skysight-inc/HackerNews huggingface dataset:
There are a lot of companies (including mine) that have been working on personalised, target, combinatorial, interfering, etc. RNA therapeutics for quite some time. The success of RNA vaccines in the last year has really opened up the potential for pharma partnerships to test and develop these kinds of things. They have built out the infrastructure and there's a broad confidence and awareness of the basic concepts that was previously largely missing. Pharma just really loves proteins.

The next 5 years are going to be incredibly exciting - it has the potential to fundamentally change humanity's relationship with many kinds of disease.
GoDaddy when we have domain problems: sits around not doing shit

GoDaddy when they can milk some PR: URGENT! ALL HANDS ON DECK!!
It will always be cheaper to not use the blockchain for storage - most things aren't critical, sensitive or important enough to necessitate being stored in such a way.
> Even after removing cases occurring within 7 days of vaccination (409 on Pfizer’s vaccine vs. 287 on placebo), which should include the majority of symptoms due to short-term vaccine reactogenicity, vaccine efficacy remains low: 29% (see footnote).

The 95% claim assumes you've had both doses and five weeks have passed since the first dose. I don't think that's a fair way to dice the data. Also, "covid-19 symptoms" (the proxy that opinion writer used) are very non-specific. Headache, sore throat, cough - there's myriad causes. That's why PCR+ is the only way to get a decent signal.

This seems like a crackpot analysis, not that I'm an expert.

Oh, and finally, relative risk reduction (that number you're quoting) is a fundamentally different property than efficacy. It's the difference between the placebo and vaccine groups in catching covid. Relative risk reduction would only equal efficacy if 100% of the placebo group caught it.
Silencing Trump: How 'big tech' is taking Trumpism offline
You spent 10 years on this?

Was this like a side project that you paused on for years? 10 years is an absurdly long time to build in the dark.

Did you do any market testing or let people besides you, your friends or family use it? You could've just wasted a lot of time building something no one wants.
Epic Addresses Calls to Deplatform Dozens of Online Communities
Agreed, like that it was prefilled, but just a note the article for Paul Graham is "The Bus Ticket Theory of Genius".

But the image that came up wasn't for a bus ticket, it was for a raffle ticket, which basically has nothing to do with a bus ticket except it has the word "ticket" in common. So on one hand it kind of highlighted what I don't like about services like this in that you get relatively dumb results that are basically just doing keyword matches, and the images actually have nothing to do with the story.

Edit: OK, actually none of the images really make sense. Since these are curated results I'd expect them to show the best of what can be generated. Instead:

- TechRadar, Apple's privacy labels reveals Whatsapp and Facebook Messenger's hunger for user data: Show's a Samsung phone

- AVC, Temper Tantrum - AVC: Maybe, kinda fits, but looks to me just like a sad little girl, not a girl having a temper tantrum.

- BBC, The nuclear lighthouses built by the Soviets in the Arctic - BBC Reel: OK, this one fits exactly, but the image is just taken straight from the blog post.

- Medium, I’ve Been in Venture Capital for Two Months. Here’s What Still Makes No Sense: A completely random picture of a forest.

- Pulse, If There Aren't Any Typos In This Essay, We Launched Too Late!: A somewhat bizarro picture of someone on a scooter with a rocket on their back.

TBH if I wanted to promote my blog post I'd just do my own stock image search and use that instead.
never understood whar extra features people need out of a terminal that they are building new ones. heck there are electron based terminals
I use xterm because it's one of the only terminal emulators that allows me to disable the alt-screen (titeInhibit). Apparently I'm one of the few, but when I vi/view a file and exit, or read a man page and go back to the command line, I still want to be able to reference what I was just looking at.
Trump's Maga insurrectionists were perverse US civil war re-enactors
Not quite true. He used it as proof of gods existence. But his logical premise holds, and has yet to be countered in any meaningful way. Our awareness of our existence proves our existence.
I agree that initially, when the danger posed was unknown, a quick and temporary lockdown was justifiable. And indeed, you seem to be describing a sounder response taken in AU, overall.

However, somewhat in defense of the OP, now that we have a good idea of who is vulnerable, as well as the enormous relative health, social, economic, and personal costs that the lockdown has caused to many who don't have the luxury of a desk job, the claim that the lockdown is no longer justified (and hasn't been for some time) is very justifiable. Sadly, incompetence and political maneuvering have taken center stage.
I've played speed chess for years, and I have never hit 300 moves in a game. The only way this will ever happen is if both sides are intentionally trying to avoid 3 move repetition.

And in terms of premoving, chess.com spends 0.1 seconds per premove whereas on lichess it's instantaneous, so I've found games tend to last longer on lichess move wise.
It's definitely overkill, but what is a homelab if not overkill? It's not really high maintenance, though. Once it's in and running you'll never have to touch it.
I have vouched for dead initial comments too, but usually there was a clear reason they were like that, like a link.
People can have such different lives.

The opposite of anger is not calmness, it's empathy.
I am curious how a trial for the HIV vaccine will proceed in a world where PrEP is available.
Exactly, it’s a smuggled assumption. A standard deviation is the second moment of a normal distribution. A negative binomial is a much better model for count data: https://statwonk.com/poisson-gamma-negative-binomial.html
> I think machine learning people are just using fancy excel formulas.

I mean... you can do it in excel it is just a lot... slower - you can do like anything in excel

https://youtu.be/s105jek4WUI
On Transitioning from C# to F#: Rethinking State
Deglaze. Heat it back up and add water. This should become less of a problem the better your seasoning is.
I think the idea is the mRNA vaccines are much faster to produce which makes it easier to keep up (but I could be wrong, this isn't my area of expertise).
You're trying so hard to disbelieve it when you obviously believe it to be true. It's not my job to participate in your pretense, to give you "proof" to validate your chant-like self deception, "i cannot believe it because there must be no proof"
So, any reason he can’t just have an instance of his own? He wasn’t really banned from Mastodon at all, just done guy’s instance...
I think it's entirely possible that de-platforming will actually have the effect of de-escalating. It's like putting a child in timeout: it gives the child a moment to cool off before resuming normal activity. Clearly people's passions are inflamed at the moment and they were feeding off each other's anger. Some time off may allow cooler heads to prevail, even if it's just the time it takes parler to set up an alternative infrastructure.

Of course, I may be completely wrong about this, but it's not clear to me that this is a worse option than doing nothing.
Redox is cited in their OSDI paper. Basically they have a bunch of new ideas for writing an OS that are implemented here; Redox is only similar because they're both in Rust.
I went the open source route - I was on H1B, so I couldn’t make money out of it anyhow but it has very helpful in validating the project. Most employers support open source projects.
Well yes it's based on trade. As long as there are things I want other people to create or do for me I'll be willing to do or create things in return.
You may also be misrepresenting opinion on school prayer (but it may just be a wording issue). From following link, only 41% support teacher-led prayer https://www.bostonglobe.com/ideas/2019/10/04/big-data-studen...
> I would

But you’re posting this from a throwaway?
> The detectors themselves introduce the quantisation.

Which, if you are going to take this position, applies just as much to neutrons as to photons. The only evidence we have for either of those being "particles" is such detections. So either you should withdraw your claim that neutrons are particles, or you should admit that photons are. You can't pick and choose.
Science is not about being right every time. Stating a hypothesis publicly as you're experimenting to determine it's validity shouldn't require a wager.
It's even more trivial with CenturyLinks Fiber. You don't even need any certs.
You may find out just how much your data is worth on the market. I’d love to see the option of a subscription in more places, like FB itself. They’d still be serving ads and making money off that.

Their costs would go up, they may balk at that, but I expect it’s trivial given their profitability. Wonder how they’d price “private-mode” properties.

More importantly: do you trust FB to stop selling your data when they take your money?
Agreed. It’s still too complicated to run a personal website. “Social media” is a UX layer over web hosting.

There’s no reason a Facebook like experience can’t be created using a domain registry, hosting, an RSS/atom feed, and a friend request API.
Thank you for your response!

Some people on the right (and a very few on the left) would view being armed as the natural state of free people. Especially when discussing suggestions from righties, it seems like "bring your firearm" is right next to "don't forget your keys".

I think that's one of the issues that really worries me about all this: the cultures of the left and right are different enough that the left views behavior the right considers normal to be violently deviate, and then the right (at least on my own social feeds) reacts as though the left is targeting them personally.

My best argument that no insurrection was intended by those present is that the bombs (or bomb-making materials, or whatever) that were found weren't used, even though the mob had control of the Capitol building. Indeed, even though a significant percentage of the rioters were likely armed (see above), the only shots fired were by Capitol police. More than anything else, that confirms for me that the mob didn't arrive with the intention of taking the Capitol, or insurrection, or anything like it. They had the materials available to make things much, much worse, and instead they acted like tourists. Why? Clearly (I think!), because there was no intent by 99+% of them to do anything but show up and support legislators in finding the courage to dissent from what the Trumpists believe to be fraud.
Facebook says it’s blocking posts with the phrase “stop the steal”
I don’t think that’s a fair comparison. When you get the ad, it’s labeled as an ad and you still get the organic result. “I feel lucky” doesn’t send you to the ad.
E INK plans on adding ACeP to e-readers in 2021
Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?
TIL that bats are an indicator for transmitting viruses
Bad people on both sides, you might say...
As another response suggested, your responses strike me as very familiar coming from a place with diagnosed ADHD. It’s possible you’re responding to dopamine deficiency (and responding positively to dopamine reception).

There being so much overlap between ASD and ADHD, it’s worth considering seeking a diagnosis and seeing if you might respond well chemically to treatment.
Any quantum particle can be used in the double slit experiment. It doesn't have to be photons. It's been done with electrons, neutrons, and even buckyballs (Carbon-60). So whatever is going on, it can't be as simple as "a field is created that photons respond to", because it's not only photons that show the pattern.
If you want no colors with xterm?

xterm -cm
What even is an “average news consumer”?
Sure, but who do you know that’s willing to get 100 flu shots in a year?
Isn't it sad that right to repair needs to be framed this way?

I mean, it's fine to look after the environment.

But...

It seems impossible to ask for individual rights. This is after all an individual right. My right to repair something that I paid for.

But...

It's presented as a collective benefit, the abstract save the planet thing.

We're nothing important unless we're a part of the collective. Or even worse, some abstract idea like the purity of our Precious Bodily Fluids. I'll go to sleep now.
:) I've always have had a soft-spot for language-based designs. It's the only way we can get fearless refactoring throughout the stack.

If I may plug, check out https://internals.rust-lang.org/t/dogfooding-z-build-std-in-.... I'm it can heave us over the fence for the types of things that will make having a no_std cargo ecosystem easier.
> Few people care to repair Android phones because you can't upgrade the OS after 2 years regardless.

This is a mistruth (add: unintentional I'm sure) - and I hope people stop repeating this. I'll explain in detail.

1. Older versions of Android aren't crippled in the way an older iOS version is. On iOS for instance, Safari is tied to the iOS, while on Android none of the apps are tied to the OS version. Any phone running Android 7 (or maybe even 6) would run the most Google and non-Google services without any problems.

2. Most good Android phones such as those from Samsung or Google get 3 years of updates. If you have a Galaxy S8 from Apr 2017, you're still receiving updates in 2021.

3. Finally you have LineageOS. If you choose the phone correctly, you can potentially have very long term support with the excellent LineageOS. Now this isn't everyone's cup of tea, but for most people on HN it's fairly trivial to do.
Thanks for making this service! I'd be more interested in it if there were a weekly option that just rolls up the most important stuff from the week instead of daily - I try not to read the news everyday for my own sanity. Is that in the works at all?
What's the claim here, that there's some line of code in search code that manually specifies Youtube to be higher than Rumble? Otherwise what does "rigging its search algorithms". Is it rigged if Google is giving the user what they're much more likely to want?

If I search "rumble big tech censorship", the rumble video shows up before Youtube. For other queries, why would they expect some random small video site to show up higher than the #1 video site? The article is behind a paywall, does anyone have more details on the claims here?
Indeed, it seems the longer we run under the status quo the greater the cost in externalities, to the point we’re beginning to understand represents an existential threat globally.

However we also risk a self-fulfilling prophecy if we commodify those externalities and reduce them to lines on a balance sheet. I know that this is not quite what’s being argued for, but I am equally certain that is how it would land in practice.

I’m not convinced re-framing/codifying our social, environmental, and human capitals as financial instruments is any kind of progress towards salvation, rather it’s a doomed attempt to take everything that never fit inside the tidy box of capitalism and cram it inside of the box anyway. A try at making the world comprehensible to a mind accustomed to that manner of framing.

This problem needs novel thinking, more novel than finding a direct way to account for it within the existing framework. I regrettably don’t have a better idea.
Doesn't that lead to a very simple DOS on your competitors? Just register a trademarked entity in another market.

Google Soap. Parler French School. Stripe Flags. Square Foods. etc.
Free forex trade copier service
Learn about Azure Monitoring and its basic concepts in this complete guide. Get the answer to all your questions related to the Azure Monitor.
> The burden of proof is on those claiming minds and computers are the same thing.

I never understand this argument. IMHO the rest of your argument seems to obfuscate something rather simple... your brain is a physical object. The atoms that make up the neurons, glial cells, etc. are real and are governed by physics. Are you saying that what you think of as "you" is made up of more than these physical ingredients? To me that would be invoking something "magical" and would thus bear the burden of proof.

> You can have concrete green triangular objects in the world, but not triangularity or green as such...except in a mind that is able to abstract universals from particulars

Why can a sufficiently powerful computer not conceptualize these things? How is that fundamentally different than what goes on in your brain?
I guess, I mean that’s the tails-you-lose of it. It does feel as though somebody’s bought up all the printing presses, and in the face of scrutiny for doing so is disrupting swaths of the opposition party’s press apparatus as the incoming party takes over. I mean Amazon isn’t any ol’ business, but one with great reach facing historic threats of regulation.

It just doesn’t feel like the right thing for our republic. It feels like foul play, and I guess my recourse is at the ballot box.

I guess I think the points raised here and elsewhere about what businesses can do are specious. We still try to keep things fair.
USA Karter Warehouse
You can put more than one drug in a single shot. The MMR vaccine contains Mumpsvax, Attenuvax, and Meruvax to fight the mumps, measles, and rubella, respectively
so cathartic...
I think OP means one shot with a lot of strains in it.
Not sure if this is a flippant response, but I believe the parent post meant 100 strains in one injection.
US BLS, Census, ad NCES have comprehensive stats, with summaries at Wikipedia,[1] and whilst in overall numbers you're probably correct, there are some counterarguments.

- Through the 1960s and possibly early 1970s, a solidly middle-class lifestyle remained possible without a college education. Apprentice and vocational tracks were abundant and viable.

- US Census data show a Bachellors-level local maximum attainment of about 25% in 1977, not exceeded until the mid-1990s.

- Many (though not all) who wanted a degree could get one. Money certainly wasn't the barrier. Yes, it helped (a lot) to be white and male, but former income and class barriers had fallen. By the 1960s, most undergrad programmes were fully co-ed, by the 1970s, graduate and professional. By the 1980s, both were female-majority in many schools if not outright overall.

- Debt loads on graduation were effectively nil at public schools. It was possible to study, work part-time, and save a little. On graduation, options were far more open for exploration, public service, volunteering ... or hedonism. This was a high point for Peace Corps work.

- Grad school was opening up tremendously.

- Academic positions for those grad students were numerous, in large part due to the rapid campus expansion.

Today's colleges deliver more graduates, both absolutely and as a fraction of population.

But as with automobiles and smartphones, what was once an optional luxury has become a necessity: many basic jobs request (though not all require) a degree. Debt loads are crushing. Secondary education quality is widely perceived as lower, and graduation rates there are effectively unchanged from the 1950s (whites) or early 1970s (all). What variation does exist largely trades graduation rates for aptitude levels.

There have always been some graduates who wind up in jobs that don’t require a college degree. But the share seems to be growing. In 1970, only 1 in 100 taxi drivers and chauffeurs in the U.S. had a college degree, according to an analysis of labor statistics by Ohio University’s Richard Vedder, Christopher Denhart and Jonathan Robe. Today [2013], 15 of 100 do.

http://www.bloomberg.com/news/2013-06-25/why-are-so-many-col...

So ... yeah, today more people get a college degree, because they must, with possibly worse quality, far higher direct cost, and more constrained options.

Is this really progress?

I'd explored dimensions of this topic a few years ago, output here:
https://old.reddit.com/r/dredmorbius/search?q=education&rest...

________________________________

Notes:

1. Try NCES: https://nces.ed.gov

Article:
https://en.wikipedia.org/wiki/Educational_attainment_in_the_...

Plot:
https://en.wikipedia.org/wiki/Educational_attainment_in_the_...
> Real science is about one thing and one thing only. Money, aka grants

no.
The social web should be different now
There is a Netflix documentary called Pandemic about couple that is trying to eradicate flu. They found vaccine that works on all flu viruses but it takes 6 shots to work. That’s not practical at all therefore it’s not on the market yet.
For future reference, 'xartutil --erase-all' in Terminal in macOS Recovery erases all data in the Secure Enclave, including the keys used for disk encryption. In that way, it can be considered equivalent to a secure erase command on a non-Apple SSD, except Apple can be trusted to have implemented it properly unlike normal SSD vendors who have been caught implementing it as a NOP.

Also, in my experience, Apple does not require returns to have a working OS installation. You can erase and return in that state.
IBM i (OS/400) has had single address space, tagged pointers, and an number of other "novel" things in the loop for eons. Many people interact with it daily, indirectly, in most of your big box retail stores (think stores like Costco, Lowes, etc).
Please elaborate on why you find it to be clear, simple, obvious!
Yeah, it's very difficult to predict which are going to be the dominant strains so they take a best guess, include the several candidates that they expect to be most virulent that season and ship that as the "flu vaccine" that season.

The hope is that with a much faster time from approval -> production, in theory we could reassess in October / December / February and vaccinate against the most virulent strains that are actually showing up in populations. There are reports that Moderna had a vaccine developed in two days once they received the sequence from researchers. If they or similar companies received "platform" approval to ship new vaccines with abbreviated testing, it could dramatically change how we vaccinate for the flu.
Their live commentary is surprisingly entertaining as well.

And they have a bunch of chess variants to mix things up.

All around impressive site.
Get closer to in the money. Also look up the penny program symbols. SPY is frequently a penny wide spread ($1 per contract).
In the late 1990s/early 2000s some folks got textbooks to put stickers saying “evolution is just a theory.”
Amazon Echo Flex: Microphone mute button appears to be real and functional
OTM, non penny program symbols is my guess.
I fully agree with you and this just proves the point. If everyone was thinking for themselves from first principles or even just using their memories they'd remember which side of the immigration debate they are supposed to be on. You don't even need to go back that far, up until Trump the right wing were very pro immigration because their industries rely on a steady flow of cheap and under-paid and exploitable labor. Exactly the thing the left are traditionally against.
Yet nearly every serial terminal from that era tends to struggle to handle text at >9600bps without some form of flow control at some point.
I didn't know about PrEP, but from what I've just read it has to be taken daily in order to be effective. A vaccine could be a safer method.
Know when the backlinks you are building is removed or changed