skysight-inc/HackerNews huggingface dataset:
"Exercise may be affecting telomerase activity and not telomeres directly."

Maybe exercise is affecting HGH and this is affecting telomerase. Do glands secrete telomerase? I'm not sure, but the pituitary gland secretes HGH and that could systemically affect telomerase. If so, then it stands to reason that rapidly decreasing HGH in somatopause in one's early 30's is the cause of aging because HGH is not as readily available to prop up telomeres with telomerase anymore, unless you're exercising... but:

I was under the impression that many runners look haggard, and this was due to decreased levels of COQ10 and more oxidative stress. Perhaps increased physical activity can go both ways too. I've also read about runners having scarring on the heart.

My approach to exercising and diet is simple. Eat healthy, continue learning about food and health (I started many years ago) and with any excess energy, go do some exercise but only to one's limit, maybe slightly over, if that. Keep eating moderately, and exercise again when it feels right. Listen to your body and respond to it with a palette of acquired responses (through learning and experimentation.)
Upgrading my HP 2910al to a 10GbE Fiber Optic Internet Connection
Showcase of Responsive Web Designs
App Engine already does.
This was great. I just wished that more in-depth articles like this one would rise to the top just as much.

http://news.ycombinator.com/item?id=2429082

ML may have lost the war, but from an academic and educational standpoint, folks in the ML community still have a lot to bring to the table.
pew pew!

If I take that picture in the article as the real thing, how in 7 hells do they keep the optics clean enough on a ship to fire the thing? Or do they need to; does ocean spray on the external-most lens not matter, maybe?
Back when I studied astrophysics at uni, I also found that the sheer scale of events like supernovaes, black holes, and other similar things, was just mind-boggling and fascinating. So I can totally relate to the author's excitement!

What happens when stars go "boom" in some way is just insanely huge compared to anything we're familiar with.
SONY ERICSSON SATIO REVIEWS AND SPECIFICATIONS
Yes, the stock market is automated-- and highly regulated.

Of course, the stock market is limited to publicly traded stocks, and there are all kinds of regulations applying to the actions of the companies traded.

If you are really interested in this area, you might want to start here:

http://en.wikipedia.org/wiki/Securities_regulation_in_the_Un...
http://news.ycombinator.com/item?id=1791749

http://news.ycombinator.com/item?id=1800876

http://news.ycombinator.com/item?id=1802072 <- 2 comments

http://news.ycombinator.com/item?id=1805419 <- 13 comments

http://news.ycombinator.com/item?id=1858254

http://news.ycombinator.com/item?id=1882297

http://news.ycombinator.com/item?id=1886532

http://news.ycombinator.com/item?id=2025766

http://news.ycombinator.com/item?id=2033198
Off topic: Since I will move to Luanda/Angola in a few weeks, I would be happy to find some hackers from that area. Please contact me. You will find my mail address in my profile.
Nah, they're far too young to understand it.
The key part:

As it happens, the disk that formed around the black hole was face-on to us, so one of those beams was essentially aimed directly at us.

Anyone know just how focused these beams are?
An odd additional factor is that philosophy departments are actually quite cheap, and at many schools turn a profit (see e.g. http://www.today.ucla.edu/portal/ut/PRN-bottom-line-shows-hu...). Their faculty earn relatively low salaries, grad students are paid little to nothing, and there is no equipment to purchase or maintain. They're so dramatically cheaper than some other fields that the total expense is often actually less than the tuition charged for the credit-hours they teach.
This certainly can't bode well for the planets that sun supported.
The app sounds interesting, and the website is polished-- but I don't think that you are going to be getting a lot of sales via the website. That's not how "Enterprisey" software, even at a low price point of $1499, is usually sold.

I think you're going to have to give some thought to your customer acquisition process (which is going to be different than the usual B2C or B2B methods you read about most often on HN.)
You are not alone in your fear.

This question of knowing your fate was well presented in Heinlen's short story Life-line: http://en.wikipedia.org/wiki/Life-Line

While I like the idea and being trailblazers must be done by someone you have to keep in mind that 23andMe only do genotyping not full sequencing.

In my mind the difference between genotyping and full sequencing is between building a partial array from bunch of if statements and actually copying the array.
Reports of ML's demise are somewhat premature. Now we call it F#...
They test a few different schemes, but it is sort of embarrassing that in their final summary graph (figure 9), they use the arrowheads again to indicate which representation performs best.
I have a graph theory based application in the Android market, "Edgy," and I doubt that I would switch to this. I think once you get used to it, it is perhaps clearer, but I think there are many opportunities for styling and weights that may increase clarity without having to do something that is not expected. If this catches on, of course I'll probably go that way, but as for now, I haven't even seen many, if any, graphs use this.
How does the 'drag bookmarklet to tab' thing work in Chrome? Where's the bookmarklet installed? (not among the bookmarks it seems) How can it be uninstalled?
TweetLand is a web & mobile game influenced in real time by Twitter
Cisco competitor to John Chambers: You're Too Big
Heh. When was the last time Dave McClure followed the Oakland A's? I mean, to take his analogy of "Moneyball" to his investment strategy to it's (il)logical conclusion, you'll have a bunch of start-ups that will make it the playoffs (seed) but never win the important game (series A).

Oh and other 'teams' will read the book, understand the new metrics that help predict success, spend more money, and win the World Series (e.g. Liquidity event). Maybe even do it twice in 3 years =)
Hi,

it is difficult to give good advices without some data. As first thing, I would suggest to honestly ask your "customers" what would they pay for.

Maybe you can propose some new features and bug fixes only when you reach a certain ammount of donations (I mean, this is kind of the way the Diaspora guys made their money).
If your target is developers, then to ask them money you may want to tell them how much time would they save with your new module or version. If a developer understands your new module would save him 3 hours of work, why shouldn't he pay for, let's say, as much as 1 hr of work is worth for him?

Finally, from my point of view, developers are easily the most price sensitive. So, another point would be: would it be possible to find another audience? Let's say small companies who may enjoy having their own job board?
One aspect to make sure to take into account is that it has to count down at less than real-time speed, since conditional-with-age life expectancy increases as you age (e.g. if your life expectancy at age 60 is 12 years, your life expectancy at age 71 is not 1 year).
Fantastic tool. I salute you and want to yell at you at the same time for making me stay here longer then I do already(haha). Great work friend.
I use a mnemonic algorithm to generate site specfic passwords instead, but this is _really_ nice. Do you happen to have the source on github, or would you mind putting it up there?
I believe it just executes the javascript on that tab. Navigate away from the page to 'uninstall' it.

Great extension!
Drag it to your bookmark bar (make sure it's visible first).

Then click it when you're on HN.
Open site explorer is not a time machine. It's a snapshot of links TODAY. Your assertion is flatly false.
A trivia game where using Google is allowed
What if I just add a place for visitors to donate and in return for donations I offer an arbitrarily small percentage of the company that just so happens to be proportional to the donation amount? Those who donate will just have to take my word for it. :P
>Education debt WILL be made dischargeable in bankruptcy again, there is simply too much pressure.

I'm not sure if that's possible - isn't essentially every graduate bankrupt? Couldn't every student get rid of their debts then?
Digital Legacies
Pure Ruby colored blob detection
Texas considers highest speed limit in nation
In theory it could have been someone else who sent in your sample.
He just knew the instruction codings and what not to use - e.g., "sub al, al" instead of "mov al, 0". He knew all of those by heart. Both in hex and in decimal.

(Me, I was able to read machine code from hex, but not write it unless it was extremely simple; and the hex<->dec conversion took too long. So I just used debug for those 10-20 instruction things)
I wonder if there'll be any effect from the fact that ML is now going to be the language used in CMU's intro CS course. They produce quite a few CS students, so there will be a cohort with at least basic familiarity with ML.
OOP = FP?
> ... I've moved back to Firefox 4 ...

That would be great, except FF4 doesn't let me log in to HN.
You mean like how stack overflow was having problems with Google not crawling their site, until they took a few minutes to set their site up to be Google bot friendly?

http://www.codinghorror.com/blog/2008/10/the-importance-of-s...
As much as SPDY is interesting there are a number of problems that are keeping it from being adopted:

1) Only Chrome supports it and even there it isn't fully supported. One really painful thing it is missing is support for switching from normal HTTP to SPDY without using NPN.

2) It requires the TLS NPN extension to function seamlessly. This is something that is just now being put into the OpenSSL package. It is why you need Chrome to do anything with SPDY, it has a special patch it applies to its internal version of OpenSSL.

It is good that people are taking interest but there is still a lot of work to do.

After seeing http://www.igvita.com/2011/04/07/life-beyond-http-11-googles... I decided to fiddle with doing the same with Node.js https://gist.github.com/911761 I'll be shoring it up into a real module but it is going to require changes to the zlib compression module, the bufferlist/binary module, the put module and to be really useful it will require a special build of Node.js and OpenSSL.
So this is a thin client that interfaces with processes that run on the server? meaning the state of the image and what has been done with it has to be kept in sync between the client and the server - this isn't pure client 'html5' using canvas et al

What language/env is the server-side portion of this?
Thanks for noting which ones include comments! :)
They appear to be on the east of the device ("iPad" button being south)
Would my simple aluminum foil hat be enough to ... uh ... foil a laser gun?
> However, it isn't unreasonable to see a situation in
> which follower counts on sites like Github, Dribbble,
> Quora, etc. do become scalable ways of signaling. They
> aren't perfect indicators of ability or knowledge but
> then again, neither are college degrees

"Karma"-based mechanisms favor a very specific personality profile. One that doesn't necessarily correlate with aptitude.

Just have a look at the SO superstars -- none of them are auto-hires for all situations. You'd need to evaluate them individually and carefully. Presumably to a degree that makes their community rating superfluous.
That makes sense, seeing as most philosophy isn't that useful.

Let the students read some Socratese, some Stoic, some John Locke and some Aristolean writings - that should enlighten them enough.
Some sort of water-repellent glass? Or maybe simply a plain old lid. It would be possible to keep the lens closed for most of the time, except for the short period when it is actually active.
They appear to have skipped curved arrows, which would reduce the muntedness of the graph considerably. Do please correct me if I skimmed poorly.
So why do we need this vs just shooting things with bullets?

I'm down with the crazy railgun systems they've developed, but this seems like a boondoggle.
Interestingly, I would argue that we've got two oppositional forces at play in today's admissions game:

1) Seldom before in recent American history has it been easier for a well-qualified, but SES-disadvantaged student to gain admission to Harvard.

2) Seldom before in recent American history has it been harder for an SES-disadvantated student to become well-qualified to gain admission to Harvard.

Once you've reached the admissions gates, so to speak, your merit is a better calling card today than it ever has been. But getting there is becoming tougher and tougher, thanks to a chronically deteriorating public education system and increasingly costly college-preparatory mechanisms.

It is commonly assumed that the rich receive advantages at the gate. Rather, they've been receiving advantages throughout their lives that increase their likelihood of getting to the gate in the first place. It's a subtle, but important distinction.
A Google a Day: trivia game where using Google is allowed
True. You could always adjust it and it would still serve it's main purpose.
Go to a top-league university and an English degree is bloody difficult.
I see what you're saying, but the process he describes does work. Don't focus on the word 'cores', just think clients.

E.g. 'If you have a 10GB text file, it can be faster to split the file across multiple connections when pushing it to S3.' That sounds OK, yeah?
Ask HN: A Taxonomy of Startup Strategies
I've been observing online startups for a few years now and I'm interested in identifying a taxonomy.

I just put these together. Note that these are intentionally kept vertical-agnostic.

High-scope Infrastructure - use domain knowledge and innovation to provide a turnkey solution to a broad array of customers. Customers outsource to the service instead of attempting to roll their own equivalent. The company gives them a better solution than they could build for the same price. These startups usually ride on a new innovation and are capital intensive. (Amazon EC2, AppJet, Skype, Heroku, Sendgrid, Dropbox, iPad PoS)

High-scope Web App - as above but the utility is delivered via a traditional web app. These companies are still 'high-scope' even if they only provide services to a particular vertical, because their solution is usually more general than an equivalent in-house one would be. (Basecamp, Hoodle, Freshbooks, Convore, Wufoo, Xero, most SaaS)

Direct Marketplace - facilitates real commerce directly between two parties, where one or both can be a consumer or business. Users are attracted to these services because they can trade goods or services. Reliance on network effect. (eBay, Etsy, AirBnB, limos.com, Smarkets, Groupon, Kickstarter, 99designs, Theme Forest, GumTree)

Ad Marketplace - as above but for ads only (Gumtree, Craig's List)

Ads with peripheral service/content - visitors are attracted by the utility of a service or by engaging content, revenue from on-page ads. Even though the 'peripheral service' takes significant effort, the underlying aim is to drive traffic for the consumption of ads (Facebook, Google, SongKick, about.com, justin.tv, Reddit and other community sites)

Do you agree with these? What would yours be?
For a minute I thought this was an April Fools joke, but it looks like an awesome idea. Wonder in what other ways this would be do-able. Antlers I imagine would need much higher resolution images from a fixed vantage point to detect similarity...
> But what if Harvard had enough capacity to admit everyone who met its admissions standards?

What if the admission criteria is top n candidates? (not top n % of the candidates, mind you), which is very likely (and valid criteria for Top Schools, with legacy/brand to defend, limited/finite resources/talent pool, which would not scale lineary, IMO)
>"Why aren't there 100 Harvard franchises?"

Demand and supply. If you flood the market with Harvard graduates their perceived value goes down. The same reason why limited editions exist.
"Haskell is the world's leading purely functional programming language"

Why do people have to write stuff like this? What is "leading" and why would that be important?

And, BTW, I am quite sure there is a lot more Erlang code running on phone centrals around the planet than Haskell code.
Wow, this is great. Love the animated Y, too.

Two suggestions, maybe to add as options:

- open both comments and articles in new tabs automatically, since the assumption is power users keep the home page open anyway.

- Display the new comment and vote count as a difference? Seems more intuitive to me.
Movers and the Different Types - Pros & Cons of Hiring Movers vs Self Moving 
Moving guide: comparing the pros and cons of moving yourself versus hiring professional movers.
Erlang is not purely functional.
IIRC it depends on the black hole. Right now there isn't a precise formula for it.

The breakup of the star would form an accretion disc, the jets would form at the axis of rotation. The formation of the jets are classically mechanical (conservation of angular momentum by various means) and so the focus of the jet depends on the speed of the matter being ejected, the amount of matter being ejected and the mass of the black hole.

Moreover, the matter falling into the black hole is heated to plasma level and so there is very strong magnetic activity. As the accretion disc spins, the magnetic field lines twist along the axis of rotation - the same axis as the ejected matter. This has the upshot of focusing the jets very tightly.

http://en.wikipedia.org/wiki/Black_hole#Accretion_of_matter
Encoding-related XSS problems
Unfortunately bullets take time to arrive at their target and are effected by gravity. That makes lasers better for shooting small things far away traveling at high speeds.
Don’t Forget About Image Search
Is Podcast Marketing Worth the Effort?
REST and Stateless Session IDs
Sure you can.
openssl s_client -connect google.com:443

Not sure what the equivalent is on windows though.
The benefit is real end to end connectivity without the need for co-operation of everyone along the chain (this is an extremely serious issue, often even one layer of NAT makes trying to get port forwarding a nightmare, imagine 2 or 3) . Its also much more scalable than both. In the long run supporting some kind of gargantuan NAT/SOCKS translation layer for millions of customers is going to be much more expensive than ipv6 support, because IP is fundamentally stateless and designed to scale massively, NAT and SOCKS are not. This becomes a serious concern at larger scales.
I've written a "json" command line tool with nodejs that offers transformation of JSON with modern javascript expressions (with support for Array.map, Array.reduce etc).

http://fforw.de/post/scripting-json/
I think turning this into a userscript will play into the whole 'keep HN open all the time' better since you can just open HN, pin the tab and let the userscript work its charm.
Is Peter Thiel qualified to opine on Education? (This is not a snark, but I am genuinely curious to know how to process his opinion.)
Most reflective surfaces are only around 90% reflective at most and cease to be reflective after absorbing a fraction the energy a laser is putting out. You can make much more efficient mirrors, but usually only for a specific frequency.
Want to package this up into a Chrome extension (maybe as a userscript)? Then people could run it without clicking on a bookmarklet.
Press Ctrl-Shift-B to show to bookmarks bar first.
First Three Adobe Photoshop Touch Apps for iPad
We could also say it's the leading FP language that starts with "H"...
Bootstrapped Budget? 3 Inexpensive SEM Areas To Focus With Empty Pockets
"Proverbial Stanford" coincides a great deal with "Proverbial Harvard" - both are wealthy private schools that admit the very best students and have society's bias towards the well-to-do sons of well-to-do fathers. If you're looking for a school to contrast with Harvard, Stanford is a poor choice.

Furthermore, actual Stanford isn't doing any damage to actual Harvard. The data I've found suggest that 70+ or 80+% of undergrads admitted to both Harvard and Stanford pick Harvard.

Sources:
http://college.mychances.net/college/tools/college-cross-adm...

http://mathacle.blogspot.com/2008/06/harvard-yale-princeton-...
How is it a dead horse? Many ISPs are working on implementing IPv6. Some ISPs here in the Netherland have been offering it for quite a long time. Large sites (Google, Facebook, etc) are also slowly adapting it.

Yes, the transition is going very very slowly. But I don't think there is a problem. One could argue it's the same with IPv4 addresses as with oil. Eventually, it will get more expensive as it gets more scarce, and people will gradually switch to alternatives.

At a certain moment all the important sites will have adapted IPv6 that it's economical for some users to drop expensive IPv4. Sites will then hurry to go to IPv6 as they lose customers. But I guess there's no need to hurry yet... at least for us IPv4-rich western countries.
I guess accuracy is the main benefit. You can aim a laser a lot more accurately than fast-moving chunks of metal...

Also, lasers are cool. I'm sure that's a factor :-)
> Fiber optic transceivers are crazy expensive--easily equally or more pricy than CPUs by both size and weight. I'm glad we don't need a long run!

Presuming you are connecting devices within the same rack, you can easily get a 10gbe card and relevant twinax cable for less than 500 bucks -- these cables have dedicated SFP+ modules on each end, eliminating the need for transceivers.

The switches, on the other hand, will cost you a pretty penny
The Unix Hater's Handbook attributes that quote to Admiral Grace Murray Hopper, but without citing the source.

Wikiquote cites others as having said it, including Andrew Tanenbaum, Patricia Seybold, and Ken Olsen.

http://en.wikiquote.org/wiki/Grace_Hopper
for those interested in just the code, gist here https://gist.github.com/913400
I'm pretty sure Sony's goal there was to gather information to support their argument that a California court is the right venue and generally to intimidate geohot. Not to sue anyone who merely viewed the page.
Regarding the IP address privacy stuff...this can already be a problem with IPv4. At home, Comcast gives me IPv4 DHCP leases that get renewed to the same address for many months at a time. At work I (and most other employees) have a static IPv4 address. There is no way with IPv4 to do something like RFC3041 IPv6 random host addressing.
How WikiJob increased sales by 34% by A/B testing customer testimonials
Such a system would actually work out to be more exclusionary if the size of the application pool increases year over year (which, in praxis, it has been). At least a percentage-based system scales up with the size of the application group. A fixed class size does not.

For what it's worth, as well, I'm pretty sure that your system is the one actually being used. I would imagine -- but do not know for certain -- that schools like Harvard try to keep class sizes relatively fixed. It's not that their policy is to admit n% of all applicants, but rather, that their policy is to admit n students, and the size of the pool feeding into n keeps going up. Indices, rankings, and people commonly report only the percentage. But the percentage is an output of the system and not an input.
Most of the items in your second list have a (potentially) very strong SEO component. For example, optimizing content for users involves making changes to the content that is the very basis of SEO marketing.
I play around with Haskell quite a bit, but not so much ML. Do you know why ML won out at CMU?

I'm reading Cousineau's "The Functional Approach to Programming", which is based on ML, and I end up just translating most things into Haskell--the syntax feels much cleaner to me.