skysight-inc/HackerNews huggingface dataset:
> rather than producing them outside the body and then injecting them

That's not what the Oxford/AZ vaccine does, is it? From what I understand, it's a viral vector vaccine engineered to deliver DNA that encodes the SARS-CoV-2 spike protein into human cells and induce them to express the protein, stimulating the immune response.

The plan was never to introduce spike protein "produced outside the body." The mechanism of action is getting the body to produce spike protein and learn to attack it as foreign. If the Oxford/AZ vaccine doesn't "take advantage of your own cells to produce the spike protein," I don't know what does.

https://labblog.uofmhealth.org/rounds/top-5-covid-19-vaccine...
This seems to imply unfounded causality placing the blame at the feet of America. If ISIS wasn't fought then there would have been millions of people displaced all the same. There has been a decades long ongoing civil war in Somalia. There's nothing which suggests that things would be peaches and roses in Somalia if only the US hadn't been fighting Al-Shabaab and Al-Qaeda there. If anything there could have been greater displacement of people fleeing the more successful and bolder Islamist forces.
> But then we use that drinking-level standard water to (1) water our landscape and (2) flush the toilet.

Doing otherwise would require a massive duplicate water distribution network for non-drinkable water.

> There's a community outside of Taos, NM that experiments with what are called earthship designs. (There are actual people living for years inside these earthships). These earthships are designed so that waste water cycles through the system three times before feeding a leach field, using landscaping plants to clean the waste (carbon cycle). By that I mean, clean water for drinking and washing gets reused as grey water, cleaned by plants, and then reused as toilet flushing water.

There are more scaleable to recycle water, but I am generally in favour of the concept.

> That integrated greenhouse is also a part of a passive heating and cooling system that keeps the inner environment a comfortable 70 - 80 degrees, with vents that can adjust the temperature. It maintains that temperature range in a high desert. In addition to temperature regulation, greenhouse provides supplemental food, part of the water purifications system.

That sounds labour intensive and non-scalable. How big would this green house/ water recycling solution need to be to power a single apartment building? How many people would be required to keep it up and running? What’s keeping this green house warm?

> Our medical system is very good at treating acute problems, but very poor at treating chronic issues. It is generally not holistic, and there are blinders in the paradigms that prevent researchers from looking into effective treatments. Furthermore, in the US, medical care is in a runaway feedback loop between insurers and providers, significantly increasing costs

I wouldn’t use the American system as a basis for a critique of modern medicine. Every other developed country is able to avoid the mess you described.

> But the main thing is: sustainability is _not_ enough. That is essentially saying, "do less harm". Baked into that paradigm is that the harm from our current practices is inevitable, so we should strive to do the least amount of harm with that inevitability.
> Instead, we should be looking at regenerative practices, and one that is not anthropocentric. It requires a different way of seeing. We don't have to "regress". We can do a lot better.

You are going to have to be more concrete than that. Every living creature consumes resources from their environment and every creature will destroy their native environment unless held in check by predators or some other external limiting factor. Humans are the only animals to understand this, so we have the ability to moderate consumption.
I think school and day care are a reasonable assumption. It’s a bit unfair to say — _keep your spouse at home because there maybe once-in-a-lifetime pandemic and the schools will be closed_.
No, the AZN announcement was made after the market closed. Take for instance Moderna, who was -13% today, and is +3.7% after-hours
The one year old isn’t ready for overnights for a number of reasons.

I’m not saying we’re in dire straits here. Being a parent is the most fulfilling thing I’ve ever done. But it’s also the hardest job I’ve ever had. And you can’t wake up and decide to take a me day.
Depends on what you're letting past the firewall. Even ICMP requests could (not sure if this was ever patched) be used to DoS a Win95 machine. There are several open TCP/IP bugs with Win9x, the newest one being from 2008.
The Future Is Fungal: Why the 'Megascience' of Mycology Is on the Rise
I hate to judge a project by the technology choices but no SSL on the landing page and PHP is just the tip of the iceberg here.

- Every table uses MyISAM. Interesting choice, but maybe the fancy features of InnoDB aren't really needed.

- HTML in the database for storing page templates. The entire workflow in terms of HTML views of the application process are stored in the database. That's got to be rough to maintain. https://github.com/opencats/OpenCATS/blob/77c1f2bcf1bc92f4ca...

- Uses mcrypt (not for passwords), which is deprecated and also abandonware. https://github.com/opencats/OpenCATS/blob/77c1f2bcf1bc92f4ca...

- Passwords appear to be stored as md5 hashes. https://github.com/opencats/OpenCATS/blob/77c1f2bcf1bc92f4ca...

- Yep, md5. https://github.com/opencats/OpenCATS/blob/77c1f2bcf1bc92f4ca...
Making fsync a no-op and not having any durability at all is perfectly POSIX compliant. POSIX only concerns itself with the visibility of I/O in the live system (e.g. a process either sees a write fully realized, or not at all - this didn't use to be true for larger writes until fairly recently, btw.). POSIX specifies nothing about what happens when a system is restarted or looses power.
Nice but you guys might want to create a sort of ‘low-fi’ interface like this. It’s a ton easier on the eyes esp mobile and is a nice change from the typical news site.
Do we understand what the fundamental computational operation is in biology yet? Eg, in computers it's boolean logic, transistors with on/off gates, representing true/false or 1/0, from which all other more complex logical operations can be composed.

Does biology have an equivalent? Or is your comment essentially explaining that it probably does, but is more complex and we don't understand it yet?
new.reddit.com - 327 requests, 8mb, 7 seconds - https://tools.pingdom.com/#5d1bf3f952400000

news.ycombinator.com - 7 requests, 22kb, .125 seconds - https://tools.pingdom.com/#5d1bf4a4f8400000

The hilarous thing is that if you put in https://www.reddit.com to pingdom's measurement tool, reddit returns the old site layout. https://tools.pingdom.com/#5d1bf3c4e3800000

edit: Just poked around a bit to find best worst examples. Unsurprisingly CNN is the worst I could find after a few mins - https://tools.pingdom.com/#5d1bf596ffc00000 543(!) requests, 9mb, 6 seconds. Just stroll through the list of bullshit it sucks into the front page...what a mess.
I think you are on to something. Many people are happy to be generous with others time and money but less so with their own.
Correlation is not causation, but you didn't ask for proof, you asked for evidence, and correlation is evidence. For example, do you know whether smoking causes cancer? Because all the evidence we have that it does is based on correlation. Or you're happy saying "I don't know" and asking more questions? How would you show a causal link between vitamin D deficiency causing the evolution of light skin colour without being able to conduct a double blind study? It's fundamentally impossible to prove, all we have is evidence, which is this case is sufficient to say as the first sentence in Wikipedia [1]:
"An abundance of clinical and epidemiological evidence supports that light skin pigmentation developed due to the importance of maintaining vitamin D3 production in the skin"

[1] https://en.wikipedia.org/wiki/Light_skin#Evolution
You hit the nail on the head. Wealth isn’t about loving green pieces of paper. It’s about the freedom it provides. But from his place, he’s already doing exactly what he wants. There’s literally nothing he wants more than what he has. Now maybe that would change if his health is constrained, but as it stands he spends everyday exactly how he would spend his weekends if he was working at a 9-5.

That freedom of time is all that money can ultimately provide in the best sense. However, amassing wealth by moving away from that is definitely counter-productive. Wealth is just a means to an end; if the end is already at hand it provides little to no marginal utility.
> If anything, companies should be providing more childcare so that more women (as well as some men) will have less of a burden balancing career and caregiving.

I think this is the crux of the matter; some people think that companies should not be doing this, society as a whole should through the age-old custom of voting. My other comment [1] on this thread elaborates.

> It's similar to "I don't take the bus, why should my taxes pay for public transit."

The difference is that public transit is a public utility. Anyone can use it if they want to. This is more like your employer offering transit that only parents can use. Everyone else is excluded – people who need to be caregivers for a relative, people who are suffering from depression, people who can't drive, etc. Naturally some of the latter group will think “What's so special about the parents that my employer who is a private company is making special concessions for them even when society isn't?” My solution to this would be basically just that – to open up more flexible schedules in general, and ideally based on what society as a whole wants. Unfortunately, any kind of attempts to make corporations give employees more flexibility by law are a non-starter in the US, which means that US society as a whole doesn't buy into this “We're all in it together” paradigm.

[1] https://news.ycombinator.com/item?id=24414141
Yes, that's why I recently switched. Actually really unfortunate because now my texts take quite a bit longer and I lost $50 I'd spent on apps, but definitely the right choice.
I think that's different. Chaos still uses classical probability and the randomness is just ignorance of underlying initial conditions. This is very different from QM.
Had the same idea, but my OS is so uncommon that malware probably does not exist (if it's not a targeted attack).
FIXME: Security issue, this function is not enough for sanitizing user input.

Not off to a good start.
It's not fair to blame people for "choosing" to have children because, in the aggregate, the majority of people need to have children in order for society to survive. So it's not really a choice if a majority of people have to do it or everything goes to shit; it's more like volunteering to take on a necessary burden (that admittedly has its rewards too).

A better outcome here would've been if she hadn't needed to give up her job to have kids, like if there had been universal childcare and her work was more accommodating of mothers.

> $22000/yr is a lot for someone only making $75000.

If you think $53k is rough for one person to survive on, wait till you see how hard it is for two people to survive on $22k!
I agree with you. I was thinking about remote work in the long, but this was hidden in the last paragraph.

> However, if this arrangement is to last, then childless employees should also get time for their personal obligations, whatever they might be.
The difference is that the burden of taxes are distributed fairly (for the most part at least). If you need to pick up slack because your coworker is taking care of their kids, the burden is 100% yours. It would be like forcing you to foot your neighbor's cancer treatment.
It has been almost 7 years since the Xbox One launched...
https://en.wikipedia.org/wiki/Xbox_One

Console generations have generally averaged 7 years for quite a while now.
On the Ultrascale Zynq's you can build RAM that is attached to the fabric and available to the processor across the AMBA bus. It isn't something I personally have played with a whole bunch so I can't give you a better answer then to look at the Zynq data sheets.

I do know you can make user hardware "appear" as memory to the main CPU.
> While the United States is not the sole cause for the migration from these countries, the authors say it has played either a dominant or contributing role in these conflicts.

This makes the scary-headline conclusion pretty worthless.
Indeed and that's what Plan9 enables you to do
How popular is it in the Python space? I loved the large text widget and would love to contribute with a font using the Teletext 2x3 mosaics that got into Unicode 13 (which are fully supported in VTE)
Flu vaccines are effective — but the government has to try to predict which specific strains of flu will be active that season. If they mispredict, you might get the flu despite having the vaccine since you got a different strain.

For COVID-19, there is a known set of strains that hopefully won't change. So a vaccine targeted towards that set should work, at least temporarily.

The following is just me speculating: from what I have heard, coronaviruses are called such because of distinctive proteins on the outside of the cell that are hard for the virus to change. If a vaccine elicited an immune response to target such a protein, then it should be effective for all the strains.
Personal websites?
Well if it's unopened it might be worth a fortune someday, so hang on to it!
Or sponsored political thinkers giving an opinion people would want to read. Not really concerned with that right now, just wanted to make something I’d want to use myself.
Oh man, this is all so many social issues in a pot that's boiling over.

First, as someone with kids, I appreciate everything my company is doing to help me manage workload and parenting. I've been impressed with my company. Not all are the same though. A friend, who is a child-less female who works with two other moms and a mom-to-be is constantly getting saddled with the work that her team members are dumping on her because of difficulties. She gets more work along the implication that because she doesn't have kids, she has plenty of free time. Is that equating to compensation? No. Does it make her feel like a second-class work citizen? How could it not.

Second, especially in the Bay Area, there's a growing divide of who can afford to have kids and those who cannot. We can all espouse the importance of children to maintain the human race and build a better world blah blah blah. But that's all going to shit both literally and figuratively. Nationwide, costs of child care are impossibly high. Cost of housing is impossibly high. Healthcare costs to have a child are impossibly high. Parental leave is near non-existent. Tech firms can solve for parental leave and healthcare, but they can't and don't solve for day care and housing. The people having kids where tech firms are located are, indeed, privileged--because they're making enough money to counter the other two needs.

Finally, I've had my own challenges over the past few months trying to gaze into the future as climate change and fires make the air outside today look like a scene from the Fallout franchise. The government is inept. Science is disregarded unless it makes someones internet load faster. A bunch of dumb shits decide they want to ride their motorcycles and infect 250,000 and cause $12b in damages, while at the same time huge portions of students who don't get food at home can't even get the school meals they deserve? Did I make a mistake having children? What is this shitshow of a world I've brought them into? I'll be honest, we're already a world fraught for resources and maybe we all need to think about the duty to the next generation is to not have kids.
Yes, that was made in comparison to conventional vaccines that either use inactivated viruses or viral proteins
I can't think of anyone who uses LinkedIn for anything other than finding jobs.
I don't see how this applies to the Democratic Party any more than the Republican Party.
> Log files. Append-only mode, enforced.

Anyone know of any file system which allow partial initial blocks? Ie a file can appear less than a full block long by adjusting its length, any where there's an offset into the first block where the file starts?

Then you could easily do size-constrained rolling logs by simply adjusting the starting point of the file.
I think most societies around the world didn't and don't provide parents with any additional time. It just so happened the that most people had children and elders/women could raise them while the men kept working. Not to say that women didn't work, but whatever they did allowed them to keep an eye on kids, or relatives/neighbors did.

Also, increasing the population is one of the most damaging things to the environment, so there's an argument that not having kids is paying it forward to future generations also.
Systemic problems require systemic solutions. One-off problems require one-off solutions.

Parenting in the pandemic is a systemic problem. And even in non-pandemic times, we have public schools, child services, parental leave, etc. The national guard and jury duty are likewise systemic problems; we need lots of guardsmen and lots of jurors.

Homelessness is a systemic problem, but the particular way you choose to do community service (or not do it) is for you to sort out mostly on your own.
But ISIS was direct result of war on terror.
Also see Downs–Thomson paradox (https://en.wikipedia.org/wiki/Downs%E2%80%93Thomson_paradox) - improvements in a road network will not reduce traffic congestion, but rather can make it worse.
Why is that mind-boggling? We spend a lot of money and employ a lot of people to prevent domestic terrorists from doing such things.
Public health lessons learned from bias in coronavirus mortality overestimation
Well. As of now the Russian vaccine doesn't look like a trustworthy solution. Recently Russians published article in The lancet [1], but scientists who read this have a lot of questions. Especially on data consistency. They even published open letter to head of vaccine research Denis Logunov with open questions [2].

According to first reaction by Denis Logunov (don't have a link on this) the open letter doesn't worth to answer. Unless The lancet asks to react.

imho: It actually shouldn't be a surprise that if the government is corrupted, the other governmental institutions most likely do not function well either. This research center is a governmental institution. And might be interested and involved in some political games as well.

[1]: https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

[2]: https://cattiviscienziati.com/2020/09/07/note-of-concern/

upd: formatting
Epic still allows Fortnite to be sideloaded.

More importantly, Google does not prohibit sideloading. It simply does not make it convenient to do it.
Actually it will kill/impact aquatic life up to 150 miles downstream. That brine you talk of is not just sodium chloride, but many types of salts, acids, and other contaminants or processing agents. The reason they aren't Superfund sites is because they exist in less developed nations that dont have the same laws.

It's probably a step in the right direction, but I'm looking forward to supercapacitors or alternative battery tech.
Is this similar to outline?
I'm seeing $156k for L4 base or $266k TC. It'd be easier if OP just told us the actual figure, but either way the point stands, they're making multiples of the median household income of their area, with just one earner. And the calculus gets worse because a lot of the dual-earner households are likely having to incur childcare costs that they aren't.
>When a policy hits close to home: more work, higher taxes, reduced disposable income, suddenly support isn’t quite so robust.

Yes, because I'm not going to put my family at a disadvantage versus others in society unless everyone is going to chip in. That's a perfectly reasonable position to hold.
YES.

This is the replacement open-source GUI USB imager app I have been waiting for.

> 500KB vs 210 MB

Essentially this is a 99.99999% reduction of disk space and run-time usage with the same functionality which really puts its electron garbage counterpart to infinite shame. There is no contest here.

Feel the satisfying moment of removing this 'balenaEtcher' bloatware and replace it with a true, efficient and magnificent cross-platform native alternative app.
You’ll find that’s the case for several of the front runners.
What's amazing, at least here in Michigan, is that kids here are having the same problems. In Detroit according to figures I've seen two thirds of the kids lack Internet access at home.

They've got it easier than the Indonesian kids, they all go to McDonald's. Course to stay at McDonald's you've got to constantly be buying food all day or they kick you out.

Spoke with a Lansing developer and he said the schools are sending out cell hot spots home with the kids. One of the problems they've run into is some kids spend half their time with their Dad. So Dad wants a hot spot too ;<)! They school won't fund two so Mom loses access when they're at Dad's ;<).
Such terms are never offered to consumers only businesses as far as I can tell

It happens, but not as often as it used to. For example, in luxury retailing, if you're well-known by the store staff and have a long history with it, it happens. But it's always in the midst of a very high-touch situation.

It also happens with deliveries. Like if you have a regular wine delivery or something like that, and you're an unusually valuable customer, a business will happily send you a bill rather than keep a card on file.
If you don’t want to deal with this possibility then simply don’t have kids.

This attitude -- which is pretty common in the US -- never fails to astound me.

First, a lot of babies are not planned. Birth control failures happen or young people learn the hard way the facts of life because they fooled around ended up pregnant before they had a good idea of how things worked and some people are essentially brainwashed from birth into believing that using birth control will send them straight to hell. And sometimes people think "I will take my chances just this one time" and that one time turns out to be enough to result in pregnancy.

That's without getting into the reality that a woman can end up pregnant as a consequence of rape.

Second, if all people successfully take this advice and simply don't have kids, then there is no one to take care of us in our old age as our species dies out, having promoted the idea "You only live once and you should live for today and just indulge selfishly."

Children are the social capital of the future. They are future workers and future tax payers and future caregivers that people who are currently hail and hardy will someday need -- unless you want to follow up this policy with "Let's just start executing people who fall ill with anything that could require long term convalescence and, also, start executing people when they hit a certain age so we don't have to deal with the frailty of old age."

(No, I am not being extremist. I'm really not.)
Where Did Mafishi Come From?The True Story of CBU Good Luck Fish
Deaths are not the only metric. We still don't know the potential long-term side effects of COVID, even for "low-risk" people.

https://www.theatlantic.com/health/archive/2020/08/long-haul...
For Duo, Samsung UI was probably the culprit, which is unfortunate.