skysight-inc/HackerNews huggingface dataset:
You need these high concentrations if you apply them too late. HCQ needs a few weeks to settle in the cells.

What I want to see are studies applying HCQ before the infection (that's what the Chinese measured, Lupus patients being immune), are at least when they were tested positive and sent home. Not when the shit already hit the fan, and the mucus is in the lungs causing bacterial infections all over. Because then it's too late already.
We've changed the title in accordance with the site guidelines.

Submitted title was 'Boston study finds 35% of homeless are Covid+ (via PCR)'
It's definitely a niche, most people buying $1000 phones are probably driving newer cars.

However I think use cases like air travel or just hanging out at home with a low battery are less rare. These can be partially mitigated w/ wireless charging, but when I use a wireless battery pack on a flight my phone and tablet don't do a great job actually staying in place, and necessities lowering the tray which is annoying
Thanks!

> You won't find this (that I know of) with earbud types.

Ah, yeah, that's why I hadn't seen this. Can't really put headphones like these in my back pocket!
The study is way underpowered (too small a sample). Based on the raw numbers, the HCQ group had less deaths and less ICU admissions, but the numbers we're talking about are 3 vs. 4 deaths and 16 vs. 21 ICU admissions (group sizes were different).

These numbers simply aren't enough to make a determination one way or the other. On mortality, the 95% confidence interval allows for a range of HCQ reducing death rates by 87% up to it increasing death rates by 2.9x.
"Perfection is achieved, not when there is nothing more to add, but when there is nothing left to take away."

Antoine de Saint-Exupery
To be fair, you have these latent single points of failures even in the most resilient distributed systems.

Such as S3. The bucket names are globally unique, which means that their source of truth is in a single location. (Virginia, IIRC.)

Now... a small thought exercise. If I wanted to take down a Cloudflare datacenter and I had access to a few suitably careless remote hands, I'd take out the power supplies to the core routers, and while the external network is out of commission, power down the racks where they have their PXE servers. That should keep anything, within the DC, from being unable to recover on its own.
Cf Robert Putnam's paper on Diversity. No one likes to look too long upon pretty lies.

https://www.econlib.org/archives/2017/06/trust_and_diver.htm...
>lack of headphone jack

My significant other got some bluetooth for xmas. (A nice bose since she is wildly anti apple, im not totally clear on why) She was into them for about a month.

With cabled audio it is sort of unavoidable to miss that never having to charge, pair, unpair, removing phone pairing history (example rental car retaining contact info), just plugging in is so clean, reliable. Honestly in the case of BT vs 3.5 jack i believe we invented in reverse order.

She has since stopped using the >$100 Bose and prefers a 20 sony earbud where one of the two ear buds is actually totally smashed (i drove over it, sadly. Shes a total catch.

So the missing audio jack is my only barrier to new iphone SE entry. I wonder whether anyone has considered some pcb+3d printing a slim fitting adapter which might extend the length of a phone but then provide the existing port and add a 3.5. In other words Is there any attempt at integrating the usb c Or lightning to 3.5 adapter into a clean little clip on / case thing.

Re rental car Bluetooth cleanup issues https://www.consumer.ftc.gov/blog/2016/08/what-your-phone-te...

And to be clear im not anti bluetooth at all. It just seems to be a not yet rightly set up system for security and convenience, naturally.
I love it! i still have the old iphone 5se
I want to buy this one!
I don't really get the hate for the lack of a headphone jack tbh. Have people complaining about this ever really given good bluetooth headphones a chance?
My Beats Solo 3 have fantastic battery life, i can switch between devices with a click of a button (in the case of the Bose QC35 even be connected to two devices at the same time, listening to music on the laptop while being able to receive phone calls on the phone) and the sound quality is absolutely fine. Sure, an audiophile DAC with high end headphones will have better sound quality, but do you really need that on a phone?
New Earth-sized planet found in habitable sweet-spot orbit around a distant star
I think it’s fair to assume most people are mostly interested in statistics that give an indication of the likelihood of dying from a Covid-19 infection, which means you would have to look at the infection mortality rate and not the CFR. So in that sense I think it actually would be somewhat comforting if if it turns out many more people have already been infected than previously assumed. But just to be clear, I don’t want to pretend anyone can reliably claim this considering we still don’t have enough data to create models that can be used to approximate infection rates.
This could be correlation. People taking HCQ have autoimmune problems like lupus, and therefore would be more cautious and practicing social distancing earlier, therefore not getting infected in the first place. It also might be true that people who are agoraphobic shut ins are not contracting covid. But that doesn't tell us much about how covid interacts with agoraphobia.
Instagram rival VSCO lays off 30% of staff to reduce reliance on outside capital
DIY Face Shield Made Out of Laptop Cover
To me, no headphone/earphone experience has ever been better than my AirPods. I have both the normal and Pro versions. They fit magnificently. No cable means nothing ever pulls on my ears, which over time can be painful and irritating. I can listen in bed on my back, on my sides, etc. It's not a big deal to take them out and just stick them in a pocket. And I know people complain about how easy they are to lose, but anecdotally, I have lost wired bluetooth earbuds in the past, but never lost an AirPod since I've gotten my first pair in early 2017.
Worse, with late fees. You can still get evicted legally as well, it's just that they can't remove you.
The WHO and China: Dereliction of Duty
Biden has "a real chance to be one of the biggest game changers in the history of medicine". Damn, I had better vote for that guy!
You may be right, but I don't see it. I have been reading since about 2005 and I don't recall seeing a strong stance against outsourcing at any point in that time. It would have struck me as surprising if I had, since they are broadly in favor of free trade, and outsourcing clearly fits the bill (even if you put it in scare quotes).

I don't really disagree with you about any of the points you're making, which means I often or usually don't agree with the Economist on these points, I just think it's a weird critique of the Economist to accuse them of being globalist, free trade, neoliberals; to me it's like, yeah, they are the Economist... It seems like accusing Jacobin of being socialist.

Maybe this change happened before 2005? I'd be interested in seeing some receipts. Are there some anti-outsourcing articles from way back that I've missed?
Yes, for all zero of them.
https://basicincome.ycr.org/
I've wondered if a five-a-day downvote limit would benefit HN.
You can make educated guesses based on age, preexisting conditions, etc.
The amount of effort for a compiler to process optimally all 72 variations of "read/write a signed/unsigned 2/4/8-byte big/little-endian value from an address that is aligned on a 1/2/4/8-byte boundary" would be less than the amount of effort required to generate efficient machine code for all the ways that user code might attempt to perform such an operation in portable fashion. Such operations would have platform-independent meaning, and all implementations could implement them in conforming fashion by simply including a portable library, but on many platforms performance could be enormously improved by exploiting knowledge of the target architecture. Having such functions/intrinsics in the Standard would eliminate the need for programmers to choose between portability and performance, by making it easy for a compiler to process portable code efficiently.
Not to mention the social stigma if the 1st attempt goes wrong, potentially reducing people's inclination to get the vaccine.
Kitchen counters, too.
Maybe we run in different circles but the two main sides I've seen are "This drug is a miracle cure" and "Maybe let's wait for some evidence". If the first side flipped to "This drug is terrible" then the other side would still be saying "Maybe let's wait for some evidence". I haven't seen very many people actively hoping the drug doesn't work just to spite the president.

For some issues there's plenty of partisan hackery to go around, but in this instance there is clearly one person to blame for turning this into a partisan issue. Politicians should not be offering their opinions on drug efficacy, full stop.
Isn’t this a trivial feature for Google to add to all Apps accounts? I can’t imagine the logic for picking a meeting time being that complex and “next available” is likely the right answer for most people any way.

Shared calendars could easily be done by them as well for the entire GSuite ecosystem with one off “approve picking a spot” on a per meeting basis.
Compare to Powershell, which also works with structured objects.
The CFR is 21% [0]. We're already assuming the IFR is 10x lower.

[0] https://www.worldometers.info/coronavirus/
I agree that downvoting should be mainly for either a mean post, a post that adds nothing ("me too" or "lol"), or a poor argument like an ad hominem or incorrect premises. Instead it's used for feelings, as if we could collectively vote on reality. Maybe dang/mods could put some ever-present reminder someplace in the comment 'reply' page.
One way we try to solve this problem in our paid product is by prioritizing more urgent meetings (marked ASAP in our tool) and dynamically moving flexible ones (marked "This Week / Next Week / etc.") around if possible to free up space. If the meeting is scheduled manually via Outlook/GCal, we assume it is high priority and don't move it. We experimented with more complicated priority systems but ultimately that required too much work from the user
An average age of 59 on the Diamond Princess (1.8% CFR) is not representative of the general population. This is a substantially more at-risk group.

Germany and Singapore are also missing many infections. A recent serological study in Germany actually argued for 0.4%.

You are correct that IFR is skewed by who the population is and what interventions are done. But then again, so is the often cited flu benchmark (where we have targeted vaccinations of at-risk groups).

(And age is a huge thing to be aware of skewing the data. e.g. the pediatric IFR from covid is on the order of seasonal flu)
I have a cellular Apple Watch! But Apple doesn't let Spotify sync music to it (or stream via the CELLULAR), so I can't listen to anything unless I'm near my phone.

Imagine my surprise when I got an Apple Watch with cellular specifically to avoid having to take my phone with me. Absolutely absurd - and it's obvious why - they want you to use Apple Music. I refuse to be forced into using a piece of software. And before someone comes back with the inevitable "well you should have researched it":

1) I never thought such a simple and obvious concept would be absent from the Apple Watch, and
2) I use the Watch for the utility of fitness tracking, and that far outweighed the inconvenience of having to continue bringing my phone with me everywhere. I'm not a big runner anyway, usually mountain biking, and my phone is in my backpack or mounted to my handlebars.

Bottom line is it's ridiculous.

EDIT: I did some research on this again and it appears that Apple actually does allow developers to stream and store data from the watch, and that it's Spotify who have yet to release an update for their WatchOS app that provides that functionality. Interesting turn of events; at least I know it's theoretically possible and not gated by Apple.
Russian Ponzi consumes 8.5% of all Ethereum daily gas
Just because you dont see a need for it, does not mean there is not a need for it.
Edit for definitional clarity: My use of the term socialism here is exactly equivalent here to the term "systems that enable wealth redistribution through legislation" no more, no less. Im not commenting on anything like the ownership of the means of production in society or anything like that.

It seems like the whole world is chomping at the bit to enact more socialism but do you think it's homeless people and cashiers that are defining the rules of the system and legislation? Of course not, it's lawyers and politicians. So are you really naive enough to believe that they write perfectly fair legislation that doesn't favor their interests at all?

Friedrich Hayek nailed this on the head almost 100 years ago. The problem with socialism isn't that its not an admirable goal, it's that even if you want it, by nature you aren't going to get the version of it that you wanted, you are going to get the version of it the a bunch of politically connected insiders design and while they may not be totally self serving, they are usually going to figure out how to be on the winning end of the game.

Crass said it well:
"But no one ever changed the church by pulling down a steeple

And you'll never change the system by bombing number ten

Systems just aren't made of bricks they're mostly made of people"

The systems you get are the ones the people who design them make. Thinking otherwise is foolish. The people who should be the most scared of redistribution systems like this are the ones who want to look out for the interests of the little guys.
> The stark contrast is in reality it is the President that is trying to profit

Trump's stake in hydroxychloroquine (which is a generic, and a bit safer than the chloroquine mentioned) is held via a trust and a mutual fund (so no direct investment) and is valued at less than $1,305, basically pointless.

https://www.businessinsider.com/trump-small-financial-ties-h...

Edit: Love how I'm getting downvoted for pointing out facts.
That type of work is too infrequent for most companies to justify hiring a dedicated developer.

You should work for a system integrator if you want to do that kind of work with regularity. The integrator contracts you out to those companies as needed, and you develop a niche and maybe customers start asking for you by name. In the best cases the integrator is your employer and offers full benefits, as well as absorbing the costs of downtime.

That business model can also be abusive for obvious reasons. I can recommend a good company if you're interested.
I still have a Radio Shack Battery Club card with only one more punch needed. Maybe if I run into him... nah, he'll insist I have to give him my name and address.
Good bluetooth headphones cost hundreds of dollars, good wired headphones can be < $100. And I never have to charge wired headphones - I can always rely on them to just work.
Which medical school is that? Caribbean one?
> The first iPhone SE was a hit with many customers who loved its unique combination of small size, high-end performance and affordable price; the new second-generation iPhone SE builds on that great idea and improves on it in every way.

Customers loved how it was both small and powerful, so we've improved it by making it much larger...[1]

OK, I realise they mean "small compared to the ridiculous size of other phones" here, but I still feel like they've missed the point. They could have had the only truly small and powerful phone on the market in 2020, on any OS! No competitors. They could have even kept the exact same old SE size and had an even bigger screen (5") if they went edge-to-edge.

[1] https://www.apple.com/iphone/compare/?device1=iphoneSE&devic...
Recipe to Greatly Layered Architecture
Why is the stockpiling function so centralized? How much supply does each individual hospital/medical center have on hand in reserve during the normal course of business?
If a theory's predictions are 100% consistent with experiment, then it becomes the bottom for all practical purposes, since all we have is practical knowledge. Saying we can't prove it's the bottom would mean as much as saying we can't prove the universe is on the back of a stack of giant tortoises. Technically true, but of no practical importance.

Of course, if a theory doesn't agree 100% with reality, then there's more to find in a practical sense, in which case "not having reached the bottom" is true by definition.
That’s not scalable. But maybe a 1/N probability of being required to do so, for reasonable N.

(Edit: something like slashdots categories could work but you’d need some incentive to be truthful rather than trust them to separate a “troll” from a “disagree”.)

Plus, if anything, I’d say it’s more common for there to be a bias against downvoting relative to upvoting.
The "audiophiles" insisting on the need for 3.5mm analog output have always been strangely silent on the fact that they are tacitly accepting that whatever DAC is built into the phone is up to their standards.

That said, small but very decent DACs have been around for a while. There's one smaller than your pinky nail inside the lightning-to-3.5mm adapter included with newer iPhones.

There are plenty of good reasons to want a 3.5mm headphone jack on a phone. But audio quality is not one of them.
The concept of course was Jerry Weinberg's in The Psychology of Computer Programming (1971). I always felt like that book should have had a different title. Maybe "Computer Programming as a Human Activity", which is what he said it was about in the preface: http://wiki.c2.com/?ThePsychologyOfComputerProgramming. The concepts of the book are more social than psychological, as I recall. Even "egoless programming", which is psychology in the sense of looking at how we identify with our ideas, is also about interactions on teams.
It’s like the reverse story of Jonathon Nelson from Hackers/Founders who was a paramedic before becoming a CEO.
Export your Figma designs to SwiftUI
CSF leaks/hypotension are also potentially implicated in frontotemporal dementia: https://journals.lww.com/neurotodayonline/Fulltext/2002/0900...
It's strictly a decrease in functionality. My phone, with a headphone jack, also supports bluetooth, if I wanted to use it. What do I gain by losing the headphone jack?
> rather than under medical advice

Correct, which is why I used the expression "ill advised". The advice in this case being that of a doctor.
Last time I saw something like this, it was from someone's browser extension using pastebin as a backend. Wonder if there are anything similar things for this.
Anaesthesiologist here.

I did EM for 6 months and hated it. This is because it just doesn't suit my personality.

To be good at EM you need to be:
- Comfortable with being a kinda bad at everything and great at nothing
- Comfortable with large amounts of uncertainty and risk and having to make decisions anyway
- Being abused by drunk/mentally ill patients constantly
- Being patronized by medical colleagues in other specialties
If I start with God, any conclusion I will care to make will be true.
How big is Amazon compared to FNAC/Darty, Cdiscount and co? Personally I have never ordered anything there because

- when it comes to books, they are not cheaper than at my local bookshop, in fact they are often more expensive.

- for home appliances, I always prefer buying things sold directly by the platform and not a third party seller or dropshiper, unless it's something used, but then I use ebay.

- I don't care about one day delivery, personally, I'm fine with waiting.

- For some reason, I hate the UI I find confusing and way too busy. Even that monstrosity that is Cdiscount UI feels easier to browse.

So what are the advantages of using Amazon in France compared to other platforms? cheaper delivery fees? better customer service? or having the convenience to be able to buy anything at the same place?
We'll find a treatment for coronavirus – drug companies will decide who gets it
Contracts... for dog walking? Here is the contract: "I give you a $20 bill and you walk the dog, deal? Let's shake on it."

That's how it worked for dog walking and lawn work when I was doing it as a teenager. No lawyers, no paperwork, no signatures, nothing needed to get notarized. No bullshit. KISS principle in action.
Car size have steadily increased up to the early 2010s [1] and I haven't noticed a stop to this trend, especially when including the market movements towards car-like small SUVs.

Availability of smaller cars keeps going down (Honda Fit dropped in Canada, Toyota Prius C gone, etc.)

[1]: https://www.teoalida.com/cardatabase/images/Car-Classes.png
“Up to 90% of the highest salaries available”? I’ve worked on one of these and you’re more likely to get 60-70% of what you could otherwise be earning in some mediocre fintech company, let alone top salaries. Which is a much harder sell for most people.
This will tend to skew with how high up the stack you've spent your career.

Zynq will probably be familiar to anyone who has been dealing with SOC and FPGAs at all recently.
And all this time the presence of EasyAntiCheat has hindered how much I play the game; DBD would otherwise run fine under Wine/Proton yet because of EAC I have to load up my windows VM, switch my GPU from Linux to Windows, etc.

But essentially any anti cheat can be defeated because it's still all client side validation. The only effective anti cheat is detecting player patterns which typically ends up needing human reviewers (see CSGO Overwatch system).
I agree with both of you.

I'm hoping to hit a chunk of that "middle option" you spoke of with PhotoStructure (details in my profile). I'm building sharing next, so hopefully that aspect will be addressed as well. Hosting the software yourself addresses privacy concerns. The beta is being offered for free in exchange for feedback.
I don't know about everyone else but I sometimes use a 3.5mm to RCA cable to play music from the phone through a stereo.
Yes you need it. I have a great pair of BT headphones, but I also have a great pair of wired headphones. There are times when I would prefer to use the wired ones, not the least of which is when walking through a busy city where BT likes to cut out from all the interference.

Our Mini-Van also doesn't have BT. I have to use my USB-C adapter which means I can't charge and listen at the same time. Very inconvenient on long trips when I'm also using the phone for navigation.
IPv6 improves this situation (now). At first, ipv6 was actually a lot worse, since the back 1/2 of your address was your MAC address, allowing your device to be tracked around the internet no matter where it went.

People quickly realized this flaw, and updated the standard so that basically your client gets to pick the second 1/2 of your address now. And the nice thing is, most major platforms will actually run multiple addresses in parallel, allowing new connections to use a new address while old connections keep using the old one.

So while ipv4 adds some protection by having multiple clients behind the firewall, ipv6 actually makes it better by looking like even more clients behind the firewall.

Combined with a browser that blocks fingerprinting you get slightly better privacy with ipv6.
Connecting Talent to Startups in the Midwest
> have fantastic battery life

But still less than a batter life of a phone. Running out of juice on them after a while become like a constant self-inflicting anxiety attack, with semi permanent jumps between "Should I plug them now in case I have to have it later" and "I like this song/track/mix, I will listen to it". IMHO, YMMV