skysight-inc/HackerNews huggingface dataset:
If you had millions of dollars, you'd still need to brush your teeth. And sleep and eat and shower and use the toilet. Would those things mean you're not truly free?

You'll always be 'forced to work' even if that work is just keeping your body alive and well. Perhaps it would be worth trying to find happiness now, rather than hoping it's hidden behind the next achievement.
The rules are even weirder than that. The advance tax credit doesn't have to be repaid even if 2020 income makes one qualify for a smaller amount than actually received or for no payment at all. But if 2020 income is low enough to qualify for a higher payment, you do get to claim the difference on the 2020 tax return.

Even weirder, if your payment would be different between 2018 and 2019 income, the actual payment the law granted earlier this year depended on which returns had been filed at the time the IRS determined eligibility, with no adjustment for subsequent filings.

I qualified for my full payment based on my 2018 income, would not have qualified for anything based on my 2019 income, and did not expect to qualify for 2020 either (although the impact of the pandemic means I actually would). I made sure not to file my 2019 tax return until after I got my payment.

Very badly designed legislation, though there may not have been much alternative if they wanted to act quickly.
Getting from DNA structure from tissue samples is relatively straight forward.
DNA -> RNA -> unfolded protein is basically one-to-one mapping in most cases.
How protein functions depends on how it folds into itself. Once you solve protein folding, you can take DNA sample and see the structure of the molecule without working in lab using crystallography techniques.

Solving protein folding is huge, Nobel in chemistry scale achievement. It would be massive leap for biochemistry.

It seems that Deep Mind solved competition benchmark and made huge leap, but it's just partial solution that works on limited set.

After you have solved protein folding, there is still problem of solving chemical interactions between molecules accurately. Quantum chemistry is extremely compute intensive.
It's apparent Homebrew devs got early versions too from reports like https://gcc.gnu.org/bugzilla/show_bug.cgi?id=96168#c11
The closest we ever got was in a recent stream with Ron Gilbert himself (from https://gamehistory.org/monkeyisland/). Jump to 4:29:23. If only there wasn't a cutscene :-)

https://www.youtube.com/watch?v=ikaqus5_QIg&t=269m23s
A Woman Called ‘Hey’
Show HN: Reimagine the File System
How far does the similarity extend? Specifically, the big question for me is whether AlphaFold will be freely available like ImageNet, or proprietary.
Right. It's fine for me since I use free software as much as possible anyway. The only applications I've sideloaded are WeChat, Teams, Discord, Target, Instagram, and WhatsApp, all of which work fine.

Edit: and Google Maps. The built-in mapping software doesn't have good enough traffic estimation.
Actually it’s normal for heavy machineries to have separate low voltage power for computers and high voltage large current for actuators. Even open source 3D printers has provisions to do that if so desired.
DevRel: The Basics
If you forgot how to do long division, but still had a calculator, wouldn't the calculator still be useful?
Consider your inexperience an asset in this context. The changes and the code should be (to some degree) self-explanatory.

The star may crank out code like no other, but chances are they don't want to maintain it.

So the review from your side can help to relinquish that responsibility.

The point is though, there needs to be common understanding in that matter. (Also that it'll will take your time). It might make sense to talk about that with your colleagues and find an agreement.
Yikes! I'm surprised by the number of people who think temp RAM disk for QA testing came from using containers or the cloud. It was actually in use prior to that technology. And, it was popularized in the use of remote PXE installation which required modifications to the OS after the fact.
If you can explain how gravity works in a quantum level you'd deserve a Nobel. It's not 100% solved, Newton's Laws of Motion are a model, not a solution. Just like the vast majority of science.
Isn't that the role of a big company?

Everyonce in a while, an acquisition goes well, but usually it's like a private equity buyout; you know it's not going to end well, you just don't know when. Except if it's Oracle, then you know you need to start migrating immediately, cause you can maybe get one more contract renewal in before the terms change.
Food insecurity and food bank use is at record highs among US residents this year. That's a considerably better indicator of real economic health than any index.

https://www.theguardian.com/food/2020/nov/25/us-hunger-surge...
Cyber Monday InfoSec Deals
320 pages (almost 100,000 words) is short? I need to re-calibrate. I know I'm a slow reader but anything that I can't finish in a day (about 10,000 words) is "long" for me.

I agree, one of my ALL TIME favorite books but the second half took me weeks to get through.
Europe wants to prohibits unjustified geographical restriction
How to create a gemlog (Gemini log) with gssg
Ask HN: How would solve in-company disputes?
I work at a place where disputes between departments have reached the point I've never seen before: managers forbidding employees to talk to other teams.

Maybe I'm very unlucky, but all the jobs I've so far, with companies ranging from 50 to 10000+ employees, have always had at least 2 departments that actively sabotaged one another.

Is it ever a solvable situation? Imagine you are a person of influence/power in a company like this. How would you go about dealing with this stuff?
Homebrew does have a policy of not having downstream patches, so that source trees upstream have to have the Apple Silicon fixes.

That makes the process much more complex.
Up next: Pacifiers help 45% of stressed adults to cope anxiety, says study.
Sure, you can find this flavour combination anywhere, but I don't know of another country that uses sugar to the extent America does. I ordered a fried breakfast in an American hotel and they put icing sugar on the sausages! It's bizarre.
I remember my surprise when I learned EVs have regular car batteries in them.

The funny thing is, I can imagine a future where "jumper cables" isn't a hefty set of thick wires intended to supply the current needed for a starter. Instead, people will have a 20' long cable with cigarette lighter plugs on both ends. The HV relay can't require that much current to close, right?
No it isn't. Canonical now offers a SaaS solution named again Anbox-something but it's not based on the original Anbox, it's just the same concept of running Android apps but in the cloud for development purposes.
+1 for Understanding the Weird Parts

It's a good course that explains things from first principles.
I wore a mask around other people, and attempted not to cross paths with others.
My prediction on how this will play out is that it will become impossible to exceed the FAANG based on compute price, as the article also points out, but I predict that it won't matter as much. If Amazon has a 50% cost advantage on AI by producing their own chips, then an algorithm working 2x as effective but inaccessible to Amazon would be enough to catch up.

So my prediction is that as chip designs get more exclusive, algorithmic research will become more important again.

Everyone is using interpreted languages because CPU time is still considered cheap. So if you want to prepare for this future as a coder, learn C++ or Rust.
LOL, having worked with SF for the last two years I can completely see them killing the free plan. They care only about licensed seat count, at ALL COST!
Stone fruit, also in the Rosaceae family, also hybridize pretty easily, and a lot of hybrids like apriums are sold commercially.
You can't always make everyone happy.
Because only the experts in this field get to tell us, the laymen, what "solving the protein folding problem means", and they defined it not as "perfect" but as "more than good enough to be acceptable as correct result". Which this did.

X has actually solved Y. That's not so much "massively cool", that's historical.
Great talk by an inspiring man.
Meanwhile, my tax return has yet to arrive. I was pretty patient because I knew this year would be a complete shit-show for the IRS (as it has been for everyone else), but now I am starting to wonder.
Russian Elbrus machines (VLIW afaik) run Linux natively.
Still much faster than synthesizing the protein and then doing NMR or cristallography to solve the structure puzzle what easily takes half a year or more (and very expensive equipment).
> India isn't a unified secular democracy (at least constitutionally) because of Britain, but in spite of it.

I agree. Not sure why you were so upset. I didn't say britain made india a democracy. Britain didn't bring democracy anywhere it went. I just said Britain praises india's democracy because it keeps india backwards and weak. And india just keeps sticking with something that hasn't worked for decades because the leadership is desperate for that pat on the head from their colonial masters.

What's better? China where hundreds of millions are out of poverty but britain calls it a "dictatorship". Or India with hundreds of millions are in poverty but britain praises it for democracy?

> As for India being a member of the Commonwealth, it was by Nehru's insistence that it be named the Commonwealth of Nations, and not the Imperial Commonwealth as Britain intended it to be.

Who cares about the name? A pile of shit is still a pile of shit whatever you call it. The Imperial Commonwealth is still the imperial commonwealth whether it's called timbuktu. Would the british empire be any different if you called it anything else? The japanese tried to call their empire "Greater East Asia Co-Prosperity Sphere". I guess it sound more benign than Empire of Japan but it doesn't quite flow off the tongue.

It's the british empire. The head of the state is the british queen. It's located in london. The language is english. It's the association of "former" british colonies and their master.

https://en.wikipedia.org/wiki/Commonwealth_of_Nations

India represents over 20% of humanity. It should be a free nation and a permanent member of the UN Security Council, like china. Not a pathetic colony of britain. More than 70 years after independence, india is still a colony. That explains its rather terrible situation.

Interestingly enough, almost all of the world's poor without electricity, plumbing, etc are part of the british empire today, I mean commonwealth of nations. What a wonderful association to be a part of.
surprisingly rich article. i got a lot out of it.
Extracting a Gameboy Cartridge ROM Using an Arduino Mega
TIL I learned about an entire Intel microprocessor subsystem, MPX, that was added and then deemed useless before I learned about it. It is both less secure and slower than software solutions. What a failure in processor design.
> In the end, the alpha wolf is an alpha wolf because he's resourceful.

I don't think so... In your context, it's simply alpha wolf = parent wolf, and not necessarily parent wolf = resourceful/strongest/wisest wolf. Most of the time, the "alpha wolves" just happened to be parents, nothing more, nothing less.
Apparently, many of the middle class invested in the market according to reports [0]. Maybe not the best form of savings for some, but I’m not here to argue one way or another.

[0] - https://www.cnbc.com/2020/05/21/many-americans-used-part-of-...
I wonder if the IRS even thinks about a monetary ROI. Given how often poorer people are audited, I'm guessing it's all about cases closed or numbers audited and has little to do with amounts. IMO, amounts would be the better focus.
So, how do search every public channel, regardless of whether you were even a part of the company at the time, with as convenient of a workflow as Slack has?

There's nothing wrong with IRC if you are trying to solve the problems of IRC. They don't solve the business problem as well as slack does. Slack is Slack because of search and an easy to use client with a universal extension set.
A few points, you need to judge how well they apply to your situation and your relationship with the coworkers:

a) have you discussed the expectations on your code review (and the time it takes)? A clear "take the time you need" or "focus on bits that look critical" might answer that. (Certainly many places would be fine with someone new taking time to understand what's going on, but if you are worried it might be good to get clarification on that)

b) similar, what kind of focus do they expect from code review? E.g. I know places that take stylistic things very seriously, and others don't at all. Stylistic stuff is on one hand more to think about, but also an easy place to show "yes, I'm reviewing this".

c) Asking people to change their workflow is always a bit tricky, but if you think it helps maybe you could ask for more smaller MRs - that makes changes easier to think through properly IMHO.

d) are the changes missing context for you to understand? "I don't get why this is correct, can you please expand the comments/commit message" is IMHO valid feedback.

e) hopefully as you learn more about the structure you can prioritize yourself better, e.g. by recognizing that changes fit established patterns and don't need as much attention.
I don't believe you, but I look forward to you showing proof of this with some links (and if you tried giving it for free, I assume you just open sourced the whole deal, so I look forward to a repo link or the like).
350Z Bursts into Flames
The sad truth is Amiga hardware barely changed from 1985 to 1992. The A500 was nothing more than a cost reduced A1000 - no new features. The A2000 was nothing more than an A1000 with expansion slots. The A2500 was a couple extra boards, not a new model. The A3000, my favorite machine, was effectively a cost reduced A2500, combining the 68030 accelerator board and SCSI onto the motherboard. Again, nothing new.

So after 7 years, all we had were expansion slots and faster CPUs. The OCS -> ECS chipset upgrade was very minor. That's basically it.

Finally, at the end of 1992, the AGA machines (Amiga 1200 and 4000) were released. We finally had upgraded graphics that didn't even keep pace with SuperVGA. The A1200 was also totally gimped with no fast memory and a slow 68020 that was now over 8 years old...
Not sure what question people are answering here...

At ~65,000 words, or 225 pages how are these "short". I think of "short" as finish in one or two sittings. I read slow as hell but even for a speed reader this is not a "short" story.
The Average American Income figures ( before Pandemic) – how do you compare?
I kinda agree with the sentiment in the articles from an AOSP/lineage/cyanogen perspective.

They should definitely embrace the Telegram FOSS fork [1] and OSMAnd~ [2] (which is a superb offline navigation tool btw) and remove all Apps that require the Android 10 firebase hockey-based notifications. [5] and [6]

A lot of apps use this for convenience and because it was _required_ since AOSP 10 but there are ways to work around that requirement with a high priority notification.

I would additionally recommend to use AppWarden [3] and Blokada [4], because both are amazing additions for an Android device.

Firefox for Android, though, is still a nightmare with all the telemetry. The old TOR Browser 9.5 series is based on old Firefox pre-quantum, 10 is based on Firefox post-quantum.

The issue with current Firefox and TOR Browser is that Mozilla decided to include the Adjust-, Firebase- and LeanPlum-SDK which introduce now more user tracking than ever before. You'll even sometimes see different A/B UIs based on your browsing behavior (not kidding) and geolocation, and of course this happens more often with Orbot being used as a Proxy.

(You can verify this via AppWarden if you don't trust me)

[1] https://github.com/Telegram-FOSS-Team/Telegram-FOSS

[2] https://github.com/osmandapp/OsmAnd

[3] https://gitlab.com/AuroraOSS/AppWarden/

[4] https://github.com/blokadaorg

[5] https://github.com/Telegram-FOSS-Team/Telegram-FOSS/blob/mas...

[6] https://developer.android.com/guide/components/activities/ba...
I particularly like the rant on pharmaceuticals companies lack of basic research. My impression has been that medical progression have been slow for quite some time, nice to see that there are some truth to that.

In the end software and tech companies might just eat up the pharmaceutical industry as well. - It's all just code at some level.

The Deepmind team did this with ;

"We trained this system on publicly available data consisting of ~170,000 protein structures from the protein data bank together with large databases containing protein sequences of unknown structure. It uses approximately 128 TPUv3 cores (roughly equivalent to ~100-200 GPUs) run over a few weeks, which is a relatively modest amount of compute in the context of most large state-of-the-art models used in machine learning today."

So it wasn't out of reach for academia, pharmaceuticals, or others with a bit of resources.
It remains unclear whether QM is required to fold proteins accurately. So far classical methods have shown they require far less computer power to get far closer to the right structure.
Killing the free plan seems asinine. What would Slack's brand and standing be if it weren't for the availability and ease of onboarding?
The key thing to me is that everyone on the team should be able to understand what the code is doing. If I am out and a team member can't read my code to troubleshoot a critical issue, I have let my team down. If I change projects and the next programmer can't easily pick up my work, I have let my team down.

Approach it from that perspective. If a "rock star" is coding above someone's head and making sweeping changes, that is a liability. The moment you feel out of your depth, that is the heart of the code review. A line-by-line reading from that point is a waste of your time.

If the 22-year-old junior on my team said to me, "I tried to review your code, but I don't understand this section with the generic functions," that to me would be the value--not whether I followed our guidelines or made some minor mistake. That's an opportunity for me to improve the maintainability of my code and help my teammate improve their knowledge.

You should be able to carry out your code review with this teammate in that way with confidence in my opinion. If you feel like you can't, that seems dysfunctional to me.
This reminds me of AlphaGo and AlphaZero. DeepMind was able to produce a very solid model on their first attempt, at both protein folding and at Go (and Starcraft2 as well). Their second models, however, seemed to blow their first out of the water.

This bodes extremely well for the future of computational biology, I'm very excited thinking about the prospects. If we know how a protein folds, we know its shape, meaning we know which shaped/charged molecules are needed to act as suppressors/enhancers of those proteins.
I forget that Salesforce owns Heroku all the time. Seems like a pretty successful acquisition to me.
Amazon’s cloud chief aims to reset the competitive landscape
I usually use

import ipdb; ipdb.pm()

for quick post mortem debugging, which also allows to see the variables at the moment where the exception was raised (Command locals()).
Is there a scenario where this adds value?
Try making crepes with the bacon grease. They are divine.
There's definitely several ways to ask the question, but IMHO the best answer to an unqualified question is to frame it in terms of what the necessary state to store in a thread context. To that end, the registers boil down to:

* 16 general-purpose registers.

* 16 or 32 vector registers.

* 7 vector mask registers

* 8 x87 floating-point registers, with 8 MMX registers aliased. (To separate or not separate x87/mmx is definitely a challenging question)

* 3 normal status registers: RIP, RFLAGS, MXCSR

* 6 x87 status registers: FSW, FCW, FTP, FDP, FIP, FOP

* 6 segment registers

* 6 debug registers

* Relevant MPX registers (I don't know this ISA extension very well, so I can't count these registers accurately)

These are the registers that I would expect to be able to poke at in a debugger or inspect/modify via something like ucontext_t, and they're going to be found in whatever kernel abstraction you use to save not-currently-running thread information.
Free Modified Car Giveaway (Not Clickbait)
Other advantages over BEAM: Static typing, multiple languages with a WASM target available, live migration of process to the browser.
marketing bullshit
Anyone care to muse about appropriate investment strategies based on the not previously feasible research approaches that might now be possible?

Should we expect to see faster progress in large well capitalized bioscience companies -- or a sudden increase in the viability of smaller biotech and/or biotech startups ...? Are we gonna see top talent fleeing the old biotech companies to start their own ventures with a new belief that the potential for huge reward might suddenly seem achievable?

What kind of companies do we think will be the first that are able to translate this new knowledge into profits?
Living off capital gains is the easiest tax dodge in Germany. You pay ~50% on income, but only ~25% on dividends etc. (and that's before your financial adviser gets creative).
Quite simply I'd like to internalize all externalities so that market forces can determine equilibria. So yes, I think if we could effectively determine provenance, I would like very much to enable that for all things - diseases being the obvious ones, but certainly anything else where externalities exist to some trackable degree (carbon emissions are an obvious one).

My rationale for this case is quite simple. I have very effective protocol around this disease, high risk tolerance, and I want to retain the life I had before (going out, restaurants, clubs, etc.). In exchange, I'm willing to allow you to sue me if I get you sick. I think this will create a freer society, and allow people to find their own position on the risk-benefit curve. It doesn't make sense to subject me to the conditions less-risk-tolerant people want. However, it doesn't make sense for me to subject them non-consensually to conditions I want. A good mechanism to balance these things is a near-continuous universal value measure. A good near-continuous universal value measure is money.

FWIW I've rewritten your question from "why do you feel you are entitled to sue..." to "why do you think it is a good idea for society to permit people to sue..." since I think that's more interesting. The answer to "what gives you the idea that you are entitled to sue" is "nothing, since I do not believe I can right now" which is sort of a boring (though correct) response.

Of course the whole thing is moot. Hard to prove who really caused an infection when community transmission is rampant.
But from what I understand the vaccine does not prevent you from getting the Virus and it's unknown side effects
In a similar vein, my home-city was vying hard to get the Amazon HQ2 to be located in it. The bid was a longshot to begin with, but I was so relieved when Amazon chose not to come to DFW. Sure, I know it would have been great for "The Economy" but terrible for the average Joe and Jane just trying to get a middle class life established here.