skysight-inc/HackerNews huggingface dataset:
Exactly this. The problem of the public being deeply divided on this topic isn't a problem with the topic or the science surrounding it, the causation goes the other direction. Deeply divided public is deeply divided on every issue, it all becomes a proxy for political ideology.
We changed the title to that of the article as the site guidelines ask. Submitted title was "DeepMind Solved Protein Folding".
The non-uniform memory performance of such a solution would be a software nightmare.
Unfortunately, even intel’s white label laptop specs soldered RAM, so I expect the trend to continue in low/mid range PC laptops.

https://www.theverge.com/2020/11/19/21573577/intel-nuc-m15-l...
At least for C# ASP.NET it's basically what you described. There's a few optimizations, for example the threadpool has pretty smart autoscaling to maximize throughput.
This is what China did and it seemed to work pretty well.

Though given how hush hush China is about everything, it's also possible they've had a vaccine they've been using on their population for a while and just deigned not to tell or share.
From https://www.goodrx.com/blog/flu-vs-coronavirus-mortality-and...

2017-2018 Flu 2018-2019 Flu COVID-19 as of August 27, 2020
Cases 45 million 35 million 5 million
Deaths 61,000 34,157 180,000+

Further reading on how the flu and COVID-19 differ: https://www.cdc.gov/flu/season/faq-flu-season-2020-2021.htm
> But Apple has a crazy 8 decoders. Not only that but the ROB is something like 3x larger. You can basically hold 3x as many instructions. No other mainstream chip maker has that many decoders in their CPUs.

The author completely misses "the baby in the water"

Yes, X86 core are HUGE, the whole of CPU is for them only.

They can afford wider decode, even though at a giant area cost (which itself would be dwarfed area cost of cache system area.)

The thing is, have more decode, and buffer will still not improve X86 perf by much

Modern X86 has good internal register, and pipeline utilisation, it's simply they don't have something to keep all of those registers busy most of the time!

What it lacks is memory, and cache I/O. All X86 chips today are I/O starved at every level. And that starvation also comes as a result of decades old X86 idiosyncrasies about how I/O should be done.
Uranium isn't necessary. A breeder reactor could manufacture plutonium, or a thorium fueled design could be used.

Nuclear power isn't constrained by fuel scarcity at all. If anything, we have too much fissionable material.
I mean, he literally followed it up with Rising Sun.
Day 192 of lockdown.
Comments moved to https://news.ycombinator.com/item?id=25253488, which was posted a couple hours earlier.
> As people are thrown out of work as a direct result of lockdowns, and as more and more families find themselves unable to cover their rent or food, there have been sharp increases in domestic violence, homelessness and illegal drug use.

This line of thoughts is quite puzzling to me. Domestic violence, drug uses are independent issues should be fixed by themselves.

In face of grave danger, there is always a balance to make, and usually their danger is so high that it usually has a overriding effect. This type of balance is not unique to covid, it literally happens everywhere all the time.
Very good point! To avoid anyone having a dead relative, I think we should all stay inside until no one ever dies again, for any reason. If you disagree, you literally want to kill grandma.
I would agree with you that there is some coverage of these issues...lately. Yesterday for instance CNN ran a story about the suicide trend in Japan. However there was very little coverage of the secondary effects until late in the summer.
> Still, I find it gratifying that my least favorite instruction set of all time may finally be going the way of the dinosaur.

Only I fear it won't be replaced by anything more open.
Brilliant. Ad-hominen attacks because you cannot stomach the facts. Would those facts be more palatable if they were from a channel called GodIsGreat?

You could have watched the video and rebutted the facts that are inconvenient to your version of reality.
Url changed from https://predictioncenter.org/casp14/zscores_final.cgi, which points to this.
>I do think that entirely too few people in the US have ever tried anything other than fries of smaller cross section

Unless the American eats only at fast food restaurants (which is probably a decent sized group), then I can't imagine that to be true. There are fries with many difference cross section sizes even in a regular grocery freezer aisle.

And many restaurants frequently serve fries ranging from skinny shoestring to full on "potato logs" that are easily an inch diameter cross section.
it's to prevent injuries to your thumbs/wrists.
I understand, you've made up your mind; I think I had discussion with you previously, but I will still leave some comments.
First of all, we still do not learn much about long-term consequences of COVID infection among less vulnerable population, there is a growing list of documented complications of even mild cases of COVID, so I do not think there is anything obvious in measuring the risk, even if you think otherwise. Secondly, evidence for mask significantly outnumber contrary papers, and it is some kind of cherry picking to fish for the single papers claiming the opposite. Thirdly, risk of you going to the wedding includes the risk of the spread of infection to people you contact with, among them your elder relatives.
And the argument about the inconvenience and facial expressions - well, I do not know who would buy that.
New Zealand is an island with more sheep than people.

The pop. density of NZ is 15/km2. The pop. density of France is 119/km2. France also shares land borders with 7 other countries.
One Big Idea
The whole principle of CISC (v RISC) is that you have more information density in your instruction stream. This means that each register, cache, decode unit, etc. is more effective per unit area & time. Presumably, this is how the x86 chips have been keeping up with fewer elements in terms of absolute # of instructions optimized for. The obvious trade-off being the decode complexity and all the extra area that requires. One may argue that this is a worthwhile trade-off, considering the aggregate die layout (i.e. one big complicated area vs thousands of distributed & semi-complicated areas) and economics of semiconductor manufacturing (defect density wrt aggregate die size).
Correct, as history has shown (in the US), any help for anybody besides corporations is demonized as socialism.
Really fast and easy to use.
#1: The writing's on the wall for x86, probably. Once its former monopoly rent is only justified by high-end "scientific computing" uses -- well you know what happened to IBM/DEC/SGI/HP and their workstation solutions...
Gnome Circle Officially Announced for Letting More Apps/Libraries “Join Gnome”
A good example that free money from the sky rarely bring fortunes...
We can also compare it to the 1889 "Russian flu" pandemic. It killed about a million people worldwide and in most places there were no significant restrictions on people to control it. There is now circumstantial evidence to indicate that pandemic was not caused by influenza at all, but rather by another coronavirus.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252012/
What do you mean with "8-wide instructions", and what does that have to do with multiple decoders?
FYI - This was Windows 10 ARM, not Intel. It is an important step and shows promise, but it is a much bigger (or impossible?) task to run the Intel version of Windows on an ARM VM. That is still a deal breaker for some people.
Interesting, where do you find the size of these dies? I was really curious about how large the Firestorm cores are compared to say Zen3 or Intel cores.

How many cores do you think Apple can realistically add? Can they get up to something like threadpiper. or are we talking more about something along the lines of a 12 core upper limit?
I lived in the Bay Area for about a decade before moving away to be closer to family a few years ago. I have zero regrets for the time I spent there. I met a lot of great people. It was a great place to start out in my career because of the abundant job opportunities. The weather was fantastic.

Of course SF is not to everyone's taste, and maybe you are indeed better off for never having lived there. But for all of its recent problems, there were good reasons that people continued to move there in droves. And I am thinking this current shake up will be a good thing for the city, relieving some of the pressure on the housing market and opening up new opportunities for people.
However it also means zero copy between them too, there are benefits.
I'll let you have the last word. Have a nice day :)
All: there are multiple pages of comments; if you're curious to read them, click More at the bottom of the page, or like this:

https://news.ycombinator.com/item?id=25253488&p=2

We changed the URL from https://predictioncenter.org/casp14/zscores_final.cgi to the blog post, which has more background info.
By the time docker, virtualization, and programming environments are mostly sorted out, there will likely be a successor to the M1 on the market, so while I'm not GP, I do agree with the sentiment in this case. Especially with an ISA change.
If that is truly your point of view isn't is foolish to share it (from a game theoretic perspective).
I've seen Slack, HipChat, Slack (round 2), Flock, and now Teams in as many years, at the same employer. I can't even say anything snarky about the people making these decisions because they're so far up and removed from us developers, I don't know anything about them. The whole thing is just comical now.
There definitely was a downfall of the middle class! Why do you think we had Occupy Wall Street, and why are populists on the left and right, like Sanders and Trump, gaining in popularity? Why did Andrew Yang and Bernie Sanders poll highest among Trump voters? It's because the real middle class of blue- and white-collar work at a stable career has been vanishing. Much of this is due to bad trade and jobs policy, some is due to automation.

The number skills that are useful today are also less than they used to be. The need for actually skilled manual labor has been outsourced to China, Taiwan, and increasingly India.

And don't forget the swindle of universities — 18 year olds signing themselves away to lifelong debt to party, drink, and learn at an institution that couldn't care less about their future prospects. People who leave college with degrees in anything but highly desirable fields are learning they've been lied to about the importance of a degree.
Dictatorship of the Proletariat is pretty famous...
All I got was that reading Harry Potter gives you Ringworm?
> underwater basket weaving

Do such smart people really still think this of subjects that don't have a pre-drawn straight line to a comparable paycheque to their own?
These guys are almost certainly used to operating for extended periods on high adrenalin doses. That helps keep you focused on your task even when you see something like this happening. The letdown comes after the race is up.
Was the internet rationing in the EU even necessary, or was it just a knee-jerk solution to a problem that didn't actually exist? At the time it seemed like the latter. Presumably Amazon, Netflix and friends are back to full bitrates now, has it caused any problems?

Edit: although if the EU requests to slow down data were totally unnecessarily it certainly doesn't disprove your point about excessive regulation
We may not have a satellite at 180 degrees, but we have STEREO A and B at 120 and 240, used along with the SDO to give us a pretty full view of what’s going on
The list of malicious sites is probably the safebrowsing block list in Google chrome. gvt1.com is a Google site used to download various Chrome related assets. Marktext uses Electron so it is automatically downloading these.

EDIT:
After decompressing http://r4---sn-8xgp1vo-xfgs.gvt1.com/edgedl/release2/chrome_...
(linked in the Github issue) and looking at the manifest.json, this is an extension called "Crowd Deny." Reading https://forum.vivaldi.net/topic/43831/crowd-deny-what-is-it/..., it seems to be used as a blacklist to stop push notification spam.
This is what Wuhan is like now: https://youtu.be/OyHt7-KmK7Y

They had about two months of strict lockdown. What you see in the video is the result.
Well, people obviously can say, that this harm cannot be taken seriously on the societal level. Unless you have some psychiatric issues, obviously.
x86 instruction-length is not encoded in a single field. You have to examine it byte by byte to determine the total length.

There may be internal fields in the decoder that store this data, I suppose.
This reminds me of the Amiga which had FastRAM and ChipRAM. It was all main memory, but the ChipRAM could be directly addressed by all the co-processor HW in the Amiga and the FastRAM could not.

It would be sort of interesting for Intel/AMD to do something like this where they have 16GB on the CPU and the OS has the knowledge to see it differently from external RAM.

Apple is going to have to do this for their real "Pro" side devices as getting 1TB on the Mx will be a non-starter. I would expect to see the M2 (or whatever) with a large amount of the basic on chip RAM and then an external RAM bus also.
Yeah, it’s a fair point. The idea of those armco barriers is that they act as energy absorbers, crumpling to lessen the shock. But in this case, they basically tore the car in half. Martin Brundle made the point during the commentary that a concrete barrier (which they put up to replace the armco) would allow the car to skid along it. You could also imagine safer energy absorbers, like barrels of water or tyre stacks.

Clearly, this crash needs to be studied to see if any new safety regulations are needed for those kinds of service roads that jut out next to high speed straights. I have every confidence in the FIA to do that (both the halo and the VSC resulted from studying Jules Bianchi’s fatal crash). As far as safety goes, the FIA is (IMHO) one of the most responsible and trustworthy sporting organizations in the world.
This model will be an amazing tool toward a science of protein folding, but we have not "solved" protein folding as long as that remains elusive.
The protein folding problem is predicated on the idea that there is a ground truth (a single static set of atomic coordinates with positional variances). If your point is that even experimental methods can't truly reach 100% (due either to underlying motion in the protein, or can't determine the structure), that's more or less what Moult is saying (they more or less arbitrarily define ~1A resoution and GDT of 90 as the "threshold at which the problem is solved").
> The term Post-PC was first coined by MIT scientist David D. Clark in 1999 and was quickly adopted by both Microsoft’s and Apple’s former CEOs.

Up to a point, Lord Copper. See (once again) Jobs' discussion of the "Digital Hub" concept at Macworld 2001 San Francisco https://youtu.be/AnrM4n6S3CU?t=2585 . This January 2000 Fortune interview https://money.cnn.com/magazines/fortune/fortune_archive/2000... is also relevant. It also turns out that Walt Mossberg described the Newton as 'a sort of “post-PC” device' in 1993: http://allthingsd.com/19930812/the-apple-newton-messagepad-r... .
This is a bit much for me to read without the right background. I'll focus on your claim, though.

"Sending mRNA to human cells to produce viral proteins" describe how all of the other vaccines work. You're saying that this one uses DNA. I don't know if that's a typo or if that's an important difference. However from what I understand, the two other vaccines people are talking about don't change any of the genetic material in your cells. They just send other genetic material that makes use of the translation equipment in some of your cells. It sits next to your existing genetic material, and then (I'm guessing?) just goes away.
> Bernie Maddoff said the same thing. He also tried to create a perpetual motion machine.

Bernie Madoff doesn't get to print his own currency, you see why that's different right? You know who does though? Tether.

> Canada has been lending everyone $2000/month this whole time.

Paying. Lending implies that it has to be returned, it does not.

> Again, you don't understand what bitcoin is, nor money apparently.

Incorrect, I know what money is for and how it works. I don't disagree with anything you said about money. What I disagree with is that inflation matters in that context. It does not. I also see Bitcoin as having been spoken for already, and it has. with a worse wealth distribution than a banana republic, which it has.

> Yes, the "experts" managing the "economy" right now are doing such a great job.

Inflation has been in a tightly controlled 1-2% range in the US since the 1970s. They are. So forgive me for not giving a bunch of un-elected, un-accountable randos with commit privileges and a narcotics trafficker the steering wheel lol.

> At some point, sooner rather than later by the looks of it, it will be the only solution.

Agree to disagree.

> Weird advice from someone convinced we'll never have to pay back our debts.

Who is "our" and why does one have anything to do with the other?
Ah ok, I see. I have a "confirmation-thank-you" page, but it's behind a one time token that is only in the email and only valid for 48 hours. And once it's validated the token is no longer valid, so there is no way to get further information.

Once confirmed there is no other public page or anything to get a hint if the email got validated or not.
Almost everything works if you start terminal in rosetta mode.
cmd+i on terminal.app and check the rosetta box.
> The question is, is it worth the risk of going to indoor weeding? At least for me its obviously yes.

This opinion is one primarily born of ignorance.

> the article pointed out research paper that says there is no strong evidence that mask help.

I'll err on the side of caution because I understand the consequences.

> For some, yes, for start it can be uncomfortable to wear, it can even be more uncomfortable when exercising or in hot weather. Not to mention you lose clue from people facial expressions.

So, no.
He's a good demonstration of why experts without ethics are problematic.
Depends on the workload. Compilers are famous for being branch heavy and random lookups... something that people have reported excellent performance on the M1. Parsing is hard as well (like say javascript).

Of course for any CPU workload it's going to be harder on the memory system when you have video going on. Doubly so for a video conference (compression, decompression, updating the video frames, streaming the results, network activity, reading from the camera, etc).

Seems like the apple memory system wouldn't have received as much R&D as it did unless Apple though it was justified. Clearly the speed, performance, and price show that Apple made quite a few good decisions.
With bitcoin the choices seems equivalent to unsecured banks (trust someone else), or gold bars under the mattress (hope they don't get stolen, you don't get incapacitated and they get forgotten about, etc). I wouldn't want to store a significant chunk of my savings in either of those situations.
wow that is surprisingly not terrible
Agree 100%. I spent a week driving across the Salar and the surrounding desert in 2010 [1], it was one of the most wild and unforgettable experiences of my life.

All around the world places have parallels or similarities. Patagonia reminds me of Alaska. The Sahara is a bit like the Simpson, white sand beaches in Northern Australia are similar to those in Thailand or the Bahamas.

Not so with Bolvia. I've never seen anything on the planet remotely like the high Altiplano around the Salar and the entire South Western part of Bolivia. It's utterly breathtaking and unique.

[1] http://theroadchoseme.com/the-uyuni-salt-flats-to-chile-1
Recursion isn't the problem. Not keeping track of seen tweets is the problem. Recursion can be used to detect cycles and traverse a cyclic graph in a way that doesn't blow up.
They also break https://twitter.com/mauritscorneIis/status/12668346972560875...
I am glad I am no longer living in San Francisco. Going to work there is like the tech equivalent of going to work at an oil rig.
You've mentioned "Low risk" a few times. You're right, the risk for young people is low. That doesn't mean no-risk though. There are plenty of examples of young people suffering harm because of covid.

A TIA at 23 isn't a trivial thing. https://twitter.com/RileyBehrens/status/1333230792206553089?...

At the moment we think covid is at least ten times more lethal than flu. If you're comparing numbers of people killed you need to make sure you're counting death the same way, and most people aren't doing that.
Are there any technical measures preventing the creation of a market for those alternative currencies, or is it just a TOS thing?
It takes time for secondary effects like that to show up. But I recall reports of large numbers of restaurant closures as far back as late spring.
For a fact? I don't unless it actually happens (schrodinger's cat), but there's a high probability this would be the case rather than not.

Will people still get infected? Yes, I'm sure they will since typical face masks are not P100. But when you're preventing ~80% transfer on an exhale and ~60% on inhale, if both participants had masks on then that filters a lot.

Granted this assumes other precautions would be followed as well since obviously places like bars and restaurants where you have no mask on will continue to be an issue.
Here's what I mean:

genrule(name = "oops", cmd = "date > $@", outs = ["oops.txt"])

This is admittedly contrived, but sadly not unrealistic.

Again, I am not picking on Bazel here. Correct builds are difficult enough to get right even when everyone involved wants to keep the build correct! But, the reality is that a lot of real-world build conditions can be downright hostile. (did you know that ext4 vs xfs can change the order JARs in the same directory are loaded off the classpath? I wish I didn't!)
> I think most Gibson cyberpunk failed to capture the banality of the future, because they were fixated on the romantic cowboy-gangster hackers outlaws who lived on the fringes.

This is both an excellent encapsulation of where cyberpunk missed the mark, and why its appeal is so enduring today.

The real-life cyberpunks of the 2020s aren't staging dramatic data heists or getting in firefights with megacorp-employed super-soldiers; they're selling fake social media accounts for pennies or hanging phones in trees to game Amazon's gig delivery system. Gibson was right on the money that "the street finds its own uses" for technology; his mistake was underestimating just how pedestrian both the tech and those uses would be.

In its original milieu, cyberpunk was an escape from the technological unknown. Today, its' an escape from the technological all-too-well-known.
And the conclusion was that based on the data they were not able to determine if face masks protects you from infection or not.

For some reason this has led to media concluding that face masks do not protect you but that's not the same.

Another important effect of wearing a face mask is that it may protect other people from being infected by you but that effect was not part of the study.
My question is mostly just "how do we draw the line in the sand?"

The fact is that if mask-wearing and lockdowns prevent the spread of this virus, they'll work for the flu too. If there is a moral imperative to use these methods for COVID, why would there not also be a moral imperative to use them for the flu?

Where do you draw the line?
Regarding vertical integration, I wonder if their owning the OS and the hardware stacks lead to special insights on what would lead to better performance.