skysight-inc/HackerNews huggingface dataset:
Do PTLDS patients actually show active antibodies against lyme? That would be a good indication what’s going on.
It's one of the most reliable metrics we have, and a lot better than just tests or just confirmed cases.

After you have this info, you can compare the rates to what kind of testing policies the areas have, and make some initial conclusions.
Maybe you can help me understand a simple example - if there is a gene that controls the eye color, how does it express itself as eye color (vs something completely different)
It's hard not to draw analogies though.

For example, the covid-19 virus's RNA ends with AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA (33 As) which, as someone pointed out, looks suspicially like a "NOP sled"[1] (i.e. so that a protein coming in hot can hit anywhere on the sled and then slide down to the actual information)

[1] https://en.wikipedia.org/wiki/NOP_slide
Venezuelan ship sinks itself after ramming cruise liner with a reinforced hull
Oita Partners with Virgin Orbit to Establish First Horizontal Spaceport in Asia
In the end, yes deaths are most important, but in order to make temporal decisions that affect that number, we need infection-related data first.
Sorry, I don't understand. How would the framework know what the dependencies are if you don't declare them, even indirectly in some fashion? In what sense are they dependent?
To clarify, a good burr grinder is also good for fines. You can set the Encore somewhere between 2-6 and make your own Turkish coffee grind using whatever beans you've got lying around, rather than paying for a can of pre-ground Turkish coffee that's probably been on the shelf for months already.
Tesla soars on delivery numbers – company delivered 88,400 vehicles in Q1
>> A recent study in humans demonstrated that B. burgdorferi DNA was identified in PTDLS patient by xenodiagnosis but unable to culture viable spirochete17. In about 85% of Lyme arthritis patients, B. burgdorferi DNA was detected in synovial fluid by polymerase chain reaction (PCR) testing

The previous sentence is also important:

>Many research studies has [sic] shown that B. burgdorferi establishes persistent infections after antibiotic treatment in various animal models.
Yes, this is very important. But one should not forget also the avg. hospitalization time (which will go down once we have clear procedures for treating COVID in different stage)
Why do you think differences in men and women would be limited solely to communication? You don't think millions of years of sexually dimorphic specialization might have lead to different behavioral tendencies? What about different hormone serum levels and metabolism?

This utopian Western notion of the mind being a perfect clean slate from birth has no basis. Do you really think that the mountains of evidence, in the form of gender discrepancies which have been almost universal across time and culture, can be so trivially handwaved away as "social constructs"?

What about different behaviors in other sexually dimorphic mammals? You know, like, literally all of them?
There's a difference between the US President and a single warehouse worker, no?
former expat in China, youtuber serpentza, finally unleashed the hounds with his experiences about animal eating over there:

https://youtu.be/rbHxeOQA1Mc?t=505

Hard to argue with. Totally gross, too. But I love eating cows, chickens and fish and see dogs as companions so whatever.
I've just reproduced the described behavior via a test message from Gmail.

On the other hand, I've also just reproduced it via test messages from every other one of my email accounts, across multiple providers as well as the various instances I run for my own use. The only one that didn't repro was Office 365.
> sprint velocity goes down by 80% and bug counts go up by 90% as stuff randomly breaks in the refactor

Do you mean during the refactor, or after they claim it's finished?
> Probably a side-effect of what I usually choose to comment on, which are things that are objectively wrong or seriously misleading :) I think the HN voting system is poor, so I don’t use it, myself.

Do you have any evidence that you do not use it?

> Remember, an arrow function shares the same scope with [its] parent function
>> Exactly like a non-arrow function, then?

No, not exactly. It looks like I need to be more explicit, here goes: Remember, an arrow function's BODY shares the same scope with its parent function

> Do you have any evidence to the contrary? I have experienced it when processing heaps of textual data in nodejs (the same engine that runs chrome). My script was crashing for no apparent reason, and just changing the arrow functions solved it.
>> Not only is that not evidence, it doesn’t support what you originally said.

It is called ANECDOTAL evidence, and yes, it is a thing. If you want SCIENTIFIC evidence, sorry I just do not have the time and energy. If you want to believe that arrow functions are a drop-in replacement for normal functions and that they are always better and faster in all situations, go ahead and believe that. And you'll do just fine, as long as all you are doing with JS is React and basic UI wrangling stuff.

> Slower ≠ crashing for no apparent reason.

My friend, this is a discussion, not a scientific thesis or a legal document. I do not have to explicitly explain every little detail and cover every little phrase so that someone does not misqoute me. Be generous enough to try and understand something someone is saying. So, to rephrase that too, when I say "crashing for no apparent reason" I mean "crashing for no apparent reason that I could find by looking at the code over and over again searching for bugs or typos". And yes, it was crashing due to timeout and memory issues. Please dont start arguing about how crashing and timing out are not technically the same thing.
Wow. This will be a good example in GPL versus MIT license debates...
Just paying for the bare essentials: rent, utilities, food and toiletries.
Everything else is going straight into the stock market.
I feel sorry for the author but it's somewhat ironic that Quillette published this article considering their strong Libertarian leanings. It's years of misguided economic policies built on baseless and fictional Randian ideology trumpeted by publications like Quillette that got us to the point where the largest economies in the world with the most resources are suddenly the most ill equipped and dangerously unprepared nations in a global crisis.
> Isn't this the actual, living, real motto of SV? Move fast and break things.

Not all of us are in SV. And some of us go to great lengths to not break things.
I'd be more interested in VOC sensors or PM2.5 sensors.

I feel like PM sensors are easy to understand. I wish i had a better grasp on VOC/TVOC though.

It's hard to interpret what an elevated VOC from my foobot actually means.
Yes, but if Google does it it's worse ¯\_(ツ)_/¯
Unsurprisingly, Protonmail strips the IP address.
Just like toilet paper, it seems.
I feel like security is a realm where that quote is demonstrably untrue. A "hole" in your system is exactly zero problem until the moment someone exploits it.
My initial thought on Ibuprofen is just correlation not causation. How many people who get a fever will try Ibuprofen to try to lower the fever? Probably quite a few. When these people die its easy to say "well they all had Ibuprofen". That doesn't mean it had any effect.

On the flip side, NSAIDs do reduce inflammation and inflammation is part of the body's response to various stressors; I could see that lowering our response leads to worse outcomes when sick. I have always thought that cold medication increases the duration of a cold just from my own observations, so I do find it at least plausible.

I agree on the high blood pressure, if you are on it that means you have hypertension and are likely in poorer shape than someone who does not take it. I can somewhat see diuretics having an impact though as those can flush needed minerals out of your body when your body is in need. They also dehydrate you, so if you are on one and don't get properly hydrated and have a proper mineral balance, I can see that being a big negative.
"Antibodies normally persist in the blood for months or even years after the infection is gone; therefore, the test cannot be used to determine cure."

https://www.cdc.gov/lyme/diagnosistesting/index.html
Grimes posted the music stems and video files for her single so anyone can remix
This is likely why they really push you to install the app, rather than use the browser version.

They have a lot more ability to ensure it works when it's their own binary. When you're relying on a bunch of browser functions, it's way harder.

The browser version is a last resort.
I go shopping more because the store won't let me buy enough food in one trip.
Is has been observed many times that there seems to be an inverse relationship between the qualifiers in the name of a country and the conditions in said country.

Example:
http://www.sandraandwoo.com/2019/08/22/1108-republics/
This is how SMTP is supposed to work. As a side note, messages sent with Outlook or webmail using O365 (or Exchange) don't go from your client to the O365 server over SMTP, but your IP address is still shown in the X-Originating-IP header.
Had to `apk add gawk` is all.
I'll review the citations in this study once again, but the evidence for lingering spirochetes in humans is always thin. Much of it relies on indirect testing that is difficult to replicate or prone to laboratory errors.

I'd love to be completely wrong and for this to be a game-changing solution, but after years of following this research I'm suspicious of the idea that persistent yet mysteriously undetectable (in humans) spirochetes are responsible for PTLSD symptoms.
This is "Working as Intended" (and Google told him exactly that).

Gmail and other providers have to split the balance between privacy and security. If you use the web interface and they authenticate your device directly, Google hides your IP and takes responsibility as the "source" of the email. If you're using SMTP it is possible you could be relaying mail for others (even possibly as an open relay) and they will disclose the IP of your client or mail server.
> but the moment you walk into a homeless shelter asking for a meal funded by the people in the rat race that you like to condemn and opt out of, I'm afraid my opinion starts to matter.

Well it's a fair trade off. Much of land has been commandeered by the state for the people in the rat race. So the homeless getting a meal from a homeless shelter doesn't seem so hypocritical.
mailbox.org appears to not include it
This is what is supposed to happen. I guess I agree though that we could get rid of it as normal users dont know this is how email normally works. It's useful though...
The Steve Jobs Nobody Knew – Rolling Stone
The cliff notes version of it is that DNA encodes the information on how to build proteins.

https://en.wikipedia.org/wiki/Central_dogma_of_molecular_bio...

Proteins are built out of a chain of aminoacids. There are 20 different kinds of aminoacid, and the particular sequence of aminoacids determines the shape of the protein, and therefore its biological function.

https://en.wikipedia.org/wiki/Amino_acid

To build a protein, the cell uses a strand of RNA as template. The RNA consists of a sequence of 4 kinds of bases (A=Adenine, C=Cytosine, G=Guanine, U=Uracyl) and there is a genetic code that maps each group of 3 RNA bases into one aminoacid. For example, "AGC" corresponds to serine, "AAG" means lysine, and "AGCAAG" means serine followed by lysine.

https://en.wikipedia.org/wiki/Genetic_code

DNA is built of similar pieces as RNA. The main difference is that RNA is single stranded, while DNA is double stranded with that famous double helix structure. Additionally, DNA uses T=Thymine in place of U=Uracyl.

DNA acts a store of information. Each gene contains the genetic sequence that describes how to build one protein. When a gene is active, the cell copies that part of the DNA into a messenger RNA, and then uses that RNA as a template to build the protein in question.

Every cell in the body has the exact same set of genes, but they differ in what genes are active at each time.

------------------------------------

Now on to viruses...

The Coronavidus is an RNA virus. Each individual virius is a little ball made of proteins and lipids, encasing a genome made of RNA.

By itself the virus is inert, but once that RNA finds its way to inside a human cell, it behaves like a fork bomb. The cell translates the viral RNA into proteins, just like it would with our own RNA. One of the proteins is a polimerase enzyme, which then makes even more copies of the viral genome. Soon, there are thousands of copies of the virus. Additionally, the viral genome also encodes the structural proteins for the capsule of the virus, including the "spike" protein that gives coronaviruses their signature look.
Hm... just the words loses so much -- the tone, the emphasis, the pauses. I think we'd have to do at least audio. Though of course expressions, hand movements and bearing count too, so I'm thinking we need a number for video as well.
With O365, your IP should generally be in the X-Originating-IP header.
Have you tried BigBlueButton?
How does graham reproduce? How does graham poop?
I've filed an issue for me to add a support email link. Will do another dashboard release in a couple days, thanks.

As for alternatives, we tried chat but no-one used it, and it added a ton of heavy awful javascript to our website. You can file issues on https://github.com/tailscale/tailscale, though for the dashboard I'll move them elsewhere. Also we have been looking at various pieces of "forum" software too but haven't settled on anything we really like.

Could you elaborate on the errors you saw? If you want to send support@ an email with your account email address and rough time, I can look in the server error logs and try to hunt it down. Thanks.

(I work on Tailscale.)
I think the pace is also somewhat fast and lot of umms or /and repetitions of certain world like "right".
They were giving out issues of Increment freely in their recruiting events IIRC.
You can also require users to be authenticated (through SSO or other mechanism) before they log in, which could defeat some impersonation attempts.
It's an FDA-approved drug. Doctors could potentially just prescribe it for off-label use.
Two of the most common types of plastic are low-density and high-density polyethylene (LDPE and HDPE).

LDPE is cheap and flexible so is really common, especially for things like packaging. It also deforms near the boiling point of water. If you've had a bad experience like a plastic container melting in the dishwasher, or a soda bottle shriveling when filled with hot water, it was probably LDPE.

But there are other plastics like HDPE and polypropylene which are perfectly fine at 100°C. If you're using a plastic product designed for use with hot liquids (like nalgene or aeropress) it will be made of these materials.

I still felt nervous the first few times putting boiling water into a nalgene bottle...
Amazon always brags that they have twice as many Windows VMs running as Azure.

I’m by no means a Windows hater. I’ve never developed on anything professionally besides a Windows computer - these days .Net Core, Python and Node. But once I started working with AWS, I avoided deploying to Windows servers like the plague. Anytime you add Windows to the mix you basically more than double your cost between Windows licenses and the increased hardware required over running Linux.

All that to say, no one chooses to use Windows on AWS. So if there are that many Windows instances on AWS, they are more than likely old enterprise workloads.
If the formula is (a & b) | c, then it is easier to be solved by a computer than by a human. With three variables, there are only 8 possibilities, so you can bruteforce it. (64 or 128 if you can use `not` too.)
Protonmail does not support SMTP at all, so I'm not sure what you think they would be stripping.

Both Protonmail and Gmail hide the IP if you're using the web interface.
To me, what blows most comparisons and analogies out of the water, is the insane complexity to it all. That genes can influence and interact with each other. So gene expression (= gene -> protein) can change gene expression, e.g. based on environmental factors or folding of DNA etc...

Gene A is responsible for property A is way way way too simplified.
They're working on the new one: https://www.newsweek.com/lyme-disease-vaccine-valneva-fda-ap...
Monitoring CO2 levels? Personally, I want a discrete meter for monitoring levels in meetings... especially large design/product discussions. I suspect some of our meeting rooms have poor ventilation and CO2 build up contributes to increasingly dumb discussions.
A poly A tail is at the end of the transcript, not the start. This is a perfect example of the dangers of analogies because this one is completely incorrect. Poly A tails protect RNA from degradation. A ribosome will not bind to that part, it will bind to something within the 5' untranslated region on the other end of the genome) ribosome binding site, kozak consensus sequence, etc). If you bound to the poly A tail and slide "down," you'd just slide right off the end of the gene.

Definitely nothing wrong with trying to find things that look similar across fields and try and gain differentiated insights, it's certainly an admirable thing and an important part of making many discoveries. But a first principles understanding of the structure of DNA, what a 5' end and a 3' end is, and how transcription/translation works (all bio 101 type stuff) would provide a much better foundation to do that with. You don't need a degree in biology to know the basics, just like you don't need a degree in CS to know the basics, but it's worth learning the basics if you want to get an understanding of the field or work with it.

https://en.wikipedia.org/wiki/Polyadenylation
DNA code (acgaa...) is not the only thing to be taken into account. Folding of DNA is just one more factor that influences outcome aside from raw code.
There's also annoying variations in GSI's - you need separate images not just for 32-bit vs. 64-bit but for A-only vs. A+B boot support, and sometimes for different "base AOSP" releases - GSI's for devices that shipped with Aosp versions 8.x, 9.x, 10.x are not always guaranteed to work consistently.
Even alone having to implement this (and perhaps become sued if there is a bug in the code) is a massive liability for the business.
even with das coolz english words sneaking in, and markers becoming markers, it's half-assed, in true slav style. the new russian cool-kids did ditch 'winchester.' and replaced it with 'stiff disk'

however anything that's a usb stick, be it a modem or wifi card, is still 'flashka.' sticking a cell modem in a usb port makes it flash memory. i hear with usb-c new lingo will take over. anything usb-c will be called djest' (stiffness)
ProtonMail does support SMTP via a bridge:

https://protonmail.com/bridge/

tho not clear if dannyw tested with ProtonMail IMAP/SMTP Bridge or with ProtonMail web.
It’s not an egregious flaw, any more than the telephone numbering system is. It’s a design decision to improve usability that is generating a lot of noise during an extraordinary period.

Usability is the zoom priority, and the reason why people who already own more secure, no cost, solutions like Teams, Skype or Google Meet buy Zoom.
A Redditor shares her story – “I was tested positive for Covid-19. AMA”
The US mil gets its ammo mostly from Lake City and Federal. The latter does make 22, but basically a separate company. It was election panic at first; the irrational buy-up. Everyone was out from European to Russian suppliers.
While there's lots of interesting points in the thread, I'll focus my response on this one.

1) I completely agree that the title 'Nonviolent' is awful. It doesn't even follow the NVC principle of 'say what you want, not what you don't want'. The original author conceded to this. However, you shouldn't judge NVC by its title.

2) NVC doesn't purport to resolve the issue of the bugs or velocity, it aims to help resolve the conflict between the sales manager. Gosh, if NVC actually changed reality that would be awesome. Instead, it helps you find solutions given reality, which is actually very helpful.

3) I sense a lot of irritation and frustration in your tone because you want to be spoken to like an adult. Fair enough—that is a universal need. If you'd like to get your boss to 'give it to you straight', you could NVC to get what you want, without sounding self-righteous :)

Hope this clarifies.
Podcast: Right Back at Ya – Stack Overflow Blog
Official author GitHub repository:
https://github.com/BernhardSeybold/Chesspresso

Has had some very minor fixes since the last source forge version.
I have a CS background and for me the best explanation of how life fundamentally works was the MIT 7.00x "Introduction to Biology - The Secret of Life" course. It is absolutely amazing, requires only high school level knowledge and covers so many incredible stuff that I cannot possibly list all of it here. And not only is this course teaching you how stuff works but also the history behind it, how we, humans, figured it out. And, it's free and available online!

If you ever wanted to get deeper into biology than reading news articles, I cannot recommend this course enough.
Wow. I was literally about to reply with the same exact thing (built my own as well)! No value in this comment other than to validate your comment.
Ways to help the fight against Covid-19 from home – Stack Overflow Blog
Round for round there is nothing more compact than 22lr. Maybe you are right; but having worked at a range, we used to buy pallets at a time of it. The demand was definitely more than production supply.
Your post reveals that you are viewing things through a political lens.

It's true the administration could have acted sooner. It's also true the opposite party was smearing 'racism' and 'xenophobia' even as shutting flights down was obviously the right move. This is not a scenario where any politician can claim to have done better.

In fact, world-wide we have seen a variety of responses, with no definitive answer on what has been good and what has been bad. It's a horrible situation for any national leader.

As to the number of dead.... it is what it is. Is it good? Certainly not. Could it be worse? Certainly. Does anyone have all the optimal answers. Certainly not.
Class vs. Struct in Memory – iOS and Swift
Every other industry.
Thanks for posting the bounty. Awesome! I wonder if it would make sense to add a virtual mic output as well so that the video and audio can be synced together, for ie when someone is using OBS to Zoom... I've gotten it to work via pulseaudio routing but the audio isn't automatically synced.
Let's hope the FDA does its job of ensuring it is safe and actually works as its proponents say. I'd rather they not give it 737 MAX style review.
JPMorgan says it's not ready for small business loan applications
https://virusoutbreak.wtf
There's over 30 million deer in North America. And moose, and antelope, and bear, beaver, elk, geese, ducks, quail, pheasant. I think there's plenty of wildlife to feed us.
I've found most right wing folks immune to updating their worldview in the face of contradictory evidence and have come to the conclusion they are to be beaten, not reasoned with.
Just meaning that if you didn't conform to the tribe's rules, you would be exiled... and exile meant death.

Being part of the community mattered way more in tribal society than modern society.

That also means the tribe was close knit, and would take care of sick and disabled members... as long as you followed the rules.
Bad

satirical

news

site.
https://slatestarcodex.com/2018/08/23/carbon-dioxide-an-open... gives a decent reason why you should care about controlling (and thus monitoring as a first step) internal CO2 levels.