skysight-inc/HackerNews huggingface dataset:
Sequencing technologies have improved immensely over the last decade and a half. And, in this particular case, getting the sample RNA is incredibly easy, since its purity and integrity in the vial is quite high.
So it’s the mRNA version of !important in CSS?
Treat – Themeable, statically extracted CSS‑in‑JS with near‑zero runtime
I'd be keen to find out what I'd find different between using Rmap.io vs Asana's timeline view.

I'm a big fan of viewing gant-chart style for layout and management of projects, though I wonder if it's enough as a stand-alone feature? I get that you have to start somewhere, I guess I'm wondering how you see the end-goal, and if you've chosen the right start-point?
There is nothing special you aren't understanding. NFTs are simply a scam. The Beeple sale was "purchased" by a business partner so the both of them could hype NFTs and profit on selling them.
> I'm afraid Warren and Sanders populism is now unopposed in the Democratic party

Both of these senators ran in the presidential primary and not only were they opposed, they were defeated.
I like it!

Its a million times better than the usual corporate nothing platitudes.
Cool, but it's the lipid delivery system that is the secret sauce. This is equivalent to giving the source code without a compiler to build it.
You are correct. The researchers here sequenced each vaccine starting with the bit of vaccine left in the vial after administration. The goal was to get a raw sequence of the Moderna mRNA component so it can be easily filtered out as being a signal of therapeutic origin. Pfizer's sequence has already been published; it's incldued here to confirm that the result achieved experimentally matches the published sequence.
ect helps about half of patients. that is known from the get go
My thoughts exactly!

Somewhere, Margaret O. Dayhoff is weeping.
Turns out there's an awful lot more to do to 'run your app' than finish writing it and push to github which was the workflow that heroku promised.

I absolutely want to be able to write small personal projects and have them deploy on my cheap server in a sensible way by simply pushing to my git repository.

At the moment I'm using caprover to do this, and it's so much better than doing it myself, but I think there's plenty of space to make this experience better.
*My choices and everything i will do in my life is either Newtonian, and so was decided long before i was born. Or random and so not within my control. -The only issue we have with this statement is the definition of 'my' becomes difficult to pin down.

So of-course, replicate my cells and their states and you replicate 'me', in every sense of the word. In fact since none of the atoms in my body were there 20 years ago i have replicated myself, a few times in my life.

An algorithm with changing perimeters produces different results, a stroke just changes the parameters like any other event, the information in the brain is the result of the algorithm and the iterative basis of the algorithm moving forward in time.. that is what intelligence is, artificial or natural (which itself is semantics).
It really is that “simple.”

Getting it designed and building it is more difficult.

At its core, it’s a piece of mRNA that creates a protein. That code gets transcribed into a protein (often those are relatively short). That protein then triggers your bodies immune response, which trains it to attack covid19.

Inject this mRNA into a cell and it’ll create the protein. Anything can be injected at this point once the mechanism for injection is developed
You assume someone’s identity that’s identity theft...
Here is a glaring example of debating semantics in hopes to discredit the actual meaning of something or attempt to kill the topic altogether. Appears to be a bad outcome from the rise of STEM worship.
Even so, Microvision is better at PR than they are at making products! I suspect this is a dying gasp to bump up their stock price. They barely have any engineers after their last layoff.
Typically the LIDARs that are on autonomous vehicles are pretty low "resolution" compared to smaller LIDAR packages like a Hokuyo or depth sensors like a Kinect. It wouldn't be good for fine detail scanning.
> They did at least pay people, if they surrendered it in time. (Then they raised the price of gold afterwards.)

Wouldn't it be unconstitutional for them to seize and not pay for it? Though they probably just paid face value in paper money.
My source is simply running `cython -a` to see all the highlighted lines, and fixing them and observing how many hoops I have to jump through to get code that doesn't interact with the interpreter.

Cython makes you do more work to avoid the interpreter. C makes you do more work to involve the interpreter.

> There has been a lot of work over the years to make sure of that.

Some cython code can compile close to the C code you'd write.

But that's not how it's likely to be used, because the design pushes you in the opposite direction by default, and the value of Cython is that it's far faster than vanilla Python, and the painless interop.
I know that's not how it works. I'm saying that's not how it should work. Amazon should not be able to abuse its employees by forcing them to go to mandatory "information" sessions under threat of dismissal, precisely because the union doesn't have that power. Either both should have it, or neither should. Which would you prefer?

Edit: I notice you've done this exact same thing in another comment subthread here. Are you deliberately overlooking the fact that I'm proposing a change to "how it works?" That means "that's not how it works, mate" is completely irrelevant.
If you are interested in zero-runtime CSS-in-JS solutions and their pros and cons, read treats background documentation. It is truly amazing; https://seek-oss.github.io/treat/background
Explanation of the state of uBlock Origin (and other blockers) for Safari
Amazon?
Your argument is hilarious.
They are widely known as paying a pittance in taxes.
> think they're focused on the likes of Samsung and Huawei as competition, and lock up the parts to keep them out of the hands of their real competitors

How does that even make sense - the parts are shipping with the devices. And reverse engineering stuff from the device to the point of being able to repair (ie. reverse engineering to the point of a repair manual) should be fairly trivial for invested parties.
Traffic Jam on the Suez Canal
It maybe that I'm in my own personal bubble but it strikes me that so many people still invest a significant time and effort into propagating a delusional interpretation of reality. On some level I bear them no ill will, they are free to lead their lives in whatever way it brings meaning and fulfillment. However many people attending a Christian church seem to have aggressive opinion on how others should live their lives.

The biggest flaw with religion is their story of an afterlife without any proof or evidence. The consequence is that billions of followers of this delusion devalue the importance of their current biological existence, and that of others. They are told they will have an infinite and wondrous existence in a made up paradise. When this shared delusion is the dominant world view it leads to easily excusable murder and abuse of human beings. For example the genocides of indigenous people by European colonizers or slavery.

I suspect our ancestors in a thousands of years will look at this early childhood stage of humanity in shame and contempt for what cruelty this insanity allows.
The Ouster OS0 and Hesai PandarQT are generally much better choices since they...

* match the field of view of the Laser Bear Honeycomb (OS0: 360 x 90 deg; PandarQT: 360 x 104 deg; Waymo: 360 x 95 deg)

* produce 10x as many points per second

* are available for sale to customers who wish to use them in autonomous vehicles

* have no external moving parts that are liable to get gunked up with wet leaves

* have longer range

Although the main drawbacks are that the Ouster OS0 has only single return and the Hesai PandarQT has dual returns, compared to the Laser Bear Honeycomb's several returns.
If you have the time, it would be nice to transfer the data to the commonly used Genbank format.
The line of thought is that ARK will get a chance to purchase IPO shares of say SpaceX for the ARKX fund at a price that your average investor won't have available to them.
Frederick W. Taylor offers some productivity hacks (1911)
Rereading your own posts will reveal how that word persisted at your invitation.
This is because Twitter users, some coordinated on 4chan's /pol/ board, decided to train the bot on extreme racist input:

https://en.wikipedia.org/wiki/Tay_(bot)#Initial_release
Probably out of general ignorance and active campaigns from the manufacturers. Just like no one was concerned about, then were confused about, and then finally started to have very late well-founded concern about cigarettes, and then oil. Plastics are just at the beginning of that curve.
I don't think that's an unpopular opinion since that's a fact, ML is literally statistics. The central question is "given my training set of y, how likely is that my input x is also y," which is probability.
It's not really that simple.

Only two companies in the world succeeded, the French company Sanofi which also tried making a mRNA vaccine failed.
Hmmm...

https://m.imgur.com/a/y73R5Ir
He's also being targeted for his behaviour in the workplace.
I personally can’t wait till iPhone sensors come on a package that can be easily connected to a Pi or a Jetson these will leak into the generic supply chain in 1-2 refreshes.
Got me man, I still have not heard any credible explanation to the reason it got lodged perfectly in there in the first place.
Show HN: Chrome extension to make locally persisted web edits
Ethereum will actually be deflationary in July. The people in that room seem pretty removed from what's going on in the Ethereum ecosystem.
Maybe you just need to avoid management, which frequently requires people to toe a corporate line.
The naming for this product sounds like the marketing dept. just concatenated the most popular options from a word cloud
Here is a breakdown https://berthub.eu/articles/posts/reverse-engineering-source...
discussed previously https://news.ycombinator.com/item?id=25538820
Well, that's the choice of these current websites, which wouldn't also want to support an alternative protocol if one (like the parent post suggests) would get made.

If you need a protocol for document discovery and retrieval like the old internet and have the cooperation of the sites, then you can simply use basic https without javascript, all the things that Lynx browser can support, all the infrastructure is still there. But you can't force the websites to support that if their operators don't share these goals and values.
Why not simply get rid of these taxes?

Sounds counter-productive. Are they seriously hopping manufacturers are going to go setup manufacturing facilities there?

All it does is hurt the local Tech Sector.
Does the union get the same deal?
> P.E.I. is suspending its use of the AstraZeneca-Oxford COVID-19 vaccine for 18- to 29-year-olds.

Not only that, but:

> Quebec, Ontario, Alberta, Saskatchewan, Manitoba, Newfoundland and Labrador and Prince Edward Island have all suspended the use of the vaccine for anyone below the age of 55. Other provinces and territories are expected to follow.

Source: https://www.cbc.ca/news/health/canada-suspends-astrazeneca-v...
Wouldn't it make sense to gather as much funds (from other investors) in order to achieve the most leverage for that scheme?
Unless you can demonstrate how to separate what you classify as "absurd extremes" from your cultural context, I think it's fair to use any examples of stable, religiously upheld, prosperous cultures to criticize traditionalism for the sake of traditionalism.
I think Bezos’ instincts are starting to fail him as he has been elevated into a demigod like status. Let’s see if Jassy brings a bit more sense to PR/Regulatory affairs.
For some reason I always think of an episode from The Wire. Rawls is dressing down McNulty for his latest infraction and orders him to have a report to the deputy tomorrow morning, and the points should have "little dots next to them. The deputy likes dots."

Since then I always separate and mark specific items in a report, usually with bullet points. It turns out pretty often, the deputy does, in fact, like dots. But it's also important to avoid duplication.
You might consider checking out Sunday Assembly[1].

[1] https://sundayassembly.online/about-sunday-assembly/
(Good) comedy writing teams can do “spit-balling” successfully. I think it’s possible. I don’t think “brain-storming” is the right angle to come at the problem.
https://archive.is/VcsEX
I regularly ship 50lb boxes which are 13x13x13 inches to Amazon fulfillment centers. No way they can be picked up and moved by suction on one side.
I like how the MVIS stock spiked to almost 1000 twenty years ago, then cratered to a penny stock until it got pumped recently.
That depends. Are you in favor of coercively using your influence over your employees to get what you want, or would you rather have them have all the information and arguments on both sides?
More like font-weight, since !important is binary and this is more of a gradient.
AP source: VW plans brand-name change to 'Voltswagen' in US
Icos, DeFi, and NFT are just new ways to gamble. Bitcoin competes with gold as the best store of value. Most people aren't interested in gambling, but storing their wealth.
> Is it simply that they took a sample of the vaccine and studied its composition using some standard machine/process?

That’s exactly what they did.
If my little knowledge from biology class serves me correct, RNA uses Udenine instead of Thymine. But in this document it uses T.

Can somebody explain to me why?
I find the idea that AWS will just eat the competition always a little silly as well. I've used AWS managed offerings that were far inferior to the alternatives.
Agreed, this would be ideal. Most people don't understand that literally every access point on a given channel is part of the same broadcast domain even if they're totally separate networks. Every AP that yours can see on the same channel slows down the network for all of them, because wifi is half-duplex. Everyone needs to shut up for a second while one host on the channel transmits.
"minimalist pumpkin" https://postimg.cc/1fvHzzq8
Bummer, I was considering switching to a full Ubiquiti setup in the future. Are there any other worthwhile competitors?
I think you've already fallen for literalness as the only way to interpret or value anything. Which is unfortunate because all of the momentous truths in life (ie, that matter to corporeal beings, to us) are not of the literal variety. You probably know this on some buried level but you cling to the literalness anyway. Why?
You can throw this together pretty quickly using one of the AutoML APIs.
That seems challenging with fast, complex rhythms. I don't know if I'd want to eyeball anything with a lot of syncopation.
If the union pays people $15 to watch pro-labor documentary, I'm sure many people would sign up.
> This is somewhat of a problem for our vaccine - it needs to sneak past our immune system. Over many years of experimentation, it was found that if the U in RNA is replaced by a slightly modified molecule, our immune system loses interest. For real.

> So in the BioNTech/Pfizer vaccine, every U has been replaced by 1-methyl-3’-pseudouridylyl, denoted by Ψ. The really clever bit is that although this replacement Ψ placates (calms) our immune system, it is accepted as a normal U by relevant parts of the cell.

Neat.
not working is illegal.
> In modern no-religion societies, where is the pull for good old family values? What we are seeing is better rights and fairness for individuals (same-sex marriage, etc) but is that good for society as a whole?

I understand where you are coming from, I struggle with my atheism/beliefs too.

But without doubt, this is good for society. Think about it, we had slavery because bible and other religions, approved of slavery. Then women had no rights because of religion, finally they do. These are good things. I believe homosexuality is next big step for humanity. Once this is accepted, no one would even think about questioning it.

As for old old family values, I am not really sure what it means, but if it means close family ties, then I have seen non-religious families who are very close and religious families who fight all the time. And vice versa.
https://www.oreilly.com/library/view/fluent-python/978149194...
(3) is backwards: it's a prediction, not a deduction. I had the theory "LL questions were meant to test C/Pascal knowledge", based on studying `net.jobs`. I then came up with a test for the theory: if it was true, then the C and Pascal newsgroups would spend a lot more time talking about pointers and memory manipulation than other language newsgroups. That turned out to be true. If it turned out to be false, then other programmers are likely spending as much time thinking about memory manipulation as C/Pascal programmers, meaning LL questions wouldn't be a good shibboleth.

That doesn't mean the theory is true, but the fact it withstood my prediction gives me more confidence in it, the same way I'd be more confident in a scientific. Another prediction would be that C/Pascal manuals spend more time on LL algorithms than manuals for other languages. That one I haven't (yet) checked.
> Tell us about yourself.

Cultural DNA is hard to shake.
You're talking about the document, I'm talking about W.'s military history. Even the faked document was in line with all of the facts of that.
From what I understand, companies do tend to automate more if labor costs rise. If your employees cost $30/hr instead of $15/hr, it makes sense to invest in their productivity. This is one reason higher minimum wages aren't the disaster their opponents claim they are. Companies invest in productivity to maintain their profitability. Higher wages do also reduce capital's share of profits, though, which is the intended outcome.
Nothing as ubiquitous though...?
Smithsonian Open Access (3M digital items)
Are Market Makers Like Citadel Bad?
For how I use it, it lives inbetween Spotlight and Numbers. Here's examples of the types of things I can recall using Numi for in the recent past: https://i.imgur.com/u4EdGbr.png

It's list of features is quite extensive: https://github.com/nikolaeu/numi/wiki/Documentation

Plus I don't mind paying for a simple, high-quality tool that I use all the time!
Signs point to yes: https://web.archive.org/web/20190308225112/https://waymo.com...
> When you work for someone else, it is your employer’s prerogative to spend your time how they want. They can pay you for useful productive work or they can fritter it away talking your ear off in the office, within the confines of the agreement.

This is correct. The employer's ability to de facto force someone to sit and listen to a prescribed message, while the union doesn't have the same ability is precisely why either both sides should have that power, or neither.

> Certainly it would be fairer to the union organizers for Amazon to not spend work time on anti-union messages....

Are you against fairness?

> Amazon’s house, Amazon’s choice. The union has to work with the time people are willing to give them outside of the time they sell to Amazon.

Or are you somehow missing or overlooking the fact that I'm literally proposing a change to what the law is?
In retrospect, it’s not clear to me why I somehow expected this project to be something more literally arboreal. I even got my hopes up further when I clicked the link and saw that photo of plumerias.

Yet, this project is cool enough that I’m not even disappointed.
I imagine they do it because they don't want to sell to a competitor.
Does lithium count as a nootropic?

https://pubmed.ncbi.nlm.nih.gov/15581403/

https://www.neuroscience.cam.ac.uk/publications/download.php...
The Pomodoro Technique: How to Make It Work for You
What do you think my argument is?
As far as John Deere goes I think it has to do with the presumed equipment that they could design and send to mars for colonization.

There was a conference SpaceX put on a year or two ago with a bunch of companies traditionally un-releated to space but would be in a good positions to start producing needed goods that SpaceX would want to send on the first 100s of Starships.

Perhaps other companies here fit that list
I have used it. This page of my website has the implementation I use: https://www.locserendipity.com/Pomodoro.html

In my version, I break down the task into discrete steps and give myself a check mark for every sprint completed toward each step.

The simple HTML format makes this more successful for me than the content-rich alternatives available elsewhere online. It also works if you save the HTML file to your desktop—so you can use it offline.
It's worth pointing out that this equivalence is only possible in the English language (and maybe other Germanic languages?) where apparently the word worship means a lot of concepts (adoration, veneration, reverence) that in Romance languages are actually separate. In fact, the disagreement over this words is one of the most important differences between Catholicism and Protestantism.

I don't know how does this distinction work in other religions, but based on Wikipedia[1] it looks like adoration, veneration and reverence may also be different on many of them.

[1] https://en.wikipedia.org/wiki/Veneration
the way I understand it was they govt actually agreed to a pretty healthy pay raise before the strike (inflation was high then and salaries did not go up). PATCO thought they could get more and Reagan went nuclear on them.

this seems like a good write up (dunno the accuracy) https://www.reddit.com/r/AskHistorians/comments/2796do/what_...
I have long thought that math notation is in need of an overhaul, but I mostly just have a general sense of dissatisfaction, not specific proposals or even specific complaints.

Does anyone else feel this way? Do better notations already exist? Or am I just too picky?
Yes, I think that in order to avoid this vicious cycle it's important to establish some good structure in life to avoid said ups and downs.

Limit the amount of work you do, work with clear and simple short-term objectives. Avoid dopamine feeds like refreshing HN or social networks. That hacks your reward pathways and makes you much more prone to BPD if you are already susceptible.

Sleep at very strict schedules. Waking up very early is a great antidepressant, especially if you go out to get some sun first thing in the morning. Besides, exercise in the nature regularly.

Lastly, many gut bacteria are known to produce nasty metabolites that have a direct influence on neural pathways. There's a lot of research lately in Nature & Science about the gut-brain axis. Making sure you have a good supply of short-chain fatty acids and real food is a decent starting point to avoid this.
The ride-share is available at https://waymo.com/waymo-one/

(SpaceX doesn't sell their rocket parts.)
Why ignore the main point of my comment? I directly addressed one reason why a random turtle god and an actual religion are very different.

I was talking about traditions, yes, but to write it off as simply an "appeal to tradition" falls very short
That's not the same deal. Amazon's deal is "here, watch this anti-union propaganda. We won't pay you any more than we usually do, and you're fired if you don't."

Would you be in favor of the union having the same power? Why or why not?
Wait wait, I'm in favor of unions, and I hope they win here, but didn't Europe literally invent the mob?