skysight-inc/HackerNews huggingface dataset:
Yes i read some interesting article aswell regarding mRNA vaccines, but from my understanting mRNA vaccine aren't yet tested in humans right? Only animals or am i mistaken?

EDIT: what my question is: is there another mRNA type vaccine out there fully developed (i'm not suggesting that they are bad!)?

EDIT2: Guys, i will never ask question again in here. Begin downvoted for a genuine question.
You need both things. You need a monopoly in a market, and you need to be using your monopoly position to crush your competition.
A democracy founded on the notion that all white male property owners were equal and slavery was acceptable? Some fancy words in a fancy document doesn't override the actual reality of who was considered equal or not.
For the ML-impaired, how portable is this process? Does it work on other ML platforms? Are the digital assets (specifically this MLMODEL file/bundle) easily transmuted to work with, say, TF?
I used Lineage OS for MicroG and it's by far the best experience I've had so far. Now I'm using a custom ROM supporting signature spoofing (because my new phone doesn't get official Lineage builds) and there are some issues and it was a lot more work (especially learning about signature spoofing itself is just too hard).

Lineage OS for MicroG: Absolutely recommended.

MicroG even supports the bluetooth contact tracing protocol used by the Corona-Warn-App, by the way.
Hi phh,

Doesn't the DRM stop working once the bootloader is unlocked? That'd be a big concern since most streaming apps would refuse to install or work in that case.

What other such changes is Google pushing into Android that discourages unlocking the bootloader / rooting?
For anyone in the UK looking for the same kind of mayonnaise that you get in Belgium, the closest I've found is this Polish one, available from Tesco or your local Polski sklep.

https://www.tesco.com/groceries/en-GB/products/262110048
Show HN: Avoid. The. Burnout
I think the main factor for those - and lots of other 'traditional' chip shops in both Belgium and the Netherlands - is the use of beef tallow instead of the generic 'frituurvet', which is mostly sunflower oil.

I mean don't get me wrong, at home we have a fryer and we make the odd load of homemade chips as well and they are the tits, but it's not the same.

We used to be able to get solid blocks of frying fat, probably was beef tallow or something like that, but it's all saturated fats (I believe) and bad for one's health and the like. According to the wisdom of the time anyway; I don't know, there may have been some lobby behind it (like how the wheat lobby made fat the boogeyman, and now someone is making the sugar / carb industry look bad).
Out of curiosity, what timeframe were your working years? My concern is that "investing mostly in equities" (assuming a decent percent of growth stocks) can be the deciding factor if you happen to hit a good bull run but potentially disastrous if your market timing is off.
Satisfying the BLAS/LAPACK dependency was one of the biggest challenges. I ended up passing LAPACK 3.4.2 through f2c before compiling the result with emcc. PCRE and some SuiteSparse libraries were the only additional dependencies needed for my project and they compiled with Emscripten without too much difficulty. The rest was just hacking GNU Octave's Autotools build system, which gleans a lot of information from the system environment, into working with emconfigure and emmake. My changes to the GNU Octave source code are available here:

https://github.com/rwl/octave-4.4.1/tree/web-assembly
What do you see as the advantage of using these Rust + WASM running on Lunatic processes, versus developing in Elixir?
Here's a possible funding idea: See if you can get one of the big cloud providers or CDNs to notice the project, so they can hire you to build something that goes head to head with Cloudflare Workers.
Giant Japanese robot spurs hopes for tourism after virus hit
It's barely a lockdown. People are still working, going to offices, going to school etc.

Our first lockdown was a real lockdown where the streets were a ghost town. Right now you wouldn't even know it was a lockdown, you'd think it was just mild precautions.
Context is quite important, I agree.

However, when possible, giving _actionable_ info can really help, especially if the user can see that error.

For example, you can try to explain why this file is expected, and give a link to the spec/doc.
Extremely helpful when called at 4am in production.

Alternatively, I've seen some experiments with extreme reproducibility: capture the full context (network requests, filesystem, db state, etc.), and spin up an instance with that state. This way devs can deterministically reproduce the issue, and fix it. But, it supposes that the application is written to support this fairly well (by either being very functional, or by having probes in all non-pure functions).
https://calyxos.org/ is another promising Android fork similar in ideals to https://grapheneos.org/
>>> Anti-vaxxers immediately jump on any report of possible adverse events in a vaccine trial (which are thoroughly investigated, of course).

>>> Let’s spare a thought today for the person who signed up for the Moderna vaccine trial, received two placebo shots and died of covid19.

https://twitter.com/kakape/status/1333401133260419072

---

edit:

Please explain the downvotes.

The vaccine volunteer would be alive if he was randomly assigned the actual vaccine, and not two doses of placebo.

The tweet is from a respected journalist at Science Magazine.
Long time ago in a other galaxy there was a system called "time sharing system"

>The two are huge and novel developments in OS design

Yeah "new" since the 1960 on a Computer called PDP10 from DEC
Never put all your money in any one instrument even if it is a collection of many different things. The foolish part was 'put it in a single ETF'.

Honestly this whole thread is a dumpster fire I'm leaving this one alone.
Gapminder Worldview Upgrader
>Everyone talks about how US tech salaries are inflated values because they don't include the cost of healthcare, a lack of guaranteed PTO, etc.

In all fairness, if you're working for a public tech (and many other) companies, you probably have good health insurance that's at least subsidized and 3-4 weeks of PTO which may not be great by European standards but isn't nothing. (Though admittedly increasingly shared with sick time so if you're out a lot, it's less good.)
I assume this is possible in Rust, so someone please help me understand: why not just print the stack trace?

In my opinion, if you suffer a sufficiently fatal error, you should just crash outright and log the trace + error message. Barring that luxury, you should log the trace + error message, then attempt recovery.

That seems to be what unwrap here would do on its own, so why would that be bad practice (assuming the error was fatal in the first place?). Am I just misunderstanding something fundamental?
Apples to oranges.

The UK is one of the most densely populated countries in the world, 14th according wiki.

Ireland is one of the least densely populated countries in the world 112th.

I see these intercountry comparisions all the time and it makes no sense, every situation is vastly different. I'm in Australia, and know I have it good, but Australia had all the factors going for it, it's easily isolated from inter country travel and it has very sparsely populated cities. It's economy is also propped up with an abundance of natural resources unlike services based economies like the UK.
The worst case is that you spread disease back into the municipal water supply and kill neighbours.
Hi there, thank you for pointing out the sections of the website that got outdated. We'll work on it asap.

However, we still need to defend our use cases... CrateDB has been distributed since the beginning, and it is a very mature technology in this regard. The page you mention is a high-level comparison indeed, but we do talk a little more about Timescale in this post:

https://crate.io/a/comparing-databases-industrial-iot-use-ca...

We worked on this with your team actually, which in fact assisted us in configuring Timescale. They were great -- but CrateDB performs better here.

We've been also in touch with your team with regards to more comparisons with Timescale... As in order to be fair, we wanted to share everything in advance. This is not a Crate vs Timescale war! Still, we believe CrateDB is amazing and we invite everybody to try it: https://crate.io/download/

(... I also work at Crate, hehe)
It hasn't happened to any user yet. Additionally most of the features don't require a Google account because they are replacements (it does allow you to log in with Google however).
The vast majority of the things there are things that few people interested in MicroG would want. The important things (accounts, notifications, maps, SafetyNet) are there and mostly working.
I don't think so, can you clarify?

Edit: Actually, yeah I see your point. To some extent yes, as I'm using the confirmed cases number for Ireland. But when I eyeball the google confirmed cases graph it looks like there's been a 50% reduction in confirmed cases, so my major point still holds.
GitHub is forcing Microsoft to deal with thorny controversies two years after
Here’s the rub: the system is rigged against you. If making money is your only interest, you’re going to be frustrated and in a continuous burnout cycle. American / Western capitalism is dominated by entrenched interests and unless you have an “in” in the form of family connections, a prestigious degree or simply a large bankroll to start, it’s really, really hard to break free. This is by design as it keeps workers desperate while preserving the inter generational wealth for the folks who own everything. This is what is meant by “wealth inequality”.

Some people do manage to “make it” in 2020 but it’s more dumb luck than anything. You can do everything right and fail miserably — this is the outcome for most people with your mindset who chase “get rich quick” schemes. Sounds like you’re having cyclical burnout from smashing your head against the wall because every market is crowded and you have no real way to set yourself apart — again, this is by design. Late stage capitalism and all.

But even if you do succeed, there’s a good chance you find yourself in your mid 30s with a lot of money but poor social skills and limited interests to draw upon. Women / men of this age tend to be attracted to people who are interesting rather than wealthy. If your only passion is how you make a living, that’s kinda dull. You’re 25 and probably have lots of friends now, but by 35 most of them will be married and doing their own thing and you may see them a couple times a year. If you’re boring and haven’t developed interests, you’re going to be lonely.

You can cultivate interests — just do things for the sake of doing them. Once lockdown is over, join a sports league or take dance classes. Do it just to meet people and you’ll eventually find something you like. Money comes and goes with economic cycles and I honestly don’t think the future is very bright economically for most people in the US. Find ways to cope with the existential dread now or you’re going to end up a lonely 35 year old with no friends and few prospects.
> You don't have freedom if you don't have a lot of money and you can't be 100% happy without freedom, at least in my experience, though I know opinions vary here.

The amount of money one 'needs' depends on a lot of things, like cost of living in the area you happen to be in. While US$ 2.5M may not seem like a lot in the US, one can live like a king in may other areas.

One doesn't even need to live in one particular place: people cruise around the world, often spending less than US$ 40K per year in total expenses if you don't get too fancy:

* https://www.instagram.com/sailinguma/

* https://www.youtube.com/sailinguma

Your nest egg would allow for several decades at that burn rate.
Iran's top nuclear scientist was killed by remote-controlled machine gun -report
Because eventually all other values besides profit for 5 companies will be sacrificed if you go down that road.

Why do consumers need the government to enforce child labor laws? FDA regulation? OSHA? These lessons are written in blood.

Yes, you might need to work on the regulation in order to get it just right but "who cares, whatever" is not acceptable unless we want to live in an effectively-communist world with a few vertically-integrated corporations setting all the rules.
Came here to defend my plastic Lenovo. Two years and counting, looks and feels like new. The keyboard still makes me want to just keep typing.
Then that software should add the proper dependencies to their makefile.
Not every error is fatal, and unwrap can make trivial errors fatal.
Apple is also primarily a hardware company, Microsoft has it as part of its business (mostly successful in gaming).
Like you, I haven't used either for serious work in many years but the last time I was doing serious work I found Python to be much faster. I discovered this by accident after porting one of my Matlab programs to Python and noticed an immediate 4x speed improvement. I worked with both for many more years afterward and in my experience Python was usually faster with a few exceptions.

That said, Matlab had great tech support and the sales rep was always super helpful. They were much nicer to work with than say National Instruments.
They should probably phrase it better then - as it stands it's terrible advice.
MSRs are interesting. There are a lot more than are documented, and since they came into existence, people have been exploring them:

http://archive.gamedev.net/archive/reference/articles/articl...

http://www.rcollins.org/Errata/Jan97/Bugs.html
And it isn't just FAANG. Look at Disney and Comcast and all the other conglomerates. The SEC and FTC have totally failed our country in the 21st century.
Funny to think that once x86 was the platform that had too few general-purpose registers, so people sacrificed the frame pointer register in their highly-optimized assembly routines...
All that stuff is emulated in microcode.

And while counting architectural registers is something, in reality modern out-of-order processors do something called "register renaming" so that more registers can be used on-the-fly as it dynamically creates a data flow dependency graph. Yes, inside each processor.
No "best" fry exists just as there is no single most attractive piece of art. It's all personal taste, which is why the author is trying to replicate something.

There's no disputing taste.
the C code is compiled to WASM bytecodes, they are interpreted in a WASM VM. If the C function crash, it does it inside the VM, so the crash is contained.
I’m also ML impaired, but would people really train the model on a Mac? Surely you would want to train in the cloud or on something with a proper discrete GPU. It seems that a better article would be how to take e.g. yolo and convert it.
>As an example of this I do wonder if the PC industry realises the bind they’re now in with the Apple and the M1.

Apple has had their own chips before and the PC industry is fine. These sort of things are always cyclical. It's easier for Apple to do the M1 when it's a shiny new thing than keep innovating for a decade. Eventually someone will come up with some innovation they can't match and it will swing back towards integrating commodity parts.
Yeah but imagine being dumb enough to get infected and very sick over the next month before you can get both shots next year. Because there are going to be thousands, maybe millions who do that in the USA alone for no good reason.
can any one suggest me which is the best tool for rewriting an article i have tried many tools but nothing performs
I guess exaggeration doesn't come across well over text. I was trying to get across that it's super irritating. No I don't actually want to punch my computer...
> Hopefully at some point we will understand that the virus will follow its own curve regardless of what we try to do, after it has implanted in a country.

This is just straight up wrong. Many countries like China, Singapore and Australia have gotten sizable outbreaks (tens of thousands of people) under control and effectively eliminated the virus in their territories.

I do agree that half-assed lockdowns are the worst of both worlds: you endure the economic damage of shutdown without putting much of a dent in the case count. That said, with mass vaccination on the horizon, even pushing back the peak by a few months is about to start having real benefits.
I think if something is trully obsolete is already removed from hardware and emulated by the CPU with microcode.
If you remove the obsolete stuff from x86, there will be no point to keep this old ISA altogether. One of the selling point of x86 is legacy support.
The positive side to a stubborn scientific community are the money making opportunities it presents. For those who were able to get past the doom and gloom of the media and scientific communities 2020 has been a fantastic year of growth
This is actually why I dislike Python so much. The "try first, ask forgiveness later" truism has infused itself into the core language design and surrounding community. The end result is unexceptional exceptions and the presence of a dozen "warm" paths.
Because I'm being colloquial. Hopefully nobody is making important decisions as a result of my HN posts ;) (If you are, contact me and give me some money :))
Antisense drugs are the same biological material, but have a very different mechanism of effect.

Specifically, mRNA vaccines require an immune response to be effective. The mRNA (vaccine) encodes a viral protein, and the host (human) immune system still has to learn to respond to that protein.

Antisense drugs are much simpler, with no immune response required. The mRNA (the drug) itself simply binds to the target mRNA.
It seems to me that directing one's efforts toward making a positive impact on the world is more fulfilling in the long run. Moreover, there are many ways to get to that goal, that could include substantial profit (a startup that creates real value, a successful academic career, senior management in a big corporation that does mostly good things, etc.)
Focusing only on money may result in getting money. But money is only a means to an end. I find impact an end in itself.
full support.
Regarding your third source: All of the countries you selected on this graph had a strong but not identical drop. Germany for comparison took only very light measures (schools and daycare close to 100% open) and has seen a much smaller drop.

(1) https://ourworldindata.org/coronavirus-data-explorer?zoomToS...
Australia on average is very sparsely populated. However, it's also one of the most urbanized countries in the world, and places like central Sydney are hardly "very sparsely populated".
I may consider eleventy in the future as it also supports EJS. It is the template language that I am most familiar, no context switching for my brain. My blogging platform is simply some EJS files glued together with Express. super simple.
Airbnb and DoorDash Are Said to Target Higher IPO Valuations
Analyzing coffee grind size consistency and distribution
I'm not sure; Coca Cola could start investing money and start buying up other food & drink brands.

I mean could you have imagined 10, 20 years ago that Disney would start to gobble up other companies like some weird Shoggoth monstrosity and multiply its stock value by 5-6 times?
Note that while it's theoretically a fork all they do is apply around 2 patches for signature spoofing and include microG (all automatically, so you're in sync with the official LineageOS).
Are their used batteries in such high demand?

Yes! Used Nissan Leaf battery packs and individual cells sell for quite a bit.
Yes, and same with fracking. Documentaries like Gasland have gotten some deserved criticism because there is evidence of methane and natural gas coming out of water pipes/wells way back at the turn of the century. But that doesn't dismiss the other points of fracking fluid being incredibly toxic and how they will destroy watersheds (you can't just pump that crap into the Earth and say 'well it's below the water table' .. how do you even know?!)

I do agree electric vehicles are a pretty big lie. You can't buy yourself out of an environmental disaster. We can't just consume more. The "Green New Deal" is about replacing tons of buildings and infrastructure that are perfectly fine, and will cause TONS of new waste in an effort to .. reduce waste.

The best thing you can do for the environment: don't buy a new car. Just keep driving your current gas vehicle and maintain it (so long as it was made within the past 20 years with good fuel efficiency) and when you do decide to toss it for an electric: buy a used one if possible.
> what the hell happened to make the English lockdown so ineffective

The word "lockdown" is being used for everything from "welding anyone with a fever into their apartment" to "a mild suggestion that people work from home if practical." Any reasonably restrictive lockdown which minimizes time spent outside one's own home and limits travel between regions is, if enforced, going to rapidly reduce R-values, and shortly thereafter, active cases.

Unfortunately, many jurisdictions aren't willing to accept the financial losses from such a lockdown, and so institute something between a token effort and a sham, invariably following it some weeks later with a declaration that "lockdowns don't work."
Faster PostgreSQL Counting (2016)
> Pretty difficult to have an open web without a libre browser?

Donations to the Mozilla Foundation don't fund Firefox development, unfortunately.
Ask HN: Windfall at IPO. How can I manage?
I’m expecting a windfall from an upcoming tech IPO. I run a tech startup and have been angel investing in other startups since many years.

I’m a business angel in the mentioned IPO and have no lock-up period. I had liquidity events in the past but not at this size. I dont’t plan to sell at IPO nor need the cash. I believe that the company will 10-20x over the next 10-20 years and would love to hold the shares.

That said, I think this is not optimal for my portfolio. Possibly even idiotic. I’m wondering what the optimal play in terms portfolio construction is.

Reading and analysing the data [0] on IPOs over that last decades suggests that I should sell all shares on a schedule, like over 18 months [1], and reinvest in new startup deals.

Who has been in a similar situation and can point me in the right direction?

I do not want to retire. I want to keep investing in startups.

[0]: https://site.warrington.ufl.edu/ritter/ipo-data/
[1]: https://blog.wealthfront.com/sell-employee-stock/
Show HN: Owwly – Find first 10, 100, 1000 users by sharing your tool's progress
Great read, I think understanding what drives this hustle culture, especially in Silicon Valley is probably a good starting point. I’d posit it’s entirely driven by viewing money as a measure, it’s your score in the game of life. At least for lots of other people I’ve met, hustling more equates to wanting to feel superior to people around you, to demand that respect because you have a high score.

I’d also posit the OP intuitively understands this and is why they’re looking to “fix” it, why they think this is a problem because it feels like it should be one. And I personally agree, there’s no added meaning to life if you’re only looking to be better than those around you. One day I imagine you’ll realize there’s no winning or losing, there’s just life. It goes on.

I think mindfulness can address a lot of the concerns here.
I’m 65, have $500k in cash, no ‘impressive’ work résumé – can I retire?
We're planning to start working on it in January, and I think we can get the first version out in late February. If you know good senior Android engineers, send them my way! (charles@bunch.ai, no CV required, let's just chat)