I have a strong belief that there definitely are lifestyle changes you can make in order to lower your chances of getting Alzheimer's, and there is some support for them, although they need more research in order to confirm the exact magnitude and effect. Some of the ones which I believe are worth taking a closer look at are listed below:

– Regular exercise may delay Alzheimer's in those at high risk of disease: https://inews.co.uk/news/health/regular-exercise-delays-alzh...

– Dr. Dale Bredesen Protocol: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712873/

– Control Hypertension: https://www.fightaging.org/archives/2020/01/controlling-hype...

– DASH diet: Healthy eating to lower your blood pressure: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h...

– Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671587/

– Alzheimer's Disease Is Type 3 Diabetes–Evidence Reviewed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/

Some good reading and support for the herpes / viral hypothesis is provided below:

– Alzheimer's risk 10 times lower with herpes medication: https://www.medicalnewstoday.com/articles/322463

– Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection: https://www.cell.com/neuron/fulltext/S0896-6273(18)30526-9

– Another interesting link: In India, people have a much lower incidence of Alzheimer’s, and one of the primary reason is usually attributed to Indians eating a lot of Turmeric. It turns out in fact that one of the primary compounds in Turmeric is Curcumin, and its shown to help against herpes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668156/

Our current issue today is the we wait for things to go wrong and then we attempt to address them instead of trying to find the root cause and proactively trying to tackle the problem early. At the same time, finding the root isn’t necessarily easy, and performing longitudinal studies that would confirm a lot of these hypothesis would also be extremely difficult to implement, so I don’t necessarily have the solution to addressing the problem.

Some factors which I may have already listed above and which I strongly suggest you implement if you do want to lead a healthier life and prevent dementia are provided below:

– Daily exercise (both aerobic intertwined with strength training).

– Daily fasting (eating in a 4 – 8 hour window along with periodic 2-3 day fasts).

– Healthy diet: Stick to a mostly plant based diet. Eliminate high-glycemic index simple carbohydrates and replace them with healthier low-glycemic index choices (i.e. include lots of high fiber foods along with low GI fruits and vegetables). Replace bad fats (artificial trans fats and saturated fats) with good ones (fish, nuts, olive oil, avocados). Avoid highly processed foods and foods with added sugar.

– Take a teaspoon of turmeric daily (with black pepper, which increases its absorption).

I remember reading how Japan went from producing products which were garbage when it comes to quality and transforming themselves into becoming the kings of quality within quite a small time frame. The way they did this is through simple focus on root cause analysis and transforming their manufacturing processes from being reactive to introducing proactive measures and always focusing in on finding and addressing the root cause. I really wonder when medicine will start taking the same approach. It wouldn’t be an easy transformation, and the incentives today also aren’t exactly aligned to make this viable yet, but hopefully we see some changes within the next century or so, since the evidence to me seems to indicate that we could get a lot further by taking a look at lifestyle factors rather than the reactive measures we employ today.