skysight-inc/HackerNews huggingface dataset:
I posted and deleted a few comments. I don't know what to make of this and it's getting controversial. If it could be helpful, I'd love to improve it. I just don't know where it fits in ongoing discussions by prominent researchers on analysis of strains and types.

Three things that jump out at me:

a) You'll get more credibility from having a thorough lit review than from listing credentials. Linking to magazine articles from journalists on genetic variations, when there's academic research to cite, is a little bewildering.

b) You don't identify something harmless by just testing asymptomatics. This is counterintuitive, but a great example of the Wason selection task:

https://en.wikipedia.org/wiki/Wason_selection_task

You would probably want to survey the rate of variants in asymptomatics in a certain community, then compare that with the rate of variants in fatal cases in the same community to look for significant differences (and be fully prepared not to find any significant differences beyond chance, a real and likely possibility).

c) I'm still not sure what the author is specifically recommending we do next. Researchers are looking for functional variants, we don't have one to distribute yet, so we should do more sequencing. Ok, great. From what populations? How many geographic areas? Where do we get the samples? There are bottlenecks in sample collection, how do we overcome those? Given (b), how can we get more samples from fatal cases, to compare virulence to those in the general population? Task overloaded hospitals to send us additional samples from dying patients? Is there another way we can get this info?

I don't want to dismiss this out of hand, this might be a good area for additional focused research. I do think there are some key unanswered questions though, and currently a worrying disconnect with the current state of research on variants.

EDIT: Daniel, I know you're going through the comments here, and some of them have gotten pretty harsh, sorry for that. I genuinely hope you're on to something, and are able to continue to refine the post into a more robust and specific proposal using all this feedback, despite the tenor of some of the comments. That's really the best case for all of us, so good luck.
Just a note, no evidence of how much immunity yet. We are hoping that is the case but there are also a few loose stories of people getting covid a 2nd time. We should know more in a few weeks to a month...
Looks really nice, thanks for sharing!

For me, it is though more like "a dynamic table of contents" (at least, I would use it in that way).
Inverting a binary tree is actually something that weak candidates seem to find a way to cheat on though.

Same thing with Fizzbuzz, so it was an artificial example in my post.

The best thing for us seems to be relatively simple coding questions that are domain specific problems.

My go-to the last year or so has been an interview like this:

1) Give a demo of the product

2) Explain a problem the product has/had to solve

3) Go over the entities/objects involved in the problem

4) Present this as a simplified whiteboard problem

5) Candidate needs to write some code on the board to solve
the issue (Typical solutions < 20 lines of code)

6) Discuss scalability of the solution

7) Discuss alternate ways to refactor the larger code base to avoid having to write the algorithm that was written on the whiteboard at all

The process of having to take a problem that comes from a specific product & translate that into code seems to catch the weak candidates that cheated on the online coding tests and bluffed the recruiter nearly every time.

This is as opposed to places like Google that just constantly try to ramp up the difficulty of the non real-world coding questions they're asking the interviewee.
From the article:
"The first is that it overlooks the negative impacts on consumer sentiment and spending, which are likely to persist for many months, if not years. "

Yeah, right. Citation needed. My to-buy list of pent-up demands grows longer by the hour.
Pretty cool! I suggest adding a github link to https://github.com/gera2ld/markmap-lib in the about page and homepage.
I do a similar thing where I keep a list of things I'd like to do in a list in a markdown file. I put subtasks on them, check those off, and eventually, when the product is done, it gets checked as done. This gives a great sense of accomplishment.

Choosing what to do is a challenge for me, so I created a task chooser for when you have trouble deciding what to do next:
https://github.com/RobKohr/weighted-task-chooser

And you can assign weights to the different things. I usually run it a couple times until it tells me something I feel like doing.
Simple exposure is not enough to become immune. You need a significant infection which triggers a strong immune system response to build long term immunity. Thus in the initial stages of an outbreak you can basically ignore people that became infected weeks ago, had a significant infection, and are now immune due to the exponential growth curve.

It’s only after the rate of infection stayed the same or falls for a month+ that you need to adjust for such people.
> your response hasn't offered anything terribly constructive to the conversation

because this hiring thing is the ultimate dead horse of HN. Every single comment here is a rehash of something that has been said a million times.

Here is the one from last week

https://news.ycombinator.com/item?id=22739605

exact same comments.
Show HN: Multi-Zone Cluster Management at Wayfair with Kubernetes
It doesn't really work both ways. Angry mobs looking for food don't need guns to cause problems for peaceful people. Peaceful people do need guns to protect themselves from angry mobs looking for food.
Are those jobs in specific industries? Like financial tech jobs.
You don't even have to click a second time to select part of the URL. You simply click and drag at the same time. It's ideal for everyone.
I would like Firefox to be my main browser again but a couple of times I've run into the situation where an uncaught JavaScript error logged in Firefox's console doesn't give me any useful information as compared to Chromium. I wish I had a reproduction instead of just ragequitting but I'm sure it's a known issue that exists in their bug tracker somewhere.
a lot of hobby is much more expensive than that...
I live in MA and got very sick on Feb 26, then had a horrible cold. My wife is a doctor, and she thought I just had one of the many things going around.

I asked her if it was COVID-19 and she looked at the CDC's web site and said she didn't think so. Then a week later she flew out of Logan to spend a weekend in LA. I also went skiing in New Hampshire twice, and went to two networking events!

Throughout March I had symptoms that I never had in my life... I couldn't get a test! The symptoms went away after 4 weeks.

Did I have it? I have no idea, but if I got it, it most likely came from her or my kids, who all felt kinda wonky in mid February. My wife had a very bad headache two weeks before I got sick.
A look into 5 health startups tackling Covid-19
Officials likely get told about many potential crises, but only a small percentage of those pan out. Can we really hold officials accountable for when the crisis actually happens?

If we locked down society or accepted draconian measures at every single instance of a possible crisis, we would always be living in crisis because there are always potential crisis of some kind that could happen soon.
It's daft wrong-headed prescriptivism contrary to all common sense and usage. It just screams "I don't care about actual language, just silly pedantry".
Definitely not an expert, but I think it means you have a gene which causes eventual production of a prion. I.e., you produce proteins which have the potential to misfold; eventually this happens and prion disease begins.
If covid-19 is much less harmful than we originally thought, why were, and still are, medical experts proposing such draconian measures without a clear understanding of the true threat? Dr. Fauci, advisor to the president, proposed the other day that no one should ever shake hands again, in order to prevent spread. It is bizarre.

Even when the disease first started to spread, there were people making these same points. In fact, most people thought the disease was no worse than a bad flu or cold, hence the difficulty to institute lockdown type measures in the first place. This is certainly not going to build trust in institutional expertise on these matters. So, once the medical experts are actually right, then they'll be ineffective at persuading people.
> 1500$ display

> (I) THE PRODUCTS ARE NOT CONSUMER PRODUCTS INTENDED FOR PERSONAL, FAMILY OR HOUSEHOLD PURPOSES; AND
(II) PURCHASER IS PURCHASING THE PRODUCTS FOR COMMERCIAL USE AND/OR IN A BUSINESS CAPACITY. ORDERS PLACED BY CONSUMERS WILL NOT BE ACCEPTED.

> 500$ driver board with the same terms

> E Ink’s NDA prevents me from sharing the source code

It amazes me every single time I think about it: Why is this company working so hard to keep their products away from the public?

Additionally, how did they convince them they're not a consumer?

My mode of acquiring e-ink displays is looking for e-reader replacement parts and data sheets online. Never interacting with the e-ink company isn't only easier (please stop screaming at me that I suck if I'm a consumer, thanks), but a lot cheaper. Haven't found a knock-off for the 31" screen yet, unfortunately, that would be quite cool.
with a kalman filter the model always stays the same and is used to pick which sensor is reporting most accurately. changing the model would change everything, maybe that's why changing your worldview has such an impact on the way you "see" things.
The out-of-the-box setup on Fedora $Beta is probably the best Wayland environment that exists right now.
or both!?
Theoretical one-way latency on PCIe 3.0 ×1 for a 256-byte packet is < 0.5µs. A single register write should be < 0.1µs.
Have you paid any attention to the charts? Even if the numbers aren't truthful they can't be that far from the truth or the discrepancy would be much more obvious than it is. Just take a look at this [0]! And this despite being the first to be hit, and having hundreds of millions of people living in densely packed cities!

[0] https://www.worldometers.info/coronavirus/worldwide-graphs/#...
I was engaging with the grandparent post about "the best America's got," which is an interesting topic generally, but also specifically in terms of public health. And then I corrected your statement it’s silly to think one city is better than another on some objective scale by naming a number of very reasonable - and I think, important rather than silly - objective scales by which a city can be measured.

I mean, if you don't think a city's economic output is an important objective measure, congratulations on never having lived in an area with a serious economic contraction (or read about one, apparently). If you don't think a city's rate of cholera cases (to use a classic example) or, more to the point, COVID 19 cases, is important, I don't even...

(I wouldn't want to live in NYC either, but I think that's uninteresting and not what any of this is about.)
Nina Balcan Wins
I'm not aware of any examples where "Make X Y Again" was a positive thing.
> and second infections being more serious than the first. I vaguely think that there are some diseases like this (or perhaps I am just thinking of allergen sensitization.)

You might be thinking of dengue (which is endemic in my home region). There are four strains of the dengue virus; if you are infected by one strain, and had in the past been infected by a different strain, it increases the risk of the more serious hemorrhagic dengue.
It's ironic that Trump was elected, among other reasons, because people believed he was honest due to not being or acting like a professional politician, and incorruptible due to being wealthy enough to be self-funded.

And yet he's turned out to be the least honest, most corruptible president since maybe Nixon.

If only there was a decades-long trail of publicly available sources that could have shed some light on his personality and dishonest character... ah well.

At least his administration didn't use a private email server with flagrant disregard for security procedures, or get mixed up in a botched military raid that led to multiple civilian deaths.

Oh wait...

At least he's not a New York elite.

Wait, no...

At least he isn't a baby-eating pedophile cult leader and mass murderer. Or a Clinton.

That's better.
There are a few reports of people returning a positive test a second time. That is not the same thing as getting infected a second time.
Check this out, a 32 inch reflective LCD:

https://www.j-display.com/english/news/2016/20160520.html
Yes, "not a large group that had a positive blood test" would be better.
There's a logical inconsistency here. If we assume that the total number of cases is much higher than reported, then the hospitalization rate per infection is driven down by the larger denominator. There's a point at which there are so many total cases that the number of hospitalizations is problematic and noticeable. If we continue to assume that the total number of cases is much higher than reported, the death rate per infection (IFR) is also driven down by the larger denominator.
Did you noticed a performance difference between when encoding 30 frame chunks vs whole file (barring zero completion equals divid-by zero)?

This is wonderfully executed hack, for any feedback all I would have are nits. Well done, you have made my Friday.
Why is there being asymptomatic patients unbelievable? You believe some people can die from this virus, and some people can just have headache; but you don't believe some people may have no symptoms. I'm following your reasoning.
It's not completely without precedent, in that the 1918 flu pandemic was only a century ago. We don't have a ton of good data, but some researchers are looking at its effects in the US:

https://www.bloomberg.com/news/articles/2020-03-27/pandemic-...

But I do agree 100% with taken current economic estimates with a huge brain of salt, as our economic machine is far different from the past.
The scary part is already happening to drug users. The police in China are analyzing sewage to pinpoint who uses illegal drugs.
A Global Pandemic is NOT A BLACK SWAN. As matter of FACT, it was predicted by Taleb and according to him it is a WHITE SWAN.

The true problem here is the so called Risk "experts" do not understand Risk, and that is the core problem.
We could be about to see a massive re-pricing in goods & services, salaries, rent, commodities with disrupted supply chains, food, wipe out of businesses no longer viable, new business models suddenly viable

Or not, but if not, why not?
Checks back of napkin math;

Reported scandal is similar "confirmed" case testing as Italy and US. (only those showing severe symptoms).

20x population of Italy with ~1/2 the cases (so far)

4x population of US with ~1/5 the cases (so far)

Much more impoverished.

Virus originated there, so 2-3 months less warning.
My family lives in MD, and same thing happened to us in Feb. A child in our daughter's daycare came down with severe pneumonia and ended up in the hospital, our daughter was sick with diarrhea and fever for a week, and my wife caught a bad cough that lasted for weeks and had trouble breathing.

Thing is, we cannot know at this point whether everyone already has covid-19, since there are no anti-body tests. It is a live possibility, but meanwhile we are shutting down the world's economy.
Not enough to buy a car though, especially if you've also lost your job.
Any claim without sufficient data and reproducible results that the virus is unable to transfer via a surface, to me, borders on criminal negligence, given real research shows this is inaccurate.

As a counter to claim virus is “unable to live on surfaces”:

Virus was found 17-days after cabins on a cruise ship were vacated:
https://www.cdc.gov/mmwr/volumes/69/wr/mm6912e3.htm

Coronaviruses: How long can they survive on surfaces?
https://www.medicalnewstoday.com/articles/coronaviruses-how-...

First link is ambiguous as to if the samples taken were “toxic” enough to result in infection, but the second link makes it clear that virus survives on surfaces for days in quantities large enough to infect someone.
It has only been proven lethal for very old and people with chronic illnesses.

Those people should stay at home and practice distancing.
How do we know when we have arrived at something that is irreducible?
Show HN: The Controllable GAN Face Generator
The bulk of people who got sick enough to get tested and/or go to the doctor are still sick. Remember, the hypothesis is that there are a large number of infections mild enough to not be reported, tested, or hospitalized.
I wouldn't expect your local mexican restaurant to have an emergency stockpile of ventilators (as handy as that may be right now..) but I would expect most clever small businesses to have resiliency by keeping cash on hand, operational flexibility (can they switch to a to-go model?) and not over-expanding.

You can't prepare for specific black swans, but you can generally structure things to be more or less resilient. It's not even impossible for small businesses to gain during this time - my local wing spot is doing crazy good business because they've converted to to-go orders amazingly intelligently (curbside delivery, easy to get orders, high order accuracy, and delivery area is well managed by multiple employees).
Random samples in Stockholm measured 2.5% infected.
It’s really not. Even in a low cost of living area, $1.2K is about one month of basic living expenses.
On first install Firefox installs maintenance service that runs with admin rights and does that for you.
You can easily get ARM MCUs with parallel bus interfaces, stick a CPLD on and you can make ISA out of that. The trickiest part is likely ISA DMA emulation.

e.g. STM32H750 (< $10, Cortex-M7, 480 MHz, 1MB RAM) should easily give you room for emulating a 486.
Hardcore Firefox fanboy since its humble beginnings.

Since 60/Quantum, I can't think of a single UX change which hasn't been detrimental. Someone up top is souring the entire product in a misguided attempt to recapture market share. But all they're doing is continuing to bleed out remaining users, the majority of whom are likely somewhere between the casual and power user.
Wasn't there a POC of spectre that used a counter in a webworker as a timer?
Sorry if it's a stupid question, but hypothetically, would we be able to engineer rather than find a harmless strain of coronavirus with the spike protein of SARS-CoV-2?

If I understand correctly, antigens identify the virus by its S proteins. Would we be able to use the same methods <a href='https://www.nature.com/articles/nm.3985'>as in this paper</a> to replace the S protein in a harmless cold-like coronavirus with the S protein of SARS-CoV-2, and would then the resulting immunity defend against SARS-CoV-2?
I'm a power user and have like zero issues with the re-design. I noticed it the first time, said "meh" and continued like usual ...

Also FF/Mozilla cannot survive on power users & developers alone.
They are not talking about electronics or haircuts.

For example, many people have vowed never to step on a cruise ship after this and attending large scale events in person will probably give a lot of people anxiety for some time.
Huh? The key premise of the article is that the SARS-CoV-2 virus is mutating.
Excellent candidates can and do find ways to deliver value in their first week and more in their second. Even if it’s demonstrating the ability to learn how the product it deployed and how the team work, that ability to learn quickly and communicate with the team is valuable.
I assume you're not one of the 17+ million Americans who became unemployed in March?

In addition, there will be structural changes to consumption habits. Many meetings will persist online when this is over, creating a drag on demand for airline services. Cruise ships, large sporting events, and concerts will take years to bounce back.
Well, that would be evidence that it is quite extricably linked to the Trump campaign.

There is prior art for campaign slogans escaping the political world and transcending their original partisan meanings. "A chicken in every pot", "Don't Mess with Texas" ("slogan that began as anti-littering campaign; later adopted for political and other purposes" - Wikipedia), etc. Wikipedia also suggests it has been used prior to Trump, including by both Bill and Hillary Clinton (https://en.wikipedia.org/wiki/Make_America_Great_Again ).
The blood test looks for antibodies, so it detects whether the person has had an immune response to the virus.

The GP is pointing out that having an immune response to a first infection has not been riguorsly demonstrated to prevent future infection. If we are unlucky, immunity may only persist for a short period of time.
Given how difficult it is to get a test in many US states, the high number of reported negative test results should be surprising.
Just wait til you're hungry for a few weeks. I guarantee you're going to be more interested in buying canned beans than in a new iPad.
You are likely not the average American consumer.
It's been 15 days since March 25. Most of these people are likely already sick, and if their disease will progress to severe, they're already in hospitals. Massive death wave might be coming, but it'll hardly be unexpected, they're all factored in the models.
The machinery for making cardboard boxes is quite different than for n95 respirators. The cost of maintaining this dual capability at one factory would make the company uncompetitive. So eventually some legislator will cut the funding that allows the company to have this unused capacity.

It's like my company. We used to have a robust DR capability. We replicated our data to another site, and could have that site up (with all the servers/services running) within a 24 hour period. We had plans and equipment for running our call centers, for staffing at the secondary site, everything all bolted together in an annual exercise that helped us catch changes.

Then new IT management comes in and sees what they think is wasteful spending and view the annual exercise as disruptive. So they start to gut the entire process, instead relying on sandbox exercises for specific applications. Not taking a holistic view of our computing environment.

So now this manager gets promoted 2x for reducing "unnecessary costs", as well as improving productivity because IT no longer has to focus on that wasteful DR stuff...
WhatsApp uses Signal's encryption but it's hard to verify how much they changed. While signal provides a way to check that using cross-compiling reproducible build even for server code you can verify.
Yes, the original Javascript exploit from the paper still works, because the browser cannot mitigate this attack without just disabling parts of Javascript entirely which breaks Javascript.

With all current kernels built to mitigate these exploits, and all sane people running those kernels, there's no benefit in patching the browsers too, even if it were somehow possible, which for all intents and purposes it is not.

https://react-etc.net/page/meltdown-spectre-javascript-explo...
Here's an interesting one: https://www.j-display.com/english/news/2016/20160520.html
The United States is already in a recession, 45 economists say
Which blood test currently in use looks for antibodies?