin will probably mean the failure of crypto as a whole. So Bitcoin itself needs to actively fix this deflationary problem for crypto to be used as actual currency. The problem is most believers of Bitcoin want it to stay it as deflationary (as most are just speculators), and only a minority are really seeing the problem here...
I'm suggesting that, if you're unemployed, you can literally do anything. With or without money you have the power to change the world. So what you choose to do with that freedom says something about who you are as a person.
I wonder if geography or population density matters in these conversations. It costs 6.5x more to bring a cell tower to your neighborhood than it does in the US - but you will continue to compare Uganda or other countries that are postage stamps in terms of size compared to Canada - and act as if that’s logical.
Why?

Cost and regulation, but even if it was cheaper and unregulated it`s a terrible technology for electrical generation. It`s an over-hyped steam turbine. You heat shit up real hot and then turn a wheel. That`s it! It`s laughable and with the addition of being massively dangerous to human health and then all those other additions such as cost, etc. Nikola Tesla was producing electricity with metal plates and hand built capacitors in the 20th century for cheap and people think we need a nuclear plant to produce electricity for a nation? Give me a break. Ridiculous, just ridiculous.
Outside of physics, a single study with a surprising result is usually wrong.
Is this Linux under the hood?
If you simply obey the standard, everything works perfectly well. For example, the only standard way to build HTTPS middleboxes is to fasten a standards compliant client and server together, when a corporate user tries to visit google.com the server presents them with its Certificate for google.com from your corporate CA, and the client connects to the real google.com, now the flow is naturally plaintext inside your middlebox and you can do whatever you want.

If you did that, when TLS 1.3 comes along, your middlebox client connects to google.com, the client says it only knows TLS 1.2, google.com are OK with that, everything works fine. When the corporate user runs Chrome, they connect to the middlebox server, it says it only knows TLS 1.2, that's fine with Chrome, everything works fine. The middlebox continues to work exactly as before, unchanged.

So what happened in the real world? Well of course it's cheaper to just sidestep the standards. Sure, doing so means you fatally compromise security, but who cares? So you don't actually have a separate client and server wired together, you wire pieces of the two connections together so that you can scrimp on hardware overhead and reduce your BOM while still charging full price for the product.

The nice shiny Chrome says "Hi, google.com I'm just continuing that earlier connection with a TLS 1.2 conversation we had, you remember, also I know about Fly Casual This is Really TLS 1.3 and here are some random numbers I am mentioning"

The middlebox pretends to be hip to teen slang, sure, pass this along and we'll pretend we know what "Fly Casual This Is Really TLS 1.3" means, maybe we can ask another parent later and it sends that to the real google.com

Google.com says "Hi there, I remember your previous connection wink wink and I know Fly Casual This Is Really TLS 1.3 too" and then everything goes dark, because it's encrypted.

The middlebox figures, well, I guess this was a previous connection. I must definitely have decided previously whether connecting to Google was OK, so no need to worry about the fact it mysteriously went dark before I could make a decision and it takes itself out of the loop.

Or worse, the middlebox now tries to join in on both conversations, even though it passed along these "Fly Casual This Is Really TLS 1.3" messages yet it doesn't actually know TLS 1.3, so nothing works.
The comments here prove their marketing could use work. SN Extended is basically a completely different app than the free version. Nested folders, smart tags (i organized a workflow with untagged notes going to an inbox folder, notes with due:yyyy-mm-dd being pulled into a Next Items folder etc..)

Also there is a markdown editor, an editor that encrypts and stores attachments in an S3/webdav/drive/dropbox folder. There is a simple spreadsheet editor as well that I use for simple personal sheets.

None of this you would really internalize on a cursory view of the homepage or by really even downloading the free app.
> It's all conjecture.

That's incorrect. It's about timing and managing public opinion. Saying they haven't died yet (or deaths not being attributeed), is a matter of PR. Splitting hairs is hand wringing of the highest order. I hand you a pellet that emits 30rads and you throw it away, but have blood disorders and hemorrhages in 6 months that ultimately kill you...was that not an attributable death?

The radiation has had a measurable effect, eg http://www2.ans.org/misc/FukushimaSpecialSession-Caracappa.p... which will not be attributed because of a lack of ability to directly correlate individuals and cancer sources via modern methods (most importantly, for liability purposes), not because there is an uncertainty about the result of such exposure in a population. It's not 0-1 deaths.
Not sure where you got the question marks from, but he's talking about ellipses (two or three periods in a row, like '...'). It's actually a stylistic choice and there's nothing inherently wrong with using it, but it is generally considered unprofessional and overuse is extremely annoying for readers.
Will Trillions of “Printed” Dollars Cause Inflation?
Sir Malcolm is the stone cold nuts.
Empathy is very much a learned skill. "Pretending" to care is a good way for me to get someone's attention and learn a bit of their story, and then find something to relate to.
Heard instinct: Deafness and the prosthetics for overcoming it
Ask HN: You have a fortune of $100B, how would you fix earth in 3 years?
I would figure out how to cover each of the great lakes in algae (chlorella vulgaris), as they are the most efficient natural way we have of capturing CO2, and create a fund to pay off everyone who can validate having a business dependent on fishing in the great lakes for 7-10 years to make them quit talking. I would move whatever unique wildlife there are there to other lakes too because people would complain.
only short term via cortisol, long term burnout is as mysterious as it is destructive
That's because underneath there's a primitive Bayesian engine with a simple rule of

P(buying crap on the Internet) < P(buying crap on the Internet|already bought crap on the Internet)

there's nothing intelligent going on under the scenes and a massive tracking setup isn't needed here.

(And yes, the massive tracking by Google, Facebook et al isn't really for advertising purposes. It's so they are prepared to pivot from adtech to the much more profitable govtech, a la China's social credit system. TV advertising is actually much more targeted than web advertising and they do it with practically no tracking at all.)
Anecdote: Last year my girlfriend recently became obsessed with BBQ and has been smoking brisket using technique #4 for the past month. It's consistently improved the brisket every time.
This is just a joke but quite comically my Twitter account was recently restricted (basically banned, cannot even modify own settings).

The account was setup to follow companies for special offers. There were only a handful of tweets in the lifetime, all related to very simple product questions.

I cannot reach a human, but I guess I paid nothing so I get nothing. Given that the account was just used as RSS+ I could easily create another, but I just didn't want to be bothered to create new accounts.
Again, they are serving in the most powerful legislative body on earth. Putting retirement savings on hold is an extraordinarily small request given the amount of power that even the lowest-ranking Senator yields.
I own several Texas BBQ restaurants

You, sir, are a hero. mostly for the brisket though, not any of the other stuff. Which brings me to your point #1: You are correct, but leave off an important fact: No matter the grade or source, if properly cooked there is not such thing as a bad brisket. There are merely lower grades of amazing.

My primary complaint about brisket is that somewhere around '07/'08 people started realizing that a properly cooked brisket was the most underrated piece of meat on the market. This drove the prices form $2-$3/lb to north of $8/lb.
I defaulted to “lie-chess”, and that’s where I’m staying.
Never heard of class A vs class B shares, can anyone please explain? TIA
Yes, that's another great reason to fail promptly.