skysight-inc/HackerNews huggingface dataset:
Curing disease. Not just the current pandemic, but cancer and everything else.

There are only 70,000 cancer researchers in the world. You could 1000x this and still only be 1% of people. 1000xing isn't likely to create 1000x the progress, but maybe you could hope for √1000x. So the progress of 31.6 years happens every year.
For the last few years I've had the Feynman Lectures [1,2] sitting in my queue, and I've finally gotten around to starting them in the last week. It's been a fun ride so far, and it's been nice to have the time to digest the lessons without having to run off somewhere. It's also helped to have the MIT OCW lectures as a reference [3], in which I found a book title "Quantum Mechanics and Experience" [4] that I started reading as well and so far has been the most down-to-earth introduction to Quantum Mechanics that I've found. I highly recommend it.

[1] https://www.feynmanlectures.caltech.edu/

[2] https://www.amazon.com/Feynman-Lectures-Physics-boxed-set/dp...

[3] https://ocw.mit.edu/courses/physics/8-04-quantum-physics-i-s...

[4] https://www.amazon.com/gp/product/0674741137/ref=ppx_yo_dt_b...
It's kind of frightening to think of the broader economic impact it would have on the whole real estate market if Airbnb went belly up. Aren't there a ton of cases where people are mortgaging multiple homes and paying them off with the revenue they generate? That cash just dried up over night and there doesn't appear to be any incoming federal support.

Edit: Look, I'm all for affordable housing, but when viewing this within the context of a looming recession and potential financial crisis I can assure you that the last thing you want to do is add in a potential amplifier to a housing market crash. Houses may get cheaper, but everyone is going to suffer in very difficult to imagine ways. Corporate debt markets are looking scary as hell right now. If you threw a housing market meltdown at it right now, we could easily be looking at something much much worse than what we saw in '08.
Agreed. In my opinion, the best way to make admissions more fair is not to eliminate the SAT but to eliminate score choice.
That assumes outrage is motivated primarily by flawed systems and not the psychological and social benefits that accrue to those who express the most outrage. It may also be true that outrage is not the best way to solve systemic problems.
If you can get new work (another client), charge more for it. If you have a cheap client, get rid of them as soon as possible,

Cheap clients are bad clients. If you charge more, you will be more respected. You will have more and better clients. And you'll make more money. :-) Price acts as a signal. Think about how you would buy something that you didn't know about, say wine; in the absence of other info, you would equate the higher price with a better product.

If you charge less initially ("until you get your funding, etc") when you charge full price the customer will not feel grateful at the deal you gave them. Instead, they will feel ripped off by your full price. Charge full price or work for free.
I didn't see any. I guess something caught it (origin/pihole/bypass paywall)
Agree, and that's kind of my point. Being "fully funded" wasn't the problem--it was hubris/mismanagement.
It’s already commonly used as both treatment and profylactic (in healthy risk group patients) for viral pneumonia. Why it works for I think is still not entirely clear.

Being an antibiotic is also convenient because many times you would also get antibiotics to prevent a secondary infection from bacteria.

It’s not exactly a miracle cure (like an antibiotic is against a bacterial pneumonia), but doctors have few tools when it comes to viral pneumonia, so even something that helps a little is welcome.
This. I’m a college freshman and took the SAT and PSAT when in high school. I’m also not a minority. While I and my parents could have afforded the expensive prep courses the students around me were taking , I decided to skip these and focus purely on solo prep. Across the PSAT and SAT, I spent a total of $50 for my prep–a $35 dollar, thick book of SAT problems, and a $15 PSAT prep book. Technically, you don’t even need to buy these books—many libraries offer the books to borrow for free.

Just going through those books and drilling incessantly on weekends and in my free time was enough to get me a 1520 on the PSAT (the max score, which helped in gaining merit scholarships, which is the reason I go to school for free right now), and a 1540 on the SAT (99th percentile). I also used Khan Academy extensively, which provides free prep sponsored by Collegeboard.

In my opinion, prep courses are just a means for unmotivated students to put in the same amount of work as a highly diligent, self-studying student. There’s plenty of free and relatively inexpensive resort resources out there nowadays, it just requires time and attention (which sadly a lot of my generation doesn’t have).
It is definitely true that you can build a career without a college degree. However, I don't believe this is the main point for college. Personally, I went to college solely based on an interest in learning. I can't imagine learning astrophysics (my degree) to the same level of understanding without the community of peers and mentors colleges provide.
What? You could make a case for "comparing apples to baskets that contain apples", maybe. But you may notice that eating an apple and eating an apple that came out of a basket are the same task.
Truth be told: the culture of those institutions is based on extremely synthetic virtue-signalling and superficial values and is very far from being meritocratic or open to social mobility.

This might be great for rich kids, though in case you are ambitious, clever, gritty but come from not-so-privileged background (not necessarily low-class or third world - just temporary economic turmoil is enough) - you are going to hate every single second you spend there with all your heart.

So maybe this way it is a win-win in the end. The aristocracy get their titles and the plebs their opportunities for self-realisation. No harm done.
Visual Transfer Learning for Robotic Manipulation
Windows if full of weird names for it's subsystems if you look closely.

The old installer had "Windows Executive" and "Human Interface Parser" as installation items that always had my head scratching
As an "old people", I thank you for your consideration and concern.
Data from an Italian study:

https://www.bloomberg.com/news/articles/2020-03-18/99-of-tho...

Median age is 80.5. That's actually near the life expectancy of an Italian male.

99% of fatalities were among people with a prior illness.

About half of the deaths were people suffering from three or more other illnesses.

To put it very bluntly, a lot of the folks dying from COVID-19 were already dying. COVID-19 is the straw that broke the camel's back.
Won't each college having to have their own test lead to many/most colleges, especially smaller ones, finding it easier or more cost effective to purchase their test from a central source, leading to some large College Board-like company making exams and a prep industry for that standard exam?
It will be interesting to see what happens to all these VC-backed companies that have been losing money for years and are still not profitable.

When the VC money runs out not even government bailouts will help. Helping money-losing companies to lose more money isn't in the interest of a government unless they are essential to the rest of the economy or national security.

Maybe the bay area will be hit much harder than other companies.
Is the evidence really that suggestive that college prep makes such a huge difference? I am skeptical, it seemed pretty easy to just study from the blue book.

Probably the biggest way to stop the affluent from taking advantage of the system would be to eliminate school choice.
They're not back yet. The back end is pumping goods again, but the receiving side is crashing, sending demand shock waves upstream.
I created this both for now and the future.
My Maybe Crazy Corona Virus Viral Internet Ideas
If this theoretically erupted, what would the impact be? Extinction level?
Our new reality is getting scarier.
Same story from the original source, previously on HN:

https://news.ycombinator.com/item?id=22306801 (572 pts, 165 comments)

https://news.ycombinator.com/item?id=22303956 (49 pts, 10 comments)

https://news.ycombinator.com/item?id=22352501 (15 pts, 1 comment)

In-depth video of the build:

https://news.ycombinator.com/item?id=22519476 (6 pts, 0 comments)

Related: someone converted an old rotary phone into a cellphone:

https://news.ycombinator.com/item?id=9610509 (222 pts, 61 comments)
So are you just gamifying users collecting a large data set for you? I think that is genius.

What are you doing to encourage engagement? Why would one keep playing? Is there something other than just seeing their score go up?
Can someone with a better knowledge explain to me what's going on here?

The number of infection is not relevant, shouldn't the number of severe cases requiring hospitalization be the metric to care about the most?

It looks like this number is drastically lower.
I think poor reporting, governments is taking more control measures
Maybe if money weren't an obstacle for getting a good education, then we could actually have the best and brightest going to schools like these instead of just the most well-prepared because of family money and the advantage that wealth brings.
I totally get why people delivering great content want to maximize their readership this way, but I've never read an article on that site before, so how would I know if its worth giving my email?
The subreddit dedicated to this song maintains a spreadsheet of possible leads and sound-alikes.

Personally, the first thing that came to mind when I heard the vocals was Type O Negative. Sounds a lot like Peter Steele, but I'm sure a lot of vocalists at the time were going for that style.
Here's a short paper on it [pdf]: https://www.jstage.jst.go.jp/article/ddt/14/1/14_2020.01012/...

Not many details, just that it worked better than some HIV antivirals. Still, worth ramping up production of this in advance of trials. It's a surprisingly small and simple molecule.
Ask HN: How will the world change after the global coronavirus pandemic?
What future scenarios can we hypothesize? how will people behave in everyday life? how will the scenario of travel and consumption change? I am very interested to hear your opinion.
I also wonder this, isn't Airbnb your typical venture capital company.
They’re losing revenue due to the massive amount of recently cancellations.
"One that I find particularly amusing, for personal reasons, is the idea of complexing zinc ions...So yeah, I can at least believe that these things complex zinc, for what that’s worth."

Not sure if this statement supports or refutes your theory; I'm inclined to believe the latter.
The threshold for finding of “unreasonable” is surprisingly lax in normal times. It’s no doubt going to be more lax now, especially if the discrepancy was remotely plausibly COVID-19 impacted (inability to use your normal preparer, access your mail, whatever).

I file the 4868 literally every year; I’ve never had any estimate even questioned, let alone overturned, despite sometimes being off by mid-high 5 figures (usually over, sometimes under).

The IRS seems content as long as you’re showing any reasonable intention to comply with your obligations. Everyone is afraid of them because of their power. That’s sensible. My experience (including two audits, one a TCMP audit) is that, while they move at government speed, they are quite reasonable and even helpful to deal with.
As I understand it - it interferes with mRNA transcription. Given that COVID-19 is RNA that may be useful.
Makes me wonder if they will start to offer "trip protection" or the like. The economics of it checks out.
I'm not trying to show percentage of infected, but the spread over time. And it's spreading a lot faster in the US and/or we are testing significantly.
You also have a few close ones coming up this weekend.

https://www.news18.com/news/tech/four-new-asteroids-are-appr...
How to people get it? I assume it’s a prescription drug everywhere? Is everyone friends with a doctor or is my expectations on doctors too high (that they shouldn’t prescribe something just because a patient asks for it, perhaps especially not if the patient asks for it)?
Bill Bryson's book A Short History of Nearly Everything does a good job of describing it, I'd butcher a paraphrasing. Essentially, feet of ash covering hundreds to thousands of miles.

It also highlights that this is been going on and areas bulge constantly.
The lancet article is what I've seen.

I think early on, it was assumed ARDS was the worst outcome; your lungs stopped functioning and ventilation would tide you over.

But the more we dig in, there are multiple systems failing and ARDS is just one of many destructive processes going on.

This is one of the really important data points to work out. If almost everyone ventilated will die... it makes no sense for hospitals to extensively treat this way. Give people palliative care. It directs resources away from other, more productive efforts... for example ... running clinical trails on potential treatments to PREVENT ARDS/sepsis.
Absolutely nobody find I surprising that China claims no new cases? I'm beginning to wonder if they're lying...

(For Chinese two cent army, look up tiananmen square)
And how exactly will you "dismantle it"?

People want to pay thousands of dollars to try to gain access to elite institutions. No matter what test you'll come up with, someone will offer an expensive prep course for it, because they will have willing customers.
The subject tests, IMO, are terrible. I took the Chemistry one right after taking AP (college level) Chemistry, and while I got a full score on that, I got absolutely destroyed on the subject test. They asked trivia-like questions and barely tested for actual chemistry knowledge.
Just to iterate on this, appreciate all the feedback.

There is no monthly subscription, unless you are an MSP or partner, and you only pay for each backup or migration job conducted. So if it’s a one off migration, it’s just that one off fee.

You can schedule regular backups between cloud storage as well. It also supports deltas/partial updates of modified files since the last backup where possible.

I.e. you could set up a daily backup between an S3 bucket and another provider.

Another thing to note, it also supports native SFTP, SMB and NFS in an effort to help those move off more traditional systems and infrastructure.

Once again, good discussion and really appreciating the feedback.
Respectfully, though I understand your effort to warn others, I think it is dangerous at this time to conflate chloroquine derivatives with Chloroquine. Single substitutions in biologically active compounds can cause drastically different effects including substantially different therapeutic ratios. Compare for example the various drugs in the amphetamine family (methamphetamine, amphetamine, MDMA, etc). They are not equally dangerous.

Similarly, the terrible results you report are AFAIK rare with Chloroquine. It is a well tolerated drug and if you're an older or immunocompromised patient playing Russian roulette with a late stage COVID19 infection, the minimal risk is highly preferable to no treatment.
This would not be a bad thing. Airbnb has been driving up the cost of housing in many cities.
I think it's important to clarify that that SAT is not the same as the SAT Subject Tests. The latter are being excluded, but not the former. One could reasonably argue at this point that the Subject Tests are simply redundant with AP tests.
I've been suffering badly from fluoroquinolone toxicity for 5 years. Doctors literally are clueless about it.
Visual Studio Code with iPad cursor support
Don't talk to me until I've had my morning coffee. \s

Don't talk to me until I've eaten this mug.
I am not so sure herd immunity is a goal. The idea is indeed to avoid overrunning the healthcare system, with an expectation that we can get the majority of the population successfully through the system. It's not well-known that we'll build even short term immunity, let alone long to medium term immunity.

If new cases flatline, that's good! If we can avoid everyone getting it, that's even better! If the globe can get a handle on things, we don't need to solely consider worst-case scenarios.
As someone that would like to buy a house one day, I welcome this. People owning multiple houses to rent out to vacationers that people would like to actually live in doesn't upset me at all.

If people buying houses to rent on Airbnb artificially inflated the housing market, it's just a necessary correction and federal support would be a mistake.
Who trusts these predictions any more? Lies and exaggerations non-stop. They _always_ seem to find something people cherish (cars, beef burgers, coffee, tourist attractions) that will "be the first to go unless humanity repents."
This Is Not a Recession. It’s an Ice Age.
It needs to be dismantled due to monopoly. I’m not sure how. Those are orthogonal.
A number of things this seems to do well would be pretty much impossible with standard photogrammetry : trees with leaves, fine details like rigging on a ship, reflective surfaces, even refraction (!)

Of course the output is a new view, not a shaded mesh, but given it appears to generate depth data, I think you should be able to generate a point cloud and mesh it. Getting the materials from the output light even be possible, I'm not very up to date on the state of material capture nowadays.
Isn't it equally frightening how Airbnb has contributed to the rise of real estate prices and rents?
> I think that means SAT scores don't predict success too well at all beyond a certain threshold.

Try reading about it.

https://libres.uncg.edu/ir/asu/f/Webb_RM_2001_Top.pdf

> There is another implication as a consequence of the statement "the influence of test prep, cramming, test coaches, etc. is minimal for the subject tests." That is, I first read tha[t] the students don't suffer under these conditions.

This is not a valid inference to draw; the influence of test prep, cramming, coaches, etc. is also minimal for the main SAT, but students suffer through them anyway.
Trick Makes You Immune to Illness – Wim Hof on Impact Theory
They would just switch to VRBO or a similar service.
China took about 18 days to get from from the number of cases the US currently has, to the peak of infected cases. But they had a pretty different approach to controlling it than the US did.
Cloud DeveloperDays 2020 Conference – Now Free and Online
I was thinking this the other day, it is a special type of vendor lock-in.
They're probably counting on name recognition. I'm not sure about outside the US, but National Geographic is a big name here.
Regardless, having the money needed to pay for last year's taxes sitting in the bank, equivalent to... a year or two of living expenses or so... and not having to empty it out as the world comes crashing down is kind of nice.
I've had some experience with the robotics / automation engineering side of industry. It's not easy to take super high-level automation and turn around and make it produce something else entirely.

Base / core machinery- such as a 3-axis CNC machine, or a lathe, or a saw, for instance, are fairly nimble- if you have the right cutting bits (which you probably do, considering that it's industry) you can switch from milling out aluminum mounting plates to milling out enclosures for electronics fairly easily. At this level, generally humans are responsible for sticking in the material and telling the machine what to do each time an action is performed.

Where it gets more complicated is at the higher levels of automation, where humans might be supervising the machines, but aren't initiating processes themselves- for example, there was a prod cell that I worked with that had a robot putting raw material into a mill and then removing it- humans program those arms, but then after that, it just goes, and goes, and goes. Programming those arms is generally an exercise in making sure the math works, and then implementing the job in a bunch of for loops and hard-coded / static adjustment variables and the like. In these instances, to make the cell produce something else, not only do you have to program the machine that actually produces parts, but you also have to reprogram the bot that puts and pulls from it, and you may also need to change the grip on the bot to support the new geometry.

At the really high levels, like how car manufacturing is currently, there are processes where metal blocks go in and a whole monoframe chassis comes out. Taking that and saying "I want a ventilator assembly" is pretty much insane- besides reworking the entire line to support the new process, you've got to wire everything up, test it, inspect it, make sure everything is up to OSHA standards, etcetera etcetera, etcetera.

Going from producing one thing with a high amount of automation to another that doesn't have any similar parts is insanely difficult. Not saying it isn't worth it, but it might be better to go to the factories that are already producing the stuff we need- ventilators, masks, respiratiors, tests- and seeing if there are any bottlenecks that could be removed.

The best way? Have enough stuff on hand to actually handle a crisis. Too bad prepping for a rainy day doesn't really align with maxing out dividends and payoffs.
hear hear! fuck those greedy fuckers!
Given only the thread would die, what about panics?

For example, `.parallel_stream().map(n => 1 / n)`

What happens to the `n=0` case? Does parallel_stream propagate the panic, or replace the value with a Result::Err?
Buddhist Economics – E.F. Schumacher
I live in South Carolina https://www.scdhec.gov/monitoring-testing-covid-19. You are correct testing is still low, but I don't think that data is useless. I don't agree with the notion that it 'will be too late'.

As others have said, the point of a lock down should to prevent the hospitals from getting overwhelmed, prevent ventilator shortages, etc. Nobody even knows if a preemptive lock down can 'squash' the virus. While testing is being ramped up, aren't there other ways to determine outbreaks? Can't our leaders communicate with hospitals and find out number of open beds, ventilators, an influx of patients with suspected symptoms?

It is still going to be around once we come of of hiding, whenever that is, so it's possible we are just delaying the acceleration phase and we end up with the same result later instead of facing it now. I'm not saying there is never a time for a lock down, I just wonder if my local leaders panicked and did it to early, because they didn't know what else to do?

So in my area, the hospitals are fine. People are not flooding in the doors. Meanwhile thousands of jobs & businesses are being torched. My mom is a massage therapist, and is out of work for the foreseeable future. I just think there are smarter ways to go about it.
It's bold move, but necessary to stop people going into work. The tubes here in London were still packed a few days ago, because low wage earners still need to travel in to earn and put food on the table.
They're honoring a massive amount of refunds. There's also a lot of logistical work to be done for hosts which will probably be expensive.
It helps to be advised by one of the best people in healthcare too, Dr. Howard Zucker.
> It may be good - the outcome determines if it is good.

I'm not strongly committed to the argument that it's good. A better word might be "appropriate" or "justified." The point is that this kind of outrage is very different from what we normally call "outrage culture." The implication in a phrase like "outrage culture" isn't that outrage is an invalid human emotion; it's that it's not being tuned/targeted correctly.
Because the goal of the page is to get your email sign up not to display text.
They lost close to $300M last quarter. And those were the good times.