skysight-inc/HackerNews huggingface dataset:
No. AstraZeneca got involved at the request of the British government. They were not the first choice, GSK was (no 1. vaccine company in the world), but for whatever reason GSK passed, so AstraZeneca, as a British (and Swedish) national champion was chosen, even though they don't have vaccine experience.

There is an excellent investigative report by Le Figaro (in French) that details the many issues the vaccine faced:

https://www.lefigaro.fr/sciences/astrazeneca-le-laboratoire-...

These include friction between AZ and Oxford, the latter insisted on retaining much more control than they would normally have, and this led to serious flaws in the design of experiments for the trials, including not having sufficient numbers of over-65. Furthermore, they mixed samples with different inoculation protocols, raising all sorts of red flags within the scientific community. It does seem the vaccine is effective and safe, but the unforced methodology errors did them no favors, and explain why the FDA and EMA are taking an exceptionally hard look at the data.

Furthermore, production is outsourced to a number of companies with varying level of expertise, and they are poorly supervised by AZ, for instance EU commissioner Thierry Breton performed an inspection in the Belgian subcontractor that has been having problems that led to AZ not meeting its contractual commitments to the EU (and a diplomatic crisis between the EU and UK), and found production and quality control issues the AZ headquarters were unaware of.
Cloudflare Security week: Browser Isolation for teams of all sizes
At least where I am (UK), yes. They added to article 174 of the Human Medicines Regulations, allowing an unlicensed vaccine to be advertised in some circumstances, as well as allowing a broader range of people to administer the vaccine, and provided legal protection in law to the developers of the vaccine in case of any issues.

This is in addition to the existing powers of article 174, which allows an unlicenced medicine to be rolled out in exceptional circumstances.
I actually live in the EU and I don't feel the commission has screwed up on this. I love that we have a somewhat equitable distribution model across the union. The core issues have been with producers heavily overpromising supply on the expectation that approval would take months longer, and with national politicians repeating those unrealistic promises verbatim to their populations to improve their popularity, and then blaming the EU when producers failed to deliver on their promises. AZ has been the worst about this, delivering dramatically less than promised, and have been scumbags in general about it, notifying the commission very late, sometimes after deadlines were already missed. Together with their refusal to be open about export movements EU->UK they've managed to create an enormous amount of suspicion.
You missed the point. Why does Fauci care about the fit of his masks if the vaccine he took is effective?

It's not about what the CDC recommends: if Fauci has faith in the vaccine, why is he personally walking around with two masks on? He should take them off to inspire confidence in the vaccine but... Something must be stopping him. Either there's something he doesn't trust about the vaccine or he thinks there's some other reason he and others should go on wearing masks after being vaccinated. Little people like me must not be privy to that info.

All I know is I don't trust him ;)
I.e. you can solve it by rotating your keys/certificates every 90 days, like the expiry term given by Letsencrypt.
OK, I'll admit that I enjoy Stephen's writing on this topic, though I find it very longwinded. I like that it gets me thinking in weird directions, very outside the box
Living in a safe and homogeneous country. I don't have to worry about being mugged or beaten while talking a walk. I don't have to worry about random episodes of violence. I don't have to worry about protesters burning and looting my home. After 2020 I realized I took this for granted for way too long.
oh yeah after reading the OP i totally wonder why
Oh well, that's it then. I guess I'll only use Backblaze through `rclone` and utilize client-side end-to-end encryption. And I might still not use Backblaze.

A very disappointing article.
> If there's a serious issue with the vaccine and we kept it quiet, the consequences would be catastrophic.

The issue in question is about efficacy, not some unexpected dangerous drug interaction or side effect.

Somewhat lower than expected efficacy wouldn't be "catastrophic".
You could use TextEdit I guess, but I agree that it's not a good experience; it just does slightly too much and not very well.

Ten years ago, this same frustration led me to release Fraise, a fork of Smultron, for quickly editing files.

I now use vim with a terminal to quickly edit a document, as I find most modern editors to be too slow to start (Visual Studio & co.).
Antivirus in Cloudflare Gateway
I believe US intelligence already knows this was lab leak because one of the Biden's intel guys said it was probably "gain of function" research that led to leak. But I think it was accidental not on purpose because the US would retaliate as fiercely as it was retaliation to Japan for Pearl Harbor.

Not the first not the last pandemic that originated in China: https://www.nationalgeographic.com/adventure/article/140123-...

Some time ago I shared here on HN a US research on "The debate on potential pandemic pathogen creation" https://www.youtube.com/watch?v=1OaTwPAQ3v0

Interesting research on bio weaponry.
No, as someone who has experience the internet in the US and other countries, the US does not have the worst internet. Not even close (and I’m talking other western countries).

It’s US-centric because the author doesn’t know this but just assumes it.
That's just 6.56 qubits per factored RSA integer - or alternately, 11.57 days per factored RSA integer. Quite impressive either way!
And how does Norway fit with your narrative?
On the one hand, I kinda agree with you. On the other hand, I cannot think of any other author who solely with the written word has made me physically laugh out loud, page after page, book after book. No other writer comes even close. Maybe he was funny in an obvious way, but he did it with such consistency and volume that it became something special.
Related: Booting from a vinyl record (http://boginjr.com/it/sw/dev/vinyl-boot/)
idk, seems to me weird to go to an interview without preparing for days/weeks for it.
This wasn't the question, but depending on what the issue is, the chances are that I'd give the same advice - "just install Windows". And since you're the author, would you mind to explain what was your reasoning behind why you thought something like this was necessary?
A lot of these are in orbits as low as possible to maximize resolution. Orbital debris is less of a concern there because it tends to de-orbit quickly. In contrast to SSO where debris stick around like with that NOAA satellite just broke up.

https://spacenews.com/decommissioned-noaa-weather-satellite-...
It's about rocketry, but it winds up touching on spy satellites more than i expected: 'This New Ocean', Burrows.
Plan 9 from Bell Labs in Cyberspace
The Russian Sputnik V vaccine is as effective as the Western ones. Fr all its flaws the Soviet Union was a scientific, educational and health giant, and its successor Russian state still is. The Sinopec (Chinese) one is only about 60-70% effective, on the other hand, and unless given away for free, it's hard to understand why any country would want it.

The concerns about Sputnik are geopolitical in nature (weakening the sanctions regime against Russia for its doings in Ukraine, and the persecution of Navalny), not sanitary ones.
> Through proper scoping the "session" can be boiled down to "this single payment request, for X merchant and Y amount", so not a problem in practice?

Why do we need to switch from a system that already meets the requirement to one that needs to be limited via implementation to achieve the same thing?

> 3D-Secure is terrible implementation...3D-Secure also relies on the device you're making the payment on be capable of running a web browser and accepting user input.

I see the problem here - you are conflating protocol with implementation. Nothing about the 3-D Secure protocol requires an iframe, a sketchy webpage, or entering a password (much like nothing about the OAuth protocol requires that the provider uses the same domain they use for day-to-day operations to handle auth requests) - in fact, 3DS2 supports out-of-band authentication.

If a protocol has flaws, that's typically a call to update the protocol (as OAuth itself was updated from 1.0 to 2.0, and as 3-D Secure has been). It's usually not a call to switch to a different protocol that's not actually made for the use case in question and needs to be stretched to fit. Again, the problem of transaction approval is explicitly not one of access delegation (and not every security problem can be framed as one of access delegation).

> OAuth already supports requesting specific scopes and passing arbitrary metadata to the auth server...the bank has no easy & reliable way to enforce per-merchant limits.

Much more information than just the card number is passed along when you make a transaction using a card, including information used for things like risk assessment and rewards programs.

Maybe this is a cultural difference, but it's simply absurd to me that one could think that their bank of all entities has no insight into their card transactions. That there's no trendily designed UI on a system/dataset does not mean it does not exist.
> "DSMB externalisations of concerns are deeply unusual for multinational pharma companies and suggest an extraordinary high level of friction between the DSMB and the sponsor,' Citi analysts said in a note."

It sounds like they're not getting the type of collaboration they want from AZ, so they've raised the stakes.
Yup. This is it exactly. Having spent time in the US and other western countries the US is much better in some aspects and worse in others.
Author here. The generated LLVM IR at the bottom actually make uses of vector instructions, which will make LLVM generate SIMD instructions if supported by the CPU.

For instance, try entering just a long word as the regex, e.g. "helloworld":

%state0.goto.1.0.cmp_mask = icmp eq <10 x i8> %state0.rhs, < i8 104, i8 101, i8 108, i8 108, i8 111, i8 119, i8 111, i8 114, i8 108, i8 100 > ; helloworld
How to heal the 'mass trauma' of Covid-19
The book about him[1] explains how he is a workaholic . Not just by the worked hours, but the intensity of those, context switching between projects and attention to detail, pressure teams, etc...

I understand your point about "waste of his position" and that he could have a more balanced life, but as the books depicts him that's not the case. Nor it was when he was at PayPal or Zip2.

Good (audio) book, btw. I would recommend.

[1] https://www.goodreads.com/book/show/25541028-elon-musk
On a lower-end "business" laptop, every interaction is painfully slow. For example, it takes 2 seconds just to switch to a different chat, you can see the redraw happening in real-time...
Leading Indian E-Marketplace Planning to Launch 25000 Delivery Point in India
Why developers need to stop being “tech fanatics”
New details on military UFO sightings
Why do people rush to differentiate, e.g, the diffs bt correlation and causation, but never question Occam's razor (I'm officially leading the charge to cease its capitalization), which isn't science, isn't a law, but merely a design principle.

It's been treated as an irrefutable endpoint at best and as a spell at worst. I find it a convenient false authority for lazy thinking.

Consider a statement like: "an expressive programming language is necessary to manage a resource distribution system such as a food production, processing, and delivery system." One could quote Occam and say "nah let's hunt and gather," but how is that consistent with our values? Ergo, Occam's quote is a selectively applied false authority. We need to use our heads and put it to bed!
What's Plan9?
The article is not accessible because of the hard paywall. Frustrating as it looks like an interesting read.
but what the motivations of us scientists like Peter Daszak who were single handedly responsible for suppressing lab leak theory.

It wasn't the ccp, it was Peter Daszak and co.
Link to actual explanation from Norton: http://www.pitt.edu/~jdnorton/Goodies/Dome/
U.S. health officials question results from AstraZeneca’s vaccine trial
If you want that to be the standard you can try to uphold it but you'll have little luck. These are political opinions and we just finished the Trump presidency. Political scepticism is frequently uncivil. There is a real and difficult skill to telling someone they might be wrong politely and Stallman does not have it.

Furthermore Stallman isn't mocking them. He is making a claim about why people are acting the way they are and is probably serious in his claim. He's also probably wrong, but being wrong and mocking someone are different things.

The full quote you're referencing is about a long list of things including "prostitution, adultery, necrophilia, bestiality, possession of child pornography, and even incest and pedophilia". Most of that is disgusting, but not anyone's business. I vehemently disagree with the idea that prostitution should be illegal, especially if my money is being wasted prosecuting it. Talk about bailing out a sinking ship trying to stop prostitution. Stallman was also probably wrong on pedophilia - even then depending on what he meant, he didn't flesh that one out very much.

It isn't exactly a damning case against the man when there is one questionable (and vague) addition in an otherwise non-notable list midway down a very long page of random political opinions. Stuff like that being a major line of attack is why he is back on the board of the FSF - the attacks are over trivialities, especially compared to the remarkable success and prescience of his life's work.
Yes, Git P2P. See https://www.ctrl.blog/entry/git-p2p-compared.html and https://radicle.xyz/
I don't think experts are lying to the public, I think they have questions and it's correct they should ask them. But you can do that with a phone call or an email. When you make a press release you're not asking a question you're making a statement. And the statement the media makes and then the statement the public choose to hear are beyond your control. To use the old analogy, there are consequences to yelling fire in a crowded theater.
Ombika, Purely Indian Leading Multi-Vendor E-Marketplace
Because while we have conclusive data that states "the vaccine will keep you out of the hospital", we do not yet have the data that lets us conclusively say "you can't get and spread the virus if you're vaccinated".

Israel's data thus far looks promising (https://www.reuters.com/article/health-coronavirus-israel-va...), but they're being careful because they don't yet know for certain.

Again, "I don't know the answer" isn't the same as "there is no answer".
None of those follow WHO's best practices for naming new human infectious diseases, published in 2015.

https://www.who.int/news/item/08-05-2015-who-issues-best-pra...

“In recent years, several new human infectious diseases have emerged. The use of names such as ‘swine flu’ and ‘Middle East Respiratory Syndrome’ has had unintended negative impacts by stigmatizing certain communities or economic sectors,” says Dr Keiji Fukuda, Assistant Director-General for Health Security, WHO. “This may seem like a trivial issue to some, but disease names really do matter to the people who are directly affected. We’ve seen certain disease names provoke a backlash against members of particular religious or ethnic communities, create unjustified barriers to travel, commerce and trade, and trigger needless slaughtering of food animals. This can have serious consequences for peoples’ lives and livelihoods.”

Diseases are often given common names by people outside of the scientific community. Once disease names are established in common usage through the Internet and social media, they are difficult to change, even if an inappropriate name is being used. Therefore, it is important that whoever first reports on a newly identified human disease uses an appropriate name that is scientifically sound and socially acceptable.

The best practices state that a disease name should consist of generic descriptive terms, based on the symptoms that the disease causes (e.g. respiratory disease, neurologic syndrome, watery diarrhoea) and more specific descriptive terms when robust information is available on how the disease manifests, who it affects, its severity or seasonality (e.g. progressive, juvenile, severe, winter). If the pathogen that causes the disease is known, it should be part of the disease name (e.g. coronavirus, influenza virus, salmonella).

Terms that should be avoided in disease names include geographic locations (e.g. Middle East Respiratory Syndrome, Spanish Flu, Rift Valley fever), people’s names (e.g. Creutzfeldt-Jakob disease, Chagas disease), species of animal or food (e.g. swine flu, bird flu, monkey pox), cultural, population, industry or occupational references (e.g. legionnaires), and terms that incite undue fear (e.g. unknown, fatal, epidemic).

WHO developed the best practices for naming new human infectious diseases in close collaboration with the World Organisation for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO), and in consultation with experts leading the International Classification of Diseases (ICD).
Quoted from you, just now?
Good explanation, but it doesn't make things better. :(
AZ admits they shared old data: https://news.yahoo.com/astrazeneca-share-latest-data-panel-1...
What is the source of that quote?
Discord is a privately own and funded company. It is not public ally traded. What am I missing?
I listen to the Arms Control Wonk Podcast and they often go into open source analysis of North Korean or Saudi or whoever's current projects based on finding test sites with pictures from this sort of commercial satellite imagery. Recommend if you think that sounds interesting.

https://www.armscontrolwonk.com/
Also probably you should think about all the other security low-hanging fruit first.
A lot of these sites will even change the letters they ask for every time you reload the page. So the number of observations is probably less than 10. Maybe 1 if you have access to decent chunk of IPs (assuming they will block you if you reload the page too many times).
I met Douglas Adams once at a public appearance. It was one of the great honors of my life to tell him, personally, how much his books had meant to me.

He was friendly and gracious despite seeming, to me, rather uncomfortable with the throngs of people there to see him.

In addition to feeling slightly bad about being part of said throng, I always remembered and admired that about him.

It's easy to be friendly and gracious when you're comfortable; it's quite another to manage that feat when in truth you'd rather be anyplace else.

I often think of him. I'm so sorry that we lost him so soon.
Try using 'Stickies'??
From that article:

> The findings of these simulations should neither be generalized to the effectiveness of all medical procedure masks or cloths masks nor interpreted as being representative of the effectiveness of these masks when worn in real-world settings.

I think complaints are justified when CDC officials turn around and do exactly what their report says not to do: interpret the findings as being representative of real-world settings. A year in and with trillions spent, our evidentiary standard should be higher.
most of the crazy email regexes found here https://stackoverflow.com/questions/201323/how-to-validate-a... fail to validate in the input field
> We need to avoid demonizing China over this if we want to ever find out the truth and learn how to prevent another pandemic outbreak.

I think it was western scientists like Peter Daszak who suppressed lab leak theory in fear that their research will be demonized forever.

It wasn't CCP who called everyone consipiracy theorists it was Peter Daszak and co [1]. I don't understand how he can be the WHO investigator of his own lab [2].

1. https://www.medscape.com/viewarticle/947620

2. https://www.taiwannews.com.tw/en/news/4119101
> there should be preferably ten thousand subtle different ways of doing things

This doesn’t sound elegant (meaning “pleasingly ingenious and simple”) at all.

It also only seems readable in the most shallow sense - certainly not understandable.
It's an interesting theory but like most items in quantum computing it is purely theoretical. Not sure how much it would cost to build.

I hope someone gets a grant to work out the engineering difficulties in this.
Ah thanks -- I was wondering why they wouldn't mention it if it was ZFS, would have made a good addition to the article. I guess they didn't say because it was something proprietary?
I used to use Keepass with auto-type. I had a hotkey for it, and it would recognize the site based on the browser window title.

That would probably be the best of both, no clipboard, and no browser addons.
Microsoft's Xbox Network is a reaction to the free-to-play boom
Golang itself is condescending. It was basically invented as a way to get fresh CS grads productive ASAP with as little understanding as possible.
All modern browsers now ship with a password manager (Firefox is currently rolling out CC filling country-by-country) so that number can't be too low.
Seconding this, it's a great hobby. The act of creating a handwritten letter can help you to think about what you really want to express with your message. I recently used sealed letters to write to some old friends of mine, and the folding pattern I used was taken from "MIT's Founder William Barton Rogers letter to his father" (also on this channel).

In combination with forums like fountainpennetwork this YouTube channel can help you reconnect with old friends by sending letters, which - like postcards - are even more fun if they are unexpected.

The next step for me is to use subreddits like penpals or fountainpenpals to find strangers to exchange letters with, which should get rid of the embarrassment about my rather bad handwriting.
I think this is the problem that 'original sin' fixed. It seems that everyone believes they themselves are good. And thus, they know what's good. But, I doubt that any of us are good. And I don't think good objectively exists, in any case.
Could you explain why it's BS? (Asking for a friend not in ITSec.) Thanks!
Conspiracy theorist. Trust the science! /s
This reminds me to listen to MC Frontalot's Secrets from the Future again. If you haven't heard it yet, you're in for a treat! https://youtu.be/FUPstXCqyus
Animated Social Media Icons Using HTML and CSS
Check out https://snapdrop.net for a similar product with drag and drop capabilities (no password though)
> doing no harm to other people

This is not true. It gives children a false impression of what sex is like in reality. I don't need a scientific paper to tell me that children looking at this stuff is bad.

The rise in the number of incelibates around the world is dangerous and it must be due to the wide availability of pron. Just take a look at what's happening in Japan.

Parents who don't want their children viewing this kind of thing can't block all the 18+ discord servers. (Although I personally don't think kids should be using Discord given the amount of grooming that goes on).
You expressed concern about anti-vaxxers, correct? If it turns out the AZ vaccine doesn't work very well, that's a boost to them, especially if the conversation occurred in private. Perhaps that will result in more people dying in the long run due to decreased trust in institutions.

When you play this utilitarian game, you can kick the consequences can down the road forever, which is why it's better to think of these arguments in more immediate terms.