skysight-inc/HackerNews huggingface dataset:
> The downvotes on your post demonstrate the left-leaning nature of this site.

Not really. If you post something that certain people dislike for whatever reason, but which is unremarkable to others, the votes will never break even; you will not get enough upvotes from the latter group to make up for the former. (Even given the fact that not everyone can downvote.)

Whichever group's buttons you push then makes it seem like the site is overrun with that group. E.g. an atheistic comment might enrage theists, but to atheists it might just be "meh". Gee, what's with the downvotes? Boy, this site is just a haven for religious zealots!

I can't even begin to speculate about the grandparent comment. Maybe some users simply found it insubstantial? Shrug.
He says "If it does work, it‘s not as good as you hope it is" and "STUDY THE DRUGS!" What he doesn't say is "lovely natural experiment" and "GREAT Stuff".
I was surprised when I ordered from Staples.com a week or two ago. They have a top-tier e-commerce experience, fast shipping (I think my free one-day shipping was a temporary quarantine thing), and they seem to be better at packing than Amazon.
Toy Path Tracer in WebGPU
> In this study, conserved domain analysis, homology modeling, and molecular docking were used

In other words, they haven't actually done any experiments.

> The results showed the ORF8 and surface glycoprotein could bind to the porphyrin, respectively. At the same time, orf1ab, ORF10, and ORF3a proteins could coordinate attack the heme on the 1-beta chain of hemoglobin to dissociate the iron to form the porphyrin.

Haemoglobin is inside red blood cells. If you think these interactions are happening, you need to explain how you think the viral proteins are getting inside red blood cells in sufficient quantity to significantly screw up the haemoglobin.

I don't think red blood cells even express ACE2, the receptor the virus uses to enter cells.

If viruses did somehow manage to enter red blood cells, they would find that there is no transcription and translation machinery (red blood cells aren't really cells, psych!), and so they won't be able to make more of their proteins - the only things doing any interacting will be the scant handful of proteins that the virus particles brought with them.

Even then, the paper is really unclear on the details, but i get the impression that it is the extracellular domains of the envelope protein and surface glycoprotein that are being modelled. When a virus enters a cell, it does it by fusing its envelope with the membrane of the host cell, which leaves the extracellular domains of the viral membrane proteins on the outside of the host cell. Which is not where the haemoglobin is.

I think this paper is absolute nonsense from top to bottom. What am i missing?
The US is well versed in "the lesser of two evils"
one-to-one (no login required, just a shared room name), no rankings, includes video chat. Simpler and more personal.
AngelList lays off a number of staff and cuts executive salaries
Yes - it seems like Tucker Carlson was the person who convinced Trump to change his mind[1] and he deserves credit for it.

I wonder what it was that convinced him when many of the people he deals with day-to-day were of the complete opposite view?

[1] https://www.thedailybeast.com/tucker-carlsons-monologue-prom...
The hypercard stack translated (transcoded?) to HTML here: http://www.streettech.com/bcp/
> There has been confidence all around from seemingly credible sources - acting on too early and thin data about what measures were effective or non-effective, many of which have been reversed in the last couple of weeks.

This is true. In late February/early March there was a medical doctor who appeared in several local news segments here in Seattle. This doctor quoted a very misleading statistic about your chance of catching it ("you have a 0.5% chance of catching the virus").

I was intrigued by this obvious falsehood, and saw that it was also featured in a memo from one of our local hospital systems. Where did they get it from? A CDC study.

That CDC study looked at the first handful of patients to have confirmed COVID-19 in the US (all travel related) and traced their confirmed contacts. Sure enough - 0.5% of the contacts traced within this group acquired the virus.

Extrapolating this study to suggest that one's chance of catching the virus in the community, 6 weeks after the study was 0.5% was just a monstrous abdication of responsible communication.
In court they can do a class action, so little reason not to.
I mean, most of the Democratic candidates supported abolishing mandatory forced arbitration (the SCOTUS decision). Here's Bernie's policy [1].

[1] https://berniesanders.com/issues/corporate-accountability-an...
Have them look at bocker (docker-like in ~100 lines of bash).

It makes it very clear what docker is, and isn't.

https://github.com/p8952/bocker

Specifically, the bocker_run function: https://github.com/p8952/bocker/blob/master/bocker#L61
It's not reductive and defeatist to point out that the global warming issue has a tragedy of the commons aspect, on both personal and national levels, which could hardly be more different to the current pandemic.
Not very exciting, but I’ve been learning and using vue for a new side project.

The side project itself is essentially a platform to enable post-split parents co-parent effectively.
PSA: The game broke my laptop's speakers in 10 seconds.

I'm grateful that my laptop speakers are easily serviceable.
I think you just made a single bit of DRAM. It's surprising how long charges can stay around given suitably dry climate and insulators, and LEDs don't require a lot of power to light up either. A TO-220 package suggests a power transistor, so it will have substantially more gate capacitance than a typical logic-level one.
Apple has engaged in active development, not just passive sales

https://www.reuters.com/article/us-usa-defense-tech/pentagon...
Always Be Commenting
I mean that each unit in the military has some general orders on how to proceed in their mission, but the commander has a lot of flexibility. That true for the squad the same as for the platoon, they're just different sizes. The work gets done efficiently because there isn't the need to approve each action with the next level up, but often in business they don't trust the low level manager to make those decisions.
> This is a bit crazy. I have never had a place tell me to call the manufacturer.

I bought a stand mixer from John Lewis, a British department store with a (arguably fading) reputation for better service, its own 5y plus guarantees, etc.

When I needed to call ok that guarantee for a replacement part, I had two months of email run around before getting a reference number and phone number for the manufacturer's UK distributor.

It was a further 3.5 months of calling the distributor, being promised it was on its way, and on occasion receiving the wrong part (once) or no part (twice).

When I complained to JLP about the experience, that I didn't feel I should have to contact some third-party distributor/wholesaler for assistance in a claim under the guarantee agreement with itself, I just got fobbed off with an email telling me to phone the number their colleague had already sent me, as if I hadn't read the email - comically ironic since it was clear from my own complaint that I had; so it was my email that hadn't been read.

Anyway, rant over. Moral: if you're in the UK, JLP not what it was, think twice for purchases where guarantee relevant; relevance: I only very thinly veiled my description of how much better its 'online competitor' is in handling returns/replacements.

John Lewis: 5.5 months emails, calls, waiting for a £20 replacement part.

Amazon: 2 minute chat and until next day wait for a whole product (~£150) replacement due to defective (~£10) part. Original to be returned ~at leisure.

Honestly even if Amazon's a few quid more expensive (at that price point), which it typically isn't, I'm at the point where I choose it just because it isn't painful when it doesn't go completely smoothly.
I wish languages more clearly distinguished between functions that produce values and functions that have effects (and ones that do both, but discourage that).
Even better, show your local/remote branches in most-recent order and interactively pick the branch to switch to using fzf:

https://github.com/kbd/setup/blob/f3ebd5ef2bc8a010357b574c02...
Fortunately good judgement is an occasional human virtue which also cuts across party lines.
No, Instagram is missing the fundamental focus that makes something a "check-in app", i.e. a data presentation hierarchy where "I am at (specific place)" is on top. Instagram's top level of data is "I have picture".
For those of us who don't have APS access, there's the preprint: https://arxiv.org/abs/2002.11761
In England, we call Stonehenge a monument:

https://heritagecalling.com/2016/10/10/im-sorry-but-what-is-...
> can always result in a cheaper device.

^^^^^^^^^^ oxymoron alert
thanks for the info, wasn't aware of the historical context.
I haven't seen any evidence that (Xydroxy)chloroquine alone directly inhibits anything to do with the viral replication. The closest thing that I found is that Thymoquinone inhibits Mouse coronavirus replication and is generally protective of lungs:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933739/
https://erj.ersjournals.com/content/50/suppl_61/PA4935

Chloroquine is an antipyretic and relieves symptoms like fever from diseases like Malaria and dengue.

Chloroquine stops the inflammation from going out of control, which a good thing during an infection. But if you take it when you don't have an infection, it could stop you from detecting viruses in the first place.

The paper I cited in the previous comment mentions that Chloroquine is a TLR7 inhibitor. TLR7 is a receptor that senses of single-stranded viral RNA.
https://www.sciencedirect.com/science/article/abs/pii/S01663...
That's an interesting point-of-view. I was also worried and had to search in their Slack channel. This is what they have to say:

"so specifically to lock-in: right now, no one concerned about lock-in is going to have a good experience on dark. We don’t have the resources to address that need, but at some point we will be in a company position to deal with the lock-in question. Our plan is to give you tools and resources to move off Dark if you want to"
VC's do it all the time.
Customizable charts of Covid-19 Data
I've got a sort of morbid fascination with the COVID denial scene on Twitter. Every few days I check out this guy Bill Mitchell (@mitchellvii, 500k+ followers), and it's been interesting to see how he's adapted. This tweet captures it well:

https://twitter.com/classiclib3ral/status/124681200696072601...

Not sure if Paul is looking at this kind of thing, but from this essay I'm not sure he really grasps how fractured the media consumption landscape is at the moment. The tide hasn't come out from under many, if any, of these people. Their position is as strong as ever. They have their own moons, their own oceans and their own tides.
Hi! Krustlet maintainer here.

The idea behind the project is to run WebAssembly modules in Kubernetes. You would have to compile your Python script to WebAssembly before it could be executed.

If your WebAssembly module complies with the WebAssembly System Interface, Krustlet can run it.

It's important to note that the WASI standard and wasmtime are still under heavy development. There are some key features (like networking) that are currently missing, but will be made available in future updates.
https://nowtoronto.com/lifestyle/real-estate/airbnb-hosts-co...
I don't think your slavery example is really a counterexample... those children are new members. The linear scale is about people to productivity, not 'cost of a new worker' vs productivity.

Also, the military is different; it is not really trying to produce anything new, so isn't the same type of work.
Banach–Tarski Paradox
This is exciting. You can do VHDL synthesis with the commercial version of yosys now (uses the Verific commercial parser). Will be great to have an open source solution.

GHDL is written in Ada, if you have ever wanted to see that in the wild. It looks like this is in C++, which will probably make it easier to get contributions
Toronto Airbnb hosts ponder selling as bookings vanish
ordered a single speaker once and they contacted me to make sure i didnt want two, which i actually did... really next level customer service
This is excellent. Forced arbitration clauses are fundamentally unfair to consumers. See this older article to understand why:
https://www.nytimes.com/2015/11/02/business/dealbook/in-arbi...
My wife, two of her brothers, their spouses and obviously many of their collective friends are public school teachers in the US. The teacher's union in our state is largely a spineless organization that will protect the points they negotiate into a contract but leave legitimate educators high and dry when it comes to real issues. It's one of the worst unions that I've had the occasion to see up close and personal...and I'm a former member of the Teamsters.
Ok, I've added that part of the text to the title. Thanks!
What I would like is download the data as CSV or SQLite database, and then I can make the charts on my own computer.
I think you're a little too hung up on the audience metaphor.

> Perhaps confusing battles between "freshwater" Chicago macro economists and Ivy league "Saltwater" theorists could be best understood as happening within a single "orthodox promotion" given that both groups suffered no injury from failing (equally) to predict the recent financial crisis.

The Kayfabe element is that two "competing" schools of thought are primarily concerned with protecting the shared status of "orthodox" economics over outside theories.
Reminds me of this epic discussion between KirinDave, Ryan Dahl, and Aphyr: https://news.ycombinator.com/item?id=4306241
Live design of reactJS native app build
It's probably correcting people's typos, as well as saving a crap-ton of money this way (search results are undoubtedly cached).
It is a tough one and yes, here in Germany I would expect far most developers to understand enough English to use English tools and documentation. (Exceptions exist, notably with old technology like Mainframes)

In other countries like Russia or Japan I noticed, as an outside observer, more reliance on translations.

When translating a complication is the degree to which one does it. There are terms which can be translated and some where it becomes weird. In some parallel comment "pull request" was mentioned. Translating that certainly becomes weird, but translating "file" as "Datei" is well established and - when translating - expected.
Because if you have an input on the right and you combine this with other digital logic you are going to end up with crossed wires backtracking to that input on the right somewhere, I would guess.
If you can keep a pump running, then you may as well just use adiabatic cooling (gas under pressure gets cooler when released) to keep your stuff cool. That’s how your fridge works!
Actually, China was thought to have covered it up because the whistleblower originally sent a message[1] to a WeChat group of his, telling group members that 7 people from the wet markets had been diagnosed with SARS. The government had no idea what it was and I'm sure nobody in the world knew what it was at the time, hence how it's a novel virus.

[1]: https://mmbiz.qpic.cn/mmbiz_jpg/jvumSxUR3OrjfcgXFibaich6y6Z6...
The reason it is not usually drawn that way is it is a cardinal sin to draw logic gates 'backward' on a logic schematic. It is a schematic schematic equivalent of 'goto' and makes schematics confusing to follow. For a simple inverter in a flipflop it isn't so bad, but when you are inside of a larger schematic it is better to stick with the best practice of signals flowing left to right for all symbols.

PS - For what its worth, that image has a transparent background, so when the imgur viewer displays it you get black traces on a black background.
Lots of people here are pointing to Philip Tetlock's book Superforecasting which describes these forecasting problems, and also a more rigorous, scientific approach to forecasting.

Interestingly, Tetlock's 'superforecasters' predict a 30% chance of more than 350,000 coronavirus deaths in the US: https://goodjudgment.io/covid/dashboard/

This is up from 17% on March 21
Your image appears as black on black, you might want to re-upload it or edit the URL. I could only see it by dragging it against a non-black background.

Good point otherwise on the clearer schematic!
So he came up with the idea of drinking this chemical by himself?
MBONE: The Multicast Backbone (1994)
while this is neat, the mouse input is complete garbage, but its a zero friction way to show someone the mods I guess
You forgot "Flex PTO"
Please don't propagate this. Running in a hypervisor with a possible different kernel vs running on the same kernel in the same ring as the host are two very different things. Implications of these are very different.
DIY Mask with Elastic
I strongly agree that this needs a diagram of the transistors
After seeing it develop in my wife, and later myself, I can confirm that it “appears like malaria” in that in comes in waves (much like a blood disease like malaria). There could be some truth to this, but it could also be personal bias seeing a pattern that isn’t there.
US death toll surpasses 10k
The abstraction muddles the performance, security etc. impact of these two models. Not knowing them is going to be bad in the long run. Not everyone is a web dev.
In their defense, developing content for a classroom is a shit-ton of work. Flipping that over to Internet-only is going to take some time. If they are just sitting at home getting drunk and trolling facebook that's one thing, but it's going to take a couple of months for teachers to effectively pivot to a mode of teaching that they've never had to do. Until then you're just going to see a trickle of work even from the best of them b/c they are going to be focused on trying to develop a game plan to close out the year.

My wife taught K12 for 12 years and then became an instructional coach teaching teachers how to teach. There's a shitload of work if you want to do it right, and at least half (in our district anyway) will stretch themselves extremely thin to do so. Half of the rest are 9-5'ers and the remainder are shitheads.
In the future, where every stupid little software program runs in the cloud, and private ownership of bits is history. My wallet dies by death from a thousand cuts and I have no ability to peek at game internals or tinker with data files
How to have good sleep is also a bit of a mystery for me. A fresh breeze, sunlight, de-congested nostrils, lack of alarm, and relaxing ambient sounds like chirping birds and people living their lives in the distance seem to help, but ideal conditions aren't always available.
Hey, Been a Brief Time
Google to help NY fix stressed unemployment system
Out of curiosity, and because I'm a Canadian out of the loop with respect to American news networks, how can there be news being at ends with each other? That's something I have difficulty putting into perspective (referring to the Team CNN vs Team Fox comparison)
I found the following videos helpful in explaining how to apply sterile technique to processing groceries.

Many are just using gloves or masks as a talisman to ward off the corona but not appreciating how these PPE items, when used poorly, are likely worse than having no PPE, a few items for sanitizing, and awareness.

https://youtu.be/sjDuwc9KBps

https://www.youtube.com/watch?v=0wTWrQoDhPw
> The linear scale is about people to productivity

According to the article, the scale is about "hiring" to "work capacity" -- the author specifically points out that productivity is another ballgame altogether. (FWIW, I'm not sure what "hiring" means in the context of slavery -- I suppose a Roman-style post-war enslavement could be one equivalent.)

> Also, the military is different; it is not really trying to produce anything new, so isn't the same type of work.

Yeah, this is a good point. The military is not as "creative" as your run-of-the-mill corporation and, as such, probably doesn't need the coherence.
Hugely contentious statement. People still play the original Quake competitively. It's still one of the most thrilling and intense multiplayer FPS experiences. There aren't many games that are as fast or have a physics engine that can be so impressively manipulated.
Not sure what your point is

This seems like basic risk management.
You'd probably like this. Compare.

New York Mayor Bill de Blasio on Mar 2nd.

https://twitter.com/germanrlopez/status/1247210000155643904/...

San Francisco Mayor London Breed on Mar 2nd.

https://twitter.com/germanrlopez/status/1247210000155643904/...
And I'm a dev "doing cool things" with namespaces / cgroups.
Oops. Just a typo. I meant baseline chance of 30% of not getting it. So I figure, with precautions, you have a more than 30% chance of being in that 30%.
> No. A good Bayesian should be able to come to decisions like, "I am 70% confident that Osama bin Laden is in that compound."

That's not a decision though. That's an assessment, what I would put in the same category as predictions. A decision would be whether or not to bomb the compound.

Your post seems to miss my point, that predictions and decisions are very different and one can be uncertain about predictions while being certain about decisions. For example, I completely agree with this:

> It is very rare for a good Bayesian to be absolutely confident of any prediction.

Here's a simple example to think through the difference. You have a sophisticated weather model that predicts 40% chance of rain today. You hate getting wet, so you take your umbrella. In fact, you would take your umbrella even if the chance were only 10%.

So you are really uncertain about whether it's going to rain (your forecast), but absolutely certain that taking your umbrella is the optimal decision given the information at hand.
You're leaving out a lot of details and what a spin that was.

The Chinese government was informed and chose to cover it up.

https://www.axios.com/timeline-the-early-days-of-chinas-coro...

https://nypost.com/2020/02/29/china-officials-knew-of-corona...

https://www.vox.com/2020/2/10/21124881/coronavirus-outbreak-...

https://www.npr.org/sections/goatsandsoda/2020/02/08/8037667...
Canva | Full-time senior hires | Sydney | Permanent, Onsite, VISA, Relocation.

https://about.canva.com/careers/

We're taking on the world of design and content creation with a product loved by millions around the world. If you're a founder have a look at the tool.

Recruiting across the business - including Frontend, Backend and Fullstack Engineering, UX Design, Digital Design, Product Management, Growth, Data Science and more.

Engineering stacks: Backend = scalable Java services, Frontend = React + TypeScript, iOS = Swift, Android = Java & Kotlin, Data = Python.

Feel free to ping me on crowe[@]Canva[.]com for a referral, any questions on what life here is like, and the cool things we're doing.

Permanent & onsite roles only, full relocation provided. Initial onboarding remotely is possible.
Unfortunately McMaster-Carr won't deal with Canadian companies they believe could be associated with the cannabis industry "due to US Federal Laws". I've been at two companies where we've placed an order with them, then had it immediately cancelled. Only after following up did I learn the reason.

When I tried to re-order through my personal company (not in any way cannabis-related) I was told I'm not a big enough company for them to deal with (and they cancelled the order).

From a CAD/dimensional standpoint, their website is a goldmine. I just wish they would take my money.