skysight-inc/HackerNews huggingface dataset:
Lyme has three known forms of existence in mammals:

1) spirochete reproductive form and susceptible to a number of antibiotics (vitro/vivo)
2) round body "starvation forms" which are resistant to most antibiotics (vitro/vivo)
3) biofilm colonies which harbor many pathogens, metals and mycotoxins are resistant to antibiotics (think immunosuppression here)

I've gone through a shit ton of tests in the last few years going over much of this. I have relatives that experienced it as well. There is growing scientific evidence a ton of clinical improvement, yet "anecdotal" patient evidence that many of these pathogens can persist beyond initial treatment. Buhner does an excellent job of explaining some of this in "Healing Lyme" and backs it up with studies from around the world. His protocols certainly help people (myself included).

Immune expression and context is a tough nut to crack and we need billions of more data points capturing cytokine signaling in conjunction with T-cell, Nk cells, mast cells, antibodies, etc to get a better understanding of HOW UNIQUE EACH IMMUNE RESPONSE IS TO A PATHOGEN. Life on our planet is biological and tightly coupled with bacterial/parasitic/viral pathogens and would not exist without them. Things quickly change through reproduction or in the case of Borellia by shifting its outer protein to better evade compromised immune systems. Or has there just been one flu/corona/etc viral strain in the last hundred years? (<- No). These things have remained in existence for a long time, it is foolish to think they cannot adapt.

Mind the 'gap' with disulfiram. It seems side effects vary, but also the quick elimination of Lyme, Babesia (not sure about Bartonella, which is mainly endothelial), and the cytokines cascades they trigger, but removing them all it once vs reducing them from severe to immune manageable levels might cause its own set of issues.

I won't bring up the CDC as they've failed millions of Lymies at this point with poor test protocols and failure to push for more research data. Test skipping 31, 34 antibody proteins when they are primary Borellia proteins (if the body is able to produce them, immunocomprimised or the load from multiple infections). The single dose doxy is absolute bullshit (1 data point from me). The denial that ticks can transmit Borellia (Lyme) and Bartonella in the same bite (bullshit, many tick samples on both costs show something like 2.6 pathogen average). In my personal experience, Bartonella is an absolute bitch to get rid of.

We need to better educate ourselves by owning all of our data in a way that enables us to submit it to research projects that are publically funded and not driven by patent revenue which pushes economies of scale. (off soapbox now :-)
People like slack because using it feels like "working".

It's not. Everyone who has described to me how their "productivity" went up because of slack I am able to explain away. It's not work, it's keeping up with slow chats and a mess of interlaced conversations. That's not work.

Test: In a popular channel wait until someone asks a question. Immediately then post another question. This should be ok behavior (it is with email). See what happens. The previous one quickly goes away as other people type. What a mess.

Chat isn't how work gets done, it's how people trick themselves into thinking they are "working".
I'd have a lot more faith in this story if I could see the memo for myself. Vice is not above twisting people's words and taking them out of context.
Every second, we are constantly and automatically distilling insane quantities of internal and external stimuli into much simpler -- but still incredibly complex -- webs of categories, associations, and relationships. Each moment of awareness is composed entirely from these mental constructions.

We also analyze and modify our representations in various ways, both consciously and unconsciously. Science is one of the more explicit processes for doing so.

Of course, much of reality is lost and distorted in the process. But we do the best we can :) I like to think we make better maps of reality now and then.

I suppose, at the very least, some of the maps we currently possess can be used to enact more dramatic change in the world around us than ever before, which must say something about their truthiness.
You can't extrapolate trends ad infinitum, and I didn't.

I extrapolated them for four weeks.

All we need is four more weeks of what has happened for the last two (and most authorities are saying that the lockdowns will last at least this long), and we're at the peak of the Great Depression, unemployment-wise at least.

Moreover, by assuming constant linear growth, I was being optimistic about the slope of the curve. The second week of jobless claims was worse than the first.
This is very cool. I had to write something in the near realm a few year ago, and love your implementation.
Hello I'm a Software Developer looking for serious projects to work on

Location: Matanzas, Cuba

Remote: Yes

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<IMHO>

It's horses for courses, but for me, threaded IM is a _terrible_ UX.

Real time conversations gets hidden as so much is buried in the the real time thread.

But for regular forums threads are perfect and make total sense.

Similarly, it seems like a terrible UX to have IM style conversation on a blog or news site.

</IMHO>
My guess would be that they wear and wash reusable pads. There are modern versions of these, too! Thinx is the big name brand.

Either that or they don’t use anything. Not to get too personal, but it’s not always necessary to use something aside from regular undergarments.
Yeah... graft it on after you've lunged to make a sort of OK product and they're locked in but the vulnerabilities you're exposing them to aren't worth moving off the platform. The capitalist sweet spot
I don't think your cloudflare link supports your position. CF talks about "The TCP/IP relationship..." - in context they are clearly referring to tcp and ip as two separate nouns, not as a single noun to refer to the internet suite. Context can modify word meaning-using that as an example really doesn't say anything about the term "tcp/ip" in general.

Fwiw Wikipedia also thinks tcp/ip means the protocol suite https://en.wikipedia.org/wiki/Internet_protocol_suite (edit: i guess other person already said that, i didnt notice)

Edit2: otoh, i think this whole argument is pedantic and its clear what the original article meant.
Because in this case, the measure is 0 percent effective. People work together every day. This virus spreads super easily. Telling people to stay home once they show symptoms does absolutely nothing to stop communal spread. If it did we wouldn't have these social distancing rules, and the entire country wouldn't be shut down.
Ask HN: What is the best way to modify the metadata of audio files in Python
Very cool.

I have the Bash equivalent (sorta) on my bookshelf and has seen a lot of use. ('GNU Introduction to the Command-Line').

It introduces a command, describes the options in detail, and then the next few pages for each command are useful bash (mostly) one-liners.
https://imgs.xkcd.com/comics/placebo_blocker.png
Expectations are also much higher.
I wonder if people would chip in to pay someone to do it right.
Spoken like someone unfamiliar with how thoroughly constructed the most striking nature photography typically is. From shooting in wildlife refuges and representing the result as taken wild, to freezing insects so they can be posed and otherwise manipulated in macro work, to cutting and arranging foliage to compose "garden" shots, there's a vast range of what you would call "fakery" that goes into creating those images, even before they come out of the camera into Capture One or Lightroom.

For what it's worth, I'd call those techniques "fakery", too. I don't hold with them, and I don't buy the argument that they're what pros do and it's only from my privileged position as a dilettante hobbyist that I can afford to sneer. (1) But maybe it's worth saving your ire for that kind of nonsense, instead of aiming it at the manipulation of light that's absolutely central to every kind of photography.

And, in any case, I see nothing in the article that suggests the photographer has tried to claim these are sunrise or sunset shots, or indeed anything other than what they actually are, i.e., made with the use of off-camera flash. The interpretation based on which you're calling them fake and misleading isn't his; it is yours.

(1) Which is an argument I've actually heard before, and all I can say is, when I hear it from somebody who can outdo work of mine like https://aaron-m.com/wp-content/uploads/2019/07/DSC_9393.jpg - taken from a distance of six inches, and with that wasp's sisters buzzing around my head - maybe then I'll think about taking it seriously enough to explain why it's bullshit.
We Don't Know How to Compute
One thing I've always been curious about with JackBox is if it does anything when everyone's on the same LAN?
PittCoVacc: Covid-19 Vaccine Developed by UPMC and University of Pittsburg
It as almost if self-inflicted wounds are best wounds.
ACM Publications Freely Accessible during the pandemic
To help support our community working remotely during COVID-19, we are making all work published by ACM in our Digital Library freely accessible through June 30, 2020. www.acm.org
Interesting. Connected the the “Learn a Language” box, the only one the author personally recommends is Javascript. All others are labeled as alternate options and while I know this is a subjective resource, that still seems odd to me.
Show HN: Jeo.py, a CLI for keeping score to Jeopardy written in Python
This is a disaster and more likely to put a newbie off or confuse them than to help them.

Why is the largest callout dedicated to WebAssembly, noting it as not ready yet? Why is "Using DevTools" near the bottom, branched off PWAs instead of near the top? Why are server-side things like Apollo on there, above things like static site generators? Why are mobile and desktop applications on there? There's a stack of "Redux, MobX, RxJS, NgRx, VueX" boxes along one side with a tick next to each one. Who is that supposed to be helping?

How is a newbie trying to get into front-end development meant to make sense of this without being completely overwhelmed? I know developers with years of experience that would be scared by this; it's one gigantic imposter syndrome trigger.

In order for a resource like this to be effective, it needs to prioritise and contextualise. This reads more like a "look at all the things I know about" boast. Less is more. A resource that aims to actually help newbies should be at most a quarter of the size and actually provide context and priorities.
A lot of felonious toddlers out there are getting away with it, too.
>horrendous security flaws

You’re kidding... right?
Pentester here. Absolutely something I would look at and abuse. You're disclosing information, allowing the harvesting of valid email addresses, and allowing access to an account. even if only in a limited capacity for email management, based on only the email. There's no reason to do it this way.

See here: https://portswigger.net/web-security/access-control/idor
Check out Primitive Technology on YouTube for similar.
ACM has done more than make Leslie's book available. The Digital Library is an amazing resource. You now have no excuse for wasting time while waiting for the pandemic to resolve. Kudos to the ACM.

The notice published on the site:
To help support our community working remotely during COVID-19, we are making all work published by ACM in our Digital Library freely accessible through June 30, 2020.
Yes now Google meet uses random alphanumeric meeting ids this helps for sure you needed to find the.balance between security and accessibility.
Any cosmetic damage? You haven't played Forza Horizon recently then. While crashes aren't BeamNG.drive-level disassemblies, they do scratch up and can make cars undrivable (especially with full damage turned on).

Any they have a fairly comprehensive list of manufacturers and no cars are immune to damage in the game.

https://forza.fandom.com/wiki/Category:Manufacturers
So it works...? Placebo effect is real, measurable, and helpful.
> I took a two day workshop on communications at work (not NVC). They did a survey of the class: How many people think facts, and not feelings should be the focus of a discussion? And how many felt the opposite (focus should be on feelings, not facts)

That is endemic with society today is that people don't seem to think facts important.

Also a two day communication workshop on how to talk to people. You have bigger problems than how to communicate at work.

> You've already alienated half of the population. Good luck at resolving a conflict with them.

And that is their problem. Why is it mine? If you are an adult you should be able to talk about things as a matter of fact. If you cannot you are not an adult. Some people don't grow up past 16 years old. That is their failing and not mine.

> But I'm crazy to think that half the population will spend the effort to get there. A big chunk of them don't view it as a desirable goal. It's a laudable aspiration for me to try to make them think that way, but unless I want to make it my life's mission, I need to focus on getting results now, and that means discussing their emotions, and realizing that in doing so I'm not going for an inferior approach.

Sure. You have a choice as to whether you want to work with those people or not. I don't like working with those people so I minimise the amount of time I spend working with them if possible.

> Oh, and people who say feelings are irrelevant? Let me completely dismiss them in a meeting and suggest mildly that they're perspective likely is due to a lack of competence. Most of them will not perform well for the rest of the meeting. Quite a few of them will have issues with me in the long run.

There is a difference between openly hostile (which is what your example is) and talking about things as a matter of fact.
Chicago may have a "confidential" plan, but the State of Illinois has a public plan [1] which they finished updating March 2 after participating in the "Crimson Contagion" exercise last year. I personally think that the state and Chicago are handling things pretty well, relatively speaking [2].

> It’s not the only one being used. Local governments have their own playbooks, including Chicago, which honed its plan as part of a federal drill last year called Crimson Contagion that imagined a viral pandemic jumping from China to Chicago, then sweeping America.
> Chicago’s health commissioner, Dr. Allison Arwady, said the city made 2019 “the year for pandemic planning,” modeling various scenarios to see how the city and its hospitals could manage.

[1] http://www.dph.illinois.gov/sites/default/files/publications...

[2] https://www.chicagotribune.com/coronavirus/ct-illinois-pande...
There’s a fantastic episode of Hidden Brain that discusses research on the placebo effect itself. You should check it out!
Military and law enforcement personnel tend to be pretty high up in the current hierarchy due to corruption and abuse of power i.e: they have easier access to food, for example. Not sure how that applies to the Navy, though.
Aerosol emission, superemission during human speech increase with voice loudness
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Historic Dishes Born from Tough Times That You Can Make at Home
I think this is a pretty succinct counterpoint. I especially agree the sunk-cost of investing time learning a framework isn't something to take lightly.

The only thing I'd counter to this with is when I see this approach taken, an informal "framework" of sorts tends to evolve naturally. First you write something that handles the routing, then soon you want to organize the code the route endpoints call, then you layer on the authentication at the top level request handling area, so on and so forth. Over time, as new requirements come in and new people work on the project, more and more patterns, conventions, and library are added to the codebase - pretty soon all that "glue" code meant for interfacing with libraries is reaching or exceeding the complexity of a framework based codebase (except your codebase probably has less documentation for things like conventions and patterns than a framework would).

That said, I don't think it's the wrong approach especially when the scope of the project is limited and/or there are ways to manage feature creep (e.g., frontend only, limited lifespan, internal facing apps, etc)
It’s an onsite job but all of the employees need to work from home until the COVID-19 situation in Thailand gets better.
He knows. He's the author of https://mithril.js.org/.

It's a person well-steeped in the theory and benefits of declarative and functional programming taking a step back and looking at the supposed enemy with fresh eyes and a deeper perspective.
>You ideally want to take measures to reduce the likelihood of a given recipient seeing anyone else's copy and thus having a chance to spot the variance, but there are ways to do that

How, exactly? If you know someone else received what you believe to be the same document, what's the disincentive?

Is it mostly a matter of attempting to not give away any indication of who else may have received it, so that no one knows who could be a candidate to compare with? Or including some amount of explicitly-marked data specific to the recipient which they somehow would have difficulty censoring before sharing?
This has no bearing on the tests of this new drug, but it's worth noting that the best prevention is getting ticks off of you quickly.

I know this because I live in a very tick infested area (Ozark Mountains) and very few people who've grown up here in families that have lived here for generations get lyme disease. I don't personally know anyone who has.

Since I was kid in the `60s, and long before that, parents here did "tick checks" every evening. After calling us in mom's would strips us little kids down naked and pick any off they found and demand the older kids do it themselves and it becomes a habit. So does being aware. I mean, I don't ignore it when I think I feel one on me and I'm always aware there might be.

I'm 61 now and I've been bit more times than I can count, but I still make a point to do a tick check every evening.

Check out this video I made a couple years ago. They can get thick here...

https://youtu.be/TFVDv8swzxQ
They should have told the truth.
“Mask help but we don’t have enough of them. We need to reserve the few we have for doctors and nurses. People should use diy masks until we have more. It’s not perfect but it will still help to flatten the curve.“
It's planned. Although note that DERP only relays the encrypted wireguard packets. All we see is "please send this ciphertext blob to pubkey X", i.e. exactly what any router on the internet sees.

Still, for latency and compliance reasons, it makes sense to allow companies to operate their own DERP relays, if they want to.
Unauthorized access to cameras in Safari on macOS and iOS
Ok.

I'm not convinced at all, we'll simply have to agree to disagree on that.

And I'd love to see the codebase of a JS app that completely bans the "function" keyword. Any links or examples?
Yeah, and so did banks, and so did airplanes.
> As any small business owner knows, there are costs that you have to pay regardless of whether or not there’s work. For us, that includes a bank loan that’s killing us, vehicle loans and insurance, employee health benefits, commercial general liability insurance, workers compensation premiums, utilities, and mortgage payments. Before I fuel up a single truck, cut a single paycheck or buy a single pallet of materials, I need CAD$8,134 (about US$5,800) just to pay these costs.

Most of this business's cashflow problems are seemingly due to debt, which is somewhat orthogonal to "Randian ideology". Libertarian thinking is actually more associated with hard money and the Austrian school of economics, rather than the Keynesian debt-treadmill that is currently binding up. If this business were asset-positive, health benefits and utilities would be the few remaining costs when work shut down.

Tangentially as a libertarian I was actually hoping to glean something from this article to help me understand why the plague suddenly has a political party. Alas.
I can't go that far. What country are you from? I would have said the second syllable of "refrigerator", and the first syllable of "Frigidaire", both obligatorily rhyme with "ridge". There's no alternative.

"Frigidaire" should only really differ from "frigid air" in terms of prosody.
jitsi meet should allow it.
free. open source.
university could self host it too...
I don't like how she is referred to as a "woman", as by now, we all know that there is no such thing as "gender". Why can't it just be called a "person"?? Seriously people, this is the 20th century, ok.
NVC is just a tool. There are a number of them that accomplish the same or similar things using similar techniques and principles. Fundamentally, they are just tools for someone who actually wants to move the conversation forward. There are people who abuse the language for manipulation, and it comes across as insincere because they aren't actually trying to solve the problem at hand. I can name a few from my own past. NVC doesn't make people seem more or less selfish than they already are.

It's sort of like a programming language. It won't turn a shitty programmer into a good one, but it will turn a good programmer into a more situationally effective one. The hardest part isn't learning the programming language, it's becoming a better programmer.

The first lesson in the book I learned from, Crucial Conversations (https://www.amazon.com/Crucial-Conversations-Talking-Stakes-...), is to recognize when you are becoming emotionally driven (angry, defensive, etc.) and to step back from it. Another key lesson is to focus on identifying and solving the collective problem - the key point is that in the vast majority of cases, especially in the workplace, there is a formulation of the problem such that everyone is trying to solve it, but they are just disagreeing on how to approach it. In my own experience that's been consistently true.

These are both introspective processes of first getting yourself into the right mindset and then employing the communication tools. Learning to first be generous to other people was the hardest and also the most crucial change, whether or not I had communication tools to go with it.
Got Root?
I believe that most discussions about the placebo effect are muddled by whether regression-to-the-mean effects are included or not. [1]

When one is comparing a treatment with a "placebo", it makes sense to include "regression-to-the-mean" effects, since you're obviously looking to do better than that with your treatment.

However, when people ask "What are the biological causes of the placebo effect?", they should really be excluding "regression-to-the-mean" effects since there's no causal link between the "placebo treatment" and the regression part of the outcome.

If one looks for a placebo effect and EXCLUDES regression-to-the-mean, the effect sizes tend to be small to nonexistent, which makes discussion about their physiological causes a lot more shaky.

[1] http://www.dcscience.net/2015/12/11/placebo-effects-are-weak...
Came here to say this. This writer is clearly projecting her own opinion of what an ideal society looks like into the past. People usually do this as a way to convince people of why their world view is correct ("this is how people used to do it!"). In this case though, it is blatantly wrong.
The “Hello, World!” of Genetic Algorithms
sci-hub is an even more amazing resource