skysight-inc/HackerNews huggingface dataset:
Wow. A troglodyte on HN manages to get top votes by vomiting an incredibly incoherent spew of libertarianism, marxism, reactionary nationalism and militant western chauvinism. All of this in reaction to an article about slave labor going into every fanboy's favorite screen. Who woulda thunk it.

A lot of things you say are right: If Western civ actually held to its neoliberal values then things would cost more. Slave labor is inefficient (although it's more efficient and apparently more acceptable than executing people like they did during the Cultural Revolution).

But on what planet do you live where the only solution is armed violence? First of all, that's just not possible. Even in America, the idea that because we have guns we are able to stand up against oppressive government is nothing more than a wet dream fantasy of the far right. In China? Uighurs are going to arm up and stand to the CCP? Are you out of your mind? If that looked like anything, it would look like Islamic terrorism.

You and I in America, and the people in Hong Kong, and the Uighurs, are not in a "slave society", we are in a corporation. And our issues are not going to be cured by taking up small arms against nuclear states that act as part of that corporations, even if millions of us are armed. The only thing going on here is a battle for scarce resources, disguised as a bunch of ideologies.

Look, the UAE and Saudi Arabia have trillions of dollars they could spend to build up a Palestinian state rebuild Syria or help the Uighurs, but what do they do? Make arms deals with Israel and America and China. And logically they're doing what they need to do. There is no world in which your fantasy of small arms and liberation of slaves is a remote possibility.

The only possibility is people owning their own local resources. And not sharing them as marxists, either.

There are very few, if any, levers that we can pull from the West at this point to promulgate that strategy. We can't bomb the railway lines into the Uighur camps, as we should have in WWII, because it would cause a nuclear war. We can cut off trade, and encourage people not to trade with bad actors, that's about it. Everything else is just a wanker fantasy.
I’ve had changes go through, but sometimes in a monkey’s paw way.

I ask the labelling of a school on the map, specifying the name and providing the home town site as proof (a page listing all schools with their adresses and picture), and two days later it was labelled as “<Name of the town> school” completely ignoring the provided info and making the spot misleading. Requests for correction a few months apart didn’t do anything at this point.

So I can vouch for the process sometimes working, and I have nothing to do with Google. Now, why, when and how it works is a complete mystery.
"Big Pharma" needs to make a profit from somewhere to finance r&d. 9 in 10 drugs (warning, made up statistic alert) don't reach the market, or something like that. And then they need to spend money on manufacturing. Then of course you have 'generics' when the drug is out of patent and other companies can produce it without royalties.

From the BBC article(s) I believe the UK has ordered 100m doses. I have no idea who is producing those though, and how long it takes.
It's still slow. The reason it's slow is because they use a complete SAT solver to do the resolution. So, it's slow, but it's also thorough. It gives some insight into why pip's dependency management is not thorough: they're clearly sacrificing completeness for performance.
How can people like you still exist and persist with their narrative of downplaying the pandemic?
There‘s whole books on numerical simulation with Excel. Which is absolutely incomprehensible - if you are math-wise enough to do simulations, you should be computer-wise enough to use a real programming language.
Difference Between Population and Sample in Statistics and Machine Learning
The ducting 'shadows' the blade during forward flight, massively reducing efficiency. During hover they can help though.
They were very open about their desired outcomes alongside their releases. They had the express goal of affecting the election, as expressed by their site and their twitter.
I have two of these venerable calculators gathering dust in a drawer, the 11C (scientific) and the 16C (programmer). Thanks to these devices, I learned to love RPN. I still prefer RPN mode when I use the various Calculator apps on my laptop.
In a world where there are three players, culture and reputation are not worth much, if not only at the beginning. Maybe 5/10/15 years from now the software and competencies to manage bare metal will be only behind the doors of those three companies, and at that point it will be economically convenient for them to act as a cartel and increase prices.
hooray for hashes!
Hah!

I bet in the mind of a bank exec, it may very well. An amusing point.

There are laws in some countries preventing this, but your point is entirely valid and even makes me wonder about opting out.

Heeeey, wait a minute, is this some banking MILDEC type scenario? Who are you? (j/k)
its also abuse of statistics - that 10 times likely includes clapped out old beaters.

How about compare to cars of the same age?
They literally tweeted that their goal was to fuck her over.
5 Steps to validate your business idea
On my side, Firefox Android, it is verified as "Cloudflare\, Inc", which looks even more suspicious
Exactly. I expect and assume everything with the highest standards and outstanding research and development with anything having the 'Oxford' name.

But when I see '<70%' effectiveness compared to 95% effectiveness with the Pfizer-BioNTech and Moderna vaccines, the Oxford-AstraZeneca vaccine looks very disappointing and far from the top standard I have expected.

That is not good enough.
It’s interesting how the vaccination speed affects epidemic. What’s the effect of vaccinating everyone within a month vs within half a year.
> EDIT: The mRNA vaccines are obviously not therapeutic antibodies, but they probably checked for cross-reactivity of the engineered spike protein as well as the generated antibodies using similar methods. I’m not 100% sure, though.

There is a study[0] showing cross-reactivity between SARS-CoV-2 antibodies and other human tissues, thus predisposing the host to autoimmune diseases. This should apply even more so to any vaccine since vaccines produce a more robust immune response.

Phase 2/3 of Pfizer-BioNTech did, however, include people with autoimmune diseases [1]. Other vaccine trials did not, as far as I am aware. This does not really shine a light on pre-disposition to an autoimmune disease 6-9-12 mo down the road.

Reading this comment again before I post made me realize it sounds very gloomy, so I feel obliged to say I'll be getting whatever vaccine I can get my hands on at the soonest possible date.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246018/#__ffn_...

[1] https://www.fda.gov/media/144245/download
It’s not clear if the vaccine will prevent infectiousness yet, unfortunately, so for now it’s best to assume even vaccinated people can spread the virus until more is known. Both ways will increase herd immunity.
I've been using Retool for a couple weeks and it's pretty impressive.
How to Organize Your Knowledge?
The most detailed public reports I've seen are:

https://www.fda.gov/media/144245/download (53 pages)

https://fda.report/media/144673/Moderna+COVID-19+Vaccine+rev... (61 pages)

I think the actual applications had a thousand pages or so, but I haven't found them online.
41 minutes of spirited flying with hobby components weighing under 250g:

https://youtu.be/u2v1QLmhNxM
Homes Built from Aircrete Are an Affordable and Ecofriendly Option
The least harmful thing you can do is to only buy refurbished devices and to use them for as long as possible before replacing them.

You'll have to choose to get off the constant upgrade carousel.
If this is about the MC form, I found that if I pasted my CC number (such as from a pass manager), it would bork unless:

- I entered the number

- Then moved to the front of the input field

- Deleted a char, and re-entered it, because

- an end-of-field char change removes the whole number

Wait a sec, even two seconds, and the number will auto-obscure.

Then it works.
No one has at any point said that the goal is for everyone to have the same amount of wealth, so I'm not going to argue against, what's clearly a straw-man

For your last point I'll have to go with a "citation needed"

The Scandinavian countries and many other European countries in general, have a high level of wealth redistribution and have higher education levels, higher voter turnout, less crime, and higher standards of living than the US
This is the type of vaccine that can end the pandemic. Cheap to produce, cheap to distribute, old well-understood technology.

Also many countries have the capacity to produce a similar vaccine. For example here is a feel good story from RT about Venezuela buying Russia's similar Sputnik vaccine:

https://www.rt.com/news/511063-sputnik-vaccine-venezuela-dea...

10 m. doses to be delivered within 3 months. How long time would it have taken Venezuela to procure a similar amount of mRNA vaccines from Pzifer or Moderna?
The biggest speedup factor was how easy it was to get people sick. A certain number of people had to get sick within the trial groups before results could be conclusive. With how widespread COVID is and how many people caught it, they hit that requirement significantly faster than they normally would.
> hold Apple and their executives criminally responsible

What crime was committed?
Edge et Service Mesh, maîtrisez le réseau de vos applications avec Denis Jannot
A while back (probably last winter) I was driving a truck that needed a new thermostat, in what I thought was fairly cold weather. Reading TFA, I understand it wasn't really so cold. As long as the heater worked, I was fine. As soon as it started blowing cold air, I knew the thermostat had gotten stuck in the wrong position again. I figured out that I could simply slam on the brakes to solve this problem. In this fashion I was able to drive about 25 miles to a mechanic.

The truck had a functioning radiator and appropriate coolant levels. The only thing wrong was the thermostat. Even in that configuration, the temperature gauge climbed into the "danger zone" if I neglected the brake-slamming trick.
I see recommendation very regularly here. I use Gandi.net and they are great, but I also regularly see namecheap being recommended (I never used them though, in my book "cheap" means low quality ^^ I'm French and the English word is often used that way :) )
The Bibliography is definitively useful but the editing and commentary is really good too. I'll bookmark it and will keep reading later.
So because only the 2-full-dose trial had large enough N, that's the one that's approved, so people will be given what is most likely 60% protection even though it's possible, likely even, that if the person administering the vaccine simply doesn't inject the whole first dose - the protection will be higher? What will happen when the 0.5+1 dose trials are finished? Will the dosage recommendation simply be changed then?
Oh, man. Hard to watch the sequence starting at 1:56 without wondering when the robot is gonna take that guy's hockey stick and beat him to death with it. Do you want a robot uprising? Because this is how you get a robot uprising.
The secret to MS success was that they realised their main customers weren't the end users, but corporate IT and ISVs.
Presumably they also counted the numbers of cases with symptoms in control and experiment? I assume the ratio there was also not as favourable as in the mRNA vaccines?
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1.0 of Git was actually 2005.
Ask HN: Leave Tech for Unique Domain Expertise?
I work in a large enterprise tech company where I am a tech lead for large distributed systems. I earn less than FAANG but certainly make good money.

Because of my experience in my industry, I've gotten an opportunity to become a technical adviser at a regulatory agency in my field. This adviser roll is brand new (I'd be one of the first hires for this new team), will pay me very well, and represents an opportunity to become an industry expert a la broad domain expertise working with the biggest players in the industry.

I'm a tech guy so its hard to leave technology delivery, but over time, I do want to become more of a product guy or even work my way into sales, so this type of experience seems perfect. To become an industry expert seems like it would really give me an edge when combined with my technical skills.

What does HN think? Will this industry expertise be worth it? Or are technical skills more worth it in the long run?
They have in many ways been more rigorous and transparent than other vaccine trials (weekly swab testing of all subjects, publishing the paper first rather than in the media first, being honest about mistakes made). They don’t control the media reporting.

That said it seems the group who received smaller doses by mistake was only 1300, not sure where they got the data on 12 weeks but presumably it’s also a small number or they’d be going with that for everyone.

Things should become clearer over time and I hope they can shift to the smaller doses first as it’d give us double the number of initial vaccinations when supplies are limited.
I had the least problems with porkbun so far.
It's amazing to me they see a puppet. Do they call a car a puppet? It's controlled by a human. The robot spot is hardly what I'd call a puppet, for instance.
> With Moderna one, some people are loosing antibodies with in weeks.

That's... how vaccines work? Your anti-bodies don't stick around forever, and they're not supposed to. The purpose of the vaccine is to prime your memory B/T cells so that when the actual virus is introduced to your body the antibodies are produced much more rapidly, enough to kill the virus before it can take hold.
I assume you are referring to the approval process. I've been thinking that too.

I don't want to be that person who thinks a really complicated thing should be trivial, so: Can anyone suggest why it would take weeks to approve these vaccines? What might the regulator actually be doing in this time?

They're clearly going to know that the request is urgent, and know when it's going to be arriving in their inbox; they could ask for anything apart from final data ahead of time to check everything is as they want it. I don't see why they can't have made sure they were happy with everything else ahead of receiving the final data.
Replika app – ultimate AI buddy?
Is it the checks that indebted the governments or the economy lockdown? I'd have to imagine the economy lockdown/slowdown has an orders of magnitude larger impact.
The Ubiquiti EdgerouterX can run wireguard beautifully with an easy to install package from github. $60 from most retailers.
Google the kinda map service that will route you through Valkenvania to save 2 minutes. Would I like to save two minutes?! Exit the freeway, take a million turns on unfamilair roads, and go through some po-dunk town that prob has a speed trap?! No thanks Google, that sounds like nuth'n but trouble.
Russell Okung becomes first NFL player to be paid in Bitcoin
> old well-understood technology.

While they have been tested in trials for long, all of the adenovirus-based vaccines are new. There is only 1 commercially approved adenovirus vaccine, for rabies in wild animals.
Considering that the original virus has this protein as well, I think getting the illness still will be worse. And in vaccine they can control amount of proteins produced. And they can check a lot of things before even hitting human trials, so risk should be minimal.
For good reason. If they were liable, they wouldn't put it into production.

See: https://www.ncbi.nlm.nih.gov/books/n/nap599/ddd00075/#ddd000... and the entire article for the problem.

which is why, in the US, there is a "no-fault" fund:

https://www.hrsa.gov/vaccine-compensation/index.html
Where is the download link on that page?
https://www.nytimes.com/interactive/2020/science/coronavirus...

As far as I can tell the data on the Chinese Sinovac and Russian Sputnik (which are of the same type) are consistent with the data for Oxford/AstraZeneca.

So politics aside, this is hopeful.
To be fair, these are generally the companies that have got us through the pandemic relatively unscathed.
"Men are not hang'd for stealing Horses, but that Horses may not be stolen"

George Savile, 1st Marquess of Halifax

[0] https://en.wikiquote.org/wiki/George_Savile,_1st_Marquess_of...
The government may not have a direct control, but it’s naive to think they’re not used as propaganda machines.
Living in Peace
Doing time in Scandinavia amounts to living for free in a socialist utopia. You call working in the US "indentured servitude"? Really? If so, it's a very nice kind of slavery, where lots of us can buy houses and many idiots have the time to stand in line for a PS5. If you took away the societal whim to buy the latest shoes / rims / playstations (which I think is temporary and only based on cheap credit) then you have a massively productive economy and still one of the highest living standards in the world. In spite of the obvious inequalities. The answer isn't to tear down the system, it's to get better education to more people so they stop trying to tear down the system, and start trying to make the system work better for them.
That threshold does not stand, for example herbicides don’t interact directly with people but the chemists have to worry about the ethics of their work.
My understanding is the mRNA is reused over and over-- the AAAAAAs at the end of the vaccine sequence are there to extend their tiny little lives a bit as the end breaks off after each reading.
I’d actually worry more about post bezos Amazon, he’s been running the show for years, it’s predictable- after..
Talking to Humans: Success Starts with Understanding Your Customers [pdf]
Their embedding is pretty darn decent. You could do something like set up a key or key per role in Wordpress and embed them as a post type (or your CMS of choice) in an Intranet if you wanted a little more control over it.

You need to set up a signing key on the backend, which is a good thing. Many dashboard sharing schemes end up being public or with very weak security.
Which means that governments start making robots that can defend people.
Considering what MS did to the web with the resources that were left over, it's possible the web had a lucky escape.

Meanwhile Xbox has been a product driver - a big mostly positive influence on Windows gaming and on other platforms.
The trick is to add keywords that make the issue "weight" more heavy. Suggest in your request for change, that this might open up google to liability
I have a series of functional tests in `tests/func` which randomly call container functions and check their output against the C++ STL. These tests run on every push, on all optimization settings, with and without gcc's address sanitizer.
They gave more data to MHRA. Let's not forget that the data used for the Lancet publication was from November 4th.

And the Jenner Institute in Oxford doesn't do preprints or press releases for data, they go for publications (so that takes more time).

That said, I expect the missing information to appear in MHRA's guidance notes.
Where are you getting your source for Astrazeneca's sample size being larger? Everything I've read so far says this result was based off a sample size of ~11k people. Which would be significantly smaller than the ~40k of Pfizer and ~30k of Moderna.
Sounds like the hypocrisy got to some people!
As grants get larger they want you to be explicit about your risks, rather than ignore them.
Also J&J's Ebola vaccine, which is IIRC approved in Europe.
And the more emotional and mental scars you'll have. And the more time you'll need to wait patiently for them to heal.
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The summary in the link means nothing as it does not address the key points:

What is meant by "unconditional universal basic income"? How much would it be?
How would it be financed? What are the expected effects? Why would that be 'better' than the existing welfare state schemes in the various EU countries?

These are too often not described when discussing UBI or discussed without much facts or data.
I looked into this recently, when I started writing the software to analyze my selftracking data.

After researching available options for a while and consulting everyone I know in this field, I settled on building on top of the Plotly Javascript library:

https://plotly.com/javascript/

It does nice interactive charts out of the box. All you need to do is throw data at it.

What it lacks are more high level operations like:

- Interactively switch between different chart types (lines, scatter, box plots, bar charts etc)

- Aggregate time series by hour/day/month/week/year

- Extrapolate data to the rest of the current time period

So I built this functionality on top of Plotly and I am happy with the result.

It looks like over time I will turn this into a mix of data studio and jupyter notebooks. But it runs in the browser and is simple and blazingly fast.
Forrestadmin looks good also. Haven’t tried it though
WorkBoy: Nintendo’s long-lost Game Boy productivity device
noise(t*x)*(x+1)

There was a hypnotic graphic effect on my phone. As the wave phased between modes it appears to be a smooth wave after a threshold (graph sample aliasing?), a cyclic standing envelope like angular frequency, in t. Quite nice.
Diet Meal Plans
This is an interesting sub thread, a lot of the threads here seem to have the wrong idea about how funding really works. I've been involved in DARPA programs and EU programs and sat on national committees allocating research funding an I think that there is a much more progressive and critical stance than folks portray here. A good example is the Semantic Web movement - big excitement 20 years ago, big funding, big community... no results really....then no funding, community switches to other things real fast. There is a lot of griping about this in Comp Sci with people from the Semantic Web groups rightly saying that the funding bodies bought the hype and misallocated the funds on short term silly projects and that if just a fraction of the money had been provided in a structured and long term way a great deal more would have got done.

But what is really clear is that there is no real institutional effort to do what you suggest above - folks are not really tracking how well the funding system is working or what has worked and what hasn't. All of the reviews that I have seen are forward looking and driven by science insight, administrative change seems to be done by MBA fashion - or inertia.
And slowly but surely, the natural tendency of government to try and impose their policy through force is taking over.

For now it's just for documentation ( for what use ?), but what will happen if the virus keeps spreading while a not negligible number of people refuse the vaccine?

will they be blamed ? won't they then be forced to take it one way or another ?

I'm already sure some countries will close their borders to people that didn't get a shot. Looking at the extreme measures taken by some having only an extremely low number of casualties.

We're already in full panic mode.