skysight-inc/HackerNews huggingface dataset:
Folding@home https://en.wikipedia.org/wiki/Folding@home :

> Folding@home (FAH or F@h) is a distributed computing project aimed to help scientists develop new therapeutics to a variety of diseases by the means of simulating protein dynamics. This includes the process of protein folding and the movements of proteins, and is reliant on the simulations run on the volunteers' personal computers.

"AlphaFold: Using AI for scientific discovery" (2020) https://deepmind.com/blog/article/AlphaFold-Using-AI-for-sci...

https://www.kdnuggets.com/2019/07/deepmind-protein-folding-u... :

> At last year’s Critical Assessment of protein Structure Prediction competition (CASP13), researchers from DeepMind made headlines by taking the top position in the free modeling category by a considerable margin, essentially doubling the rate of progress in CASP predictions of recent competitions. This is impressive, and a surprising result in the same vein as if a molecular biology lab with no previous involvement in deep learning were to solidly trounce experienced practitioners at modern machine learning benchmarks.

Citations of "Resource-efficient quantum algorithm for protein folding" (2019)
https://scholar.google.com/scholar?cites=1037213034434902738...

Protein folding: https://en.wikipedia.org/wiki/Protein_folding
That's super cool, I never knew this but I always thought that it was very similar to Buildcraft.
As of the first graph in this August 2018 blog post [0], it seems like Google's Public DNS was handling about 14-18M QPS (1.2-1.6T per day).

[0] https://security.googleblog.com/2018/08/google-public-dns-tu...
This reminds me that I should setup a proper captive portal for my family’s restaurant.
GDPR doesn't apply to this storage of data since it's regulatory. Besides, these services are all-inclusive, you're sold a GDPR-compliant solution.
I don't see it as Kubernetes being the common interface but containers.

So long as an organization uses a container-first philosophy or container-centric workflows for development they can deploy to pretty much anywhere.

Kubernetes gets the buzz but containers are the real key to flexibility.
> Key apps have zero incentive to try to get people to switch to Android.

Google Play is less stringent about privacy than Apple (right?), so the same incentives would exist.

> Even if there was, there is a prisoners dilemma - it would only work if many of them switched at once.

Which would still be true with alternate stores. Nobody wants to be the first to switch to a shady store that customers don't trust and abandon the one they do.

> Most users do not refuse to use Facebook. New people take up smoking daily. The idea that users would ‘refuse’ to buy apps from a store run by Facebook (or worse) is an idealistic fantasy.

Then what's stopping them all from switching to Android right now? Why haven't they done it already?

> As for why apps would switch to other stores? Paid exclusives, just as with every other media type - TV, Movies, Books, Podcasts.

That only gets the user to use the store to install one app which they're already familiar with. It doesn't require anyone to trust the same store for apps they're not familiar with. For that to happen the store would still have to establish a reputation for trustworthiness, which would require it to not carry shady apps.

> The only choice for users would be to install all of the stores.

> The only choice for developers will be to deal with all of the stores.

These are obviously contradictory positions. If all the apps were in all the stores, a user would only need to use one of them (presumably the one they like the best). If all the users had all the stores, a developer would only need to be in one of them (presumably the one users like the best, to maximize competitive advantage over alternative apps).

The stores still have to compete with each other for users.

None of your conclusions make any sense. Competition reduces costs because all else equal people will choose the alternative which takes a smaller profit margin and passes that money to the user or the app developer, which either makes apps less expensive for the same amount of developer revenue, or increases developer revenue at the same price to the user which leads to more and better apps.

Monopolies are abusive and inefficient, so removing them makes things better. It's why we have antitrust laws.
I think the actual best course of action in general is to deport the rich that cheat on taxes and let them go enjoy being rich in some other country, or in international waters. The idea that we should tolerate big parasites because they'd take their money elsewhere both undervalues everything else about a region and it's people that might keep them there and overestimates the value of being home to greedy wealth.

It's stupid to play in the race to the bottom of governing power versus concentrated wealth. It's something captured/self-interested regulators do, not honest ones.
https://www.youtube.com/watch?v=52XlyMbxxh8
I remember him specifically saying he thought spying on allies was wrong, and even a key component of his decision. Whether you agree this is the deciding point for crime / not crime, it is certainly a division between blowing whistle on domestic spying and everything else.
> it's a lot safer than many sports and hobbies.

What is the basis for this claim? How do we measure mental injury? What quantities are we talking about?
As an adult with ADD i cast doubts about the diagnosis. I have started to more and more think my diagosis is just a result of not being a high productive high intelligence individual.

I more and more realise that my brain and personality is not the kind that is made for desk work. I find it boring and difficult.

I have done other types of works that suits me better i beleive my life would be so much better if i just accepted that i was never to be sitting at a desk solving problems.

School has always been difficult for me, simply because it hard to learn the things you need to learn in shcool, for more intelligent individuals school is not the same big deal as it is for me. But thats just the way things is. The same way i was not born 2meter tall and an musculuar body.

I beleive that we will see more and more ADD/ADHD diagnosies in the future, simply because automation puts more demands on the individual and the jobs will be more mentally demanding.

I see a future where meds like adderal will be availble in the supermarkets.

Instead of giving people ADD/ADHD diagnosises we should just teach people to accept that not everyone are made for mentally demanding tasks and that not everyone goes thru school without it being a huge difficult task. Parents also needs to learn that their kids might not will be able to compete in the job markets in the future and the solution is not to medicate it away.
Why not? 99% of the things Greenwald et al published from his leaks were perfectly legal, and that was just a small subset of the total documents Snowden leaked. Why not just expose the illegal phone metadata program? If he had done that, he would easily qualify as a whistleblower.
My background in software hacking, from 20 years ago, was all remotely working with other people over text. So working from home always feels natural and productive to me. I'm able to think better this way than in person with physical distractions and having to talk in realtime rather than thinking carefully about each thing I say.
I think he's a little too focused on the paper-publishing aspect, but that may be just his specific corner of the world, and his experience. It might have been that in his sub-field, that seemed to be the main way to make impact.

I think the point is, if you want to be successful in academia, you need to be producing something theoretical or practical that others can consume and find useful. The medium need not be papers. It could be:

-- standards

-- methodologies

-- prototypes

-- libraries of code, manuals of protocols

even more practical things:

-- convening people on a topic with authority

-- writing popular works to publicize the field

-- building a scientific facility

-- even TV shows or blog posts

You will find professors at universities who do a whole variety of these kinds of things, not just publish research papers.
(and as they get more senior, they often find more interesting outlets for their work, if they're innovative)

But you have to make something that others (in the scientific or industrial or popular community) can consume. All the paper counts in the world will not help, or make you satisfied, if they're just churned out for the goal of increasing your H-index but don't actually contain something wanted by others. It usually doesn't work as an approach.

If you can't do any of these, then you are probably better off taking a normal job. The incentives of academia will not align with your talents.

Personally, for example, I found that the things I was good at publishing or sharing with others wasn't groundbreaking novel research. So I went where that was valued, and have been happier since.
Yes. But do you need to market that to anybody with a headache?
> What if they got a request like this from someone who claimed not to have access to the email they used to sign up? HN couldn't possibly comply

They wouldn't have to. If you're requesting your data from a company, you have to burden of proof that you are in fact the person about whom you're requesting the data. If you cannot prove it, you cannot get the data.
The Sacklers should definitely be in jail. But everyone in the value chain is culpable. Why did insurance pay for these for almost anyone? Why did doctors prescribe it so liberally? What about the med reps that (until recently) basically all but bribed doctors to push their new drugs? What about the FDA and monitoring the quantity and velocity of these prescriptions?

It used to be that, outside of the hospital, people only got morphine at end of life. What did we think would happen when we started handling them out like Skittles?
Ask HN: ReactJS component library for making games?
Hi HNers! Does anyone know if there is a component library for React that has all the common elements found in games? I am a web person who has built information-driven apps and sites for a long time, and am a little overwhelmed by the thought of building loops, and stages, and worlds, and ka-ching moments, etc. from scratch. Just like component libraries not only made it easy to not write repeatable code but also encapsulated industry patterns in easy-to-import components, I was wondering if there is an equivalent for building simple web games that I could use.
Living in this particular french city, I actually need these WiFi access to work, be it logged or not. Many independent workers resort to bars and café as cheap coworking space and this may just going to lead owners to stop offering WiFi (which is often quite necessary). SO again I'm not sure why this one city is targetted but surely it has to do with he recent feud with the ministry and the city mayor.
Thats true for the senate, but that’s why there is another branch that has proportionate representation. Both of them have important individual roles that the other branch would/could not do, due to political barriers.
https://archive.is/TsNvF
“It is difficult to get a man to understand something, when his salary depends on his not understanding it.”

― Upton Sinclair, I, Candidate for Governor: And How I Got Licked
it's definitely possible that individuals using these drugs carefully and deliberately could discover some kind of valuable practice or insight. And perhaps this could turn into something that eventually could be shared among many people, with the right context, like the Eleusinian Mysteries or something.

if people want to do this it seems like a good thing, if risky. (although there are people who claim to be using psychedelic drugs as a tool, but don't seem to be very disciplined and are really just enjoying recreational drug use -- which is probably safe but also not particularly valuable.)

what i find troubling is the idea that society would be better off right now in 2020 if most regular people just started taking mushrooms semi-regularly.
Tried out Red Hat 5 from a CD in 1997 on the family Pentium 75 MHz. Couldn't get internet to work so it didn't get much use. Later when I was studying in 2005 the computer room in the school had these insanely restricted Windows computers where the only browser was IE, sessions got wiped when logged out.. so burned Knoppix to a CD and later some other similar "portable" distro (don't remember its name, something starting with "S" I think) on USB with persistence. That lead me to install Ubuntu on my home computer and haven't looked back, unless you count the fact that I've been using MacOS since 2015, but I do manage a large amount of Linux server in my job.
Ion almost got it right. The problems are:

- Binary format is big endian. All modern processors use little endian.

- The time format doesn't have a time zone.

- The binary time format is in UTC, while the text format is in local time, and you have to convert (WTF!)

- The binary time format is HUGE.

- Typed nulls seems a little excessive for very little gain.

- No efficient small integer encoding.

- Containers in the binary format are prepended by the element count, which makes progressive container filling impossible.

- No custom types (except maybe s-exps, which are overkill)

- No metadata

- No URI, UUID types

- no markup container

- no references
> You might enjoy Jordan Peterson's take

I absolutely would not.
The ugly at universities is much worse than what was posted.

Athletes getting easy courses. People in power positions typically don’t deserve it but think they do. So, there are ridiculous projects, bias, and people getting paid in “non-standard” ways. Backroom deals with private industry and government. Things that would make no one want to go there.

Universities should work more with private industry like they used to many years ago, government money should be poured into research more openly, and tuition needs to rise, then they can hire the best from private industry that are also excellent teachers or researchers.

To do that, administrations and staff will need to be gutted.
> Refactoring shouldn't exist in this hypothetical game

Without refactoring the factory planning phase would be more difficult since I don't want to fill the best places on the map with unmaintainable, non scalable factories. Refactoring should be very easy, e.g. like in Factorio with construction bots: just press ctrl + x and the bad part of the factory is gone.

If you want to build an abomination, try SeaBlock mod [1] for Factorio. You don't have to refactor anything, space and resources are infinite, so just build a new factory next to the old one after you research a new tier of technology.

[1]: https://mods.factorio.com/mod/SeaBlock
> I actually tend toward the idea that people that manufacture and sell potentially harmful, but inanimate things are in no way responsible for their final use (or misuse). They're not forcing anyone to take these drugs, nor is the prescriber, nor is the pharmacist, nor is the truck driver who drove it to the corner store.

This might be admissible in the case of the sacklers if all they did was create the drug and make it available, but they did much more than that: they marketed opiates heavily, they aggressively downplayed the negative affects, and they incentivized doctors to prescribe (which of course apportions some of the blame to the doctors as well).

And even the prescribing doctors share in the blame through their deliberate actions: first, when a doctor prescribes opiates, they’re not prescribing some other treatment, but you (the patient) still have the issue, so you can’t really not take the opiates, ie forego treatment, especially since you’re also out the money and using up your insurance (if you even have that!); second, not behaving in line with your doctor’s wishes can have its own set of consequences, ranging from ticking your doctor off (which is bad, since you need them to help you with your condition, and finding new doctors takes time and money, and you’re ill all the while) to getting sent to the psychiatrist.

So much to say, I think this attitude is incorrect in the case of the Sacklers, as it doesn’t comport with the evidence, and in the general case it’s naive.
Magic Wand Rechargeable Teardown
In many countries people eat young lamb or veal, some consider it acceptable and others don't.

It is very easy to call for a ban on something that you personally do not enjoy because you lose nothing. In fact a majority of the world's population likely does not enjoy cruising, just as a different majority does not enjoy snow sports, water sports, car racing, motorcycles, horse racing, skydiving, rugby, rock climbing, etc..

There is some form of ethical or safety concerns for each of those but the world would be a very boring place if we banned them all.
Citations? The point of my comment is I would love some facts to back up this ‘known’ story.
Would be good if the website would feature a description and screenshots when accessing it on mobile.
It just means that they didn’t find useful network structures with the specific network analysis methods they used and the specific networks that they constructed using the data.

It leaves room for tons of other network analysis and data analysis.
Iraq was about securing the US Dollar as the reserve currency for trading oil, not about securing supply to Western Europe. Saddam was threatening to start trading in Euros - he wasn't threatening to cut them off.
Regarding #2, would you really be ok with loading half a configuration file? Or am I misunderstanding your point?
"But after all, it’s the leaders of the country who determine the policy, and it’s always a simple matter to drag the people along whether it’s a democracy, a fascist dictatorship, or a parliament, or a communist dictatorship. Voice or no voice, the people can always be brought to the bidding of the leaders. That is easy. All you have to do is tell them [you] they are being attacked [by Russia], and denounce the pacifists [Snowden] for lack of patriotism, and exposing the country to greater danger."

- Herman Goering [with additions]

Nothing much changes.
Rural/suburban folks tend to own homes, and property owners vote more than renters do.
We’re long past tax revenues defining government spending. Deficits are abound even in good times.
Swartz participated in the creation of RSS spec, not JSON AFAIK. He was also involved in the development of reddit.
It's not bad, it's just that if you were able to do this then you would not reproduce and would remove your contribution to the genetics (and to a lesser degree, memetics) of future generations.
Man, this is the french justice system, not the US. Jury trial (assises) doesn't happen for anything short of blood crimes.

On the other hand, plea deals are not a thing either, so if the state decides to press charges, you're definitely going to see a judge.
> From what I've read, Oxycontin was the first available drug that could be easily administered at home once or twice a day

There are other opioids with extended release formulas, including morphine - they are nothing new.

One of the major problems with OxyContin was that they lied about how long the effects lasted. From memory, they claimed up to 12 hours, and insisted you shouldn't take it more than twice a day. This turned out to be BS, with patients reporting it lasted for 6-8 hours max - just the same as other extended-release opioid formulations.
I didn't know that ham radio was allowed to use proprietary protocols.
Is the only allowable statement one that can be backed by quantifiable analysis?

I didn't even specify which hobby, so lets go with alpine mountaineering. Hard to be more dangerous than this. Gridiron football has some good quantification, with ways of measuring mental injuries.

sheesh.
>The fact remains that the ultimate responsibility for what goes into the body of a functioning adult who is not coerced in any way lies solely with that adult.

This is horseshit sneak. You know it's horseshit. You're on HN, you deal with tech all the time. Would you say that responsibility for any security flaws or leaks in software lies solely with the "functioning adult who is not coerced in any way to install it"? Individually we're humans, we have fixed brain size and thermodynamics and thus have hard absolute limits on the total amount of information we can ever know and much much tighter limits on the rate at which we can ingest new information, process it, or make decisions. It is impossible for a human brain to be in charge of everything in modern society. IMPOSSIBLE. There is not enough time in a day, not enough days in a lifetime, to learn more than the tiniest fraction of what all of us use constantly. We deal with that by massively externalizing onto other people/organizations and trust frameworks, and then working to ensure there can be enough confidence in those.

So responsibility is absolutely a spectrum, in medicine, in tech, everywhere. We cannot verify it all ourselves. Something must involve external relationships, and those external relationships are themselves two way aren't they? In a relationship, BOTH sides have responsibilities.

>We fault the individual when they don't take their medicine. Why do we fault their physician when they do?

Um, because it's a two-way relationship? The patient's part of it is to seek external expertise, and then follow through on expert instructions. The medical expert's part of it is to faithfully give instructions that are wholly in the patient's best interests to the best of their knowledge and capability, without any self-interest beyond the remuneration the patient offers for said service.

>Your doctor is NOT the authority on what goes into your body: you are.

As vacuous as claiming car manufacturers are not the authority on what you drive or it should be fine for food/medicine/anything manufacturers to lie about what goes into their products because hey, your fault for not verifying it. No, that's not how any of this works.
In search of lost teams: why teams fail, and how to fix them
Many local US governments establish prevailing wage-laws that set minimum wages for construction jobs that private contractors have to abide by if they go work for the government.

https://secure.lni.wa.gov/wagelookup/ApprenticeWageLookup.as...
I'm not sure, sorry. I'm not honestly sure why there's so much discussion about security clearances.

If someone gets your grindr account they can get your (a) address, (b) phone number, and (c) private photos, none of which would otherwise be public. So let's just get that out there. A reasonable user would not expect that any of those three things are readily available to a stranger that they've never talked to who merely has their email address. Especially if they turn off distances specifically to avoid triangulation attacks on their location.

Those pieces of information can be used together to harrass, commit violence, or threaten to leak your photos or personal (albeit sure, not "private") conversations. Those are the obvious ones, but other information in there can also hidden from public view, like HIV status.

With this bug a malicious person could knowingly target you based on email address instead of finding you and even putting the work into catfishing you into sending them embarrassing photos.

I'd say that's a higher blackmail risk but only because of the hack, a little. Catfishes still existed but this makes doing it invisible and massive in scale while associating it with a public ID like your email address.
So I guess my interpretation wasn't that far off then. You actually were suggesting that girls had more potential.

Well, since you also make clear that you believe such a thing only because you choose to and without evidence, I guess there's really no point in discussing it. All I can say is that I disagree, entirely, and this article (and many others with similar findings) are more than enough reason why.