skysight-inc/HackerNews huggingface dataset:
MRI is ~5 orders of magnitude less precise than EM. Not even close to cellular resolution, let along single axon resolution. You can only see axon tracts, where thousands of axons may make up one pixel.
The book you might be referring to is "The True Believer" by Eric Hoffer. Published in 1951. It's about 175 pages. If you've ever wondered why political correctness, BLM and anti-racism resemble a religion (non-theistic) it is definitely worth a read.

*edit

I would have liked to remove the part about political correctness, BLM and anti-racism as it does nothing to contribute to the discussion and the question can be answered without a reference to any of those things. I will not, because to do so feels misleading.
I wonder why the "at Google" is necessary for the title. I'd be very surprised to see an organization not use some sort of design doc before building things - the only thing that would be different is the scale and scope of them.

Of course, you won't see a "Design Docs at Amazon" on the front page of HN for...some reason. Gee, I wonder why?
Nice! This is awesome!
Interesting, can this be merged in some way with the concept of signs in postmodernism a la Baudrillard? It would be an interesting marriage
It's far easier to live off of ramen when the worst that can happen is that you fall back on your savings, or your family (for a home), or your MBA network (for a job), etc, when your business bottoms out.

This means that it's naturally a filtering function for people who have such safety nets already. It means that there are people who would be putting their lives and the lives of their dependents at risk in order to make the YC gamble.

It might be a filter that "works," but it will inherently be an uneven filter, doing very little to filter founders who already have the means, while effectively barring many potential founders from being able to participate at all, at least not without dire personal consequences.
It's not a design system. It's documentation/best practices around common UI components that you'd find in most design systems.
Would love to know YC's real matriculation rate. I know of several teams that got accepted in and opted not to go, in part because of ballooning batch size and dilutive terms.
> Small sample size, but this is consistent with what I've observed in some specialized people... For example, I have an uncle that is absolutely brilliant. He's an excellent lawyer and can remember any fact that even slightly interests him. He's simultaneously the most absentminded person I've ever met - he forgets meetings, is always mindlessly snacking (despite being on a diet for pre-diabetes) and generally forgetting things that he doesn't deem to be important. It always feels like he traded something that "normal" humans have for his smarts. It might just be mild autism, but it seems to me like savant autism is an extreme example of this effect.

This seems consistent with how my mind works. It takes an extra tax of effort for me to remember things with "emotional" or sentimental components to them, but I'll be a walking encyclopedia of knowledge with the necessary critical thinking capabilities to apply what I know.

Would be interesting if brain scans yielded similar patterns between the two of us. Wouldn't be a surprise either.
But in an hour Google will return this thread as a result. Be The Change You Want To See.
I have plenty of history with global state, various contexts in large applications, that make testing code unnecessarily complex.

So, yes, global state is sometimes necessary, but it absolutely should be avoided, and access to it should be restricted.
So ... just serve your markdown repo using Caddy.

https://caddyserver.com/docs/markdown

”Caddy is both a flexible, efficient static file server and a powerful, scalable reverse proxy. Use it to serve your static site with compression, template evaluation, Markdown rendering, and more.”

https://caddyserver.com/

Here’s a blog on doing this with the older version of Caddy:

https://blog.thomaspuppe.de/static-sites-from-markdown-with-...
> For example, why do I believe that the NYT statement is dishonest but the Tucker statement is honest?

Because Tucker Carson says all sorts of racist dog-whistle stuff? And, I don’t know if Carlson apologizes or officially retracts statements when they’re proven false but I know The NY Times makes a consistent effort to do so. And, Carlson is a talking head and The NY Times is a newspaper that has one of the stronger reputations for fact checking?
Well, I hope you aren't right. But I have to admit you might be.

How do we figure it out? What data do you have? If none, or if it isn't statistically significant, where or how do we find it?
Cave discoveries suggest humans reached Americas much earlier than thought
If you want the best of both worlds, then try VictoriaMetrics. It is simple to deploy and operate and it is more resource-efficient comparing to InfluxDB. More on this, it supports data ingestion over Influx line protocol [1].

[1] https://victoriametrics.github.io/#how-to-send-data-from-inf...
Yes that is common across nearly All Japanese companies and that is why I have been critical of them in terms of global expansion. ( And especially in Tech )

But things are slowly changing though. Those that are younger generation ( Comparatively Speaking ) are in middle to higher management roles are more open and less hostile, so you start seeing a few Japanese companies picking up actual productivity increase and competing.
I'll also plug https://www.electionscience.org, an awesome and underfunded nonprofit that helped get Fargo's approval voting initiative passed. (I've donated to them but have no other affiliation.)
> I want to learn an new Programming language, and eventually build a project with it.

Which part is more important to you?

I want to learn an new Programming language => Rust
build a project with it => Go.

As a language Go is not very large or interesting, introducing a couple unique ways of doing things. This let's you pick it up quickly and get going. Rust is far more interesting a language to learn but you will spend much more time investing in it.

> learn both of them, because I think it might be too difficult

If you're concerned about difficulty, consider learning Go first. Learning Rust is likely about as hard as learning both. Learning both takes longer but the Go part is not nearly as difficult (until you get deep into Go which isn't often needed).
You do stop having a typical mammalian brain. This seems no more subjective than Moore's Law, for one, or Conway's Law for another.
>> Adding features to a spec'd standard is a horribly slow process

Only if your not one of the Big Tech companies....

If your Google you just say "We are doing this, you can either add it to the spec or not, but we are doing it"

Then it magically gets added the spec very quickly
Another potential benefit of this sort of early detection would be the ability to more effectively test interventions that might have little effect on more advanced cancers.

That could help direct research into the development of cancers at its earliest stages, and potentially pave the way for more effective prevention.
I use Hugo now for my blog. But I do have to admit that Medium's mobile app is really great for writing posts.

In an ideal world, I would have that interface to write my markdown on the phone. It would encourage me to write more. I could start a draft of something when a thought occurs to me and finish it up later at home.
Really long article but this is the crux:

> The emotional bond and the collaboration between client and therapist – called the alliance – have emerged as a strong predictor of improvement, even in therapies that don’t emphasise relational factors.

> Until recently, most studies of this alliance could show only that it correlates with better mental health in clients, but advances in research methods now find evidence for a causal link, suggesting that the therapy relationship might indeed be healing. Similarly, research into the traits of effective therapists has revealed that their greater experience with or a stricter adherence to a specific approach do not lead to improved outcomes whereas empathy, warmth, hopefulness and emotional expressiveness do.
Related: https://www.joelonsoftware.com/2000/10/02/painless-functiona...

My opinion:

If you don't specify things in a separate document in the form of text and pictures, then you end up doing it anyway but ad-hoc.

Your "non-spec" now leaks into multiple tools and channels that likely don't talk to one another: emails, instant messages, file storage, notes, phone calls & discussions (AKA in your head/memory), Trello/Asana/Jira etc. and in peoples imaginations and expectations.

A specification is just the things you do anyway but instead written down in a single maintained place. You can source control it and iteratively change it. All the parties can pull it and look at it before/during/after iterations and discussions.

A spec doesn't need to be set in stone at all. It can grow/shrink/change iteratively with the thing you build. It can also define things that you specifically shouldn't do or worry about.

A "design doc" seems to be something like that with a different name?

Also a specification can help to communicate much more clearly, since you end up defining a vocabulary for processes, UI elements, technical components and so on.

Tools I find useful to do this:

- markdown + css + some tool to convert it to html/pdf

- graphviz, especially for state-machines and decision trees, I prefer output as SVG rather than PNG.

- UML diagrams or similar if applicable
The pumps alone that can deliver that volume are an engineering marvel
The quote below is what has stayed with me from the moment Anders Tegnell started appearing in news items online. It's from an interview published in 21 April 2020 in Nature:

The big debate we are facing right now is around care homes for older people, where we registered very unfortunate outbreaks of the coronavirus. This accounts for Sweden’s higher death rate, compared with our neighbours. Investigations are ongoing, because we must understand which reccommendations have not been followed, and why.

https://www.nature.com/articles/d41586-020-01098-x

The quote betrays a complete and utter unwillingness to assume any responsibility for the Swedish Publich Health Agency's "recommendations" and blame everything on others for failing to follow them.

Note that the PHA's "recommendations" were based on an equally recalcitrant unwillingness to accept that asymptomatic carriers can spread the disease. From the same article:

There is a possibility that asymptomatics might be contagious, and some recent studies indicate that. But the amount of spread is probably fairly small compared to people who show symptoms. In the normal distribution of a bell curve asymptomatics sit at the margin, whereas most of the curve is occupied by symptomatics, the ones that we really need to stop.

Because of this unwillingness to consider unsymptomatic carriers' potential for spreading the disease, the Swedish PHA's recommendations for care home workers were inadequate to protect care home residents:

The agency’s advice to those managing and working at nursing homes, like its policy towards coronavirus in general, has been based on its judgment that the “spread from those without symptoms is responsible for a very limited share” of those who get infected.

Its advice to the care workers and nurses looking after older people such as Bondesson’s 69-year-old mother is that they should not wear protective masks or use other protective equipment unless they are dealing with a resident in the home they have reason to suspect is infected.

Otherwise the central protective measure in place is that staff should stay home if they detect any symptoms in themselves.

https://www.theguardian.com/world/2020/apr/19/anger-in-swede...
Having an S3 Bucket with writing permissions to anyone is a major fuck-up. I know many people open buckets to the world at the read-level for whatever reason. I do that myself for static websites. But also writing permissions?

This requires a Bucket Policy that is written explicitly to allow this. I don't want to make assumptions because of course we don't know all the information and I personally know very little about infosec, but that sounds very strange.

Why would you do that? I assume the SDK gets uploaded from a secure environment that has the credentials to upload objects, so there's no legitimate reason to have writing permissions open to the world.
It's a bit of a tortured metaphor, but I think RPG stats are a fairly good analogy. Most people or characters get their stats distributed fairly evenly, and get about the same amount of points to distribute, whereas some people get their stats distributed unevenly or have more or less points to distribute. Someone with a high number of points also distributed unevenly enough to excel in one area would be a genius.
This resists mechanical forces, but what about EDM milling or plasma ?
Agree that the lower funding amount doesn't make sense and will probably further disadvantage minority and other founders. However, the problem identified seems real where the culture seems to be shifting from attracting relentless company builders to those seeking another checkbox on their Linkedin profile.

This is also why other accelerators are emerging that aim to capture the YC essence of old (OnDeck & Jeff Morriss Jr.'s new initiative)
> Yeah, in reality its like complaining someone "broke" into your care when you left all of your doors open.

And you wouldn't get much sympathy, but this is a legally viable complaint. When my car was stolen, the thief was charged for theft, but his girlfriend who was joyriding with him was charged for criminal trespass. Just being in the car when you don't have permission is illegal.
Slightly off topic, but when you share this article via social media, the page title becomes:

"Slack Files EU Competition Complaint Against Microsoft - Several People Are Typing" [1]

Due to the og:title tag being different.

---

[1] Emphasis mine.
Guess it's time to share this again. "Cancer screening has never been shown to save lives" - Oncologist Vinay Prasad. Detection is not the problem. It's what to do once you find it. Iatrogenic harms are real.

https://www.bmj.com/content/352/bmj.h6080

With better testing, we might be able to save some people, but we might also be subjecting a great deal more people to harms through unnecessary treatment and psychological trauma.
Posted this deeper in thread, also noting up here:

Just serve your markdown git repo using Caddy.

https://caddyserver.com/docs/markdown

”Caddy is both a flexible, efficient static file server and a powerful, scalable reverse proxy. Use it to serve your static site with compression, template evaluation, Markdown rendering, and more.”

https://caddyserver.com/

Here’s a blog on doing this with the older version of Caddy:

https://blog.thomaspuppe.de/static-sites-from-markdown-with-...

You get a lot of other “just works” goodness too.
Every country that tried full eradication has succeeded (Vietnam, New Zealand, Taiwan, Mongolia, etc). Trying to live with it does not work.
It'd be great to have an app on Android that applies this to every photo I take with my camera.
Yes, in Sweden the problem was the nursing homes and they were run (and still are run) badly. The other measures that could have been done (within the covid response itself) would probably not have helped this, goes the argument (but certainly a major overhaul of how the nursing homes are staffed and run would have helped - that would never have been possible in the short timeframe though).
This is the Javascript SDK so checking any website which uses it would be enough to see if the modification is present.
I am working on some code I last touched 12 years ago. I think good documentation is essential, it saves time in the long run. Knowing the why is very helpful.
Student accuses Australia of misleading investors on climate risk
Half the time these are written after the fact (or updated after major changes), so they're often used as shitty documentation. I don't disagree with them, in principle, but I've yet to really see the benefit of them. The adage "In preparing for battle I have always found that plans are useless, but planning is indispensable" seems to apply.
But in this example - stomach cancer - you could just skip the test and do a routine endoscopy and get some tissue samples. You’d have a much higher confidence in the result.

Reminds me a bit of the PSA test for prostate cancer. More of an early warning, but with the weak predictability, doctors are moving away from routine PSA tests.
To add on top of it, majority of graduate students are from countries like India and China and their life/career is tied to F1 visa status which make students even more vulnerable to disclose any sincere/legit info. about the program they are in.
>impossible to be productive using Slack or Teams alone. The ultimate power move is to write things up in a company wiki

Every Team, by default, has a Posts, Files, and Wiki tab. Designing a way to roll up those Wiki pages, like they do with Sharepoint hubs, would be a good move.
Exactly my point. The executions listed there were not done just for homosexuality, but were associated with other crimes including child molestation and murder.
I’m sure this is what the world wants but....

I love the Osprey! One of my all time favorite aircraft. I probably wouldn’t have bought this, so I guess they don’t care what I think, but I thought this was super cool.
I would guess one change would be a higher metabolic demand on glucose + oxygen, beyond that which the body can supply. Like a CPU that requires more peak power than its motherboard VRMs + PSU are capable of drawing.

The brain already has a large metabolic cost, even dominating the total metabolic needs of the body during early development (https://www.pnas.org/content/111/36/13010).

I've long held a suspicion that the main reason IQ has a normal distribution is not anything to do with brain architecture per se (i.e. it's not a polygenetic trait that builds some brains out of better or worse genes than others) but rather that the brain is limited in its ability to become more complex by a proportional need for metabolic energy; and that the metabolic efficiency of human bodies is a polygenetic trait, such that the body systems required for metabolism are built from better or worse genes, that will thus get energy to the brain more or less efficiently. (This would explain why the brains of higher-IQ people don't look any different under histological analysis—there's nothing genetically or epigenetically different in them, in terms of what proteins are being expressed. Brains are brains. The differences that determine brain complexity would be elsewhere, in their bodies!)

This also, in my thinking, explains the Flynn effect: anything that we as a civilization do to get rid of an obstacle in the way of our metabolism—e.g. decreasing parasite load, stopping exposure to environmental toxins like lead or pollution, fortifying foods with vitamins, etc.—should bring the average human living within civilization ever closer to "peak performance" of the human body's metabolic system, and thus give the brain more "headroom" [hah!] to become more complex.

Of course, the Flynn effect says that this only happens to new generations (who grow up with such advances in place); not to older people (who don't grow up with such advances, but are exposed to them later in life.) I would suppose we just have some epigenetic triggers that "give up" on brain complexification after a certain point in life, probably assuming that whatever equilibrium the brain has reached between growth and apoptosis-through-energy-starvation by that point, is the final limit.

Alternately, as proposed here (https://en.wikipedia.org/wiki/Synaptic_pruning#Energy_saving...), the body might do well-enough to feed the brain when that's the body's only job; but not well-enough to feed the brain when both the brain and the sexual organs (and all descendent demands, e.g. pregnancy) are fighting over metabolic energy. So the "throttle" on the brain's complexification becomes "choked off" during puberty, such that the resultant metabolic energy can be reserved for reproduction. (Under that hypothesis, preventing puberty might result in higher-IQ people. It apparently worked in rats!)
I imagine that there will be a longitudinal trial for this test. Individuals will be tested at set intervals and the test results will be correlated with clinical outcomes. It is possible that enough blood samples have already been collected such these same correlates could be identified retrospectively.
Come on, this submission has been here for barely half an hour and hasn't cleared the upvote threshold to reach the front page. The people you complain about barely had a chance to get to it and start flagging.

Edit: for example, a similar ad 3 hours ago was flagged: https://news.ycombinator.com/item?id=23916184
Those 20 somethings as potential founders was what other investment companies overlooked and partly made YC new and different. That was one of their innovations. Before YC investment companies were always looking at uni professors and execs dropping out of corporations.

Changing this focus -- to focus on older more experienced invidividuals is changing YC imo. Less social justice more hackery/building stuff people might like would be a positive move for YC and the audience. I don't think we're in such a climate to discuss this though.
There are a variety of online whiteboards. Miro is one the company I work at uses.

There's a valid argument in the annoyance of audio latency for this making it not as efficient as physical presence but it's still a very workable solution and gets most of the way there.
haha yea I saw that, looks really good. thank you!
Microsoft has basically a monopoly on enterprise tools such as word/excel/etc. Apple does not.
Something I didn't see someone mentioning: Microsoft is moving everyone from Skype for Business over to Teams. Any enterprise customer will have to migrate. Skype for Business is quite different from Skype itself, basically a marketing thing.

Moving enterprise customers over from a chat&screen sharing app to teams is quite a change. There's loads more functionality, options, etc. I don't think if you had Skype for Business before you'd ever consider anything such as Slack or similar.

From what I noticed Skype for Business is used often within enterprise companies.
Good.

Companies are learning what happens when you morally outrage those on the right side of history.
"There are very few laws in biology." This is something a bio professor told me long ago.
While this strikes me as possibly true, maybe even probably true, I would prefer to see actual simple data about this. Sure it would be hard to get but here's the schema I imagine would be needed.

Founder ID,

Founder bank account balance average during company's first year,

Founder health metrics array [acute visits to hospital or clinic for diet/mental health issues],

Outcome of company

---

If we notice that founders with low bank balances, lots of health events in their life, and unsuccessful business outcomes are popping up in the data, and then conversely founders with 100k in their personal bank on day 1 are never visiting the hospital and their companies are doing fine, then I think we could call check size a definitive contributing factor. This would fly in the face of "ramen profitability" as a virtue.

EDIT: and i think there are enougg startups out there (40,000 probably??? ask crunchbase) to have a meaningful sample size
Or anyone that has to buy insulin...