> As we go on you reference Fung (and defend him) a fair bit

I defend Jason Fung because he's one of the few in this area of science and medicine who has gone to the trouble of writing books that ordinary people can understand, and yet still have some scientific rigor. I could cite innumerable scientific papers that very few have the training to read, or the one author who took the time to write something anyone literate can at least follow along with.

There are hundreds if not thousands of researchers and practitioners in this area, so it is convenient to point to someone that anybody literate can read and rely on. His books (several of them overlap greatly) cite hundreds of papers, so that work mostly a compilation of other's work (as it should be).

> He does not hold (to my knowledge) a PhD nor has he published any peer-reviewed studies.

From his books there are some references to his published scientific work on fasting, diabetes, CKD, and so on. See also
https://scholar.google.com/scholar?q=jason+fung+intermittent... , https://scholar.google.com/scholar?q=jason+fung+diabetes ,
https://scholar.google.com/scholar?q=jason+fung+ckd ,
and https://scholar.google.com/scholar?q=jason+fung+pcos for examples.

I'm not sure what a PhD has to do with anything, most of my scientific work was published before I got mine, or even started it, as is common in industry and applied sciences.

> That being said - the link you provided on FFA is about cholesterol. I fail to see how that's relevant to discussion about FFA impact on insulin resistance?

I'm sorry you don't see the connection regarding FFA, perhaps you can re-read what he wrote and click through to the underlying reference to get a better idea (the title is "Fat Oxidation, Body Composition and Insulin Sensitivity in Diabetic and Normoglycaemic Obese Adults 5 Years After Weight Loss"). I couldn't find the text of Fung's book online, but the other paper he references in this connection is "The role of fatty acids in insulin resistance" (2015) which I did find online, here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587882/ .

> Alas, to make my point. Obesity is certainly a multifaceted problem. Thermodynamics certainly matter, human psyche, inflammation, hormones - essentially all of that has its place. Looking from a systems point of view there's no reason (and probably there isn't one) to look for single causative agent though some certainly play a grater role. In my experience both time-restricted feeding, caloric restriction and macro restriction work and have their place depending on the individual. Generally as a rule IF and low-carb are certainly good ideas, I'm not a fan of keto for everything.

I agree in general. I think IF is fine, I'm favor of balanced diets not very low or high in anything in general, and I believe without regular blood work and expert supervision, keto is downright dangerous for most. Thermodynamics are present, true, but this is in practice perhaps not the most helpful perspective, since things like willpower, hunger, and sustainably maintaining a healthy diet matter more; the thermodynamic perspective fails to model the feedback control system that regulates the human behavior component. Nonetheless, I agree with the overall thrust of your comment.

Best regards, and thank you for the conversation!