skysight-inc/HackerNews huggingface dataset:
This laptop is supposed to be an upgradeable machine for hacking. Why can't I upgrade the RAM? 4 GB is not a lot these days.
The laziness of believing that we are going to have a rejuvenation pill in the future is a big scam/joke. Just like pills to recover from baldness. Most people are running on 10, 20% of their full healthy, no pills are never going to change that. Not even a weight reduction pill will help the ones who wants to still be able to eat junk food and drink soda.
I wonder if this concept really sticks...

I worked for a company that was acquired that was based in Minnesota. The acquiring company absolutely could not find warm bodies in the bay area to do ... tech support. So they finally asked if the bumpkins in Minnesota could help out.

I traveled out there and everyone was very nice but I had things explained to me like I hadn't used a computer before, or couldn't follow a simple process. One of the directors asked me "What do people in Minnesota do for work?" I told him "Same as around here.", he found that hard to believe and told me about how is team were all high performers in college with fancy degrees and such.

Anyway a month later my team is out performing the valley team with higher customer service scores (funny that if you actually call your customers they like it, you can solve problems faster...) and so on. All with a smaller team and at ~2/3rds the price (possibly less).

I mean it was just tech support, on some fairly high end equipment. But still it was not rocket science.

A few years later to save costs ... they skip Minnesota try disastrously to offshore to India.

Then after the company is acquired again they take the opportunity to axe everyone in MN, and again ... can't find anyone to work in the bay...

I just don't know, these choices seem sort of institutionalized / culture oriented.
Personally for me, I always second guess the architecture/approach of my personal projects. That's usually my biggest struggle! hahaha, weird as it may sound. Not the easiest 'internal' issue to overcome, because I don't know what I don't know. So I figured that just going deep into a particular domain will be helpful.

When it comes to deployment, I personally have quite a deep experience working with Kubernetes and docker at work. Not the easiest to learn, but definitely rewarding when you can get it right, I'm sure you have similar experiences as well! Would love to hear from you what are your personal projects as well (:

Here's just my attempt to learn and address my 'don't know what I don't know' issue:
https://blog.phuaxueyong.com/post/2020-05-03-3-more-cloud-de...
Why does this article talk about bacteria?

I don't see any mention of bacteria in the original article https://www.nature.com/articles/s41586-020-2199-7
Instead, if I understand it correctly, it seems to say that it's certain intestinal cells (not bacteria) that sense sugar. Do I misunderstand, or is the news article wrong?
I wonder if HN would have a viscerally negative knee jerk reaction if this was about a cancer treatment breakthrough, that could have saved someone they know or love if it was discovered in due time.

This whole “fuck the billionaires” attitude on a website that is supposed to uphold some kind of techno-progressiveness is just so tiresome.

We get it, you don’t like people with money and you consider them vampires because they want to avoid dying for as long as possible.

Go and be insufferable elsewhere.
For a simple static site, is this a better option than Gatsby?
I suggest regular 4-day weekends in which you silence work notifications completely.
We'd have PHP in the browser.
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this case) endogenously produced the signalling molecules which Katcher is proposing as treatment? In the case of this proposal this sort of objection is particularly strong, since (though the blog post is silent as to what the treatment is) it's given that they are fractions from blood, so they're substances which the body produces in some quantity anyway, and which are sufficiently non-dose-specific that Katcher, with limited resources, could devise a reasonably effective regimen.

Parabiosis is one of the most striking (and just weird) phenomena in aging research, so efforts to understand what's going on with it are liable to bear interesting fruit. I'm just pointing out that there's good reason to doubt that this particular "breakthrough" is the "cure."
I actually think hey are too sour most of the time. That's one of the reasons I don't like eating fruits much.
There are some animals that don't "age" like we do. These animals can live indefinitely, until they are eaten or die in some accidental way.

Aging is a set of complex bio-physical-chemical processes. We have actually made a lot of progress in recent decades understanding how this happens. There is no fundamental reason we won't be able to better understand these processes and then mitigate them heavily, if not entirely.

Aubrey de Grey is one of the scientists leading these efforts and his work, along with others, is very interesting. It seems to me there is real potential here. There are many difficult hurdles, but I find it plausible we might overcome them to an extent where it is possible to significantly extend the human lifespan.

If course, if this actually happens, there will be massive social, political, and economic consequences. I'm not exactly sure how that would play out. I'm a bit of an optimist, so I imagine there would be some sort of new non-dystopic paradigm that arises.
This is a very good point. There seem to be a non-trivial number of dyslexic engineers out there (I've worked with at least 3-4 over my career), and they struggle a lot to write - although they'll hide it out of cultural taboo. They tend to have excellent verbal communication skills though and seem to handle coding perfectly fine - one of them being one of the best engineers/mathematicians I've worked with. I wonder how we can better accommodate it, especially in a remote environment.
Mostly I enjoy working on most stuff when there are no blockers. So I work on minimizing blockers so I am not getting interrupted by stuff I could have avoided.
If we want to ensure that the active population is always above herd immunity threshold, 10% or 20% false positives would be acceptable, since the population in contact would still be 80 or 90% immune.
Yes, it does.

The hypothesis is that "clock molecules" in the bloodstream provide a global age-clock for about five other tissue-specific age-clocks in the body. Spoofing the global clock signal for a long enough period tricks the subsystem clocks into thinking they are younger than they really are, including the native global age-clock mechanism.

Completely replacing your own blood with a young person's blood, repeating if necessary, would also accomplish the same trick, more expensively.

The real question is whether old tissues can function like young tissues when tricked into trying.
Because a significant portion does not imply that majority of the population will exercise prudence.
Single family homes? Or condos?
I didn't see anything about firmware. Does this have an intel-management-engine-like firmware-backdoor or not?
I still miss Hydrox cookies.
My $0.02, this was mostly due to historical lagging a more out-of-the-box 'complete' solution like JSX/React, specifically in:

(1) Poor native browser support until recently, Firefox originally refused to support Web Components v0 at all (now called Custom Elements in v1, they are supported in all evergreen browsers mostly).

(1a) Available polyfills were initially buggy and had severe performance issues on older browsers.

(2) Lack of proper templating, though I personally quite adore template literals and approaches like e.g. `lit-html`.

(3) Lack of robust styling API - custom styles felt coarse and tacked on in v0 especially, and were poorly supported by pre-processors like LESS/SASS.

(4) Lots of impedance mismatch issues connecting standard JS/HTML/CSS libraries with the Shadow DOM.
It seems ok now that I'm trying it, but I definitely remember not being able to find a specific settings screen (I think it was network connections) even when typing its literal exact name. Same for various applications. Maybe they fixed it in one of the more recent Windows 10 updates.
It’s falling with “Network Error” instantly for me. I’m assuming we’ve collectively embraced it to death.
I saw this talk live at Strange Loop 2013, and I'm going to be a contrarian: I wasn't impressed. I don't mean to bash Chuck Moore. Forth is cool, and this chip looks neat, but my impression is that this is a solution looking for a problem. Chuck Moore is having a lot of fun working on it, but he fails to convey why this is useful.

The impression that I had is that the whole talk was Chuck Moore going "look at all the cool assembler tricks I can do!". At no point did he ever demonstrate how his chip could be used to solve anything resembling a real-world use case. Instead, what he demonstrated was that his architecture was very esoteric and impractical to use. Some time could have been spent explaining how this chip can do some common computation (matrix multiplication, image processing, anything) more efficiently than an ARM chip or something we're already familiar with.

He didn't really provide any benchmarks of anything, be it performance or power consumption, and my understanding was that, at the time the talk was given, based on the Q&A session, that he had no customers buying said chips (I wonder why?).
Cool! I was looking for something like this but couldn't find it. Oh well, building my own kept me sane during lockdown.

I think combinator libraries like this and one I'm building are definitely better than templating languages, although JSX can also work really well, in particular because it retains the HTML syntax making it easy to copy from the browser into code.
Started documenting the things I learn in a section of my website called "snippets". It's purpose is to be a registry of copy-paste resources, like a personal stack overflow, and I'm trying to keep it as small and short as possible. Also I don't write things there right away. First they go in a "backlog" in my notes, and once I require the knowledge but forget the details I transition it into a post on the website. This forces me to still remember stuff and helps keep only the relevant pieces around. Still very new to this approach, only time will tell if it's indeed worth the effort.
awesome post! Thank you. I can see huge white space in non-IT use cases.
Which is the stack you usually use to start your side projects?
I've been thinking about starting a project on my own for a long time and I was wondering which stack is usually used.

I've been developing micro service applications for a long time and the best option I can think of is to use the MERN stack.

What is the best option for you?
The "object" syntax reminds me a lot of Clojure/script's Hiccup (https://github.com/weavejester/hiccup) style, which has become a de-facto standard across many popular libraries. In hiccup, this example:

{
tag: "button",
attributes: {
"id": "baz",
"class": "foo bar",
"data": "1",
"onclick": f,
},
children: [
"Hello",
{
tag: "em",
attributes: {},
children: ["there"],
}
]
}

Would be represented as:

[:button#baz.foo.bar {:data 1 :on-click f} "Hello" [:em "there"]]
Are there different Oeros? What you described doesn't seem to fit the description of a the North American Oreo. It's artificial sweetened shortening wedged between two chocolaty "wafers". No powdery sugar involved.
Show HN: Building your own Router with a Raspberry Pi
Among other notions, Lingua ex Machina [1] discussed possible evolutionary pathways which allowed complex language (nestable subject verb object clauses) to arise from simple language (just verb object statements).

I found that book on a lark and barely understood the content. I was tinkering with knowledge representation and semantic web stuff at the time. The utility of subject verb object clauses stuck with me and seems to come up frequently.

I'd love some ELI5's for how this paper advances our understanding.

[1] Lingua Ex Machina: Reconciling Darwin and Chomsky with the Human Brain [2001]
https://www.goodreads.com/book/show/252045.Lingua_Ex_Machina
Definitely, compared to Gatsby, Next is much simpler. At least every time I tried Gatsby, I just had to give up after a few hours because of the complexity and massive amount of boiler plate that you had to stitch up yourself from examples.
thanks. any particular meditation technique you recommend ?
Bitcoin Halving for Dummies
The Bitcoin Halving explained and what all the fuss is about.
AMC's stock soars after report Amazon held merger talks
In the US, they're $119 through Quest Diagnostics. In some areas and with some insurance companies, that cost is fully covered.
Every couple of months or so, I guess.
And importantly non-stop flights to more than a handful of destinations from those airports. Living near a major airport rather than a small regional airport can significantly cut the total travel time and cost even with the added inconveniences of large airports.
>You can frequently determine the balance of power between any two people in an organization by seeing which one has to read and prepare organized documents and presentations, and which one can simply speak and be spoken to. People want to paint pictures of themselves as being able to synthesize knowledge and ideas instantly, utter commands in real time and see them turned into action. In the other direction, they have no time for reading - you must request an audience with them and survive their real-time verbal sparring and probing questions to have your ideas received and considered.

What if I'm just bad with the async nature of slack and/or email? If I had a nickel for everytime a long drawn out back and forth email thread that was resolved in less than two minutes with a face to face conversion and a white board I would have a shit load of nickels.
People who had this mutation could have died of causes other than aging.
Luck is not success.
You dismiss the challenges of finding a single recipe by mentioning you find several and combine them? That completely defeats the purpose of a recipe. You're literally creating your own recipe at that stage.
I'm not really plugged in to the industry. I've used it with bazel cc_binary targets, so I know it works.
Isn't that the way that every single organism ever has lived?
As a windows user and primarily Android users, when I bought an ipad a few months ago I was stunned at the things that were either unintuitive or impossible to do in ipad (I just want an alphabetical list of all the apps installed. Is that so hard? Why is it is still so hard to go back one space in a text field?)

Looking at the new ipad pro keyboard monstrosity, I can't imagine how people wouldn't laugh it out of the room if microsoft, google, or samsung released the same product. Doubles the weight of the tablet and has that weird hinge thing, and that price.
I don’t see how your first sentence is supported by the rest of them.
Nice downvotes, found the sycophant Airbnb managers who just fired everyone :)
What's wrong with 10% of them being false positives? (also I think it's 9%)
Show HN: A home for Figma frames and product teams to collaborate
My understanding is the Big Bang and the origin of the universe are two different things.

Perhaps focusing a telescope on redshift or detecting sensitive electromagnetic radiation has equivalence of heating something up and squeezing everything together.

The Big Bang is something that occurred for sure.

Maybe it still occurs, or only occurs when we do something, like negative pressure in regards to thermal radiation.

Heat transfers with nothing in between, no conductive surfaces or convective medium. The overhead of "what already exists" speeds up and slows down clocks to transfer heat, abstracted away in photons and photoelectrics, discovered over a hundred years ago.

With spectroscopy, fields take away the question of emission from atom building blocks or a reaction from the medium. That's a hundred years old too.

Gravity to this century is supposed to be what electromagnetism was to the last century. Plenty of theory for it. It just takes years of study to communicate it.

Often the answer to "that's funny ... I wonder why?" is "Insignificant, back to professional work."

Applications exist too. Probably will first start seeing it in medicine, quantum biology, cellular mitosis and neurological applications, such as therapeutic medical imaging.

I wonder what matter waves in Earth or solar orbit applied to Bell's theorem would do? Spontaneous generation inside of their orbit? Would that risk be palatable?
the surface pro 2 was released seven years ago. whatever your experience was then, it isn't relevant now. the surface pro line has undergone big design changes and improvements since then.
Byzantine Generals Problem [pdf]
H1B's already need to exceed the prevailing wage, as determined by DoL.

You can argue about where they actually end up, but it's not the bottom 20%. Esp once you figure in immigration related overheads (that's staff, not just fees and travel).

Higher salaries for H1B's would require the right to change jobs easily, unlike now where there's a tremendous risk. And then there's L1's, who have no negotiation power at all.
The specific vehicle we'd be getting is a PHEV Pacifica. The pricing can actually come in lower than the equivalent non-hyrbid version depending on the exact incentives in play.

Our primary use case is moving kids and groceries, all of which is less than 30 miles round trip. On the highway it still gets ~10mpg better than the gas version.
Vacation rentals still have demand. Many people would rather spend the lockdown in a nice house in nature somewhere than in their urban place. The problem is that at least in the US many states issues a ban on non-essential rentals, so they are illegal currently in many places. Once that's lifted many of these places would be fully booked. The rental places in urban areas that rely on tourists visiting cities are a different story.
And, the real farce is that Google mistakenly sees all that scrolling up and down the page, looking for the recipe as 'engagement' and "Dwell time".
Coronavirus: Wuhan in first virus cluster since end of lockdown
The NHSX tracing app source code was released but privacy fears remain
At risk of sounding absolutely insane:

There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of:

1. being burned at the stake

2. being trialed in repeated experiments

3. being deified, and then subsequently being burned at the stake.

---

I realize my comment sounds like a joke, but I'm entirely serious. If you or I found out we're not aging normally and look e.g. 25 by the time we reach 40, or 30 by the time we reach 45, would either of us remain in our current lives?
i feel less like a dummy now. appreciated this simple explanation a lot! :)
I live in Boston and drive every day still. This is anecdotal - but I've seen the same amount of bad driving as ever (largely around merging, roundabouts, and turn signal usage) but now it's at a significantly higher speed because on I-95 and I-93 you can easily hit 85 mph instead of the customary 45 mph the whole way during rush hour.

I don't have any data, but I imagine that explains the similar serious accident rate.
Here is how i use it

1. netflix\youtube

2. outlook\office - perfect for writing emails and reviewing docs when out of the office

3. remoting into a more powerful computer - I RDC into my desktop at home or work if I need to run an ide or do any other heavy lifting

(i got the model with 8gb ram and the faster processor)
There’s a host of evidence that parabiosis (blood transfer from young to old) works well in mice/rats for a variety of aging issues. Some of the more concrete claims that it will transfer to humans are not as well supported to my knowledge, but that doesn’t mean impossible, just not known yet. I would also question some of the strong claims about the hypothalamus as a centrally controlled aging clock, and that DNA methylation is a driver (rather than a marker) of aging. These are big claims, the article supports them poorly. DNA methylation is an on/off signal for genes in the cell and is a subject of active research. As you can imagine it’s been implicated in a large number of biological processes including cancer. I’d be careful messing around with it in a global way.

I know of one at least one company (Spring Discovery) that is following some of this work up to find some driver molecules that could have the same effect as parabiosis. If interested in the topic I’d look at the work from the labs mentioned in the article as well as Saul Villeda (former grad student of Wyss-Coray, full disclosure I know him socially) at UCSF.

TLDR: This article is a breathless take on active research, clearly the author is excited. There’s reason to keep investigating, but the conclusions in the article are stronger than what the research can say conclusively at the moment. Very early days.
Experience end-to-end data science without coding
Keep hoping. Homeownership rates are very high in Republican country and the government will do almost anything to prop up home prices. Of course if they can find a policy that hurts the coastal homeowners while protecting the yeehaw homeowners they will but expect lots of money printing.
I sometimes have trouble even with beats/pulsing - that can break my concentration at times. I use non-vocal jazz or electronica stuff, but mask with brown/grey noise on top, and that seems to be the best mix, but I find when beats are too noticeable... I notice them.
Do you have any data supporting this? I'd like to think I could be an accurate judge of this myself, but given that my consumption of media is extremely biased by my location and languages of literacy, I don't think my anecdotal data is worth anything.
I've always thought of copyrighted music as "sound recipes"
"Tom Clancy's Rainbow Six Siege"
40,000 Triangles + 3 2048 x 2048 Texture Maps
https://www.artstation.com/artwork/0eKg8

"Fortnite"
LOD 0: 23,041 Triangles
https://i.imgur.com/y8fOip0.png

I'll give you that purely GPU-skinned on PS4 can go up to 700k for the entire scene, but that means 14 or less people visible at a 50k budget.

So for a game like Assassin's Creed, the per-character and per-item poly counts need to be significantly lower, to make sure the combined sum of the scene is still manageable.
If the reported immune rate is 80%, with 10-20% false positives, wouldn't the real immunity rate be 64-72%?
One of the main barriers to writing things down in organizations is the knowledge that anything written down can be subpoenaed. At least in the US, management of legal liability is a major part of running most organizations.
Maybe not: the only way we're actually going to realistically colonize space as a species is if people live so long that a few hundred years in a spaceship is a reasonable sacrifice. I would imagine that the same people who were willing to spend fortunes on rejuvenation would also be willing to spend fortunes exploring new galaxies.
Vroom Files Confidentially for IPO
Evolution may not select for long life?

https://biology.stackexchange.com/questions/17077/why-does-e...
You‘d have to assume that they are only read during SSG/SSR.
I have nothing but good things to say about Next.js, one of the few web libraries that I'm really excited about. Great developer experience, the API is simple and very stable and the feature set is really powerful.
You can also take a look at mithril.js implementation of hyperscript [0]

[0] https://github.com/MithrilJS/mithril.js/blob/next/render/hyperscript.js