skysight-inc/HackerNews huggingface dataset:
mRNA vaccines are faster to develop, despite being newer technology.

This video explains the basics and has a list of citations in the description: https://youtu.be/S1l6BchEoZM
It's you. Vaccine development has been going on for more than a century and got extremely safe. Do you really think you just found a flaw in their process? Yes they still need to be validated by the FDA, being peer reviewed, etc but this process is already started and continuing.
"For 99.999% of you, restrictions will not apply"

This is simply not true. The restriction applies to 100% of everyone using the software under the license.

If an alternative service provider can't legally host the service for me, I am restricted from selecting an alternative vendor if my needs converge from the available vendors offerings.

Further, it still isn't open source.
Higher Levels of Common Knowledge
Just like serverless still has servers, this can be reasonably called dbless :)
I haven't looked it up, but the trial will certainly be randomized.
Randomized trials and statistics solve this problem.
Redsift/Redbpf
It is sad that you have to defend yourself by saying “I’m not anti-vax”. Anti-vaxxers are rightly criticized for denying the overwhelming decades of evidence that the standard repertoire of vaccines is safe.

That’s totally different than questioning new, unproven vaccines, especially when no vaccine of the same type has ever been widely deployed. There are very legitimate concerns about genetic vaccines. And for vast swaths of the population, getting covid might be less risky than getting this vaccine.
So, is it easy to set this up using a phone when you get to a hotel, for example? Do you simply select the hotel wifi to use?
AuthPass – Free and Open Source password manager
Yes, Moderna said it expected the vaccine could be shipped and stored for up to six months at minus 20C

It can even remain stable once thawed for 30 days if refrigerated at between 2C and 8C

This is much much easier to transport/manage compared to the Pfizer vaccine (store at -75, survive only 5 days after thaw in normal fridge)
Maybe a stupid question: Is this the standard measurement of effectiveness? I.e. you give the control group a dummy vaccine, the test group the real vaccine, and you just wait for them to be infected? Why not test for antibody development?
IQ test is bullshit and has been debunked a number of times.

Nowadays anyone bragging about their IQ should be considered a moron and left talking to themselves.

For example: https://www.youtube.com/watch?v=W3oUqKUx2o0 (first thing that came off my head)
https://www.forbes.com/sites/williamhaseltine/2020/09/23/cov...
I'm hoping this is sarcasm, because "revealed preferences" are bunk. Let me propose alternative conclusion and corollary:

Conclusion: they don't dislike it to the point of actually closing the account. Possible factor: everyone they know uses Facebook, so they're hostages of their social network - the so called network effect.

Corollary: they don't really know what Facebook is doing, nor do they have time/energy to care, but if they did, they wouldn't be able to act on it - see point about network effects.
Yes its bias becuase it actually trying to measure the harm on lockdown and comparing the harm. It bias towards trying to achieve the better outcome.

Not all experts even try to measure the lockdown harm.

A good portion of the covid death number being reported is not caused by covid itself so you see the inflated number. The death toll maybe 'high' but it worse compared to the harm of lockdown.
A major reason that this happened so fast is due the US government’s operation warp speed program.

Moderna worked with NIAID on this vaccine closely, and the us gov funded it without regard for if it actually worked or not.

So it’s funding...but it seems extremely unlikely that we would fund most other diseases this way. The way warp speed works is that the federal government funds the vaccine even if it doesn’t work. This allows the drug maker to work faster because they don’t have to worry about losing billions of dollars on a vaccine that does nothing. The federal government eats the risk.

It’s was a really good strategy for the vaccine development and I think the federal team deserves a lot of credit for where we are with the vaccines.
Data Export, or Die
> with vastly larger resources

In a limited US-centric look, it seems like the resources are at about the same level, with funding for cancer at ~$5.6 billion for the NCI[0], and ~3.6 billion for COVID19[1] (in June, not sure if more funding has been approved since).

Not sure what metric you want to consider for cancer survival, but the rough trend in 5-year cancer survival seems to be in the ballpark of improving between 0.25-1% yearly (until 2013)[2].

[0]: https://www.cancer.gov/about-nci/budget/fact-book/data/resea...

[1]: https://www.sciencemag.org/news/2020/06/nih-grapples-researc...

[2]: https://ourworldindata.org/grapher/five-year-cancer-survival...
I don't believe the IME has anything to do with DRM. That would be TPM.
Factorio Raytracer
I think part of the issue with Linux for a casual user can be perfectly illustrated in this HN thread. The comments are filled with endless recommendations for different packages that do the same thing. Choice is great and part of the Linux charm, but for the average user keeping up with it all is overwhelming and simply not worth it.
So it seems that the dealbreaker was that one of tests that downloaded copyrighted material (see the last commit [1]). Seems like a reasonable thing to not do, and just replace those tests with just random cat videos.

[1] https://github.com/ytdl-org/youtube-dl/commit/1fb034d029c8b7...
I find that lowes and home depot have very useful personalized ads. I bough some concrete repair spackle, they saw it in the cart and suggested all of the other tools I needed (degreasers, cleaning brooms, chisel, sandpaper) that I would need as well. Which is extremely nice because the rest of their site sucks. Amazon also seems to have a nice book recommendation system.

Just as a contrast to most of the targeted ads which are mostly a waste of time.
appending ?jpg to the url will sometimes get you the original jpeg file.

Failing this, browser extensions such as 'save image as you want' will do the trick.

https://chrome.google.com/webstore/detail/save-image-as-you-...
For all previous vaccines all side effects happened within two months. (with most of them in less than 15 minutes). We have no way of knowing when an unknown side effect might wait 10 years to show up, but there is every reason to think that won't happen.
The two groups would actually be the same. You can start with a number of people, randomly pick half of them to be given the vaccine, and the other half get the placebo. So there should be no difference, apart from getting the vaccine/placebo, between the two groups.
> It may not be a risk to the young people, but they need to understand that their actions have consequences for the people around them

"Okay, boomer."
Since someone just self-censored, I can only repeat that. As a young healthy individual, I'd much rather catch COVID then get vaccinated with a wide-spread mRNA experiment. In my childhood, I have been used by a doctor for an experiment without consent of my parents, and this cost me my remaining eye-sight.
You can bash, downvote, laugh at, deminish, and in general say whatever you want about sceptics, our reasons to not want to be vaccinated are as valid as your reasons to want it are.
Add the ability to turn countries please. Otherwise its brilliant.
This comment is the very definition of FUD and leans on to myths that have been debunked over and over again the last few weeks/months.
Normally this phase takes multiple years. You cannot shorten this. Long term effects, you guess it maybe, only show up in the long term.
You can have my dose, if you like. No problem for me. Please downvote me further.
Yep, this Web-app is cool! But, sadly, it overload CPU & RAM.

I'm preferring use offline tracker like Milky Tracker instead.[0,1]

[0] https://milkytracker.org/

[1] https://milkytracker.org/downloads/
Our solar system is just a few galaxy years old. Our circles (I hope they will be circles) around Big Attractor and Shapley Cluster are just started, so we are at year one.

If we scale up infinitely, then we will see that our Universe is "forever young", frozen in time.

If we scale down, we will see more and more exceptionally stable "dead" objects, completely missing short living ones, so our Universe will look "forever dead" for us again. Anything interesting will happen at our own scale only.
There is a line in Kingsley Amis's The Old Devils running something like "More and more, Alun's life was coming to consist of being told what he knew, at dictation speed." A book on maps that I got in elementary school laid this all out clearly. Every few years since about 1980, someone announces it as amazing news.
Yep, the proper syntax highlighting will follow when documented.

There was actually a massive internal discussion in 2015 re: With[x = 2, x + x]. And With[x = 2, x + x] actually did work for a time.

Unfortunately, several other ideas like With[x, x+x] and Module[x, x+x] (which was unintuitively NOT implemented as Module[{x}, x+x]) also got thrown into the conversation and things became confused, these uses were seen to be problematic, and soon the baby was thrown out with the bath water.

So technically yes, With[x = 2, x + x] could work, but it is unlikely that it will ever be implemented in product.
Nice...I bet the evil RIAA didn't think only about the two tests when they reported the project....
Great, now they can import the issues to a GitLab/Gitea instance hosted by the same Germans who refused to ever take down youtube-dl.org, and a few other places for redundancy, and not have to go through all this excess stress again.
It doesn't work like that since certain videos use obfuscation methods that random cat videos don't.
Well this was a wild ride from start to finish. Anyone got a count on how many times someone suggested distributing YouTube-dl via a blockchain in all these discussions?

Also, how come Google hasn’t asked for it to be taken down given that it has YouTube in the name?
Terahertz Networks Move Closer to Reality
MilkyTracker Domain Renewal
New Trend: The Future of Brands and White-Labeled Products
Ask HN: Price/performance benchmark for cloud VMs?
Recently read a price to performance comparison for GPU instances on AWS, Google Cloud, Azure and Linode (https://www.linode.com/content/gpu-price-performance-benchmarking/).

Have you seen anything similar for cloud VMs?

How would you set up such a benchmark?
Spain? Since when are they on our watch list? :)
HIV vaccines face tremendous challenges - almost 100% mortality rate if untreated, the fact that immune system activation helps the virus, very frequent mutations, lack of good targets for antibodies, etc. So don't hold your breath, mRNA is unlikely to help much in that case.
> which laptop brands today are most compatible with Linux

Why just not buy preinstalled Linux? https://puri.sm/products/
That would be rational, those with the least capacity to do the super refrigeration (developing countries also tend to be the hottest temperature-wise) get the one that need the least.

Not unless we fight for it I think.
The size of each library is not even comparable. Unless the AAA games that just came out is made by CDPR, you won't see it on GOG without waiting for many years.
That's true, but doesn't legitimate to do the same again of course.
Getting downvoted for giving Trump credit even where it’s due. Yikes.
I'm not sure about the details, but i imagine something like this;

If Apple breaks the rules by placing "cookies" without user consent/knowledge, they may need to be fined.

Whether they may or may not stop abusing the rules in the future, is a secondary issue.
Actually that's all they complained about.
Do‘s and Don‘ts When Creating a Pitch Deck
The old way of handing out corporate hardware doesn’t work anymore
There are features like IndexedDB that are disabled in private browsing but not in a clean install
What the Holocaust and Stoicism Can Teach Us About Living a Meaningful Life
Hi I like that there is a competitor to Kafka in this space and also the build in capability to do transformations. I got a few questions though which I could not find in your docs:

(1) Over at the Apache Arrow FAQ I read that the overhead of serialization in analytical frameworks can be around 80 to 90 % of total compute costs (r_1). While having no concrete numbers on this, from using Kafka together with Kafka Streams I can at least confirm that the overhead of serialization is (very) significant. My question therefore is: Does your WASM engine avoid (de-)serialization between your storage/stream layer and the engine and if not are there plans for this?

(2) Are supported WASM transformations stateless (i.e. single message) only or can they be stateful (i.e. window-ing and stream-stream/table join functionality)

(3) I could not find any reference to the WASM inline lambdas at all in the docs actually, am I missing something?

r_1: https://arrow.apache.org/faq/
I do believe execution is all the matters(from my experience) because ideas can always change.
Fantastic compromise.

Arguing that you have a right to break RIAA DRM is much harder that taking it out entirely.

I use this for downloading national archive videos off youtube, I'm very happy about this news
I get the distinct feeling that Ocaml’s leadership isn’t very interested in making a practical language, but rather playing with abstract type system ideas. Which is too bad because it clearly has a lot of potential. At this point, I think Rust will end up eating a lot of Ocaml’s potential market—Rust’s weakness is that memory management is harder than OCaml, but even that has become significantly easier between non-lexical lifetimes and rust-analyzer, and the pace of development of the Rust language is very fast while Ocaml moves like a glacier (still waiting on multicore!).
Another region offers remote workers-and a bike -to move
A Python App to Measure Your Coffee Grind Size Distribution
With COVID's 99% survival rate and the newness of this vaccine, I would treat this vaccine like LASIK - let the first adopters take it and wait 10 years for the effects.

https://www.medscape.com/viewarticle/926089
maybe not as the "warp speed" program is being prevented from interacting with the incoming administration who will be in charge of administering it, all for petty political reasons. this will likely cost tens of thousands more lives. pfizer did not participate in "warp speed" at all as they wisely determined that the federal government is completely corrupt for the time being.

https://www.cnbc.com/2020/11/15/dr-fauci-trump-should-work-w...
This is also a great example of how you can follow what sounds like logical principles to a completely bonkers end-state. Knowledge is protected but your bodily autonomy is not? Eesh.
Does everything really 'move' in time? I thought that time is like a film, where nothing moves except the observer. I'm not sure which way it is. If we travel back in time, the universe is still there, and not moved to the future.

Also, I never understood the grandfather paradox. If I travel in the past and change something, wouldn't the change propagate in time at the speed of light? And it would take a long time before it overwrites the original time.
Do you think the non-developed world only consists of dirt poor peasants? There are lots of people in these countries who this service would help. What you also seem to ignore is that many business in these countries would be helped by this.

Another thing you ignore is that if you combine Starlink with a mobile station you can potentially provide internet to a whole village.

Also, the prices will likely not be the same everywhere. SpaceX will want to get higher utility of the overall system and having unused sats fly over Africa is pointless. Lowering the price in some regions to get full utilization if an economic non-brainier if they would actually have issue selling the service.

In addition, the idea that this service wouldn't be worth it for rural people in the first world is very questionable. Don't rural people deserve good internet?
No, when a script tells a browsers to make a cross-origin request such as a GET or POST, the browser first makes a "pre-flight" request (without the payload) using the OPTIONS method to see what CORS-related response headers come back. If headers are returned that allow for it to proceed, the browser then makes whatever request the script asked for.

The network tab of developer tools should reveal all of this.
Yes, there should have been more pen testing and reviews before such an important service was released storing lot of personal information.

I'm happy I was able to find the vulnerability within 4 days of it's public release
Personally, I value functionality > performance > looking good. Also, I think MATE looks great. :)
I was under the impression that those obfuscation methods were exclusive to certain YouTube partners, including the RIAA members. If youtube-dl stopped supporting that method, it would still be a useful tool for the bulk of its use cases and the RIAA would no longer have any leg to stand on since it'd no longer be able to download their members' videos.
This is how you don't get to herd immunity and how you crash the economy for years.
I have trouble believing gitlab would just ignore a DMCA takedown request? This is what people believe? This is something gitlab has said?

Actually, I guess I'm not sure of the consequences to a company of ignoring DMCA takedown requests (whether or not they are US companies; but Gitlab is now btw), but I assume they are not good, or why do companies bother complying? Rather than assume, I should look into it.

But yes, redundancy for sure.
And not even purged from the repo, it's still in the history if needed. Seems like the copyright holders making a big fuss over nothing really.
That's true. And I don't think we can really eliminate the underlying behavioral pattern entirely. But we can limit its consequences and channel it in productive ways. Advertising was never properly constrained, and it's grown far beyond its usefulness for society; I think cutting it down to manageable size would already be a huge win - after all, we ultimately care about negative consequences of advertising, not about the concept existing in the abstract.
"Apple appliances are not allowed in this building. You can leave them in the bin next to the umbrellas. Thank you."
Was a counter-notice filed, or did github restore it without one, once the tests were removed?

Because my understanding was that certain decryption/anti-drm functions were also in the scope of the takedown request, not just the tests.
The protection rate oddly correlates with the hearsay that ~95% of people testing positive experience mild to moderate symptoms. I think I’m in the wrong business.
Synchronize the clocks how? Last I knew, this was still impossible, unless you employ hand-waving.

If I synchronize two clocks next to each other, and then move one away, they are no longer synchronized as one was moving. And we still don't have the speed of c one way, so you can't use that either.
This is the first time I've heard of lutris. Quick google search suggests that it is similar to proton.
When I worked for Canonical, one of my teammates had one - a 15" Retina MBP. He tried, for months, get Linux installed on it. In the end, he used a VM.
Cheating-Detection Software Provokes 'School-Surveillance Revolt'
How long before we start the discussion about exporting issues/comments and preparing for another event like this? :)
The thing is: I’m not even giving trump credit here. There are hundred or maybe even thousands of people working in the federal government on warp speed.
Anyone know something similar for Scrabble, with ranked online play?

It is good once in a while to get the feeling of getting better at a game by putting in some time and effort. Scrabble looks like just the thing for someone who finds chess too abstract and deterministic.
"Fauci also told CNN that Trump has not attended a meeting of the White House coronavirus taskforce in months. CNBC has reached out to the White House for comment."

get real.

https://www.cnbc.com/2020/11/15/dr-fauci-trump-should-work-w...
Who cares which is better.

If it works for you and your situation, great. Stop trying to make me change what works for me because you believe it would somehow be better.

Also can we just stop this endless bickering over irrelevant things like this.

I say this as a Linux user for a little over a decade, and someone who can not tolerate using Windows with its extreme need for bad system gui to be able to achieve anything, and lack of the software suites I have gotten used to.

You do you, and I will do me.

/edit: I am mostly talking to the comments here, not the document as I find it refreshingly non judgmental in its analysis of pros and cons.
I was simply asking a question because this sentence

>the third testing phase, which normally takes multiple years, hasn't started yet

is apparently not correct. Only trying to enhance my knowledge of vaccine testing phases, I don't want to fight you and I'm not downvoting you.
The amount of publicity this generated for youtube-dl is astounding... I would love for this to be a ”the plan to get rid of youtube-dl backfired badly for RIAA” ending. But I guess RIAA is reviled enough already so nothing they do really matters. So I suppose the hope is that some political will to change the laws around this arises from it.
That's true, but not a bad thing. We reward charitable donations for a good reason. Ideally, he'd have given away his fortune as he made it (and lived in a world where that wasn't risky), but we live in a world where it seems responsible to save millions or billions and grow them, then dedicate it something as you realize you can't take it with you.
Looking at that list it seems easy to get in one or two servings of fruit a day with that fructose requirement, so long as you don't get it elsewhere.

Thanks for sharing.
Yes, Linux and regressions, it is quite common and frequent annoyance. Many times I regret for not using some LTS distro, but stalled/outdated software stops me from making the switch.
It's an option now. Toggle the globe icon.
gitlab.com? No. https://youtube-dl.org/ ’s host? That’s almost exactly what they did. (Edit: here’s my comment on a story that details their response somewhat: https://news.ycombinator.com/item?id=24909982).
I'm now at July. Before this I was at early 2022. Every successful trial pushes my date back a bit. If the oxford and J&J both successfully finish trials by the end of this year I might push back to as early as march.

Of course roll out matters. Rochester MN (Home of the Mayo clinic) might open before the rest of the country just because the ratio of health care vs everyone else is enough that they may as well vaccinate the whole town and let it open up.
Robinson or Winkel tripel are probably the best here. Aitoff, Mollweide, Kavrayskiy, Wagner, etc. are all decent choices here as well.

One commonality all of these projections have is that they are pseudocylindrical instead of cylindrical: lines of longitude are not depicted as straight lines but as curved lines, with the curve being more pronounced the further from the central meridian you are.
Perhaps pfortuny is expecting the Spanish Inquisition?
Does this one also require transportation and storage at -70C?
hehe, have you heard of AVIF? :D
Git is simply too hard