skysight-inc/HackerNews huggingface dataset:
From NPR interviews I listened to during the early days of the mRNA vaccines showing incredible promise, I understood that one of the problems with HIV is that the human body does not naturally have strong defense mechanisms (antibodies, etc) for this type of virus. Hence, the usual vaccine path (or mRNA derived method) of accelerating the learning of the body's T-cells, etc. to manufacture its own defenses is not very effective -- they are not there to begin with.

Is that not correct? What are they doing differently here?
Search telegram for fbleaks
I wonder if this is some sort of tax dodge.
Couldnt I just create another NFT of the same image with maybe a slightly different color?
Many who are 'sexually active' are also unwillingly so. By that criteria, it would be best to recommended it to all women and all prisoners in the United States, due to how common rape is among those populations here. I'd like to say "we are better as a society" but that's not true yet, and in the meantime, at least I won't have to worry about AIDS when it's my turn to be raped.
Lucky you! The Commodore 64 to Pentium time frame was only 11 years (1982 -> 1993), and computers were expensive then. Being able to make major upgrades every ~2 years would have been a luxury.
What I basically mean is, I’m really glad I don’t have to spend my time and effort making clothes from scratch or smelting iron, or farming wheat. Or any of the many tasks that led up to making that even possible.

I’m really glad someone else has figured out how to do the many, many extremely time consuming steps (like domesticating sheep and wheat and flax) so that we can now enjoy those benefits.

But I also then feel like, shit, I really ought to be doing something for the world. They literally worked ALL this out for me. I barely have anything I need to do to survive and live an easy life, compared to back then at least.
Sounds like the sale went at least partially to Laina (the girl in the picture)? It sounds like Bad Luck Brian similarly sold his meme.
> I mean, you call it "worst", but I'd call it a blessing, and one we ought to enjoy while it lasts. The moment the powers that be realize that they can capitalize on self-criticism and entirely preempt dissent is the moment escaping said powers will be effectively impossible.

This is already the norm. That’s coming from Brooker’s own experience. The much-less-good episode The Waldo Moment plays with some of the same stuff, and the divisive first episode borrows someone’s quote re: the 9/11 attacks, that the event in that episode was “the first real art of the 21st century” (or something to that effect) because the only thing that’s meaningful as criticism (i.e. not born basically already captive to the system) is so outsider that it’s likely illegal and horrifying... and yet some art-provacateur is trying to bring even that inside the system.
Because it got drowned out by misinformation.
You could, technically, create another NFT of the exact same image. It just won't be the same NFT.
Why would HN be interested in this? Oh wait, it's about making money without doing any actual work.
It's a great pity no cameras were able to capture what must have been quite a sight to behold.
> I keep seeing the requests for central management interface, which leave me somewhat puzzled. Why do you need in a home environment?

Crap wifi was a huge thing I dealt with. Unifi fixed that completely. The ability to run a relatively complex network (by home network standards) with multi access points is nice, but the ability to administer them without CLI interface is great. I loved my edge router but touched it with trepidation. It was rock solid except when I was sucking with it. Unifi suits/suited the enthusiastic amateur.

> I run a small network with one big router and several access points, and at least with Mikrotik's gear, it's pretty much fire and forget.

Unifi used to be too, with an interface that was a bit difficult to navigate (settings spread among about 20 tabs, but it was possible to get the job done without sshing to components).

Now it’s flakey. I just rebuilt my last week which was working fine but I couldn’t log in and the UDM-P screen said it required resetting. Dark times.
If you call requiring tens of thousands of dollars of maintenance medication treatment annually for life a solved problem, then absolutely!
Sorry to hear. Yeah it's crazy out here, for those accomplished and those also still learning the pace of relevance related to appreciation and job entry is chaotic as accelerating factors brings us closer to the singularity. No cultural and structural support for folks is being established really.
Speaking of Vikings, he covered the latest Assassin's Creed too :

https://acoup.blog/2020/11/20/miscellanea-my-thoughts-on-ass...
I attended 3 different elementary schools, all over the place. All the same. They were still looping back teaching the times tables in 7th grade.
Sadly nobody has figured out something like OLE for the web - cut and paste is a hit and miss affair.
No, SkyDrive was always centralized server-side without any of the conflict resolution coauth concepts that Groove had. It was a completely separate project.
One thing that really keeps annoying me about HaveIBeenPwned is the fact that I can enter anyone's email and get their status immediately. This way I can anonymously check if that email had an account at a breached site at the time of the breach. The obvious solution would be sending out a link via email before results can be looked up, but this might not be in HaveIBeenPwned's interest.
The Mach-E starts at $43k.
> I don't know why $47.10 is any less credible than $47

It shows a lack of understanding of either basic science or napkin maths.

For either reality, science or invention, it matters.

https://en.m.wikipedia.org/wiki/Significant_figures
> replacing my USG with my existing home server

I like this idea too, but would prefer that the router was physically separated and before any hardware that was in the network.

Is this a pointless concern?
It's not mentioned which model format the viewer supports. glTF?

UPD: it uses https://github.com/assimp/assimp which supports various formats.
I've used real Emacs in the past. I scripted extensions to it. It turns out that just adding code to microEmacs isn't any harder than scripting.
When people switch from barter to market (currency), does that count as "making more money" and poverty reduction in these stats?

Some getting a job as a cleaner but paying someone else to cook their food, and paying for the commute, isn't a real improvement in quality of life and reduction in poverty. Specialization and economy of scale is great, but at the low end of labor skill, "dollarizing" work at the expense of home economics and barter, is a sham.
I’m done buying ubiquiti equipment. 6 devices, and 3 family members I recommended ubiquiti to who also have multiple devices.

Clearly the market exists for what they’re offering. I am surprised at the serious lack of alternatives.
No, the only two drugs approved for PrEP in the US are Truvada and Descovy, both of which are Gilead drugs.
> The Swazi population faces major health issues: HIV/AIDS and (to a lesser extent) tuberculosis are widespread.It is estimated that 26% of the adult population is HIV-positive. As of 2018, Eswatini has the 12th-lowest life expectancy in the world, at 58 years.

https://en.m.wikipedia.org/wiki/Eswatini

It seems countries like this could benefit massively from an effective vaccine
I don't see it mentioned here, but I wonder if the trees around the apartment are transpiring the vocs that are absorbed from the (potentially) contaminated water. That would be a way these vocs reach her 3rd floor apt, and also may be why her particular apartment is affected more than others.in the building (proximity to a particular tree?)
> The reason why the head can survive without the heart and other important organs is unclear. [...] We suggest that removing internal parasites is a likely function of autotomy, at least in E. atroviridis. All autotomised individuals (and autolysed ones as well) had a parasite, and after regeneration they became parasite-free.

Nature never ceases to amaze.
This still requires treatment for life, though. A vaccine would obviate this need, freeing up time, resources, and money for other healthcare.
For whatever reason, I find it creepy to read about other people having received the same spam that I did.
The Pure Collective | Senior BE Engineer | REMOTE / Redando Beach, CA / Sydney, AU | Full-time | https://puremoto.com

The Pure Collective is a startup that is targeting the intersection between online retail and physical retail (b2b and b2c). We have developed a new approach and quickly built out a tech stack to solve gaps that have formed between brands, stores and customers ever since the inception of the internet fragmented the retail landscape.

Our early builds have attracted significant attention and adoption by a number of major brands and retail chains in the motorcycle industry. Our solution is currently being piloted in the recreational sports industry, but it is applicable and scalable to virtually all forms of retail, across industries, globally.

We are now looking to scale into the next phase and we are looking for an ambitions Senior BE Engineer to join us.

Bootstrapped. MVP in 2020. 550k ARR and growing with B2C eCom revenue stream kicking off next month.
AWS / JAM stack that you’ll help drive the direction on.

https://angel.co/company/the-pure-collective/jobs/1215863-se... for more details on the company and role.

If you are interested in joining a startup with the potential to create a new tech category between online retail and physical retail - and if you have the skills to solve real technical problems in this gap, email me -> jim at puremoto
Perhaps. Do you have concrete examples?
As with everything: "Trust, but verify." https://en.wikipedia.org/wiki/Trust,_but_verify
If there was a cost-effective cure, we could consider it solved. The only (functional) cure for it involves basically taking a sledgehammer to the entire immune system and replacing it with one from a donor with CCR-5 delta 32. As far as anyone's aware, this was only done with 2(?) patients who also had blood cancers.

Everyone else is popping antiviral cocktails and living with both the stigma of the disease and the risk of a relapse if they ever end up not being able to afford the drugs.

So... not quite solved. Hopefully this'll get us closer.
Perhaps it works better in Chrome ? (And that's their intent ?)
Ok I'm over my head with this kinda thing... Someone care to enlighten me on what he did wrong exactly? Reuters expects you to already know the ins and outs of the law apparently
It seems the hackers currently in your network must value those same features. Very convenient.
Having messed with TP-Links smart plugs, I’ve been really impressed. They integrate well into Home Assistant too.
Here's how a packet flows through netfilter[0], and here's how it flows through pf[1].

[0]: https://upload.wikimedia.org/wikipedia/commons/3/37/Netfilte...

[1]: http://mailing.openbsd.misc.narkive.com/jtIB9W3w/pf-packet-f...
You probably don't need to be concerned(ish). I run a controller for 32 "sites" across the UK with 1 to 13 APs per site and a few switches. I keep it behind HAProxy but with fairly minimal changes (from memory.)

I have stuck with controller 5.13.32 rather than moving to 6.x just yet. It's an LTS version and I'm still waiting for the whinging to stop on the forums. I also watch the AP firmware and that has had some interesting times over the last few months. I've confirmed dodgy AP versions on my sites and backrevved and held accordingly.

I treat the whole thing the same way I do any other system. I come out in spots when people mention clouds and IT in the same sentence, so I have not knowingly enabled any cloudy integrations from my controller to UBNT. Specifically, I have not enabled "Remote Access".
Working in the surreal numbers, you can, in fact, add "infinity" (specifically, the one usually called ω) to both sides of an equation, and everything is rigorously defined and works correctly.
> An intel goldmont won’t use much more power and can easily do gigabit sqm and wireguard/IPSec without breaking a sweat. Can any of these nearly 2 decade old MIPS/ARM designs come close? I don’t understand the hype for the hardware either.
Good for her. If people are willing to pay the money then I don’t see a reason why she shouldn’t get her bag.
Furthermore, even on mobile devices, everything just work. Ctrl+f is non invasive, if I close the document in the middle of 100s of pages and reopen the document, I do not need to scroll, unlike many web apps it preserves the scroll location.
It does what it needs to do without any hiccups.
Irrelevant; GP asked for a citation of blue states loving seizing guns.
Can you still take advantage of the hardware accelerated features? Because I use a little er-x and if you turn on qos, that disables the hardware acceleration and top speeds are cut considerably.
It’s not HIBP that caused that data leak. The fact of which emails have accounts on which sites is public following the breach/leak of that site’s data.
One might argue that the vastly increased computing power and big data systems of today have made the Soviet central economy more feasible than ever. Gigantic multinational firms generally operate internally as a planned economy in and of themselves in just such a fashion. This is often cited as a reason for firms to grow in the first place; efficient allocation of capital and resources within the firm.

The trick is to subject that system to democratic control in a sustainable way.
Are you volunteering for the role? It almost reads as if you are expecting to be named on a list of potential suspects.
The decision was unanimous and is really the only possible conclusion from a plain reading of the law. The court didn’t “gut” anything, it’s just a bad law. It’s up to Congress to enact a law that says what they actually want the law to do.
No it isn't. The costly treatment can have heavy side effects... for the people who can afford it, i.e. not most of people who are infected in Africa...
> In particular, how easy will distribution be, considering that HIV is extremely easily preventable but it still spreads, because of lack of distribution of knowledge, I assume.

This is a huge problem in the US. Truvada must be taken everyday to prevent HIV, and in 2015, it cost $1400 for a 30 day supply. In 2021, it costs between $1900 and $2500+ for a 30 day supply in the US.

Elsewhere in the world, Truvada might cost $40. In Australia, Truvada costs $8 for a 30 day supply[1].

The only other drug approved for PrEP in the US is Descovy, which is manufactured by Gilead, too, and costs $2300+ minimum for a 30 day supply.

[1] https://www.independent.co.uk/news/world/americas/us-politic...
Kind of a shitpost:

Anyone read the post title as "HaveLBeenPwned", like Havel from Dark Souls? Who often pwned you the first time around...
The artists used Squirrel hair as brushes.
I’m an amateur builder but the work I’ve done on my house is better than most of the work I’ve seen done by various trades on my friend’s/family’s places.

Quality you get from strangers correlates with how easily the average customer can judge the work (food is easy to judge). Sometimes things are important enough to be regulated (healthcare) otherwise most markets are for lemons.
I didn't know, thank you for sharing!

> If you think the world is overpopulated and has serious environmental problems, you might welcome this news.

It me
Gilead's patent on Truvada (the most common drug used for PrEP) just expired. As of a few months ago it's available as a generic.
I started teaching my daughter letters at the age of three (eg "that letter looks like a snake, what does a snake say?") She was able to read basic signage while going around town before she turned four. She could independently read non-trivial books by the age of five. She was learning the Linux command line by the age of six.

Young children learning to read isn't usually about their own innate ability. It's about whether they have someone who reliably puts in the hours with them. It probably also helps to model the behaviour, so they see you reading books yourself in your spare time.
Crappy writing isn't a style unless it's on purpose, and often not even then. A great example of this is Philip K. Dick, who was a terrible writer by any standard, and not on purpose either, but he still became a great author because the overall effects of his ideas were so good that readers tolerated his crappy writing. The total effect of his ideas were his unique style, not his clunky dialogue or characters with less animation than action figures. He was like the Sex Pistols of science fiction in that he could barely play his instrument, but made the equivalent to some pop hits and he inspired a lot of other much better people to get over their own fears and write.

Authors certainly have a voice, but it's because the whole story is told in it, and not because they interject to comment and give the reader direction using extra descriptions from a perspective that is outside the story. It would be like a director addressing the audience or an "applause" sign. When I read fiction, I read it to appreciate the effect of the author's craft, and not to listen to someone sounding things out and practising. Adverbs aren't forbidden, but I see them as cribs for re-editing because they are usually placeholders for unformed ideas.
I'm pretty sure this was a major theme in Stargate and other scifi series. Slugs shed their host bodies when they're no longer useful and get new ones.
Or he _is_ the culprit trying to get ahead of the story.
Disclaimer: Throwaway account.

There is a way to bypass CF bot protection, which mostly uses basic HTTP features, nothing fancy (and especially not a security issue).
Theory Ninja: Memorize the AWS Icons Game
same reason why education has not prevented covid-19 from spreading.
Can anyone name a kingdom that didn’t exploit?
Everyone uses dark patterns. I remember how I signed up to get info about volunteering for Obama in 2012 and proceeded to get emails about raising money from literally many dozens of different super packs and interest groups. They all used similar patterns and pushed similar urgency...
Drug users are also high risk, as are any medical professionals that work around needles.
A cursory review of your profile suggests you have been having a hard go of things for a while and you genuinely seem to be in a bad spot, and I'm sorry for that.

I know that it is kind of taboo to question mental health here but never the less, I'm going to recommend that you see if you can find a professional to talk to. Someone who is trained and can actually help rather than some random person (like me) on the internet.

Talking with a professional helped my daughter when she was in a dark place and I hope maybe it could help you as well.
Why does this falsehood keep being repeated as the truth?
Very cool that the author had a custom keyboard made with their keymap printed on it.

Personally I like being able to type math symbols on occasion but don't do so often enough to benefit from a custom keyboard layout that I'd then have to memorize. I didn't have a good way to do this until about a year ago, when I learned about Espanso [1] which is a cross-platform text expander. I installed it and set it up to substitute various (vaguely LaTeX-inspired) macros to UTF-8 strings. For example, typing the following keystrokes

x = R cos(:phi) sin(:lambda :minus :lambda:nought)

becomes x = R cos(φ) sin(λ − λ₀)

I chose ':' as a prefix for all my macros but this is just a self-enforced convention; you can configure a substitution for any sequence of keystrokes. Since I gave all the characters names that made sense to me, I don't have to think much when I type them.

A few of the substitutions I get the most mileage out of:

- The Greek alphabet, both upper and lowercase (:theta → θ and :Omega → Ω)

- Double-struck letters for numerical sets; e.g. :RR → ℝ

- :infinity → ∞

- :neq → ≠

- :pm → ±

[1]: https://github.com/federico-terzi/espanso
Why is it about what's "necessary"? There is nothing wrong with wanting to pass on a love of learning, and recognising the ability of a child to participate in the culture of the mind.
Sure, but just as me creating a Mona Lisa-lookalike painting I doubt you'd get a buyer.
To answer your question literally and directly: because a lot of HN users are Americans, and there is a lot of anti-islamic sentiment in the USA in general.

It is widely seen as acceptable in the US.
AFAIK they've started locking them now, since about v5 if memory serves. Got a couple gathering dust now because of this.
As do, I but in some situations it's hard to avoid. But good it works for you.
What hardware are you using?
Flexisheet was created to be a clone of Improv for Gnustep, but it was abandoned long ago. You could compiled the source.

https://flexisheet-orphans.blogspot.com/2006/10/circa-2002-l...

Sourcecode : https://github.com/gnustep/gap/tree/master/user-apps/FlexiSh...

Review of alternatives: https://arstechnica.com/civis/viewtopic.php?f=20&t=546563
I'm seriously starting to think that selling UUIDs of virtual things could really take off. I'd call them "Green Carbon Tokens" because despite their carbon print being negligible, 50% of the profits would be used for carbon capture.

My database would be a text file that anyone could download and verify.

Edit: I mean plain UUIDs, so you could create billions with the same carbon used to create a NFT, and the signed text file counts as distributed because anyone can have a copy, I couldn't tamper with it and not be caught.
From the list, to prove your point at how far this has gone:

> The socialist collective angry bullshit will go on rising from the dead.
> Richard Stallman executed a truly extraordinary feat that has never been accomplished by anyone before.
> Christopher Dimech
> General Administrator - Naiad Informatics - GNU Project (Geocomputation)

You are definitely right, even aside from RMS's personal conduct, the level of personal worship around him is extremely concerning and unhealthy. Its understandable that they want to keep their distance from many of the more corporate-aligned people, but this kind of focus on RMS is just too far. His "St. Ignucius" routine, business card that would not be acceptable in literally any other professional setting, and absurd speaking contract thing all show how this has been enabled for far too long.
Beware Goldman workhorses, deferred gratification is the worst kind
Yes, but you'd actually have to look for or even buy the leaks themselves in order to find out if somebody has been "pwned". I'm not arguing against the service in general, but there's an obvious way to improve privacy.
> Why do you need in a home environment?

To answer this for me personally (and I suspect this is a pretty common answer): To use the best, and to explore technologies that I might suggest to business clients.

Business clients love central management interfaces.

As well, I’m honestly kind of done with managing fiddly “snowflake” devices, and central management interfaces usually come with the ability to standardize the config across devices.
The vaccines that I'm aware of only prevent infection in people without HIV. You can look up the vaccines on clinicaltrials.gov and find out their efficacy in different populations.
Ask HN: What is the best way to configure a Mac/Linux dual-boot
I'd like to set-up my various MacBooks with a dual-boot set-up that minimizes duplication. i.e. if I want to set-up Darling in linux, I'd like to re-use whatever I can from the Mac install vs. redownloading. I'd like to do this for user home, music, downloads, etc. but APFS is a pain and I hear lots of issues. Anyone have the secret sauce or some advice on best practices?
Can Congress use their franking privilege to send texts?

https://en.wikipedia.org/wiki/Franking#Franking_privilege