skysight-inc/HackerNews huggingface dataset:
HIV does not generally infect the germ cells that produce sperm or eggs, so it is not heritable, which is maybe the sense you interpreted OP's comment.

Still, HIV is a provirus. Retroviruses write themselves into the genome of the host cell. Cells which are infected and survive to reproduce carry the HIV provirus. As will their descendants, and so on. They will produce HIV when mature even without any HIV particles in the cell. This is integration with the host genome.

This is why HIV cannot be cured with antivirals which fully inhibit its replication. It's also why complete destruction of the immune system (in the process destroying all the cells which are the specific hosts) while flooding the body with high dose antivirals, and then grafting innately immune T-cells, is an effective, if rather drastic, cure.
> the future proof

No, not that.
If you are going to use Bayesian probability, you need to assign a prior probability. And the principle of indifference is the simplest non-informative prior, so it makes sense as a default choice, unless one has some good reason to choose a different prior instead.

Using a subjective Bayesian approach, in which Bayesian probabilities are just an expression of your own subjective judgement, you can choose priors on subjective personal grounds such as your intuition, whims, or desires (what you want to be true). By contrast, in objective Bayesianism, we need to provide some objective rational justification of the prior we choose, in which case it is hard to justify any initial prior for the simulation hypothesis than 0.5.

Does it really "implicitly assume more knowledge than we actually have"? To assign an epistemic probability of 0.5 exactly to a proposition is to be in a state of zero knowledge concerning its truth. As our knowledge moves away from zero, epistemic probability moves away from 0.5 and closer to either 0.0 or 1.0. To assign an epistemic probability of 0.5 exactly is to assume no knowledge at all.
5 years old not knowing all the letters or not knowing how to read does not strikes me as odd or catastrophic. That is what first grade is for.

But it gives me some idea about why the amount of parents who think starting school a year later might be good idea for their kids.
I actually belive that, yes, because you and your entire family will not stay isolated for 24 hours per day.
Interesting. It looks very nice!

I could imagine mixing in "normal" polygons with this approach may not be trivial, though. I couldn`t find much information about this circular projection online, some napkin-math tells me that straight lines in world-space don't project into straight lines in screen-space. just drawing a triangle is not trivial.
https://academic.oup.com/jcem/article/106/3/e1343/5934827

https://www.medrxiv.org/content/10.1101/2020.09.04.20188268v...

(Also, thanks. I didn't realize the one you cited as retracted, though there's some nuance there too.)
Absolutely. I think we're in total agreement here. I don't think parents should be lauded just because they produced offspring but I am learning about the process of delivering a child and it is probably one of the most frightening and painful experiences out there. Kudos for going through that is warranted, but raise yo damn kids!
I'm impressed this works so well on mobile.
Setting covid aside, if there’s a water bottle machine next to a high quality free water dispenser, why would people pay $1 for a bottle?
I don't think the little guy that's calling you cares that much, or that the organization that runs the call center is organizaed well enough to receive a piece of information from the bottom end employee and act on it.
Facebook still may have your phone number if a business uploaded your phone number for targeting.
World’s largest two wheeler factory
They are fast only on fast and expensive user equipment:

https://infrequently.org/2021/03/the-performance-inequality-...

More context in older post:

https://infrequently.org/2017/10/can-you-afford-it-real-worl...

> Partner meetings are illuminating. We get a strong sense for how bad site performance is going to be based on the percentage of engineering leads, PMs, and decision makers carrying high-end phones which they primarily use in urban areas.
> Otherwise this is just another way to add barriers.

Personally I think pretty much everything in GDPR is just sensible guidelines for how to handle personal data, and if you're not willing to do those things then you probably shouldn't be handling personal data in the first place. Being ignorant of good data practice is not an excuse.

> If you are on modest income you can forget about setting up a website in the EU.

This is just rubbish. GDPR only applies to personal info for a start so if you don't store personal info then you have nothing to worry about. Even if you do store personal info the vast majority of use cases are really straightforward and require a very minimal understanding of the law to be compliant.
The mid rises were built because the rich people were moving to transit oriented areas, not the other way around.
> Want to costume a princess to feel sweet and feminine?

You are already starting with "I want the princess to be cartoon character rather then human character".

Also, presumably, there would not been a single viking with bright pants, but rather all characters having colors. So one wiking would stand out less.
Seems weird to have specific keys for à é è when you could just combine them e.g. '+a '+e as is the case in the US international keyboards. Ditto for ç
That’s assuming that they have a truly L4 system. I don’t think it’s that simple. Danger can go from 0 to 100 fast in a car. There are so many corner cases that it isn’t hard to imagine a few stacking up and serious accidents happening.

That Phoenix, with its very clear weather, is the only market with their taxi service is damning.
Intercepting at line rate isn't a thing. Recording absolutely happens, but that's why we're talking about End to End Encryption. It would suit snoops very much if what they recorded wasn't 90% unintelligible noise.

Right now they get a good idea which sites are visited (because of Server Name Indication) by web browsers, and they get some portion of email (sent in the clear) plus a small fraction of web traffic (HTTP-only) and numerous older unencrypted protocols.

In particular they also get most of DNS. DPRIVE work (DNS over TLS, DNS over HTTPS, and eventually DNS over QUIC) reduces that considerably. Future DPRIVE work also includes oblivious transfer (you ask say Google to do a DNS lookup on your behalf, they learn who you are and which DNS server was asked but not what you asked it, the DNS server learns what was asked but not who you are, you get your answer).

Or of course, if you're particularly worried, you use Tor and everything on the snoops' screens dissolves into noise.
FBI Confiscates Safe Deposit Boxes in Beverly Hills
There are two issues in your reasoning.

First, you're assuming that they own the place outright. That wasn't the case for the immigrant in the top level comment.

Second, you're making the bizarre implicit assumption that the market for buying housing and renting it are fully independent, which couldn't be further from the truth. Increasing real estate prices contributes to an increase in demand for rent, as less people can afford to buy housing and must rent, until there are no more would-be homeowners that can't afford a house and must rent.

Those units are getting sold, one way or another. They're either getting sold to a landlord or a homeowner, so until there aren't enough units for rent for people that don't want to buy, and we are very far from that, it being sold a landlord means one less homeowner.

By the way, this is a huge issue in New York City - landlords that have a mortgage, like the one the OP had mentioned, can't afford to lower rents because that would break their mortgage agreements and force them to renegotiate it which they can't afford, so they would rather keep vacancies than rent at lower market rates.

Otherwise, if someone adds actual housing supply then it can be worth increased systemic risk. If they aren't, there is no upside to the downside.
It should be the other way. PDF ought to die and let documents be parsable
It’s been a few years, but I’m pretty sure both our kids could read multi-syllable words entering first grade and had spent a lot of the summer reading on their own.

It seems like that one year difference will get kids tracked with “the smart kids” and that gap will likely widen rather than narrow over the years.

It’s not catastrophic, but it does seem like it’s at least relevant, and possibly important.
I find a lot of private schools are trying to justify their fees by offering “virtual learning” which is just a teacher trying to apply in-person techniques in front of a camera, and then a parent struggling to keep the child interested in the (non-interactive) screen. This is doomed to failure and entirely unnecessary and pointless at the kindergarten level.

Also if the parents really want to and help the child, it’s entirely possible for them to be reading, counting and doing basic math by age 4.
I wish that systemd was only a replacement for init scripts. I feel like it does a nice job at that, its become a lot easier to deploy a new daemon when compared to writing a robust shell script for each daemon.

On the other hand the logging, cron, network interface management, etc features of systemd I could live without. I can understand why they are there on paper, but IMO they don't actually need to be centralized in systemd. I would prefer some separation.
"Bigger", as in IMAX, did not come from Expo 67. It came from a long line of attempts to make really wide screen films. Cinerama (1952), Todd-AO (1953), Cinemascope (1953), etc. The really wide screen systems required custom theaters and very elaborate machinery, and never really caught on. Cinemascope requires just a lens adapter for an ordinary 35MM projector, and it went mainstream.

What to do with widescreen cinematically was a big problem in the early days. Roller coaster demo reels introduced Cinemascope [1] and Todd-AO.[2]. 3D was tried in the same time period. Theaters were trying to do things TV could not do. But how do you tell a story on a huge screen without the screen getting in the way of the story? Most of the time, the screen won. (See the ending of "How the West Was Won" (1962).[3]) Michael Anderson (Around the World in 80 Days), not Kroitor, seems to be the director who figured that out. You make big-budget spectacles, with a plot in glorious locations. Ben-Hur and Cleopatra followed.

That's still the problem with IMax. The giant screen wins over the story.

[1] https://player.vimeo.com/video/266574534

[2] https://youtu.be/MU76gdjr-Dk

[3] https://youtu.be/8t_qToyqiOU?t=76
That changed in 2012:

https://netsplit.de/networks/top10.php?year=2012
They developed a piece of mRNA that produces a specific type of blood protein that binds the HIV infection mechanism. The bound protein triggers your body’s antibody cascade to attack and neutralize it.
My current problem is that it takes about one minute to configure networking on Ubuntu after waking up from sleep on my workstation. This is s problem with systemd and network manager.
I don't have it as such but would prefer something quicker.
I wonder why browser bookmarks don't save the position.
Show HN: Map of active customers for landing page
I used to be a die hard Ubiquiti fan.
They have fallen from grace in a big way. Disappointing.
GitHub Actions being actively abused to mine cryptocurrency on GitHub servers
Opera does better, or at least it used to.
I'm not sure how to interpret the results that returns. Can anyone summarize?

Also, I have heard rumors that the only things recorded as adverse reactions to the vaccine are things that begin in the 15/30 minutes before the person leaves the vaccine facility. Can anyone confirm or refute that?
I agree, but Jackson is on the $20. We can evaluate the art separately from the people who made it or the people depicted by it, much like how we can play with TempleOS without endorsing its author’s racist views.
Yes your original reply was, but this specific childthread is talking about Denmark and how stopping the AZ vaccine pushes back their estimates by two weeks. This will likely cause preventable death in Denmark but those numbers are not in the thousands.
This is half clever, but taking up the other side of that bet in a public market would immediately make you a person of interest to law enforcement.
Scop – a 3D model viewer written in C++20 and Vulkan
Vaccines trigger an immune response, preparing the body to fight of the infection. This allows the body to "beat" the infection before it takes hold.

Afaik vaccines are not useful after the fact. I.e. this HIV vaccine won't be given to people already infected.
Remote’s a disaster for little kids, and about as much work for one or both parents as just teaching their kid some stuff themselves. If you don’t need special reading or speech intervention then well-chosen apps and a workbook can replace most of the useful actual instruction in kindergarten. Maybe just YouTube how to teach the alphabet correctly for phonics and you’re golden.
> more salmon than we know what to do with

Bury them in the ground as fertilizer?

Requires people to fish them up, but maybe we can redirect some of the effort that goes into overfishing to that.
So, what happens now? Will Ubiquiti be held to task, by anyone?
They’ve lost my business.
Anyone know of an equivalent for linux?
There's far to much phosphate sludge for me to tackle. I don't have access to that much lye.

Anyway, far brighter minds than mine have been looking at for at least fifty years...Florida got serious about phosphate ecology and water quality in the 1970's. The gypsum stacks and sludge ponds exist because of water quality regulations not the good will of industry.

https://floridadep.gov/water/mining-mitigation/content/phosp...
Ctrl+Alt+Del doesn't open Task Manager directly, it opens a separate full-screen menu that looks like the login screen with options for shutting down, logging out, or opening Task Manager. It's been this way at least since Windows 7, but probably earlier.
That HIV can and does do that is consistent with what I've read. Some percentage of cells HIV can lay dormant for an indefinint amount of time.
Interesting, didn't know this can differ based on the state. Which ones do/don't let you do this?
The case that was mentioned in the OP is of someone who is renting out only one floor that they bought.

Besides, the main cost in building in NYC is land prices - in the long term the builder isn't worse off by decreased land prices, and neither are renters, while people who want to buy a house are much ahead.
I’m still on board with Uniquiti, tons of equipment and it wouldn’t make sense to switch everything over for small operations. But this is extremely disappointing, they’re definitely moving in a little bit of a different direction then where many of us would hope.

More shiny products that increase bottom line is great but many IT officials rely on UniFi as well, I wonder how they’re responding to enterprise customers.

I just hope this incident will at least get them to put some emphasis on security again as well.
For anybody working with pandoc you should try Weasyprint [0].

[0]: https://weasyprint.org/
Really depends on what the context is. Maybe for a taxi ride when negotiating a price ahead of time, but pointing at an object, asking for its price, getting an estimate that's off, then getting the actual price before the transaction is completed doesn't feel like a scam.
What the hell are you talking about?

Does every Dunning Kruger moron on the planet just talk with authority about science now because they posted the hashtag #believeInScience during Coronavirus?

The numb skulls in this thread need to gooogle retrovirus, integrase, and reverse transcriptase before even typing or better yet even thinking they know anything about biology just because they know how to write a JavaScript component.
Why are you complaining about an article you don't want to read on a site you don't want to read it on? Nobody's forcing you to be here.
Maybe I misread your comment or the parent, but I don't think this has anything to do with what they said.
Distributed Remote Debugging for Python in vs Code
It uses MS Azure Relay, but can help debugging code running anywhere - well, as soon as it can connect to the same Relay.
In many cases they do but neglect to adequately inform employees that may be potentially be affected. At the Google Quad campus in Mountain View there was an incident where some ventilation fans were accidentally turned off which caused employees to be exposed to TCE (affects embryo development so mainly concerning to pregnant employees) that is leeching up from the ground. I'm pretty sure that 99% of the people would not have been able to tell you it was a risk in working there.

Also in the area is the "MEW plume". When I asked realtors about it while looking for real estate in the area they all claimed to know nothing about it - despite being locals and there being land development rules requiring that top soil be carted away to be treated.

So many people/orgs are tacitly working together to ignore the problem since no one wants to be inconvenienced or left holding the bag.
I agree but some problems disappear too. For example, occupants of cars get frustrated when they are stuck for quite some time on a complicated turn that a human would accomplish quickly. Packages don't care either if the driving is not smooth and the vehicle responds in favour and with extra care of other vehicles around it. Not to mention routes that might pick up and deliver multiple simultaneous loads. It just seems that would be an easier first step for the tech that should be profitable. But these are just questions I have. I'm very unsure about what the reality is.
NYT should have done that without glorifying a tyrant for millions of deaths.
What I’m curious about is, if I run my own controller on my own hardware, do I need to be concerned about this? I could understand supply chain concerns... I’ve held off updating anything while this plays out. But all these “breach! breach!” stories fail to spell out who is affected and what they need to do.
I remember tracking down corrupt entries in our DB. It was mostly one user introducing the inconsistencies. Turns out he would double-click on every button, and the browser would happily send-abort-send two requests every time. Sometimes these would race on the server.

We implemented disable-on-submit after that, and the inconsistencies went away. Other people would click again when the response didn't come fast enough, but that was rare to lead to corruption. Probably when their connection was lagging, they would click multiple times in frustration. But that one guy provoked enough destruction to make us notice and fix it for everybody!
It seems that in Figma's case search traffic will be extremely unreliable given that you navigate to the website to use it, while you use a local app for Sketch and others.
Wow! She has the incredible power to hallucinate paper trails into reality, retroactively altering the course of history‽ Amazing.

(Hate to ask, but did you read the article? She was getting medical treatment well before she got air quality readings.)
Quote where I said "the EU is not allowed to create a site".

Also, quote where I said "there's no reason to want to remain in the EU".

The hostility in all of your responses is, um, interesting.
You might get more interest in your screeds if you put the thesis earlier than five paragraphs down. And maybe add a title?
Maybe Vega and its Figures for Papers can help?

https://vega.github.io/vega-lite/tutorials/figures.html
So how would you send a single non-zero byte this way? Or is that why you need the zero byte to delimit your messages? Also it seems that if you wanted to pause your transmission you can’t really “flush” the incomplete COBS frame unless it happens to end with a zero...
You can find him on Signal now https://mobile.twitter.com/Daviey/status/1378645798439768064
Producing custom DNA inside of cells
You can make any module strict by using the XStrict language pragma in Haskell.
Quoting the "Hacker News Guidelines":

"What to Submit

On-Topic: Anything that good hackers would find interesting. That includes more than hacking and startups. If you had to reduce it to a sentence, the answer might be: anything that gratifies one's intellectual curiosity."
Plaintiff lawyers will come into effect if there were actual damages as a result of this. Has anyone heard of actual breaches of their own networks as a result? If not, probably no actual damages
= class action plaintiffs don’t care because no $ for them. Of course this is generalizing but this is usually the calculus. I know this because I am a cyber attorney.
We're still in a very early part of this developing story, and it's hard to predict yet how things will turn out. Here are some of the main points:

- The recent development that might have spurred this sciencemag article is a proposed mechanism for the AZ vaccine to be causing blood clotting in some individuals. This was previously covered a couple of weeks ago. [1]

- The number of people who have suffered serious effects as a result of the AZ vaccine are still much lower than the number of people who could have suffered serious Covid symptoms in the same population. [1]

- However, the demographics don't line up perfectly. The blood clotting seems to be a greater risk for younger individuals, whereas serious Covid symptoms are more of a problem for older individuals, on average.

- It's entirely reasonable for people who are at low risk of Covid symptoms to have concerns at this point about taking the AZ vaccine.

- However, governments are facing the broader issue of stopping the pandemic as quickly as possible and reducing vaccine hesitancy, especially with the vast amounts of misinformation that have been washing through social media. For that reason, while research continues on this potential clotting issue, most governments have resumed AZ vaccinations [2].

- This is arguably not the most intersting AstraZeneca-related thing happening right now. They have also botched several other aspects of their vaccine development and roll-out [3] [4].

- Clotting issues have not been observed in the mRNA vaccines. Those vaccines use a different mechanism to trigger an immune response, and so far all of the indicators for these vaccines have been overwhelmingly positive. Almost one-third of Americans have received at least one dose of a vaccine so far and there are good reasons to be optimistic that the pandemic will soon start coming to an end for some of us.

- Vaccinating the rest of the world is still a large and very important problem. If we don't do that, then vaccine-resistant variants may develop in other countries. From that standpoint, the AZ vaccine, despite its flaws, is still better than no vaccine at all.

[1]: https://www.npr.org/sections/coronavirus-live-updates/2021/0...

[2] https://www.sciencemag.org/news/2021/03/european-countries-r...

[3]: https://twitter.com/zeynep/status/1374349620533411840?lang=e...

[4]: https://www.reuters.com/article/idUSKBN2BR00Q
I'm 100% sure it isn't. Cloudflare docs are not great, and as a Enterprise customer I spend more time with support than needed as a result.
Thanks for the heads up, we're looking into this at Quora.
I see what the author is saying, but I also think the "low code" stuff is catching up. I've seen things people build in O365, Quickbase, Airtable, Knack, and so on that have the same level of functionality I remember seeing in Notes/Domino.
Curbside delivery platform/orchestration for small businesses to manage picking orders for customers and getting them to them when they arrive at brick and mortar parking lot. Could probably be a Shopify app if one like it doesn’t already exist.
There's Programmer Dvorak with dedicated keys for ";", "{", "}", "[" and more.
I believe the term is "computer".

Especially these days, when human computers have basically disappeared as a job.