skysight-inc/HackerNews huggingface dataset:
By April 13th, there are already 3 vaccine trials are already in progress, 67 other are in potential evaluation [1]

>"...
Three of the COVID-19 vaccine developers have already entered the stage of human trials. These are CanSino, Inovio Pharmaceuticals, and Moderna. Other 67 potential COVID-19 vaccines are still in preclinical evaluation.
..."

From my reading these trials are already global
(Eg IVI, INOVIO, and KNIH to Partner with CEPI in Phase 1/2 Clinical Trial of INOVIO's COVID-19 DNA Vaccine in South Korea )

CanSino is Chinese (HK) company, that already received approval from CN regulator in march to begin human trials
[2]

-----

What are 'WHO global drug, vaccine initiative' has that the trials that are already going on, are overlooking?

[1] https://www.coinspeaker.com/covid-19-vaccines-moderna-inovio...

[2] https://www.bloomberg.com/news/articles/2020-03-18/chinese-v...
I’ve seen some projects succeed with (because of?) visual programming languages and others fail because of them.

My general feeling is that a visual programming language excels as domain specific languages where the domain is quite visual.

Ive seen two problems with visual programming languages which are quite severe in my opinion.

1. Merging sucks. Merging visuals are not straight forwards. I’ve seen companies do trunk based development before it is was hip just to get around it.

2. As with all high level languages, without an understanding about the overhead of different constructs, it is easy to create very inefficient solutions. On cloud systems it may be easy to throw more processing power at the problem. On embedded systems, less so.
We stand corrected then.
Really curious to know. Is it because of the conversational tone or the click-baity suspense?
So the French don't like too much space after punctuation but are keen on space before it. Typography is a weird thing.
Aegis (https://github.com/beemdevelopment/Aegis)
No. It means regulator’s tools are ineffective against the bitcoin network.
The problem with the Stanford study, as I understand it, is that the 95% confidence interval on the false positive rate includes 1.5%, meaning that it is not more than 95% certain that anybody among the people tested was not a false positive.
They actually banned "anonymous coward" posts last year, which was about 10 years too late IMHO. The last time I checked it out, it actually reminded me of the old slashdot just a little bit.
I'm a huge fan of the first 2 plugins, but I didn't know about the per-directory history plugin. I might put that in my toolbox. Thanks for the recommendation!
Bitcoin isn’t meant to interface with existing financial institutions.
JavaScript runs inside your panes so whatever you measure in JavaScript is correct in each pane.
Thank you for your work. Spent way too much time playing this online with friends and family!
Come+Correggere+l\&#039;Errore+404+Not+Found+nel+Vostro+Sito+WordPress
Outside? It's weird, because I've been to a restaurant in Vienna and they had a three by two metre windowed and ventilated smoking compartment where smokers were enjoying their habit. In my country it's completeley banned in closed public spaces as it should be.
> I suppose that this "right-wing Tory supporting organ of Rupert Murdoch" is "effectively defend[ing] Corbyn and his policies" for a simple reason

No, as I stated in that sentence you are quoting from, that is exactly what they are not doing.

> In truth, electorally the Tories would far rather face Corbyn and the tankies at each election.

They faced Corbyn less than three years ago and failed to secure enough MPs to form a government by themselves and had to bribe a loony right-wing extremist party with £1,000,000,000 of British taxpayers' money to grab power[0].

In that election Corbyn received a (far) higher percentage of the vote than every winning Prime Minister of the previous three elections, including Tony Blair in 2005.

So no, what you said is not even remotely the truth, which is exactly why so much time, energy and money was spent trying to destroy/remove Corbyn.

[0] https://www.independent.co.uk/news/uk/politics/theresa-may-d...
The misfortune isn't that Dev's aren't doing anything. The misfortune is that loud mouthed people on places like this are opinionated and dumb. I just read a comment where the poster said json should be mandated by law because a free service didn't provide json. And he is definitely not fringe, this is 90% of the css philosophers here. He has 37 000 points. Ye ls 37 thousand.
Ay, no. You can't rewrite history in upstream branches, no (well...[0]), but you _can_ (and should) do it locally.

There's this terrible misunderstanding that "git rebase means rewriting history, which is bad" when in fact rewriting history locally (before you push upstream) is fine and quite desirable.

[0] In fact you can rewrite history upstream if you really must, but then you have to securely communicate to downstream users how to recover by telling them the previous HEAD commit and the new one so they can use git rebase --onto. If you really wanted to, you could make a habit out of this and make it work just fine. Most projects just aren't set up for this.
PCR is pretty selective for SARS-CoV-2
>Yet, our citizens are out and about intentionally going against guidelines.

People don't like being under house arrest? What a surprise!

>Can we really compare conscientious Swedes with bold Brits or brash Americans

Of course we can. Quit giving them credit as more moral and complaint when not as much has been asked of them.
I think they are bound to. You don’t think as soon as Disney can they aren’t going to start showing ads for everything Disney related?

The worst step back to me from TV -> streaming -> streaming becoming more TV like is content release schedules. The Mandalorian on Disney Plus was a great example, you have all the episodes ready and there isn’t a good reason to keep them sitting behind a time gate. I would be much more likely to subscribe for a month to watch a show in a week than I would be to subscribe for a few months to few one show. Instead you get none of my money
I'm not convinced that spreading the BC breaks over more Python major versions would have been more helpful or worse ... Hard to say of course, will we ever know for sure ? It seems to me that the problem would have been multiplied.
Reflections on hackathons, open-source and startups
Thanks. Small typo: the second removeprefix() should be removesuffix()
The old thinkgeek.com -- though shipping to Canada was atrociously expensive and you would always get hit with customs.
Now if only politicians learned a thing or two from this guy.
Not possible however: scientists talk to brains, politicians talk to bellies and appeal to instincts, which require them to appear strong by showing self confidence and never admit any errors.
I think about the depression era behaviors that stuck around in my grandparents as a good example of what to expect coming out of this pandemic. They learned certain things out of necessity and it changed their worldview on everything from darning their own socks to what ingredients they'd use in their cooking.

I expect that many of us will carry similar behavioral scars for years or decades later - ensuring we have masks on hand, unconsciously observing social distancing, being wary around crowded spaces like airplanes and airports. I don't know what all those behaviors will be, but there's no way we avoid carrying at least a few with us.
- we’ve stopped using ^ and ~ because of the unpredictability of third party libraries and their authors’ potential for causing our own apps to break. We also find ourselves forking and managing our own versions of smaller/less popular libraries. In some cases, we’ve chosen to reimplement a library.
That’s a fair point, I was conflating it with a negative income tax when I said that. You’re right, there are advocates for UBI that would maintain all social programs too.
Hand sanitizer is ordinarily considered a medical product, and is subject to FDA controls. (Medical grade in this context means United States Pharmacoepia [USP]) The requirements for anything put into a medical product are stricter than those for food and drink. That doesn’t mean that it’s any cleaner per se. The link below describes the situation from last month, since then the FDA has temporarily relaxed the regulations to allow compounding of sanitizer using other grades of ethanol. https://www.google.com/amp/s/cbs2iowa.com/amp/news/local/eth...
> This is a night vision test developed and published by WD Wright in WWII. It relied on a radium light source (sadly no longer available) to provide a calibrated, low level of illumination.

So this is an equipment to test human vision in the dark, not related to EO “nightvision” technologies that the term more commonly refers to today.
I don't fully understand the relation between the difficulty of the work, the luck involved, and upside vs downside. I don't even know what you mean by the "downside", is that the downside of making the mistake, or the downside of not making the mistake?

I'm saying the downside of making the mistake (for her) might be larger than the upside of making the mistake. I don't think that's obviously wrong.

But my real main point is that speculation of this kind (in either direction) isn't very productive.
Neither you nor any of our current politicians are anything like Churchill.

It is not enough to mandate belt tightening during a crisis, you must also get out there and give a rousing speech so people will want to tighten their belts.

If you just provide “good” policy, but no framework to make it palatable then you have failed before you started.
No insurers will underwrite against a nationwide shutdown caused by pandemic (or war or other meteor strike or any other similar economy-halting event). They'd literally go bankrupt the second they start paying out because the idea of insurance is that not everyone tries to cash out at the same time. That's why you typically see all these plans, business interruption insurance included, make exceptions for exceptional events.

And before someone links the Wimbledon, they have bargaining power beyond most companies' capabilities, and their insurance was custom written. There's no way standard businesses will ever be able to get insured against pandemics.
Pricewatch! So many memories as a kid in the late 90's/early 2000's scoping parts for my desktop on that site.
The remake looks promising! I like ET Legacy and even contributed a tiny bit, but I think it would need a remake for my friends to play, for example...
"Does it have to be this way?"

Yes, pretty much.

I'm really struggling to deal with the odd economic intuition here in the comments section. I'd urge readers to start to think about how every bit of the economy is interconnected and that it just can't magically 'stop'.

"Alberta's premier, Jason Kenney, unveiled projections for the province's unemployment rate on pace to reach 25 per cent." [1] and this is in the short run!

Have a look at this jobless claims graph [2] - and it's already out of date.

Even if we could magically deal with massive reduction in GDP (maybe we can, but probably not) - the economy cannot realign itself quickly.

Such an adjustment would take decades to do organically. We have no ability to centrally re-allocate every aspect of the economy. We can do it in some parts of some of sectors - banking and finance for example (sometimes with mortgages), but even that is risky and very unfair.

It's not just 'airlines' - it's vast swaths of the economy, that take down other parts of the economy. At least travel, energy, tourism, hotels, restaurants, entertainment, most manufacturing - just to rhyme of a few are 'shut down'. That's a monster part of the economy.

" Why not put certain things like rent, utilities, mortgage payments on pause--even if just for those on furlough?"

Because everything is connected ... the money that goes to your rent, utilities, groceries, gas, it's not some magical place obviously. There are economic endpoints there, jobs, consumption, taxation - and a lot of them.

The banks employ millions of people doing lending. There are millions of people that act as landlords and who depend on that income. They're also mortgaged often. Utilities employ a lot of people, they also buy services.

And what about the people like my parents who don't rent and have no mortgage?

Consider the both the scale and timeline of the economic intervention right now: we are printing money and doling out literally Trillions of dollars (!!) very quickly, willy nilly. Unbelievable numbers. What this means is the government/central banks are realigning the economy temporarily and 'deciding arbitrarily and quickly' who is going to win and lose - and then putting off payment to taxpayers in the future - and this will last generations. This is happening on a global scale.

If that's not shocking enough - all of this is a temporary fix! All these massive bailouts won't last very long.

The various programs announced in Canada for example last about 4 months, but Covid will last probably 18-24 months.

Again: Contact tracing (with intervention) is not only a reasonable solution, it's basically the only current viable option to get going outside of a cure or vaccine.

[1] https://www.cbc.ca/news/business/jobs-unemployment-rate-covi...

[2] https://www.businessinsider.com/us-weekly-jobless-claims-rec...
As a developer myself there’s a constant struggle regarding how marketingy I should make it. I don’t think I’m making any over-the-top claims and there’s no denying it works, but different people respond to different things.

What were the phrases that most annoyed you?
Given that 11 Pro features are accessed as soon as you touch the prominent zoom UI, and that Night Mode is automatic, that seems unlikely, but I would like to learn more. It doesn’t seem like public data is readily available after some searching.
Canada is a very large country with a wide variety of water. I'm quite surprised that you were somewhere where you were able to smell/taste chlorine in the water as that has not been my experience, but at least one other commenter seems to agree with you. That said, small amounts of chlorine are perfectly safe.
Introduction to Couchbase for MongoDB Developers and Experts
That's tremendous. That type of brazen not-give-a-shit is impressive to me, as abhorrent as it is.
I'm also making enterprise-grade software with quite a few external dependencies. I had to email the developers of the biggest dependency multiple times because of bugs but they were all fixed within a few weeks in a new patch release. They also went out of their way to provide me with workarounds for my problems. In the NPM world you are on your own.
To give evidence to this comment, the gp's source notes that ~75% of those that tested positive for covid were >60 years old. Whereas the BOP [0] reports a distinctly different age demographic. We know that covid dramatically affects people differently based on age, so I wouldn't suspect IFR to be similar to that of a cruise ship (where it is typical for the demographic to be older and retired)

[0] https://www.bop.gov/about/statistics/statistics_inmate_age.j...
Yes, this argument is one shared with some arguments for minimum wage. When a sector of the economy can set wage freely, it often races to the bottom on price competitiveness, neglecting automation and training improvements; businesses that attempt to raise their quality get pummelled by the higher costs and risks relative to competition. A rising minimum wage standard therefore encourages modernization of the work environment.

With UBI a similar effect is had on the demand side: If you assume a higher base of income, then consumer credit, payday loans, friends-and-family-favors, etc. become less of a necessity for low-income workers. Higher-income workers with long-term debts like mortgages and student loans become free of their debt more quickly, and face fewer consequences if their income takes a hit. The workforce is therefore disentangled from a set of predatory financial interests that chain them to needing their current job and to stay in the good graces of their financial backers. Even a very small amount of UBI will create a substantial reduction in poverty traps, domestic abuse, and labor mistreatment.
I may be old fashioned, but as someone who went through the dotcom crash I will never buy Microsoft.
There really isn't much of a correlation of density and fatalities, even if New York City may create that impression.

Even in New York, Long Island and Westchester County have more cases per capita than New York City.
How to Start Preparing for a Career in Investment Banking?
Yeah, that's sort of what I'm thinking. I guess I need a good review site for linux tablets.
DVDs don’t have DRM????
Rushing to develop a vaccine could backfire
Thailand just yesterday reported some.
It doesn't matter if we know precisely the details of Covid spread.

Obviously that information would help.

Irrespective of how Covid spreads - we know for sure that:

a) Total lockdown works.
b) Contact tracing works.
c) If you have 0 cases and you have good borders (like Taiwan), you can keep it out.
d) Nothing else works.

Option B is our only way to stay alive.

Those 'superspreader' references you pointed out will help us refine the terms of 'contact tracing' solution, but probably not abnegate it entirely.
Actually Latin is still being developed, as official language for Vatican documents and they have language experts to update the dictionary for modern terms to keep the language updated.

Telephono mobili Android decurrit
The Spectrum Next seems to be the closest to the ideal, and obviously it's perfect for Spectrum fans including me, but it's missing:

• A built-in display.

• A platform not tied to imitating an older platform.

• A language not tied to an older language.

As for the others, despite being commendable efforts, they're also missing one or more of:

• Usable straight out of the box; no assembly required, and without need to connect and update the system first.

• A single official repository (not excluding others) for sharing and distributing user-made programs, accessible from the device itself as easily as the App Store.

• Standard keyboard AND standard game controller (most have only one or the other).

• No fragmentation: If you wrote a program for the Commodore 64 or ZX Spectrum, it would run on 99% of the C64s or Speccies (the only differences that I can recall were the 48K/128K versions, and things like "speech" packs etc. but we don't need separate "upgrades" like that today).

As "blondin" commented:

> i see people talking about the arduinos, raspberry pis, and all these micro devices for which you have to pick additional components among myriads and you will be very lucky if 10 more people have the same setup that you have. these people are missing an important point about platform and sharing here.
IDK, for me it looks more like a taste map than a quality map. In Spain northern regions have almost perfect water where mediterranean regions do have taste and more problems due the nature of their sources of water. I mean, it's not very useful. You'd drink tap water in my city or Madrid, you wouldn't like it in Barcelona, although you can.
Artificial Intelligence vs Machine Learning vs Deep Learning
> Configurations are likely to change as carriers try to squeeze more money from customers.

If that’s not what they were already doing, I wonder what that will look like.

Anyway, it’s not necessarily bad. Air travel was way too cheap considering its externalities.

I know someone who _commutes_ by plane because their office is two countries over (in Europe), they don’t want to move to the much higher COL country where the job is, and the office won’t let them be remote with the same salary. So every week twice a week, they fly. And it’s still cheaper than living next to the office. This insanity and many like it must stop, it’s so much pollution for completely stupid reasons.
Covid-19 India – Live Update
The Great Onion Corner And The Futures Market (2015)
I have heard that with commercial space you can take building depreciation costs and write that off as an expense so it might be not as expensive for a landlord to keep the property vacant as you would imagine. Also sometimes as I understand it is new tenant who has to clean up and bring the building up to code to open, and if there is plenty of other properties to lend they might find something with less upfront costs.

Location is everything in cities like NY, especially for businesses that rely on people traffic so few hundred feet closed to rail station might be a lot more expensive so they just wait for tenant that can utilize that.
It's not really one website per se, but finding someone's old website that they'd built up over the years in the '90s with all sorts of interesting, detailed, yet approachable content. Sometimes academics, sometimes just people with interesting hobbies. There's a certain je ne sais quoi about them that most blogs these days just don't have, and I could get lost in some of those sites. Every so often I still find one, and every so often I find a site of more recent provenance but with the same quality, but overall they're a rare breed.

One of the most recent such sites I've found is actually someone's Angelfire site, rather than their own domain: http://www.angelfire.com/extreme4/kiddofspeed/cherlinks.html . I went down the rabbit hole of her Chernobyl content way too late at night one day in February. All sorts of interesting content based first-hand experience.

The other thing I miss is desktop-focused instant messaging that focuses on the text experience. I had so many great text conversations on AIM, and GChat when it was new, sometimes over the course of hours. Just this week I had my first AIM conversation in at least a couple years, and it still had the same magic. Probably the closest thing to it we have today is Slack, but the ubiquity of all your friends having AIM (or at least Yahoo! Messenger or MSN) just isn't there.
Which country exactly would be disrespected in this case? :D

On a serious note, Italy indeed has some tap water problems https://en.wikipedia.org/wiki/Water_supply_and_sanitation_in... , although common sense and the internet telling me that I'd rather drink tap water in Italy than in Tunisia...
Actually Cobol got its latest ISO revision in 2018, so it is more Python and less Python 2.
‘Deficiencies’ that broke FCC commenting system in net neutrality fight detailed
WebMonkey was right up there with w3schools in terms of teaching myself how to code for web in ~2000
Belgium having the same quality on the map as the Netherlands shows me that the source of then information is wrong or the scale isn’t nuanced enough to be of any use to me. Belgian tap water should, on any scale, be at least a category lower than Dutch tap water.

Belgian tap water is horrible compared to Dutch water. Source: I lived in Brussels for 5 years. Could be just the brusselonian water, but there is a reason that bottles water is a thing that everyone buys in Belgium and practically nobody buys in the Netherlands.
Is there technology available through which we can change voice in real-time on phone calls, I assume for it work latency has to low.

There is this project
https://github.com/CorentinJ/Real-Time-Voice-Cloning

But I found it pretty hard to run, and it doesn't have voice input.
Yes Leaflet in combination with a CartoCDN basemap
No one here has heard of it probably but I hung out so much on kazibao.net (a francophone website that was moderated for kids to chat and discuss stuff) as a kid. That and the old icq. I can still hear the obnoxious “UHOH!” tone in my head from receiving a message.

Oh and hotline on the Mac.
Hand written 294 lines vs. gcc -O3 526 lines. https://godbolt.org/z/yEcMKf

At a first glance, it seems the compiler version is better at hiding the latency of some of the div instructions. It might be hiding memory access latency, too. But that's more involved analysis.
But who’s using them? From the symptoms you describe I would guess it’s people very far removed from software development.
! Promotional !

please remove