skysight-inc/HackerNews huggingface dataset:
I have looked into altitude and NOS activity a lot because of the issues I have at altitude as well. This is largely controlled by the genetics of NOS2.

https://www.sciencedirect.com/science/article/pii/S000292971...

And there is a clear link to low NO and CF

https://www.cysticfibrosisjournal.com/article/S1569-1993(05)...

It seems the issue with CF is NOS1. (I have an issue with NOS2)

https://www.atsjournals.org/doi/full/10.1164/ajrccm.162.6.20...

Look at the cofactors that help NOS1 function and that might give you some clues at what may help:

https://www.uniprot.org/uniprot/P29475

Glutathione will help protect against both BH4 depletion as well as forming peryoxinitires.

You intuitions are excellent.
I couldn't do without a 'bookmarks' feature that I implemented for my terminal. It's triggered with `Alt+b`:

1. Scan an eternal history file for `cd` with absolute path except for /tmp/*

2. Sort and filter out duplicates

3. Call fzf and let user pick the desired result

4. Upon selection don't enter the directory but instead type `cd <selection>` into the prompt so that the user can navigate further using <Tab>.

What's nice about this approach is that it automatically builds your bookmarks, but only from `cd` commands where you deliberately used an absolute path.

Here's the code. It has some prerequisites (fzf[0] and ~/.eternal_bash_history[1]) and probably only works with my terminal (Xfce Terminal); it took a bit of tinkering to get it to work.

# ~/bashrc.d/aliases.sh
__b() { # bookmarks; props to fzf for providing examples of READLINE configuration
local selected="cd "$(cat ~/.bash_eternal_history | grep '^cd /' | egrep -v '\.\.|/tmp' | awk '{print $2}' | sort | uniq | fzf --exact)

READLINE_LINE="${READLINE_LINE:0:$READLINE_POINT}$selected${READLINE_LINE:$READLINE_POINT}"
READLINE_POINT=$(( READLINE_POINT + ${#selected} ))
}

bind -m vi-insert -x '"\eb": "__b"' 2>/dev/null

[0]: https://github.com/junegunn/fzf

[1]: https://stackoverflow.com/a/19533853
You can detect binary patching. You can’t really detect patching if they have control over the whole source.
It's also worth noting that rockets have been done before.
CSGO matchmaking is still rife with cheaters. Valve has put a ton of work into VAC, but if people want to cheat, it is still very possible. It prevents matchmaking from being taken seriously as a competitive ladder. Even when I’m just playing casually with friends, it’s stressful when I basically have a 1 in 10 chance of the opponent cheating, and I need to sus out whether they’re actually good or just cheating.

I pay for ESEA, an external service, which installs a kernel mode anticheat. ESEA also got sued for running a bitcoin miner on users computer several years ago. But it’s the only way to get any semblance of real, high level, competitive play.

This is the context for Riots anticheat. They need to provide a solid AC from the start to pull over players and provide a competitive matchmaking system that isn’t a total joke like Valve MM. It sucks, but I know who I’d trust more between Riot and ESEA. I just run my games in a separate partition and bitlocker my primary OS install.
I believe it is not correct. You can put new features that do not exist in the physical world in a simulation. For example, you can double the number of quarks in a proton as long as you define a mathematically consistent interaction to allow so.

Then you created a richer simulated world.
Google Chrome display locking fuzzing
Dendrocnide Moroides
You describe fancy advanced algorithms, meanwhile almost all mainstream FPS game servers happily accept client reporting arbitrary player position teleportation without the smallest of hitches. Not even the most basic server side validation.
Supreme Court to hold May arguments by teleconference
The UX or the UI?
My productivity workflow, that I don't hate
Someone paying not just for a dev but a dev with significant domain knowledge in a niche area.
This is cool, in any case.

TL;DR: DustMite feeds reductions/variations of a data set (like your source code) into an oracle which tests if it satisfies some property. The primary example is reducing your source code to a local minimum that still exhibits some compiler failure.

The article's conclusion notes some other cool uses; my favorites were:

- "reducing a large commit to a minimal diff"

- "reducing a commit list, when git bisect is insufficient due to the problem being introduced across more than any single commit;"

- "reducing a large data set to a minimal one, resulting in the same code coverage, with the purpose of creating a test suite;"

- "if you have complete test coverage, it can be used for reducing the source tree to a minimal tree which includes support for only enabled unittests. This can be used to create a version of a program or library with a test-defined subset of features."
> I'd be less critical of them if they were submitting PRs instead of just bug reports.

See, this is what's bizarre to me about this particular problem - the kind of people who (1) worry about these types of things and (2) are running CLI software from Github should be capable of figuring out how to implement the feature(s) they want and submit pull requests instead of opening issues. This is FOSS software, the price of entry is $0, so I don't get how people think they're entitled to any particular feature without implementing it themselves, especially features as marginally-useful as not requesting fonts from Google.
"The new disease came."
Keep in mind that contractors can put up to $57k per year into a retirement account and can deduct 20% of income from the QBI deduction which will drastically reduce your taxable income.
Show HN: Betanotify.com – Track and experiment with early user sign-ups
I meant to say “informed-consent”. I’ve edited the post.
I saw one of the threads on reddit about this yesterday with the usual litany of privacy/security complaints and had a random idea - make it optional. Put people that decide to remove it in an alternate queue with server-side anti-cheat mechanisms only, maybe disable competitive/ranked game types for them.
Can you imagine mobile devices that are not built to extract the maximum possible profit from the systematic exploitation of people's private data and attention spans, leading to political manipulation and instability, all to further fill the coffers of the global elite, who already own most of the world?
Amazon Seeks to Hire Another 75,000 Workers
I find myself going to the youtube videos a lot. There's a lot of new concepts in Fulcro. I'm surprised how long it's taking me to figure it out, but I haven't given up yet, and so far I'm liking it. I'm hoping that the investment proves worthwhile.
This is true if you assume that the simulating world is what’s being simulated in the simulated world. That is, if bacteria exist only in the simulated world, then if you’re a bacterium there’s 100% probability that you’re simulated.
There’s a thriving market for turn-based games that do not depend on reflexes for competitiveness. I played one this weekend that was a top-down scroller shooter converted into turn-based.

It’s cheating to try and remove for yourself only that reflex-based competition from games that are built on it, and it’s draconian (and not fun) to suggest removing all reflex-based competition from all games.
Maybe a different language from English should be used for the CMYK names to allow ambiguities when translating...
Ocarina Of Time on Unreal Engine 4 – 100% Walkthrough 1h33m45s
Don't forget the third option: ignore high-consensus advice from health experts, contract a novel deadly disease, and spread it, become seriously ill, or die.
I can't compare it to Dreams as I don't own that one but as performance goes it's certainly no Unreal Engine but you can do impressive things with it without too much effort.

I did a VR game in Godot [1] which was my first ever VR game and my firt Godot game and it turned out pretty OK without too much friction

[1] https://www.vrworkout.at
Nice lists. I made a game for playing Boggle with family that you're welcome to add to the list of games browser games to play with friends:

https://wordgame.paulbutler.org/
Easter Egg Hunt in a Google Sheet
The administration of this new reactor's construction was a farce from the beginning: they expected to be able to build this reactor in half the time and half the price it took when France was building 10 reactors in parallel, ie when it still had experience. There is no doubt that the estimation was not just optimistic, but unrealistic (not my word, the word of the rapport on the overblown budget of this reactor)

That said, it's still going to be a good amount. The danger that too many people do is that they don't understand the amount of power a nuclear plant produces, especially when they compare it to wind turbines or photovoltaic panels.

The construction of the entire French fleet of reactors was done for 100 billion current euros, and you can clearly see the effects in terms of CO2 (https://www.macrotrends.net/countries/FRA/france/carbon-co2-..., starting in 1980). If you consider the changes in safety thresholds, rebuilding it anew is in the order of 300 billion euros. 300 billion euros is the amount Germany spent between 1996 and 2014 to build renewable capacity, and yet their emissions of CO2 barely dropped (https://www.statista.com/statistics/449701/co2-emissions-ger...).

A wind turbine or a solar panel is cute if you're talking about powering your own home (even though you'll need more than one) but if we're talking about an entire country with its industry, it's far from being a viable solution. It's always been a problem of scale.
Love it. Well done. FPS meter seems to be a little crazy, the rest looks great
> Sure, if our measuring stick is information, then there is no difference in kind, merely a difference in complexity. But the complexity difference between the two is worlds apart, thus substantiating the distinction I'm pointing to.

I agree 100% that computational complexity can be used to make a meaningful distinctions. It's not clear that that's the case here though. That is, I agree that the quantity of information is worlds apart, but if the information content is all of the same kind and requires no special changes to the computational model needed to process it, then I don't think the magnitude of information is relevant.

> For something to be intrinsically contentful, it has to intrinsically pick out the intended target of reference, not merely be the source of entropy from which another process picks out a target.

I don't think this distinction is meaningful due to the descriptor "intrinsic". It suggests that an agent's thoughts are somehow divorced from the enviroment that bootstrapped them, that the thoughts originated themselves somehow.

The referent of one of my thoughts is an abstract internal model of that thing that I formed from my sensory memories of it. So if "instrinsically contentful" information is simply information that refers to an internal model generated from sensory data, then this would suggest that even dumb AI-driven non-player-character/NPC in video games have thoughts with instrinsic content, since they act on internal models built from sensing their game environment.

> But to deny the notion of intrinsic content because you can't currently write one down is short-sighted.

Maybe, but I'm not yet convinced that there's real substance to the distinction you're trying to make. I'm all for making a meaningful distinctions, and perhaps "mental states" driven by internal sensory-built models is such a distinction, but I'm not sure "thought" or "information with intrinsic content" are necessarily good labels for it. "Thought" seems like overstepping given the NPC analogy, and per above, "intrinsic" doesn't seem like a good fit either.
I don't know of any, but that isn't to say there isn't any. Oracle on the other hand is widely known for this practice.
Smartphones. Holy crap. Remember arguing about some objective fact and having to "agree to disagree" at some point?

We lose those kinds of social events (I liked them), but I think we are far better off. All this knowledge instantly accessible.
I'd like to find online chess with video chat is there such a thing?
Why the foul language? Completely unnecessary.
It feels like it wasn't designed, but grew.
I'd add https://skribbl.io/ to the games list, it's basically pictionary.
In US culture, using "swear words" is still taboo for many people. (I'm not saying it's right or wrong).
> Hiring managers should definitely not be assuming that all programmers do apps in their spare time.

It baffles me how much this is an assumption. Like all the developers should not have any hobby that doesn't involve coding.
Yes, absolutely right. The core tech. between crypto-valuations and tech-valuations stayed the same. It was basically: Python + spacy (plus a lot of different supporting libraries).

Some surprising aspects:

For tech-analysis, you can accomplish a lot by using a rule-based parsing because the source texts (e. g. patents) have the same sentence structure. In fact, several researches have shown that patent text follow a certain text structure (e. g. SAO, i. e. Subject-Action-Object).

For crypto, this was for more difficult as the text structures were all over the place.

Also, crypto-analysis ("back then") was very messy because it was difficult to find a trustworthy data set. With technologies you can confine it to Wikipedia, patents, scientific papers. There is still a lot to analyze, but at least you have a somewhat official data set.

Also with crypto you have far less data points per company/token/coin which makes it hard for a machine to not disregard it as noise.

Similarly, with tech-evaluation it seems that - because you get so much data from one document (e. g. one patent) you can often disregard a (big?) portion of it and still end up with good results.

Additionally, it seems to me that crypto-analysis was supposed to be far more numbers-heavy (how much funding etc.) and thus the tolerance for error was relatively small. E. g. if you miss one funding (out of three) you can change the company's valuation up to 50%. This happened to me basically all the time which was super frustrating.

The last surprising fact was how difficult and complicated keyword extraction is. For crypto evaluation I just went with relative word frequency (the more a word appears in a text the more important it becomes, assuming it does not appear in all the documents). However, as I have learnt with tech-evaluation, there are maybe four of five strategies for keyword extraction. And this is still an area where I have not found a solid solution for my NLP-case.

Finally, after all the reading that went into building researchly (which is relatively little) I have realized that I know significantly less about NLP than I have initially thought. It still fascinates me what kind strategies/algorithms people come up with.
> Your WPM is limited by the speed of your mind!

I mean... it already is. This tech is highly unlikely to surpass keyboards for a few reasons:

1) It needs to be customized for each user.

2) It needs really special hardware to read an accurate signal, especially if there's no open channels to connect to via a missing limb.

3) The accuracy / speed tradeoff for muscle twitches vs. touch typing can't possible be that good. The signal to noise ratio of brain impulses is bad.

4) The limiting factor on wpm typed for any original work of non trivial length is going to be your thinking of the idea, not your typing of it.

5) Imagining the tech worked perfectly, such an interface would probably be very mentally draining to use. Typing out a passage is easy to imagine doing, but editing existing text? I feel exhausted just thinking about it.
The Real Cost of Free (2010)
DFW in IJ: "The clichéd directives are a lot more deep and hard to actually do. To try and live by instead of just say... So then at forty-six years or age I came here to live by clichés... One day at a time. Easy does it. First things first. Courage is fear that has said its prayers. Ask for help. Thy will not mine be done. It works if you work it. Grow or go. Keep coming back."
None of those are beyond hobby level, though.
Well, not everyone is okay with profanity, some people may be upset by it.
The blocking factor for that scenario is that the hardware to do that kind of cheating isn't cheap enough that the majority of cheaters can afford it. Get it below maybe $100 or so and then it would become a real problem.
If anyone is interested, CurrencyFair are another excellent way to save money on international payments. Similar to Transferwise, you can send money fast from one currency to another at the current exchange rate with far less fees than a bank.

They also have a peer-to-peer element, where you can choose your own exchange rate and wait for another customer (sending money in the opposite direction) to accept that rate. If you are willing to wait a little longer to send your money, you can get excellent value using this feature.

They currently have an excellent sign up offer at the moment that you can access using my link: https://www.currencyfair.com/rafland/?channel=RMZIY1

(Disclaimer: I currently work there. I love the product and I know you will too:))
"Hi Grandma! Check this out..."
Move to Python3 and some breaking changes in the extension API along with other big changes like theming, proper high DPI support, 64 bit & native app on mac. Then the usual glut of use case feature improvements to boot.
Imagine a crazy tycoon on a gigantic barge in the middle of the ocean using gigantic nuclear reactors to direct-carbon-capture CO2 into fuel and then selling it to become a 21st century petro power.

I want to see this movie.
I'd add https://pandemicvolunteers.org to coronavirus resources. It could provide the best relief.
Heyyo "Hacker News Orange [0.123]" is ranked #5 now.

Edit: I think my new favorite is "#403403 Forbidden Brown"
I never met Conway myself. But I first encountered his Game of Life in a science fiction book I no longer remember the title of. The book didn't make much of an impression but the game did. I played it out on paper during long car trips and when we got our first computer the first code I ever wrote that wasn't "hello world" was an implementation of Conways Game of Life in gw-basic.

In a way his game helped start me on the path to the career I have now.
Not using them. Its amazing what you can accomplish with a plain text editor and your brain. Ever seen a presentation that didn’t rely on PowerPoint? It’s such a refreshing thing to witness. How many Excel “applications” have you used that actually worked as intended consistently and weren’t just a giant time suck that would be better spent building a simple form over data app?

Ask yourself this: When was the last time you truly needed MS Office to produce something of value? Not imaginary enterprise “I look busy so I must be getting things done” value... but true value.
This sounds like a valuable resource, and there's a lot of good stuff on this page: simple call to action, clear understanding of my needs (get first 100 users), and proof that you're using a service that I trust (CovertKit) to send the emails.

Here's why I didn't sign up:

1. I have no idea who is offering this newsletter and what their accomplishments and qualifications are.

2. I have no way to gauge the format and value of the information I'll be receiving.

Fortunately, these are pretty easy to fix: all you need is a photo and short paragraph about yourself (with links to projects that give your advice credibility) and a couple of links to example emails for users to read before committing to signing up.
React Native- Getting started with a brief guide
It's a naive viewpoint. Prime example: Counter strike. Even with VAC(valve anti cheat) measures, the game is full of cheaters. Those aren't super intrusive, and the game simply isn't fun for anybody who cares at all about competitive gameplay. So people move onto other platforms that support more intrusive anticheats. I'm not really sure what the solution is, but given your stance, that would just mean every FPS game will be rendered borderline unplayable because of all of the cheaters on it. And I mean, if that's your point--to just not play competitive FPS games, then I'm not really sure what we're even arguing here.
I was thinking of compiling a list of made in non-China items.
How to Back Up and Restore a 10-TB Cluster at 1 GB/S
I wonder, what apps and services it helps improve? Why would you want to turn bluetooth off but not really turn it off?
CSS Variables for React Developers
This is going to drive the “Is RBG actually dead?” conspiracy people crazy.
https://slatestarcodex.com/comments/
Show HN: A system for freelancers to be paid with 100% certainty and on time
last I looked at it a few years ago, Cocos2D was a pretty good balance between powerful and newbie-friendly. The tutorial started from the basics of what makes a game program and built up from there. Quite a nice engine for 2D stuff.
Because people are annoyed when forced to stay home. The language reflects this.
VR Headsets on Steam Reach 1.7M
Too bad it’s censored.
> There are countless ways engineers choose to spend their off hours. Some contribute to open source. Others take online classes. Some are tutors, and others work a second job as a freelancer.

It's called off hours for a reason. Being a tutor or a freelancer is a second job.
> What's the opposite of pedantic? "Colloquial"? Please tell me.

It's surely not the answer you want, but 'unpedantic'.

If we can extend to more than one word you could describe someone as not being too concerned with the finer detail or nit-picking, or as 'glossing over' minor errors or trivialities.
Another point to make is that iOS also made it a bit harder for the user to completely turn off bluetooth and wifi from the control center since iOS 11, possibly allowing scanners and beacons to pick up these devices from passers by. Unless you directly get into the setting screen and switch it off.

Sure Apple keeps Bluetooth/Wifi on for 'Find My' services but I'm pretty sure it will also be used for the contact tracing technology use case since many users will falsely believe that it is completely off when pressing the switches on the control center.
Perhaps one loves Google and would like to help them increase their understanding of the world.

on edit: changed you to one and your to the.
Please, tell me. Kidding, but also not. Honestly, I am still unsure. I started working on it because I came across those features in different papers (if I remember correctly - by accident) and thought they were cool. So I started working on it.

But "creators and inventors" goes in the direction I was thinking. Additionally, innovation consultants, tech. advisors, "policy makers" or people who have to decide on technology but lack technical expertise in certain fields, engineers...
you mean, like having people to remember to bring their house keys when they leave so they can get back in? Yes, it's an extra step that has nothing to do with the task I want to complete, but the price I pay is totally fair for the security I get for it.
Probably apps like Tile, that don't need to have full Bluetooth connectivity, but still want to scan for Tiles every once in a while.
Hi guys and thanks for this tutorial.
Has I'm new to docker and synapse but I would like to setup the same thing using docker but I'm not finding a clean step by step tutorial on how to do this.

My goal is to set in way I could use docker swarm in future.
Any advises or links? thanks in advance
America's rats are getting desperate amid coronavirus pandemic
API can only get first 3200 tweets from a user is also a dealbreaker.