skysight-inc/HackerNews huggingface dataset:
Yes, clearly. With COVID-19, there is pretty much guaranteed market for about ten billion doses. Along with direct investment by governments in wealthier countries. Most people, including politicians, want a COVID-19 vaccine real bad.

The parent poster was describing the situation with vaccine development in general, to which COVID-19 is quite the exception. A potential hepatitis C vaccine for example has very different economics, as it would not be deployed anywhere nearly as widely or quickly. Consider that, 40 years after hepatitis B immunization became available, the majority of Americans haven't been jabbed with it.
Gqldoc – The easiest way to make documents for GraphQL
I believe this is a way bigger factor than OP comment says: church failing to keep up with modern society.

1000% that's why I am against many (perhaps most by % in the US?) of the organized religious congregations.

those that identify queer, gender-fluid, whatever are told their literal existence is sin. it's hard to imagine how damaging that is if you're not in this community. It'd be like telling someone who has orange hair they are going to hell for something they have absolutely no control over.

In the worst cases they push parents to try to 'change' their kids, which has been shown to be incredibly dangerous and damaging.

Even if you're in a 'liberal' church that says we love gays like we love all humans, but don't think about getting married and in some cases can't have sex, that still does a huge amount of psychological damage and putting us on the outside of 'normal.'
You forgot 99.99999% of what matters when communicating: the context/culture/shared model of the world. You can send a single word and in one context it is a death sentence and in another context it shows that you are part of the group.
If you guys enjoy easter eggs, you might like to know about the easter egg subreddit. https://old.reddit.com/r/eastereggs

Full disclosure: I own/run it. Sorry if there are posts about Easter. Our automod config works pretty well but some posts leak through this time of year ;)
How many doses administered with this particular vaccine? You used your lighting example but it is likely to change of administered doses of AZ are significantly smaller than the 550M.
"keep moving" or something similar is the best advice.. growing to my 50s myself, and watching parents and grandparents, this is by far the biggest variable you can control.

Keep learning, keep moving your body. When you're 15 this is easy, you don't really have a choice. When you're 40+ it starts to become more of a deliberate act.
Does the company have the right to try and convince employees to vote against the union?

It seems to me that they are attacked from every direction no matter what they do or say. I am definitely no fan of Amazon, but the process seems to be a bit one sided in favor of the union.
There are a lot more costs (both paid and environmental) associated with hotels than just laundry? Staff, lighting, heating. Plus eating out, taxis, and air travel.

Also, retirees roaming around the country in an RV generally sit in one place for a week or two at a time.
Check out this video by The Thought Emporium to see how far we’ve come in these matters:

https://youtu.be/J3FcbFqSoQY

This should hopefully provide you with some useful perspective.
They do if they are on the kind of cross country tour that they'd otherwise make in an RV.

Otherwise the argument becomes "Staying at home is better for the environment than traveling", which is true, not not really a fair comparison.
Outsource, buy cheap.
When are the main economic powers going to tax the origin of merchandize based on environment impact, labour rights and such metrics.
Putting a higher customs tax for lower rated countries can be a game changer.
In my twenties, I had an amazing ability to run at a problem. Long periods of great focus. The only trouble was how frequently I was running in the wrong direction.

The gift of aging for me (late 30's) has been the appreciation that an inability to get into flow is usually because I've got buried reservations on a design/approach, and that I need to spend some time trying to surface them.
Thank you. Do Ruckus support wireless downlinks? I can't lay cables here, so the switch in my home office needs to be fed by an access point.
I'm 51 ands my personal experience to date has been that I am way more effective in business now that I have ever previously been. I certainly put in less hours (now only ~40-45/wk as I have a 4.5 year old and various other commitments), but now I have made so many mistakes over the years that I generally focus on what really matters and am finding my impact is substantially greater than it was even though my effort is much lower.
I am trying to build a SAAS service for booking services. One of the engineering issues I ask myself is if the following will become an issue in the future: do I save all the options of slots available I show each customer in the database or do I just calculate the slots virtually and save only the confirmed bookings?
Sounds like something Philip K. Dick would've written. I guess if you squint a bit it's basically a rehash of Minority Report.
They were doing ACH pulls which can be clawed back for 60 days. More than likely they were hit by fraud and the custodian bank was making the decisions to hold the money to mitigate their loss. Beam isn’t holding anyone’s money, there is a bank that sets all all rules and takes all the risk.
Help LBRY Save Crypto: Case Guide and FAQ
> > Unfortunately, Mendel’s work was published in an obscure academic journal and Darwin never saw it

This part is true. Not sure about Darwin's mathematical knowledge.
Semiotic goes WAY beyond simple charting. It has a wide variety of visualization frameworks which serve as bases for highly customizable graphics. I will agree that there are things one can do in d3 alone that are not supported directly by Semiotic, but I would also argue that once one plays with it a bit, Semiotic can produce the vast majority of complicated and highly customized visualizations. And I don't need to worry about DOM battles.
It's not an accusational claim. It's a joke about a popular game. This is not an insane discourse on the nature of evidence, it's simply a reference you weren't familiar with.
Reddit Sets Up Shop in Canada
I think of retirement along the same lines. I plan to remain productive, some of which may be economically oriented, but I simply won't be worrying about the outcome or having someone with power over me telling me how and when I am allowed to do it.
Is this all another medical company needs to start manufacturing and selling the vaccine themselves? Or is this sequence licensed/proprietary in some way?
Anaphylactic shock from an allergic reaction. Here’s the list of ingredients:

COVID-19 Vaccine AstraZeneca contains the excipients histidine, histidine hydrochloride monohydrate, sodium chloride, magnesium chloride hexahydrate, disodium edetate (EDTA), sucrose, ethanol absolute, polysorbate 80 and water for injections.
I really want to learn D3, and I've tried to learn it once before, but I just can't make it click in my head. I can find something and modify it to fit my needs, but I can't get the paradigm of it.

This is such a beautifully and well written article and it's probably as close as I'll get to a digestible tutorial on it, so idk why I'm having such a tough time. I am very proficient at React and have been told multiple times that I'm a top performer at FAANG so idk what's so hard about D3.
You don't believe that we can access meaningful knowledge about the world through logic? If not, then what the heck are you doing on a forum about computers?
Jesus might not have been anti-women, but the New Testament certainly is.

> A woman should learn in quietness and full submission. I do not permit a woman to teach or to assume authority over a man; she must be quiet. For Adam was formed first, then Eve. And Adam was not the one deceived; it was the woman who was deceived and became a sinner.
It depends. The US is behind Western Europe when it comes to reducing superstitious believes (religion). But it will catch up eventually.
With unleashed they do. Its otherwise known as meshing pretty much anywhere else.

https://docs.ruckuswireless.com/unleashed/200.1.9.12/c-MeshO...

If you are talking long distances you need to start looking at directional antennas...But to say..span an A-Frame house...they would do fine as others as well.
right. "typescript runtime" is nonsense.
Currently both Big Sleep and Deep Doze are generating 512x512. These ones are representative: https://postimg.cc/HVspWgPn
Few are "collages", most images have full-area coherence.
as someone who was into building quadcopters in the DIY drones community since somewhere around 2009, I can tell you that the majority of people who had the opportunity to see me flying my quadcopter (in the far-from-society rural wilderness, by the way) during the early days routinely bothered me about the danger of having such a large flying object, and whether or not I knew if anyone like me was placing weapons on-board.

Now you can buy larger quad-copters than I had built off the shelf.

Things change , people get used to it, opinions morph.

When robotic dogs and bipeds become more common place, people will become less threatened by them just due to sheer anxiety fatigue, if not more friendly reasons.

My take : when I see a robotic dog I think "That's a corporation with a spending budget!"
Yea, they are. If for example, you look at the Ford chassis that is the basis for a majority of Class C RVs, the engine tech is a good decade or two behind what Ford is putting in their new trucks and larger SUVs.

Unfortunately the RV industry is one where products are built to be sold, not to be used, and what's under the hood is not a selling point compared to how fancy the interior is.

When reading a review of Ford's new hybrid F-150 a couple months ago, one of the comments at the bottom of the article really stood out to me - "Ford needs to get this in their RV platform ASAP". I tend to agree that that's actually a super clever idea - most RVs already have a standalone generator separate from the drivetrain, and rolling that into a hybrid system makes a lot of sense.
I always assumed that the "God/Heaven in the clouds" meme came from the same source as Greek gods dwelling atop Mt Olympus being obscured by clouds.
Your example really does not help your cause. What’s 150? No idea, gotta look into the docs. The “insane” SVG example is much more readable, its JSX version would actually even maintain types (cx={150} since it’s a number).

I generally agree with the rest of your comment, but that’s just a bad way to show your point.
Ah, I thought about that as well, but I hear conflicting things about what that means for ham radio. I don't have a license yet, but certainly plan to have one.

Someone else suggested Ruckus in another subthread here. If they support wireless downlinks, that may be a good option.

EDIT: If it's known that (quality) power line stuff does not cause interference, it does become a good option.
Yeah sorry, I was counting those under the general label of "ReiserFS".

Reiser5 surprises me though. I didn't expect it to be that uncontroversial. Guess CW topics have skewed my perception.
SEC Charges New Hampshire Issuer of Digital Asset Securities with Reg. Violation
"If you make people call you can charge each person the exact amount that they are willing to pay."

Not really. You're still going to be the first one throwing out the number. -IF- I call (big if), I'm going to say "Here's what I want to do; how much will that cost". If you come back with "Well, what are you looking to pay", my answer will be to hang up.
Why do you assume that "tooling around nature" is the only point of traveling (whether by RV or otherwise)?

I like being out in nature, but I also like having a comfortable bed and a kitchen (with refrigerator) where I can prepare full meals. The cooking part is why I like having an RV - while it's possible to find a hotel with a kitchenette, it's still a pretty limited kitchen (often without an oven) and you have to find a way to schlep your food around from hotel to hotel if you're on an extended trip.

Plus, it's nice to have your own bathroom, especially during a Pandemic.
I have a standing desk and I love to walk and talk so being able to pace unencumbered during interminable zoom meetings has been invaluable to me.

Logitech's wireless is spotty on a lot of products and their G hub application is awful but I love my Logitech headset.
Mexico Covid death toll leaps 60% to reach 321,000
The big money’s going to be in cancer treatments. If they can use this to target tumors, they’ll do quite well.
Oh yes. AT&T asked that their DSL plans were not counted towards their "average bandwidth" because they were "obsolete and no longer being marketed".

To be clear - they were still _available_, and in many cases, your only option, but they were an anchor pulling down the average, so AT&T "just didn't want them to count".
Keyboard has zero value in being wireless. Mouse... that's the tough call because the cable is annoying on a mouse.
I wonder if the elderly man he’s referring to is Buzz Aldrin. The age and description checks out.
"Why bother with a boat when you can just swim?"
Wow, I keep hearing people like Tim Ferris and Dr. Peter Attia talking about using Metformin. I had no idea it is a diabetes medication. From what I keep hearing on random SV related podcasts, it's some anti-aging drug [1].

https://peterattiamd.com/metformin-and-exercise/
There are a lot of services that you don't necessarily need the production level uptime and don't want to pay the high price for.
Australia too. About 30% of the National Broadband Network is Hybrid Fibre/Coax (HFC). 100mbps symmetric is available (for business accounts) and many areas can get 250mbps down / 50mbps up. Some limited areas have even been enabled for (Best Effort) gigabit down.
Cool little game, maybe that will be the next "sim" game to drive big boats down small canals. I did a boat trip down the Illinois river and there is some big barge rafts moving that don't have a lot of room on either side.
Right? I have a set of 4 F710s game controllers hooked to a pi 4 emulation box and I'd been looking everywhere for info on what to do about their flaky connection.
https://www.vesselfinder.com/
This is for any ship longer than 10 m. They need to have AIS. You will probably see why too many ships.

https://www.cruisemapper.com/
This is for passengers, ro-ro, ferry, etc
Altruistic AT&T just wants to let the Freedom Markets™ decide.
JavaScript in Deno doesn't itself run on top of WebAssembly, so this isn't really quite like Graal. If you use Deno to run wasm, all the JS bits are basically ignored. It's a bit like using a web renderer solely for <canvas>.
Thanks for sharing your thoughts.

Could you please share a link to the Twitter talk about "what to do with the list of signatories"?
That's a lot of money to me, despite how much I earn.

Especially when the options are free.
They're both indoors. There isn't natural light in the robot section either. What's the difference? It'd be about the same as being in any big box store other than it sound like like someone roller skating up above.
> entire other half of humanity -- women -- who also weren't in the workforce

What on earth? To think the entirety of women of any age group in 1880 did not work is very "not even wrong" territory. They worked all kinds of jobs, inside and outside the home, from a very young age to old age. Many industries employed more women than men.

Flip to page 208 if you want a table.

https://fraser.stlouisfed.org/files/docs/publications/women/...
Lightning is also a bad comparison because most people try to avoid being outside during thunderstorms but anyway:

> More rarely, anaphylaxis may occur (the UK Medicines and Healthcare products Regulatory Agency (MHRA) has 234 reports out of approximately 11.7 million vaccinations as of 7 March 2021).

It’s rare and in most cases death is preventable with immediate medical attention.

https://en.wikipedia.org/wiki/Oxford%E2%80%93AstraZeneca_COV...

Apparently there’s around 200 anaphylaxis deaths annually in the US:

> There were a total of 2458 anaphylaxis-related deaths in the United States from 1999 to 2010. Medications were the most common cause (58.8%), followed by "unspecified" (19.3%), venom (15.2%), and food (6.7%).

https://pubmed.ncbi.nlm.nih.gov/25280385/
There's also loads of existing industrial robots that do pick and place with suction grippers. It's a pretty well-established solution.
WebAssembly holds a lot of promise for sure, but the interface with the outside world still has to go through JS for now for anything non-trivial. I really do hope that this will change soon.
I'd do about anything on the International Space Station.
What would be the best programming language for this?

R? (pronounced Rrrrrr)

/s
That's a naive view that assumes people are rational but we're not, not even you. Our minds seem to need some amount of hokum (imaginary beings) to remain sane. Children who grow up with a supportive parent who reliably takes care of them carry the feeling of being cared for and the confidence that comes from it for the rest of their lives even after the parent is dead. A dead person is no more real than God, yet they're very influential in helping people cope with life. I think they serve similar purposes. Just think how much people who are not present with you still influence your feelings every day. Until we meet them again, these people effectively don't exist either. It's all in our heads, just like God.

There's even a psychological technique to build confidence by imagining a supportive person helping you. That's even closer to God or Jesus than a real but absent person.
It wouldn't surprise me if that's the eventual end goal. Amazon is looking for good Rust talent too from what I've read.
I dunno. I'd be starting all over again and looking for different options depending on the application. One of the nice things about Ubiquiti was that they did several things well.

For plug-and-play home wifi, Eero might be a good choice, with some reservations.

For slightly larger scale prosumer stuff, I might look for a way to use Ubiquiti's hardware but with something like https://hostifi.com/ , maybe with older-generation hardware that I still trusted.

For the DIY hobbyist, pfsense, openwrt, and kin are still popular.

Honestly, mesh networks have been a tarpit forever. It's been exceedingly difficult to make them reliable, with all the features people want (like access point roaming), without spending a lot of time or money. I got out of that niche a few years back and have no desire to get back in to it.
But in theory you can! Again, I'm not saying that this is the best system, but it does have advantages.
Only if your default search engine is Google and with autocomplete turned on I think.
Many (but not, I think, all—there keep being new announcements) individual makers have extended-release metformin have recalled recent batches and at least temporarily stopped selling it due to detected unacceptable levels of a known carcinogen in the tablets.
ByteDance Valued at $250B in Private Trades
Same. Latest firmware is stable for me, made sure to select a channel that didn't interfere with any wifi networks, and put it on an extension cable. Extremely stable now.
Holy crap! This must be what I'm dealing with.

I have an old laptop that I was trying to fire up to run some lightweight games on. I could not get it to connect to wi-fi for the life of me. Must be the band steering.
I too got tired of the yelling and the fire-and-brimstone-you’re-gonna-burn-in-hell if you’re not God-fearing. That word: “fear”. They were using it as a tool to manipulate.

Finally, I realized, “Why does God want me to be scared all the time?” Shouldn’t God be allaying my fears, not being the source of them?
For example, Gemini lacks language markup so that you can tell the screenreader to pronounce a quoted foreign word(s) in the correct language instead giving it a mangled mispronunciation in the document's default language. In HTML this is done by using span or div tags with lang="XX".
Maintaining one service is still much easier than maintaining individual projects.
If you've got boxes full of lead, there's not much to be done other than redesign everything from the start. But for a box that's moderately heavy - you use more suction cups, increase the vacuum, change the arm path to make the motion smoother, use a coated cardboard to improve the suction cup seal, or other tricks.
Untangling the crossed wires of China’s ‘Super Grid’
For people needing alternatives. I've had good luck with foritgate. Some of their APs are dogs, but the fortios in general has been decent.
Not Moderna, but this [1] was a very useful primer on grokking how the Pfizer vaccine works, especially for computer programmers.

[1] https://berthub.eu/articles/posts/reverse-engineering-source...
AA filed once in 2011, United once in 2002, Delta once in 2005, Southwest hasn't. There may be some coming, but airlines got hit pretty hard with the pandemic.

And there are plenty of airlines that were acquired or folded, but I don't think laying that at the union door makes sense.
Excel finally has a facility for manipulating data that keeps it where you put it. It also incorporates a fairly decent functional programming language. It's called Power Query, not to be confused with all the other things that MS has named starting with "Power" and have no relationship at all and are mostly awful.

The only real annoyance I have with it is that the editor window is modal, like it blocks all the spreadsheets you have open on your machine, and it's primitive even compared to VBA, especially for debugging.

It's not just that it's given me the experience of "this is the way a spreadsheet or BI tool should work" but also "this is the way SQL should work". It's a little cumbersome to do the standard SQL-type operations, but the clean integration of functions means you can implement anything that's missing. Like say, Oracle has grouping sets - you can, and I did, just write a function to do that. I always felt that having a separate procedural language in your database was wrong, but I'd never seen the alternative until now. And I've been falling in love with higher order functions.
Scoop: Substack is raising $65M amid newsletter boom
Maybe a bunch of snowflakes should organize a protest in china
I admit that I have only participated in a minority of all the churches in the US, but I have never attended any church where your statement would be consistent with doctrine on hell, sin, or homosexuality.
Also as part of that "upgrade": we lost the native app and got a Catalyst version that's slower, uses more memory, can't delete multiple threads at once, is devoid of basically all keyboard shortcuts/navigation, and requires 5 infuriating clicks to reply to a message from the notification balloon.
I feel like we're overestimating the value of generating text and selectively picking out things that sound good. This is up for debate, but you'd probably do better to read actual authors and pick things up from them and maybe making your own changes. The time spent parsing the output to see if it's good could be spent on thinking about something to write?

Would be neat to try and publish books with a percentage of AI generated text and see how well they do. Maybe there's a sweet spot for productivity.
Both sequences express the same protein.

Sequences are different because they are differently codon optimized. See https://en.wikipedia.org/wiki/Codon_usage_bias, especially "Effect on transcription or gene expression" section.
“The question is, ” said Alice, “whether you can make words mean so many different things.” “The question is,” said Humpty Dumpty. “which is to be master—that’s all.”