skysight-inc/HackerNews huggingface dataset:
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>Haem Definition and Examples - Biology Online Dictionary

>What does haem mean in biology?

haem. 1. (Science: biochemistry) compounds of iron complexed in a porphyrin (tetrapyrrole) ring that differ in side chain composition.
Racket has a much more advanced macro system than scheme's traditional syntax-case.
"too much" implies that it is bad; otherwise, it wouldn't be too much.
Yes, this is one of the reasons that I decided to use Joplin: it's Open Source and cross-platform. I never want my notes to be locked to one or two platforms.
Not a CS researcher but I would say that advisor is extremely important, but also within the field you are interested in. A good advisor can win you over only so much - there are people who switch advisors because of research topic reasons too (not just because they feel abused). Though if you are in the topic you want to continue in, a good advisor can make a huge, huge difference in terms of getting the most out of you and also promoting you among his /her peers.

To some extent I would not choose based on current market trends - if you want to go to grad school, you're looking at a job market many years down the road (esp. if you do a PhD). However, "saturation" is an issue and this could be demotivating. You definitely don't want to choose a boring topic. If "Bioinformatic/quantum computing" is interesting to you but you're not sure of its applicability/potential but you find it interesting enough to study, I would say this is the perfect field for you to study. Maybe a "deep learning" type revolution is around the corner - or maybe you're going to be part of making it happen.

Not to say market trends are unimportant, but as elonmollusc says, you can end up changing your field of research later - so you should some extent study what interests you most at each moment in time.
> add screenshots/images, links, etc

A printer and a url shortened would replace these
Go WASM Playground
No, the problem is you have to discount that audience by the risk of it getting destroyed overnight by an unsympathetic Twitter admin/moderator. And by the high difficulty of cashing it out. And by deboosting algorithms that will limit your reach.

Accounting for this, I don't think it's a stretch to say that having 1,000 people on a platform you control is much better than 10,000 Twitter "followers". Maybe even 100,000 depending on how much Twitter likes you.
When people make fun of leftpad they are not talking about babel and webpack.

The bloat is a lot about the lack of a standard library in JS. Or rather, too many of the damn things. That and an inconsistent and unpredictable type system.
The Pauli exclusion principle is just a fancy way of saying two electrons (later extended to fermions) can't be in the same place at the same time
From my experience there are two tiers of international student. There are the ones who emigrate in late middle school/early high school to get permanent residency before entering university (and thus paying domestic tuition) and those who come over right at the beginning of university. The latter category pay exorbitant tuition and, from what I’ve seen, drive fancy cars and wear luxury designer brands. These kids have more money than they know what to do with. Their parents are likely to be at least somewhat involved in the CCP and so it makes sense that they’d be unimpressed with their western peers.
From the abstract: "we identify a pathway worthy of further study: haem metabolism."
"association" = misleading?
The government might claim that it represents the interests of the people but they do not seem to put their words into actions. Would you support teachers employed by the state not having unions?
My first job out of college in NYC paid $80k, and I am not a particularly good, money hungry, or hard working developer. I was able to get that to $100k within a year (age 23) via negotiation.

You're getting taken advantage of. Even if you're 22 (and if you are, I'd delay having a family tbh), you could probably get to six figures by applying to another job.

I understand times seem tough but honestly my company and others have been hiring just as much if not more. No offense to any service workers but a software engineer in NYC having to Instacart is... not right.
It's a marketing term for a technique you could probably learn for much less in any wrestling or jujitsu gym for thousands of years, but isn't as defensible in court.
I'll take this one :)

Not even a hello world supports Windows 95 when compiled by MSVC 2005, and it's just because of a call to IsDebuggerPresent() in the standard library's startup code. To work around this, I overrode the definition of that function in one of WA's .cpp modules, to delay-load the real function, and return FALSE if it doesn't exist:

extern "C" __declspec(noinline) BOOL WINAPI _imp__IsDebuggerPresent(VOID)
{
typedef BOOL (WINAPI *IsDebuggerPresent_t)(VOID);
if (HMODULE lib = GetModuleHandle("KERNEL32.dll"))
if (IsDebuggerPresent_t proc = (IsDebuggerPresent_t)GetProcAddress(lib, "IsDebuggerPresent"))
return proc();
return FALSE;
}

(Many more hacks like this would be necessary if using a later version of MSVC. So I use Daffodil to allow using a later version of Visual Studio while still using Visual C++ 2005 for the actual compiling.)

Other than that, it was just a matter of identifying all the API calls requiring Windows 98 or later and replacing them with their Windows 95 equivalents. In cases where this would mean sacrificing functionality, that meant delay-loading the Windows 98-or-later version and falling back to the Windows 95 version if necessary, such as with GetDiskFreeSpaceEx() vs. GetDiskFreeSpace().
For some reason I also thought this was about making the strips for fun. But this has nothing to do with making, it's just assembling someone else's strips...

I was just curious to see how one would go about making strips. Order a bunch of wires and hand solder some SMD LEDs? Get a FFC made by a random PCB manufacturer and solder LEDs on those? Make some sort of mould and use one of those odd silver glue connections to an existing wire strip? Order a bare strip and use solder paste and a heat gun or hot air soldering station to solder them on and then dip the whole strip in transparent elastic resin?

Instead of having some curiosity itch scratched it just makes it worse.
The TS100 and the subsequent TS80 soldering irons were innovative for a few reasons. The heating element is in the tip rather than the body of the iron. This means it can reach a high temperature (e.g. 350C) using much less power than a traditional iron. This means that it can be powered with a USB power bank and makes it a great iron for using off the grid or in the field. This also means it's very lightweight which makes it easier to handle for delicate soldering work. Even if you're working at your desk, being able to power it with a portable power bank means you can more easily move the power cable so it does not get in the way (also I believe the TS80 comes with a silicone USB cable which is really flexible and easy to manipulate). Another nice feature is that it has an accelerometer which means it can automatically drop to a lower temperature when it's placed down making it a bit safer. Lastly, the firmware can be replaced and people have added features such as a temperature boost mode, power level monitoring and so on: https://github.com/Ralim/ts100

Normally, you can get these irons for $80-$90 so a $24.99 iron that uses the same tips and software would be an absolute bargain.
> if someone was a ___ or a ___ I would be really uninterested in their opinions on pretty much anything because they're obviously ___

Dismissing one’s ideas based on group membership is a terrible strategy for truth-seeking. It’s a root of all kinds of problems we see with team-based politics where both sides have turned their brain off and largely accept the entire slate of talking points their side serves up.

It also borders on the definition of bigotry.
Spycraft is covert. Replacing the culture of a nation with one's own is imperialism. A couple centuries ago it used to be done by force. Now it's done via economic means.

It's interesting how China is turning the globalist policies of developed countries into power. The government bans a cartoon character due to memes and suddenly lots of huge companies start censoring themselves out of fear. The US may have freedom of speech but it doesn't matter if China is the bigger market.
It really worries me that people try to understand economics or society by starting with how things should be and labeling anything else "wrong". We've had 1000s of cults and ideologies on this basis. Today we get weird long diatribes and books pushing conspiracy theories.

The truth is humans are an efficient market: if someone finds a better way of doing things, it spreads and takes over, this are the way they are because we tried other ways and they were worse. If something is bad, its either because we can't get rid of it without making other things worse or because people themselves are bad and like it this way.

This theory is very boring, but overwhelmingly accurate imho.
No, that is literally how many people think on the daily.
> Switching to the Fediverse is also an option

Really only if the people you want to interact with on Twitter are either already on the Fediverse or can be persuaded to move across. In my experience, they're not and they won't be. Which is why I still have an active Twitter account.
I just hopped into their Discord server and recognized so many people from those days: BuzZz, Drizzt, Ironman, Off Kilter, Star Scream, Windsong, Erasmus, Kelos, Nostradaemon, PAMSWEETS, Tember, Stormy, RavenXR.

All those people helped to profoundly shape my childhood, of which ~7 years was spent playing this game.

I really am grateful you posted this link. Thank you again. :)
For these kinds of articles, it is important to remember that correlation does not imply causation.
We've been using CloudFlare's SSL for SaaS [1] offering for the last year, and have nothing but good things to say. You also get the rate limiting and other protections you'd expect from CloudFlare. It's been great not having to worry about CSRs and cert renewals as we've scaled out. Although, we _did_ go down the other day as part of their outage.

[1]https://www.cloudflare.com/ssl-for-saas-providers/
"Multivariate MR of iron-related traits on healthspan, parental lifespan, and longevity shows a protective effect for transferrin and a deleterious effect for serum iron."

not in life sciences too, and my interpretation of the above phrase is "if your body iron processing machine works well - good, if not - then bad" which i'd say would be pretty expected, and in general article sounds like there is positive correlation between well working iron related metabolism and longevity which seems not that surprising. They don't seem to address the machinery and nature of that correlation.
Why would the streamers even want the proceeds from fraudulent transactions? It's dirty money no matter how you look at it.
I was just about to come here and mention Micro.blog, and I'm impressed someone beat me to it. :) Of course, you can do it for even more cheaply than that if you're a bit technically savvy and willing to put in the effort. I like the idea of newsletters, but they strike me as a different kind of solution. Micro.blog is a great compromise between being Twitter-like and still allowing longer blog posts. (And still cross-posting to Twitter, to boot).

It's also worth noting that version 3 of the Ghost blogging platform has a newsletter system integrated into it, so if you fall into the "a bit technically savvy and willing to put in the effort" category, you can use that to put together a newsletter for less than $30 a month. And if you want a newsletter but still want someone else to take care of it for you, there's Substack, which lets you publish newsletters for free and, if you want to go paid, charges 10% plus credit card processing fees, which may end up working out to be cheaper than $30 a month for a lot of low-volume folks.

(My own Microblog: https://micro.coyotetracks.org)
Not CS but I went to a lot of seminars and then picked the topic and advisor based on that.
One can believe it test scores correlate with innate intelligence and also think that they are a flawed measurement tool
How Not to Deal with Murder in Space
> Polling has repeatedly shown very widespread public confusion over what Brexit will actually do.

I can believe that.

> Even many remain voters don’t realise all the downsides.

I can believe that, but what makes the confusion one-way? i.e. do leave voters realise all the upsides?
It's also a case of "never use a debit card".

"debit cards" have far fewer protections and opportunities for chargebacks than credit cards in the US.
Who says doing nothing ? There are lot of thing that can be done : vaccine research, method of treatment improvement, promote hygiene, increase medical capacity (if needed), etc
I'd start a disco band, hire Donna Summers as my lead singer, get rich, and retire at 30.
Blood donations are the modern positive equivalent.
If anyone wants an amuse gueule for the thought of Peter Thiel, this is a good one: https://www.youtube.com/watch?v=iRleB034EC8

So many interesting, fundamental topics.
It's also very easy to create crappy lighting conditions because people think of light to be just 'light' which it isn't.
Wow, I think this is a problem with you. Feynman is smiling through most of his answer. His diversion at the start is just to explain to his interviewer how wide and deep the question “why” can go.
Too many out of office style autoresponders reply to everything, even mail properly marked to not generate autoresponders / marking mail so it doesn't trigger causes it to get flagged as spam.
He's probably loaded, which is why he can pay for this (instead of charging back) and why the teen didn't think this was such a big deal.
dang, I was clearly joking...
They say they do, but I'd say they didn't do that properly.

Quoting the relevant part for you that lead me to this conclusion:

> "For one, there are currently no widely accepted standards for measuring healthspan. Zenin et al. define healthspan based on the incidence of the eight most common diseases increasing exponentially in incidence with age in their sample. "

> "Recent estimates suggest the genetic components of both human lifespan (i.e. the number of years lived) and healthspan (the number of years lived in good health free of morbidities) are only around 10%"

> "Parental lifespan correlates strongly with both healthspan (rg = 0.70; SE = 0.04) and longevity (rg = 0.81; SE = 0.08), while healthspan and longevity show a weaker correlation with each other (rg = 0.51; SE = 0.09)"

The authors may pretend they studied healthspan, but I'd rather say they studied biased data (as death is well reported, while autonomy is harder to asses according to their own words), on something poorly correlated with healthspan, which even if we assume perfect correlation can only explain about 10% of the difference.

> healthspan correlated more strongly with metabolic traits (such as type 2 diabetes) than the other studies, and showed negative genetic correlations with depression and cancers, especially melanoma

So I would not call the article rubbish, but I would be careful to extrapolate that iron matters so much:

> These correlation estimates ranged from 0.013 between healthspan and longevity to 0.094 between healthspan and parental lifespan, reflecting a small degree of sample overlap and/or phenotypic correlation

Indeed, parental lifespan may explain more! Even better, look at the coefficient in table 3:

> https://www.nature.com/articles/s41467-020-17312-3/tables/3

βlongevity is 5x more than βhealthspan , and one coefficient even changes sign (ferritin) possibly due to haemochromatosis (I'm too lazy to check, I've already spent too much time on this article) so I wouldn't jump to conclusions
I don't have a clue about the math, but I liked the puns in the preface to Knuth's "Concrete Mathematics":

"When [Knuth] taught Concrete Mathematics at Stanford for the first time, he explained the somewhat strange title by saying that it was his attempt to teach a math course that was hard instead of soft. He announced that,
contrary to the expectations of some of his colleagues, he was not going to teach the Theory of Aggregates, nor Stone's Embedding Theorem, nor even the Stone-Čech compactification. (Several students from the civil engineering department got up and quietly left the room.)"

https://en.wikipedia.org/wiki/Stone%E2%80%93%C4%8Cech_compac...
My reaction to this; a journey.

Hey I've been looking for something like this.

Ahh local first, and markdown. I might like this.

Fuzzy search? I've gotta try this!

Wait, is this electron?

Please don't be electron, please don't be electron, please don't be electron!

> Made ontop of VS Code

Well, shit I'm out. Damnit!

~fin~

I miss real applications...
Due to them saying that "the association might be due to an already-known correlation to haemochromatosis" I'm assuming they didn't have the data to correlate haemochromatosis to the data.

Haemochromatosis is a genetic disorder where individuals are unable to get rid of excess iron. If properly diagnosed, this is easily treatable with bloodletting (blood donation in this century :-)

Haemochromatosis is the sort of genetic disease that could really screw with data like this. Undiagnosed haemocromatosis leads to early death....so the correlation of excess iron to longevity should be treated as a weak piece of evidence until we can exclude people with the genetic disorder.
haem = ~ iron
"Debit card" not "credit card".

That's one of the problems. People think you get the same level of protection on a debit card that you do on a credit card, and that's simply not true.

In the US, never use debit cards. Always use a credit card.
You come off like a shill. The majority of new drug development is the result of publicly funded research. Drug companies mine that research, and in many cases their main contribution is ramming the drug through the FDA approval pipeline. The university will also take a big cut, even though they were given (mostly public) grants to do the research.

Drug development is probably one of the best targets for socialization. That would reduce the number of stupid, pointless drugs that get developed. How many billions have been wasted to produce ~20 different anti-depressants, none of which does more than slightly outperform placebo?
Effective automatic theorem proving would make software much safer as well. Right now it's too much time to bother verifying so much code, even if somebody would be capable of doing it.
Really? So soon? Can you be more explicit?
I am from Siberia (Omsk, Russia). While some of the things in this article are true (distrust for Moscow, openness and straightforwardness, feeling separated from the rest of Russia), I want to note that there always were hot summers in Siberia. While the current heatwave is beating records, when you see +38C in Verkhoyansk, you should keep in mind that there weren’t Arctic temperatures in summer, +35C happened quite routinely there). The changes are not enough to form “a new identity”... I think.

Also, one thing that Russian powers-that-be absolutely cannot stand is separatism. We always joked that “it’s time to ditch Moscow” and the like, but any real attempt will be met by crushing force, nobody has any illusions about that.
Actually I don’t think it is. Nobody thinks the guy that installs my fence designed the Golden Gate Bridge.
Probably still looking up in quite a few fields(technology, education), but on society/core value aspect it’s been shaky
I use git as well to track my notes, I just haven't found a good editor yet which is equally as important. Sublime Text or any code editor works fine enough for Markdown, but I really miss the ability to have hyperlinks in my notes. Markdown links are just extremely ugly to look at and overly verbose.
Am I reading this wrong or is this just a case of a person stealing money/commuting fraud, and every institution involved being ready to act if charges are pushed, but a mother wanting to shield her son by not pushing charges for the crime he admittedly committed... but still wanting the institutions to act as though changes had been pushed?

I get that she wants to protect her kid, but at this point she really has to sit down and make the decision and figure out if she wants the 20k and will press charges for what literally transpired. Or if she would prefer to protect her kid and pretend nothing happened.
Wanting to go both ways and have the receivers of the funds individually reimbursed her just so she can pretend her son didn’t steel the funds out of her account by lifting her password just seems utterly absurd.
The technology should exist by now for a decentralized twitter right? Resorting to email newsletters seems very clunky. Couldn't there be something that uses a bittorrent-like protocol, where the followers support the network for whomever they're following?
Ask HN: Why are cover music so popular in certain countries?
I have travelled the world and been exposed to music which has been made into cover tracks, and never ever been played in its original form.

Why is that? Is it rights? Is it a scam of some sort?

Cheers
That is indeed what I meant; I had to create debootstraps to even get it running on my laptop. And many of the gem updates broke the apis completely for no reason (move fast and don’t care?) I do not know: I remember a security update where the new version renamed most of the api methods while there was no reason to do so. I understand you can add new methods to keep backward compat; here they actually renamed functions so it was not backwards compatible and you had to change everything.

Simply put; we can cry about java or c# or php (raw php: not laravel; it has the same issues) but I can run 15 year old code on my current Ubuntu and it works fine. Maybe I need to change a few things but I do not have to rewrite a lot of it; it is more find/replace than anything. The feeling that software has to work in 50 years is important. Incremental updates are expensive and not needed for most companies, so software needs to support major version updates over decades. We know that now...
> Cargo pants aren’t office-wear

That sounds like an awfully pretentious office, that I personally would never agree to work in.
I think that's my point. If the structure of the soundbite doesn't argue for its case then it's a useful short-hand for people who know the economic definitions, but it otherwise isn't enlightening. If the purpose of making the distinction between productive and unproductive activity is to inform, then a reason needs to be given for activities being called one or the other.

Without that reason, the framing looks more like politics than economics.

As for "provided": leaving aside the moral question of how the status quo obtained (which, I'll grant, was likely not moral at all), the landlord has land that can be used for farming, but also for polo or fox hunting or whatever. The farmers have time and energy that can be used for farming, but also for football and arm-wrestling competitions etc. I'm not saying they're the same, I'm just saying that if they're different we need to do more than just assert it.