skysight-inc/HackerNews huggingface dataset:
Because it degrades at higher temperatures.

They do stability studies on these molecules, holding samples at different temperatures and measuring how much "is left" after a period of time.

This particular RNA sequence and carrier might be particularly unstable, so it require -80C if you want it to last longer than a few weeks.
People often brag about "advanced" features of vim or emacs like you do, but everything you say is pretty standard these days. Vscode does the same. So does Intellij.
Thank you for sharing, i will check
But that's the democrat narrative as of a week ago: vaccine by EOY is too dangerous. Suddenly, a week later the same exact vaccine is perfectly OK and it's a scientific triumph. Is the attention span of the public _this_ short?
This in itself is not a tax dodge but if he wanted to this would set him up to be able to renounce his US citizenship and still have a good passport much like Edwardo Saverin and others.
To add: I dont know what the solution to this is. So lets say there are two types of approaching math. Approach one is formal/rigid (caring about Axiom of Choice, Set theoretical foundations ..:-)) the other one still (partially) rigorous but more classical in spirit. A big question for me is, how is actually research done? Is it more the first or more the second approach?
So what are possible solutions? I dont know. If you are trained in the first approach, you usually loose the ability to gloss over the gaps in the second approach. If you are trained in the second you cannot (or very difficult) come around the first one.

And then there is physics which uses the sloppy (and often not correct) version of the second approach. I once asked Serge Lang about this (phrasing:'what about physicist getting the right result with wrong mathematics' (thinking about renormalization)). Lang replied:'this is God's way of calculation'.
I do not believe that it's "morally acceptable." I believe that it is where the world is going. America is fracturing itself while China just keeps executing. Our bridges and electrical grid and transit systems rot into oblivion while people riot in the streets against their political opponents. While China is building up its hard power, soft power, and economic force projection with the Belt and Road initiative.

Was a incalculably powerful US that toppled democratically elected regimes in Latin America/Iran/etc. a morally acceptable one? No but that's what it is and all you other fucks had to learn English to get some of our money. Now the shoe is on the other foot and we are the fucks who will need to learn Chinese. Serves us right but I still ain't happy about it.
> If we could get high compliance

For better or worse [1], complying with mass government orders is simply not part of the collective American psyche.

1. it still remains to be seen if this individualism and distrust of government is one of America’s greatest strengths, or its future downfall
> Meanwhile, Selenium’s standalone Chromium image is 348.1 MB compressed.

Selenium implies you have quite a bit of a developer stack, runtimes and SDKs installed too. It would be unfair to attribute all that usage to Chrome alone.
If your finances are not in order, you can't be worrying about sustainability of some library or tool, or the industry for that matter. The industry is made out of people. If there are individuals who have to slave away to maintain an important tool or library, it's not going to be sustainable either.
I'm highly skeptical. Needing -80C is a major disadvantage. Pfizer would have collected stability data at higher temperatures if they could get it.

The fact it's -80C means they can't prove it stable at higher temperatures.
Dark Mode Userstyle for Techmeme
I just wanted to read in peace
Thee are other reasons to move local than hiding money, Cyprus is famous for agreeable estate tax. Seems a likely candidate given Eric Schmidt's age.
you either sell a service or a product, and must brand it as such.
IF you sell a product you lose all rights to modify, restrict and do anything with the copy you sold.

Open sourcing sunsetted projects, seems like a really sane approach - because lets face it - it can, and is, used as a form of planned obsolescence.
I read Whiplash by Joi Ito and Jeff Howe (MITP), in which Joi talked about "demo or die", and credited Nicholas Negroponte as the source of that phrase, but apparently not:
NN - "Somebody else actually coined the term “demo or die” and I am not sure who. It might’ve been Muriel Cooper, because I arrived one day at her lab and saw it written on a wall clock where all the numbers had been taken out and were replaced with the letters, “demo or die.” I thought it was pretty good." (https://www.wired.com/beyond-the-beyond/2019/05/nicholas-neg...)
Halal meat in Europe is stunned, only Kosher meat can’t be stunned. The only difference between halal and most modern methods is the blessing.
What's to stop the "tiktok kids" as I believe the new technical army is called, to go and get accounts on it and turn it into a new proud boys Facebook group?
Having a foreign citizenship doesn't change your ability to use international structures to reduce your taxes unless you give up your US citizenship.

It is possible to use such structures in some cases without needing to give up your US citizenship.

But there are plenty of non-tax reasons to get a second citizenship.
Ask HN: How much privacy do you lose with Google corporate accounts?
Recently after adding my workplace google corporate account to my phone it automatically installed meet, slack and few other apps. Also having a password is mandatory obviously for security.My primary concern is even to use gmail service on any android device you have to add the account itself to your phone which again invites all the policies set by the corporate to be applied on your phone.What do you guys think about this? And how do you manage your corporate accounts on your personal devices?
The US has an unsinkable aircraft carrier. The only way China gets the SCS is if the US withdraws.
Agreed, I trained a 3D version of b0-b2 on a classification task I worked on and besides being very slow to train they did not outperform a simple baseline VGG architecture. Interestingly training time was much improved by setting the cudnn benchmark flags in pytorch. Haven’t seen this reduction in training time for any other architecture but for b2 it went from about 12 sec per iteration to about 0.8. I guess there is more margin optimizing NAS models.
This is pretty much it. The Viking raids were, mostly, a way of obtaining loot and thralls, and it gave the peasantry an opportunity to attain an otherwise unattainable amount of wealth, and a way to Valhalla if things went wrong.
why does the vendor matter? The core problem is a dependence on ANY cloud, or any internet service.
I'm fully aware of what happens in slaughterhouses. I would be more than willing to pay for more expensive meat where the animals have more space for them, or eat proper grass, as opposed to, let's say, having corn shoved into them and antibiotics to suppress persistent infections, etc. The meat is tastier that way, too.

> you're just a sociopath

Sure, according to your definition I would be. So would most people, billions of them.

> Do you also believe it is okay for me to torture a dog just because I get visual satisfaction from it?

Visual satisfaction? No. But if you want to slaughter and eat it I don't have a problem with that.

> really? lol ok

Yes, really. You come across as some sort of quixotean person yelling at windmills while most of us over here are just eating our meat. It's simply that people don't say it, out of politeness.
Interesting. Figuring out the phase problem is one of my biggest TODO items.

How did you compute FFT of the phase? The thing is, phase is discontinuous or multivalued function if we represent phase as a real number. We could also represent phase as a complex number of unit magnitude: exp(i phi). It would be continuous, but complex-valued.

And phase is indeed important for hearing:

https://auditoryneuroscience.com/vocalizations-speech/speech...

I didn't quite get the trick with uninterleaving the lines.
To build incentive-based economic protocol and application without coding
Hey everyone! I have tried some no code tools, like webflow, salesforce etc. I realize how important such a software is to people without a background in code. I try to make a new one that helping innovative minds build robust, scalable applications and protocols that apply multiple incentives and financial system infrastructures, as well as a solid foundation for parameterization and progressive decentralization in subsequent protocol development.

Generally speaking, you can develop a cross-border fintech service platform, a crowdfunding application, or an organization with a distributed decision system and it's not even required that you need to know how to write codes. These applications may be as small as a Decentralized operated project (DOP) that lasts for several days or even hours, or as large as platform that is constantly updated and operated by a team or company. To achieve these goals, I have one of our core technologies: Assetflow, the world's first visual programming language for asset programming.

I would like to call this platform : Reach, Looking for your suggestions! https://discord.gg/DZmm97tDmC
Electoral Maps of 2020 U.S. Presidential Election Results from Notable Media
Parler 'free speech' app tops charts in wake of Trump defeat
Also from the same article:

"However, actual evidence has shown that Inuit have a similar prevalence of coronary artery disease as non-Inuit populations and they have excessive mortality due to cerebrovascular strokes, with twice the risk to that of the North American population."

https://en.wikipedia.org/wiki/Inuit_cuisine#Nutrition
Reads like a summary of Disunited Nations's chapter on China haha.
That model uses a sealed lead acid battery. There’s a picture of it in one of the reviews (the product description doesn’t mention battery technology).
I see no problem in challenging cultural/religious norms and traditions if the argument is made in good faith, and I have no reason to believe the poster was acting from a position of bad faith.

We can then decide if the argument is sound and we agree with it, or disagree with it.

There are plenty of such customs and norms I disagree with myself, for example the catholic ban on divorce (at least they do not excommunicate divorcees anymore; banned in the Philippines for anybody except Muslims), their ban on contraceptives in particular condoms (see: HIV), their ban of abortions ([1]) or their stance on gay rights. I think I have good reasons to disagree and that every example I listed has real world implications negatively affecting people and not just because they chose to follow Catholic norms.

Do I feel I am persecuting the Catholic Church? No.

[1] https://en.wikipedia.org/wiki/Death_of_Savita_Halappanavar
> Scala is a beast and the package manager + build tools were giving me headaches.

Ignore them and use maven. It's much better documented, consistent, and backwards-compatible. I struggle to understand why SBT ever gained any popularity, and it should certainly have never been recommended to newcomers.
The anti-pattern of front-end developers inferring design rules from mockups
> Law enforcement and judicial authorities must be able to access data in a lawful and targeted manner

The EU can certainly state this but I don't see why it must necessarily be true. One thought experiment to consider is if future technologies can read our private thoughts. The question to ask is whether access to these thoughts is allowed "in a lawful and targeted manner" as well. I'm not convinced that is afforded them against our will.
Maybe Newton spoke English, but didnt he publish in Latin?
Yes and no. US taxes favor certain types of wealth accumulation and wealth accumulation over income. But US taxes aren't particularly good to the rich, certainly not by global standards and certainly not in many states.

There absolutely are sophisticated tax structures both domestically and internationally that do require a certain degree of scale to benefit from them, though past a certain point make less sense.
Personal experience:
I came to like mathematics by way of computer science: so first got an understanding and appreciation for discrete maths, logic, etc, and only later on analysis and “phyisics” related mathematics.
It's hard to say exactly why, but I'd wager it's the following: discrete maths is easy to formalize and axiomatize for first year student, so you quickly get a grasp of the “rules of the game”: what axioms you're allowed to use, how an argument works, etc.
On the contrary, when you learn first year analysis, you see all those theorems talking about this (intuitively very simple but) quite complex object – the reals – of which you don't know the axioms (say linearly ordered field something something).
Thus, when you learn about the basics results, you're faced with a kind of two-faced problem: on the one hand, all the basic results are intuitively obvious, while on the other, you have no idea how to build a proof because you don't know what facts you can safely use.

I don't really know how to phrase all that, but discarding the CS/axiomatic side of maths while praising the intuitive physics-inspired one is not the right approach imo.
> isolating the effect of letting the chickens run around

true but irrelevant. What you said earlier was about 'pasture raised'...

> factory-farmed meat being less nutritionally dense than pasture-raised meat

but they got the same nutrition because they were fed the same factory diet, free-range or not. So totally irrelevant.

> and you are refuting with zero evidence

No, you are claiming with zero evidence. I am asking for evidence, and then point out your one piece of subsequently cited 'evidence' wasn't.

Your next cite is pretty ambiguous too - you previously: "and poor diet makes most factory-farmed meat less nutritionally dense than the pasture-raised", your cited study:

> It is also noted that grain-fed beef consumers may achieve similar intakes of both n-3 and CLA through the consumption of higher fat grain-fed portions

So in that respect the same.

Looking at https://en.wikipedia.org/wiki/Glutathione for example says "Systemic bioavailability of orally consumed glutathione is poor because..." so that don't help, and I can't see any evidence for or against that glutathione (or the other antioxidant) survives cooking.

Your posting unsubstantiated stuff is no more than an extension of ant-vaxxer's thinking, "this is fluffy and nice so it must be right".

Reality matters. What you want to believe doesn't.
Brazil suspends trials of China's Covid vaccine, citing 'serious adverse event'
That's a hell of a claim I'd be curious to see backed up. In a sense, one of the first tests for a funded founder is hiring folks at below-market (my initial 50% estimate) who still outperform others.
If it's done, it will allow cracking software that uses basic protection methods for $10 flat.

But for the normal use both the pricing and its off-prem nature renders the whole thing all but useless. A pity really, because the tech looks fantastic.
Can you explain why? Reading their official website, I can't figure out what it does or what it looks like.
FATCA doesn't create tax obligations it has nothing intrinsically to do with tax it has to do with financial transparency, which yes can help to catch people who are evading tax but if you're structuring your affairs legally FATCA has no impact on your taxes.
Nah, America was losing Vietnam. It couldn't be won the way it was fought. That country is no slouch. Within three decades they fought off three world superpowers. Veteran soldiers, local knowledge, sympathetic populace, terrain advantage.

None of America's aims could have been achieved there meaningfully.

Big guys lose to small guys all the time. Sometimes you've got to know how much it's worth risking. Britain was a world hegemon. Still lost to an upstart collection of colonies.
> Who here can visualize an apple in their mind, literally seeing it as if existed and was being perceived by the eye (a sense organ)?

Anybody who dreams when sleeping. Is that not everybody ? Ability to do it when awake (lucid dreaming) is a different thing.

> lack of awareness equals lack of consciousness

No it does not. I'd argue that even deep sleep or getting knocked out does not equal loss of consciousness. We can't tell, as consciousness is only perceived through it's contents, so we can't distinguish between absence of contents or absence of container.

> Leave them closed long enough and you will lose what we are seeking to define here.

Consciousness is not the model. It's where the model is built. You only mention perceptions, what about thoughts ?
Oh I've seen plenty of pictures and videos and whatnot. I've slaughtered plenty of animals myself (though never a cow, to be honest).

I'm not looking away and pretending it doesn't exist. I'm staring at it and saying "yes I approve of that because I like to eat animals".

If your argument is that intensive farming is less than ideal, sure, I agree. If your argument is that the solution to that is to stop eating meat, that's where you lose me.
Amazing name. Has my Latin nerd stamp of approval.
HAha what, Pizza is meant to be soggy?

I guess I'm a great chef then!
I got caught up in all his videos and had the same question. Fortunately, he has a dedicated video where he answers this with testing on the scope: https://www.youtube.com/watch?v=fCbAafKLqC8

tl;dr is what the sibling comment already explained: low clock rates.
> been working my way down Youtube videos. ... If you don't pay for this video, then either there is no video, or advertisers pay

Youtube Premium which helps pay for videos is right here:

https://www.youtube.com/premium
Looks nice. Do you have plans to allow it to implement nicely with grid frameworks such as Ag Grid, Kendo etc?
I think it's a part of a bigger problem I see. People are hung up on where they want to work. If you HAVE TO work for certain companies, and you want your finances in order, you're doing it wrong. Priorities!

Also, you don't need most companies or all companies to value your open source project. You need one.
That's not how vaccines and viruses work.

Normally when you get infected you get small number of viral particles in your system. Those then hijack your system to create more, and those new particles spread to other people through sneezing etc. In time your immune system learns how to recognise and kill the virus and eventually removes it from your system.

Now let's say you get vaccinated and you get that same small number of viral particles in your system. Your immune system will already know how to recognise and kill the virus, and immediately starts doing this. It doesn't multiply in your body, so it can't spread to others either.
YSFlight HQ: “START HERE – What you need to know”
The same applied to an armoured knight, but it's hard to trap a mounted warrior when you're on foot, just as it would be hard to get a tank stuck unless you know what you're doing.

I'm certain that more than one knight died locked inside a burning barn back in the days.
I feel like this is an underrated sentiment. A lot of Rust’s design decisions (lack of inheritance, borrow checking, immutability by default) are complete non-issues when you’re reading a JSON string into some business struct or an enum and then serializing it back out to a DB again. Everything can be flat data types and functions can be pure and stateless.

But not if you actually have to keep things around in-memory. Then all the sudden your functions can’t be pure, you have to add additional parameters to each method to account for additional state, and you can’t design flat structs anymore since you have many different object types and they have to go somewhere and you can’t just declare N variables line by line. So you have to grapple with the limited definition of trait objects, or non-extensible enums, or throw everything out and use Any. It gets complicated.
Let me try to steelman it for you: unless we assume God exists in the particular way a given religion says, religion dogma makes a debate around ethical animal slaughtering too inflexible. It is highly unlikely that either kosher or halal rites maximize ethical treatment beyond any chance of improvement (unless you assume divine guidance, obviously), and neither religion is very open to revisit dogma at the pace that ethical understanding of how animals ought to be treated, outside of a religious framework, evolves. Thus, we can consider religious views here as roadblocks.
Calculations are based on memory but everything else not so much in my opinion. Sure, some methods for solving common problems are memorized
I fail to see how you're not just waving hands. You assume that consciousness is an emergent property of matter, you think it's plausible, but you can't explain it or prove it.
Show HN: Emojeet, Twitter-like but only with emojis
Crimea is too important for Russia to realistically expect it to continue being Ukraine territory. They let it be while Ukraine was pro-Russia, but everyone who understood how things work, was sure that Russia would take it back immediately if Ukraine ever turns to NATO. I'm actually surprised that it took over 20 years to happen. Russia needs to control black sea to survive. And I think that in the end it was a good outcome. No blood was spit. Population in Crimea is Russian, despite what you might hear from western propaganda, the majority really voted for Russia in 2014 referendum and happy with the outcome.

Other than Crimea, Russia did not get any new lands. I think that in the future they'll join eastern parts of Ukraine and it's also likely that Belarus will join Russia, but for now I don't think that there are any more serious claims. Of course Russia will continue proxy wars and support pro-Russian countries, just like any other major power does.
Yeah it's cheesy but it's quite accurate that it shows how hard it is to kill someone clad in chain mail and full armour. The bandits are not very well trained although they do try to stab between the plates bit it's still very difficult to do.

Also the guys doing the videos are re enactment pros and yes what they do is a bit theatrical, but other YouTubers specialising in this area have said it's quite legit. I'll link to video when I have a chance
Were you trying to put forth an argument? Because I don't think you did.
I don't know if ESTA is still involved, he explicitly said his ESTA applications were denied in 2017 and that's why he applied for a "tourist visa" and I don't think ESTA applies to that in any way. But he's a smart enough guy to read the limitations of tourist visa, I wish him the best and I hope I'm wrong.
Another major difference between nation-building in Germany post-WW2 and nation-building in Iraq post-Saddam was that the occupying forces (mostly the Americans) left most of the Nazis in place (with a few notable exceptions at the top), while in Iraq almost the entire Baath Party structure was obliterated.

One of my favourite examples is Hans Speidel [1], a Wehrmacht lieutenant-general by the time the war ended, who got to be "Commander-in-Chief of the Allied Land Forces Central Europe from 1957 to 1963", plus the major shareholder of Mercedes in the 1960s who had been a big Nazi sympathiser during the war (his name escapes me right now, and I can't google him easily, the official Mercedes history does not mention him), to say northing of how the infamous IG Farben was split between BASF and Bayer (among others), and not immediately raised to the ground and liquidated. I don't think the Americans that occupied Iraq in 2003 were as friendly with the company that stood behind Saddam's chemical attacks against the Kurds in the 1980s.

[1] https://en.wikipedia.org/wiki/Hans_Speidel