skysight-inc/HackerNews huggingface dataset:
A hacker can swap my name + address with a murderer right now without access to my DNA.

All of the hypotheticals in this thread (except for the CRISPR future superweapon) can happen right now without the need of a DNA leak: the US had an explicit system of racial discrimination encodes in the law until the mid 1960s without the need of 23AndMe. My insurer already has data about my genetic diseases and pre-conditions from blood tests I did as a baby.

I want to be worried about the leak, but I really cannot think of any consequence that's not a crazy sci-fi hypothetical or something that can be done more easily without access to the DNA database.
There's also the Dark Forest theory which suggests any space faring civilization which broadcasts signals too loudly is "quickly" eliminated/threatened by a more advanced civilization. All that remain are the civilizations smart enough to remain silent.
Especially given that the media has been pushing a narrative that the worst-case scenarioes are our actual reality (or even worse-than-worst-case ones), so ruling them out is in fact incredibly significant - it's effectively ruling out what readers of articles like this one are likely to expect to actually happen. (To be fair, it looks like Bloomberg are slightly better than some of the rest of the press in that they seem to have rejected stuff like RCP8.5 that has already been falsified by what's actually happened, rather than pretending it matches reality.)
Techtic Solutions Inc. Listed on Clutch 1000:List of Top B2B Service Providers
As a layman, I don't understand why future investment isn't priced in already?
No, but for having the results stored at some company.
This would be also great secure OS for chipset microcontraller (like Intel ME running Minix OS).
Happy to add any demos / papers to this post that you think are worth linking.
But also: https://ridiculousfish.com/blog/posts/old-age-and-treachery....
1Password, https://1password.com (Personal, Family)

I'd definitely introduce and use Bitwarden for teams.
Pass: https://www.passwordstore.org/
> is a restaurant that is the only British food outlet on Main Street, Springfield a monopoly over the British restaurant industry on Main Street?

Which brings you to the question of substitution. If the only British food outlet on Main Street, Springfield raises prices by just a modest amount, does that cause a significant number of customers to take their business elsewhere? If so, they haven't got a monopoly and the "elsewhere" is part of the same market, which in that case would presumably include restaurants serving different types of food or which are still in the same general vicinity.

So what's the substitute for the App Store? If they raised prices, could developers switch to Google Play instead? Well, no. Developers need both at once because they each reach different customers. If Apple charged too much a developer might abandon the iOS market entirely and use only Google Play instead of using both, but none of that business from the App Store could get moved to Google Play because those customers don't have Android devices and Google Play doesn't distribute iOS apps. They would just have to lose all of that business, not substitute Google Play for the App Store by moving the customers over there.

Compare this to where you stop selling your boxed software to Amazon but continue selling it to Walmart and Best Buy. Most of the people who would have bought your software on Amazon still want it, so they just buy it from some other place. The same customers. Your iOS customers can't do that because nobody else distributes apps for their devices.

Also notice that they did this on purpose. Suppose the owner of the only "British food outlet on Main Street, Springfield" is also a landlord who owns 20% of the land in the city. They don't have a monopoly on land, but then what they do is build a wall around the portion of the city they own, so that it's a two hour drive around the wall to get out of their domain. Then the competing restaurants that had been "one street over" are on the other side of the wall, which puts them in a different market (can't substitute them anymore), so now they've got a restaurant monopoly.
Why good commit messages matter.

https://chris.beams.io/posts/git-commit/#intro
How well does that really work out? It seems like that would aggregate a lot of cruft, or are there ways around that?
One of the most important lessons I learned early on as an entrepreneur is the concept of well-qualified advice.

When you're green, it's natural to seek advice from people you trust, people you think are smart, people with a lot of life and or business experience, family members, and so on. In most cases their advice is either going to be too general to be useful or they're going to have no knowledge and experience at what you're specifically working on, your domain, so their advice is far more likely to be dangerous.

Those people will want to help, people like to be asked for advice, it feels nice; I think most people like to hear themselves talk, it's a normal thing. Their intentions will be good. I also think it's common for people to not have a good grasp of where their expertise ends and where their weakly-supported opinions begin (something everyone is guilty of at times). If you ask for an opinion, input, advice, you're likely to get it, even if the person isn't very qualified to offer it. So it's important to be very selective about who you seek advice from, making sure that they're in a position to offer valuable insight to what exactly you are dealing with.
if they construe their DNA data as not health information, but instead information like finger prints?
both lack the left+right click that reveals tiles around numbers that have the sufficient amount of bomb marked, I'm curious what's the css/html limitation that prevents the implementation of that behavior?
And all of that is actually bad because it is so ridiculously far from the home row that you have to move your wrist to reach it.

What can you actually do faster on the numpad if the starting position is your right index finger resting on J?

Because that's where it should always be.
That seems to agree with what a friend of mine who worked there, and how he was rewarded (or not).

I can't help but think they are rewarding the right thing -- new shiny things may have the best ability to bring stragglers onto google the platform.

Unfortunately, it leads to the feeling that google just dabbles in things.
If a child has 2 copies of a variant you know both parents have at least 1 copy.

You know what parent a male's X and Y came from.

You can use phasing and linkage to reconstruct parental haplotypes.
Nvidia will build 700-petaflop supercomputer for University of Florida
Your data, your rules.
I put my 23andme raw data in github (https://github.com/sbassi/MiGenomaSbassi) for the world to see and use without asking anybody in my family.
MineSweeper implemented in CSS and HTML and no JavaScript
I am a model and I know that artificial intelligence will take my job
What is perplexing about it? Genuine curiosity - where I live those views would probably be considered mundane mainstream.
Old multi-port serial consoles can often be found used quite cheap.

Personally, I'm a big fan of the OpenGear units. They're *much^ more than just basic serial consoles and are quite extendable. You can even write your own scripts to interact with them, trigger them on specific events, and so on.
Please provide more details, insights, anecdotes, and examples of why you think S-expressions are superior.
The GNU people are absolutely obsessed with correctness and performance. It's kind of annoying actually. I assume it has something to do with RMS' ties to MIT and Lisp machines (an example of staggering complexity), see Richard Gabriel's "Worse is Better" essay.

I tend to fall in the NJ school myself, though I do think Emacs is something special. And though it's derided as slow, Emacs has a ton of super crazy optimizations, especially around rendering.

Pretty much every GNU project written in C is totally unreadable and hopelessly baroque: gcc, glibc, coreutils, etc. For fun, compare some OpenBSD Unix utility implementations with their GNU counterparts. The OpenBSD tools' source code is a joy to read and represents the pinnacle of elegant C. The GNU versions are ugly as sin, but functionally superior in pretty much every way. I don't really agree with how they write code, but you got to respect the almost OCD attention to detail: no edge case goes unhandled.

World's apart from the terse and cavalier style of traditional Unix hackers.
But military requirements seem to have played a significant role in how the Shuttles became what they were. A purely civilian space race wouldn't have had shuttles at all, or at least a very different design.
This is only true of getting the investment is your terminal goal. If it’s just a proximate goal on the way to actually building a successful company, getting stinking rich or many other things that’s not true. If the investment is an end you’re right. If it’s a means to an end...
Korean is special because it still has the one remaining unicode bug in the spec, U+ffa0 HALFWIDTH HANGUL FILLER is still a valid identifier. http://perl11.org/blog/unicode-identifiers.html

Almost nobody got that right.
The more competition there is in this space, the better, and this looks like a very nicely polished solution right from, the get-go. I would definitely give this a go for smaller projects, as an alternative to MaterialUI or ant.
The Brave New World of Chemical Romance
I find there are two motivations here.

First: "I am seeking to understand", and

Second: "I am seeking to cause disruption - perhaps just because my opinion was not centred in the original decision-making process"

These can look similar, because the second will disguise itself as the first.

Good leadership should permit as much of the first as possible, and stamp out the second.

The tips in the article, which are great, make it much easier to quickly distinguish between these two cases.
> basic housing

What about a YC building complex a bit outside SF? Maybe one close to NY too, and ... two in Europe, two in ... each continent? :- )

"Ycplex"? "Hackerplex"?

There could be a gym so people could stay healthy (and what about child care & school?).
Then do it! Contact the Autoriteit Persoonsgegevens [1], that's exactly the point of my comment.

[1]: https://autoriteitpersoonsgegevens.nl/en/contact-dutch-dpa/c...
Show HN: Learn Evolutionary Algorithms with Python Notebooks
I've gone back and forth on this. As a kid I read plenty of older SF where humanocentric biases were laughably prevalent. Aliens were amazed at our incredibly advanced mathematics because we used the clearly superior Base 10. Or aliens adopted English because it was so much more sophisticated than their own languages. Aliens all being basically humanoid was explained because it is clearly the only body form suitable for developing advanced technology.

In a kind of allergic reaction to this sort of thing, there was a movement in SF that aliens would be likely to be so different from us that we would be unlikely to even recognise them as intelligent. Stanislaw Lem's Solaris is a well known example, and the Pandora sequence by Frank Herbert was interesting. I never quite bought it though, and Nemesis by Isaac Asimov seemed to me to be a particularly lazy example that pretty much put me off the whole idea. (I'm a fan of Asimov, but this one didn't work for me).

On the one had we can look at life on earth to see the huge variety of biological forms that are possible even just on our own planet, with fundamentally the same core biology throughout. On the other hand, any life in our universe is going to be constrained by the same basic principles of chemistry, physics and emergent constraints such as thermodynamics, information theory and natural selection. The problem with most of the efforts at 'truly alien' aliens is they emphasise their alien-ness by showing them violate such principles to show how 'we don't know as much as we think we do'.

I don't buy it. Thermodynamics, natural selection, information theory, etc - we know these things. They're real constraints that any life, anywhere must contend with and they constrain what can or can't work within comprehensible limits. I'm not at all saying that genuine alien life can't be surprising, that we won't learn anything new from it. We learn new stuff form like here on earth all the time. I'm just saying we actually know a pretty decent amount about how the universe works at a basic level and this will give us a decent chance at figuring this stuff out.

That's where I am this this now, but it's a complex issue. I really need to watch Arrival though.
> you are just the type of person who will defend roman numerals.

In the face of what? No system for writing numbers? Sure. Arabic numerals? No way, they're far superior to Roman ones.

> Almost the entirety of calculus was derived from problems related to physics.

No it is not. It is/was largely motivated by problems in physics. One may obtain a lot of intuition about calculus from physical intuition, but one does not obtain calculus from it.

> Volumes were calculated for doing engineering.

Yes. And?

> Mathematics != Thinking.

I don't see anyone in this thread claiming that.

> The last time I checked both logic and critical thinking were branches of philosophy.

I thought we were talking about math?

> All good mathematicians are physicists or engineers.

This is patently not true. Tell me how many Abel prize winners of Fields medalists are physicists or engineers. There are indeed some, but they are a minority – your claim is absurd.

> Heck some even learnt maths on their own.

Absolutely. Can you elaborate on how this is relevant?

> All mediocre mathematicians write textbooks and hide behind notations.

What are you on about? As a mediocre mathematician myself, I must admit I have never written a textbook.

> Most abstract mathematics is like the definition of protocols/interfaces and other platonic garbage.

You have made it abundantly clear that you haven't that slightest grasp of abstract mathematics. Would you at least humor me as to provide a few examples?
Except that it would still be delivered as an opaque binary blob. The GP's suggestion isn't much different from Intel's proposal for abstracting drivers into EFI Runtime Services, and many people see those as a security risk (in a "you don't control your hardware" sense, not necessarily in a "it has bugs" sense).
Can we just embed Flutter in every browser? !important
The mRNA vaccine field isn't related to monoclonal antibody production.
My biggest grip with Gnuplot was that the default style is pretty terrible. For everyone looking to make graphs, two pieces of advice:

- Use pngcairo, or pdfcairo or something like that. Nobody likes graphs without anti-aliasing.

- Use a nice color palette, from https://github.com/Gnuplotting/gnuplot-palettes , such as dark2 or viridis.
The D compiler really is impressively fast. To the point where for most projects the compile time is dominated by the linker. It really makes you appreciate how nice a tight feedback loop is when programming.
Erfurt Latrine Disaster (1184)
With a lockdown you slow down the infection. This has a few goals at the same time.

First, you lessen the load of the healthcare system. If a lot of people get sick at the same time, hospitals would be swamped and more people would die because care is impossible.

Second, you can bring the disease from an exponential growth to sub-exponential, potentially containing it mostly (this is what happened for example in Germany, where tracking individual infections is now possible again).

Third, you buy yourself time until a vaccine is available. Even if no vaccine is going to appear in the near future, as long as you slow it down long enough (1-2 years) from reaching saturation in the population, that's lives saved.
Basecamp and Hey founder Jason Fried on fixing email
I just gave a few examples of why Windows is becoming better for non-iOS developers.
Application Logging Made Simple with Kubernetes and the EFK Stack
Both mRNA vaccines so far have produced T-cell responses with Pfizer/BioNTech producing more CD8 than Moderna. Both had detectable levels of responses, though. As is typical in clinical development, we need to wait for the phase 3 data before making a decision.
I think the common term is "intermittent fasting" (despite the protest about the word "fasting"), which covers a range of strategies—"time-restricted feeding" is the type where the fasting period is less than a day. https://en.wikipedia.org/wiki/Intermittent_fasting#Types

There is at least some research supporting the claim that time-restricted feeding inhibits the growth of cancer in humans: "In repeated-measures Cox proportional hazards regression models, fasting less than 13 hours per night (lower 2 tertiles of nightly fasting distribution) was associated with an increase in the risk of breast cancer recurrence compared with fasting 13 or more hours per night (hazard ratio, 1.36; 95% CI, 1.05-1.76)." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982776/

There have also been studies in mice: "Results and Conclusion: TRF had a dramatic effect, reducing tumor growth in obese mice fed a high fat diet (HFD) to levels seen in lean mice. Tumor growth and initiation was also delayed in the transgenic PyMT model of mammary tumorigenesis. Our results further suggest that the antitumor effect of TRF is at least partially mediated by reducing hyperinsulinemia, suggesting that this intervention may be effective in breast cancer prevention and therapy." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552025/
It seems to me that the value of advice is not to get people to change their behavior right now, but rather to plant a seed in their mind that will make it easier for them to grow in the future.

For example, before founding my startup, I read countless articles about the value of iterating fast. Yet I made the mistake! It seemed almost unavoidable.

However, because I had read that advice so many times and actually agreed with it, it made it way easier to correct course. As soon as I realized that I was making the mistake, I integrated all this previous advice very quickly.

Good advice does help, but it can only be integrated when one is ready for it.
How I Made My First App at Age 17 with Flutter
Where do I reset my DNA?
Another discussion, currently on the front page: https://news.ycombinator.com/item?id=23920987
Association of outdoor night light with mental disorders in US adolescents
> If anyone wants to write detailed, high-quality articles about automotive engineering on a similar basis, drop me an email.

Will you also match LWN by paying $300 and up for accepted articles?

Not sure why you were downvoted, but it might be a good idea to put up a page explaining your goals and perhaps do your own Show HN so more people can see your offer.
From what I understand from the latest news reports, the primary way to stop the spread is with masks. So if we can reopen but with masks, that may be effective enough.
> If you plan to migrate your customers to IPv6 then you are a lunatic.

According to https://www.google.com/intl/en/ipv6/statistics.html#tab=per-..., IPv6 adoption in the US is above 42%. Was that all done by lunatics?
found this on reddit for this post:

"I applaud this. And it reminds me of the up-goer five. https://xkcd.com/1133/"
Yeah - to be clear I was referencing another post with that quip. Like most advice, it’s got some merit, but reality is much more complicated. Kinda the point of these posts really!
Unfortunately, it appears this technology is made available only for research purposes¹)/people with an institutional email address.

Which means that the best way for DYI mocap that I know of is still getting hold of an increasingly rare Kinect One.

¹) https://gvv-assets.mpi-inf.mpg.de/xnect/?page_id=12
Most of them, were, IIRC, only "reported to" parliament. After reopening on May 4th, some of them were voted.

I admit I worded my post poorly: a state of emergency exists, but limiting constitutional rights is, AFAICS, only permitted through law.

"DPCM" are mere administrative acts, and a few people expert in the judicial system have raised objections about their use in this way (including the head of the constitutional court). In particular, the debate is whether they can or can't limit constitutional rights.
I wonder what Meat Loaf's range is (since it's not in the chart)
Yeah, we live in a culture where thinking about anything but next quarter revenue is discouraged in companies. In such a culture, anything but a status quo is not going to happen easily.

See also fossil fuels.
GPT can be used to build auto suggestion to search engine. scalable and intelligent crawling, indexing, serving, re-ranking parts are still needs to be developed. IMO, success of search engine business is not merely a technical advancements.
> The user joshuaissac gave a very good description of a 'field' as a response to my comment and it was about the same length as the definition on Wikipedia. It shows that it's possible.

Sure, his definition is also a good one. It leaves out a lot, though. Which is fine, if one can assume the reader knows the context. My definition, too, leaves out a lot (it assumes set theory), and rests on the informal language known as English.

> I don't see why certain knowledge should be out of reach of those who are not involved directly in that field.

It isn't. The content of mathematics research papers may well be out of reach, but that's quite natural, don't you think? I, as a mathematician, do not expect to be able to read research papers on chemistry without putting in a lot of work.

> I could explain complex software engineering concepts to a layman.

OK. It does not follow from that that everything can be explained to a layman. Some things are easier to explain with layman analogies and mental images than others. However, to keep this fair, I think you should see how many laymen can follow Wikipedia articles on complex software engineering topics with ease! That is, afterall, where we started this discussion.
Bitwarden. Works well and the integration with 2FA/TOTP is amazing. I highly recommend to not rely on a single (mobile) device for 2FA. Loosing or breaking it might shut you out of certain accounts forever.
It isn't over until the fat lady sings as they say. Anything can still happen with North Korea. Personally I imagine a revolution of some sort to be rather much more likely than North Korea somehow being the first eternally stable state in the world.
Death tolls require some time to go up.

If you lift lockdown, lots of people get infects. It takes a few days, maybe a week to show symptoms bad enough to go to a doctor for testing. This is the point in time when cases begin to go up. Imagine if you lifted the lockdown for a day and went back.

One to two weeks after that, people will get more seriously ill, requiring hospitalization. Initially this can be treated easy at a (presumably) low-load hospital with no issue, the death toll is low.

One more week and you have the majority of cases in the hospital, this is where most people will die. A month after you lifted the lockdown.

Now imagine not locking down after that one day. After 1 month, you're at the peak of Day 1 infections, the next day the peak of day 2 infections etc. It compounds fast and can overwhelm a hospital.

Once a hospital is unable to care for all patients properly, triage will be applied. People with good recovery chances will receive treatment, those who are risk groups will not.

That's when your death toll will explode very suddenly.
They embedded a JSON string within the JSON itself.

I wonder if it would’ve been better for them to Base64 encode their message. Of course, this itself presents other problems.