skysight-inc/HackerNews huggingface dataset:
> Why is it hard?

It is an incredible mental balancing act when you think about it. Your goal is to get some information into someone's head. To do that, you need to actually simulate their brain using yours. You have to think about how that person learns, what they already know, and how to incrementally build up your information in a way that makes sense to them. You have to think about what words and idioms they're familiar with, whether they learn top-down or bottom-up, etc.

In order to get into their mindset, you have to temporarily pretend to not know the thing you are explaining. At the same time, you are explaining it, so you have to simultaneously hold that very same thing in the forefront of your mind.

Now consider that each potential reader learns differently and knows different things so when imagining your audience, you have to do the whole process above in parallel for a number of different imagined audiences.

Doing this well requires a lot of theory of mind skill, and that's something that I think a lot of technical people are not very good at. My experience is that a lot of people who are drawn to tech are that way because they've found it easier to get along with machines because machines "make sense" and are simpler, which to me points to less theory of mind ability.
It's a low budget film, but I agree that it's worth watching.. especially for the socio/psychology elements.
We were doing this, but the lockdowns pretty much blew a hole in it. It's difficult to maintain eating this kind of food without going to the store every 2-3 days or accidentally end up throwing out massive amounts of food every once in a while.
I've been using Tasty. Quick videos showing all the steps and the how it's supposed to look like along the way. That's the only way I can accept recipes anymore.
Given how much people focus on looking youthful, it's probably reasonable to assume that appearing youthful has historically been advantageous, from a reproductive point of view. Which would lead such a mutation to spread pretty rapidly throughout the population.
Someone I work with looks very youthful for their actual age, and that isn't always a good thing.

When the team went on an offsite morale event jet skiing, he was told by the proprietor that he couldn't participate because their policy requires you to be at least 16 years old. He was 27 at the time. He never lived that down with his peers. When he tries to go to a bar with friends, he's sometimes accused of trying to pass off a fake ID. These experiences are deeply embarrassing for him.

Imagine trying to get promoted to a senior director position at a company while looking like you are fresh out of college. In that case ageism takes a different meaning.
Hmm. Well the epigenetic aging clock effects are hard to interpret, but they also show recovery of cognitive performance in aged rats treated with their magic plasma fraction. That is kind of exciting.

Nevertheless, there are significant conflicts of interest going on, so confirmatory studies by independent bodies in animal models are required. Then there are the human studies. They obviously want to use the epigenetic clock as a surrogate endpoint in humans, so the trial can be completed in a short time frame. Not sure about that, this is a fairly complicated surrogate endpoint we are talking about. Some more relevant biomarkers of aging in humans which incorporate functional readouts would be required at the very least.

https://www.biorxiv.org/content/10.1101/2020.05.07.082917v1....
I think the real innovation here is that this was done on just a few minutes of training data, opening up the possibility for all kinds of effects / amps to be modeled through this same method somewhat easily. I'm not sure how current DSPs are designed, but this is likely orders of magnitude more simple than designing the audio transformations (digital or analog) manually.
I don't know about vacation towns but given expensive urban cites I expect to see large drops in prices. Given covid-19 and its mindset it no longer makes sense to live in densely crowded expensive metro areas anymore. With large tech companies finally waking up to the fact that remote work actually works expect to see a huge exodus of people from these expensive regions. With all the restaurants and museums closed and really no outside space they don't have much to offer except high taxes and crowds. Also if a engineer can get roughly the same pay but work where they can buy a house instead of have 3 roommates in a 5k a month apt. which would they choose?
Death and aging is a feature of evolution. These features evolved to further enable evolution and allow it to iterate more quickly. Species that iterated more quickly, and therefore evolved more quickly were more successful. Features that are deliberately evolved exist within many different genes as a mechanism to protect the feature, this is why dropout works so well on neural networks.
If you want neutralizing antibodies you can do serum virus neutralization assay. It's more complicated and takes longer.

Testing doesn't need to be 100% to be effective, but it does need to be better than random chance. A mixture of contact tracing, PCR testing, antibody testing and effective quarantines could be used to make the virus go away, but would require a coordinated strategy that the US has not attempted to implement, much to my dismay.
Let's say someone possessed that mutation. You have to remember prior to 200 years ago, your chances of dying from a disease, an accident, hunger, race, religion would have killed you anyway.
People who are immune to aging are not necessarily immune to a cannonball impacting their face.
The Abbott test may not be used everywhere. I've called them to confirm their labs local to me use the Abbott test and that's probably what you should do if you're looking to get this test. While it does not guarantee that they use the Abbott test in every region, you can see that they reference Abbott in the footnotes for question #3 in their FAQ on COVID-19 testing here: https://education.questdiagnostics.com/faq/FAQ219
In solenya it's very terse - you can use the HTML to JS converter to see the translation is pretty straightforward:
https://www.solenya.org/convert

Example code:

div ({ class: "form-group" },
label ({ for: "exampleFormControlSelect1" }, "Example select"),
select ({ class: "form-control", id: "exampleFormControlSelect1" },
option ("1"),
option ("2"),
option ("3"),
option ("4"),
option ("5")
)
)

In conjunction with typestyle, you never have to leave js/ts. Very clean.

The arguments against this approach usually boil down to the mistaken notion that "you're not separating concerns". The response is: separation of language != separation of concerns. No matter what you should still strive to reduce cyclomatic complexity. So you're still separating model, view, themes etc. And you're doing so using abstractions within the language, rather than relying on language and file boundaries. Notably in the reverse case, when you have unavoidable links between these layers (since no useful abstraction isn't leaky), the benefits of expressing everything in one language are considerable (e.g. when refactoring).
Poland caught in bizarre 'election', set for zero turnout
url=http://www.youtube.com/watch?v=V5bYDhZBFLA; youtube-dl -b $url; mplayer $(ls ${url##=}| tail -n1) -ss 00:57 -endpos 10 -vo gif89a:fps=5:output=output.gif -vf scale=400:300 -nosound

https://www.commandlinefu.com/commands/view/6110/create-an-a...
Many science fiction writers who envisioned generations born and passing away on spaceships making their intergalactic journey to their new home world would disagree.
I forgot to add, all the astronauts in I.S.S. that have been deployed more than a few months start experiencing permanent brain damage. Within 3 to 5 months, they have to start taking medication from glaucoma. Their brain starts expanding and puts pressure on the optic nerves. The condition is called SANS [1]. That bad part is, this condition does not get better when they return to earth.

To get to mars will take about 220 days. Unless we find a way to prevent the brain damage, anyone going there will be blind before they ever land.

[1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005826/
Hey HN,

Here's my latest project in the category of "ranking things based on social signals".

It looks at all (url-based) posts and comment mentions of Coursera courses on
Reddit, ranks each course based on Reddit score, and shows each course with
its top Reddit mentions.

Scoring each course is done with a slightly modified version of a simple popularity / age calculation.

course_score = sum(mention_scores) / course_age

I tried a number of other more nuanced ranking methods that try to surface "best" above "popular" (averages, confidence intervals, etc) but the simpler method thus far has seemed to produce the most "helpful" list. There are definitely still some bogies in there, but it seems to surface some interesting stuff.

You may be interested to compare this reddit top list to my previous similar project over Hacker News data (which also uses a significantly different scoring method): HN Academy [1].

Would love to get any comments and feedback.

[1]: https://yahnd.com/academy/
It was widely reported years ago. The future is already here it's just not affordable.

I remember talking about recent news that a few of us had heard about promising "young blood rejuvenation" with a bunch of random hicks in the woods of central Maine in the spring of 2014.
> You could accomplish much the same by using a "depth-1 network" and running an impulse through it

This would be true for a linear impulse response, however for this kind of effects you need both state/memory (like a convolution) and non-linearity (like a waveshaper), which is why people use RNN's and CNN's
Woah, Ethernet is nice to see on a Teensy!
Oh my. The mouth texture of figs, including the crunch of the seeds, is probably the single best thing about them.
The market can stay irrational longer than you can stay solvent, as the saying goes. Looking at fundamentals is not enough. Short and medium term price prediction is fundamentally an exercise in psychology.
So you can live longer, but what about cancer?
> UBI removes high marginal tax rate from poor households.

How so? I understand the "it's the same, just with less bureaucracy" camp wants everybody to get UBI, but everyone that's not below a certain threshold will essentially pay all of the UBI back via increased taxation.

So if you get $1000 in welfare now and you earn money, this changes the amount of welfare you receive. I understand that. How does that change if you get $1000 in UBI and for every buck you make, you'll pay essentiall $1 in taxes? You'll still only actually have more money when you're > $1000 on income.
Play Super Mario 64 on the web
Bayes theorem assuming 1% actual positive rate. If you test 1000 people, you will get roughly 10 positives and 1 false positive for a false positive rate of 10%.
To put it simply, a population with aging is more fit than a population without. The speed at which beneficial mutations in a population reach saturation in the gene pool is a function of the number of generations that have gone by. So we can expect some downward selective pressure on lifespan.
Maybe because people tend to reproduce fairly early in life (usually half of lifespan) so living an extra X years doesn't really allow you to have more children, and therefore the mutation of longer life doesn't get a huge enough advantage in natural selection?
I made a gatsby site about 2 years ago and it has been a nightmare to maintain, the build breaks for random reasons every time I come back to it.

Forcing everything to go through graphql is also a pain and adds an unnecessary indirection that requires a million extra dependencies.
While I agree that many switch onto adjacent roles, most SWEs do not do it by late 20s.
I’m been doing some Nintendo 64 development lately, and sometimes all ask the CEO at my workplace for advice or insights as he worked on Nintendo 64 games when he was younger.

It’s not uncommon for him to finish the conversation with noting that he worked on Sega Saturn before the Nintendo 64, and the former was difficult to work with due to its particular architecture.
Netflix and Google Are Poised to Dominate L.A. Real Estate
Emm, screen config not retained is an OS issue and not a laptop tbo

It is when the same company is making both.
That's a good point, but airplane transfers are pretty bad in terms of time efficiency. Every transfer adds at least another 1.5~2 hours to your journey, and is very uncomfortable because you need to get out and switch airplanes.

For your example, NYC to Miami, the distance is only around 1200 miles in total. Once you add in the extra time taken to travel by airplane and extra hours to make the transfer, the total time taken for the trip easily reaches 7 hours. And those are not a very comfortable 7 hours, with many stops, a lot of waiting in lines, etc.

A high speed train could make that same trip in 6 hours, and it would be 6 hours you can spend working in relative comfort. I know which option I would heavily prefer.
"Someone slipped up the distinction between years and generations and a legend was born" still seems enormously more probable than anomalous longevity existing but somehow never making it into the wider gene pool.
>...the bifurcation of the American dream. It used to be that working-class folks could reasonably aspire to buy a house. ...So unemployment is going to be bad for one part of America...

Housing as institutional investment and institutional land speculation is a condensed example of why stocks can rise during an economic catastrophe, why housing will become yet more unaffordable and what drives increasing inequality between wage earners and asset owners.

Redfin's stock has been part of the record breaking rally during the pandemic because the drop in housing prices that would have kept them somewhat in sync with a drop in income will instead be at least partially absorbed by Redfin and other speculators and so make housing even more unaffordable. As we know, the model is to offer a desperate seller a low price then keep the unit empty until a new higher price is met. So a unit stays empty longer than necessary, prices are kept high by a seller that can afford to do so (ie Redfin) and profit is made from widespread economic hardship.

In particular the housing crisis is not due to bifurcation between wage earners, it's a simple perpetual shift upward in housing prices that affects everyone who works for a living. Portraying it as bifurcation obfuscates the cause of the problem by creating a conflict between wage earners with different incomes while portraying the speculator's actions a inevitable, natural and harmless. But housing is not expensive because some people earn what they are worth, it is expensive because housing is used as investment.
Show HN: Tolon – Find Webpage Discussions on Hacker News, Reddit, etc.
I don't understand the economics of this. Professional programmers can easily make more than $65/hr. Reviewing someone else's code can take a lot of time: I spend 10+ hrs/week reviewing code for my team. How would the reviewers or the service make any money if this took off?

If the reviewers aren't really professional programmers this will just be the blind leading the blind. Better to learn how to search StackOverflow and how to ask good questions there if you want free crowd-sourced code reviews.
What if prevalence is 5% or 10%? Your alarming false positive rates vanish. No measure is ever going to work perfectly.
Partially, yes. But real estate is also typically very seasonal for many regions. Spring is traditionally the peak selling season, so you'll see an increase in homes hitting the market this time of year.
Not really.

A 10 mio poly mesh with a typical XYZW+RGBA+UV+UV2 = 12 float stream format would require 12x4x10 mio = 480 MB of GPU memory per copy. Skinning needs weights (200 MB) and at least a second copy, so one single 10 mio poly mesh would eat up about 1.3 GB of GPU memory.

So even with ray-traycing, optimizing models for a manageable polycount will remain crucially important.
I have this dilemma, where I am reluctant to pursue creating this "virtual" experience on SE. Years ago I spent a few months familiarizing myself with the engine and the programmable block limitations. It took me dozens of hours just to create the simplest of scripts. Learning curve, I know, but eventually I just did not think that I was adding that much value to society by spending hours of my own time and money trying to make a video game more engaging.

I still think about it often, the possibilities of the game engine, and perhaps it is because now it is spring time in my hemisphere and I feel guilty grinding away on a computer with some artificial goal, while the sun is beaming down all around me at a higher angle in the sky - constantly improving conditions for planting and growing lifeforms.

Either space engineers is such a long term endeavor and I am being impatient, or I am wavering in ability focus and commit.

Now this update every two weeks will be permanent and carry more weight, forcing me to dedicate more consideration to its position amidst my comment history "story".
Enforcing locking with C++ nonmovable types
There are tons of reasons this wouldn’t have happened. Lots of this is speculation but:

Seems likely this is a gradient, not a binary thing, so perhaps someone with a beneficial mutation would just live a little longer. There’s not a ton of evolutionary pressure at the old age side of the spectrum, you’re not reproducing a lot, so it may not get picked up.

Wilder speculation: it could be that indeed this has been happening and is why humans live about 2x as long as chimps and gorillas.

Personally I think it’s quite unlikely that in humans single genes would have large deltas on age. There are maybe a few hints from supercentenarians (https://en.wikipedia.org/wiki/Research_into_centenarians) that telomerase and other genes have some effect, but the “one gene for aging” in humans is elusive. As a result, it’s hard to predict how all this would play out evolutionarily.
I put new facts into Anki ( https://apps.ankiweb.net/ ) and then they get reviewed daily, with a steady, slow addition of new facts.

It's a very effective way to keep everything in long-term memory. (It's also very difficult. You're trying to recall items that are just at the edge of your memory.)
We don’t know it’s zero. What fraction of humans who have ever lived have died of old age?

We could have age-proof people living among us today who happen to die in car accidents or any number of other causes.
https://en.wikipedia.org/wiki/Positive_and_negative_predicti...

If the number of true positives is 10/1000, and the test gives you 11/1000 positive results, then 1/11 of your tested positive results are false positives. (Actually closer to 9% than 10%).
Because with a false positive antibody test then you can still contract and be a carrier. This is a problem for the immunity passport proposals (which I think are a terrible idea anyway, but that’s beside the point)
Are There Problems That Computers Can't Solve?
I'm not taking a stance on the topic, but I think that if you quote the part that you did, then you should also quote the part right before it, for full context:

> In the race to effect substantial, system-wide rejuvenation, Harold Katcher is a dark horse. He has the right academic credentials and a solid history of research. In fact, in earlier life he was part of a team that discovered the breast cancer gene, brca1. I asked Harold for a biographical sketch, and have printed it in a box at the end of this posting.

And here's the bio sketch itself:

> So, you might consider me a late bloomer. While I have thousands of citations in the literature, with publications ranging from the discovery of the human ‘breast cancer gene’, to protein structure, bacteriology, biotechnology, bioinformatics, and biochemistry, there was no center or direction to my work as I had given up my personal goal of solving/curing aging when I learned that ‘wear and tear’ was the cause of it. Yet something happened in year 1985 when I was in California working with Michael Waterman and Temple Smith (fathers of bioinformatics) that is inexplicable: I found myself in Intensive Care with a tube inserted into my trachea and the knowledge that I might not live. And then I had a dream: I dreamed that somehow in the far future (and on another world), I was being feted for ‘bringing immortality to mankind’. Clearly, I survived that incident (started with an infected tooth). I lived a wonderful life – becoming a computer programmer (which I loved), leaving that for the University of Maryland’s Asian division, becoming a full professor and then the Academic Director for the Sciences, in Tokyo, Japan. By the time I left Japan in 2004, (my daughter Sasha was a fourth-grader, (yonensei), in the Japanese school system), I was teaching for U of M online – somewhat retired, and looking forwards to writing computer programs for fun and profit. Yet I never ever forgot that dream. It was clearly impossible; I had no lab – and really, there was no way to repair all damaged cells – it’d be like sweeping back the ocean. And then, in 2009, I read an old paper from 2005, a paper written by the Conboys, (Michael and Irina), Tom Rando and others, coming from Irv Weisman’s lab, that completely changed my life; that showed me that everything I believed about aging was wrong – that aging occurred at the organismic level, not at the cellular level and could be reversed. Well, the rest of the story is about persistence and the blessed intervention of Akshay Sanghvi who too saw there was another way and provided the structural, monetary, and emotional support (and some good ideas) that had me start a new career at age 72 in Mumbai, India. I feel twenty years younger than I did three years ago, I guess that’s another hint about aging. Now the ‘mystical’ dream? It wouldn’t be the first time in history that that happened – take that as a datum.
Why Is Nintendo Switch in High Demand, Should You Get One
Different reasons for different people. Some combination of:

* It's better than the alternative, and it can be made to work, since once I140 is approved you can renew H1 indefinitely (unless sth goes wrong, like right now, but that's a risk that doesn't look so big initially when all is still well).

* The wait only became this bad around 2008 or so. At the time, nobody knew there wouldn't be a realistic chance to get to gc. A lot of people have been in the system since that time.

* It doesn't always start with wanting to move to the US permanently. You go to a US college, or move for a job in the US (maybe the company you've already been part of offered it, maybe not), thinking it'd temporary. Then you build a life, make friendships, and realize you want to stay.

* Or maybe your parents moved when you are a kid and the US is all you know. But when you turn 18, it's F1/OPT/H1 or go to a foreign country (that you happen to be a citizen of, but have no real relationship with).

Above are all real examples I personally know.

Also, while for non-Indian immigrants it is at least possible to get a gc eventually, this is also by no means certain. Very stressful as well.
> 80 is probably the sustainable maximum for any normal human.

Not according to research. I know that academia features long hours. I never heard of academia as an example of efficiency through. Game industry is another hours high occupation (and the studies about crunch are from there).

Also, having kids after 40 is not exactly advisable for women. You are getting into risk category health vise.

People who work 80 hours a week and have children simply have spouse who does all childcare related work and career sacrifice (if they had career).
That was a joke by the CEO.

However, they have investigated (and I believe are still investigating) whether it would be possible to have a standing plane.

To be honest, for the Dublin to London route it wouldn't be too bad.