skysight-inc/HackerNews huggingface dataset:
Started having severe gout attacks in 2004. Doctors are particularly unaware about gout. Despite having extremely painful and long attacks (during one attack, spent more than a month in bed unable to walk), all the doctors I saw had no idea despite endless tests. Finally based on my own research I suggested gout and they were like "oh yes, I suppose it could be that".

Once diagnosed, doctors are quick to get you on daily drugs for the rest of your life. While these help, there's a price to be paid in liver damage from chronic medication.

I spent the next ~8 years bouncing from attack to attack despite the drugs, sometimes every few weeks, sometimes months would go by. Finally around 2012 I stumbled on the work of Robert Lustig (UCSF medicine professor) and particularly this talk (not about gout, but touches on it):

https://www.youtube.com/watch?v=dBnniua6-oM

Fructose is processed by the body into: uric acid. Finally light bulb moment! I hardly ate any of the things traditionally associated with gout (red meat, shellfish) so couldn't modify my diet based on those. But fructose? Yes, turns out I was consuming way too much.

I drastically cut back on fructose, limiting myself to no more than 10g/day. I have been gout-free now for 7 years. I don't take any gout drugs anymore. Just avoid fructose at all cost.
For some user categories, Linux is simply not a choice, whether you like it or not.

E.g., for musicians. There's Reaper/Bitwig, but you no longer have Live/Cubase/Logic/etc. Your multi-$k audio interface no longer works because its proprietary drivers only work on macos/win too. None of the hundreds of plugins you have work on Linux either. So it's between win/macos most of the time and the choice there is obvious.
yeah transmeta c1 had the same claim. turns out there's a lot more to cpu speed than executing math operations in a straight line.
Do you have a real world example? For example, what are you spending on a single app server? And how many RPS should it handle?
Ask HN: Do you have any idea how can I get lead for DevOps service providing?
Mobiloitte is bringing together people, processes, and technology, automating software delivery to provide continuous value to your users. Do u have any project or query ?
> most diuretics

Does that include caffeine and phenylalanine?
Matt Parker from Standup Maths made a great video on exactly this subject a few weeks ago.

"Does land area assume a country is perfectly flat?"

https://www.youtube.com/watch?v=PtKhbbcc1Rc
Zoom has nothing to do with electron
Bill Gates and Rashida Jones Ask Big Questions New Podcast Series
The OS is already endorsed: https://www.gnu.org/distros/free-distros.html.

The device itself has a preliminary endorsement: https://www.fsf.org/blogs/community/ethical-tech-giving-guid....
Convert Image to Jef File
For complete cheers beginners who want to learn and understand the ideas of the game, I highly recommend buying an oldish engine, Chessmaster XI: Grandmaster Edition, as it contains a set of amazing, approachable tutorials by an IM Joshua Waitzkin. You might know him at the author of the Art of Learning book.
Some will say that the program is old. It is. Who cares, the engine is strong enough for you, of that I'm sure, and there isn't much else you'd want as a complete beginner.
In Germany, if you have a heat pump you can get special discounted rates if you let the utilities company switch off the pump for some time during peak demand. The same scheme could immediately be used for electric car charging. Actually I expect the utilities to be a big pusher for charging infrastructure, which is then controlled to even stabilize the grid.
I am working on supporting pg's website as part of rss-proxy [0], unfortunately its quite an odd markup.

[0] https://github.com/damoeb/rss-proxy
Great excuse. If your research is so important, maybe let blind people read it?
> My doctors insist that I cut down my drinking (I don't drink), my consumption of red meat (some, but not much) and a variety of other things which mostly don't apply to me.

See my other post in this topic. Try cutting way down on fructose.
You have a government which seems to try to out-Trump Trump on China, not recognising that the US-China policies are about to do a 180 and you guys will be left holding the bag - the bag of having pissed off your biggest export market.
Heat is killing more people than ever
Same here. I'm 41 and had to stop playing Hollow Knight because I can't progress anymore. Sad, because I really liked the game.
You are right. I find it helpful to look at risk. Broadly speaking there are two types of risks when starting a startup:

1. Customer/market risk

2. Invention risk

When invention risk >> customer risk (you can be certain there are customers, they have a need, you can satisfy the need), then a good idea will play a bigger role relative to execution (which still remains crucial).

However, we tend to grossly under-estimate customer risk, hence the "ideas are cheap" warning.
I think it comes down to what interests you. Nuggets like how different map projections impact size and shape of the earth is the kind of thing I would never forget.

Other kids could discuss specific goals, matches, titles and football players; sometimes from foreign leagues. Even though I vaguely enjoy watching the odd match, the details would instantly be lost to the ether.
But without the label that said "Vietnamese food" did you know "Coffee and Bánh Mi" was "Vietnamese food"? /s
I have social anxiety and started a company. Social anxiety is not the root cause. Sales and marketing (entrepreneurship) is indeed at the hearth of a startup, but the difference is I find these activities fun and rewarding, and a huge opportunity to learn and grow as a person.

So much to learn like writing, doing presentations and conducting a sale (B2B), public speaking, crafting a brand, hiring, designing processes, organizing and managing teams, company structure and culture...

I love to code, but it’s a small part. The larger “real life build your company strategy game” is more interesting for me.
It precisely describes targeted ads, using user data that's been generated by monitoring their activity to sell something you want to sell them.

Advertising is all, pretty much by definition, entirely unlike a friendly recommendation. It has a profit motive.
Maybe it’s because Apple/ARM can ditch all legacy x86 stuff so the chips only contain instructions relevant for today, saving space for more transistors to do these relevant instructions or just to keep the chip smaller and more efficient
This is what Bloom filters would solve. I believe another poster said that Firefox uses them to quickly check valid certs.
> I do not want to squash your hopes but with dietary changes alone it is not possible to stop progression of gout.

We all might get gout for different reasons but the generalization of "with dietary changes alone it is not possible to stop progression of gout" is not true. I have completely stopped my gout attacks by cutting way back on fructose.
Danish military intelligence helped the NSA spy on Danish government
Seconding this! Lichess is also free/libre and open-source[0], and has a really nice API[1] allowing you to do pretty much anything you could think of wanting to do when it comes to online chess.

[0]: https://github.com/ornicar/lila/

[1]: https://lichess.org/api
This is helpful. I was a pretty rabid atheist in my 20s(not proud) and over the years, I have constantly recalibrated my atheism and have swung between ignosticism and agnosticism to exploring faith.

there was no rational basis for atheism either. agnosticism seemed to be a comfortable nook to hide under but as one gets older, one starts questioning that too.

i have considered cults. holding a human guru to a higher esteem seemed an easier pill to swallow than an invisible omniscient/omnipotent being. but that duck didnt even waddle, never mind fly.

i went back to my own faith of origin which was easier to navigate. perhaps it was easier for me as it wasnt an monotheistic faith, but it still required 'faith'. i have since started studying astrology because it had a deistic component alongside solid mathematics/astronomy concepts. it's still muddled, but it a 'language' i can understand without too much baggage.

i do want to 'believe' in something ultimately. i feel lucky enough to be in a place/time where i can define it on my terms. the question tho' is:

1. why does the populace have Faith?
2, what are it's benefits? vs downsides?
3. why did it evolve and thrive? religion and the notion of a God has staying power. this shouldnt be dismissed.
4.i am not dismissive of Faith as I was when I was younger.(how we change!!) clearly it has its upside. or it wouldnt have survived over the centuries.
5. what is that comfortable 'sweet spot' where i can have a intersection of the benefits of Faith and Rationalism? I do feel like I want to subscribe to a "supernatural" Faith rather than A God.
6. My escape is Sci-Fi. Will AI play a role in shaping future Faith?

I envy those who have Faith. I really do. A decade ago, I might have been facetious, but no longer. I am weathered and mellow. I dont want to fight anymore. I want to understand but also want the freedom to observe it as an outsider to most organised religion.
I think the parent comment does mean underestimating the _range_, but overestimating the IQ, as you point out.
Highly recommend lichess.org too. Completely free, open source, runs on donations, no ads or constant nagging to try premium.
Implementation wise, there are probablilistic DSs like bloom filters which solve this very easily with further checks necesssary for false positives.
By what scheme would an irreplaceable object become priceless? In all pricing schemes I can think of, it's value either doesn't depend on or goes up with its uniqueness.
By cutting out “fructose” surely you don’t mean cutting out fruit? Do mean derivatives like fructose syrup and stuff?
Yes ...

But these are the easy edge cases. It should be trivial (it was trivial) to rebut.

The problem is not that there was no evidence Obama was Kenyan, it's that there were plenty of people who wanted to believe it. Because they did not want a Black president, or because their mental model is so far away from reality that they think it's possible for someone to cheat that huge.

Then the issue is not everyone having same facts in front of them - it's everyone being willing to accept facts, and so change their own mental models. And then we are back to politics.

Look, I fully support some system of global rebuttal. It will mean no politician can open their mouths without opposition rebuttal - but that's pretty much where we are now in mainstream media. (it's an argument that this is an attraction of online social media - there was no rebuttal (at least no rebuttal that appeared in the same timeline)

I am less happy about the idea of FAANG deleting posts - deleting criminal posts is a tough call (which crinalmlaw to use etc), deleting minsinformation - that's a huge open wound

But the issue is not misinformation - the issue is fertile ground these posts find. And that is about mental models and that is about changing peoples internal mental models of the world - that is getting others to agree with you and that is human politics - and there is no tech fix for that. That is schools and education and society and diversity and a feeling of belonging and investment in society and shared protection.

Surprised the countries with the poor welfare systems have this problem worst? Don't be.

Worried about politicians who are always facing rebuttal - just imagine a world where politicians have to treat their statements like scientific publications - we might start getting somewhere !
Comodo open-sources its EDR solution
I'm Basque, I'm a very long time HN regular, and I love linguistics related topics. So I'm keen to see this, but I still don't fully understand how this makes it to the front page :)
Do give KDE a try. I recently helped a friend migrate from Windows 10 to KDE. I have personally been using i3, XFCE and GNOME back and forth during the last decade, and the one time I tried KDE a few years back, it did not boot to desktop so I just switched back to GNOME.

After helping my friend setting up KDE I discovered the level of polish and customizability that KDE now offers. That same day I installed KDE on my own machine and soon after removed every GNOME component from my system. I have been using it the last few weeks and really feel at home!
> Never tried it with an AMD APU, but I would hope it would be the same with the open source amdgpu driver.

It is a big regression that won't ever be fixed, OpenGL 3.3 instead of OpenGL 4.1 and barely working hardware video decoding.

Yep, it is a 10 years old hardware, yet Windows 10 drivers are perfectly capable of handling it properly.
Because drugs that only help a handful of people are excellent bargaining chips for pharmaceutical companies when dealing with national governments for coverage of drugs in national healthcare insurance plans.

It's the basic economic law of supply and demand applied to human lives.

The same happens (or happened) with the drug that treats Pompe disease, which is currently priced at a sweet spot high enough that enough insurers can cover it to make massive profits (but some refuse to, because the amount of money spent on it can be used to save more lives when invested in other areas).
> Advertizing works

In a brute force sense yes. Word of mouth works far more efficiently.

Let's face it you can pay enough money to make nearly everyone on the planet think that grey is the best colour, but was it worth it in the end?

Millions of negative return marketing cases exist from this year alone. Marketing obviously doesn't work that well otherwise they'd all be the richest people on the planet and still yet convincing people to pay them even more.

Reminds me of the "With $1000 I can earn you 200% annual returns" If you really could do that why not use your own money?

People will get smarter, advertisers seem to ignore this.
That is not true. Natural sugar (e.g. sugar cane) is 50% fructose. HFCS is by definition a compound sugar with more than 50% of fructose. How much higher, depends on the manufacturer.
In Europe everyone has a word atlas for geography class, and the various projections are explained literally on the first page.
I guess since I use addblock I already am ignorant.

Feels a lot better then seeing every website plastered with foot fungus cures and stuff I just bought the other day.
Time alone is not enough to reach the top 5% or better in a game. You need to be focused and put a lot of effort into improving.

It's quite draining, and nothing like watching TV.
Open source as well: https://github.com/ornicar/lila
> There is a minus sign and the speed of light in front of time in the space-time metric.

Yes, that's called the Minkowski metric, and it's absolutely nothing new.

You can do the exact same physics with the opposite sign convention (called the signature of the metric), where time has a positive sign and all three spatial dimensions have negative signs; the only rule is that time has to be the odd one out, so rotations in a space-time plane obey hyperbolic geometry as opposed to Euclidean. You can get rid of the factor of c by moving to a different system of units, commonly called the natural units, where the speed of light is 1.

All of this is covered in any real introduction to Special Relativity, which, in turn, is at the beginning of any course on Modern Physics, as opposed to the Newtonian Physics.

Welcome to Spacetime:

https://www.av8n.com/physics/spacetime-welcome.htm

THE GEOMETRY OF SPECIAL RELATIVITY with the quote:

Lorentz transformations are just hyperbolic rotations.

http://sites.science.oregonstate.edu/~tevian/physics/paradig...
Gout at 24? Congrats on the new record!

But seriously, the US as a society needs to get a handle on our level of decadence before things truly spiral out of control.

The destruction of the nuclear family and metabolic illnesses are epidemics more serious than corona.

Just look at any youth group photo from the 1960s - nobody is fat.

Here's a thought experiment. Imagine a normal-weighted young man who walks into a military recruiting center today. He would be like chum for Jaws.

https://www.healio.com/news/rheumatology/20180808/patients-w...
There is a solid argument to be made that the minuscule effort we put into life extension research has moral weight that will haunt our descendants.
I'm very direct sometimes.

Like it could be that my wife wants to be nice to me and buys something specific and i just say 'ah you shouldn't buy that, it produces so much garbage (lots of wrapping)' and she answers 'yeah i know but i thought you like it so i bought it for you'.

Might not be the perfect example but whenever something similar happens, it feels to me that i took a little bit of 'fun' and 'nice gesture' out of our relationship by saying this kind of things.

On the other hand, if i would never say something (and of course vice versa) we would be stuck but we would not have those small disappointments in our relationship.

But i regret those things because it is much nicer to see your significant other being happy about making you happy.

It is so much easier not to offend someone when you just follow your own set of rules for yourself. Like not telling someone, who just 'drooped' garbage that they just 'drooped' garbage. It is 100 times harder when it is your partner.

Now we don't have any secrets between each other anymore. But that was a long long way and not easy.

Now imagine a Relationship which wouldn't do that. You can easily start living next to each other over a longer period of time and then suddenly you realize that you crossed that border.
And indeed, why not at the city level too :)

I cannot figure out why global taxation and the ensuing coercion (IRS,FBAR,FATCA,citizenship exit penalties) doesn't fall foul of some part of the US constitution, such as cruel and unusual punishment for not committing any crime other than earning some money some place else. FATCA also demands extra-territorial jurisdiction over foreign banks, which is outrageous.

I am sure when the time comes, the IRS will try to enforce pan-galactic taxation...

Elon will have to renounce before blast off to Mars.
> 3D-printed?

With typical consumer-grade machines that produce garbage bathtub-toys, no.

But there's high-end commercial machines that are more capable.
Australia bourse suffers full-day shutdown after software glitch
Warning: this is a survey on what people THINK makes great engineers.
Extremely small - probably in the megabytes range I would guess.

Think about antivirus definitions - those are many, many times larger, and still they have been kept up to date over the internet for decades.
GPT3 has some impressive results with generated code [1]. I don't think it's production ready but it seems to have potential to one day replace a room of frontend devs with just 1 dev to clean up the code.

[1] https://twitter.com/sharifshameem/status/1282676454690451457...
So why do you think there is huge performance boost when plugins are sandboxed and running in their own processes?
The point is the gpp

> Mac OS is not Windows, it doesn’t install automatically and the prompts are much more reasonable.

It does by default.
I noticed same thing some years back. Don't let the social medias work ON you, push trends on you. Ignore all suggestions. Keep it minimal and use only for your personal goals. Importantly stop notifications on cell phone.

Facebook I stopped using a while back. It gives me the feeling of universal garbage bag where everyone in a race to impress others. On twitter I follow top people from my domain and ignore everything. No political BS. In LinkedIn, I literally removed all HR connections and started to follow people whom I really adore and take direction from their career path.
> And it ended up costing $33 / month just to have a NAT set up to route all of the internet traffic between these services.

Yep, this matches my experiences with AWS too.

The stuff that you THINK might cost an arm and a leg, are actually really cheap. Billions of lambda calls with thousands running concurrently? meh. Huge SNS/SQS-queues? Meh. Terabytes of data stored in S3? A drop in the bucket.

BUT.

Too many PUT-operations on S3? $$$$$expensive$$$$$ Too much IO on an Aurora instance? Pucker up! Need some sane network configuration? Prepare to pay up the wazoo for gateways.

Yes, all that can be worked around, but it's really non-intuitive to actually see where the pain points in a project will eventually be.
Nobody else considered these two sentences, pretty much one right after the other, quite at odd with each other?

> These books are extremely valuable, but more importantly they are irreplaceable and are of great importance to international cultural heritage

> The works were being stored in a warehouse ahead of being transported to a specialist book auction in Las Vegas, in the US

So, they were of great cultural/historical importance, yet they were about to get shipped of to the USA to be auctioned. In Las Vegas, of all places.

If that was to be an open auction, where essentially anyone could bid, I fail so see how the end result is all that different from these thieves selling them on a black market.

Sure, with an open auction there is at least a track record, of where these works end ended up. But access to these works would just as well be on the whims of private owners. To me it sounds like works of such cultural/historical value ending up in private hands either way, is the real crime here.

Maybe fully legal(ized) in one case, but I think that says rather a lot about the system as a whole.
>At the start of the pipeline we can afford to run lots of memory-cheap filters in parallel. Only a subset of incoming packets make it past these filters, so we need less of the more memory intensive filters running in parallel behind them to achieve the desired line rate.

What would happen if you manufactured lots of packets to trigger the expensive filters?
Ads serve several functions:

1. Inform the consumer that certain offering exists. If someone invents a new superior type of coffee maker, they should let people know that there's now an option to make their coffee in a better way. There's nothing unethical in that. Of course, you can invent something like cigarettes, which people would be better without, but most inventions aren't like that.

2. Inform consumer that certain provider exists. I.e. if you have 20 coffee maker vendors, all alike, then when a customer goes to buy a coffee maker, they would tend to choose one they heard something good about, thus brand promotion and celebrity endorsements. This _might_ be somewhat unethical if inferior product is promoted with superior ones available, but usually there is enough offerings of similar quality that this is pretty neutral. Sometimes also something good comes out of it when companies sponsor worthy causes to get attention.

3. Associate the offering in consumer's mind with something positive and desirable. This one may be the ethically questionable one, as usually the association is completely bogus and is not based on any actual qualities of the offering but only on unsubstantiated claims of the advertiser that consuming the offering makes the customer "a kind of person" they want themselves to be. This is the kind that gives advertising the bad rep. But most online ads are actually not of this kind - it's just much harder to make such kinds of ads as a small banner.
DJI Mini 2 review: The best drone for most people