skysight-inc/HackerNews huggingface dataset:
I see, thanks for the reply!

I was thinking that maybe because Covid is an RNA virus, there would be a shortcut to getting the mRNA sequence for creating the spike protein. The scientists could peek at the RNA in the actual virus, recognize the spike protein, and put that in the vaccine. Whereas with a DNA virus, it would require extra work.

But from your answer, it sounds like that's not what they do? Or, maybe they could do that but it's not any easier than working backwards from the amino acid sequence.

This stuff is all very interesting!
an immune compromised person may require larger repeated doses, or a different/concurrent strategy such as antibody infusion
I have created a Product Hunt for Summon The JSON and invite you to vote on it, thanks: https://www.producthunt.com/posts/summon-the-json-javascript
After reading your post I did the same thing. Similar results 90% to 20% in my case. Anecdotes aren't data but I am glad I tried.
Naval Ravikant is a bit of a "head in the clouds" type, but he does have some genuinely interesting ideas that are worth paying attention to.

The problem with both Ravikant and Graham is that they're pontificating in a space where the ideas seem superficially trite but become powerful when applied.

I think of Dale Carnegie's book 'How to Win Friends and Influence People' as a good illustration of this. People around here especially love to hate on it, but that's because they don't quite understand the point of it. The point of that book (and of the musings of people like Ravikant and Graham) is to explain to people that success is a product of attitude and behavior as much as it is a product of intellect. That simple ideas, routinely applied, can yield wondrous outcomes. And, perhaps most importantly, that the ingredient for success absent in most STEM-inclined minds is the capacity to restrain analytical/cynical impulses in just the right way.

Neither Ravikant nor Graham is an intellectual slouch. They have noteworthy backgrounds in STEM that categorically refute any possible accusation of dimwittedness. When they decide to discuss 'soft' ideas, it's because their experience in the real world, pattern matching against countless observations made in the trenches of the tech industry, has taught them that these ideas are crucial.
Earth mass extinctions of life occur in 27M-year cycles
Battery recycling is moving forward so fast that it makes 2019 feel like ancient history.
Show HN: Cyberpunk city, Urban fantasy art, Rainy city
Zodiac Killer Code Has Been Cracked
Regression testing image processing algorithms.
What does it mean to be a moral philosopher 'by trade'?
What's the point of the firefox version when you can just set dom.event.clipboardevents.enabled to false?
Oh, like parts incompatabilities between say Ford vs BMW vs Toyota when having to find replacements?
Users and supporters do. And they make the money to pay however they usually do.

They may also make money using the software to do whatever it is other people will pay for. That is the case for one project I contribute to on Pateron. Use value is real high and a community of users is funding the developer.

I am supporting a couple of other projects that way right now. I've got good developers on Patreon, and I'm happy to know that they're developing the software that I value. That's the end of it.

I'm also happy to know that software is out there for general use too. I don't really care if everyone's paying. Would I do care about is the developers are getting paid.

I think more developers should communicate where they are at in terms of support, and I think a whole lot more of us need to put small amounts of money toward making sure those developers are okay.
But that's exactly the thing, no one has ever needed a party to tell them who their enemy is. With more parties, there would just be clear coalitions, one conservative and one liberal. To the extent that parties switch allegiance, it will be because different people are members, not because existing members changed their political tribe.
Anyone have suggestions for Firefox?
Yes, that makes sense. I was just wondering if the target virus is already RNA encoded, if that provides any shortcuts. It sounds like maybe not.
And I "literally" provided two examples of where it's a bad choice.

If you are the only person viewing your screen, then by all means use whatever color scheme you like. I never said it was bad for you. I just illustrated when it is bad for some people.
One standard that has stuck out to me is shipping pallets. This piece[0] opened my eyes to how they standardize what a commodity is:

> The magic of these pallets is the magic of abstraction. Take any object you like, pile it onto a pallet, and it becomes, simply, a “unit load”—standardized, cubical, and ideally suited to being scooped up by the tines of a forklift. This allows your Cheerios and your oysters to be whisked through the supply chain with great efficiency; the gains are so impressive, in fact, that many experts consider the pallet to be the most important materials-handling innovation of the twentieth century.

[0]: https://www.cabinetmagazine.org/issues/52/hodes.php

(The piece is far more interesting than the bit I quoted)
The discreteness is a distraction here. You are interested in the total flux of light, from all stars in some patch of the sky. If some of them contribute on average less than one photon, that doesn't matter, it doesn't cause some sudden drop-off in intensity.

If it did, the same thing would happen not just for stars, but for all sorts of things. If you position a computer screen on a hiltop far enough away that, on a dark night, you can just make out whether it's on or off, then your eyes are getting about 6 photons per second. It doesn't matter whether these come from a million separate pixels, or from one light-bulb of similar total brightness.
There are plenty of people who have genuine passion and interest yet don't succeed. Sounds like survivor bias. Funny that you also appeal to authority -- PG cant possibly be wrong because he is rich and successful :).

Also studying society/people is an academic discipline. There is plenty of hard science which is equally "bogus". What about bad neural network papers, or bad physics papers?

Regardless, these things are not new ideas, or something people don't know about. Yes being eager/earnest can help. Yes bad papers exist. The issue is why choose that particular example? Why are all of PG's blog posts exactly the same -- none of them have anything particularly deep or offer new insight -- but there always seems to be controversial content mixed into the supposedly honest discussion.

If they are not doing it deliberately and its somehow internalised then people should at least call them out.
It's a bug in the CSS when the width is too small– increase your window width to fix it– feel free to submit a pull request.
Maybe things have gotten better. I worked for one a while back and came away with a notion of the two distinct communities I described. I try to focus mostly on the positive side, which was the majority and had some amazing and inspiring folks, but the other side had some really irritating people with wholly unprofessional conduct.

Bug Bounty King really spoke to me haha
For people not familiar with the term bps: Basis Points (BPS) are a unit of measurement equal to 1/100th of 1 percent.
BMW used price drop like rock, 2015 328i are about 18k.
That money is coming from men (mostly men) willing to pay it, I think that's what you ought to be upset about if the situation upsets you, although I don't really understand what about it "broke your back".

I think you are hugely overestimating the number of women making any kind of significant money on onlyfans, let alone the kind of "in a month what a software engineer earns in a year" money you're talking about. That's very few people. If that makes you feel better for whatver reason.

Like every other internet hustle (say instagram "influencers"), so many people are hustling and maybe being taken advantage of and making very little. Who does make serious money is some combination of luck, business sense, aptitude, and lots of work. Some women get rich being models too (and this is of course a kind of modeling, or at least that's part of it), but it's not like any woman can just decide to become rich by modeling.

I'm not sure what you're alarmed about, but if you are foreseeing a future where all women choose to pursue no career but onlyfans, which seems to be literally what you are describing being alarmed about, I don't think you have to worry about that, so perhaps you can sleep better.

Also not sure why we're talking about this on a post about Facebook security vulnerability and their bounty program, but ok.
Now that I haven’t heard!
The Chinese are slow at catching up.

Export and trade sanctions and embargoes have a long history as part of US foreign, pre-war and war policy. For example there was an oil embargo imposed on Japan from the US preventing oil from the US AND other countries before Pearl Harbor.

Of course trade embargoes were imposed on the UK by Catholic Europe when the Church of England was established.
Apparently I did not write my post clearly, because I did not think I ever said it should be outlawed. Options are great. I did suggest that people consider their mode choice if they have an audience.
I've never quite understood how the "no fly list" is itself a constitutional process in the first place. It lacks due process and transparency with an appeal process that is administrative rather than judicial. I don't understand how the government can constitutionally invoke a penalty without first having to prove that some violation has occured.
No, but your reference to freedom of expression just scans a little oddly here because no one is claiming this person should be deplatformed or something.
I've built something very similar as well.

For me, I found that the display I'm using works reasonably well for photos, but you need to slightly boost the contrast of the image before updating the display, to compensate for the darkness of the display. If you're using PIL in python, this is just something like "image = PIL.ImageEnhance.Contrast(image).enhance(1.3)"

I do that immediately before dithering into 16-greys, and get entirely acceptable photo displays that way.
How does it make it necessary for developers not to be arsed to do the work for other browsers?
> I call your attention to the fact that felons are 5 to 7 times more likely to vote for democrats than republicans.

Well, that is what happens when one party seeks to remove your ability to vote, and the other defends your ability to vote.

> That just isn't the law-and-order party.

I’m amazed that you can imply that the Republicans are the law and order party, and not realize that you’ll get laughed at. Mad props.
This year I dove deeper into the mechanical keyboard hobby. I bought a 3d printer, learned how to tweak the settings to get decent prints, and then I printed some cases. These were used to build a hand-wired dactyl manuform keyboard.

I've also gotten into woodcarving by making figurines of animals.

Making things is fun and relaxing.

Example of similar keyboard: https://github.com/abstracthat/dactyl-manuform
The one unfortunate thing buried in this story is that it seems this paint is not, in fact, quite as black as Vantablack. :-(

(although it's cheaper, easier to use, safer, and you can get it if you're not Anish Kapoor, so there is that)
The Practice of Change: How I survived being interested in everything

Doctoral dissertation, academic year 2018

Keio University
Graduate School of Media & Governance
Joichi Ito

"How can we understand and effectively intervene in interconnected complex adaptive systems?"

"Joichi "Joi" Ito (伊藤 穰一, Itō Jōichi, born June 19, 1966) is a Japanese entrepreneur and venture capitalist. He is a former director of the MIT Media Lab, former professor of the practice of media arts and sciences at MIT, and a former visiting professor of practice at the Harvard Law School."
Awesome! I was hacking on something similar[1] when I was I grad school, but i never had time to polish it up for public consumption. Maybe you can find some code or ideas of use from it.

[1] https://gitlab.com/tmearnest/pdfs
a) I think most people have realized these types of rules are toothless. You're not going to go around knocking on doors on Thanksgiving (nor would it likely be legal do so). Everywhere I've heard about was strongly urging people not to gather for the holidays outside of your household.

b) Outdoor dining is tricky, and a lot of that is a government created problem. Outdoor dining at truly open tables, properly spaced with good ventilation is probably fairly low risk. At least where I live though, restaurants went out and bought large, fully enclosed tents and filled them with tables to comply with the letter of the law. Unfortunately these don't have very good ventilation on average. The virus also survives longer in cold, dry air so during winter you could logically make the argument that these tented dining situations are perhaps less safe than indoor dining.

As I said, this is a government created problem, since they probably should have given guidance on the best practices for outdoor dining before restaurants went out and spent thousands of dollars on them, but they likely made the political calculation that its easier to just close everything.

There's also the possibility that outdoor dining makes young people from separate households (say 6 twenty year old friends) gather together at one table without masks, but I suspect that if they're doing that at restaurants now they'd just move to someone's home and order pizza when the restaurants closed.
I do so much of this it would be hard to document all of them. In a very large lisp project, I had an astonishing number of lines of shell code--none more than 10 lines long. (Today I would do production automation with cl-readline and inferior-shell and uiop:launch-program.

Also, given that I use emacs, I do lots with dired, and on odd occasions eshell. And I have gathered a bit of emacs lisp code as well.
the short cut is that DNA virus has a further layer of code utilization , the DNA must be read out and transcribed to mRNA, then translated to protien. there is an extra step in there, but you can still use a synthetic mRNA to create a protien specific to putative antigens decorating the surface of the DNA virus, or of the infected cell, or both if your rich and want to make sure.

a DNA virus must be understood somewhat to find the reading frame for the protien you need, this is the case for RNA virus as well however RNA virus are limited in size due to the instability of RNA, this means less kruft to wade through until you find the FOO
CentOS has had a stability advantage by being downstream of RHEL. It makes sense to switch the free version to be upstream of the paid version.

Unexpectedly changing CentOS 8 after many had already migrated to it makes no sense and thoroughly damages Red Hat’s reputation in my view.

Perhaps Red Hat will consider continuing CentOS 8 under the same terms they had promised, while also releasing CentOS Stream. Many would value earlier updates over additional stability and make the switch willingly. The rest would avoid having the rug yanked out from under them without warning. Obviously, this dual path would require more effort, but it would engender more trust in Red Hat going forward even if we knew there would be no CentOS 9. It would also keep many from migrating elsewhere.
It's also all-app: they can change their homemade updater to a normal non-hidden updater and have normal signed distribution that doesn't require any of this re-auth.
Since FB’s stock is structured such that Zuckerberg always has complete control[0], they are not really beholden to “Wall Street” (shareholders). Sure they want the price to go up, but the CEO cannot be removed without his consent. So on some level, they must want these things to happen, either that or they don’t care. (Neither possibility is particularly good, of course.)

[0] https://www.cnbc.com/2018/03/20/shareholders-wont-force-zuck...
To be accurate the internet existed but we didn’t have the web resources,

'Store and Forward' via UUCP was my norm around 1991.

I remember how our little group of UUCP nodes was so excited when one of our members sent an email from Australia to the States. (And received a reply back!! In only 10 minutes!! WOW!!)

I recently just gave away a bunch of my old reference books

I have had many cleanups of my reference books and magazines from the 80s-90s era. From about 50 shelf-feet to about 3 shelf-feet. On the other hand I have also re-bought some of those discarded reference books. And several other books are getting very tattered, but still used after 30-odd years.
> You should have thought about that when you supported weakening election security

It's difficult to take Republicans seriously when they didn't file a constitutional lawsuit against every state who implemented vote-by-mail in response to covid-19, just the four states that would need to be disqualified in order to make Trump the winner.

> Next time, maybe cooperate on election security? Is that too much to ask?

Sure, no problem. Fund the FEC and make it their mandate to find every eligible citizen and issue them a free election ID card. If your answer continues to be 'make it a state ID, and by the way we will make it so DMV is only open one day every two weeks for a couple hours in this black neighborhood over here' then it just looks like continued attempts at voter suppression.

You can't try to pretend you are acting in good faith when it is so obvious you aren't.
There was the... I'm going to call it the no-hugs-coc drama a few years ago (https://www.theregister.com/2018/02/21/freebsd_code_of_condu...). Not exactly earth-shattering, but I think that counts as drama.
Presumably that they're an academic moral philosopher.
I don't pack a desk in my messenger bag: a laptop, pencil, and notebook suffice.
I'm just stating how things are, not trying to convince you to play GW2.
One thing that I don’t understand is what happens to the cells in which the mRNA enters. Do they die? Do they go haywire? How are the spike proteins getting out of them? And if the cells die, how many of them are going to be affected by one shot?
A Narrowing of AI Research? With Juan Mateos-Garcia
I can assure you that if you produce dark mode content, people will not be able to view it if they are sitting outside in typical daylight.

I know this because I have tried, with three different modern laptops (two MBPs and an XPS) which have the best brightness available for laptops. If I hit dark mode content, it just has to wait until I'm indoors. But usually I'm looking for something because I need it at that moment. If I can't view on potential illustrated video, I will try the next one I can view.

People taking the time to produce content often do care about attracting and keeping viewers/subscribers, and this is a case where an accessibility issue will reduce the number of viewers.

I highly appreciate the effort people put into sharing their knowledge, but I find it really disappointing when I can tell that their effort is wasted on some potential viewers. I may be weird (no, I am, but that's not necessarily a negative), but I know I'm not the only person with this opinion.
I clicked around the site and skimmed a few articles but I can’t figure out what exactly “Risk-first” development entails.
I really enjoyed the depth and detail this article went into to make its point.
IANAL, but it definitely sounds like he's painting a target on himself for civil damages if someone else hacks you by using an exploit he shared.
Is IntelliJ IDEA not modern enough?
You literally said the people on the right vote against their own self interest, now you’re saying that they vote against change you want... but isn’t necessarily better for them. If you’re wondering why ppl don’t take you seriously this is why.
Indeed. That would’ve been nice. It may even be there, but there was so much other junk on the page that I could barely tell what was the article and what was an ad on a mobile device.
I don't understand why Paul Graham puts himself out there in the public sphere like this. To read all the haters and cynicism here that he gets in response - a lesser man like myself would just say screw it and walk away.

Like his critics here are terribly accomplished people. Paul Graham is a expert with a proven track record and some multiple of billions of "market votes" behind him. But the armchair critics on HN know better. I expect that on YouTube comments, I have higher expectations here.

Whatever his motivations, I enjoy his essays and find them thought provoking. I just hope the peanut gallery here and elsewhere doesn't discourage him.
What do you mean by remedying at a lower level? Don’t plenty of states and counties also have split polities?
So, what is your proposed solution for people who find security vulnerabilities in systems?
Keep in mind these vulns are worth money in the black market.
There's negative incentive for the selling company to do this. Too much of a risk that your prospective customer's engineers are just there for inspiration.

This is why pilots exist.
You must have missed the FreeBSD code of conduct change 2 years ago and all of the port maintainers who left as a result. I’m not even a FreeBSD user but heard about it.

hug
This looks like a deep dive into the software development portion of the Riskiest Assumption Test. The RAT has gained popularity in recent years over the Lean MVP.

The RAT is really important in areas like Healthcare that require a lot of monetary investment to build an MVP. In my experience, the hardest part about the RAT from the technical side is convincing people before building that their MVP assumptions or technical understanding may be wrong. Technical RAT only works if estimates are trusted and management isn't overriding technical judgement.

Whether it's RAT or MVP, the most important priorities are still talking to users and working from solid data, to avoid leaning on assumptions.
Funny, I actually learned Linux the opposite way. I started using Gentoo. I know that seems like learning Linux on hard mode, but for me it worked well. I had dabbled a bit before that, but I didn't really get Linux, before getting my hands dirty in this way.
Finder’s fee
Lol. I love when someone like you comments this without any irony. You truly believe this nonsense like it’s gospel.
> Cutting 8 years(I think? have something like 2029 in the back of my head)

Correct: https://web.archive.org/web/20201101131417/https://wiki.cent...
Well, considering CPL is the origin of C, and that developing CPL was indeed « a damn stupid thing to do », it is fair to say the title has something to do with C.
Don’t get me wrong, it is clickbait anyway.
Actually they are really cute flashcards and its not a convoluted way to remember this information but actually it applies active recall to python.

https://en.wikipedia.org/wiki/Flashcard
I don't need to have a working exploit for Firefox to accurately state that it's easier to exploit Firefox than it is Chrome.

I encourage you to read writeups on the patched bugs for Chrome sometime.
Diff testing UIs.
employed (by a university) as a moral philosopher. Interestingly the institute they work for is ethically dubuous (because of how it's funded, not the teaching content)
Using an "if" doesn't mean coercion if first action is legitimate

- I'm going to refuse your offer if you don't propose something better.

- I'm going to work on it if you don't want to

- I'm going to eat the cake if don't like it
Interesting accusation. What attributes of this photo would lend itself to be of better quality in such a display?