skysight-inc/HackerNews huggingface dataset:
True, but I don't think those companies pay for those posts. It's all part of the "YC Accelerator Advertising" write-off that funds this site.
This is correct, but just want to add that many may interpret this as a positive sign, it is not necessarily. In many cases, binding antibodies increase cell infectivity. Also, there is some research that indicates the presence of non-neutralizing antibodies without the corresponding neutralizing antibodies and humoral response may be a factor in the development of antibody dependent enhancement. As far as we know, it is the neutralization potency that strongly correlates with disease severity.
Yes but the topic of discussion is rust here. D is awesome, but we are talking about the windows bindings for rust being “just good enough”.
My guess is we will need to FDA approve the mRNA vaccine development platform so we can develop a cocktail of spike mRNA vaccines and you will take 1 or more of them. We will need some kind of rapid clinical trial procedure to get updated mRNAs tested.. I am not sure what they do with the yearly flu vaccine in this regard but a similar approach is necessary. Then we will need a rapid surveillance program as well.

We will also need to update / create more antibody treatments like Regeneron's.

But that's a lot of technology to solve the wear a mask and social distance problem.

We need to keep the fire from spreading because it will just come back and burn down the things it missed the first time.

I suspect we will be dealing with rolling covid lockdowns for the next 10+ years.
> What is the difference between FDA approved and an emergency use authorization, from the perspective of the law?

> Under an EUA, FDA may allow the use of unapproved medical products, or unapproved uses of approved medical products in an emergency to diagnose, treat, or prevent serious or life-threatening diseases or conditions[1]

The difference is that something pushed out under EUA is _not_ FDA approved. So any laws related to approved medicine, devices, vaccines, etc do not apply automatically to EUA products.

[1] https://www.fda.gov/vaccines-blood-biologics/vaccines/emerge...
If that's as a developer in a US city that's pretty underpaid
This is the sort of comment I'm talking about upthread (https://news.ycombinator.com/item?id=25862817) when I say that you perpetuated a wretched flamewar. Seriously not cool. Please stop and don't restart.
I remember downloading GetRight download manager from there. Aeons ago, truly Internet 1.0.
There's more than one explanation as to why "mainstream media" might not run a story. The NY Post isn't exactly known as a bastion of credible journalism. That's why they ran the Hunter Biden laptop story when everyone else passed because they couldn't verify it.
Makes sense, it's clear brain drain has been a big part of their downfall.
Claris FileMaker Server: Now on Linux
Union Square Ventures invested in them a few years back, and blogged about their rationale and some info on where Tucows is/has been headed as a business:

https://www.usv.com/writing/2017/02/tucows/
Wow, end of an era. I guess it realistically ended a while ago, but I remember downloading stuff from Tucows when I was a kid playing around on the internet with dialup.

I was really surprised to learn recently that they own Ting (the cell phone provider) and big domain-related businesses like eNom and Hover. Looks like they're doing just fine.
Yeah, I just think it's a hassle with no value-add to fill in the same forms time and again. Let's say I've researched the offering and decided I want to apply for this specific credit card. Shouldn't it be a one click thing? Credit Karma can tell the bank everything there is to tell about me (with my consent obviously)
This describes our qa team accurately
> 700k paintings

This figure immediately reminded me of a very interesting EconTalk episode[0] on the management of art museums. The premises from the discussion (as I recall):

- Art museums have more than 10x the number of pieces in their archives as they do on display. Some of this art will never be seen by the pubic.

- When art galleries charge admission, patrons feel the need to "get their money's worth" so they rush to see as much of the exhibits as possible, without taking time to thoroughly enjoy anything.

- The purpose of art is to be enjoyed. The above two points make this goal much harder.

The conclusions:

- Museums should be free admission and funded by selling pieces from the archive (really interesting discussion on how this is taboo for curators)

The second-order effects:

- Patrons can sit and enjoy a very small section of the museum instead of rushing through, since they can simply come back for more later

- More people get to see fine art

- Second- and third-tier museums start to gain access to better art, since they can simply buy it instead of waiting for estate donations (which go to larger museums)

I think it's worth a listen.

[0]: https://www.econtalk.org/michael-ohare-on-art-museums/
You shouldn't compare a small and niche community like HN to a website like Twitter.

Twitter is the web equivalent of a public square, where everyone gets an opportunity at a speakers corner, HN is the web equivalent of a club house, or something private like that. There are laws governing public spaces all around the world, like town squares, where people are guaranteed rights to speak. Laws like these need to be adapted to fit the internet as well, asap IMO.

As much as you might like to think that the Town square analogy is incorret, because the protocol HTTPS is the real Town square, and Twitter is really just another club house. (except very big) I also disagree with that, because of the nature of social media and platform monopoly. There will ever really only be one "youtube", one "facebook" and one "twitter", certainly nowadays when these social media platforms have grown to such an extent, covering the entire globe, let alone nations! This is because _the power of a social media platform lies in it being social_ i.e., the place where you find other people.

The platforms on top, stay on top.
Rust has had that for a long time as well. This is first-party support from Microsoft for Rust in contrast to community supported options like in D.
I found this on Wikipedia.

"On 7 January 2021 it was reported that Pfizer researchers had found the Pfizer and BioNTech COVID-19 vaccine in tests involving 20 blood assays to be capable of affording protection against one of the 501.V2 variant mutations (N501Y, shared with variant B1.1.7). Further investigation was to be undertaken to ascertain the level of protection involved."

https://en.wikipedia.org/wiki/501.V2_variant

Which came from this article.

https://www.theguardian.com/world/2021/jan/08/pfizer-vaccine...

But I can't find the original or subsequent studies.
Instacart to cut 1,900 jobs, including its only union roles
Ask HN: How to do online A/B testing?
I’m looking for examples or articles / books that explain mathematical approach to A/B testing.
Interesting! Thank you, think this will be reintroduced?
Sure, but they still wouldn't even be able to imagine some of the things that they could find in a glass of milk.

Presumably a spacefaring civilization would be limited by discovery, not production.
Reminds me of download.com and how that was such a go-to site for me. I still have that in my muscle memory when I open a new tab, along with a few others from my childhood.
This is critical to Twitter's crappy stance. They want to act like a neutral party to avoid liability (like common carrier status of US telco), yet they also want to censor what and who they feel like (via their ToS and being a private company). Their stance is inconsistent and this type of case may lead to resolution of that. Unfortunately I predict they will just add a few illegal things to their ToS as being twitter offenses.
Yep. It's an irresponsible headline, like so many others, renewing panic even amongst the crowd here.

I hope your comment and others like it are not lost amongst all the others so quick to call for a doubling-down of imposed quarantines and lock downs without regard for collateral damage, based on their partial knowledge of the immune system and lack of perspective.
yeah, there's a scissor icon when viewing an artwork and clicking that will give you an option to download (you'll need an account created first). Also, give it like a good 3 seconds after you click it, I noticed it took a while to start the download :/
Only if code is downloaded/side-loaded after the app is installed.

Racket code bundled with the app will be fine.

The gray area is if the app allows the user to create new Racket code.
> Edit:- to the folks down voting me, please show me some major outlets (NYT, BBC, etc) reporting on this. As far as we are concerned, this kind of stuff should be news.

The story is only a few hours old. "Mainstream" media often requires a level of verification that may take a few more days before you see their stories happen.
The internet enabled the dream that we all can be broadcasters, not just big companies.

(In some countries other than the US)
Ask HN: What are some tech communities to follow on mastodon
Functional programming in Python is severely hampererd by Python's lambda keyword, which - simply put - sucks.
On the flip side, you have a sizable portion of the population that feels even the Emergency Use Authorization (EUA) by the FDA was rushed (To be clear, I'm playing the Devil's Advocate here - I personally don't disagree with the FDA's decisions, and got my own shot weeks ago)

Genuine Q: which steps of the process do you see as superfluous? Pfizer announced the end of the phase 3 trials on November 18th, they submitted an application to the FDA for EUA on the 20th of November (or sometime shortly after), and the EUA was granted on the 11th of December.

It didn't take 11 months for the FDA to give the OK. It took 11 months to design a vaccine from scratch, conduct phase I safety trials, phase 2 human safety and dosage trials, and a phase 3 trial to determine efficacy. This includes actual production of the mRNA & its vector in quantities sufficient for the trial, subject recruitment, shipping logistics worldwide to participants, administration of the test doses, data collection, analyses, and compiling results. Honestly, 11 months from start to finish seems like an amazingly short time to achieve so much.
> 16 of them (with 4 x quad SSD adapter cards) in a 2-socket EPYC machine can do over 100 GB/s.

It is more interesting if actual CPU can handle such traffic in context of DB load: encode/decide records, sort, search, merge etc.
> Generally true, but the judgment call on "is this patient better off by being left alone" vs. "is this patient better off by having a surgery" is not easy, especially in our culture which worships heroic medicine. Patients often demand that something be done because they are primed so from the popular media they consume.

That's why it's a problem with professional ethics in healthcare first and foremost. Nobody in the bureaucratic chain is qualified to make or judge medical decisions and them trying would only be a monumental disaster because they don't even meet the patient and they're probably not medical professionals themselves. Hell, the patients and their family are rarely qualified to make the decisions - just look at what doctors chose for end of life care versus what their patients end up doing.

The system doesn't work if we don't police the professionals making the decisions at the point of care. The trick is not overdoing it like we did with opiates, scaring doctors from prescribing them even for patients genuinely in need.
The T2 chip is non-standard and unique to Macs. It affects the boot process and disk access in non-standard and proprietary ways. Apple's SMC is also non-standard, as is their UEFI implementation.

You can see a list of differences between Macs and standard PCs here: https://en.wikipedia.org/wiki/Apple%E2%80%93Intel_architectu...
In Asia, some people are doing this for decades.
There's nothing in that sentence that implies they'd need even 100 IOPS, much less 20 million.
It is easy to understand. Gavin wanted to say what he said. It does not mean that he thinks this is true. He just wanted those words to be out of his mouth. Now how to interpret this fact is another question. May be he wanted to distract public focus from another person. May be he was paid to say so. May be he was bored and did it for lolz.
I thought your comment was a tongue-in-cheek reference to Windows Subsystem for Linux and then I clicked the link.
To understand the economic implications of cryptocurrency, all you would need to know is that it is a decentralized currency that can't be controlled by any one entity and that is frequently used for crime because it is psuedo-anonymous.

I don't see how knowing any of the technical details would make any difference in her expert analysis.
Yes, there’s a growing trend of connecting tech companies to untraditional talent, including in emerging markets. This is for good reasons: talent is everywhere, there’s a growing need for it in the tech sector, remote work and/or relocations are easier than before, and untraditional talent is less likely to be successful going through traditional application processes on their own.

The vision of these organizations is similar, and they take slightly different approaches. For instance, Andela is an agency (they hire the talent) and YouTeam and Andela are both remote-only. We took the approach of helping talent reach their dream jobs whatever they may be (including jobs at companies like Google in Europe) because that makes it possible to attract the best talent, and because ultimately we believe that will have bigger impact.

I’ve seen at least one example in SEA so far: https://pesto.tech/ If you find others, let us know!
Looks like this was posted again, so I'll post my response here as well:

This is correct, but just want to add that many may interpret this as a positive sign, it is not necessarily. In many cases, binding antibodies increase cell infectivity. Also, there is some research that indicates the presence of non-neutralizing antibodies without the corresponding neutralizing antibodies and humoral response may be a factor in the development of antibody dependent enhancement. As far as we know, it is the neutralization potency that strongly correlates with disease severity.
It's in the suburbs of an east coast city. I don't really see higher paying intermediate jobs (switched stacks a few times).
So scaling up instead of scaling out. I’m not sure if it’s a viable strategy long term, at the same time we probably don’t want a single CA to handle too many certificates?
Looks like a very cool product and the price is more than reasonable. Some things that caught me up and maybe others are...

- What is a monitor? Is it a site? Or is a thing that can monitor multiple sites?

- Can I monitor multiple pages of the same site?

- I'm generally put off by time based trials, I get irrational fomo, maybe now isn't the best time to trial it, I can wait until when I am going to use it more (reading from work).
I'd like to clarify that my position isn't about "not understanding regular expressions". Sure, it could help people who don't. But even for people like me: I read the O'Reilly regex pocket book and other materials, I studied formal regular languages during college, built a basic lexer/parser for a senior project, I've written no shortage of simple and complicated regexes in application code in the workplace, and once in a conference lecture I was the first audience member to recognize and shout out when the speaker quizzed which commonplace file format the given gnarly full-page regex matched.

I'll never be up there with Brian Kernighan[0], but I know my way around regex at least as well as what I feel is reasonable to expect and accommodate from the average developer.

My position is that even with a background in regexes that's a lot deeper than just Googling and putzing on Regex101.com, traditional regex syntax is still a frustrating time sink that's hard to get correct without more trial-and-error than feels intrinsically necessary. The syntax provides zero opportunity to discover there's a more effective way to perform a task. I have trouble identifying a compelling value proposition for traditional syntax besides familiarity and natural serializability, and the fact that it gets the job done at all.

I don't believe traditional regex syntax is the optimal way to accomplish text pattern matching tasks in the workplace, and I'm open to other tooling that makes it success simpler and more reliable. People misuse regexes all the time (examples like the one you linked are almost tropes at this point), but I don't think that's compelling justification on its own for preserving the status quo.

[0] https://www.cs.princeton.edu/courses/archive/spr09/cos333/be...
The notion that you’re live on video with others in the virtual space (instead of say, representing yourself with an avatar) creates such a surprisingly special experience. In this way, I think Pluto subtly and beautifully mirrors what real world interaction actually feels like. Excited to see where this project goes!
Here’s the lawsuit brought by the National Center on Sexual Exploitation:

https://www.scribd.com/document/491614044/Doe-v-Twitter
Downloading Winamp from Tucows so I could listen to illegally downloaded NOFX mp3s. The good old days when the WWW was so new and exciting for me.
This will probably go about as well as Feedburner's RSS ads.
That's not true. FB has many US moderators, many outsourced to other companies.
I always get a kick when businesses do exactly what the numbers said they would do and other people act surprised.
The Very Large Array (VLA) could pick up a broadcast from a geostationary communications satellite at a distance of 0.14 lightyears. The planned Square Kilometer Array (SKA) would be able to pick up the same signal within 500 lightyears. A radio telescope with detectors on opposite sides of the earth could pick such signals up from 2000 light years away. The nearest 2000 lightyears make up 0.16% of the milky way galaxy.
I meant the article comments as you discovered.
It is quite likely unless you've meticulously avoided it that MySQL is using ISAM on-disk temp tables in the service of your queries.
Yes, I went from audio coupled 120 baud BBS in 1983 to the 56K by 1993 and loved Tucows when they emerged. Many happy years spent learning at their knee - as others have said, Thanks, Tucows - live long and prosper in whatever internet sea you now swim in....
That's exactly what this is, a way to sink their proprietary claws into Rust and try to influence the market the way they have done with most of their software for decades.
Sure but what are you going to do with those technicians after they've installed the hardware in a sparse region? It takes a lot of man-hours to do the install, especially for long distances that are rural homes, but not so many man-hours to maintain
Linux Kernel Virtual Routing and Forwarding (VRF)
>Where I worked in R&D the doors were constantly revolving and many people admitted they wait to register enough of prestigious time at Intel on their CV to get hired at a much better rate for another company.

>Rehiring retired people to me signals the new CEO has no trust in people that are already there.

And why should he, given the conditions you just outlined? I certainly wouldn’t. They’ve demonstrated they can’t advance either the process tech or the chip architecture in any meaningful way.

And I don’t even fault the engineers, but rather a finance-oriented CEO who managed for the bottom line, to goose stock prices and executive comp, while cannibalizing the engineering corps of the high-output talent and experienced technical leadership and mentoring necessary to advance one of the most complex, difficult technologies.

One possibility here is that Gelsinger is reversing that, rebuilding the original proven team from the top down, starting with the people who both know how that works, and have the connections to and respect from additional top technical talent to bring them on as well.

If Gelsinger also restructures compensation for these folks to ensure they’re appropriately compensated (way above “market rate”) then that’s confirmation that this isn’t panic but the right strategy of rebuilding Intel’s talent base.

And that report you linked was discussed yesterday, unclear how reliable it is:

https://news.ycombinator.com/item?id=25844959
You may want to read that article more attentively, because it does not support your claim at all.
> It's you forcing me to accept your definition of "factual"

Do you have a link to this definition that doesn't match your own? I'd be curious to see varying definitions of "factual"; it might make this issue easier to discuss.

> it's no longer my choice, the gatekeeper chooses for me what is "fact" and what is not, and I have no option of applying my own intellect and make my own choice - the choice is made for me, the conclusions are prepared in advance for me and the information is pre-filtered and pre-arranged to push me into accepting whatever vision of the world the gatekeeper privileges

You use two words here: "pre-filtered" and "pre-arranged"

Pre-filtering is not what's been proposed in the article. We've already covered that above, so lets not reiterate... any implied pre-filtering here is imagined.

Pre-arrangement is the world we live in and the very definition of the modern internet. What's been proposed is to introduce an improvement to how things are pre-arranged. I'd love to live in your utopia where we have the time to read everything in Google's index one-by-one and select which ones we value individually, but here in the real world, things are pre-arranged. This is about trying to find the best way to ensure that that pre-arrangement is not horribly skewed and corrupt.
>We are as entitled to it as we are to the Linux kernel on which it's based.

>That's the cost of building a product on GPL2 licensed software.

You are only entitled to the GPL code if it is distributed to you (as in you are a customer).
Can you elaborate on this? What is wrong with Python's `lambda`?
This is a strange argument.

Government departments dedicated to planning are often required to publish their guidance/research publicly making it difficult to get away with cherry-picking metrics.

Having a team of professionals who understand the basics of our economic system tackle the problem seems to have a higher probability of success as compared with business leaders who often lack formal training in statistical methods.

There are more arguments but this should be enough to prove this false equivalency.
Back on May 23 2006, a sortable column of GZip source code size measurements:

https://web.archive.org/web/20060523195137/http://shootout.a...

https://web.archive.org/web/20060519213743/http://shootout.a...

> Performance in a compiler is usually taken to be a combination of runtime, code size, and compile time

The benchmarks game shows source code size, not compiled code size.
For unsteady contracted project work, this doesn't sound off the mark for high-value niche skillsets at a senior or principal level. I wouldn't expect FAANGs to pay it for steady work, though.

Well, Netflix might come close. I can count two principal-level architects pulling north of 700k/y, but I doubt they work just 40 hours a week.
Timbeter provides data that helps get a more accurate reading of timber stocks
I'm curious what the cost would be to run this type of hardware at any cloud vendor? Does it even exist?
He should either be thrown in prison for contempt of court until the keys are revealed.

Charged with perjury when he tells the truth to get out of court-jail.

Or committed to an institution because he is mentally unfit and that it would be unconscionable for him to face penal consequences for his delusions.

None of this is happening and the judge is clearly entertained.