skysight-inc/HackerNews huggingface dataset:
> "Functional magnetic resonance imaging has transformed medicine."

This is not even close to true. The clinical impact of fMRI is very constrained. I've met many clinicians who have completely written it off at this point. Others that remain interested but find it mostly impractical and error prone. The only people I've met who seem to have any significant investment in it as a technology are cognitive scientists, and that's a ways from medicine.

> It allows non-invasive mapping of a patient’s brain regions to enable more accurate, precise neurosurgery,1"

Approximately nobody does this. fMRI isn't really even on the radar for most neurosurgeons. It's only recently that even detailed structural information (e.g. DTI) has got some real traction, let alone functional info. Note commercial vendors have had clinical packages on the scanners for (nearly? I forget who shipped DWI stuff first) a couple decades now. No such thing exists for fMRI, at minimum you need to buy a 3rd party processing system and may need a research key on your scanner.

Some researchers are interested in this; that's a long way from transforming anything.

> " as well as validating pharmacological effects of potential drugs on human brains.2"

There is perhaps a bit more promise here, but it's still way into the research only end. In the 15 years since the referenced paper was published, not much of this "promise" has been realized as far as I know (but this is further from my wheelhouse)
The fact that the existence of a type of number can be proven despite not finding a single example is very interesting and unintuitive to me as a non-mathematician.
SCO's claims have been shot down by courts time after time in the past. Not sure what Xinuos CEO is expecting to happen here.
Continuing to think about research labs: 14 references (Interconnected)
The funny thing is that the anti-sugar keto people are also even more anti-fiber. They'll tell you that you just need to eat steak and fats and nothing else and fiber is part of the "healthy whole grains" lie. I'm not sure if any of them are into gut microbiome science yet.
Nice morals. In reality, people often take their morals with a side of cash.

Let's turn it around. In Russia, the average salary is around $600 per year. Would you turn down a $50k payout? That's 83 years of an average salary.

Consider that you may be in a privileged position if you can say no to that kind of money.

The solution to this is for vendors to match what the market is paying. If an RCE is worth $50k on Zerodium, perhaps it's worth something similar to Apple not to have headlines about so-and-so exploit being used for cutting up bodies in an embassy.

EDIT: Oops. Divide 83 by 12. But you'll find it hard to locate someone willing to say no to 7 years of salary for ~zero additional work.
I'm mainly a Firefox user on desktop and I don't think I'd use it there, since Firefox already has great support for containers and tab groups (Simple Tab Groups and Multi-Account Containers for me).

However, I will say that from the video demo, your extension looks really slick. It doesn't quite work in Edge (some crashes, collapse/expand doesn't work right), but I set it up in my Chromium install so I don't forget about it.
What is the me= !oxface supposed to read as?
Thunderbird?

https://www.thunderbird.net/
Nuclear weapons would probably be used in case of invasion of either nation's homeland, but lesser non-nuclear conflicts are possible. For example, both India and Pakistan have had nuclear weapons since at least 1998. Neither used them in the Kargil War in 1999 or any of the skirmishes they've had since.
This is most serious option but with russia.
I think I did pass an interview once by pointing out to a compiler guy that an array is just a hash table with the identity hash function. Which I'd read in the Haskell manual the day before.
This isn't a crowded namespace, relative to many other domains. File transfer isn't setting SV and Wall Street on fire. It may look to some like you are capitalizing on Magic Wormhole's reputation, and whether you intend to or not, you may be doing that - people will confuse them.
I can get around 75-80 WPM tap-typing on my iPhone. No weird grip.

Though, to measure that I had to make my own typing test, because after trying multiple websites and native apps, I couldn’t find any tests that didn’t disable autocorrect. Accuracy without autocorrect may be interesting to measure, but in real-world typing, I intentionally sacrifice accuracy for speed and let autocorrect pick up the slack. A test of practical typing speed should take that into account.

If anyone else wants to try, here is my very barebones test:

https://a.qoid.us/typetest.html
> Anyhow, it's insane to me that it took this far into the 21st century for modern medicine to see the obvious when it comes to emphasis of the gut biome in the overall health of the body and mind.

It does make me wonder if anyone in agriculture/food/health/etc has known about this stuff in private, and for how long if so, like how Exxon did private climate-change studies in the 1970s: https://corporate.exxonmobil.com/-/media/Global/Files/climat...
Stocks just want to be traded, Coinbase is just getting ready for when Nasdaq will quote in BTC. ;-)
Nope, you can just use your existing coinbase account to login to it, it's just more "advanced" as in the UI isn't just a buy and sell button, but still very easy to use.
That seems to be the exact problem - why weren't parents setting up play dates?? It's shocking to me how many families seem to think that their kid has no opportunity to talk to another child until schools open again.
* is an inherently more complicated action, and takes 3 cycles on x86 and from 3-5 cycles on ARM. & and - are stupid-simple and take 1 cycle, always. The real question is why this isn't done with ~. Possibly some weird embedded platform doesn't have an instruction for it?

I doubt this string conversion code is ever on the hot path for packet processing, but Click is in general written like everything is.
From Zerodium’s FAQ:

“By signing the agreement, you will accept an exclusive sale of your research to ZERODIUM and transfer all related intellectual property rights to us, meaning that the research becomes the exclusive property of ZERODIUM and you are not allowed to re-sell, share, publish, or report the research to any other person or entity.”
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Email me at kenvanharen@gmail.com
Most of their employees in Myanmar aren't going to be Norwegian.
It's stunning to me that IA.BAK is sort of dead and that there's no immediate efforts to revive it - losing IA in an earthquake would be unimaginable.

I'd love to donate some of my storage, if there was a project to support it.
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Apple now rejecting apps that use data collection SDKs for fingerprinting
No, it's pretty straightforward. If you're on Coinbase, you should switch to Coinbase Pro for the lower fees.
There's a dead reply to this original comment that reads:
"I also liked this article but then remembered the F-35 and have a super hard time thinking we need more investment. Blame the bureaucrats all you want (I'm with you), but I'm no longer sure we even know how make the right things."

I think he makes a fair point. It's not just the bureaucrats. At least in the civilian space, we don't know how to make the right things any more. The ambitiousness of new projects as well as the quality of consumer goods have both been in decline for decades.

In the military space, the deliberate undermining of field serviceability in order to secure more profitable maintenance contracts is a genuine security risk to the entire democratic world.

Given the amount of blatant corruption in the industry (look at the Halliburton contracts in Iraq for a recent example), it is more complex than simply "increase the budget".
The fact that private industry in China serves the interest of the government (and not vice-versa) is a massive advantage they hold over us.
I think a better format would be:

instead of:

p(2 * 3 * 7) #=> 42
^^^^^var

Having:

p(var1:[2*3] * var2: 7) => 42

p(var1) => 6

p(var2) => 7

The other requires ugly whitespacing.
I was programming in Java before generics came out. While generics were a very big upgrade, it was such a disastrous mistake to go for type erasure, because Java has a bifurcated type system. As we all well know, you can't be generic over a primitive type, for exactly this reason. I knew then and have minefield-of-rakes stumbled my way through every single consequence of that decision and still think it was wrong. That decision was made, approximately, because it was a.) too hard to retrofit the existing libraries without erasure and wildcards, and b.) the VM developers staunchly resisted extending class files.

I've been away from Java for 7-8 years, and returning to use lambdas now. At first it feels like a pleasant experience, and it was a neat trick to allow single-method interfaces to basically denote function types. But that early mistake of not allowing generics over primitives hits back again...LongFunction, IntFunction, oi vey. Not adding a syntax for function types, but relying on single-method interfaces seems like a simple, clever hack. But I think it will turn out to be one of those broken-generics class mistakes.

I spent 15 years working on Virgil [http://github.com/titzer/virgil]. Having tuples and real generics is really important to allow a language to be fully combinatorially complete. I wrote a paper about it. Nobody read it. Ah well. Dang it.
This doesn’t jive with reality. My brother lives in an Asian country with very few Covid cases. It’s still not “back” to normal. Plenty of unemployed, plenty of businesses going under, plenty of government assistance for the desperate.
>does "medical bankruptcy" include ... I had no medical bills" bankruptcy?

Well, no. But clearly bankruptcies usually include multiple financial stresses. More likely, "i got sick, i had medical bills, i lost my job, my car broke down" kind of thing.

Worth noting the (up to) 60% figure i noted was from a harvard study during the GFC. The more conservative figures have tended towards 20-30% for medical bills being the primary cause of bankruptcy. Even then it seems to still be one of the more common (avoidable) causes of bankruptcy.
Apparently AD doesn’t scale. Who know. /s
This is a great comment but it assumes the poster has answered their posted question of "Where do you find potential customers?"
You are an island. Our borders are porous. Sure, you can lock down and know that no one is sneaking across your borders. Sab Francisco locks down, and someone drives in from out of town and keeps the spread going.
> Why in the world would you fib about something that is this easy to verify?

Sorry, that was a typo from memory: not 7 and 7 but 4 and 4. Conclusion is unchanged. From the FDA link I provided, Table 19. Here's a screenshot with the relevant line https://twitter.com/breckyunits/status/1348080756921303041/p...

> which you were clearly trying to imply.

I absolutely was not trying to imply these were COVID deaths. I'm trying to imply that the wholistic expected value of the COVID vaccine needs to be considered. In my personal circle of ~2,000 family and friends, I have lost 4 people in the past ~12 months from Non-Covid (35, 50, 65, 62), for a total of about ~100 healthspan years lost, versus 1 person from COVID (with a healthspan left of ~1). I know >100 people confirmed COVID. One cannot make decisions in isolation.

> Now, why were there no deaths from Covid?...that their trial was not designed to surface in the first place.

Because they cut the study short! In the clinical study protocol (https://www.modernatx.com/sites/default/files/mRNA-1273-P301...) they specifically state "To evaluate [Vaccine efficacy] to prevent death caused by COVID-19" as an objective!

"The study is designed to primarily evaluate the clinical efficacy and safety
of mRNA-1273 to prevent COVID-19 for up to 2 years after the second dose of mRNA-1273...Participants are considered to have completed the study if they complete the final visit at Day 759
(Month 25), 24 months following the last dose of IP."

> the foundation for this theory is that the trial participants would have agreed to not get a working vaccination for two years, even if on placebo.

I can't speak to what the experience of people in this trial was like, as I was not a participant, but I have never been involved with a control group where they have told you that they would tell your your placebo status not even halfway into the study.

> I think your suggestions on what Moderna's incentives are absurd.

Moderna the corporation has no incentive to keep the control group going because they've already closed the sale so if the long run efficacy turned out to be not as strong, they potentially could be exposed to downside risk. I am not against the vaccine or the rollout. I'm against the destruction of the control group.
Project Whale Tale: U-2 Flights Off Aircraft Carriers
> Apple became the biggest company in the world not only because they create products everyone wants, but equally because they are masters at managing money and debt.

What, by not having any? The correct amount of cash for a company to have is $0 because it's not a productive asset, as you say, but Apple's strategy ended up with them having hundreds of billions of it overseas. That is literally the opposite of MBA philosophy, not an even better version of it.

(And they own a factory in Ireland.)
I think you've completely misread that comment. When it argues that none of them say 'these are just minor issues', you think it means that politicians haven't even mentioned them. I am pretty sure it is supposed to mean that politicians have been looking at them seriously and not being dismissive.
A recent "real-world" study done in the US between mid-December to mid-March found that people vaccinated with either Pfizer or Moderna's vaccine show 90% protection against SARS-CoV-2 .
Here you can read more about it.
https://www.statnews.com/2021/03/29/real-world-study-by-cdc-...
You mean politicians?
Concepts for future missions to search for technosignatures (SETI)
$600 / month is the average salary per month (according to probably the same Google search you did). Presumably someone reporting security vulnerabilities makes well more than the average.
Late last year, after they restored shadows (I think they'd had to take them out while fixing some stuff, or something) I played most of Morrowind with this. Still intending to go back and finish. Finished the main quest, a huge percentage of the side quests, and Tribunal. Was just getting ready to start Bloodmoon.

What works: everything. Everything I tried. What did I try? All the parts of the game listed above, plus 20-30 plugins, including one obscure library plugin that's not on Nexus. Used Mod Organizer2, IIRC. No problems. Worked great. Know what's amazing? No crashes. Not. A. Single. One. Anyone who played Morrowind back in the day remembers all the crashes. So many, even with stability mods and later versions of the game. This? Rock solid.

What doesn't: plugins that patch or wrap the Morrowind .exe file. That's about it. Oh well.

Bonus round: you can crank up the view distance to fairly high levels on even a medium-good rig, much farther than in the original game. Definitely improves it.
On the contrary I swapped a tough switch for a mikrotik at a remote site (my parents) multiple years ago and it’s rock solid.

Running that stuff on a UPS is super beneficial regardless.
Do Alexa next.... we have so many Alexa devices, and I swear I'm yelling at Alexa more than I am my 3 year old...

My 3 yr old also can follow directions and listen better.

What we need is Apple, Microsoft, Google, Facebook, Amazon maybe to team up and create a voice assistant "platform" that is better, open source, and wide open and could easily be booted on existing smart devices or alexa devices as a replacement.

I just want a smart assistant that works and will behave and do my bidding.
Okay, based on the introduction of the linked paper, this is brilliant. I have seen few if any texts like this one, which treat a fun + interesting + simple idea with fun language while also presenting it in the form of a research article.

Do give this a chance

EDIT: I forgot what day it is. I really like the idea though and I think with a little more work it could really deliver
Beating Super Mario World using the same button input recording for every level
New Zealand raises minimum wage to $20 an hour
Ah yes, because it integrates with your Apple IPad(tm) and your Apple Smart Watch(tm) and Apple TV(tm) and all of your Apple (tm) smart home products, but it's totally not a lifestyle choice.

Sure thing.
SF homes dropped 30% in 2008.

Edit: Actually 44% to be precise.

https://fred.stlouisfed.org/series/SFXRSA
99+%* recover when there's available medical care. There wasn't nearly enough for the entire population if it were allowed to spread unchecked. That's why most countries are going to vaccinate as much as they can until there's enough herd immunity.

* The 0.15% number is absurd when larger percentages of the US and UK population have died from Corona. Even if 100% were infected, IFR would have to be larger.
The abstract is a little concerning, but the good news is that this suggests that the gut biome does have influence on the brain, and perhaps that influence can be reversed or utilized with engineered biomes and/or bacteria.

Perhaps the path to transhumanism will start at the gut.
If you're looking for feedback, you might want to put up a demo template or whatever other bit of the workflow that's easy to expose (at least, temporarily) so you get comments from HN users without the friction of sign-up.
These read no differently than any random startup's slogan.
Yes indeed. In extreme cases, it can give the impression of a xylophone! To control chiff, we use a pointy double-sided knife called a "nicking tool" to create a series of evenly-spaced nicks across the entire width of the flue (which is the slot at the base of the mouth, formed by the lower lip and the languid inside the pipe; air leaving the foot of the pipe is focused by the flue on its way towards the upper lip). Often the nicks are cut into both the lower lip and the languid at similar depths and perpendicular to the flue, although there are exceptions; the width, depth, and spacing of the nicks all have tonal implications. Care must be taken to avoid over-nicking, as the articulation -- some of which is necessary even when chiffing is not desired, and which may need to be more prominent when close to the pipe than when listening from the room -- can be completely lost.
Here's someone doing it with puppeteer: https://blog.fullstacktraining.com/remove-unused-css-javascr...
> it feels like pretty much every stock broker app will now let you buy Bitcoin and they'll do it with lower fees than Coinbase

Coinbase even undercuts themselves. Use the Coinbase App - 2.5% fee. Use the Coinbase Exchange App (Coinbase Pro) - 0.5% Fee.

So... buy your Bitcoin (and others) through the Coinbase Pro website/app, then transfer them into your Coinbase wallet/vault for free.
Do you think the finance department is pushing the changes?
I don't think that this is true. Keto people I've met are very into the idea of 'net carbs': carbs minus fiber.
Just tried it. It appears I am using cross-dos. I've still never had any luck with USB drives though (just tried a USB floppy I have as well).
Need 0RTT like TLS!
I tend to use the stars as a type of bookmarking system - things I don't want to fork, but do want to keep tabs on. It wasn't until later that I discovered their original intent was apparently something different.
Governments have identified commodities essential to economic, military security
What? the iPhone's closed-source operating system?
Where? 30 mins is still in Napa to the North, Oakland to the East and San Mateo to the South.

20%? Maybe in a few pockets. 60%? Never seen it. Even the crummy parts of Daly City the homes are $1M now.
and MMS is still the only thing that works on every phone out of the box...
I hope so, but the way things are going, I doubt I'll be able to get it this year at all.
I agree that changing the definition of seconds would cause all kinds of problems. However, having local time and a local calendar that are synchronized with when the sun comes up and the seasons I think makes a lot of sense, and it won't take centuries to implement. It'll probably happen as soon as people arrive on Mars.

I like Kim Stanley Robinson's approach, as described in the Mars trilogy. They use standard seconds, but at 12:00 midnight, the clocks just stop for about 39 minutes. (Computers just use seconds-since-the-epoch or something and are unaffected.)

Martian colonies will still care about Earth calendars, but only to the extent that they have to deal with Earth. Kind of like dealing with a different timezone on Earth.

https://www.kimstanleyrobinson.info/content/martian-calendar
What are you talking about.

If anything, if you have such disdain for Beats, you should applaud Apple, since they killed the product.

Apple acquihired Beats to build Apple Music with the industry connections, and since then, Dr. Dre left the company to do whatever, and they have completely neglected Beats as a brand for headphones.

Now it's in some weird place where the AirPods are the premium brand and Beats are this weird, budget athleisure brand that they never advertise and will probably kill soon.
Apple needs to know whether or not your phone number is registered with another phone in order to deregister it.

Otherwise people texting your number could have their messages sent via iMessage to the previous owner of your phone number.
>What web-based client will allow you to read email without an Internet connection in Safari?

I understand why it might be a deal breaker for you, but browsing email offline is not a use case everyone has.
This is indeed how it works for the healthcare industry; when I was doing hospital IT, my choices during flu season were either 1) vaccinate, 2) wear a mask, or 3) find a new line of work. I picked the first one.
Take the total storage size on the network, figure out the number of spinning disks, multiply by the power consumption per disk + typical overhead for servers and switches, etc. There’s power consumed by the processing for proofs on data ingest (bigger miners are more efficient at this), but not much afterwards.
Never leave? SF lost 20%+ of its population in the 50-70’s.