skysight-inc/HackerNews huggingface dataset:
There is data showing that flu vaccination reduces the chance of heart attack. The effect is about as strong as giving up smoking.
Preaching to the choir. I guess what I mean is that as a small island state far from anywhere else, if it gets bad, it gets _much worse_ than on the mainland.
There is no evidence whatsoever that the harmful effects of nicotine cause even 1% of the damage caused by the harmful effects of inhaling combustion byproducts. This is irrelevant, and is just emotional spillover from the decades of repetition of how bad smoking is.

(In some ways it’s like people trying to ban rifles that cause ~700 deaths per year in the US while small caliber handguns cause >11k.)

Salty fried foods are a bigger public health issue right now than if every nonsmoker took up vaping.
I shouldn't assume school districts care

voted +1 touché
What are the actual impacts of nicotine on the body? I thought most of the harm came from the other carcinogens in cigarettes and tobacco rather than nicotine itself
Herding people into open office spaces has already been proven to hurt productivity.
I'm sorry for it. Just wondering and want to know your perspective, if teams like ML and Data Science are more of a luxury than a necessity? They're mostly not a revenue generating team and I constantly see them being part of such layoffs.
Look at how much energy and computer cycles they have to put into just for folding a single protein and then realise that scaling it up at our current level is basically impossible: https://foldingathome.org/
If you are using WebRTC with a centralized SFU, you do not have e2e encryption. If agora is a centralized server for WebRTC multiplexing, please correct your documentation. You are not able to do e2e encryption in the browser using a centralized SFU: it literally does not exist (yet.)
I looked at more prompts. I think the three I checked out at random must have been an unlucky sample because most of the ones I looked at just now have had much more intention and clarity of purpose. I suspect you're getting this feedback now and not earlier because you happened to post it on HN at the same time as having an outlier prompt. Congrats on the site! It's really awesome.
NVIDIA has already communicated to many of their employees that they will be expected to return to the office once they are legally permitted to do so.
That's the problem, in a nutshell.

In order to quit, you need to train your body to want less nicotine, since that is the addictive part. Juul delivers the same or more nicotine as a cigarette. It is not intended to be a product to help smokers quit smoking.
I used SmartClient when it was launched in 2002 and that did client-side rendering back then: https://en.wikipedia.org/wiki/SmartClient - I've recently taken the JS version (not GWT) and ported it to a set of ES6 classes and modules.

I used to work for a portal vendor called Plumtree in 2004 (later acquired by BEA and then Oracle) and much of their stuff did client-side rendering.

The idea of making web interfaces more declarative and less tied to DOM manipulation has been evolving since then. Many developers I'd encounter back in those days moaned that we were not using jQuery or MooTools or whatever.

React is very nice - don't get me wrong - but its popularity has much to do with the mindset of developers shifting away from seeing JavaScript as a way of 'adding spruce' to 'web pages'.
I disagree. Epidemiology is a science that generates facts and modelling with various degrees of accuracy. What you do with the science is in the realm of public policy and politics
You can easily patch the state revenue holes without fixing the pension obligations. You basically give the states the difference between what they were projecting and what the reality is. By doing this, you fix part of the economy keeping up employment until the private sector can come back online. If you let states fall down right now you are going to turn this into a depression. It just means the beginning of Lyft’s troubles.

There is nothing to applaud with his actions or statements. It’s just malicious and gives the rest of the world a chance to out compete America.
I've read a few references that mention taking vitamin K2 together with the Vitamin D makes this a non issue. I don't have a link handy, though.
> Do you know how efficient the system was before HFT started up? And, do you know how many people were working in trading before, and how many are, for a similar fraction of stock volume?

Again this weirdly mixes HFT with electronic automated trading, which I really don't think anyone in the domain would readily mix.

HFT by arbing over latency is entirely different to the automation of boring trader tasks that see less people employed to do the same thing in the front office.

I can't continue this more, it's just blind allegiance from people who are clearly not in the domain.

HFT != electronic trading
If you're still interested you might want to ask on TUHS: https://minnie.tuhs.org/pipermail/tuhs/
>If a company states in their investor quarterly report that they had 1M active users, they better be able to prove it in an audit.

Is this even legal? I've never heard of a company letting an outside firm go through their database to confirm any sort of statistic like that. Who is doing this auditing?
It's one thing to "restructure" the comp package for future employees, and something else to change compensation arrangements retroactively after your employers have upheld their end of the deal.
I agree (I think). Personally I believe the two are related. Epidemiology must inform the policy. And similarly we can only understand epidemiology if we understand the basic building blocks of immunity.

That, in fact, is why I have an initial section that's just about these deceptively simple concepts that we all need to understand. I wish our leaders had actually metaphorically sat the American people down and explained the basics. The average person really does not know what a virus is, or how diseases are transmitted.

So, I actually entirely agree with the position that this is something that relates to epidemiology. Where I differ is that I don't believe in gatekeeping, I think if someone has taken the effort to synthesize research into a policy proposal, however poorly, it seems at least worth debating the ideas on their merits. The experts who know more than me (and they do, at least some of them) should be able to convince a rational/reasonable person that their position is the correct one without resorting to credential-waving.

--

BTW I do read quite a lot of research papers, but I don't naturally have much interest in epidemiology. Just to give you an idea, I usually end up reading papers about stuff like: moist wound healing, and the role of red light therapy in fibroblast differentiation, and more broadly the role of electromagnetism in wound healing and neuronal galvanotropism. Weird stuff like that that's connected by invisible threads.

So, why did I read a bunch of epidemiology/COVID-related research papers? Well, the state of discourse here in the US, and also globally, has hit such a level of insanity that I decided that I needed to figure out what the facts were. (I'm not saying I have "figured out the facts" perfectly, or even at all, just that I am trying to) Honestly, it might sound ridiculous, but the turning point for me was reading that Venice Skate park was filled in with sand to prevent people from skating there. That is what informed my intuition that we are collectively being driven by superstition, and therefore what motivated me to read a bunch of research papers and reach my own conclusion about what's going on.

My ultimate conclusion? Well, the writeup is pretty clear on that one.
Do you have a source for that first paragraph?

My understanding is that viruses don't have replication machinery at all - it's one of the defining features of viruses. Their host cells are essentially tricked into producing copies of the virus.
Yes, but they're workers. People generally retire at 65, and in the MTA, I believe you can get a full pension at 55. The population that pushes up the mortality numbers are 70+, and they're not driving a bus or a train anymore.
Cigarette smoking among schoolchildren was already on a heavy downward trend for decades until Juul made it "cool" again. In fact there has been a slight increase in recent years, as teenagers start with Juul and then take up cigarettes.

They have helped a ton of adults quit or reduce smoking, which is great, but they have also explicitly targeted kids via presentations in classrooms, paid underage Instagram influencers and lots more. There is no requirement to excuse the second because of the first.
Not having thousands of people dying would be nice too. Hopefully you're not this tone deaf in real life too.
Yes, that, too. I was thinking of this, but I think they're all closely related. And hey, even if the science doesn't pan out, you've still probably helped someone out with your donation.

https://www.nature.com/articles/d42473-018-00382-9
>And for the sake of us all, i hope that if the case were to be brought in front of SCOTUS, they'd correctly write that

And you would be wrong, as this is the quintessential "shouting fire in a crowded theater" analogy. Free Speech is conditional, since at least 1969 when it last went to the SCOTUS. The reason it's unproductive to start from that space, is because today, the Constitution does not grant you unconditional rights. You don't have an unconditional right to own a gun either.
PSA: You cannot use %.*s to print strings with NUL bytes
Following does not do what most people would expect:

+$ cat main.c
#include <stdio.h>

int main(void) {
char str[] = { 0, 'a' };
printf("`%.*s'\n", sizeof(str), str);
return 0;
}
+$ gcc -o main main.c
+$ ./main
`'

This post was triggered by seeing comment suggesting just this (and I can't
reply since it is too old). But people should be warned.
>Every libertarian I know

then you do not know any libertarians, or you have massively overstated their acceptance of these measures.

Having vested power in a single person to literally close the entirety of the economy, and arrest people for exercising basic rights is a violation of all things that should America Stands for. No libertarian would stand for arresting people out for a walk, threatening to arrest people for posting on Instagram, arresting people enjoying activity outside alone in ocean, arresting people if they sit in chair on the beach, but sitting in the same spot in the sand is ok, etc etc etc...

While some libertarians may accept the basic social distancing orders, even closing some events and gather thing, there is a mile long list of massive government overreach in every region and state including CA.

Everyone likes to hold America and other First world nations as "free" in contrast to Authoritarian States like China, but the line gets less defined every year, and every crisis

I am sure I will get zero support for my thoughts here, but if rights end when a crisis begins we have no rights at all. Today it is a pandemic that they have used to justify their authoritarian action, What will it be next, and how far will they push their power after seeing how well fear will enable them to cease control.

Too many people during this time are shortsighted, failing to see the bigger threat to liberty this precedent will bring.
Was it intentional that you left out the parts of the article that show blue states pay more in, and receive less per resident relative to what they paid in? Because you completely misrepresented what is claimed by only highlighting the outlay per resident
Thank you. https://gitlab.com/ryankemper/writings/-/commit/ca2771bbe1df...
If they were thinking about retiring already; at 20 years, that's an extra half a year of salary than yesterday. This offer is in addition to retirement plans they already have (401k and pension)
Potentially. What would be the harm in further regulation? I feel there is no benefit to a lack of regulation. But that's just my opinion. If my legislators were to ask me if I thought we should have more regulation on nicotine advertisement, I would say yes. Which is what we have legislators for.
Both Powell's and Nelder-mead are often the only thing I can get to work when the optimization is of a quantity derived from integrating a system of differential equations. Not sure why that is.
I’m confused. This looks like soccer, yet none of the players are flopping and pretending to be injured.
when it's ready, of course.

It just started passing packets (ping) last week. It would have been at this point weeks ago, had Jason not baked his e-mail address into the handshake protocol. (Harumph.)
> Interesting thing... Vitamin D is one of those things that, when vitamins come up on HN, you will often hear the refrain that "it's the one vitamin that large numbers of people are actually deficient in and ought to supplement."

Well, let me add to the narrative, as this was the concentration of my Undergrad studies. Vitamin D, and its analogues are not actually vitamins, they're steroid-hormones and behave as such; look at its molecular structure [1] and its synthesis in the presence of UV light (as this actually how you should be acquiring it).

Most people are deficient in Vitmanin D, the recommended dose of 600 IU are actually not sufficient as many studies, research lends credence to as those that induced viable therapies were often upwards of 4000-10000 IU. The IOM is to blame for this, and a heated debate amongst researchers.

I won't go into full detail on that, but Vitamin D is a critical precursor and reactant in many vital metabolic reactions, my personal concentration was in inducing apoptosis in certain cancer cells with calcitriol, EB 1089, CB 1093, and p53. My proposals were rejected for Independent Studies and I never undertook it in the lab, unfortunately.

> Unfortunately the daily recommended value was established erroneously and should be much higher. Many research papers mention this...

Exactly. My bible was a Vitamin D book with 100+ chapters detailing researchers that published papers detailing how their models were showing that such low IU of Vitmain D were insufficient, going against the IOM's RDL.

If any of you are so inclined the 2nd Volume of Vitamin D by Feldman has been released [2], its expensive but still way less than what the last copies of vol 1 were that I paid back then.

> Nobody makes any money if it turns out to be a good treatment, so nobody will fund the research

You have no idea the amount of dismay I felt when I realized this was the case when I was in school; though I would argue they've fund(ed) it in the past, the problem is their is no way to place IP on Vitamin D itself and therefore Big Pharma's business model doesn't apply, so it can show favourable results but it will be killed because their is nothing to bring to Market as an exclusive seller like they do for drugs. Many therapies could have been explored since H1N1, 2009, but it falls on deaf ears and it takes pandemics like these to shake people into delving into Public Health more seriously.

I hope changes are made by motivated students and researchers, ideally outside of Universities because I know I no longer have the patience or drive to try any more.

1: https://external-content.duckduckgo.com/iu/?u=https%3A%2F%2F...

2: https://www.amazon.com/Vitamin-Disease-Therapeutics-David-Fe...
I should have explained more here. This was only for family communication. Other communication is split up pretty much depending on where the friend is. Convincing people to up and shift is easier said than done. It could be argued it might be better that way because then my data isn't all with one message service.

For other communications I use Rocket.Chat for team collab, signal, keybase chat or sms(which if they do happen to have iMessage does convert). I definitely do not trust facebook any more than Google. And I would agree thats a sideways move not an improvement
Yes and they scale that way by ignoring safety regulations.
In the years leading up to the Civil War, the states often passed bills specifically intended to hurt each other, and the Federal government passed laws intended to economically harm the south. It was a complete shitshow.

Today's politics are positively gentrified by comparison.
Trump is the head of the government, but he is not the government. The US government is such a behemoth not even he can stop it doing what it does. Too many vested interests in Boeing to let it fail.
What about this seems wrong or strange? That seems completely and utterly reasonable to me.
Jesus said so in the Bible.
It's great to see new football strategies. But I agree, personally I'm most excited about proving/discovering new math theorems using ML.
That's cartoonishly exploitative. Juul should be fined for this predatory marketing.
This opinion requires a great deal of justification.
> Now it comes time for due, we don't want to fund these anymore.

The people who agreed to this never wanted to fund them in the first place. If they had, they would have increased taxes or reduced benefits. Instead, we are seeing guaranteed 3% pension increases annually when inflation is <2% and rosy projections about 8% stock market returns when in practice it's more like 5%.
I'm yet to do micro-services at all at work or outside. I count myself lucky :-).
The thing I dislike about all these maxims is exactly what happened here. You took this:

"Then, don't stop, keep searching until you find a better one."

and turned it into:

"then search a bit more."

There was no mention of "unbounded search time" in the original maxim, and the person that you're responding to is following the maxim exactly ("don't stop until you find a better one").

Don't get me wrong - I think your interpretation is reasonable and a better idea than the original. But everyone takes these maxims and adds layers of interpretation and good sense to such a degree that you may as well have just trusted in your good sense to begin with.

If the original maxim had been more actionable ("then spend no more than 20% of the time you originally spend searching to attempt to find a better one, stopping if you do so") it might be more helpful, but it loses that air of folksy wisdom that these maxims love to put on.
Depends on a dog, some beagles won't shut up if you speak with them.
I have no issue with UI benefits, or equivalents thereof. I have no issue with the current extension of UI benefits.

But I do have issue with the claim that we could never hire enough contact tracers...

1. In the middle of a massive surge of unemployment.

2. When we are already paying millions of people to... Sit around, and do nothing.

The need for workers exists, the money to pay them exists, the workers exist, and some of them actually want to work. Why can't we put those four things together?
Hmm. I’d be curious to get your take on the lancet link. Are they just referencing different sources or does one have newer information?

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...
Why would that be a problem? The salary & pension are compensation for the career of labor. No part of the pension that person _earned_ is owed back to the original state. That doesn’t make any sense.
Hah I did a similar thing a few days ago using their 6" paper display. https://blog.brixit.nl/epaper/

I chose to use the usb interface since had a server running to attach it to already
Just because you've not seen something doesn't mean its not happened. The sad reality is that people all over the world have lived like this forever. Warzones, undeveloped countries, etc.

Afghanistan hasn't been safe or stable enough for literally decades. Syria has had a civil war for many years. Much of Mali has been under the grip of religious extremists for years.
There are still lots of things that are more easily answerable in games to see if they exist.

For example, can we get AI to play deceptive strategies without being explicitly rewarded (Open AI hide and seek game, StarCraft fog of war plays, etc)?

As to whether it can translate to solving real world problems is arguable (there are some cases yes), but it definitely helps out in weeding inference models or training strategies that are not viable in games (and probably not the real world).

edit: Forgot to list an example. Using the same reinforcement learning strategies not to play games, but to design them.
Or an NPM package works nicely (or .NET assembly, Ruby Gem, Java whatever, etc.)
Great question.

We do believe in Design First Development, where the idea is designed out with the key party members as a part of that group. In this case, it could be the Lead Architect, or Team Lead, or Individual Contributor starting the specification and working closely in source control / pair programming to define that first draft to prevent things tech debt, refactoring, recoding, etc.

Once it's agree'd upon and merged into the codebase, we believe from there, should you setup a pipeline to have it be updated from the codebase, which commits to the repository, that should be allowed as long as the process is kept. So you still have tests against your specification that ensure your implementation works as described, and your specification is validated and enforced with the right policies.

We have some known gaps around policy enforcement and placement that we intend to correct soon. But, this is our belief.

As far as UI driven design, or Text driven design, I personally believe that both can be achieved. Not everyone knows these specifications and having an interface can on-board those individuals and get them ramped up quickly to service the needs and demands of the business.

Where the text form is useful for advanced users, quick changes, automation pipelines, testing frameworks, diff checking, and so forth. So we don't want to ultimately get rid of that layer either.

I think the best approach will be some form of a balancing act. Would love to hear feedback on this.
Nothing about Facebook or Google is inherently addictive. People use Facebook and Google as tools. Hundreds of millions of people around the world use Facebook to keep in touch with old friends and family that don't live nearby, and even (right now) nearby friends and family that they can't safely visit in person. And if there's too many unviewed posts in your queue, you have the ability to easily control which friends you get posts from, and the type of posts you see, and even the type of ads you get if you want to mess around with that. I haven't seen anything on Facebook that tries to get me to buy things or change my opinion other than ads, which is the whole point of ads and is something endemic to modern society and isn't unique to Facebook. If you have a problem with ads, go back 100+ years in time and shoot the NYT editor of the day for introducing the concept to the world.

I don't know what it is about Google that is supposed to be addictive so I'm not even going to try to respond to that part.
I am not sure what the evidence is of nicotine vs inhaled combustion byproducts, but I do agree that the effects are far less. I don't find my questions irrelevant though, even though you have glossed right passed all of them.

The other examples you have are a false equivalence. We can certainly say that nicotine sellers have an obligation to explain the effects of their products and also say that there are bigger public health issues right now. I certainly would not imply that nicotine is the largest public health issue right now. But we can deal with so many things at once.
By this definition you might argue that it's a vitamin north of some geographic line and a hormone south of that line ....

Also, nicotinamide (one form of Vitamin B3) is a metabolite of niacin (nicotinic acid, another form of Vitamin B3). Humans can produce the former from the latter, but require at least one of them from the diet. Does that make niacin a vitamin, but nicotinamide a hormone? They are not equivalent, but as far as "being essential", they are substitutes.

(No idea myself, just rumbling thoughts)