skysight-inc/HackerNews huggingface dataset:
What?

> adjuvent [sic] is not neccesary[sic] for immune response,

Completely false. Unless the immune system has been exposed to something similar before (e.g. SARS/MERS n.b. made up example I have no idea if the spikes of SARS or MERS are molecularly similar enough), no adjuvant means situation normal for the immune system. If there is nothing to signal to the immune system that this new antigen is bad then it will treat it as neutral suppressing any vaccine response, which is worse that if the vaccine had not been delivered at all.

>is nessecary[sic] for spreading out the antigen producing character among more doses

the point of booster shots is to ensure that antibodies are maintained at sufficient levels to fight off a real infection. If a response has been established, i guess adjuvants are not as necessary? (did biomed, but not a vaccine researcher) I have no idea if they are included or not for boosters.

> rather than using a concentration of mRNA that in itself produces enough protien[sic] to induce immune response

A high concentration won't do shit if the immune system doesn't have anything to activate it, it will just see a high concentration of irrelevant new, i.e. foreign protein.
https://www.theguardian.com/technology/2016/aug/09/facebook-...

There is an ongoing arms race between Ad blockers and facebook engineers.

On mobile, of course, theres no way to block ads
addendum >>there is a halflife/turnover rate, in tech terms the hardware is updated very frequently, by degradation, and replacement. this is loosely what creates a constituatively expressed proteome. the S protien is not part of the program so is degraded and not replaced. if the protien insertion is too extensive or the activity of the protien is egregious for the cell then, apoptosis
The more we move away from judging people as making 'irrational' choices the better.
Anyone have any recommendations on a "modern" digital trunking scanner? (handheld)

I have an old GRE PSR-500 which isn't terrible, but I'm looking to replace it as it has next to zero software support for programming it and doing it by hand is a real pain.

You'd think in this day and age someone would make a scanner with a companion app connected to Radio Reference for programming. Would be nice to have bluetooth audio too.

FWIW, GRE stopped making scanners in 2012, and later closed down and sold off their scanner business to Whistler. Supposedly Whister were going to release a new scanner, the TRX-100, but cancelled it. Seems like handheld scanner technology is still stuck in the '80s.
I don’t think I understand. Are you basically saying that all Republicans literally want to kill you?
> I’d prefer she didn’t end up on onlyfans

You must hate women empowerment and be sexist. You must actively support such wishes to be politically correct.
Now, not only does someone not need to be actively listening, they don't even need to save the audio. Just convert it to text, keep it indexed and whatever three letter agency is doing the tapping has an easily searchable record of your communications should they ever feel the need to look into you without you knowing.
Batteries and screens to come next?

It would be interesting if one of the most well-monied hardware companies in the world would turn effectively independent of key part suppliers (which inevitably target a wider market), and thus of competitors using the same key parts.
Thanks! I saw this over a week later.
What a life!
The flipped cars all lined up next to each other on their sides is impressive work!
The article did compare loading with index vs index after load.

What good do partitions do? Loading in parallel?
> Democracy is the history of choosing the least bad.

Ok, so bothsidesism is justified since you acknowledge both sides are bad?

> If you consider all bads to be the same, you are not a responsible voter.

It’s a strawman to claim both sides are exactly the same level of bad. That’s not what GP was saying.
I didn't say that it's objective or that there is a single "correct" interpretation of every law.
There was a company selling Microsoft software/licenses purchased with stolen credit cards advertising on Facebook that showed up in my feed. I reported the ad to Facebook and they declined to take any action to remove them. They continued for months selling credentials to Office365, etc. that were obviously fraudulent, and for some reason I frequently saw their ads. I ended up reporting them to Microsoft because I’m not a huge fan of fraudsters and wanted to see them brought to some sort of justice. Anyway, they eventually went offline, but I don’t know if it was any thanks to me or if their scam had simply run its course. They were never blocked or removed from Facebook. They just stopped buying ads and took down their website.

It took me less than a minute to figure out this company was fraudulent, but Facebook couldn’t do so even with a tip. It’s pretty clear that they either DGAF or are actively accommodating criminals as long as they buy ads.
I think it's because cyberpunk is generally just a few major technological breakthroughs and <200 years away. People are finding beauty in a dystopian-yet-all-too-relatable world.
The vaccine in this instance is all about delivering a target to the immune system's sentries. If those sentries are defective, or if the hitmen the sentries need to alert are defective, there's nothing this vaccine can do to change that.

"Immune compromise" is generally used as a blanket term, but in many people there are specific immune deficiencies, which may or may not factor into the pathway being targeted here. For instance, natalizumab screws with immune cells' translocation across membranes, and shouldn't play a role in responding to a vaccine (I mean, if it wasn't off the market anyway).

If it's a general immune dysfunction (cancer, diabetes), they will see some benefit, but it will be much reduced - specifically because both responding to the vaccine, and responding to the virus post-vaccination, require the activity of the immune system. What this means precisely will vary with the degree and nature of the immune dysfunction: some folks might see some antibody response, and benefit from repeat dosing. Others might fail to seroconvert altogether, in which case it is what it is.
Learning some kind of common shell language is certainly a knowledge that will serve you well in the widest amount of circumstances. From managing headless servers, to local use on a workstation, to scripting within your U-Boot bootloader, to reverse engineering Linux based IoT/devices that oftentimes include busybox. Shell is included in a lot of places.
Texas is also a right-to-work state, which actually means that workers have no protection from being fired at any time for any reason.

I’m sure that both billionaires will be real happy with that situation.
If I'm recalling it correctly, he said something about it being legal search based on probable cause, and that the cops aren't liable for damage done during a search.

I doubt this ruling will change anything, because his rights weren't violated according to the law. I shared it because cops can do a lot of damage based off of a hunch, and there isn't much you can do about it if they don't blatantly violate your rights while doing so.
No. My view is probably he didn't read any of those papers. He has to know most of his audience won't. He has to know the search results could change too. So he was just sneering at the words.

Changing the search terms is just more evidence he wasn't pointing to any particular research.
Actually there is still Springdale Linux and soon to be Rocky Linux, from a CentOS founder.
that would be the Uniden SD100. I've got the SD200 which is the "console" model.
To really see how these algorithms perform, you should compare the worst case for the algorithm. In order to see if a picture is identical, you’d have to loop through every single pixel, which is the worst case. But you can shortcut on the first pixel which is different, which I imagine happens pretty quickly on many generic pictures. So testing performance with two different images is probably not best for comparison.
They're brilliant at finding this stuff, sure, but incompetent when it comes to business acumen and valuing their work. Usually. Those that have some semblance of the latter, have received in the six figures from singular bounties. I haven't yet read this, and to be fair, most bug reports identify low severity issues which obviously don't deserve a six figure payout.
E-Ink Monitors: Ready for Prime Time? (2020 Update)
Link with the photographer and the can...

https://petapixel.com/2020/12/11/shot-with-a-beer-can-this-i...
Hello dang, please show me at least one plagiarized case, I suppose you are wrong, and I can surely explain it.

Max.
I wear a mask when I'm out and about even if there's no one close. I can't know whether I will pass someone soon and donning a mask takes time. Often it's been useless, as I've not come too close to anyone.

I guess that makes me non-science educated?
Yes. lol.

I worked for a chopper factory in the UK back in the day. We had Novell servers. NetWare CAs back then did as they were told and would only offer rubbish encryption. We used it for throwaway stuff and manually cranked out certs with OpenSSL for important stuff. We also watched firewall logs ...
Then don't buy it.
Looking to try this out shortly. Hopeful:
https://github.com/ParamagicDev/snowpacker
Maybe they're arguing that addition of other parts tipped it from 80% complete to something like 95% complete?

I guess it depends on the wording of the law that allows for 80% kits.
Frame time for this demo is probably near Planck time. I doubt the Atari 800 was getting anywhere near that.
"What's that?"

- Your parents
Considering the source material is a file, that needs to be loaded up by the CPU first, and the operation itself is dead simple, the real constraint is RAM bandwidth.

I would guess that the time of getting the data out to the GPU and back, is about the same as just calculating the difference on the CPU.

So, the quickest solution is probably to use the CPUs vector operations, and read ahead into the registers so you can exhaust the memory bandwidth fully.
DIY Heat Recovery Ventilation
Impulse was sold off to Rhythm Horizon and Reflex I think is the spiritual successor to what Impulse was, by the same people.
> some of the only fans users makes in a month what a plain SE would make in a year.

Sure, of course some software engineers make in a month far more than a plain onlyFans user would make in a year.
This comment breaks this site guideline egregiously:

"Please respond to the strongest plausible interpretation of what someone says, not a weaker one that's easier to criticize. Assume good faith."

https://news.ycombinator.com/newsguidelines.html

How anyone can claim to read someone else's mind like you do here is beyond me, or even claim to know what was taught in someone's undergrad 30+ years ago or how he reacted to it at the time. If I know pg, he would have reacted exactly the same way as now—but more likely he just avoided taking such courses in the first place.

Making these obviously bogus claims so you can attack someone else for, of all things, dishonesty, is pretty shocking even for this thread. I'm not saying that out of disrespect for philosophy, or postmodernism for that matter [1]. What you wrote is just such a breach of basic fairness and exactly what that site guideline asks to avoid.

[1] https://hn.algolia.com/?dateRange=all&page=0&prefix=true&que...
You could write your own shell.
Automated testing of a rendering engine.
Is it only me who found the title misleading? I thought it was a record for can-exposed photos only.
These pads are considered about on par with Cobalt Flux: https://www.maty-taneczne.pl/

I've never used one myself, just going off what the internet says about them. There are lots of reviews of them on YouTube (people either call them "l-tek" or "polish pads")
I like that this doesn't require loading JavaScript to view the static data and visualization. Pretty cool!
That’s the business
> In what sense do you need RDRAND to scale?

Personally? Not at all, I do it for fun. On windows it's all you have because adding anything to the entropy pool BCryptGenRandom draws from is a no go, it was possible ten years ago, a simpler time. Now you have to do it yourself and xor different sources at the application layer if so concerned. On Linux it's trivial.

Cloudflare? Well, besides their obvious immediate needs, they are openly positioning themselves as an entropy provider for high security purposes, which requires good sources and throughput. What Intel or AMD is offering out of the box is not going to cut it by itself.

Not saying they're broken, they work fine for nearly all purposes, instead here positing that if your entire existence and everything you owned depended on it would you truly just use the inbuilt CPU RNG on your computer and call it day? It's a small amount of time to add additional sources and not lose your shirt/dignity.

https://www.cloudflare.com/en-gb/leagueofentropy/
Migos Got into a Big Quarell Concerning Trust
If users are pissed off about Facebook profiting off of them they should have just bought Facebook stock and reaped their share of the profits. Don’t follow Facebook ads.
>> Completely false. Unless the immune system has been exposed to something similar before (e.g. SARS/MERS n.b. made up example I have no idea if the spikes of SARS or MERS are molecularly similar enough), no adjuvant means situation normal for the immune system. If there is nothing to signal to the immune system that this new antigen is bad then it will treat it as neutral suppressing any vaccine response, which is worse that if the vaccine had not been delivered at all. <<

This is Completely false.

Natural immunity does not require adjuvent.

spreading out a scarce valuable resource by use of adjuvent is a standard practice.

ANY complex not recognized by the MHC will elicit an invader response, the immediate vigor of this response is attenuated by inclusion of adjuvent in the final formulation of the vaccine. we would all die 100% of the time if adjuvent was required to mount immune response, to infection.
It's a problem that will be solved better and better as technology improves. GPT-3 is holding a lot of promise in taking input from one domain (language) and generating an outcome in a different domain (commands).

Not sure how bad/good Alexa is, but everyone (myself included) in my household are talking to Google and Siri all the time to do tasks that would have taken multiple clicks on a screen, and a bunch of typing. A huge reduction in friction. The state of the art isn't perfect, but as it improves, it's undoubtedly taking UX in a direction that is popular and desirable to consumers.
I've owned a Cobalt Flux, Blueshark and two Impact Arcades on top of a host of soft pads. It's a sad state seeing the current offerings of pads. Basically the only company manufactured pad is Stepmania X with long wait lists and limited supply or very DIY solutions like the L-Tek pads or used stuff.

I want to start playing again but I literally can't get any decent pad in Europe, which makes me sad. Almost easier to just buy an older cabinet.
The rich will be pulling out all the stops to get their hands on Covid vaccine
You can sell it to others. Zerodium buys 0days for 10 times or more than the original bounties.

https://zerodium.com/program.html
Just read the BFG to my 5 year old. Great book. Reading The Twits now.
The article mentions the Oki 900. Here's a Wired article mentioning how hackable it really was: https://archive.is/AEq0B
And yet they still do it daily. This is why secure-by-default should always be the norm.
What generation of GPU would you need to get any significant & supported benefit out of this, when completed? The discussion about the fallback seems to imply that some pretty rare feature is going to be used at least for some rendering paths. I'm a bit worried that this is then reserved for some current- or previous-gen GPUs, but if you're not amongst the lucky few, you're going to skip straight to CPU.

And if that fallback isn't fast/easy/ubiquitous enough, a widget library using this, might have a different/legacy renderer altogether, with all the chaos this entails.
It looks like you could use some turbocharged WordPress hosting, hit me up if you want a fast website that can handle HN. ;-)
Teams doesn’t even have the ability to reply-quote to a message in chat. Moreover it’s very wasteful with screen real estate.

I’d also add that since my company moved to 365, about once every two weeks I get some email from it dept talking about service level disruptions.

And in the meantime it emails it’s creepy “we were watching your productivity” messages weekly.

Not a fan.
Have you heard of Complexity Explorer? https://www.complexityexplorer.org

I've taken some courses and they're really quite intense. The bonus is that they are free (subsidized by Santa Fe Institute). It's definitely a niche audience, but what they are teaching is very current.

I occasionally see links to some of the instructors' other works here on HN, so it is probably a good fit.

Also, there is Lynda.com. Where I live, you get free access to Lynda courses with your library card. Pretty amazing deal. I don't know how wide spread that is, though. I've taken some of their coding courses years ago and they were pretty good. They're constantly updated, so sometimes the search function is a bit hairy though.
I think some embedded medical device software developers might have a dog in the hunt.
I’m sure he has his source. Did he cite his opinion as a journalist or a blogger?
Which packages had a hard systemd/logind requirement upstream? As far as I understand it, GNOME still gets upstream patches from BSD developers and is still supported there. (Some Debian packages do have hard dependencies on systemd, but this is a downstream packaging issue)
This is a quote from the article:

> “While an engineering graduate was promised Rs 21,000 per month, his/her salary had reduced to Rs 16,000 and, subsequently, to Rs 12,000 in the recent months. Non-engineering graduates monthly salary had reduced to Rs 8,000. The salary amount being credited to our accounts have been reducing and it was frustrating to see this,” an employee alleged.

Not being familiar with Indian pay practices, just wondering what the company thought the outcome would be after trying this? That nobody would notice?? That they'd just think "oh well, that's OK, company must be short this week"?? Because pretty much in any sizable American company employees would just stop working if they didn't get paid.
“topsy-turvy” sounds funny. I had never heard it.
Blackmail with a bit of overhead tossed in then. At least most hackers keep the costs down and pass the savings on to you!
This comes up on every thread about vulnerabilities. Zerodium doesn't buy random one-off serverside bugs. It's not that they simply don't have a price listing for them; it's that they don't make a market for them at all.

It's not even cut-and-dried for the RCEs that firms like this do buy. Bounty programs at giant tech companies are generally aware of the market prices for RCEs and are not overtly trying to screw you over. The flip side is that the price you get from a broker is (1) negotiated and (2) tranched, so the "number" you get is a best-case, not guaranteed, and can collapse if the bug is burned before the IC agencies the broker sells it to finish using it to hurt people. The bounty number, on the other hand, is a sure thing.

But ~nobody is buying auth bypass vulnerabilities. Maybe if you can mint OG Twitter accounts and aren't worried about going to prison.
I just don't buy games on release. For singleplayer games there's really no reason to not wait a few months for the major bugs to be fixed, or even a year or two to get all the dlc with the game at a discount. I also stick mostly to indie or AA games which don't have this problem nearly as bad to begin with and have new, interesting ideas and mechanics way more often then triple A games that cost twice as much anyway.
You mean, others that are providing real authorized battery replacements from the manufacturer of the original equipment? Ones that should be more likely to be covered by insurance if they do cause a house fire?

Those alternatives?
I once overheard a phone interview for a position so interesting that I wanted to apply for it myself.

The answer to "How did you hear about our company?" would not have gone well. :-)
This isn't anything equivalent to a zero-day in a web browser, for instance. It's trivial for Facebook to patch and it can't fit in a "slot" filled by a previous bug. Note that vulnerabilities in a specific web app like this one are not listed on Zerodium's website.
Not to disagree but I believe that the nature of their government, the social democracy, that empowers people and their needs, built up the trust they have in each other and their representatives.

It's also the reason why they accept very high rates of taxation in exchange for public services that actually work and benefit the population.

Depicting Scandinavia as an uniform land where a genetically homogeneous spawn lives is also misleading.

For example in Denmark 86% of the population is Danish descent, same goes for Norway, in Sweden 18% of the population was born in another country.

In Italy, which is not particularly famous for its genetic uniformity, 90% of the population was born in Italy from Italian parents.

What seems uniform in Europe, except for Scandinavia, is the distrust

European countries shows that average trust in the police tends to be higher than trust in the political and the legal systems. And trust in the political system is particularly low – in fact much lower than interpersonal trust for all countries except Switzerland. On the other hand, trust in the police is notably high, and in the majority of European countries people trust the police more than they trust each other

Italy has the highest level of trust in the Mediterranean area, around 30%, while France, Spain and Greece are below 20%.

Netherlands have the same level of Scandinavia (>60%), Germany is around 50%.

My personal belief is that the society trust is directly proportional to the level of social conflict.

Not surprisingly France, where social conflict is quite high (which I don't think is bad per sé) has the lower level of trust in Europe (~18%), except for Romania.
Does anyone understand why the FDA and other experts seem very unconcerned about long term side effects?

The safety profile in the 0-2 month timeframe is very easy to understand: they tested it, so they have actual data. But it seems for longer than 2 or 3 months you would need to make an argument based on animal trials or just biological reasoning. But I can't find anyone talking about it at all.
Seems like it would be hard to quantify number 2, depending on how your define "harm". Foreign relations might be harmed (which might indirectly lead to deaths down the road), even if nobody was directly killed or injured because of the leak.
Stockholm ICUs at 99% Capacity
One use case I've used them for is when you have a table that is 'under fire', and you need to add bulk data to it. Doing a large insert into a table like that can cause various issues. Instead I a partitioned table and each bulk load is a separate partition. This allows doing the bulk load to a 'clean' table out of the line of fire. You can then apply indexes, do cache warming or whatever else you may want to do to it, then attach the partition to the parent table to make it 'active'. As long as you have covering constraint on the partition that matches the partition constraint, this results is minimal impact to query performance. We do bulk loads of partitions with ~100-200M rows this way and it's barely noticeable to the query side latency.