skysight-inc/HackerNews huggingface dataset:
The title reads like judging a startup founder. I'm not sure if all the startup rules apply to governments.
Interesting. Are there any projects actively using this today?
There’s a 311 app that is technically run by the city but is effectively useless for actually effecting any sort of change
I don't think I understand the question. Generators are CMake's way of creating IDE-specific build files, and I wish that people used them instead of writing their own scripts to create IDE-specific build files from CMake.

Generators are there so that you don't get tied to any one IDE; you select a different generator when you want to use a different IDE or compiler, but your CMake logic can largely stay the same besides that.

If I were a cynic, I would say that the vendors probably don't mind it being difficult to interoperate with their competitors' products, so there's little incentive to support things like that.
Recently in DC they detected a plane that did not respond to warnings. The optical system then also detected the plane and panic ensued. Problem was the radar system was showing a phantom and the optical system saw a nearby plane and thought it was confirming the phantom.

Tldr; it's complicated

https://www.thedrive.com/the-war-zone/31222/mysterious-airsp...
I'm surprised I haven't seen this before (or if it's been around, it hasn't been more popular). In person you often show people videos and via podcasts I often hear people haphazardly trying to play videos simultaneously.
No it won't, it is time shifted. Doesn't negate the fact that there is a short term demand spike.
I uh, ... what
I think this as well. The only problem I learned about, is that there seems to be a chance of long-term respiratory damage (e.g. 20% lower lung capacity), which is as of now unlikely to be properly tracked / reported, but likely higher than the reported number of "critical" or "death" outcomes (which indeed are tiny in < 40s)
this could get extremely popular as a rabb.it replacement
This is nonsense, you don't even need to cook anything at all to eat healthy from the grocery store.

You just have to get off your ass and actually go buy perishable fresh groceries regularly and plan for the week ahead.

Laziness and convenience prevails.

If it's a lack of time, then it's a lack of time to even hit the grocery store. Which depending on where you live, if it's a food desert situation, may be valid.
Of course none of them were on auto pilot. Come back in 4 months and dine on your choice words.
Here is a rule of thumb that will be familiar to many who manage risk in a professional capacity:

The time to get creative is when you face a capped downside on the one hand, and an uncapped upside on the other. The time to get conservative is when you face the opposite condition.

The reason for this rule is that creative policies almost never work; but when they work, they have a much higher chance of working extraordinarily well than conservative policies do.

The UK is facing a capped upside and a huge potential downside. The UK is choosing to handle this situation with a creative experiment. This experiment will, in all likelihood, not succeed. And unfortunately most values of "not succeed", in this context, map to catastrophic outcomes.

Time, as always, will tell.
What's wrong with a link and no password?

Seems like the rooms are meant to be fairly disposable, so any situation where you would normally "change the room password", you instead just change rooms.
I'm an anaesthetics and intensive care trainee, so I know something about ventilation. The reason COVID-19 patients need to get ventilated is due to a failure of oxygenation - the infection causes direct lung injury (ARDS) which impairs oxygen absorption in the lung tissue. Normally we breathe room air, which is 21% oxygen, this drops to around 10% oxygen in the arterial blood due to inefficiencies in the absorption in the lungs. In a normal healthy patient breathing 100% Oxygen, their arterial oxygen content would be around 90%. ARDS significantly impairs oxygen uptake by the lungs, in severe cases patients breathing 100% oxygen may have arterial oxygen concentrations of just 8-10%.

The purpose of ventilation in these severe ARDS patients is to augment oxygenation of the blood, using a combination of techniques including end-expiatory positive pressure and inverse-ratio ventilation, among others, and support the fatiguing respiratory muscles. Because the lungs of COVID-19 patients are already injured by the infection, they are very prone to further ventilator-associated injury. Modern intensive care ventilators have complicated computer-controlled 'modes', which allow precise regulation of ventilatory volumes, pressures, rates, timing, and gas blending. The ARDSnet trials in the early 2000s demonstrated the importance of carefully managed 'lung protective' ventilation, poor quality ventilation is likely to cause further lung injury and make the patient worse, not better. Therefore amateur ventilators are unlikely to be beneficial in COVID-19 unless they can provide similar lung protective ventilation, which would make them quite complicated.

Additionally, ventilation is just one component of the management of sick COVID-19 patients. First you need to pass a breathing tube into their trachea, which is a challenging and risky procedure when performed by a skilled operative in a otherwise well patient, let alone someone on the brink of respiratory failure. Once intubated you will need to keep them deeply sedated, otherwise they will strain against the ventilator and make effective ventilatory care impossible. This requires equipment, drugs, and skilled staff, all of which are going to be in short supply.
UK Gov advice to "Stay at home if you have coronavirus symptoms ... testing is not needed" is another reason for the paucity of data.
https://www.nhs.uk/conditions/coronavirus-covid-19/
I think this is really a battle against ignorance. Until people see results in front of them they aren't going to respect these rules without authoritarian measures.

Best is to shut everything down for a month THEN let 40s and under back to work. By then, hospitals will have been overrun but hopefully on the upswing and people will be a lot more sober and willing to listen.

I imagine once the shutdowns happen and reality sets in, people will not want to go out and expose themselves willingly and politicians will rather keep everyone locked up as long as possible, but that is a mistake too. Everything hits with a 2 week lag so it is import to trust the trends and the analysis rather than the current situation - I expect us to be too conservative on the way out just as we have been too cavalier on the way in.
The point is to serve as a disincentive to ordinary people thinking "Oh, I can make a lot of money doing that."

It crossed my mind, when news of the coronavirus first broke, that I could make a lot of money speculating in toilet paper, canned goods, rice, and beans in the near future. (I did all my prep shopping 3 weeks ago, but didn't buy more than we personally needed as a family.) I didn't because a.) a little voice in my head said "Do you really want to be that asshole?" and b.) it occurred to me that it was very likely that powers that be (governments and market platforms like Amazon) were going to crack down very hard on scalpers, and it was not worth going to jail for. Turns out I was right about that - people are not going to jail (in the U.S. at least, I heard they may be in Europe), but they're facing $5000 fines per item or eating the cost of buying & disposing of the items because Amazon revoked their seller license.

The point of highlighting laws like this is so that people aren't tempted next time there's emergency to do the same thing.
> taking children from parents. Needless to say, that will never happen in the US

They separated Native American and immigrant families in the recent past, why stop now
51% of patients requiring intensive care in Italy are in the 50-70 range. 12% are younger than 50.
Won't you possibly get some information about some passengers by doing this, if you know / can figure out the distribution of the random numbers?

E.g., say that the random numbers are uniformly distributed between -200 and 200. If somebody says a number like 425, then I know they weigh at least 225 pounds. And the probability they weigh more than 225 - k pounds is 1 - k/400.
Thanks for posting this. It's exactly the sort of analysis I would want to do if I had way more time, and he explains his reasoning completely in a way that a non expert can understand (and provides his models), perhaps because he is not a professional epidemiologist.
But if the price floated the empty shelf situation would have been mitigated.
This is true of other some, but not all other coronaviridae so I suppose it's not a surprise but I also haven't heard any data on this.
Video by Ben Orlin of Math with Bad Drawings fame:

https://mathwithbaddrawings.com/author/mathwithbaddrawings/
These are great suggestions, thanks!

I especially like the last one, particularly for a user's first creation - because if their first creation doesn't work out so well, it's often their last. Auto-creating a few jobs based on their content image - with styles that are known to work pretty well - would really improve their experience and first impressions.
> It's still an increase in pandemic risk and needs to be understood that way.

It’s not mutual exclusive. I do get your point. But if restaurants are open and government allows them to remain open then this is a personal risk assessment as to how much public and other people handling your food you are willing to accept. That’s what I mean.
Chrome University 2019
As someone who grew up tinkering with computers I can relate but then I remember the perception of my elders towards my generation. I remember all the things I couldn’t do or didn’t pick up on that my family (and extended relatives on the homestead) could do. They could so easily fix and build everything and anything around the house and farm. Everyone was just so incredibly handy.
Because herd immunity assumes a way more behaviour and process control then you would have- even in a borg like society.

Its gerontocide, nothing more, nothing less - by incompetent/corrupt governments which will be swept away by this anyway. I greatly fear for my parents, elderly coworkers and those professors at my university.

A whole generation has grown up, incapable of proper reacting to catastrophes. What we see here, is basically appeasement to a biologic disaster, in hope of saving a ailing economy.
Some Apple employees say company's secrecy makes working from home challenging
> In a situation like this, the responsibility must be shared

Why not in other situations though? The elites avoid taxes, Boomers have houses, banks are pumping up the asset bubble, while young people have student debt, can't buy a place to live (or even a car), have no assets and, if they're lucky and productive and high-earners, they "enjoy" 20% higher tax rate than owners of capital... Why exactly should anyone now act in a way that is detrimental to themselves, to save some other predators?
Merkel said that she expect that the 40%-70% of the total population of Germany will be infected. https://www.indiatoday.in/world/story/coronavirus-angela-mer... She only has a PhD in Quantum Chemistry, and is not an Epidemiologist, but I guess she has good advisers. Anyway, as the current article says, using the SIR model the expected part of the population is higher. The exact number is not clear, but for simplicity and some optimism we can assume a 50%.

All the shared graphics use a Gaussian-like blob with a 0 at 0. I didn't fit them, but they look very gaussian-like to me. Some may be a spline or a Bezier curve or whatever the graphic program has. I agree that using a Gaussian is a weak point of the original article, I'd like to see a SRI simulation, it's just a simple differential equation.

The exact graph is an asymmetric blob with two sigmoid-like parts. Here is a nice graph https://simple.wikipedia.org/wiki/SIR_model It is not a Gaussian, but it can be somewhat approximated by a Gaussian, at least in a hand drawn graphic.

The main point of the original article is that the number of beds in hospital with the equipment to treat the bad cases is much lower than the estimated patients that need them at the peak of the infections. He estimate 170,000 ventilators and 3,000,000 patients that need a ventilator at the peak (in USA). It's almost a 17x, not a 2x or 3x like in the graphics in the news.

To flatten the curve, if we decrease the height it will increase the width to conserve the area. (The shape will change, but not too much. In an exact simulation you will see the difference, but not in a graphic with a blob.) So the width must be increased x17. So if we estimate that at the current infection rate the pandemic will last 1 year, the flattened version will last 17 years.

The exact number depends on the shape, so using a gaussian instead of the real model will change it. The exact end point is arbitrary, because with both graphic it will fade slowly. Let's say between 15 and 20 years.

The exact numbers of peak patients and beds in hospitals are controversial. I think he is using that the 20% of the patients need hospitalization, but I hope the real number is much smaller because many mild cases are not tested. Let's be optimistic and say 5%? That reduce the flattened epidemy to somewhat like 4 years.

Most people assume that it's enough to get toilette paper and hand sanitizer for a month, and after a month or two the flattened epidemy will be over. It will be longer. I hope that we can get a vaccine in a year to kill most of the tail of the curve, and even the peak if it is flattened enough. The author of the original article is less optimistic and ask for more containment measures.
The Hardest Part of Telecommuting
Maybe, I barely remember the 80s, so you might have a point. But even so, the cool business people tended to be the rich CEOs and Wall Street types (and I remember plenty of those as villains as well, think OCP from RoboCop) but still, they weren't the ones using the computers.
I went to Costco and saw people buying up to the limit on random stuff, and they end up with 6 months of toilet paper, 1 year worth of pasta, etc. I wanted one box of diapers (one lasts over a month), and there were only 4-5 boxes left when there's normally 20+, even when there's a good sale. I have never seen them be out of baby wipes, but they were out when I went (which is a shame because we just ran out). In fact, they had to shut down a local Costco because people are fighting over toilet paper.

COVID-19 isn't going to be some world ending thing, it's just going to put some supply pressure in the short term until production and distribution can ramp back up, but people are treating it like it will be. It's really frustrating.
It’s not just encryption - although that might be the main first target. It’s any conditions all that the government might arbitrarily decide to impose as “best practices“.

I think anyone who’s worked in IT long enough knows that ‘following best practices’ is a euphemism for ‘do it my way or else’.
Show HN: Tofu – Meal planning kept simple
Again, if you don't come into contact with the vulnerable (or anyone else who does) then you aren't putting anyone at risk and you are developing herd immunity which will in time likely end the virus.
The video above (at least one of them) was showing an entire automation line built on Roche technology-- easily an order of magnitude more than 400k. The Cobas 8800 is just a component of that entire line.
Insane, but we already knew it thanks to their past decisions. This is just the last confirmation. In the best case we’ll have close to 1M deaths if they succeed with their strategy.
The B2 especially is huge (there's one on display in Dayton) and likely slow. If it's been localized to within a few km or so, it's probably a sitting duck to any reasonably modern air force.
Neat! See also: https://fklearn.readthedocs.io/en/latest/, which wraps sklearn in a much-improved functional API.
The issue with that approach though is how do you effectively prevent reinfection of the region when all counter measures are suspended? Another carrier could reinfect the region again and all that previous work came to nothing.
The name came from a Roche-owned lab subsidiary that later merged with another big company from California - Roche retained a 49.9% stake in the new company.

Roche sold their stake in 2002.
You have a .2% mortality chance once you exhibit symptoms, right? That's much greater than no risk.
I think the development of a vaccine in a few months is unlikely. I think however the identification of somewhat effective antivirals in a few months is probable. There are already two antiviral candidates in trials, which are simpler to run than vaccine trials: remdesivir and lopinavir+ritonavir. Also, "transmitted immunity" is being (re)developed:

https://www.nbcnews.com/health/health-care/doctors-push-trea...

Antivirals won't stop the outbreak but they could save thousands of lives.
You're right. I swear I saw some article that said that South Korean drive through would text results as fast as 15 minutes, but looking at a couple more reports just now all said 24 hours.
Whether someone is a “digital native” or not has everything to do with whether they’re 1) interested in creating something, and 2) what they’re interested in creating.

I may think they’re really missing out on everything that a computer/the internet can do, but there are plenty of people really into cars that feel the same way about me driving a 23 year old vehicle.
Wuhan had the great majority of cases in the entire world. The other provinces of China are more analogous to individual European countries. They locked down for a few weeks and have already come back up.

The long term strategies for Korea and China are the same: carefully identify new cases as they come in from outside, find their contacts, and isolate them as soon as possible. Temporarily lock down small regions on an individual basis if necessary. They've already been doing that with some new cases coming in from Italy.
I fear that when the PM said that his decisions are driven by science, he means economists, not virologists.
The Hologic Panther Fusion is another automated open platform.

The decision to lock people is for FDA approval. FDA approval means more labs can run your test and reimbursement is more of a sure thing.
We are about 2 weeks behind Italy in death rate, which is the only measure that can be reliably compared between countries, due to differences in test rates and criteria to be tested.

Is 2 weeks "grace period" before implementing a lockdown and starting the heavy measures worth it in the long run? I don't think so.
Shadow Cities (1997)
This. A 1000 times.

Nobody really wants to focus too much on build configurations when working on things, they should 'just work'.

And CMake, although I am using for a long time already, is not the offering this 'just works' experience I am afraid. It is so easy to introduce side-effects, and figuring out the intended way to include a project can be a big pain when documentation is sparse. Sometimes I wished I had a CMake debugger. And with modern CMake I feel like this got worse to some degree.
Got the Politit honour for all the scientific work. It's yet another accolade for their recognized expertise.
That 0.2% is in line with the flu, and also, generally is attributable to those with comorbid conditions, especially ones that compromised immunity. If you're young and healthy, it's not 0.2% -- it's much lower. If you're young and unhealthy it's not 0.2% -- it's much higher.

There's no such thing as no risk. I'm putting myself at risk of all sorts of things by leaving the house.
If you've got an amazon echo or equivalent, try this experiment: disconnect your internet. Now issue a voice command to it. Why is your light not switching on? Why is alexa not answering your questions?

Now you know why I want "off-site cloud" for particular things. Not everything. Just what matters. A few things here and there.

There's nothing wrong with the cloud and nothing stops me from using its benefits. Except one minor detail. My use-cases are likely different from others. I wish to keep cloud access as needed but also just a little bit more.
Aside from the fact that you may spend a week or more spreading virus all over the place and to potentially dozens or hundreds of other people with this approach, there is at least a 1 in 10 chance that, if infected, you will need hospitalization and serious care. You will contribute to overloading a medical system, without which even your mortality rate would be closer to 5% than the <0.1% you seem to assume. It is simply not the case that this has no effect on the non-elderly; severe pneumonia is a debilitating condition even for the young and fit. For a large fraction of everyone who gets it, this is WAY harsher than any flu you have experienced, and even many in your demographic will need extended hospitalization.
Coronavirus Live Updates: France Closes Companies and Spain Towards Locking Down
Roche ramped up production in anticipation of approval, so hopefully they can.
Corona Simulator
I would love to know the legal implications of running a service where people are able to stream copyrighted content to others, or to share subscription services like Netflix in violation of its TOS.
> In all other outbreaks (even the US one) there has been widespread testing

Can you back up that claim? From what I've read, the opposite seemed to be the case, especially in the USA.
It's mostly a commercial decision. Reagents have very high margins and recurring revenue is more attractive than large one-time purchases. Illumina does this with genetic sequencing as well.

edit: There are some informal standards like 96- and 384- well plates that make it possible to have third-party consumables with some machines, but there is no incentive for a for-profit company to design open platform.
The commercially available BioFire panel tests for regular coronavirus, NOT SARS-CoV-2 (the virus responsible for Covid-19). They may have something in the works. that said, these machines are not very high throughput; more of a point of care test for small/medium hospitals.
Our Crystal Ball is not Clear
Many are only ovo-vegtarian.
I don't know of anywhere that provides a comprehensive list of things COVID-19 isn't. Could you provide a source that suggests that there is one?

Everything I've seen so far (eg, [0]) points to the virus itself damaging respiratory tissue, and normal body immune response aggravating that locally to some extent.

A cytokine storm [1] is, as I understand it, a massive systemic immune overreaction causing way too much inflammation, overwhelming the body all at once.

That Wikipedia entry suggests that SARS may have caused a cytokine storm, at least in some patients, but from it and everything I understand about the phenomenon, it's recognizable in epidemiology largely by the greatly increased incidence of deaths among young, healthy patients—which is not at all what we see in COVID-19.

[0] https://www.uticaod.com/zz/news/20200313/what-does-coronavir...

[1] https://en.wikipedia.org/wiki/Cytokine_release_syndrome
Our setup is quite similar to this. Some differences - each environment is represented as a helm parent chart with each application being a child chart. Each environment chart has it's own repo where values.yaml supplies environment specific overrides for each application. Each application has its own repo where the helm charts and application source both reside.
paper - https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v...