skysight-inc/HackerNews huggingface dataset:
> One figure wears a mask resembling a bird with a beak.

Tinfoil time: that one's a fairly common image in petroglyphs on several continents. See also the "Squatter Man".
Yeah, he would have hated "Star Wars", LOL.
Anecdotally I got some great recommendations to gym equipment on Twitter.

I tweeted what was best for small space living and got great responses immediately.
There's something I don't understand about protein shapes. There are tons of software solutions – on the web and offline – to visualize the shape of proteins from their sequence of amino acids. How do these work then, if we don't know how the atoms might be arranged in space?

For example, this[1] is the code for SARS-Cov-2's Spike(S) protein. From what I understand of this page it's pretty short, only ~1,757 proteins (corresponding to ~3,821 bases in RNA).

And here[2] is a visualization of it in 3D. You'll likely recognize the characteristic mushroom shape that's been portrayed in 3D models of SARS-CoV-2 in the media. How does this software work if there's no real way to tell how the protein is arranged?

[1] https://www.ncbi.nlm.nih.gov/nuccore/NC_045512 (search for spike glycoprotein on that page)

[2] https://3dmol.csb.pitt.edu/viewer.html?pdb=6X6P&style=stick&...
To elaborate on this, the white marble statues decorating the Parthenon and Acropolis are believed to have been painted very bright colors in their day. Not a single one of those dazzling pigments survived exposed to the elements after a mere 2500 years.
From GM's perspective they stood to lose nothing and potentially gain. It didn't matter if the guy was running a scam, might as well give him a shot in case he pulls it off since the buy in is so low (some tech they didn't care about). Oh "what about their reputation" you say? The only people who will know or care about this already have their driveways filled with Model 3s and 4runners and turn up their nose at GM. The real buyers don't care. The big banks, the suppliers, the big corporate entities GM has to deal with don't care either since this doesn't affect GM's perceived trustworthiness to d business with.
Or am I misunderstanding something.
Yes.

From the Bisq FAQ:
Security deposits are set to be a percentage of the trade amount—actual percent varies by BTC price volatility, but minimum is 0.006 BTC—but the percent can be adjusted by the offer maker to be as low as 15% or as high as 50%.

0.006 of a Bitcoin is $117.366
>Trevor told Jonny Robb to stop posting about his behavior towards women, and in exchange he would give him $500,000.

IANAL, but how is that not entrapment? Or even if it wasn't entrapment, how is it different than signing a NDA/non-disparagement contract?

>possession of a controlled substance (weed + mushrooms in his car)

okay that's just dumb.
Doesn't reddit automatically strip referral links and put in their own? I thought they started doing that a few years ago as a monetization strategy but I could be wrong.
Vitamin D insufficiency may account for almost 90% of Covid-19 deaths
Personally, when I think of biotech, I think of gene editing, growing organs in a vat, etc. I would tend to put brain-computer interfaces in a different category.

That being said, I think that biotech is not progressing much because there's a lot of regulations slowing down research, and nobody has really demonstrated a "killer app" yet. I think what could happen, is that we will eventually be able to use gene therapy to really effectively kill cancers, and then funding is just going to pour into the field at 50 times the current rate.

There's a lot of other cool things we could do with gene editing, like fixing incurable depression, life extension, fixing genetic diseases, curing irritable bowel syndrome and dangerous allergies, but there's currently not enough funding, and there's not enough excitement, people are too worried about "ethical" implications.

I think it might be similar with brain-computer interfaces. Someone needs to spend a lot of money to get the first version working. It's possible that Elon Musk will win that race with Neuralink. If we can have a brain implant that allows a paraplegic person to move a robot arm, send texts and make themselves dinner... 10 years later you will have disabled people walking with exoskeletons and hackers hooking themselves up to computers. It could all happen within our lifetime. We just need someone to make that first killer demo, then funding pours in, 100 startups pop up overnight, and innovation really takes off.
Plus 32.
The author is talking about representation of data, I'm talking about something different. I'm talking about scoping, grouping, modularity and free variables.

y = 6
f(x) = x + y

y is called a free variable and f is dependent on it. I cannot move f to another place because y will now be undefined. OOP is a more extreme version of this.

class X
y = 6
b = 8
f(x) = x + y

Now f can't even be moved to another place without b. If you want to move f you have to move b as well.

Combinators vs. free variables is the fundamental issue of OOP which this article writer effectively side steps with a unique definition of OOP where the method returns an entirely new object with differently defined methods.

It's ok. It's worth talking about the trade offs of unique definitions of OOP but I think the author needs to mention that this is also not a mainstream definition and therefore sidesteps all the mainstream controversy.
More as a collectable than anything else.
The heat capacity of the plasma is actually fairly low. So while it might take a but of wall material, it would cool very quickly, electrons would get captures, and you are left with a bit of gas at rather low pressure.
This isn't my area, but my understanding is that like most things related to history (especially Indian history), it's complicated. There are a lot of very old antecedents, but the modern caste system probably "originated" with the later Mughals. The British Raj took those scattered, vaguely related systems and codified them into what we recognize today.
I think people still has this belief that power users is still an important target market for Apple. Basing on their hardware decisions and software support, I don't think this is true anymore.
The point is that in chess there's some variance between the opening/tactics/strategy/positional strength of players at the same level, but not _that_ much difference.

To cheat convincingly you have to boost all those facets at the same time, because otherwise you'll just give yourself out. For instance, nobody is extremely sharp at tactics but severely lacking (human-understandable) strategy.

Engines will help you in opening and tactics, but not too much in the positional/strategy game (they make good moves, but oftentimes it is just impossible for humans to understand them without very deep study, meaning they would never be casually played in an online game).

Another example, regarding cheating but only on the openings: even GM's make mistakes during openings. If you play openings at that strength level but then you often lose won endgames it is clear to anybody who knows the game that you are cheating (because opening theory is much wider than the standard endgame theory).

Finally, since you are not at the level you pretend to be whilst cheating, it gets very very complicated for you to know what you can or cannot get away with.
yes good catch, I forgot to mention that. I wanted to highlight that for the average user being able to backup and move messages to a new device easily is a big plus even if its insecure.

I hope in 2021 Signal can improve their new transfer method by allowing transfers between Android devices or even ( albeit far more difficult) android and ios
Is there a image classifier that use my Dropbox, scan all images sort by tag, and save all neural and tag data on folder itself ? That I can use to access all the images ?
It's generally be better for one's sanity to not get instant notifications anyway. But if you need them, you can also get Slack notifications over email. Or maybe you can set up a bridge and use some Matrix client (one less proprietary app on your phone then).
I think these walled gardens show how important distribution is.

Everyone complaints about record labels but artists are still signing onto deals.

With some talent and the right amount of luck (discoverability), unheard of people can float to the top.
The GP derives comfort from exactly that point--at some point, the behemoths calcify, and the incentives that come with size lead to a slower growth, if not outright decline.

This gives the rest of us a chance to one day have our day in the sun. We can deliver solid software, precisely because we are not big. And then, perhaps one day we may have the choice of growing into a bigco ourselves, or staying small.
I'm more bothered by the arbitrary origin of the scale… what's that temperature in Kelvin?
Given that AMD licenses recent tech to Microsoft and Sony, I'd be shocked if they would turn down a reasonable offer to design SOC's for/with Apple.
What?

a) I asked how is it not possible in Java. The Kotlin library is just an example of something I use, it's not relying anything impossible in Java as far as I can tell... like I said reified generics don't change what the calls would look like, just what the implementation looks like

b) What do checked exceptions have using Result? The whole point is you use Result monads in all your code instead of exceptions. When interfacing with legacy code you wrap any exceptions in a Result class as well.
You're definitely right, but it doesn't change that, at least from the inside, the parent comment seems to be accurately describing the cognitive dynamic. I'm married and in my 30s. We aren't planning to have kids, we have no assets, my wife still has student debt (epidemiology is a bad field if you plan to work in the public sector), and with my "good" insurance, I can't afford dental work that I need related to growing up in poverty.

Despite this, we have super comfortable lives, as you say. We've jumped from trailer park, meth country poverty to truly living like we're in the middle class, something I think is way harder to do in other countries. But kids? No. That looks like a ticket right back to where we started.
It'll probably be minor to medium damage to the containment vessel, but the amount of gas actually at that temperature is very small, and will cool down very quickly once it expands and dissipates.
> The user has to somehow know that they have to do this to get the benefit of forward secrecy.

I mean, this is basically true of every feature in every product.
There is a reason why designers, photographers, video editors and influencers are the prioritised. Get them on your side and it's free marketing for you.
> In real world test after test, the M1 Macs are not merely inching past top of the line Intel Macs, they are destroying them. In disbelief people have started asking how on earth this is possible?

I'm getting sick of this. The M1 is an impressive chip for sure, but it's ridiculous to compare them to the Intel chips in last year's MacBooks. Those chips were old, the cooling solution was terrible, and Intel had already fallen way behind AMD for the kinds of tasks you might actually use a MacBook for. The cynic in me thinks Apple intentionally handicapped the 2019 models to make the M1 look as good as possible... and it clearly worked.

Can we please stop comparing apples to oranges (pun intended)?

Like I said, the M1 is impressive - especially in terms of power efficiency - but we should be comparing it to the likes of an Intel Core i7-1185G7 or the imminent AMD Ryzen 7 5800U.
It is true that for these initial protocols, they are only testing becoming symptomatic versus prevention of transmission. That said, all the trials (at least in phase 1/2) are also looking at antibody levels[1][2], which would indicate less likelihood of transmission.

Remember, all these vaccines aren't yet applying for full approval, but an EUA (Emergency Use Authorization). I fully expect that the FDA would want to see data on transmission before full approval; but that is harder to acquire, so it makes sense they wouldn't wait for that specific data.

As someone in the AZD12222 (AstraZeneca/Oxford) trial, I can confirm that they are following all participants for a full 2 years. In this time (versus the ~3 months each Phase 3
trial has run for), there will be much more time to see if these vaccines prevent transmission, not just prevent symptoms.

With all that said, many thousands of live will be saved by getting these vaccines out now, even if they are only partially effective. After all, someone who can't get sick can return to a more normal life, since they won't have issues if they were to get SARS-COV-2 infection later on.

[1] https://biology.mit.edu/undergraduate/current-students/subje... [Lecture 10, with a NIH researcher who worked on the Moderna vaccine]

[2] https://www.thelancet.com/journals/lancet/article/PIIS0140-6... [Phase 2/3 study of AstraZeneca vaccine, figure shows neutralizing antibody levels]
Many people live hundreds and hundreds of miles from the nearest DMV. Other people live in jurisdictions with millions of people and only one DMV office, because the DMV is a state, not municipal agency. Others lack the documentation necessary to obtain an ID by modern standards, because at the time of their birth their state or county didn’t bother documenting births of people of their race.

Voter ID laws may not be inherently racist, but they are designed by racist people to disproportionately impact black Americans.
What about girls? For me, money always was only as important as it helped with the girls.
100M Kelvin
Water used in Mining also has an environmental impact - wet processing of minerals creates "tailings", which is essentially contaminated waste water which then needs to be stored somewhere usually in a dam. A lot of the largest environmental disasters in recent history have been caused by tailings dams.
The game was https://fold.it/ presumably.
Nice! Sharing access is a good idea
Officially my new favorite website!
Not sure about KSTAR specifically, but a lot of these devices use the field both for containment of the plasma and for starting/maintaining the fusion reaction in the first place. If the field fails, the reaction stops.

If it didn't (hypothetically), I imagine it would do some pretty severe damage to the reactor parts specifically. At some point, the vacuum would be broken, air would rush in, and the reaction would _definitely_ stop.

Most of the larger fusors (as far as I'm aware) seem to be refinements of the basic Farnsworth-Hirsch fusor design (https://en.wikipedia.org/wiki/Fusor), which is a relatively simple device. If you have the motivation, you could build one at home with common-ish tools.
Etsy: The Dark Horse of E-commerce
I'm very sorry to read this. I've read Ben Bova's writing most of my life. I met him about 10 years ago at a book signing. He was nice and gracious and we had a long talk, mostly about his Immortality book.

My favorite Bova books are probably "Privateers" and "Test of Fire".
His thinking that the will and advantage of the few (his telecom bros) over the many (your average American with internet) and doing away with net neutrality makes him extremely incompetent in my opinion. He's a civil servant to the interests of the people of the USA not AT&T, Comcast, and Spectrum stock holders.
> we need to build and fail a lot more

inb4 FUD from people who think nuclear power failures have been lethal more than once
Well, that's because 'worth' is ill-defined on its own. The 'worth' of that sandwich could be any of "last clearing price", "current ask", "current bid", or any other metric you choose.

So the sandwich isn't worth a million but it isn't worth any sum because 'worth' isn't a concept on its own.
I would expect that reopenings wouldn't be based on vaccinated percentage, but caseloads, just as they are now. Once more people are vaccinated, however, those will decrease.
ForkAwesome – Pictographic Icons Font
It's happened plenty of times before.
Yes, that's all true, but after even two stages of this you're in the kingdom of the nouns.

Note the argument is not structural, but philosophical. Yes, the two constructs are logically isomorphic, but to get composability with objects you must start twisting your brain in uncomfortable ways. I would concede there might be a minority of folks whose brain truly works like this. For the rest, it must be stockholm syndrome.
Non-rhetorical: So what's the point of this experiment? Seems like harnessing its energy will not be very effective based on how quickly it dissipates
"Please consider this a commitment that I will fund fusion energy for any house in Flint that has water contamination above FDA levels. No kidding."
Entire classes of diseases may become history. Creutzfeldt-Jakob and other prion diseases can now be completely understood. Precision targeting of cancerous cells will become trivial (in theory). Minimal life projects (simplest cell possible) will require less trial and error. In general, it will provide a magnitude level improvement to biotechnology, akin to moving from Aristotelian physics to Newtonian.

Some possibilities: artificial muscles for robots, man-made blood substitutes, designer enzymes to break down plastic and other compounds. Software defined biology, where the pipeline from DNA code to actual protein can now be modeled in silico ahead of time. The biology classes of the future may be less observation of animals and more training in usage of whatever the equivalent of Autodesk for biology will be. Healthcare economics in developing nations will be changed as biochemistry itself may finally become deterministic (to some extent). Orphan drug development price would drop (and if you take into account right to try laws and ignore ethics in favor of progress, then people with rare disease may be cured en masse without bankrupting the health insurance company).
We were only given 3 (or fewer) significant figures.
Yeah, so he's paying 40 cents per. Sounds about what a HP is worth.
They were presented in mine, though New York being the center of Loyalist America probably had something to do with it.
Endpoint Secret Manager
In a lot of disciplines, open book doesn’t help you solve problems all that much.

It might supply some of the pieces required to solve problems, but the ability to remember all of those pieces by rote vs. looking them up is really orthogonal to the ability to apply them to solving a novel problem. Indeed the ability to find the requisite information to solve a problem in a timely manner is an important skill in itself and more accurately represents the real world problem solving one is preparing for.
I hope their programmers are better than their lawyers; the terms of service for their website require you to attest that "you are a physician or other healthcare professional". (https://insight.space/terms)
That's kind of the point.

Compilers existed just fine to do the porting, and solved that problem.

Intel's failure is that they were unable to solve a different problem because that compiler didn't exist, one that went well beyond merely porting.

In other words, "That's what compilers are for." is a perfectly fine attitude when those compilers exist, and a bad attitude when they don't exist. Porting is the former, making VLIW efficient is the latter.
Out of curiosity, which country didn't have servants?
I agree with you. I have lived in SF since 2005. In my opinion, the problem is that the tech workers are not engaged with the city. They are here for the jobs, and resent the city. The high prices chased the old SFers away, the artists and eccentrics who enjoyed and loved SF ... and the influx was such that there was no opportunity to pass along the culture. More people needed to be shown what was fun and groovy about SF, than the existing population had the capacity to do.

What was neat about SF circa 2005-2012 is that folks in general were happy, excited, and proud to be here. Current day tech workers complain a lot, while contributing little (presence, acceptance, consciousness) to help solve anything: viz the comments on this post. Now they dance upon its grave as they decamp to Montana or Ohio, etc. So in a sense part of the problem is just the mood of the place.

If you ever read Jane Jacobs "The Death and Life of Great American Cities" she describes exactly the cycle we are experiencing: a cheap place is colonized by artists and eccentrics, it becomes cool, this attracts mainstream folks, this makes the place hyped & expensive, the people who made it cool move away, it then becomes lame, eventually it decays, is abandoned, and becomes cheap again.

Be zen, this is all part of the normal life of the world. In the fullness of time, SF will have many more boom and bust cycles.
I just tested this on my Linux workstation.

2000 threads does nothing - everything's still responsive, and the process is shown as using 0% of the CPU.

16,000 threads uses ~30% of a core, with a ~136MB RSS. The system still handles it fine, though, and everything stays responsive.

At 20,000 the program panics when spawning threads, with the message "failed to set up alternative stack guard page" due to EWOULDBLOCK. I'm not sure exactly what limit it's hitting, though.
There is no getting around the fact Bitcoin is distributed in a fabulously unequal manner.

The rest of the world is going mint a set of new global elite because they mined a stack a coins when the computational cost was tiny? If crypto dream of having Bitcoin as some global reserve currency is achieved that is what will happen.

To be honest that situation is not far off the inherited wealth of a lot of the super rich families that exist now. But at least you know somewhere along the family tree something worthwhile was achieved. Their claim to wealth is not simply being on the right internet forum in 2010.
I wholeheartedly agree. I was thinking the same thing to myself a few days ago.
I don't think SpaceX came in to play when it was "may or may not work", tech is mostly developed by NASA and others over decades.

SpaceX's value add is eventually providing economies of scale.
If you are interested in the evolution of film, including the silent ones, this course on MIT OCW is a good resource:

https://ocw.mit.edu/courses/literature/21l-011-the-film-expe...

I subscribed to the Criterion Channel after watching the lectures, which has a number of the movies referenced in the course. I developed a new appreciation for Buster Keaton and Charlie Chaplin. There is a lecture on German film:

https://ocw.mit.edu/courses/literature/21l-011-the-film-expe...

Prof. Thorburn doesn't seem to like Metropolis either:

> It's much admired by certain film scholars, although not by me.
But Apple is very big now. They can now afford to not court the "Alpha Geeks" since they already have captured the mainstream market(at least in the US).

You may say that's not true. But just look at their actions and not their marketing speak.
> Nothing about this changes the fact that protein crystallography is a gold-standard method for determining a protein structure.

Yes it does. Protein crystallography is/was the gold-standard. Once this result is verified and accepted by the scientific community as a whole, that changes.
I'm in the AZD1222 (AstraZeneca) trial, and for the next two years, I need to fill out an online symptom questionnaire every single week. They also draw blood at the 6-month and 1-year mark, so presumably could test for antibodies.
100.00027315M Kelvin
Azure Yacht Group – Hybrid boat and catamaran building company
No it's the best time. If it fails, nobody will notice with the rest of the planet burning.
I am going to guess that using 100 year old salt mining methods are cheaper than trying to mine asteroids. Also if asteroid mining were possible, I think gold is going to be first.
but i don't want to update all the packages to latest always though.