skysight-inc/HackerNews huggingface dataset:
Derek Lowe gives a good overview of how different kinds of vaccines work here: https://blogs.sciencemag.org/pipeline/archives/2020/04/15/co...

The short answer is that there is a bunch of different types of vaccines, and each type has different constraints on their production. Someone who makes an mRNA vaccine isn't going to be able to easily switch to making a live attenuated vaccine instead, for example. Also, first does not necessarily mean best: again, with so many approaches, a vaccine using a different approach can have wildly different side-effects and risk factors. So being second (or even, say, tenth) isn't necessarily a loss.

That said, there are so many projects pushing forward that many of them are bound to fail early. Given the history of cooperation already in this crisis, some of those companies who find their coronavirus vaccine efforts going up in smoke may well choose to help scale out other, more successful efforts--or instead help by taking on more of the current vaccine production efforts, as polio and the flu aren't going away just because coronavirus is here.
Orchid creates multi-hop VPN connections using servers from multiple providers. It uses a private blockchain cryptocurrency to ~anonymously distribute value from users to VPN providers. That's useful because users don't need to trust any single VPN service.

Loki is an onion network. Currently the Session messaging app is the only service implemented, but I gather that there will be others. Loki uses a private blockchain cryptocurrency to hinder Sibyl attacks. That's useful because users will less likely get pwned by malicious nodes.

If those work out, there's no reason why most users would need to even know that blockchain cryptocurrencies were involved.
That actually doesn't sound that hard, it's very similar to writing e2e tests over Selenium (except in this case instead of talking to chrome you're talking to the android emulator).
MMX was integer SIMD that re-used the FPU register file, but was not doing floating-point operations.
YouTubers have known for a long time that certain topics and keywords will get your videos penalized. There is a popular legal channel that refers to the virus as the "My Sharona Cyrus" in order to avoid being flagged. YouTube has been engaged in social engineering for years, and yet there are still people out there who refuse to believe it, or believe it is OK because it agrees with their world view.

Then there is a whole other discussion about how capricious they are in what they decide to promote, demote, and leave alone. You can go binge watch ISIS recruitement videos as much as you want, but try to post a video criticizing Islam, gay/trans issues, etc. See what happens.
I get a 301 redirect to the HTTPS version. SSL Labs shows the site supports TLS 1.0 - 1.3. https://www.ssllabs.com/ssltest/analyze.html?d=krebsonsecuri...
Project management. Honestly, if you can stick to deadlines, you'll be your supervisor's favorite.
This happened to me, payed $110 for a ski jacket, get an amazon box and lookup the price on amazon - $80. I had to applaud the eBay seller for their hustle..
Many PNG readers that I've tested do verify the CRC-32, but there are obviously many that don't. Verification chews up cycles that are useless 99+% of the time, and for PNG, verifying a chunk's CRC32 would delay decoding if the file is being streamed.

I made a CTF challenge about uncorrupting PNGs a few years back; here's a writeup from a team that solved it: https://github.com/ctfs/write-ups-2015/tree/master/plaidctf-.... In this particular case, a PNG was uploaded as "text" to an FTP server, which corrupts newline sequences. A bit of cleverness allows you to recover the original. (The PNG header even explicitly contains "newline" sequences to catch this type of corruption!)
Me too but it still made me gag a little.
People come to the door in my neighborhood for only a few reasons:

- to sell me on religion

- to solicit money for some kind of commercial service, charity, non-profit fundraiser

- to sign me up for political stuff

And they do this several times a week (pre-COVID). So I never open the door to surprise strangers. It's not paranoia; it's just preventing the waste of my time and emotional energy. I'm not interested in worshipping a sky demon. It's not incumbent on me to figure out whether the service is legit, rent-seeking grift on top of a legit service, or a total scam. I don't have to figure out how to gently turn them down just to keep junk food out of the house.
> To achieve good performance, it was therefore necessary to explicitly control how often and when the garbage collector would run to avoid needless interruptions of the main program, especially during parallel phases.

Why? This is a batch program, interruptions don't matter, only the end-to-end time does.

> The goal of elPrep is to simultaneously keep both the runtime and the memory use low.

Why? Keeping runtime low lets you get more work done. Keeping memory use low means what? They are using a machine with 384 GB RAM, make use of it.

Worth noting also that they used GCC 7.2.1, Go 1.9.5, and Java 10. That's a pretty old GCC.

They don't seem to explicitly select a GC with Java, so they'll be using G1. G1 is still not entirely mature. It got much faster between 9 and 10, and somewhat faster from 10 to 11. For a batch process like this, though, the parallel collector is still probably a better choice. Using a newer JDK and a different collector should give better performance - but admittedly, probably won't reduce heap usage.
Because the US regulatory framework and enforcement has been chipped away at by corporate interests over the past 3 decades to the point of non-existence.

America went from filing >50 antitrust lawsuits in the 1970s to ~5 in the past 2 decades.
It's not a bug. 0xfffe+0x0001 satisfies the syntax of a "preprocessing number". In a later translation phase, preprocessing numbers are converted to numeric constants. Not all valid preprocessing numbers are valid numeric constants. The syntax of preprocessing numbers is deliberately permissive to avoid complicating the implementation of the preprocessor.

I'm sure it could have been made stricter, allowing 0xfffe+0x0001 to be treated as 0xfffe + 0x0001 -- but the solution is simply to write 0xfffe + 0x0001 in the first place. The language grammar has to be consistently defined even if it leads to surprises now and then.
You're charging it wrong.
Oh my yes! I had an early beta gmail account. From when you couldn't just sign up but had to be invited by another user.

so my email address is very simple. I have someone from almost every English speaking country who regularly uses my email address for all things mundane, profane, inane and urbane.

I used to respond to each and every one if possible, politely asking them to remove me from the list, stop putting my email down on whatever forms they were filling out or to tell the person they got the email address from to use their own or be more careful when filling it out. It's been going on so long and gotten so bad that I just can't anymore.

examples of things I have received mistakenly in my email that were clearly the result of someone entering them in a form or writing the down to be used by someone else.

Job interview confirmations for fields I am not and have never been involved with

letters from grandma

plane ticket, concert ticket, train ticket, parking ticket and other types of ticket confirmation and notifications.

boating licenses

requests to accept changes to architectural plans for a house

lease and housing agreements

notices to appear in court

electronic receipts of every sort

prescription drug receipts

confidential internal company information

and more.
How Amazon doesn't have a queuing ability for delivery slots is beyond me. This requirement to keep checking back is absurd. My father has Parkinsons and it's very difficult for him to go to the page and refresh it. People don't understand the disappointment of doing a very difficult task to be told "try again later".

On top of that you have engineers in the Bay Area running scripts like ahertel/Amazon-Fresh-Whole-Foods-delivery-slot-finder and taking all the slots before people like my father even have a chance of getting one.
As an intermediate, install windows on the insiders channel, though update 20h1/2004 should be out soon for GA.

I had to jump into windows for a few things last month, and WSL2 on windows has become pretty good and bearable, the Docker beta support for WSL2 also really good... seems to use a bit more memory than I recall. But linux cli with a Windows GUI has been surprisingly bearable... Remote (wsl/ssh) extensions for VS Code invaluable as well.
Sure it does. They are two separate packages, run on two separate network ports and completely incompatible. Just pretend that WireGuard v2 is unrelated to WireGuard. "OpenVPN and WireGuard coexistence doesn't work without a version number going over the wire" would be an absurd statement and the same applies to WireGuard and WireGuard's descendants.
Are you saying that iPhones and iPads are bad at Facebook, Netflix, and Microsoft Word? If they are, the end user certainly can’t tell. If they aren’t, then it doesn’t really matter does it?
is this where I type "who gives a shit?"???????
> I hate to be the one to have to explain this to you. A private entity is deciding...

YouTube is part of a gigantic, public company with more power than many world governments. In a very real sense, Alphabet is more powerful than a hypothetical Standard Oil that also owned one of the most popular two newspapers in every single city in the US.

Their ability to shape markets, public opinion and even elections in 100+ countries is unprecedented and very easy to use with plausible deniability. Facebook is a similar sort of entity. In aggregate, the two control more personal communications than the postal service.

The notion that only a government can be a threat to free speech is outdated and naive.
The Sabin polio vaccine continued to be developed after the Salk vaccine was already deployed for various reasons.
Young people are also drastically less likely to get severe disease, and drastically less likely to be hospitalized, see FIGURE 1. [1] I find it very suspicious that young people who don't go to the hospital with severe disease would require oxygen or end up with life-long lung injuries.

> Everyone needs to stay practice social distancing and shelter, because everyone can carry and spread.

Sweden has demonstrated at national scale that's not the case. [2,3]

The reality is about 60% of us are going to get it one way or the other, so let's control which 60%, and in what order, and on what timeline before everyone stops listening and just walks out.

[1] https://www.cdc.gov/mmwr/volumes/69/wr/mm6915e3.htm

[2] https://www.bloomberg.com/news/articles/2020-04-19/sweden-sa...

[3] https://theconversation.com/coronavirus-are-we-underestimati...
If you don't want PowerShell reporting your activities back to the mothership, don't forget to set

POWERSHELL_TELEMETRY_OPTOUT=1

in your environment before launching PowerShell!
If you stay in an onsen for 45 minutes, you’d probably have bigger issues than infertility — such as passing out and drowning. They of course come at different temperatures, whether they are artificial or natural, but onsen are HOT. After 10 or so minutes it becomes pretty unbearable. Most people take small breaks in between soaks, but even then a cumulative 45 minutes is a bit much.

I’d be more interested in how this affects sauna cultures. In particular Korea where it’s quite common to sleep in a sauna (jimjilbang) for a couple hours. Although people don’t do it daily.
No. Seems to be supporting all versions of tls.
https://www.ssllabs.com/ssltest/analyze.html?d=krebsonsecuri...
The jmalloc script does set the opt level and that's the one discussed in the paper.
> or since int is default type

Not since the 1999 ISO standard.

> int main(){ return linux > unix; }

A conforming compiler must diagnose "linux" and "unix" as undeclared identifiers. Many C compilers are not conforming by default.
> If you have some reliable references, I'd be happy to learn from them!

The problem is that we have no reliable references on the destruction of this library. Written sources contradict each other, and archaeology has nothing.

- According to 3 Roman authors, Julius Caesar burned it. But other Roman authors vigorously deny it.
- Even if no book did burn at this time, centuries of decline followed. The town's activity went down, and other libraries had greater fame.

- When Aurelian took the city (anno 272, thanks Wikipedia), the building was certainly destroyed (among many others) if it still existed.

- There were very late claims that the library was destroyed be the Arab invasion, but this is extremely unlikely since the written sources on the library's activity stopped just before the probable destruction by Aurelian.

In France most people believe in an Arab destruction. For instance, this well known newspaper had to write an justification[^1] after many readers denied the destruction by the Romans mentioned in a previous article. I suppose it is not a mere coincidence that the prejudice against Arabs is very common in this country.
[^1]: https://www.lemonde.fr/archives/article/1990/02/10/qui-a-bru...
No the reason for these types of structures is simply to prevent passive leaks of information which is a far more common occurrence. Any large business is frequently visited by vendors and agencies who also work with others in the industry.

Similarly, if you're presenting externally, it's a good idea to close open applications that are not relevant to prevent info leaks from Alt-Tabbing.

Actually having a competitor pay someone to come into your office to pick locks etc. is rare, comes with criminal liability and is easily detectable on security cameras.
My town (in New Jersey) has a similar law. We have a list at town hall. You can ask to be put on the list. Salesman must not go to your door if you are on the list. Only problem is that charities and politicians are exempt from the requirement.
Probably not anything like $9,800 dollars in one go - there's usually a daily limit. And the scammers may know (e.g. from doing it before) that after a few small transfers, the victim's bank will call him if he had not already noticed, in which case they preempted that call and effectively subverted it for their purpose.

The risk of the scheme not working might be high, but I am not sure that the risk of being caught is much increased.
Guys hire better C++ programmers rather making stupid claims.
Does that block until messages are actually transferred, or just shove them in a golang buffer and return? Now that you mention it I feel like maybe I have seen blocking implementations in golang and Python a while back, which would make sense.
For any test that is not given randomly or universally, there is a selection bias. A test given based on severity of symptoms bias heavily against patients with light symptoms, presumably younger people. But to get from 7% (hospitalized to confirmed) to 1 in 500 is a factor of 35. BTW the city of Canton (Guangzhou) just tested all their high school seniors in preparation for school reopenning and found zero positive case so far. And they did find cases among other groups.

I don't think anyone enjoys lockdown. At a minimum we need sufficient testing, sufficient ppes, sufficient surge capacity and training for standard supportive care. We are still quite a ways from that. Even if death is unavoidable people deserve to have reasonably good care.
We would only put up our Christmas tree on Christmas Eve when I was growing up, and it was ever so stressful watching my father haggle on the tree lot.

My dad: "It's worth nothing to you tomorrow."

Tree guy: "You're not gonna have Christmas?"
"You"Tube. What a joke.

I've been active on YouTube since 2006. Back then I would watch and make comedy videos, but around 2008 I found a love for the political / philosophical side of YouTube. Back then there used some brilliant debates among communities, and I credit early YouTube for being a huge influence on my political views today. It helped me develop an open mind and critical thinking skills that I find immensely valuable in my life today.

But today there isn't really any interesting debates there anymore. I've noticed the algorithms push certain views on me and the creators I like who speak against the YouTube's political views get their lives made very difficult through demonetisations, channel strikes, algorithm discrimination or straight up banning.
In a study like that would half the participants still be in the control group?
I mean, it's an all hands on deck, putting out fires, type of situation after all. So it makes sense for him to be more involved with the daily stuff.
Where I am in Maryland Amazon Fresh has had no delivery windows since before lockdown started. On top of that, I think they recently changed the site to block new customers. Safeway and Peapod have also had no slots. I've been using Instacart despite their hidden and obvious markups because I can get same-day with them while with others I can get nothing at all.

But once this is over I'll start going back to stores, or use a direct seller like Amazon. Inserting a third party into this process seems pointless and inefficient to me - though as current circumstances shows, it does have its advantages.
A refreshing development experience awaits
I did not realize that the WHO's job is to get involved in arguments over borders.

I always thought that their job was to get involved in arguments over public health.
This might be a bit blunt but I am not jesting - an article about disease testing that does not contain the words "false positive" and "false negative" in some form is literally not worth reading.

Even decent antibodies tests can have 10% false positive rates (bodysphere), and lots of those tests have dodgy provenance and 20% false positive is not out of the question.

Here's a better article, thou still not great (paywall): https://www.nytimes.com/2020/04/23/nyregion/coronavirus-anti...

The closest they come to discussing the errors is to acknowledge there might be some: State officials said the test had been calibrated to err on the side of producing false negatives — to miss some who may have antibodies — rather than false positives, which would suggest a person had coronavirus antibodies when they did not. Not very informative, I know.

A word of caution from the NYC health officials: https://www1.nyc.gov/assets/doh/downloads/pdf/han/alert/2020...
Let's try a few others.

South Beach?

LA?

Vegas?
> "I fear there isn't "one truth" out there, despite the content providers' and fact-checkers' attempts :("

Sorry but there is always just one truth. It might be incomplete, but it's always just one.

And trusting the scientific consensus is always the best option period.
The most well known Fascists, were not anarchists. That is accurate enough. I think going so far as to characterize Hitler's motives (as if there was a singular motive) is a bit reductive.
Obtaining a monopoly via legal means is irrelevant if there is then monopolization, the examples given in this thread of "product tying" via Amazon Prime, essential facilities denial via superseding with their own products, and predatory pricing via not having to pay platform fees are all restraining trade.

Whether these could be sufficiently proved is a whole other matter.
I've never heard of Anki before. Was it easy for you to set it up?
This would be cool. I used to rent darkroom space at times and it’s very costly per hour. I couldn’t justify the price and gave up.

Historically I’ve talked to rental darkroom places and the challenges after staff and space costs have been chemical spoilage (lots), and staying busy enough to be worth staffing on a given day. Some places tried to offset by using dev machines (different costs). It’s possible a maker space could handle this better since they scale differently and have a broader customer base.
Sure, but if your business is broken because of a 3rd party library, I'd sooner be looking at patching the bytecode than to write breathless "me too but we are very important" in the bug tracker.
It's more about those that work from the office mostly, maybe go into meetings etc... and then home occasionally (or right now, mostly).

At work, I'm on a dock... at home, I'm on a 4k-kvm switch... so I'm not really using the laptop but for a lighter computers... Just got bumped to 32gb ram, which is most of the laptop bottleneck. Though my personal system (r9 3950x) is much faster than the laptop (i7 8550u) both on 1tb nvme.
I was speaking more to the cost-sharing aspect, which is a big distinction among different systems. In Canada, you pay $0 at the point of care, while other systems (Singapore) require consumers to have skin in the game.

Agree that implementing cost sharing without transparency into pricing is a bad approach.
Would you please stop posting unsubstantive comments to HN? We ban accounts that do that repeatedly, and you've unfortunately been doing it a lot.

https://news.ycombinator.com/newsguidelines.html
Crypto mining is another
> Could they have hidden damage that we can't detect? Plausible. But that is true of many activities. And illnesses

The difference is that we know plenty about those illnesses and activities. This is a novel virus and we are just speculating.

We simply don't know the long term effects of this virus, even in recovered cases.

Until we know this virus well enough to make such statements, we should play it safe.

I for one am not willing to risk a lung because you think it's fear mongering
> Besides, costco is not a monopoly, and I can go to target or safeway if I want to...

amazon doesn't have a monopoly in online retail, and i can go to any other website just as easily. far more easily than you can drive to a different store.
The 99.99999% case scenario concerns videos that are saying '5g caused coronavirus', and meanwhile you're trying to tie up everybodies attention with special cases that don't represent the majority of cases. People get disoriented with special cases and trick questions.

Let me put it this way. If you're not just pointing to the mask example as a tentative, academic exercise, and sincerely believe that they constitute some non-trivial percentage of videos that will really get taken down, you should come out and say so. And if you don't want to commit to that, I have a hard time understanding what, other than frivolous internet contrarianism, motivates you to emphasize those examples.

>do you really think that a discussion about edge cases is so unnecessary?

Yes.
I don't disagree with you. She worries about him and his safety.
If that worked, antivaxers wouldn’t be a thing.
The binding model of WebGPU is nothing like OpenGL. I don't know where you get that idea, especially considering a dedicated section in the article describing this.

Metal binding model works well because each buffer can contain references to other resources (`MTLArgumentBuffer`). So you can change whole packs of resources at once with this. But argument buffers are not implementable on other APIs. We chose Vulkan's descriptor set-like model as the least common denominator.
Also treatments evolve. We were told that ventilators were absolute critical and it appears now that there may better solutions [1]. My point is you can’t enforce a single truth on a topic like that where our understanding of the virus and what to do is changing. And this understanding drives policy.

[1] https://news.sky.com/story/amp/coronavirus-hospital-cuts-cov...
Please don't vandalize HN like this, regardless of how bad an article is. If you don't think it should be on HN, that's what the 'flag' links are for.

https://news.ycombinator.com/newsguidelines.html
None of those laptops retail for less than $1500. The first one you listed is $3999.