skysight-inc/HackerNews huggingface dataset:
I do not think I will be here long. It is even worse than it has been in academia.

I will share this with you, I do not think hydroxychloroquine is needed, only high dose zinc. It is looking more like lower ACE2 activity is causing the majority of issues. Since ACE2 needs zinc as a cofactor, well...

https://www.radboudumc.nl/en/nieuws/2020/radboudumc-research...

"Covid-19 enters the lungs via the ACE2 receptor. The virus binds to the receptor, which then pulls it into the lung cell where the virus can multiply. In case of a massive infection, this process makes the ACE2 receptors disappear from the outside of the cell. With that, their function also disappears."
Drive by lawsuits for the ADA are very much a thing

e.g.,:

Beyonce -https://fortune.com/2019/09/21/beyonce-lawsuit-website-ada-c...

https://tandem-interactive.com/ada-compliance-websites/
My understanding is that nobody has found signs of that in the sequenced genome. By all accounts the jump to humans appears to have been natrual.
I'm very happy to see a tool like this that can be self-hosted.

Back around 2010 there was a company called Topsy[0] who was supposed to be the "Google of Social Media". It would index Twitter tweets and Google+ posts. The idea was you could read discussions over the years and find trends that could be used for research, analytics or marketing.

Sadly, it was bought up by Apple who shut it down a year or so later. There is still a giant hole left around search for Social Media, with each of them being their own walled garden.

[0] https://en.wikipedia.org/wiki/Topsy_Labs
I've been using nannou [1] for these types of projects in rust and really loved it. Could they be interoperable?

1. https://github.com/nannou-org/nannou
I thought this is crap as usual, but no.
This is pure genius.
Your “lots of interesting articles” were what made it a political football. Before it was picked up by the right-wing propaganda network there was one obviously flawed study and some fringe non-experts promoting it to people anxious for a cure, followed by a bunch of actual experts urging caution.
Probably 1 gas station for the return trip. They had expanded gas tanks to last the whole trip.

Assuming they were infected and shedding but practiced reasonable safety precautions when they stopped, it is easy to have no potential exposures.

Potential exposure is essentially 0 if you correctly wear gloves, a mask, and keep a reasonable distance
Was foxconn given tax breaks only? Or did they also spend significant tax dollars?

Its always odd to me when subsidies are advertised as a cost, i.e. lost tax revenue. That would mean not having Foxconn come to Wisconsin at all is also a cost, i.e. lost tax revenue. And that Foxconn also cost adjacent states a ton by not moving to them either. That seems odd to phrase it that way. Subsidies are not a cost.

When I buy something at Target for 50% off, did I just cost them money? Doubtful. They're still making money. And its in Wisconsin's interest to make some money, rather than nothing.
Conway's Game of Life – Bill Gosper's Remarkable Demo
The only cons are for the activists, it takes an extreme level of privilege to see all the free stuff that people are getting showered in and think "someone should stop this". GDPR is just another reason that the EU will continue to lag behind SEA and the US in software, the exceptions are the cases extending from external markets where the product is primarily data financed by other groups. GDPR is just Europe demanding a free ride because why innovate when you can legislate.
The 9th circuit discusses this briefly at the bottom of page 7 here:

http://cdn.ca9.uscourts.gov/datastore/opinions/2018/06/07/16...

> California Courts of Appeal have interpreted this reference to mean that the Unruh Act prohibits arbitrary occupational discrimination. Sisemore v. Master Fin., Inc.,151 Cal. App. 4th 1386,1405–06 (2007); Long v. Valentino, 216 Cal. App. 3d 1287,1297 (1989).
I just came to say, I love 18F. I worked there from 2016-2018 and it's an incredible organization. If you are looking for a place to contribute to the federal government and make a difference with your technical skills, take a serious look at doing a tour of service.
U.S., Saudi Arabia, Russia Lead Record Oil Output Deal
Great video thanks for posting
Truly a great episode. Definitely recommended by me too.
While diesel fuel combustion engines produce lower levels of carbon monoxide than gasoline engines, these emissions can still generate lethal amounts of carbon monoxide given a sufficient amount of time in an enclosed space. Carbon monoxide makes up anywhere from 2% to 12% of diesel exhaust gases.

https://www.dieselinjurylaw.com/carbon-monoxide-poisoning
Both things can be true at the same time.

Whether or not the virus is human engineered or not is orthogonal to whether or not it escaped from the nearby lab.

It is known that the lab was studying these sorts of viruses.

The same lab was responsible for a SARS outbreak in the year following the big SARS outbreak.

Mistakes happen.

EDIT. I was mistaken about the specific lab that was the source of the 2004 SARS outbreak. The lab responsible for that outbreak was in Beijing.
Ahem: https://en.m.wikipedia.org/wiki/Rerum_novarum

> The richer class have many ways of shielding themselves, and stand less in need of help from the State; whereas the mass of the poor have no resources of their own to fall back upon, and must chiefly depend upon the assistance of the State. And it is for this reason that wage-earners, since they mostly belong in the mass of the needy, should be specially cared for and protected by the government.

This isn’t new!
As a practical argument I would say that GDPR has been largely a failure.

Pick 100 websites and you will get 100 different implementations.

Pick 100 users / organizations and they will have 100 different demands and expectations.

Beside a couple or so high profile cases of American companies, regular SMEs are hardly ever persecuted, even after reports.

If we don't start writing data privacy and security related laws like specifications, we will never reach a point where the industry has safe practices.
Looking very carefully and with patience one can find everything on NCBI database.
Otherwise there is a big repository of sequence here: http://www.mgc.ac.cn/DBatVir/
i'm saying the premium you mention is the additional willingness-to-pay for those equities being the best available, not something intrinsic to the underlying business. it's on top of the value of the cash flows.

in a hypothetical market with 2 relatively correlated (similar beta) stocks, one that historically returns 10% and one that returns 2% and an expectation that those returns continue in the near future, you'd put all your money on the first stock, regardless of the price and regardless of systemic conditions.

in that scenario, you'd expect to be making your most rational choice even if you overpay severely. in the case that the market crashes, you'd lose less money than the opposite scenario. the price says nothing about the value of the underlying cash flows (the fundamentals).

this is one way economic bubbles develop.
> No more articles

https://news.google.com/search?q=hydroxychloroquine
What is the class of grammar they can handle? (I mean in the sense of LALR(k), LL(k), etc.)

And is there a large (e.g. exponential) performance penalty for large lookahead?
"Foxconn has announced a giant glass dome that will house a data center"

I'm hard pressed to think of a worse place to put a data centre than under a glass dome. The moon, perhaps?
Just because it's not engineered doesn't mean it didn't come from a lab. It could be a natural virus that was collected and escaped. The original SARS escaped no less than 3 times from chinese labs following the outbreak.
Are you suggesting the virus didn't originate in Wuhan?
One day Google locked one of my gmail accounts and demanded a verified phone number in exchange for access. Luckily, that email wasn't that important. However this taught me a lesson: next time Google is going to lock my important gmail and demand an ID, W2, routing number, full address and medical records in exchange for access and then I'll have a hard choice. That day I finally put effort into setting up my own email domain.
I can't wait to give this a try!
I'm not a customer of Google nor Facebook, but they're still tracking me all over the internet.
I love Ethiopian food, but it has never seemed mainstream to me. Claiming it’s part of the shared American palate is going to need a citation.
What a strange comment.
Very naive question here. I am not an economist. I'm all for normalizing distances between haves and have nots. But why is this solution to give money? Why not universal basic housing, universal basic food, universal basic internet, etc? It seems odd to propose equalization of needs with something that is so ethereal and arbitrary and easily games as money.

If the goal is normalization, why not just wage caps instead of minimum wages?
So...evidence?

Stating it's compelling isn't evidence, just that it is an explanation that appeals to large populations of our species who are hold certain suspicions.

There is, however, a long history of animal to human transmission of diseases.

Extraordinary claims require extraordinary evidence. I have yet to see anyone provide evidence, only twitter rumors, and twitter rumors aren't even regular evidence.
Nim is the ultimate glue language. JS, python, c, c++, obj-c, even glsl... It's cool.
I don't think dailymail or nationalreivew are reputable source other than presenting a story.

There is an article on Nature one month ago on this topic:

https://www.nature.com/articles/s41591-020-0820-9

> Our analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus
This food looks delicious and I'd love to try some. It seems that they haven't "Americanized" it as much as many other ethnic restaurants - though I haven't had real Ethopian food so I don't actually know that for sure.

I wish that Americans would stop paying for shitty versions of other cultures foods. I live in a huge city with lots of people of a certain south-east Asian ethnic group. I am also married to a south-east Asian of said ethnic group. We have tried every one of the available restaurants and not a single one of them comes even close to properly approximating the food available in her home country (according to her).

In her opinion, this isn't just because of a lack of available ingredients. It is because Americans don't want authentic food. Fix your shit America because we will forever be (along with the UK) the laughing stock of the culinary world with these practices.
Agreed. The most sobering chart i've seen regarding what the fed is doing is the Caracas stock index: https://www.bloomberg.com/quote/IBVC:IND

Stocks going up doesn't indicate that the economy is fine.
Big, if true. Wouldn't one have trouble building up higher concentrations of zinc in the cells without ionophores though?
Wuhan.
Why would genetic engineering (or lack there of) be a necessary sign here? The Wuhan lab regularly collected and studied various naturally occurring coronaviruses from all over China. It is perfectly possible that a collected sample from nature might have been leaked by accident.
https://en.m.wikipedia.org/wiki/Liberation_theology#Towards_...
typo, updated.
Well said, you can't buy smartphones and videogames with food coupons.
I'm astounded every time I come back to these videos, and I know HN will appreciate them. Nowhere else have I seen this level of Life hacking.

If you know a way to access the software or patterns used in this demo, please let me know.

Youtube description:

"Bill Gosper's LIFE and MACSYMA presentation from November 4th, 2007 at the Computer History Museum during VCF 10."

Part 1: https://www.youtube.com/watch?v=BpgA2oCQj9o

Part 2: https://www.youtube.com/watch?v=PFxEyoujzxw

Part 3: https://www.youtube.com/watch?v=ppnadmuDRIs

Part 4: https://www.youtube.com/watch?v=5wmg7xZLtjU

Part 5: https://www.youtube.com/watch?v=d_AXix3ALeM

Part 6: https://www.youtube.com/watch?v=Cplgw4h_zgk

Bill Gosper: https://en.wikipedia.org/wiki/Bill_Gosper

Hashlife: https://en.wikipedia.org/wiki/Hashlife
Thanks for the link. You guessed well, it is a fun read.

Its quite satisfying you get the property from the rotational aspect of the QM.
> I think it is overwhelmingly likely

Why are you so sure it is overwhelmingly likely?

> I think it's probably just a coincidence that there's a virology lab there

Only because you believe it to be purely coincidental of a virology lab being next to the outbreak source location?

I am entirely up for accepting this viewpoint. But, the lack of evidence to suggest an actual source location coupled with the (CCP sourced and pushed narrative of) "overwhelming evidence" that raw bat consumption at the market started it leads me to lean towards a more logical conclusion of a simple lab escape.

Am I being illogical in thinking that a pathogen escape from a virology lab (built in 2017, btw) in the same locale is more likely than a random zoonotic transfer of raw bat consumption (a practice likely being done at the same market for a considerable more amount of time)?

EDIT: change "less likely" to "more likely"
The big lesson from South Korea's coronavirus response
LOL everyone in China 'disappear' when they decide to not post on social media for X amount of days. Of course you never hear story that they're 'found' by posting or doing something again - despite the fact that they almost always do.
The obvious solution to spam/scams are micropayments.

When you send an email, you attach a micropayment (say 1 cent's worth). When the recipient opens the email, you get your 1 cent back.

This would make mass spam unfeasible while still allowing companies with legit bulk email needs keep sending email, since they would get most of their money back.

It would even create an industry for people to be the payment middleman where they front you the cash for your bulk emailing and then assume the risk and keep the difference as profit.
Not sure why this is downvoted. It is not Indonesia as the previous child (now deleted) alluded to — the easy tell is the distinct lack of Hijabs visible (which are ubiquitous in the largest Muslim country in the world).
According to the deleted research center job and notice postings in November and December it allegedly originated in Hunan among bats, and they collected it and brought it back to the Wuhan lab.
Tucker Carlson did a piece talking about how the bats that this jumped from do not live within ~900km of Wuhan, but that the lab in Wuhan did testing on the bats that they imported. It definitely seems plausible they were doing research on these bats, and that due to some improper controls it jumped over to a human working in the lab and that was our patient 0.

It definitely seems feasible to me that it could have "come out of a lab" while still being entirely natural in origin and without any ill intent on the Chinese part.

I'm not endorsing this as true, I don't know if it's true or not, but I did find it interesting and worthy of additional research.
A Politicized WHO
As the coronavirus disrupts food supply chains, who will feed China?
People can draw their own conclusions. That is what is nice about solid evidence. I will make two notes:

1. Bats can transmit viruses to humans independent of wet markets and research activities and these villagers do travel to cities;

2. This particular research was funded jointly by USA, China and Singapore to monitor possible recurrence of SARS like virus.
Furthermore, gain-of-function research doesn't have to be by genetic engineering. The controversial experiment of a few years back which I vaguely remember was more like natural selection.
No & yes, respectively.

> In 2018, the Walker administration shifted up to $90 million in local road funding to road work related to the Foxconn factory.
For our software friends wondering what’s so special about processors: they are the most parallel state machines designs out there. Most other state machines have fairly well defined and narrow inputs and outputs. For performance reasons, a cpu pipeline is the biggest collection of state machines interacting with each other directly.

Therefore most formal methods blow up on cpu designs and random coverage is really hard to define and even harder to reach.
It could be lots of things. The focus on a possible escape from containment as the source seems odd given that - among other more likely causes - bat guano is also widely used as fertilizer, and bats, like humans, shed coronaviruses in their feces. Except that where we do so only occasionally and only when actively infected, bats' generally higher viral load and the high intraspecific transmissibility of a lot of these viruses means they do it much more frequently.
So your example is a website that does violate the ADA. I understand that ADA compliance is hard for websites... that's not a legal issue so much as a technical issue. We do treat support for the blind, et al as an afterthought. So is your complaint here that the ADA is being enforced? Like we should just get rid of the ADA because people aren't complying? Or are you upset the ADA doesn't say: please make your best effort? Better support for the disabled in our front end frameworks would be awesome.. It is too bad there isn't more focus on it.
Who knows the amount of jokes being written now given the current political landscape...
Qualified and means-tested solutions impose what we feel others need upon them. Yet, if you just provided money, they could fill the gaps they know they need and markets would emerge to satisfy those needs. For example, one may see a "smart phone" as not a necessity, but, for many it's the only computer they have and the connection to their economic world. Who are we to say that a smart phone isn't a necessity? To a worker who is on their feet all day, a very expensive pair of boots that will last years may also be a necessity. Who are we to know people's needs?
How to Live on a Narrowboat
shaders. opengl does recompile them but all while your os executable is running. its a very useful and easy thing to set up live shader reloading. much quicker cycles to experiment.
It's just as much China's (or anyone else's in the interest of science) to prove the lab had zero correlation to this incident. If only to appease a crowd.
Why its a good time to build a startup
That doesn't mean it didn't come from a lab though. "Coming from a lab" does not = man made. If they were doing research on the bats in this lab, looking to identify potential scary viruses to be ready, it is entirely possible the virus jumped from bat to researcher there and that was our patient 0.
Something similar to this that works better IMO is Online Town, which was posted yesterday on HN: https://hn.town.siempre.io/

https://news.ycombinator.com/item?id=22818300

A 3d version of this concept is well executed by Mozilla Hubs, but the lack of echo cancellation makes headphones a necessity when using Hubs which is a downside.
Dr Shi Zhengli was working on bat Coronavirus research in the US and we closed the program down in the US in 2014 for being too dangerous. She returned to China to continue her research in Wuhan.

It is neither fiction, nor dangerous to speculate that this outbreak started at the Wuhan lab.

It may not have been engineered.

However, the bats are brought to Wuhan lab from hundreds of miles away to be studied. It is also very possible that a bat carrying the natural virus being studied at the lab escapes or infected a person.
This paper is only about engineering a virus using a common backbone virus as a starting point.

That does not mean the virus could not be derived within a lab using recombination methods in other animals and sourcing the starting novel virus from bats. In fact, this type of research was the exact research being done at the Wuhan Virology lab.
Not quite the same thing but this well-regarded nonprofit gives cash instead of alternatives, and their about page talks a bit (with some citations for you to read more) about why this is more effective than alternatives:
https://www.givedirectly.org/about/
Iron Kaleidoscope: LLVM Tutorial in Rust
Lots of vlogs about this:

https://www.youtube.com/channel/UC6SNxiLzSlh8e0yjndE9o_A/vid...

https://www.youtube.com/watch?v=6sbb9qm-pqw
I don't see any evidence to suggest the virus was engineered or released deliberately. why would you deliberately release a bioweapon in a densely populated part of your own country? doesn't make sense.

the lab in wuhan is not just any virology lab though; it's one of only two biosafety level 4 labs in all of china and samples of similar coronaviruses are held and studied there. it may very well be a coincidence; improbable things happen all the time in a world of ~8 billion people. it would be a pretty big one though.
Also the only lab that handles this stuff in Wuhan is less than a couple hundred meters from the wet market that Chinese authorities claimed was the epicenter.

I'd believe this is a story of grave incompetence, and brazen managerial failure at a biolab. The intern gets bled on, bitten, or just breathed on by the test bat, gets a bit sick but comes into work anyway. After it seems to pass, she heads down to the market on the way home, and spreads the disease to one of the live animals, including humans, in the vicinity.

Boom, outbreak.

Could be as simple as that, with it being a pretty tenacious virus.

The proven conspiracy follows, when authorities up to the top sought to cover up this embarrassment, then to make sure that the damage was global so that they wouldn't be at a relative disadvantage, and could maybe start claiming that it came from somewhere else (as they are now doing).
I agree with all of that, honestly. What I think is going to change is the belief by the company that WFH is undesirable. Most companies, even those that allow remote work, would prefer that everyone be in the office. There are tons of companies (my own included) that discouraged WFH policies, but given that we've been 100% remote for the last 3-4 weeks and the sky hasn't fallen, I can see a lot of companies (and a lot of employees!) warming up to the idea that WFH is not only palatable, but even a good idea and a nice perk for attracting new employees. My company would never have allowed this many people to WFH in a pre-COVID world, but I can definitely see that changing in the future.

Yes, there are very good reasons that people can and should work in an office. Absolutely. I 100% agree with you. But I think that businesses will start to realize that there are just as good alternatives to a lot of those reasons -- and especially if, as I mentioned, someone can crack the virtual social problem. If it's as easy to hop on a video call and sort something out (virtual whiteboarding?!) in a minute or two, then that's just as, if not more, efficient than being in an office. If we can virtually socialize similarly to how we do in an office, have water cooler moments similarly, hold meetings similarly... then a lot of those reasons fall away.

To be clear, I'm not saying that businesses will move to 100% remote. That's obviously not going to happen no matter what for 99% of companies. But I think the idea of WFH is going to become much, much, much more palatable and desirable to both companies and employees out of this.
Marco Polo video messaging app
i think his point isnt so much about structural integrity as it is with volume and required effort to get that structrual integrity

a pyriamid is a huge srtucture with tiny tiny passages that are of use to almost no one, which took massive amounts of work and time to accomplish

whereas a cathedral constructed mostly of arches made of less than 100th or a 1000th of the material could scale to the size of a pyramid yet internally be mostly air

taken further, a geodisic dome could scale even further and easily encolse both, with even less materials

so what he is saying is, architecture matters in relation to effort, scalability and also structural integrity