skysight-inc/HackerNews huggingface dataset:
Since telomeres are a ttl to protect against transcription errors accumulating and leading to cancer, will this actually reduce aging, or just shift the cause of death towards cancer?
I'm very bearish that the whole "work from home" indefinitely will survive post pandemic.

Everyone seems to take company statements at 100% face value and that they won't change.

I expect many of these companies to do a 180 reversal of policies eventually.There will be some discord and grievances but will eventually drown out.

There may be lingering affects of the situation though as a more willingness to allow 1-2 days from home but not 100%.
I would have loved to see them buying Wasabi instead of building their own infrastructure, and becoming the biggest client of Wasabi at the same time.
I can see in Seattle the restaurants that went full covid seem to be doing well. ie. they converted their front door to a sales point and just gave up on trying to make indoor dining work.
No, you bring up a great question. This kind of vaccine trial is not designed to provide that information, unfortunately. The goal of this study is to show that the vaccine is at least 30% effective (defined by Vaccine Efficacy (VE) in the Pfizer protocol), with a soft goal of hitting a VE of 50%. We don't know anything about what the total population of _possible_ infections in either arm would be.

That said, if we assume that there are in total 170 cases (which is true at this point in time but will change), and that there are 162 cases in the control group and 8 cases in the vaccine group, we can construct a posterior of the VE. Here's an older posterior (done with data from the press releases in the first IA a few days ago) http://blog.fellstat.com/?p=468 that graphs this posterior. There is some uncertainty, but as you can see results are still promising. That said we just don't know how case counts will change, and while it will be fascinating to watch the results change over time, these sorts of tests are just about getting enough data to mark a vaccine as effective, not about trying to extrapolate any larger effect.
Doxer is doxed-Proud Boys member gets doxed by metadata in uploaded dox archive
As someone that's had back pain my entire adult life, not everyone has the same constitution. Understanding, of course, that not all pain is 'the same'. My level of tolerance is likely because I understand the /significant/ risks of addiction. I'd rather not be in pain, obviously, but not at the risk of being a junkie.

I definitely get the impression that a lot of people sucked into pain med addiction are not the sort that have had a lot of previous experience with pain. Making it doubly irresponsible to prescribe such highly addictive medications for them.
Dropbox is in a relatively specific situation wherein their cloud costs would be extremely high (storage, bandwidth) and their in-house technical skills are probably quite good.
I've seen this explanation coming up quite often in discussions around Qualcomm or other similarly sized players: you have to be ordering (very) large numbers to be able to get their attention.
Documentation is provided under NDAs I hear, and if you'd let's say, decide to buy a small(er) number of boards off the grey market (from one of their direct customers), you'd still have the problem of lack of support (firmware/code, docs, etc).
I think the author does a good job of looking at some of the practical aspects of IQ data but I see the question of "Why IQ" quite differently.

When I started with SDR and wrote some Fourier Transform code I wanted to know why if I fed it a sine wave at frequency X, I got two peaks in the transform. Experts said, "Well that is because you have a real signal only, if you add the quadrature component you'll see just one peak." Which is true, if you do that you see one peak, but WHY was my question.

The answer to that question was that there is a difference between discrete mathematics and continuous mathematics. And more specifically, when you operate using discrete mathematics, you need to understand both the slope and the magnitude of the the function you are working with.

A discrete version of sin(ωt) (where ω = 2πf) that is "real only" as some would say, has zero values in the quadrature side. That happens when the signal is the sum of two signals that are the complex conjugate of each other (their quadrature (or imaginary) parts differ only in sign). The discrete Fourier transform correctly picks up both of those signals and identifies them as +f and -f.
> actually, we didn't find out until she was almost 2

I'm curious about this. I didn't realize that the condition could go undiagnosed long after birth!
A market where expected returns are 1, I. e. the implied probabilities sum to 100%
Raising capital in the midst of Covid – free webinar
My parents were manipulated into having prenatal disability tests because of my mom's low amniotic fluid during my sister's pregnancy. Tests came back positive and the doctors recommended abortion. My parents were horrified, being pro-life. They endured a traumatic next few months and a premature delivery. That was 1989. My sister was fine but it left my parents with enduring resentment of doctors to this day.

My abortion "policy" has been that it should be illegal to knowingly put an unborn fetus in jeopardy (unless the mother's life is at risk of course) as soon as the pregnancy is known beyond reasonable doubt. I can't imagine any other policy that doesn't dance with eugenics.

I think that the government's prerogative should be facilitating adoption for the baby and mitigating the "unavoidable" inequity to the mother biology has put upon her.

I understand many disagree with the above, I only ask that you keep an open mind as I also try to do about one of the trickiest moral quandaries in the present age.
The Bay Bridge on the east is definitely a choke point. San Leandro is closer and could take almost an hour driving. Hayward could take an hour but you also have the option of crossing the San Mateo bridge further south and driving up 101, especially if your workplace is closer to the 101 exits on the south side. Ultimately public transport on BART is likely going to be the faster option, since it’s 25-30 mins once you’re on the train.
The weakness of non-violent communication is that it's easy to over-use or use in an inappropriate context, so that you no longer seem genuine. Even if the other person doesn't know about NVC, it becomes painfully obvious that you're doing something different and not communicating normally.

Essentially, you can end up sounding like an inexperienced psychologist or an eliza bot. The uncanny valley of communication. Reactions to that uncanny valley can be severely negative, even worse than the problem you were using NVC to try to solve.
Have a plan and stick to it! Sounds good!

Good points regarding the build up, thanks for the response
> (only very talented and motivated people can pass through these processes and succeed, therefore you're selecting from an inherently more dedicated and energetic candidate pool)

Unfortunately having interviewed a bunch of folks from these programs, I find that to be false the vast majority of the time, from this program especially. I've interviewed probably 5-6 LS folks and over 10 folks from a large program in NYC (you can guess which one) and every time the program has given them an incredibly oversold sense of skill level. They were unequivocally not prepared for the job they were interviewing for but were adamant that they were. I'm guessing they're given interview coaching where they're coached to guide the interviewer towards things that are positive for them (projects they did in the program for example) and away from things that they're not prepared for (such as questions actually relevant to the position). I had one candidate straight up tell me that they were more senior than our senior developers because they spent a year or whatever "living and breathing this stuff everyday, all day" whereas our senior devs wasted their time at college and probably have the same amount of "real practical experience" as this program grad did even though they'd been working there for 3-5 years. Maybe that's gotten better over the past couple of years since I've interviewed regularly, but for a while it was a huge problem where they were ill prepared and then had this massive entitlement about it. I'm guessing that's how the programs were sold to them: finish it and you'll waltz into a six figure job.

That's not universal in these bootcamps/programs, though. I've interviewed a few Turing School folks that are awesome. I've interviewed folks from several smaller programs from all over whose names escape me (a Seattle-based one, one in the midwest...can't remember others) that have been fantastic.

I just _wish_ all of these programs were great at preparing folks and self-filtering on the backside, but unfortunately, I think many of them take their money (or hold out their hand when/if they get hired), pass the people through no matter what, and fill their heads with the idea that they're now prepared and deserve a job.
We used ListenNotes a while back in a web based podcast player and have only good things to say about the API. It's reasonably priced, much easier to deal with than Apple's API and email support is speedy!
I love how simple and effective this is.

I'm also building a web-based literate programming environment called Starboard[1] that's probably a hundred times the amount of code (but then it has additional features such as top-level await, plugin, and Python support).

Consider supporting lit-html[2] literals instead of strings for HTML output, it works really well in notebook environments.

One more thing you can consider: a esm tagged literal that uses import(<data url of the code>), you can then use ES Module imports to dynamically load code. Here's a blog post about that approach [3]

[1]: https://starboard.gg
[2]: https://lit-html.polymer-project.org/
[3]: https://2ality.com/2019/10/eval-via-import.html
> It's giving yourself a pass for risky behavior (bars, indoor dining)

Assuming that all indoor dining is created equal is the kind of black-and-white thinking I'm referring to. Look at how detailed the CDC guidance for restaurants is:

https://www.cdc.gov/coronavirus/2019-ncov/community/organiza...

This is not business as usual.

Also, the way restaurants are patronized in Seattle is different from Central Washington, at least that I have witnessed. In Seattle, I never see crowds of people clustered together, but I have elsewhere.

> The hicks aren't sick because they won't wear their masks.

I haven't characterized anyone a hick, but these people are spreading COVID more because they are not following the guidance:

https://www.seattletimes.com/seattle-news/health/17-cases-tw...

> they're doing the same exact thing as you, just more of it.

I don't know why it's necessary to clarify this, but yes, doing a more of a thing that carries non-zero risk is riskier. No one is arguing that Seattlites are at zero risk. Again, black-and-white thinking. The claim is that the way people in Seattle follow the guidelines has a lower total risk than the behavior of people elsewhere.

> It hardly matters that your tables are spread out, or that you wore your mask while waiting for your reservation.

According to the CDC it does.

> And I don't see why you should attack people for not wanting to make sacrifices that you yourself refused to.

I haven't stepped foot inside any building without wearing a mask the entire time since February. I haven't gone to a restaurant or bar (indoors or outdoors) at all. To the best of my recollection, I can count the number of buildings I've been inside on one hand.

The most recent restrictions in Washington don't affect me at all because I never loosened my behavior after the first wave in April. I'm going well above and beyond what's necessary in order to reduce not just my risk but that of the people I come into contact with.

Meanwhile, jackasses are throwing parties and protesting wearing masks and making it worse for everyone.
Ask HN: Best bang-for-the-buck marketing for consulting?
If you have a marketing budget of <100k to grow a consulting company, which avenues do you think are worth pursuing, bang-for-the-buck wise?
'killed'. Abortion is not killing.

Our society defines it as okay. You apparently don't agree with this but you are not the majority here.

No human aborts a fetus for fun.

My wife and i lost our 'fetus' on the 3 month mark. There have been a lot of thoughts about this experience and lots of emotions. And i would probably abort a fetus with Down Syndrom.

No one is doing an abortion easy. It is never easy for whatever reason and its not your place to criticize it when its not your responsibility.

You have to understand one thing: People are able to seperate the wish of not having a kid with down syndrom from other human beings who have down syndrom.
I'd argue the equities are trading so high is preciesly because of the action the government is taking. By lowering interest rates and offering low interest loans in an attempt to prevent deflation the fed has pushed a ton of money into the economy with the result that deflation is increasing. Because of that people have to put their money in something that will increase in value as inflation increases, the result being that tons of money is being pumped into equities which further drives up the price making them more attractive, because the government is pumping more money into the economy to prevent deflation.

This pandemic to me shows the fundemental problem with a lot of the fancy economic theories we've been living off of and the parasitic "financial engineers" fundamental failing. You can play all the games you want with numbers and spreadsheets to make it look like there is more money than there actually is, but you can't magically change the amount of stuff their is to buy. As such it doesn't matter what measure you use or what KPI you look at for the economy, if there isn't enough crap being produced for people to buy it at a reasonable price there isn't enough crap to buy, and telling people the economy is doing great when I can't afford a roast for dinner doesn't mean jack to me or anyone else.
Why is this guy relevant ?. For all i am aware of is he is ardent supporter of the caste system.
I also have problems with 5700XT. I can't play some games without putting them at very low quality, although the specs of my machine are well within the recommended range. My computer randomly restarts if I am not at low settings. I have suspected overheating, but I have done what I can to fix it bar getting liquid cooling and I still have the issue. Very odd stuff. If anyone has suggestions, please let me know.
I own a business and refuse to list on Google because I'm concerned they use similar tactics that I'm not aware of yet.
Well then ... the fun question is, I guess, who _did_ start the crazy, anti-drug systems we have now? The next time I remember hearing about insanity in prison sentences for drugs was during the Clinton administration. Did it start then? Or was it before then, as well?
That's not what cynicism means.
I dunno it’s more about the principle of not fixing the product. I think software teams would benefit greatly by setting principles that they follow instead of justifying everything by revenue.

Not saying you support the revenue-only model btw :)
A lot of interest in hardware encoders collapsed with Ryzen's release in 2017. Software encoding is superior quality and latency to NVENC, and I've been using 8-thread encoding for Steam streaming since then (April '17) never to look back.

If you don't have or want to use the CPU grunt for that, Intel Quick Sync isn't bad and a good pair with a Radeon like the 6000 series. If you want hardware encoding, Intel CPU + AMD GPU is a great pair, as is AMD CPU + Nvidia GPU. Otherwise anything works well with sufficient core count, can go AMD/Intel CPU + AMD GPU.
For $25K, you can publish climate denial in The Washington Post
Even using the term "Woke Politics" is a giveaway.. I Hope your therapist helps you.
It makes a sphericalcap reflector and shields from radio from the Earth and Sun. You may get something similar by putting a satellite in earth syncro orbit on the dark side of the moon.

https://www.nasa.gov/directorates/spacetech/niac/2020_Phase_...
> My biggest question is whether cloud providers could achieve a scale where they are able to offer the most optimal infrastructure costs for specific businesses.

IMO, this has happened. AWS GovCloud. Since the USGov has near unlimited spending power, it's better for integrators to just pass the costs along. Compared to certifying your own infrastructure, this will probably be much cheaper for most everybody.
Bolt brings Single Click Checkout to 50 major household name brands
They "don't need to understand them", they need to hire people that do..
> it's clear that they realized the ram would be too large to fit under an IHS

This is exactly the same design they used in the A12X and A12Z ( see: https://en.wikipedia.org/wiki/Apple_A12X )

They clearly do have room for a larger IHS that covers the RAM too, but either this makes manufacturing cheaper since they didn't have to change anything from the previous rev or there's actually a real benefit to not dumping excess core heat directly into the RAM (seems more likely). Sinking heat is great, but only if the temperature differential points away from what you're trying to cool.
In what jurisdiction is your wife's business?

If the pattern is that predictable, I'm curious if you could gather enough data to successfully sue Yelp for defamation?
Please don't use HN for market research.
Not locked at all[1]. The rM2 is not quite as known as the rM1, but it seems to still be just as open if you have the right hardware to tell it to get into recovery mode[2]

[1] https://github.com/ddvk/remarkable-uuuflash
[2] https://github.com/ddvk/remarkable2-recovery
> For a healthy young adult, what are the potential long term side effects of covid?

From an overall risk/reward perspective, I would include the risk of subsequently infecting your parents, grandparents or other vulnerable/high-risk family/friends with severe disease as a 'potential long term side effect' of covid in a young/low-risk individual.
World's last known white giraffe gets GPS tracking device
I tried out the "HTTPS Everywhere" Firefox extension but found it cause me more trouble than it was worth, then found "HTTPS By Default" which suits my use much better. It automatically requests all awesomebar requests to https:// by default; one can manually use http:// to bypass it.
> We have some neighbors who are not too well off that homeschool their kids

This is exactly the type of situation ttul seems unaware of. The "only rich white people homeschool" trope is a myth from people who are unfamiliar with the much more complex reality of the situation.
The thing here is that master has meanings that exist outside of the context of master/slave. Yes, slavery is wrong, and hopefully everyone agrees, but there are no slaves in GitHub. There are no slaves when it comes to master records. Erasing the word master from our language isn't about healing, it's more akin to forgetting or denying the past, and everything that could remotely be construed as having a connection with things we shall not speak of.

As for male and female connectors... It seems like an apt analogy, no? And uh, when it comes to male and female connectors, they are both equal, they both play a part, neither is better than the other.
The job of leadership is to make the company succeed. The value of the company is a simple (but effective) "Key Result" metric that's used to evaluate how well they're doing their job (no matter how many others are also contributing).
There's a lot of negativity on this thread. It is understandable when you cynically look at this as just a PR move that will cost them less in the long run if it helps with current and future antitrust investigations.

But what a lot of folks are missing is how much this will help indie-developers and small businesses that want to pay themselves and their employees better and more easily put food on the table.

So while we can still be critical of the current app store limitations and costs - let's still celebrate a move in the right direction and something that is going to enable a lot of people to live better lives.
Try it and see ;-)
This other comment throws up an interesting twist on that:

https://news.ycombinator.com/item?id=25140048

Once we are talking about counterfactuals, that is things like "would haves" about people who don't exist but could have, it opens the door to considering other people who don't exist but could have.

Under the assumption that a family who proceeds with the Downs foetus to birth has fewer children afterwards, ought we not to consider the later children who might not exist as part of this moral equation too?

What if a family who proceeds with the Downs foetus to birth is likely to have multiple fewer children after than they would have had?

Some people born with disabilities might disagree - and have every right to disagree - and see the action of abortion as a judgement against their own existence. But in doing so, are they not identifying themselves more with the counterfactual Downs foetus than with the counterfactual non-Downs foetus?

If so, does that not suggest people who think that way identify themselves with the disability to some degree ("In that world I would have been aborted"), rather than identifying themselves as people independent of a physical characteristic ("In that world I would have been guaranteed my body would not have this disability")?
There is a difference between feeling anxious and going from high to normal. If you've suffered from anxiety, the difference is pretty clear. This isn't what they're describing.
In this context, I think they mean, believe that the published data is true. You don't have to believe in science itself, but you do have to trust scientists when they report data (you can check the conclusions yourself, but you can't check if the data was accurately reported, if the published protocol was followed etc).

That said, I believe the legal repercussions of lying about these studies will be too high to stomach, so I do trust the companies to be truthful here. That doesn't mean that it is irrational to choose not to trust them.
Fast C API in V8
Yes, similar systems are also in place for eggs and poultry. And yes in all cases there are exemptions in place for very small farms, but not enough to make much of a difference.

"Alternative" products like duck eggs, water buffalo or goat's milk, etc. do not count, so there is some room for market diversification there, I guess.

It has the net effect of keeping dairy prices at what's seen as an acceptable stable level that also keeps dairy farmer's in business, at the expense of diversity in the marketplace and access to new farmers.
Regarding corporate contributions:

Often the corporations take the route of least resistance - employing dispensable workers who don't live in countries they're mapping [1], and aren't given proper training.
It seems that southeast Asia (e.g. Thailand) is the major place for such dubious mapping efforts. [2]

There's also a minor conflict of authority: paid mappers (like all mappers) should defer to the community, but they have a manager who they answer to.

In my opinion not everyone has the skills to contribute, and at least if they're volunteers you can tell them (politely) to fuck off and be more likely to succeed with it (and not be outnumbered by the army of corporate drones).

On-the-ground knowledge is the OSM's gold standard. With megacorps in question routinely spending billions on frivolous stuff, they should have instead equipped the local OSM communities with gear to take 360 photos and GPS loggers to enable those on the ground to survey their local areas.

[1] https://wiki.openstreetmap.org/wiki/Armchair_mapping

[2] https://forum.openstreetmap.org/viewforum.php?id=46 (AFAIR many of people posting here are Western immigrants to Thailand, so take correction for that).