skysight-inc/HackerNews huggingface dataset:
>"The Berlin Patient," as Brown is known, received stem cells from a donor who was immune to HIV. In fact, about one percent of Caucasians are immune to HIV. Some say it goes back to the Great Plague; People who survived the plague developed an immunity, and that immunity was passed down to their heirs today.

Immune to HIV. That's news to me, so i decided to do a bit of research.

The gene responsible for this immunity is CCR5-Δ32. It blocks a receptor in white blood cells; not allowing the virus to attach. The original patent for finding this gene is awarded to a Aaron Diamond AIDS Research Center in New York.

The HIV virus first binds with the CCR4 protein, and later CCR5. A mutation in the CCR5 prevents the virus from infecting T-Cells and is what causes this immunity.

"A person obtaining two mutated CCR5 genes will be immune to the HIV virus. However, someone containing one mutated CCR5 gene will be resistant to HIV but not necessarily immune. If a person with one mutated CCR5 gene becomes infected the infection tends to have a more lethargic course of infection, than someone without a mutated CCR5 gene."[1]

The gene is found in a lot of Swedes, but decreases as one moves deeper into Northern Europe. Approximately 10% of Europeans have the mutated CCR5-Δ32 gene. I found that especially interesting, seeing as the patient in this article received the marrow transplant in Germany; as opposed to the US or otherwise.

I think HIV/AIDS is a very interesting virus. The new small pox of sorts.

[1] https://sharepoint.cisat.jmu.edu/isat/klevicca/Web/Case_Stud...
Too much media, stress, struggling. Severe stress is the cause (one of multiple) of most mental disorders. Genetic predisposition needs to be 'activated' - so stress is the 'activator'.
I think it is also co-related with Flinn effect - the media (newspapers, advertisements, radio, phones, TV) 'trains' the brain as people do train muscles in a gym.
> He's trolling for pageviews/loyalists and I hate that

Meanwhile you're trolling for karma and you love that?

> I keep reading his articles expecting [...] objectivity

Oh come on, you're not writing that seriously now are you?

> Really? Not plugging your phone into USB and then fucking about with iTunes is "dare I say game-changing". What decade are we in? Oh wait, maybe this quote was missing some critical bit of context... If so, fill me in. If not, FTFA.

It's game changing not because it's novel, Gruber is in fact well aware that Android or WebOS have had OTA sync of everything for a long time (he's mentioned it several times in the past), but because it plugs one of the biggest holes in the iOS platforms, especially w.r.t. the iPad: the systematic reliance on computer tethering for almost all operations. That is a major iOS drawback right now, and a major advantage of competing platform. If Apple can plug this hole, the value proposition of iOS (again, especially on iPad which feels much like a computer and on which the over-reliance on computer tethering really is uncomfortable) skyrockets.

> Oh wait. Netflix. (To which someone says, "but they don't have everything"; to which I say, "they will".)

Netflix does not let you buy movies. That seems to be what Gruber has issue with here: if they pull a movie from their catalog, it's gone. The point of buy would be to stay in control of the media: if the studio decides to pull the movie from the catalog, you still have it. If you want to download it to whatever device for offline viewing, you still have it.

> If I wait longer, will this sentence become not-dumb?

I don't know, do you think waiting will teach you the fine arts of understanding written words?
Build a free version of your app. I suspect some of the pirates want to try your app for free.
And I've personally observed these Jehovah's Witnesses in the grounds of detention barracks. Let me ask you then: what would you do to apply the conscription law equally? There is no "escape clause" even for sons of state officials. All males have to go through it and the citizenry have come to see it as a rite of passage.
While it's entertaining to think of wannabe terrorists reading materials about cupcakes, surely this is a missed opportunity?

Wouldn't it have made sense to plant almost-correct recipes for bomb making, back-doored advice on computer security, and lukewarm calls to Jihad?

(Maybe this has happened elsewhere - and this is just MI-6 thumbing their noses at the website owners)
any speculation on when the head crabs are coming?
This is a silly argument and a misinterpretation of the purpose of orthogonality. Orthogonality is not a goal in itself, nor is it's purpose to eliminate redundancy. It's a tool to reduce entanglement of features. It helps simplify designs by ensuring that changes to one feature do not affect other features. This reduces the chance of unintended or inconvenient side effects when making changes. This is helpful for software architecture in general, not just programming language design.
Judging from the other comments here this may be a surprisingly unpopular opinion, but if you're pirating an app that costs one fucking dollar you should be ashamed of yourself.
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Would be clever if they could fight off the PS4 using this sort of angle. Too bad that the video hardware industry would collapse to just AMD though.
Perhaps the Chinese government would like to explain why 99.9% of SSH attacks on my server (which has password auth disabled) come from China.
This is the perfect way to hide such actions, though - an extremely obvious change, so that more subtle changes will be ignored. The article does note that MI6 is continuing to target the magazine, too, so it wouldn't be surprising if they were making subtle changes.
An act of war would probably be anything done by a foreign nation intended to cause loss of life or a great deal of damage to physical property. Going ga-ga over the "cyber" part is as stupid as it is distracting. If warships sailed into NY harbor and opened up, no one would go "gah! a boat attack!"
Remember the 911 logs released by Wikileaks and all the AIDS medication alerts; time to take your medicine? Hope one day there is a cure, but until then, I am glad we live in a society that fights to see these thing gone.
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fyi, autocorrect has made its way into lion..ios style. It's fucking miserable.
If it's just a perception of the west why not tell the Chinese people about Tienanmen square? Perhaps then the Chinese people would have similar 'perceptions'
Requiring users to create passwords continues to be an engineering failure in our industry. There are some promising alternatives, but we need to realize that users are not at fault for picking poor passwords. We are at fault for not giving them better options.
Its a nice way of messing around with people's minds. Makes AQ sound like amateurs... kind of like Sony. (couldn't resist)
That list on Quoratop is dominated by tech bloggers and pundits. Not industry experts. Just a bunch of people with tons of followers and hours logged on Twitter and at conferences. When you can converse with core contributors to openbsd, openssh, and ffmpeg, the guy who wrote fucking bsdiff, and the creator of the first worm, that's really impressive.

As a sidenote, this is probably one of the biggest things I miss about HN's old days is how great the discussions were with such legends. The creator of Gmail & Adsense talking with you was a daily, awe-inspiring thing. Not that it doesn't happen still, but a lot of this old guard of commenters comment less and less with new vocal pipsqueaks filling up threads. Not that they don't bring value, but the old guard had a way with words that conveyed thoughts concisely.

But I think your argument stands, there are a lot of different and varied industries and interests represented on Quora. The only problem is that a lot of the questions and answers seem a little fake and dry. Everyone's got their name and reputations on the line, so there isn't much outside the usual rhetoric and repeated arguments. Though I will note once in awhile a gem appears from the trough.

The best sources for serious discussions online seem to have moved from Usenet newsgroups over to the pantheon of topic- or expertise- specific forums; Nuclear Phynance and Wilmott for quants and finance+banking, HN and a few other good forums for tech, CollegeConfidential for education, BodyBuilding for fitness and health, etc. And the huge constellation of niche, smaller forums. Then there are the generalist forums like Something Awful and lots of smaller ones with vague or whimsical/unrelated beginnings or purposes. IRC is still a great medium as well, but heavily tech-focused.

I think Reddit fills a hole here in a lot of areas, especially in the smaller and more focused subreddits.
Well it's almost a stereotypical issue, but from where I see it, I can sort of agree to what you pointed out, about the legal issues and what not, but considering the fact that not all teenagers are party-fanatics, drink alcohol.

Their is a good chunk of teens out there that put their mind and thoughts into what they like best, such as their hobbies. Some have dreams of being in the NFL, some dream to be doctors, etc.

My point here is that a lot of people in our society think that teens are worthless, they have to look outside of the box. In particular, entrepreneurs, and investors need to look out of the box, they have to see their background knowledge, what interests they have, almost like any other entrepreneur they invest in.
Really? Now that they know that they are compromised, they will actively look for all changes.
Nah, it’s not. You can actually use the keyboard to dismiss suggestions.
If it's a PDF there would be much more insidious things to do like embed an a tracking pixel. This really doesn't sound like spooks.

I wonder if they inserted any CPA offers into the cupcakes article. This whole lone wolf thing sounds like the perfect demographic for some online dating offers.
Don't over complicate things
10.6.8 is an update that prepares the app store to distribute OS updates. It makes a partition on your primary hard drive that you boot from to upgrade.
I agree with you also, but in terms of age, it doesn't have to matter.

Running a business can mean anything, but running a start-up backed by an investor, and valuated at $10M+ isn't heard of from entrepreneurs 19 and below.

I want society to think of the teenagers that have interests in what they like to do, can do it, but I don't want to have the feeling that people will watch the teenager and have an eye on them more than anyone older than 25. I hope you understand, what I'm trying to say here.
That is much less preferable though.
Somehow, I have the feeling that you're wrong.
The short answer: because tax, though important, isn't everything.

Most startups do not want to make immediate shareholders of new people as the company is growing. They want to test them first. Hence, the standard grant of options with one-year cliff.

Another important reason not to use restricted stock as the norm: you have to pay for the stock up front and (once you get beyond the founder pricing which normally is not offered to other early-stage people) this creates financial risks for employees who would rather not commit cash to the company until they see how it plays out (with options, you need pay only when you decide to exercise). tptacek makes this point well elsewhere in this thread.

This practice of limiting restricted grants to the founder group only is not legally required but is widely done as a prudential matter. I think it is a strongly held belief among founders and investors that it is unwise to be too loose in making people shareholders. Thus, getting a restricted-stock grant has, by custom and habit, become a sort of "founder's privilege."

We have had companies that use restricted stock freely beyond the founder group. In the right cases, this works fine and sometimes there are even special reasons why it is critical to use this approach (e.g., after a small equity round, to avoid 409A tax problems where the company wants to make grants at an aggressively low price but doesn't want to pay for an outside, independent appraisal to keep the grants within the 409A safe-harbor provisions - in such a case, using options can be dangerous while using restricted stock can avoid the tax problems).
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Voltaire wrote, "I have never made but one prayer to God, a very short one: Oh Lord, make my enemies ridiculous. And God granted it."

It looks like MI6 have the same idea, to make Al Qaeda look like a bunch of chumps in public. This is some quality propaganda, precisely because of how silly it is.
I'm actually writing my diploma thesis using Markdown and Pandoc. Some hacking is necessary (sed is so far sufficient), but it's a lot more pleasant then writing LaTeX directly.
"But the really startling bit is the use of non-alphanumeric or characters: Yep, less than 1% of passwords contained a non-alphanumeric character."

This doesn't surprise me at all. Non-alphanumeric characters are hostile for users to type in often. Add other peripherals like phones and a PS3 controller and it's even harder.
Back in the day, writing a program that could read in and print a list of numbers from a file, sum them, and potentially even add and remove numbers from the list, was an achievement and amounted to something half-useful. Today, you can do the same thing in a couple of seconds with a spreadsheet. To do something useful with a modern machine, the program needs to be more complex. Having simple incapable machines again wouldn't be enough; they would be too frustrating to use.
That "new payment system" is quite possibly interfacing with, say, mainframe code written in the 70s. That's often the source of banks' ridiculous account restrictions.
I think in the grand scheme of things his success has been modest. Given this he should refrain from such cut-and-dried statements of fact. IMHO his opinion is valuable, but (by definition) restricted to his own experiences and doesn't constitute the be all and end all.
What would you suggest as better options and what are some examples of the ones you've alluded to? The way I see it, any shift away from the current common scheme would cause problems with either of both compatability and ease of use. It'd be awesome if everyone had a pgp key or something, but that's unrealistic. Some new voodoo scheme gets concocted and I worry for security rigor and whether it'll fit within existing systems.

Maybe the two-step auth method by Google (and by banks before) recently or a tweak of it is the way to go?
This makes it sound like shares are far too risky from a tax standpoint to be worth it for anyone but founders. Startups are risky enough from a career standpoint without having the threat of personal bankruptcy hanging over employees' heads. Is this generally the case or is there a way out?
Did you extend Pandoc or Gitit? I would be very interested in extending/changing Pandoc slightly, but so far I got along with doing my changes with sed and writing some inline LaTeX.

If you extended Pandoc, do you mind giving a pointer to your source? I write Haskell poorly, so an example would be appreciated.
Even more striking: “When administered as antidepressants, drugs that increase, decrease or have no effect on serotonin all relieve depression to about the same degree.”

Any drug that has palpable side-effects works about as well as current antidepressants. The most astonishing example is tianeptine, a Selective Serotonin Reuptake Enhancer. An antidepressant that has a main mechanism of action that is the exact opposite of SSRIs, but is just as effective. However you slice it, that's utterly fascinating.

Either tianeptine has a yet-unknown mechanism of action, in which case there's the potential for a whole new class of drugs, or it doesn't, in which case the serotonin hypothesis has to be fundamentally rethought. If there was any amount of intellectual honesty in psychopharmacology, there would be a huge research effort to decode exactly why tianeptine works. As it is, nobody is prepared to even fund FDA approval. A cynical man might wonder whether more attention might be paid to the drug if it were still under patent.

IMO this is the smoking gun of modern psychiatry. Nobody wants to talk about tianeptine; Nobody wants to talk about why nobody wants to talk about tianeptine. I cannot imagine any possible explanation that isn't absolutely damning.
Half the city? That much antimatter would take out half a state.

1Kg of antimatter is about the energy of the Tsar Bomba if you want to try it out: http://www.carloslabs.com/node/16
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We are way before even "invent a candle". Creating a candle was at least possible, making antimatter in quantity is currently not.
I guess you've never read the Open Letter to Hobbyists.
http://en.wikipedia.org/wiki/Open_Letter_to_Hobbyists

The best thing to do is estimate the number of users and use it in the marketing. (eg. instead of 200 copies sold, say 2000 users, etc)
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I would say, "bad program design breaks modularity", not early typechecking. If your types are defined so that they are as broad as possible (i.e., "what you really want"), then you will never even notice there is a type system, until you try something impossible.
Widen your scope beyond just the US.
Agile should not marginalize software testers?
The Go distribution already contains plenty of idiomatic, well written and very readable code.
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Intents are an open messaging system. The fact that they use java package names shows you they're meant to be user-extensible and infinite.

Compare this to the bit-packing retardedness that is the Win32 message crackers[1]. Commercial software companies used it just like intents, and whenever you licensed "components" you got a print-out of all the magic constants the developers thought were available.

Dammit, Java IS a better language than either C and C++ for application development.

--

[1] Remember Me? MagicProc(HWND hwnd,WORD msg,WPARAM wParam, LPARAM lParam);
We did, and they didn't want it. SSL client certs, maybe. There's Login with twitter, Login with Facebook. Login with Random Site X. Oh, don't like centralized third-party authentication? The only thing you know about security is that there needs to be a lock icon? Try something else, here's OpenID: distributed, federated, customizable. Oh, too hard to understand? Confused because the address bar changes? Why are you asserting your identity on site X when you want to access to site Y? Don't even know, or want to take the time to, understand what "asserting your identity" means? Well then we'll just let you log in with a username and password.

Oh, did you forget your username? Is your caps lock key on?

Even (edit: fake) celebrities known for crazy beards and drunken movies have an opinion on login security: http://twitter.com/GALIFlANAKIS/status/77372216957861888
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Most of the chinese people I have spoken with know most of the facts around Tienanmen square. It is the constant pro-communist propaganda that shapes their views. Just as constant pro-west propaganda shapes ours.
I think we should keep in mind that the damage done to Google's business interests as a result of this conflict is massive. That's why I tend to think that the data they see leaves little room for other interpretations.
Indeed, this seems fairly common... http://news.ycombinator.com/item?id=2564487
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Hostile? Really? How is typing '$' instead of '4' any different from typing 'A' instead of 'a'? They both use the same shift key. Watch, I'll do it again. How about a seven? See? 7.

Now for the ampersand...just hold the 7 and reach for the shift key... &%$#$ FUCK! The little bastard just BIT ME!

I'm sorry, you're absolutely correct - those non-alphanumerics ARE hostile.
Q1, you're assuming you can design upfront; that is, that you understand the problem, you have enough information to solve the problem, the world won't change and so on.

Q2, the ceremony of types itself has a cost. You have to think about it, type it - and you may need to change it. When types ripple through layers of calls, the changes do too.

Note: I don't know the answer. I notice that dynamic languages seem to be becoming more popular (are they? or are they just more publicized?) In a rapidly changing world, it's more important to adapt now than perfect. There's a general trend, that because computers get faster but humans don't, more and more of the work will be transfered to the computer. Dynamic languages do this in the sense that they are less efficient than static languages - on the assumption that speed is the main benefit of static languages. Certainly, the coder has less work to do. Another benefit is that it makes coding accessible to less skilled people (and more skilled people who have less time to devote to a particular task).

There are trade-offs. The first thing is to note what the trade-offs are. The second thing is to note what groups of people use programming languages and for what tasks. The third thing is to ask how those people value those trade-offs, for those specific tasks. e.g. Perhaps sometimes, a crappy, hard-to-maintain, only partially correct solution now is better than a high-quality, clear, correct solution too late?
Tell me about some of this "pro-west propaganda".
see the news headlines ...

-"Stick Up: Antimatter Atoms Trapped for More Than 15 Minutes" by Scientific American

- "Antimatter Trapped for Amazingly Long 16 Minutes"
by Foxnews

-"Scientists hold anti-matter for 17 minutes" by Radioaustralia
The Peoples daily article didn't deny the threat, it objected with the obvious implication google were making about the hacks originating from within the government.

Why did google choose to publicise the event at all? surely that only tells the attackers to find a new attack vector (rather than thinking there existing vector is still okay).
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The services/apps are often hostile to it, in my experience. For a while I had a mental password-generation scheme that involved commas, and about 50% of websites would reject my password for having an illegal character, sometimes explicitly, other times just breaking in weird ways. After one site let me set my password to one involving a special character, but wouldn't let me enter that same password on the login form, I became wary of using special characters in passwords. (The site was a bank, not some random forum.)
Some important things are missing:

For example in Android development we do not use java serialization but instead use a parcelable interface to store stuff and write to an android OS bundle to pass data between activities, etc as it is somewhat faster than java serialization.
There's no shift key on my game controllers.
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