skysight-inc/HackerNews huggingface dataset:
this is different for each disease based on how quickly it transmits.

for SARS-COV-2 you need around 70% immunity in the population to achieve herd immunity
Do what everyone else is doing - put up a sign that says "Black Lives Matter".

The issue is big enough where it's OK to use the slogan - everyone will know what you mean.
> The people that printed tether now sell their btc for a profit and can now cover their tether obligations to keep the illusion going that tether is 1:1 backed with usd. They can now repeat the tether printing cycle.

And who is getting scamed here? Who is sitting on the tether at the end of the day?
I've been interested in this, but it's a steep price to pay without a preview of their work - I'm a college student so funds are tight.
I think I read (and I may be wrong) that the costs for the vaccines per dose were roughly as follows:

Moderna: £45,
Pfizer: £20,
Oxford: £3,

The Oxford one is also easier to store and transport.
Like OnStar, it’s sold as a safety feature. You get in an accident and a rep calls you to make sure you’re okay, send a tow truck or what not.
Yes that's all true and we are sleepwalking into being controlled.

Creating a news website without a regular set of themes that show up again and again is very difficult. Any control mechanism will allow some themes and remove others. The best outcome is people knowing what they're signing up for, when they read any given news source.

The old order has fallen apart, I don't know what life their is left outside the metaphysical forces which tie us down.
This is pretty standard due to transport + location costs, isn't it? Gas is close to cheapest in city suburbs.
Dr Fauci stated earlier that he was hoping for 70% efficacy. So these results are still good, not just as good as the 94% seen earlier for Moderna's vaccine.
I doubt they implemented CDC in hardware.
If they have a low-level USB peripheral, all the high-level protocols you want can be implemented in software.
Show HN: Fandom Utils – Fandom useful utilities all together
Nest still doesn't support IFTTT (unless you don't migrate to a Google account)
From AstraZeneca:

> One dosing regimen (n=2,741) showed vaccine efficacy of 90% when AZD1222 was given as a half dose, followed by a full dose at least one month apart, and another dosing regimen (n=8,895) showed 62% efficacy when given as two full doses at least one month apart. The combined analysis from both dosing regimens (n=11,636) resulted in an average efficacy of 70%. All results were statistically significant (p<=0.0001).

Also:

> and no hospitalisations or severe cases of the disease were reported in participants receiving the vaccine.

https://www.astrazeneca.com/media-centre/press-releases/2020...
>RGB simply does not map 1:1 with our biology.

Hate to be picky... but actually it maps rather well to our biology. After we, we see in RGB. what it does map to is our perception. HSL is good for artists as a ‘thinking space’.

The real problem is that in art literature most Colour spaces are expressed as 2 dimensions. So called harmony is discussed most as an attribute of hue, never of a compound of hue, sat and lightness.
Then it's worth noting that it is easier for a person to change which employer they work for than a business owner to change which government creates laws that apply to their business.

I accept, though, that corporations are artificial constructs that exist (ostensibly) to benefit humans, and therefore placing restrictions and duties on corporations is inherently preferable to placing them on humans themselves.
The key point is that if you lower the replication rate-- the number of people each person with the virus goes on to infect-- below 1, the number of active cases exponentially decays to zero.

The business-as-usual replication rate of covid appears to be somewhere around 4-6, meaning that if we have universal vaccination with something like 80% efficacy, the number of active cases will exponentially decay with no other measures taken (social distancing, masks, lockdowns, quarantines etc).
You're misreading what I'm saying; I'm not proposing an alternative law (and have no interest in doing so), merely stating that the criticism of the original article saying that DMCA reform would run into first-amendment issues is invalid. Competent legislators have enough freedom to go in fairly different directions, if they so choose.

The point being: if you want to propose an alternative to the DMCA, worrying about the first amendment at this stage is premature.
I would think so.

First of all bio-polymers is nothing new and revolutionary. The first plastics where bio-polymers like bakelite made from cellulose. The only reason we started making polymers from oil is because it's a rest product from the oil-industry and thus cheap but the inherent properties of polymers are the same whether they come from oil or plants and they typically don't break down in nature. The only positive thing with plant based polymers is that they could to some degree be considered carbon neutral.

But there seems to be a lot of misunderstanding that keeps spreading because we inherently think bio-polymers should be bio-degradable because they are made from organic material. There is one bio-based polymer in particular, PLA that is actually said to be bio-degredable and used in paper cups but this is in industrial facilities and not in nature where the degrading process is at lest 70 years under optimal circumstances.

And there are more problems with polymers then just the fact that they don't brake down in nature. They contain toxic and endocrine disrupting chemicals like BPA.
oh man that looks like a ton of work for not much gain.. Why not use vim mode in pycharm instead of reconstructing an IDE in vim?
When I microwave a TV dinner, I'll pop it out of the tray and into a china dish to microwave.
BASIC is closer to assembly than JavaScript, both in complexity and that you can't implement a JavaScript anywhere as simply as you can implement BASIC
Optimization is always a multiple choice that depends on your concrete process, not only your purpose.
Wow, what a fascinating phenomenon. A weak first dose somehow primes the immune system better than a full one?
It isn't directly an issue of morals. I was speaking to the severity to the individual employee. Opposition to gay marriage is obviously a hugely important issue for a gay person. There is no way to really compromise on a civil rights issue like that. Either people have equal rights or they don't. Someone being excluding from those rights can't accept neutrality as an answer.

Also I want to point out that I specifically called the argument unreasonable and not the people. I meant "unreasonable" as a synonym to illogical. There is no real logical consistency to any arguments that there should be added legal benefits for straight couples that don't apply for gay couples. All the arguments fundamentally come down to some sort of bias against gay people which can be ideological or spiritual but are never based on reason or logic.
Learning to be Free
This vaccine is a viral vector vaccine. Immunity against the vector can be an issue, but this is moderately informed speculation.
Hyperbaric oxygen treatment: reversing aging in human cells
What is the state of the open-source alternatives to Nest+Google ecosystem? Is there some active community doing something similar?
Hn is especially obnoxious by making downvoted posts physically harder to read by lowering the text contrast. Just seems insulting.
This statement seems a big deal:
"There were no hospitalised or severe cases in anyone who received the vaccine"

Is that also true of the Pfizer and Moderna trials?
Are the various trials measuring 'effectiveness' in the same way?
Is there a standard for 'effectiveness' in these Covid-19 trials?

It will take some digging and real effort to compare the risks and benefits of the various vaccines coming to market.
Full title that did not fit: Hyperbaric oxygen treatment: Clinical trial reverses two biological processes associated with aging in human cells
Ah, the minimum effort approach to patting yourself on the back. Note that the least fuel intensive act is to not ride the train or the Hummer, but that would actually be disruptive. The correct answer was to use an electric car powered by solar (because the current zeitgeist doesn’t care about manufacturing). Thanks for playing though, you’ve been cancelled.
1. A legal inequality from 100 years ago. My comments are about the US specifically, no doubt systemic sexism exists in other countries.

2. From your wikipedia link, one of the key arguments against the amendment was that it would imply women could be drafted - "Political scientist Jane Mansbridge in her history of the ERA argues that the draft issue was the single most powerful argument used by Schlafly and the other opponents to defeat ERA".

If you want to show a persuasive (to me) example of systemic sexism, I think you should provide an example that is current and that systemically disadvantages women. If the lack of an ERA does disadvantage women, please explain how.
Apple Provides Instructions to Fix macOS Reinstallation Errors on M1 Macs
Rosetta is designed to work on all x86_64 binaries.
That has nothing to do with purchasing it.
Correct me if I am wrong,
Oxford uses traditional Vaccine design technique (using a weaker virus and adding spikes or something similar) while Biontech(Pfizer) and ModeRNA use MRNA which is completely new technique (messenger RNA).

This is awesome for more than just vaccinations. Traditionally the groups allocating govt funding to science and industries are very risk averse and this could be one more example where taking risks can payoff.
“If something is actually important you’ll hear about it” basically means you have resigned to believe the corporate/government spin on everything.

By the time you “hear about it everywhere” because it’s important, it has already been twisted and distorted, and given the party-line spin.

Which is a valid choice, of course - but you should be aware of that, and — if you care about facts rather than narrative - ignore the stuff when you hear about it as well.
> Warrents arent required for things people give to the police willingly.

I never claimed they were.

> Commerical data is definately being provided to police and other government agencies without warrants.

Obviously that claim is true because someone somewhere has almost certainly done so at some point. However, it is a misrepresentation of the overall situation. The vast majority of large tech companies have public policies clearly stating that they require a warrant or subpoena in order to hand over data. Moreover, court records would appear to indicate that this really is the case.

Many of your comments on this article contain non sequiturs and false equivalencies. Honestly, you don't appear to be engaging in this discussion in good faith.
The disease will 'die out' (in quotes because it will not actually) if there are not enough targets that are susceptible to it.

People infected by SARS-Cov2 seem to infect two to six other people [0]. Reduce this number by 90% and we are well below one infection per infected, so it is not sustained. This assumes that everyone would be vaccinated.

Currently we are doing something similar: each measure like wearing a mask, social distancing, meeting fewer people, ventilating rooms, finding infected people before they can infect someone else ("contact tracing") contributes to reducing the number of follow-up infections a bit. (This is why "but masks do not really work" is an ill-informed argument. They do not have to because they are meant to be used together with other measures to achieve reduction in spread)

A vaccine will protect us passively instead of requiring us to actively following these measures and will therefore be a lot more convenient.

[0] https://en.wikipedia.org/wiki/Basic_reproduction_number
> People don’t change their opinions on the internet, so I’m not going to change your mind. This just such an upset tingly misguided stance it’s hard to even brush it off.

I would say the exact same thing regarding your misguided claim that refusal to censor content amounts to endorsement of it.

> I’m unsure what the negative side effect of suggesting opposition to harmful views, but that’s on you I guess.

Where did I write that there are negative side effects of removing content? All I wanted to dispel is the false claim that lack of censorship is a political stance.

> I just ask, how do you think Facebook’s stance (the same as yours) is working out?

Where do you get the idea that Facebook doesn't remove hate speech? Their content policies are easily found via Google: https://m.facebook.com/communitystandards/hate_speech
This depends on the r0 of the virus, an r0 of 2 means a 50% effective vaccine (and 100% vaccinated pop) will defeat the virus. With measles and a r0 of 18, youd need an effectiveness of 95%. Considering not everyone can or will take a vaccine, the effectiveness needs to be higher than this.

Covid is apparently around 3, and if you can vaccinate 90% of the population then an effectiveness of 75% would be the minimum you could get away with.
My solution saves all 60 seconds. I just use my coffee cup for water and never wash it. I wish I was joking.
And my personal experience is that some percentage of my comments are downvoted immediately and then upvoted to neutral -- as was the case here.

I imagine if you interviewed all 5 million visitors you would get about 5 million different experiences.

(That's not to dismiss your experience at all.)
MacPorts handles multiple architectures a bit better. Of course the usual "this software doesn't compile on ARM" issues are still there.
The new NHSX RiskScore algorithm for Track and Trace
There's no solution, only tradeoffs.
I had set up disabled fingerprinting, disabled fingerprinting via WebGL, website containers, a whole bunch of other stuff I cannot remember the name of in the Firefox preference list (you'll see why) in an effort to maximise browsing privacy and the result was I spent probably 30 minutes a day filling in reCaptchas; probably 2 or 3 panels per form -- and the ultra annoying slowly-fade-out kind.

hCaptcha was a lot less annoying for websites that used it but the end result was still a grotesque addition of friction to my browsing experience. I ended up resetting Firefox back to the defaults to un-set all those options I made a list of.

That's not a comment on Firefox of course; the sad state of the web currently is that in order to prove we're not a bot we seemingly have to give up our privacy (via relentless fingerprinting) OR your time (through hugely wasteful reCaptcha, and to a lesser extent hCaptcha fills).
I used SPI to generate analog video signal (with extra hardware, of course).
You are not the only one to notice this... Upvotes in the afternoon, downvotes in the night.
> Lately I have been looking into how museums put together exhibits and how to integrate some of their approaches into web or print publishing.

That is a fascinating approach. Do you have any examples?
Was looking at your username while reading, trying figure out which person from my org you are though we're in different industries. The similarities are uncanny; company size, leadership issues, ops person leaving, which of course is disturbing but makes me feel less crazy.
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I think I'm going to manually build things from source until Homebrew officially supports M1 and Big Sur. I don't want to deal with any sort of migration / funky re-install, personally.
> How does the acquisition change this?

We don't know, as there no explanation provided to LDraw.org Team yet.[0]

[0] https://news.ycombinator.com/item?id=25159556#25178143
> If the people really thought Congress was the cause of their anger, they could just vote them all out; doesn't take a genius to figure that out. Yet most people stay in Congress.

A large part of the cause is single-issue voters, especially abortion and gun control. Many people vote R simply because they are so hellbent on turning back abortion rights or keeping the right to buy guns in supermarkets and vice versa. And the parties know and exploit that - Bush, Obama and Trump had times with supermajorities in which they could have ended the respective issues permanently, but they didn't.

The result is a dysfunctional Congress whose members are not held accountable by their voters no matter what they do, and a subsequently disappointed public.

And the same mechanic also applies to the Presidency elections. A lot of people only voted Biden because they wanted to get rid of Trump, and one might say that many people voted Trump in '16 to prevent Clinton who's as Establishment as it can be.
What Apple claims to have done and what Apple actually does are two very different things. Apple has reached out to some projects with various levels of support, but it's not like they just dropped by all of those projects with patches on the day of WWDC.
We Kinda Bypassed Firebase's Paywall: Here's How
Since my late 40s: Learned how to sing opera and pop. Learned sax, flute, trumpet, violin. Learned how to write songs. Started a farm.

Musical instruments were mostly self-taught. Singing required a teacher. Main source of knowledge is web research and YouTube videos.
Serverless functions for .NET are worlds better on AWS and Google Cloud than on Azure, despite .NET and Azure being both owned by Microsoft, or as some people like myself would say, because both are owned by Microsoft.

Microsoft has really messed up Azure Functions. Every time I open the project it breaks because things have changed without me doing anything and then I have to spend an hour figuring out what hidden dependencies the Azure Functions runtime has which I must reference myself before my project compiles again.

I got so annoyed with it that I learned Go in order to use Google Cloud Functions before you could run .NET on them and ironically I have done a lot more Go and increasingly less .NET since then.
If something isn't actionable then is it worth taking up your attention? I agree with you that some news is worth consuming but that's only because I occasionally discuss it with friends.
Increase serious news consumption.

Read multiple sources, keep yourself on top of things, then sensationalized headlines won't stir your emotions as much.
The first language I learned was machine code. Just saying. And I was in no way programmer. I was just a scientist trying to get some digestible data from the device used in my experiments. As the time went by I got Assembly, C, Turbo Pascal etc. I knew about basic but have never used it.
So how is you watching the news going to solve all these last things that you mention? I also don't watch the news. Do you really think we don't know those things are happening?

News is entertainment. If you really want to get smarter, read books from people who are experts in their field.

Edit: if you do want to read a book, start with "Trust me, I'm lying". It will give you a whole new perspective on news reporting.
Google claims that the smallpox vaccine was somewhere between 90-97% effective (they didnt do fully controlled studies back in the day)

Keep in mind, that controlling covid is a giant win. We don't need to eradicate it, just get things under control.
This pandemic has really done a lot to reveal the information bubbles we all live in. Case in point: discussion about indoor v.s. outdoor activity risk was everywhere I looked back in April/May, whereas the author makes it clear that wasn't the case for them.

Do we have any resources which are aimed at helping people inform themselves of the risks associated with some choice they need to make? For example, sufficient information in just three areas could have made every relevant personal choice I've faced since March clear cut:

- Risks (death, hospitalization, long-term side-effects) _by demographic_.

- % chance of transmission for various common interactions (passing someone on the sidewalk, stopping to chat with someone on the sidewalk, grocery shopping, eating/drinking indoors/outdoors, etc).

- % spread by asymptomatic carriers v.s. symptomatic carriers.

Caveats abound, but I bet a skilled designer could find a way to present this information in an honest way which takes < 15 minutes to digest.
No, it is just casual word choice. The audience here, being mostly compsci oriented, likely consider metrics like happiness or fulfillment incalculable, when it is more precise to label them as latent as opposed to observable variables.
There were no hospitalisations or severe incidents for either the Pfizer and Moderna trials were was related to the vaccine.

And it's pretty easy to compare the vaccines. It will mostly come down to price, ease of manufacture and ease of distribution i.e. temperature. Given that for the 3 viruses all have no risks associated with their use.
Ah, yes. the "Casio" ... the monobloc of watches.
> I’ve owned several Lexi in my time.

I went into a rabbit hole trying to find out the plural of Lexus. According to Toyota it's Lexus[1]. Lexi is another option, but apparently the brand name is not derived from the Latin term, so some lean towards Lexuses[2].

[1]: https://jalopnik.com/breaking-minds-and-spirits-everywhere-l...

[2]: https://www.grammarphobia.com/blog/2012/03/lexus.html
Is this the sort of Vaccine that protects against infection or against the disease?
"There were no hospitalised or severe cases in anyone who received the vaccine"

Does anyone know if there's data for this and the other vaccines, whether any of those that still end up infected under the trials have had any of the secondary symptoms such as missing sense of smell, reduced cognitive function, reduced bio-motor functions, cardiac damage and so on? Not dying from a lung infection is obviously the most important, but some of the other organ damage that corona-virus can cause is pretty scary too, and I'd like to know whether the vaccines seem to prevent this too.
This is how I cut down my news consumption.

I switched from reading a lot of news sites most days to picking the couple sites that I like the best and mostly only reading those. And then I read a few of the truly interesting-seeming articles that bubble up on places like this here website, etc.

Pre-internet, I would only buy one newspaper, and occasionally pick up a second when I was out if there was something eye-catching. I would also occasionally buy a magazine or two at the bookshop once or twice per month. I have tried to emulate this method again with the web, and it seems to be working.

I was never a person who would read every available newspaper and magazine before, so figured maybe I should not do the same online.

I am much happier not to face the firehose anymore.
One thing that isn't obvious to me is exactly how `n` is defined, and how that relates to how many people of that `n` were infected by covid during the trial. E.g. maybe n=2,741 people were vaccinated following the first dosing protocol, but perhaps only a small fraction were infected with covid. So the actual sample sizes being used to estimate the efficacy of each dosing protocol may be smaller.
> One dose of MMR vaccine is 93% effective against measles, 78% effective against mumps, and 97% effective against rubella. Two doses of MMR vaccine are 97% effective against measles and 88% effective against mumps. MMR is an attenuated (weakened) live virus vaccine.

From:

https://www.cdc.gov/vaccines/vpd/mmr/public/index.html#:~:te....