skysight-inc/HackerNews huggingface dataset:
This just goes to show how difficult a problem cancer is. These companies were working on therapies for cancer, switched direction and in 11 months developed and successfully tested a vaccine against a newish virus. What's the progress in cancer treatment in those 11 months with vastly larger resources? Is there even a 1% improvement in survival across all cancer types compared to last year?
History of replacing JPEG with something better

- PNG Mostly to replace CompueServeGIF (Not to be mistaken for Yiff files). Neat but no real gain over JPEG in quality on photos so nonone really used it for anythign but animations, but everyone were already used to GIF in their workflow so.. meh...

- JPEG2000 1997-2000 embroiled in patent nonsense so noone really uses it in the wild.

- WebP: used by google to look cool but since most people used a webbrowser that does not support it at launch servers were forced to have JPEG's as fallback. Great savings much wow.

- HEIF: Absolute cluster fudge of variations then Apple did a big Dick move and said "Orchard says HEIC, or Bust!" without actually telling anyone and broke several people's workflows that depended on JPEGS form iPhones, especially since FCPX did not support HEIC on launch and it took another 6 months for that update to come. Yay.

- WebP2; Google want to swing big dick dev powers to gain a marginal possible performance savings on their servers and say's "WebP? That is sooo 2015! you gotta be on WebP2 to hang with us"

Is it really that surprising that most people who depend on workflows to actually work to make their money are still using JPEG, GIF and TIFF files?
By that definition how is anything ever unnatural? Everything comes from the Big Bang so everything is natural?
The Surest Path to Freedom Is Removing Your Software
Interesting. The next paragraph explains more what they mean by that:

"Jeffrey Almond, a visiting professor of microbiology at William Dunn School of Pathology, University of Oxford, told Sky News: 'All the current vaccines we have: diptheria, whooping cough, polio, measles, papillomavirus, you name it; all of them are very different. You don't have a generic process to make them. You have a dedicated factory, a dedicated process, very different technologies.

"'What RNA and DNA offer is an escape from that. We can make the RNA by a single process in a single factory. All we have to do is change the sequence of the RNA or DNA.'"

Very cool, but not necessarily "universal" in the sense you'd need to target all the different rapidly-mutating cold viruses.
I’ve written about it here: https://twitter.com/amadlonkay/status/1260924102161821698?s=...
Without social media and news organizations forced to whore themselves for clickbait money it would have been just written off as "damn those two pneumonia seasons were really shitty" .
Didn’t see if this was mentioned in the article, but it was interesting to find out somewhere that for a photon time doesn’t pass even as it travels across the universe. Basically the time component is 0 so the space speed is 100%.

That’s why I find it easier to stop thinking of the speed of light, and thinking of it as percentage of speed of information transfer in the space-time medium. Light (or rather electromagnetic waves) travels at 100% the speed of space, but it has no special treatment in the medium, and does so by travelling at 0% the speed of time.
Agreed. I worded that poorly. That is why I am saying the intelligence agencies won't have it. They would use policy to get the data, which ultimately translates into a court order. Failure to comply with the order would alert investigators to a bigger problem.
From the wiki...
"Notice that neither observer can actually "see" what is happening in Andromeda, because light from Andromeda (and the hypothetical alien fleet) will take 2.5 million years to reach Earth. The argument is not about what can be "seen"; it is purely about what events different observers consider to occur in the present moment."
Nvidia A100 GPUs get double the memory with 80GB HBM2e
Several other apps I use simply display a warning when used on a rooted device. Ultimately, the problem here is one of recommendation vs enforcement.

Would you tolerate a bank that insisted on coming in to your house and forcing you to install Norton Antivirus on your computer before they allowed you to log on to your online banking via their website?

Banking security should be implemented on the server side. I shouldn't have to choose between running my own code as root on my device and being able to bank.
My suggestion from personal experience: less red meat, seafood, beer, wine alcohol. Drink a lot of water everyday.
what does WASM mean in this context?
This vaccine is incredible because of mechanism of action! If it continues to prove to be safe, we can treat all sorts of rare diseases easily and cheaply.
Not all of us mate, I don't actually recall any ads because I block them extensively .. through software online, through habits of avoiding tv etc, changing channels or muting radio ads, and then mentally tuning out anything that gets past that .. I love the peace of mind.

I'm an avid consumer but I believe my interests are best served by a pull model where I research the things I want to get best in class. Then anything that spends an excessive amount of effort on advertising is wasting their budget which could go toward a better product and lower prices! So that helps me avoid advertising driven products, as well as advertising. #winning :D
Hold on a second. The Russian vaccine has 92%? And is available for months already. WTF is happening actually? Did the governments around the world smeared Russian one on previous months mocking it and ridicule it in order to allow a Western company to achieve the same protection for the love of money? If that's the case I hope people with deaths in their families will sue their governments/health organizations to hell and back. This screams of greed for money not on back of ordinary citizen, but literally on their life.
Competition is always good!
> Github API has CORS setup

I know perfectly fine what you mean here, but in the name of security, it's important to be precise.

All websites and browsers have CORS, one way or another, as CORS is the general concept. By default, only "same-origin" requests are allowed and "cross-origin" requests are disabled. But CORS is still there none the less.

What GitHub has done in this case, is add support for "cross-origin" requests.

Nitpicky maybe, but thought it'd be useful to add to avoid any confusion.
Hazel 5 Released
What puzzles me is those serology studies in Spain and Italy that show that people who were locked down were infected at the same rate than essential workers who were not locked down (except, understandably, for healthcare workers). It seems to be a major data point on whether a lockdown actually has any impact and it seems to have been completely ignored.
Why does it matter if a camera supports WebP or not?
The problem is that the main business of SpaceX and Arianespace was GEO sats. Those have been in a slump and fewer launches existed. Maybe that will pick back up, but the largest part of that were for Internet and after that TV, both don't seem like huge growth markets.

Small sats have become so powerful, that on a SpaceX Rideshare you can deploy basically a whole constellation in one shot potentially. Most sats today are no longer that large and heavy that you have dedicated launches.

Many of their launches are government, both domestic and foreign.

SpaceX has not reduced the price 'that much' in the last couple of years. They were already the cheapest on the market and opted for more profit, so they could have better cashflow when going into Starship and Starlink.

What also has to be considered is that even that 12 is a pretty large number. Large rockets usually didn't fly that at the rate SpaceX flies them.

The sat market is slow the respond, 4 years are very little in it. Hopefully people will come up with more great ideas how to use the capability SpaceX offers.
Did you read the article? Your TLDR is misleading.
There is (for now) an approximately zero percent chance that Biontech can be bought by either a US or Chinese company.
I'm still confused, because you are not giving any example or explanation for "one of those things".

As soon as you tell somebody how to make their money, outside of government regulations, you are in fact an employer.

Which is different from a contractual work where you can define requirements. In the case of Uber/Lyft (and other Gig economy for that matter) you do not sign a contract with each transaction you do with them.

Therefore, your contract with them, it's to pick up and drive users of the platform under terms set by the platform. This is obviously an employer - employee relationship.
Safari reader view helped me.
I have hope that the mRNA based vaccines will enable economies of scale and provide insights into delivery mechanism and safety which will then in turn speed up the development of cancer treatments.
May I bro-science it for a second?

I shy away from blaming high-fructose corn syrup as some sort of subtle poison. A gram of HFCS is anywhere from 42–55% fructose, which is the same as what you’d get from an apple.

But I think there may be something to the dose of HFCS.

Fructose has to be metabolized in the liver, and there’s an upper bound of how much it can break down at once. (I believe 50 grams.) Which, if you’re eating fruit, is fine; the fiber slows down digestion, and also you’re probably not eating like 6 apples at once.

But oh man, look at an energy drink, or a sugary coffee drink. I am from Midwestern white trash stock, and during my obese younger years, I would frequently drink a 44oz Big Gulp of Mountain Dew. That’s a shotgun blast of fructose, and my gut instinct (hah) says that there’s a dose-response curve going on here.
I did a similar thing. I bought a Gameboy and modded it for music production, but by far the most time I spend with it was playing Tetris DX where I started from failing really early up to the highest levels (that give you the rocket launch ending). It is a terrific device to play Tetris. No colour, no distraction, 30h of pure Tetris with one set of batteries.

I am however missing that you can't start from higher levels than 9 (thus forcing you to replay boring bits) and it is missing the modern Tetris features like holding and hard-drops. Somewhat surprising nobody implemented modern Tetris for the classic GB yet.
WebP was introduced in September 2010, Mozilla started supporting it in Firefox in 2019, and Apple is just adding it to Safari now. You think they should have waited longer than 10 years?

(Disclosure: I work for Google, speaking only for myself)
How does that affect the discussion about jitter and other aspects of link quality?

With only a tiny bit of the relevant subjects under my belt, I would expect the metrics to be significantly worse using a much smaller dish. But it seems like you're suggesting Starlink could achieve similar metrics on a smaller dish? I'm curious how that works. Apologies if I'm misunderstanding.
The sentiment here and in the article isn’t what caused Apple to enact the change, it was the negative publicity timed to coincide with the launch of a new release of their flagship operating system. The incessant drone of “Apple owns its users and they’re basically slaves to their own devices” is what annoys people so much.

There is no such thing as a perfect computer. Every purchase involves tradeoffs, including Linux. I, personally, started out on Macs in late 1995 and then switched to Windows in 2002. A few years later I switched to Linux and then ran Arch until summer 2017. I switched back to Macs with a MacBook in fall 2017, just as I began university.

Why did I switch back to Mac after all those years learning Linux? Because I was tired of my computer breaking all the time. I wanted something that would just keep working and not randomly boot to the system console, unable to start the graphical shell, after an update. This tradeoff in stability came at the price of customization, something I was glad to give up anyway since I knew I’d have a ton of actual work to worry about in school.
Funny that you bring up Feynman, he stated he only had an IQ of 125. High, but probably lower than Kasparov.
Why would you be opposed to that?
I had a similar progression also in two years, from only knowing the rules to 1658 last week (my peak rating so far).

But this is rapid rating, not Blitz or bullet, and I only play 45 minutes matches with 45 seconds increment on chess.com (which I think is not actually classical and not rapid, but marked as rapid on chess.com).

I don't do puzzles, study cards or anything, I simply took a couple of opening video courses from Simon Williams on both white and black, and played those exclusively.

Initially I played 15 minutes/10 seconds increment games, several a day, until I felt that I was losing a lot of winning positions only due to time.

Then I increased to 30 minutes, and now 45/45 which is almost a classical format.

I don't think playing short time formats is ideal for learning, I like playing longer ones and really think the games through.

Then analyze each game thoroughly with chess.com post-game analysis.

I only play one game a day, almost every day. Most games end in well less than an hour, but some take close to almost two hours (due to the increment and long end games).

I think like in any game, if you continuously play with opponents of just about your skill level, and you analyze your games to make sure that you are not making the same mistakes again and again, you will improve over time just like with anything.

To minimize rating fluctuations and tilting, playing only one long and well thought out game a day works great and keeps it fun.

I think to keep it fun, it's important not to forget that rating fluctuations are normal and don't mean much. As long as you keep playing and analysing each game, improvement is possible.
But this coronavirus is not capable of exponential growth. It does spread quickly, but not that quickly. The most well known exponential growth model of SARS-CoV2 infections is the Imperial College model which has proven to be at least one order of magnitude off in its predictions. The most accurate model of SARS-CoV2 spread currently available is that published by Michael Levitt which predicts SARS-CoV2 comes well short of exponential spread even in worst case scenarios. The only reason we thought there was exponential growth is because the beginning of the epidemic was so poorly understood.
Why does everyone want to appear normal? Who cares.
Exactly, early on we weren't sure what the risk of covid was to the average person. It feels like now their is enough data on cases, broken down by age, where you can assess your own risk.

If you are under 25, the risk to you from Covid is basically tiny. I can understand young people not accepting having their life destroyed from living under a lockdown over a virus that is unlikely to do them harm.

In Scotland

Infections Hospitalization Deaths
0-4 1,137 62 0
5-14 2,973 30 0
15-19 6,771 41 0
20-24 7,896 65 1

I think we need something smarter than a blanket lockdown that affects everyone the same regardless of age. How we are 9 months into this and still haven't figured out anything better is really disappointing. We are destroying peoples lives, income and mental health when for the majority of them there is no risk.
You may be right about funding, but it can also be attributed to incentives: has our desire to eradicate a disease ever been expressed in such an intense way, with the benefits being so enormous?
Yes but Apple keeps track of the application you open and sends that data through 3rd parties unencrypted.

Imagine you open Tor in your mac, Apple will send a request with Date, Time, Computer, ISP, City, State and Application Hash through the open internet for everyone that listens.

That by itself is not very interesting but if you combine that with all the other data hoarding that happens it can trace back to you.
No you misread my comment. I never said fructose is indistinguishable from glucose. I said sucrose is almost indistinguishable from high fructose corn syrup.

Sucrose is 50% fructose 50% glucose and most high fructose corn syrup is 55% fructose 45% glucose. They are almost identical.
They are planning to do just that in the UK https://www.nature.com/articles/d41586-020-02821-4
Thanks for this! Never thought about it this way, but it's a terrific perspective / way to frame and explain probabilistic measurements in an intuitive way.
This "study" is useless, to put it bluntly. The "full report" from RSA is available here: https://www.rsa.com/content/dam/en/misc/rsa-data-privacy-and....

The majority of the 16 pages are just business "takeaways" and "insights" based on the headline results. The only information about statistical methodology I can see is that roughly 6,000 adults were surveyed in America and Europe by YouGov for 9 days in December 2018. There is no breakdown of raw response data by age, country, region, income, education or other demographics. Moreover, there is no discussion of techniques used to reduce sampling bias (for example, by broadening the survey time over a longer period and by specifically targeting more demographics).

Don't draw any conclusions based on this report. This is content marketing for RSA services with a thin veneer of academic polish.
YouTube-dl's repository has been restored
This is so brave. A modern version of a hero. I look into the future and see that these people will be considered trailblazers of their time. It's a life and death situation changing OSs, we should idolize them.
Of course, the perceived risk is quite different from the statistical risk.

Currently, about one in 4000 Scots is hospitalized, which says that approximately only one in 40 Scots directly knows someone hospitalized with COVID, assuming they know 100 people each.

However, the chance of directly knowing someone that had a positive COVID test is 1 in 40, which says most Scots will know someone who had a mild case of COVID.
Fun, or not-so-fun, fact: Dalmations are severely genetically disposed to gout.

https://en.wikipedia.org/wiki/Dalmatian_(dog)#Hyperuricemia
PyDev of the Week: Max Humber
I was wondering this too. I guess the trick would be how would you (the attacker) know which filters are being used / which are expensive?

If they're only using the Snort standard filters, that would be one thing, but Cloudflare or similar services which might actually use this hardware would probably also have a completely custom rule set. So could you somehow detect experimentally what packets trigger the expensive rules? Perhaps some kind of fuzzing attack could do that.
I found it an enjoyable reading - I agree it is not very helpful for the patient.
Take a look here, you can see what works or not according to users: https://wiki.archlinux.org/index.php/Laptop/HP . This URL is for HP, but there are pages for other brands as well.
Stephen Wolfram on Computer Language Design, SMP, and Wolfram Language
what was true?
So may every day of rushing. These testing/approval protocols aren't designed simply to provide job security. They were much cheaper and quicker before events like this one: https://en.wikipedia.org/wiki/Thalidomide_scandal
Pandas Tricks That’ll Make Your Life Easier
It would help if there was something to show the scale of the slide rule in the pictures.
That is still considered a landslide in the world of politics. Despite the attempts by conservatives to see some light at the tunnel, the conservative ideology will always be a rump party in communities of color.
Ornatos Violeta = instant upvote.

Here's a perfect live of another one of their songs: https://www.youtube.com/watch?v=eBN-ruyacSs
That sounds interesting, could go more into how and why?
https://webassembly.org/
Oops yes, my mistake. Thanks for the correction.
Not at all likely
reviewing profiles one a time allowed them to jam more ads down your throat. it ruined the experience and made it way more time consuming to use their app
You can't really take your personal antenna in a train. The train provider would have to do this for now.

On a personal boat this is less of an issue, but for most large boats the operate would install it and then offer local WLAN I would expect.
But the entire point of relativity is that there’s no such thing as a joint “present moment” between more than observer. The only meaningful construct is your own present moment, about which information radiates outward at the maximum speed of information transfer in space-time (speed of light/gravity). Information reaches other observers based on their trajectory and position in space time. No such thing as the universal now.
> How long does the immunity last?

If we consider that recovered patients are immune between 6 and 8 months at least, that timeframe seems likely.

> What are the long term side effects?

I keep on asking myself. What vaccines do truly exhibit long term side effects? Narcolepsy with the 2009 swine flu vaccine or the Guillain-Barré syndrome for the 1976 flu vaccine do not fit the bill, because they actually showed up in the early months after administration (although some were found out later).
What migration? Most of the code I have run in the cloud in the past 5 years has been in the form of managed services. I don't really know or care if AWS is running my code on ARM or x86.
They each have their own. So 2 billion doses.

I believe that if Moderna found their vaccine didn't work they would license the Pfizer one as I assume their factories can be converted in a few months. Note that these are mRNA factories - I wouldn't expect a someone working on a different type of vaccine to be able to convert their factory. I would also expect that the process of conversion to produce a different vaccine will takes some months and cost us half a billion doses next year. This is just speculation though, there is no reason to make a license deal so we won't find out.

You can assume all manufacturers are watching each other. Some of the "getting ready to enter phase one trials" vaccines will probably be canceled as there is no point. If one of the promising candidates in trials fails Pfizer and Moderna will build (or license) more factory space because there is less competition for the demand.
This isn't about funding... this is about taking a giant leap into mRNA vaccines, that until now have not been approved for human use. We aren't injecting processed proteins into our bloodstream to trigger and train our immune systems... We are reprogramming our bodies into vaccine factories.
The Russian vaccine (Sputnik V) was not available and as far as I can tell still isn't. The Russian government rubber stamped it before it had gone through proper trials.

See: https://www.cnn.com/2020/10/27/health/russia-coronavirus-vac...

(If you dislike CNN feel free to Google "Sputnik V" for plenty of other sources on why this vaccine seems very sketchy).
It can cause problems after months or years. It's just question of risk management.

>Where did you get these timeframes?

From government regulators in different countries. There are accelerated approval and fast track processes.
It's being mocked for being insufficiently well tested.

https://www.sciencemag.org/news/2020/11/russia-s-claim-succe...
Intel can distribute its overhead costs over a lot more CPUs than Apple, and Apple pays TSMC for making the chips, so, presumably, a large fraction of the marginal profits go to TSMC (probably not all of it, as I think Apple paid for building production capacity up front)
President Trump Declares Election Victory
No, it meant that just because I will never buy Windows does not mean I will go around bashing it. That’s why the next sentence said “I don't go around shouting my reasons why I won't”.
It's not underfunding of drug research and development. It's the FDA restrictions, which have been relaxed for this drug, and they've been expedited through the approval process.

So maybe more funding for FDA, contingent upon them speeding up the process.