skysight-inc/HackerNews huggingface dataset:
There are two threads here. The first is that it would not be surprising to learn that describing the way that proteins fold is a very hard thing for humans to understand. See i.e. 4CT [1] and its computational proofs.

The second is that explainability in ML is much more tractable than it was 10 years ago. This is not to say that it's solved, but having solved the predictive problem -- I would expect model simplifications and SME research to proceed more quickly towards understanding the how now. I did some work w/ an Astrophysics postdoc using beta-VAEs [2] to classify astronomical observations, and simplifying models in order to achieve human-explainability proved to not cost as much predictive power as you might expect. It might be that the same holds true here.

1- https://mathworld.wolfram.com/Four-ColorTheorem.html

2 - https://paperswithcode.com/method/beta-vae
Romoss LT20 Pro 20000mAh Power Bank
Maybe like me, they grew up in a country where mathematics itself is pronounced "mathematica" (which is a huge fraction of languages [0]), leading to avoiding that name for the software.

[0] https://www.indifferentlanguages.com/words/mathematics
That would probably be caught by the CI, though, wouldn't it? One of the packages would fail to install in a clean venv and the tests would fail.
Complex Numbers, Math.atan2, and Phase Unwrapping
No offense, but if some code/library/project has no proper README and documentation, I immediately dismiss it as a potential candidate for use in any of my projects.

It is unclear to me what this even is and why I possibly should want to use it.
You've got to balance the risk from the vaccine against the risk from covid. The first is probably vastly less even if non zero.
Looking at the Lunatic readme: https://github.com/lunatic-lang/lunatic#architecture

"Lunatic treats WebAssembly instances as actors. Using WebAssembly in this context allows us to have per actor sandboxing and removes some of the most common drawbacks in other actor implementations."
No, because instead of worrying about the bad data, the powers that be will instead take the bad data as-is. No one cares about data quality, they only care that they have someone or something to point to when they make terrible policy decisions. THAT'S the problem.

Why do you think Trump wants to exclude illegal immigrants from the Census? The media will never footnote data because they are lazy or don't understand or they've given up.

The same goes for when GW Bush took the cost of the Iraq War out of the budget. Every media outlet just fell in line and reported the budget as-is, instead of saying "Oh by the way, the trillions of dollars spent on the Iraq War aren't part of this number."
Public may need immunity passport for ‘restaurants, bars, and cinemas’, minister
Ask HN: Leaving at Big Tech: Is two weeks too long?
Hey HN, I've been an obedient employee over my career but will now be taking a new role at an exciting company.

I'd like to start ASAP but of course two week's notice is the standard. Every time I've ever given a two week's notice it's been a slog of a two weeks - usually at these bigger companies there are plenty of folks to kill the gap and there are rarely "single points of failure".

I'm planning on giving a one week's notice today and I feel it's a very fair amount of time. Am I wrong?
Its not incompetence, its corruption
It counts as experience but only if it is relevant to the position you're applying to, also the optics of your project matter a lot (does it look cool or does it look like a mess).
I don't have any skin in this game, I'm just sharing my thoughts. Besides, in Europe they're limited to 30 minutes of recording (otherwise they're classed and taxed differently iirc).

The laptop thing - using a bigger heatsink, or more copper, or better thermal paste, or multiple heatpipes instead of one (that was actually HP's solution to their overheating ZBooks) would cost pennies and would actually keep the CPU/GPU under throttling limits.

I've repasted and modified enough laptop heatsinks to know it's a very easy thing to do. But the manufacturers don't care. I get it, a dollar saved on one machine is a lot of money overall. I'd rather have it cost $10 more but have a decent heatsink.
Anyone who loses their money when an exchange collapses has not lost bitcoin, they already spent that bitcoin on a bitcoin-denominated-receivable and then lost that receivable.
A bunch of video games do this ('shadow banning / shadow pooling') - with varying degrees of success. A lot of the cheaters still just create new accounts every so often.
It used a lot when systems are examined at the nano-scale. Metrification and creating a "fubini's theorem" for a specific problem to measure something (indeed category theory is useful for building a localized "global wire" with appropriate "gauges" of interesting where optimization methods will work (to achieve the non-equilibrium control-theoretic orient-folds of interesting of whatever "the soln" is) with enough "space" to "try" pull-backs and push-forwards as needed (for a class/family of physically analogous of data). I thinking looking at things trough Joseph Fourier's eyes is pretty englightening. He sees to have ideated both the heat transfer problem (and being able to apply modern methodology by forming distributed or sparse representations of it, then assessing the non-linear dynamics of it modern robotics and mathematics senses to it, which would be very much applying pfaffian dynamics to me, and being able to know about cohomogies is a blessing such that the appropriate physical effect where the maximum likelihood is constained). is important in both scale free systems, fibers of networks of systems that need to be localized (this is approximately global sections of global optimization but then model indentified), mass effect which require some sort of techno-economic analysis (think the climate resilience problem) and (historically, I think COVID will shift that) lack of progress towards applied coding in the life sciences vs information sciences. What's pretty surreal to me is that exploring (and documenting some of interesting blurs between fields), say like math, physics, statistics, computer sciences, signal processing, natural language (even of language of scientific discourse), renormalization methods, naturalizations, socializations, and what are global/local laws lets you almost do a approach it as a "reverse Robin Hood" problem.
I know that acting lessons often have enunciation training. That's partially why there is a "TV accent" that's more or less regarded as the standard US accent.

As a non-native English speaker, I've found that the best way to make myself understandable is to enunciate the consonance clearly. It sounds weird sometimes, and clearly not native, but it's always clear.

Another thing I've trained myself to do is the control of rhythm and stresses. I got this idea from a book on poetry, which classified English as a stress-timed language. Coming from a mother tone of Chinese, I'm not used to grouping rhythm centered on stress syllables. For me, stresses used to live just within an English word, as notated by the dictionary.

When I started to pay attention to a sentence-level flow of stresses, I finally understand how English speaking people gloss over some syllables and emphasize on others. I've even noticed that many eloquent speakers naturally slip into a iambic pentameter when they talk.
> Antisense drugs are much simpler, with no immune response required. The mRNA (the drug) itself simply binds to the target mRNA.

Does that make them a class of "cures" rather than "immunizations"? If I get infected with the same thing a year later, will I need another dose of the antisense drug?
Speculation: Scented Candle Ratings Down Due to Covid-19 Loss of Smell
I am also wondering. I generally find these kind of approaches hard to believe, but this might be my prejudices.
The thing is: Not everything with a large, technical name is bad. Simply having preservatives isn't necessarily bad - and neither is artificial flavorings. I'm pretty sure modern "Beef sticks" aren't really bad either - I'm gonna guess you mean something like a "slim jim", whose ingredients seem pretty standard [1]. They just aren't good if you live off of them as a standard part of your diet.

And honestly, if you don't differentiate that you don't mean that stuff, there is no way for a reader to tell. Some people absolutely mean processed foods like smoked fish, canned/frozen vegetables, and the like.

[1] https://www.amazon.com/Slim-Jim-Smoked-Original-24-Count/dp/....

Edited for spelling.
> Running a pip freeze to generate a requirements.txt file doesn't work nicely when you use a requirements.txt file to define your top level dependencies.

Use setup.cfg to define your top level dependencies. Use requirements.txt as your "lock" file. But even then you won't get reproducible builds across different OSes, or with different non-Python things installed on your machines. Use Docker images to guarantee staging and production will be identical.
Cadillac shipped DSRC in the CTS sedan: https://media.cadillac.com/media/us/en/cadillac/news.detail....

Volkswagen is shipping DSRC in their latest Golf: https://www.cnet.com/roadshow/news/volkswagen-new-golf-cars-...
Pepsi and Coke don't have an install base either, as they are 1-day consumables.
I found https://github.com/nathanj/predator-epub which worked pretty well.
Or to put another way, the kings and queens of yesteryear funded a staggering amount of beautiful art, etc.
WIPO reaches 50k UDRP cases since 1999 and has an 11% increase in 2020
lol that’s what happens when technology increases productivity. I actually addressed all this. Staples will continue to be purchased hand to mouth leaving the poor unable to benefit from deflation while the rich sit on their idle cash and grow their largesse without increasing economic activity.
Doesn't it depends on the application ? i.e. some applications can tolerate false positives/negatives ?
I think the second half of your comment is sarcastic but also... entirely correct?
Processors are complex. Architectures are over my head. Is there an intelligent layman's video or article series not just on architectures, but how, at a high level, ARM is supposedly so much better than x86 in the long term?
They do help indirectly - by innoculating the 90% who can take a vaccine, the 10% who can't (for example babies when it comes to measles vaccines) are unlikely to actually catch the disease.
Nearly one-third of NY, NJ small businesses reportedly closed in 2020
There is one! Pip supports, since a few years back, a constraints file (i.e. a lock file) that does just this.

This is a nice guide on how to use it: https://www.lutro.me/posts/better-pip-dependency-management
I listed as opinion, but it is actually a fact. It's a phenomenon across sports. Including wrestlers who do long drawn out sessions, losing strength and mass as a result of their training.
Yeah and anybody who loses their money on the stock exchange, already spent that money on a security and then the security lost value. What's the difference?
You seem to have missed that the point was that they denied benefits to US citizens, merely because someone else in the household did not have a SSN.

But regarding actual illegal immigrants, it's amazing how many people complain about "giving" benefits to immigrants while apparently being completely unaware (or conveniently forgetting) that a significant fraction (perhaps even a majority) of those immigrants actually pay taxes.
Overtake is when you go past something. Apple is moving faster than anybody else but hasn't caught up yet.
You joke, but this was more or less the default behavior we expected from average new hires on remote teams before COVID. I referred to it as the "college schedule" because a lot of new grads just continued their college procrastination habits right into remote work. People treated it like a group project where they know someone else will care enough about their grade to make sure the project succeeds.

It doesn't take long before the high performers on those teams get sick of picking up the slack. The high performers move on to companies that care, while the team's output continues to decline as everyone pushes the boundaries of how little work they can get away with. Eventually management wonders why certain teams have so many people but so little output, "restructuring" occurs to trim the slackers, and the hiring cycle starts again to build the teams back up.

Performance management is more important than ever when leading remote teams.
Ask HN: Why doesn't the U.S. gov't just shut down Wikileaks.org?
If it's such a threat to nat'l security, why don't they just shut it down like they do for all the piracy sites?

I was reading https://greenwald.substack.com/p/a-long-forgotten-cia-document-from which prompted this thought

>To the list of the enemies threatening the security of the United States, the Pentagon has added WikiLeaks.org, a tiny online source of information and documents that governments and corporations around the world would prefer to keep secret.
but python has been around for a while, I feel the frustration comes from the fact that other platforms seem to have managed to get a single working tool much earlier.
Alot of those puzzles are damn hard, ELO ratings there are legitimate.

I feel that chess Tempo has really given me tools to recognize recurring tactical motifs in actual play.
Maybe it is better, but I will never ever install anything via

curl -sSL https://raw.githubusercontent.com/python-poetry/poetry/master/get-poetry.py | python -

call me security paranoid, but

curl | interpreter

is not an installation method.
https://archive.vn/hmqsC
Probably a lot. I wonder if we could have some sort of algorithm, or maybe machine learning to maximize human wellbeing for the next pandemic.
Such a great idea! Great quality of service that everyone actually need for efficient workflow. Highly recommend to check and test it.
Good comprehensive article, but the headline is somewhat misleading. If I read the story right, Pad 4 at Vandenberg hasn't been used since 2019. In the scheme of space launches, that's not such a long time.
I'd say people in other places have it way easier. They don't fear bankruptcy when considering whether or not to get a health checkup. They don't pay the majority of their wage to have a decent livingspace. They pay less for food and overall have less cost of living. Poor people in the third world can eat decent meals (and they don't even need to cook it themselves) for almost nothing compared to the US. What do our poor have access to? I guess dollar menus at fast food chains.

So no, I don't think it's fair to say people in the US have it easy. You have it easy, and maybe the people around you do. But that means nothing to all the other people whose pain and suffering are invalidated by people like you just because they happened to be born on a piece of land that happens to be classified as "first world."
Diverging Color Maps for Scientific Visualization [pdf]
After multiple decades without so much as a kiss, I think "luck" as a factor can be moved to the bottom of the list of explanations.

Like I said, I went into it with my eyes open. I didn't expect anyone to give me a cookie or anything. It's just that the generalized hostility was unexpected.
Why a 41-Year-Old Record About Fascism Matters Now
Corn subsidies are another market distortion that keep sugar more expensive than HFCS.

Especially subsidies to US "Grade C" Corn serve to keep a lot of corn derivatives incredibly cheap (HFCS, corn ethanol, fatty cattle feed stock filler, etc), because "Grade C" (aka "US Standard Corn") isn't typically considered useful for much more than its derivatives but there is a massive trade in it because of how cheap that corn is.
Is there an argument for ambivalent function definitions other than "keyword" recycling (possibly in a mnemonic fashion)?

I hadn't seen Dzaima's APL, thanks! I like that he made a processing binding; APL always seemed like it would be such an obvious choice for doing dweet style graphics code golfing that I wondered why no one seemed to be doing it. A web-based APL would be a better choice though.
Ask HN: How do you stop selling yourself short amidst negative criticism?
I've heard this multiple times. Don't sell yourself short, if you're looking to find a better job, promotion, whatever you're looking to get from others in life.

I've gotten plenty feedback about my job experience, saying it indicates very slow progress and complacency (and that's just the general idea). Despite all of this I'm also being told not to sell myself short. If your feedback gives you a harsh reality check how can you resist not to? How do you "sell up" when people give you few positive things to say about yourself?
Former Heroku employee. They just released streaming data connectors (https://blog.heroku.com/heroku-streaming-data-connectors) which is pretty cool.
If you're using F-Droid, it helps to switch to NewPipe's own repo, since the default F-Droid repo tends to be a bit slow with updates.
Paul, Dmitry, thanks for the link, the idea of an SQLite-backed spreadsheet with Python for computations looks quite enticing.

Right now, the spreadsheet is unworkable (formulas are updating where I don't want them to, visual editing glitches), hope you iron out the bugs.
I’m fairly certain that yum and apt meet these requirements for “traditional” package managers, I know Maven does as well.

I think it depends a lot upon the culture of the ecosystem, maven being fairly conservative is a natural consequence of Java being very enterprise focused.
Like the old Arthur C. Clark quote goes: “Any sufficiently advanced technology is indistinguishable from magic” -- unless it might be cheating in which case throw them a curve ball.

Kudos to the DeepMind team for making magic happen.
> Grosjean survived due to every person and every piece of technology working exactly as they should.

I think this misses a couple of key points. The only reason his car tore in half and caught fire was because the barrier failed spectacularly. It’s absolutely not supposed to do that. LeClerc had a bigger crash in Monza this year, and it wasn’t nearly as dramatic. So this incident was caused by a piece of safety technology failing catastrophically, with a whole bunch of other safety tech working as intended to save his life.

Also it’s good the marshals and medical crew were there so quickly (as the medical car follows the pack on the first lap). But they basically contributed nothing to Grosjean’s survival. He was completely engulfed in flames for 18 seconds. He survived because his flame protection worked (he got his burns from using his hands to climb over the hot barrier, not from exposure to flames), and because he wasn’t incapacitated by the crash. If he had been knocked unconscious or injured too badly to move, he would have burnt to death in there. The couple of fire extinguishers they had on the car weren’t doing anything to a fire of that size.
"Automakers" aren't hoarding anything. If you read the cited links, the DOT is the one asking to retain the spectrum.

As for it not being used yet: that's because the technology wasn't there yet... The first trial was deployed in 2017. You're the guy declaring electric vehicles a failure in 1990 because battery technology wasn't ready yet.

https://ieeexplore.ieee.org/document/5888501

https://www.fcc.gov/wireless/bureau-divisions/mobility-divis...
WA Notify System Goes Live
It’s not just (or even) ARM. It’s Apple.

For comparison, the A series chips on iOS devices are years ahead of their competitors on the Android side (largely Qualcomm and Samsung) despite all being on ARM.

That being said, it would indeed be good to hear from someone with expertise as to what Apple has accomplished and why others haven’t been able to.
Look at the bitcoin CME futures. The all time open was 20650, and went straight down from there. Closing over that is key for sustained upside
It would be awesome if Biden brought Wheeler back, but I suppose he's earned a rest.
AI = Software and Services?
Hrmf, I may have missed that exact part.
> Those things got cheaper because of advances in supply chains and technology.

That is why things get cheaper all the time, yes.

> Why in the world would I ever loan to a small business if I could see gains just by holding the money?

The same reason you do now, which is the only reason you ever lend money: by lending it (to someone more productive than yourself of course) you gain more.
Yeah, me too, I found that pretty shocking actually. So shocking that I basically didn't believe it, so I tried myself (in C++, but it doesn't really make a difference). With 2000 threads, the computer had no problem whatsoever, the process only took around 16 megabytes of memory and not very much CPU.

So I bumped it up to 20,000, thinking that would probably work as well: the computer immediately crashed and rebooted. I didn't even get the "kernel panic" screen, it just died (this is on a 2018 mac mini with a 3.2 Ghz Core i7). When it turned back on, this was the first line of the error message:

Panic(CPU 0, time 1921358616513346): NMIPI for unresponsive processor: TLB flush timeout, TLB state:0x0

Weird. I really thought that this wouldn't be an issue at all. And: if it was an issue, that the OS would be able to handle it and kill the process or something, not kernel panic.
Why is Apple's M1 chip so fast?
What are the technical reasons why the M1 chip is so fast. Does Apple use any exotic tricks? Can Intel and AMD do the same trick in their chips?
BBC BASIC Console
The only way to do it and to stay sane is to just include your dependencies in your source tree.
Pip supports this now. It calls them constraints files: https://pip.pypa.io/en/latest/user_guide/#constraints-files
On the other hand by being Android you get to run all the Android apps out there.

What I seek in a phone is control over my privacy, not necessarily a vegan FOSS system.

What that means is things like:

- Fine-grained control of permissions to apps (e.g. access to rear camera only, access to only city-level accuracy of locations, access to read from only directories I specify)

- For apps that insist on having permissions to things like location and wi-fi scans to use them, the ability to make the app think it got said permissions, but receives fake data. And no, Android's mock location feature doesn't work, because apps can check if the feature is enabled or not

- The ability to fake IMEI, phone number, contact list, installed apps, and other identifying data

- Ability to generate fake IMU, proximity, temperature, barometer, and all other sensor data that could conceivably be used for fingerprinting
(1) https://transferwise.com/help/articles/2571942/what-countrie...

(2) the countries without infrastructure generally can’t afford to be spending even $6 on a transaction. Venezuela’s minimum wage is $2 per month.

(3) Bitcoin isn't for sending money to CAD, which of course you can do.

Funny how it’s always not for the thing I point out it doesn’t work for haha. Nobody can quite figure out what it is for except speculation and crime.
I wonder if there was a local loudness maximum on the globe diametrically opposed to the volcano. As the advancing wave makes it half-way around the globe, it seems like it would converge simultaneously on a single point on the opposite side.
Iran Nuclear Scientist Was Shot with Mounted Remote-Controlled Machine Gun
You wouldn't, indeed couldn't suddenly inject billions of people as the supply wouldn't be there.

Sinopharm have gone ahead and vaccinated about a million people before full testing with apparently no infections and no serious side effects so it's not that outlandish. https://www.theguardian.com/world/2020/nov/20/china-has-give...
A segment of that segment relies on homebrew.

Plenty of us develop just fine without it.