skysight-inc/HackerNews huggingface dataset:
Our remote team (in SEA) adds a tonne of value to our local Australian based team; but they mostly do maintenance work and are heavily integrated into our local team (they’re quite literally just treated as remote devs, rather than their own company). It’s worked really well for about 6-7 years now
Hey, lowly Bio undergrad here, but how are you able to skip the RNA extraction step? I read the paper and you use the viral transport medium, but wouldn't you have to also purify RNA from that (or is it just much easier to extract RNA from that medium)? I also dived into the paper behind the "skip the RNA extraction step" methodology and it basically seems to swap out one RNA extraction kit for another (Qiagen RNeasy Mini kit and the Qiagen RNeasy Micro kit). Couldn't shifting kits from one provider to another introduce supply chain strain? (or am I just oversimplifying it?)
I do that occasionally when coaching YC startups with their HN launches (https://news.ycombinator.com/launches), which this is a variant of.
Isn't the recommendations by many countries to wear even cloth masks (e.g. the recent reversal by the CDC) _because_ there's a good chance COVID-19 can spread via large (i.e. non-aerosolized) respiratory droplets?
(Not that it doesn't also spread in other ways, but removing even one vector would be better in this case than not doing so.)
This too

https://www.vox.com/recode/2019/7/2/18691693/silicon-valley-...
Many people I know like this found a stable job in government or a large corporation and for the most part states put there. The may have had a few other jobs, but like you mention it's all enterprise stuff which moves slow enough.

They also have tend to have different motivations, whether that be a family or unrelated hobbies.

Tbh sometimes I envy people like this and sometimes I dont.
Ahh europe - where, anecdotally, all startup and eng is done backwards.
The Therac-25 paper.

http://web.mit.edu/6.033/2017/wwwdocs/assignments/rec-therac...

It presents a case study of the impact of a poorly build interface and the impact it can have on peoples' lives. If you do the work of a software engineer, you bear a responsibility for the systems and interfaces you build and the impact of how humans use them. The paper also introduces you to the important questions to ask about systems and teams in order to bear that responsibility.

It was the first paper in my university's Systems Engineering class for good reason.
This is a non-problem. There is no real threat model. It's like how you can cast to my TV if you're in my house. Sure, anyone could attack the party by posting porn on the TV but that's really not going to happen because I'm not going to invite you and put you in the wifi if you're the kind of person who does that.
> Rather than requesting bailouts and rule changes, imo they should be selling that stock to raise capital.

Sell stock to raise capital after airline stocks have dropped 70%? Usually you want to raise capital when stocks rise ( like tesla did ).

Also, if airlines start increasing float during a market selloff, it would put even greater downward pressure on their stock price and it would make their financial data ( EPS, etc ) look that much worse.

Your idea is one of the worse things airlines could do, but given their awful track record, they might do it.
Both the methods and David's twitter clearly describe the linear regression as the method and how it works with spike-in. In practice, it is a lot more complicated, as the signal-to-noise ratio can interfere with the regression and primer N-1 synthesis errors need to be accounted for. That is why we are willing to help other laboratories with our bioinformatics pipeline.
Lots of Russian ones - nomenklatura, maskirovka, arguably 'disinformation' itself, etc.
I'm glad this microservices hype is coming to an end. So many people have jumped on the hype train, introducing so much unnecessary complexity into their environments.
BlackRock and Microsoft Form Strategic Partnership to Host Aladdin on Azure
I've rarely not had an issue with shipping from Amazon. Turns out when you randomly gig-hire a different person every day for delivery, they never learn how to get into an office/apartment building.

USPS/UPS/FedEx have been sending the same person for years. They know where the mail room is, what the building hours are, who to call for building access when codes rotate, where the elevators are, where the emergency stairs are when the elevators are down, and where the units are.

Half the time Amazon delivery just leaves the package somewhere in the lobby or not even in the building.
I don't know, I think it's kind of messy to rely on overflow behavior to ensure that your element is in bounds. What if the size of the array changes later? There's no clear linkage between the two in my mind.
It's different for all kinds of of markets, in the markets we deal with (primary industries), our experience is, a lot of IE11 users are users with a lot of $ who have a lot of infrastructure built around older tech. The old tech keeps working fine, which is great in many ways. So, I think unless Microsoft kills it, IE11 is still the minimum for widest adoption. However, for my side projects, I just care about the evergreens.
I commented this earlier, here's an iOS/macOS client guide:

https://www.naut.ca/blog/2020/02/17/setting-up-a-wireguard-v...
Former TA here. I saw this happen several times with foreign students and domestic students. Maybe I could shed a little light on why this is this the case in most universities (mine was a public one in a large state for what it's worth).

Failing someone on the grounds of cheating at the university where I attended was a huge time investment. If the student contested their failing grade, the professor/lecturer who was the accuser had to go with evidence and present it before an internal panel. The student would obviously be allowed to defend themselves.

The outcome of the panel would rarely be in the favor of the accuser and against the student. The student would have to have been accused multiple times before the panel would take the complaint seriously. The punishment would end up being something like turning the failing grade into just one grade above failing.

When you consider how much a lecture gets paid, and how little importance teaching is given for researchers, you begin to understand why lecturers/professors just hand out Ds and move on with their lives.

The amount of times I caught people with MOSS[1] was too damn high. Never had anything come out of it so I stopped going the extra mile past sending the results to the person teaching the course.

[1] https://theory.stanford.edu/~aiken/moss/
After submitting this, I discovered:

If you click the coronavirus icon in the top left a few times, the data doesn't seem quite that bad...
> You’re likely the only “data person... Because people don’t know what data science does, you may have to support yourself with work in devops, software engineering, data engineering, etc.

Nothing has summed up my entire working experience more than this, it’s almost painfully accurate.

On one hand it’s an exciting challenge, you learn a lot and you get good at adapting to these situations.

On the downside I have practically no senior data science people to turn to for help when I do need it, which is frustrating.
People can donate to whatever causes they want. There's no regulation about "fairness" for voluntary aid.

Also, the tweet specifically said girls education after the Covid pandemic.
The free market is what works, privatization doesn't necessarily mean a free market was allowed.
A self-swab surveillance program has been launched in Seattle: https://publichealthinsider.com/2020/03/23/introducing-scan-... .

Is self-swabbing allowed there because it's for research purpose, not clinical purpose? The program does tell users whether they test positive though.
Looks like he edited it to remove now but parent comment was basically saying he's been telling customers to avoid shared hosting by using shared hosting in the form of Heroku, etc instead.
I don't think anyone cares but this story bubbled up to the surface. well done!
Seems reasonable, as dang explained the impact and the rationale.

Thanks Dang!
Well nothing at this point so the market illiquid for them. But if you can somehow sell the shares they’re probably worth a lot less than they were a month ago.
Honestly I think this just shows how disgustingly ridiculous Airbnbs spend rate is. In theory they should be able to shut down a ton of operational expenses like advertising, customer support, etc and weather a storm like this with a combination of cash on hand and limited loans but their determination to light ever dollar they get on fire means they might go under.
What dialect of SQL are you using?
Being partly responsible for increasing rent in the city, blatantly ignoring city's bylaws and zoning laws, having to deal with some Airbnb neighbors from hell while Airbnb preached the Silicon valley cool aid of we are changing the world and actually helping people, I would be lying if I said that I'm not a tiny bit happy to see this.

Already ton's of apartment have started popping for long term lease here in TO.
If he kept the shares until he died, his heirs would have gotten stepped-up basis so there would have been no capital gains anyway.
I thought AirBNB was recently claiming to have more than $1Bn in Cash on Hand. This seems like an extreme measure that wouldn't make sense if they actually did have that much cash -- right??
$ dig dns.wpodns.adtac.in txt

dns.wpodns.adtac.in. 3600 IN TXT "The Domain Name System (DNS) is a hierarchical and decentralized naming system for computers, services, or other resources..."
Stanford makes introductory coding course available for free during Covid-19
The standard whatever.fit(X, y) isn't very appealing but there are much more bespoke models that require creative engagement with stats/CS knowledge, e.g. Bayesian hierarchical models or deep learning models that are more complicated than what can be copy/pasted from Medium.
The concept of charity is arguably unethical, let alone noble.
There are already RCT studies that show it doesn’t really work.
> If you can't be bothered to take some basic steps for web site scaling (google page speed + a CDN) then the idea that you will carefully and successfully navigate to a 1 million tests per day moderate to high complexity medical test seems like it will be a stretch no?

No. :)

Seriously, these are orthogonal skills. I briefly worked for a communications satellite company that had a pretty godawful web site, but I doubt any of their prospective customers visited it and said, "Wow, if these people can't design a good looking web page, how can we trust them to put a satellite in orbit?"
Why is the WHO ignoring the asymptomatic angel of COVID-19? Wearing a mask will reduce contagion by those that don't know they are sick. Why is that not acknowledged?
I think if he doesn't donate it can get taxed as capital gains.
The days when IS&T developed custom software to run Apple are long past. The one exception may be Radar, which was developed in-house around 1990 and is a core system used widely in R&D.

Tim Cook probably couldn't care less about the internal affairs of IS&T. As long as they do their job and don't impose too much overhead on the company, it's all good.
This is much worse an issue if you live in a super new apartment in the suburbs. UPS/FedEx drivers know location very well. Amazon delivery ends up in a totally different location, marking it as delivered. I dont know how Amazon makes money when 2 out of 5 deliveries to my address were being lost or mis-delivered ️
Whatever engagement boosting algorithms are, they're not freedom of speech. I don't give two figs about whackadoodles and their conspiracy theories.

"outsource our critical thinking to private companies"

But by profiting off ignorance, that's exactly what media companies are doing.
It's App Store Connect now!
You'd think this was just an archaic relic but Bambora payment processing (which hasn't updated their site since uppercase HTML tags and framesets were a thing) has a userdir feature that lets their customers upload static file to their "secure webspace" which is hosted on the same domain for all customers.
Japanese is traditionally written top to bottom, right to left. Vertical typesetting (mainstream in print media but rarely seen on the Web, even though CSS has decent support of TB-RL CJK typesetting now) follows this rule, rotating any words from LR-TB writing systems 90 degrees clockwise.

The idea may seem unconventional at first approach, but this page’s layout—impractical as it is—is like a breath of fresh air to my eyes.
That's not the right question. The right question is, do we want to have airline companies running planes or not? And if "yes", is it an actual long-term profitable business, or is it "years of tiny profits followed by bankruptcy" a.k.a. something no sensible investor would invest in.
Making Aerogel
Job Security by Levels of Abstractions or Indirections (2012)
Buying treasury stock is what happens when you're undervalued in the market, but don't have many expansion opportunities. They don't want to raise capital because they don't think the demand exists for more airports, more supply: right now they're trying to compete on price, driving costs down. The airlines are not in a growth phase, raising capital seems incredibly silly.

They're also making the calculation that the people are leaving the market and selling under value. This makes sense. The market is low right now because of COVID-19, people need liquidity to handle underemployment and low-spending.

Profits are down and money isn't coming in, and treasury stock is an important counter-balancing force on a receding market. Airlines don't see any major opportunity to make money off of new infrastructure, so they're injecting that money back into the economy.

A pet peeve of mine, but you lump together investors and executives together as if having money in the financial markets is something reserved for the elites, and not inherent in every pension and 401(k) plan.
What you're describing is exactly how tarp bailouts of 2008 worked - government bought preferred stock. It was then promptly bought back over the next couple of years.

Truly getting rid of the mutualizing of risks would be letting the companies just collapse. But for various reasons (wanting banks, plane flights), we've decided to not do that.
I just feel like speaking my mind. It's a WIP.

The idea of the patriarchy really took hold. It's convenient to believe that everything is the fault of monstrous men. Meanwhile many men never really wanted to be an oppressive alpha anyways, many just want to love and be loved; perhaps focus on their projects. It seemed like a win-win, softer men can just be themselves, no more oppression, who needs the dumb alphas anyways?

But there's one big issue here: neither male nor female libido has changed. Women still get off harder when they feel it's their idea, that the man was the trophy. But to be honest with a woman is to be honest about the male libido, that it's not particularly difficult to hack into.

So in order to really get a girls rocks off, you have to be able to hack her libido. Whatever her game is, you've got to know how to play it. Which means you'll have power over her, she's thinking about you, the more she think about you the more power you have, obsession, etc. And if you hurt her, it's oppression. She never wanted this! Pay no mind to the men she's hurt herself, for they set themselves up for it. But you worked to do this to her.

I honestly think there's only one way to create equality and that's drugs that change our libidos to be more similar:
A. For women: perhaps a drug that makes them simultaneously aroused and hyper-critical?
B. For men: I don't know what it's like to be a woman. Women should design this drug.

Feel free to replace the words "men" and "women" with top/bottom, dom/sub, masculine/feminine, or whatever non gender biased terms suit you, if that's what you like.
Regarding UPS/FedEx I've found it varies based on where you live. I've had the same experience you describe before with long-time drivers. At my current residence it's the opposite, the drivers seem to switch out all the time. My door is hard to find so I notice when the driver changes.

Surprisingly Amazon has done the best in this situation because they incorporate a distinct step in their delivery protocol: the driver calls me if they can't find my door. I don't understand why FedEx and UPS can't do this.
Instead of buybacks being a "forced reinvestment", it would be more accurate to say dividends are a forced divestment. If the company spends $1/share on buybacks and you hold 100 shares, you can either keep the shares or sell $100 worth and get cash instead. If the company gave you a $1/share dividend, you couldn't use that to buy $100 worth of stock, because taxes.
MixRank (YC S11) Is Hiring Full Stack Engineers and Data Engineers
MixRank processes petabytes of data every month from web crawls, Google Play Store, Apple AppStore, and dozens of other sources.

DATA ENGINEER

We're looking for remote engineers to help with data mining, machine learning/data science, data transformation/ETL, data modeling, database scaling, and more.

PostgreSQL experience is highly desired (administration, optimization, DDL, etc). Also looking for experience with Python, Linux, Nix, and data mining.

FULL-STACK / PRODUCT ENGINEER

We're looking for remote engineers to build web applications and APIs. The ideal candidate is looking to grow into position of technical leadership in product development.

Experience with full-stack web development, Python, PostgreSQL, and Linux is required. Competency or interest in data visualization, UI, UX, and design are desired.

Email available in profile.
The author of the article, NADIA SCHADLOW, was a menmber of Trump's administration.
My blog is at jdrch.wordpress.com/, but most my activities are currently at https://github.com/jdrch/Hardware, a repo of all the hardware I run.

The aims of my setup are:

The aims of this project are to:

1. Run all major OS kernel families (BSD, Linux, Unix, Windows)
2. Backup all my machines
3. Provide secure, up-to-date, performant, reasonably private networking and computing functionality in my house

If you're interested in how a truly, hyperdiverse mixed environment can be scalably be managed, check it out :)
The cool part is all of these units that were AirBNB units owners are struggling with might get locked into year long leases to stem the bleeding, keeping them out of short term rental inventory for a year. This might cause a material decline in YoY revenue for AirBNB over the next year, depending on how long lockdown lasts, which is unfortunate timing considering their new financing arrangement.
> But for an equal amount of effort, raws and manpower you could get much more out of traditional manufacturing, much quicker.

The set of people who have 3D Printers at home, and the set of people with access to large-scale injection-moulding facilities (along with tool production) likely have a very small overlap.

I imagine those that do have access to those facilities were already trying to make those tools (assuming they wern't already occupied with other more urgent tasks). It just takes longer for them to scale up, and there's fewer of them in a smaller number of locations.
> I certainly hope so - Swarm is a wonderful orchestration system for small deployments (at least, I haven't tried to use it for large ones), and is really easy to use.

I would argue that Docker Swarm is a wonderful orchestration system for all practical real-world applications, with the notable exception of really global and gigantic multi-region deployments.

Docker Swarm works superbly out of the box and it's trivial to setup a multi-node heterogeneous cluster of COTS hardware and/or VM instances.
If I had to guess, it's by having typically 6-figure salary delivery drivers replaced with near minimum wage gig workers.

But yes, I've also noticed when my package ends up in a completely different building on the other side of town because of missed cardinal direction on the address. Our office manager has working relationship with the office manager on the other side of town with an address similar to ours because of how often they have to trade wrongly delivered/addressed packages/mail.
We have the data both with extraction and without and show that it does not make a difference with qSanger. In Figure 4, we add VTM directly to PCR reactions. Seracare VTM samples has SARS-CoV-2 viral RNA in a different capsid to prevent infections in a research setting, but otherwise it reflects real-world VTM samples (and much more realistic than even what EUA requires).

By the way, this robustness is completely expected, as any impurities in VTM would impact spike-in and endogenous viral amplification equally for end-point PCR (so their ratio stays the. same). This is not necessarily true for qPCR where an impurity (caused by lack of RNA extraction) can potentially cause a positive sample look like a negative when the viral RNA does not RT-PCR.
Web MiniDisc has added new life to the format. It lets you manage the contents of a MiniDisc ..from a web browser, thanks to WASM. Add MP3s, FLACs etc.

https://stefano.brilli.me/webminidisc/
If I remember landlords tried this in California 30 years ago and the state just up and made it illegal.
We try to stick to ANSI SQL as best as we can, but we have own own dialect. This should be a good entry point: https://www.questdb.io/docs/select
I agree most of American history is charged and comparing civil wars makes sense, but I would add that much of the US government interaction with the first nations seems generally comparable as well. The history of Oklahoma, boarding schools, allotment, and the recent pipeline protests are four particular areas (there are many others) that are very charged today.

Looking at it a bit differently, Texas history, where a bunch of ranchers decided on their own to expand the US, could be comparable as well and is still charged today.
Well, I certainly expect their CFO did the arithmetic and found that their best path forward is to do this deal. It could be they can survive here for quite awhile and just burn cash. But if this pandemic goes on and on for 18 months they’d be in serious trouble.

So maybe this is asking for cash before it’s too late? Maybe this is the insurance they’re now buying.
Why does AirBnb need a billion dollars?

I can't find anything suggesting they're spending more than $100mm on their ongoing litigation, the technology isn't particularly novel or complex, is the rest just going to compliance or to pay for previous commitments?

Just seems like an absurd amount of money. That's like one year of revenue for them.
I think this is great. As you wrote, you have the luxury of comfort in the midst of all this and are offering what skills you have to those who might need them. My tiny non-profit is applying! Thanks for doing this, it's lovely.
Are you there protesting the NAACP because, gosh darn it, white is a color, too?
Part of the issue here is that we're running into a topic I am extremely, unreasonably nerdy about, since the first post-RTM working overflows are the K-T boundary of computer security. Having a working stack overflow on SGI MIPS, a delay-slot architecture with a split I&D cache, would have been a very big deal, and would force me to revise a mental history I've been grooming for a very long time. I believe Aleph One. :)

(We go back too, him and I; I met my wife at a party at his apartment).