skysight-inc/HackerNews huggingface dataset:
heres some reading to get started.

you dont need the electrophoresis unless you want to do something like restriction analysis across the different samples.

mainly its a test for presence of sars-cov2.

very often this involves annealing a molecular reporter such as a dye florescence probe, to the mRNA with specificity to regions characteristic of the strain your looking for.

https://www.researchgate.net/profile/Idania_Gonzalez-Perez/p...

https://www.fda.gov/media/134922/download

---------------------------------------------

https://hackaday.com/?s=PCR

https://hackaday.com/2016/05/03/dna-extraction-with-a-3d-pri...

https://hackaday.com/2013/09/23/openfuge-an-open-source-cent...

https://hackaday.com/2013/09/21/vcr-centrifuge/

https://hackaday.com/2020/03/10/open-source-collaboration-ta...

-------------------------------------------

https://news.ycombinator.com/item?id=22552391
You don't even need a type system to eliminate memory unsafety. Show me the memory unsafety in lambda calculus. (and don't forget that, as you said, we're talking about languages, not runtimes)
> In Catalonia no one can enter or exit.

This is only for four cities of Barcelona, not the entire area. Like the 1% of the population. Is an unprecedented measure in any case. Lots of social experiments this days.
Knowing twilio's business model, I knew exactly what was meant by the title.
Taking the exponential growth into account, we're somewhere around 11 days behind Italy. Unless something drastic changes in the next few days, whatever Italy is going through now, is what we will be going through in only 11 days.

See the chart in this article for details on the 11 day difference.
https://www.econlib.org/the-answer-one-week/
I’m going to get needlessly harsh here.

Is this a for-profit company?

Do you think for-profit companies should be able to advertise medical products? Because in my view they shouldn’t, full stop.

So you’re up here telling us that one of your challenges is that you can’t advertise anywhere, and to that I say “good.”

Perhaps you and your 81% white male team/advisors (with zero female/minority people with executive level decision making ability) could answer to some of that.

My condolences to your girlfriend, but this isn’t an issue that a web CRUD platform is going to solve and seeing it laid out in typical Silicon Valley marketing copy is kind of sickening. It reminds me of some of those less than stellar web therapy platforms that seem like another way to Uber-ize the professional therapy workforce into poverty.
N8n raises seed after success on Hacker News
Where do the numbers come from?

You hardly can compare the number of tickets in an issue tracker of an open source software (let it alone being a distribution, collecting thousands of packages and reporting straight to upstream developers) with the information spread about closed software.
>> We would love your help figuring out how to get past this bottleneck.

Can you restructure the strategy so that the business can operate with a low (initial) growth rate ?
You might find success by partnering with regional public health officials, who would sponsor or subsidize real world advertisement.

I live in Europe and last time I was in NY the subway was full of public health billboards encouraging people to carry naxalone.

Maybe you can convince one official or non profit somewhere to subsidize those billboards for you.
You're not only solving a personal problem for the addicted, your solving a societal problem. I imagine that if you can show efficacy in one or two pilot regions, you'll have an easy time partnering with other ones / raising money (maybe non vc) / funding acquisition yourself.

My $0.02, hope it helps and good luck, nice to see startups doing important things.
Bill Gates has stepped down from Microsoft's board
Or game developers can just hire non-union employees. The reality is that game development studios can get away with poor work life balance because there's people who are passionate about making games and are willing to accept poor working conditions to get a chance at their dream job. This Stage Actor's Guild exists, but aspiring actors still have to work second jobs to put a roof over their heads. When a job is a lot of people's dream job, conditions are going to be poor because the supply of potential labor is very large as compared to the demand.

Also, I have no idea where you get the idea that unions can somehow force collective ownership. The company belongs to the shareholders, unions don't magically get to take other people's property.
So that's what I feel on massive sound stages that are dark after we are done shooting for the day.
> Not necessarily "hot" swappable

"Hot swappable" usually means you can swap it while the machine is turned on. At least, that's how people use the term when talking about harddrives.
What happened with it? Why didn't you continue with the concept?
Like most things on the internet, Reddit has a great community for this haha. But yeah, it's been really cool to see how professional and business-like the industry has come in the past few years.

It's fairly expected for a serious operation to provide analytical data on alkaloid content and/or employ dedicated quality control personnel these days.
> If we want security standards, they need to be legislated democratically and applied to all devices -- not left up to consumer choice.

But if you want security standards, and bob does not, why should bob be forced to want them?
I don't see why that's dangerous. it's just a rephrasing of "this assumes x holds true" and if it doesn't none of this matters.
I'm very much not a supporter of the current government, but I have to say that I'm impressed by their measured response. It's infectious, we are all going to get it (even those that hide) so let's get on with life, try to slow the spread to keep pressure off the NHS at the peak for sure, but enough already with the flapping. Seems to be a fairly common view in London at least, still hard to get a seat in the pubs on a Saturday night.
Predicting the Effects of the Covid Pandemic on US Health System Capacity
And then there are the people who want to be paid whichever is the higher of the two approaches.
I’m not sure why you’re getting downvoted, what you’re posting is accurate. I had a former employee who worked as a software developer at a company that had union electricians. One day he got a new monitor, but it had to sit idle on his desk until an electrician could come and plug it into the wall.

He had to occasionally adjust controls that were slotted (potentiometers). He had a little screwdriver that he kept in his pocket to make that easier. The electricians filed a grievance with the union because he was carrying electrician’s tools.

I think there is some good in unions. I think there is also some bad.
Microsoft says Bill Gates stepping down from company's board
Funny, I feel the same way about MBA mills and slash and burn private equity firms.
Show HN: fdir – The fastest file system crawler for Node.js. 10k files in 13ms
And the real lesson here is HTTP probably isn't a good protocol between your proxies and your backends, and you should probably use HTTP/3 to fully eliminate this entire class of bug.
* At StubHub, the company I founded, we picked off the “tickets” category.*

[...]

3. Develop a strategy to defend against disintermediation [...]

4. Consider building a data moat

It's worth reading this because it's unusually frank about the deliberate exploitation customers and suppliers and essentially advocates MITM economic attacks by splitting trusted suppliers and consumers from each other and establishing and maintaining convenience, economic, and information asymmetries in order to milk the market for profit.

We need more things like craigslist and less, much much less, of this sort of thing. Verticalization can create value, but as described here it is far more about extracting it, by commoditizing and centralizing what were previously distributed peer-to-peer relationships. The argument is that these verticals are more economically efficient, but this is only true in the sense of maximizing the dollar value of each transaction (and taking a commission); this comes with significant negative externalities for the participants - loss of privacy, loss of transparency, loss of negotiating ability, loss of autonomy, and loss of opportunity.

They're not creating a marketplace, but a company store in which the management has been automated away. Because it's distributed, striking is impossible and the only way workers in the system have any relief is to organize off-platform and then attempt legal action, via a court system which the corporation can stack directly (through hiring very high priced legal representation) and indirectly (through lobbying and campaign contributions).

Craigslist created a marketplace and charged a small fee for very high-value transactions selling vehicles or hiring for employment. This is just a land grab.
I linked this above http://news.southcn.com/nfplus/gdjktt/content/2020-03/09/con...

It seems to me beyond reasonable doubt that quinine derivatives are useful in humans. A miracle cure maybe not but almost certainly useful.
If they took the 2% least savory bus riders and kicked them off, even calling them an Uber Black, I think they’d triple their ridership.
A very thorough analysis. I'd assume that the newer generation, the ecologically-conscious one, will be taking public transportation more, for sure. And even though many of these people also fall into the category of those 'working from home', they're also the more outgoing ones. So there's not really a reason to say buses will keep suffering, it's likely to be a cyclical thing.
If nine woman can produce a baby in one month, can 1700 women produce a baby in 3.8 minutes?
Can someone recommend some good Discord channels to hang out with on diff intellectual subjects?
That works as far as it goes. The problem that we're starting to see is empty shelves. While at the store recently, I saw one of the store shoppers looking at an empty shelf muttering "I don't even know what to substitute here..."
7 Ways I'm Finding Joy During Covid-19
Everyone and their mother is profiteering, errr, I mean discounting their services to help people affected by COVID-19.
I read and re-read this "examples" docs page several times:

https://github.com/jitsi/lib-jitsi-meet/blob/master/doc/API....

Hats off to anyone who can rapidly go from those docs to a deployed and working app. I was able to modify the repo linked in the parent to suit my needs in roughly 2-3 hours, much of which was install/setup.
Exactly. It's going to be a list of check-boxes that the manufacturer will do the bare minimum to meet. Or they twist their process and wording to make it look like they are meeting the requirement.
Tor team warns of Tor Browser bug that runs JavaScript on sites it shouldn't
What's wrong with charging more for people who use more?
Microsoft announces change to its board of directors
Bill Gates leaves Microsoft board
Political campaigns and your personal data
Second that. And yet, the B2C asymmetry was and is there regardless of whether one is "forced" to relinquish control over part of their machine. The current attestation models are an extension of the power imbalance. Intel, being a profit driven company, sought to meet its customers' demands.
You can generate similar images to print for free with Shirase: https://dokomaps.com/shirase ;)(I'm the maker)
> is not desirable for most photography applications

Hardly. It's namely portraiture that benefits from thin DoF, or similar applications where figure/ground relationship can be improved by keeping OOF elements blurry.

There are a great variety of situations where you do want as much in focus as possible. Landscape and macro photography are the most notable examples, where most high-level images utilize focus-stacking composites to simulate extreme DoF.

Certainly focus depth is a creative tool, but don't confuse expensive wide-aperture lenses for what is necessarily good.
pritnf is an awesome typo! When you're make it your compiler can catch it. "n" spelled instead of "m" is worse
Bill Gates steps down from Microsoft board
I would have to assume that number is exaggerated...
Also surprised because I thought it was a very small company (less than 50). I'm wondering if it's really useful to unionize for such a small company?
We're back to upside and downside risk. If you want "flexibility", you have to offer more. The US west coast startup culture has done OK at giving staff a share of the potential upside. The games industry, on the other hand, is notorious for even successful games resulting in studio closures, and employees exposing themselves to the risks of crunch time being rewarded with layoffs.

I know the ideal libertarian corporate structure has a single CEO making a huge salary controlling a vast collection of precariat workers who are paid the bare minimum to avoid them becoming homeless, or slightly less, but this is .. unpopular with everyone else.
Data Pass doesn't work?

www.t-mobile.com/support/plans-features/data-passes
I don't think we're talking about the same thing.
Thanks. Sure!

Just thinking of some modern writing inline with what the previous poster mentioned, such as:

http://sirisofcalifornia.com/168833-books-jackie-pullinger.h... (epub/pdf/txt)

Note that I've met that person, and been to those places. They take heroin addicts and convicts -- about 20 to 30 in one building; they live 24-7 together, without previously knowing each other, for 3 months -- and come off heroin or other drugs in that time. What was cool was getting to see that, and see how peacefully they live together, even given their background

Addendum: Loads more, sorry I haven't met these authors tho

https://www.goodreads.com/book/show/1022866.Run_Baby_Run

https://www.youtube.com/watch?v=VDKLYFYc40Q (I like this guy)
Enlightened self-interest is enlightened nonetheless.
If you're looking for a reputable service of "someone to help you work" I highly recommend https://www.focusmate.com/

It's not about meeting new people, in fact, socializing is discouraged, but it is about real people helping each other by just being there.
Isn’t that the same argument that can be applied to health? Vaccines, clean water, fluoride etc promote your well-being, and protect you from various bacteria and viruses.
Why shouldn’t you protect your “digital” self as well?
The internet, by it's core design, allows anyone to send as much data as they like with any content and pretending to be anyone.

I don't think mandatory security requirements for webcams is going to do much about that...

Instead, we should be thinking about how packets can be source and destination signed, and how unsigned packets can be dropped in the network rather than clogging up their destination.
For restaurants, figuring out how to safely turn in person restaurants into sanitary delivery only restaurants could be a life saver.
Jack Ma to donate 500k test kits and 1M masks to the U.S.
The phone system switched call routing from in-band signalling (that is, tones you could hear on the wire) to out-of-band signalling (where control information went over separate channels to content).

Another approach is reliable encapsulation. Ethernet and TCP/IP, for example, are technically all in one channel. But packet content won't be mistaken for protocol information. You could also look at things like SSH and how it has multiple channels: https://tools.ietf.org/html/rfc4254

I'm sure there are other approaches, too, and I hope people will mention them.
maybe because people have found out his foundation patented the corona virus so he is preparing to run away :D
There are prima facie limitations to this, otherwise lobotomy victims would have naturally recovered.
Isn’t this the healthcare argument but for security? Because it becomes an international problem when millions of EOL’d devices have a wormable flaw and can send enormous DDoS traffic stressing networks and taking sites offline?
Thank you for the feedback. I'm with Mender.io and we will be addressing this.
> Which version of language? Which interpreter?
Ah, very good question. Currently, it's just whatever version is in /usr/bin/$LANGUAGE. You can see in /home/$USER/.dit-languages how the language configurations are defined. You can add another configuration, just by copying the Python configuration, changing the name and path to Python2.7, and then doing this:

validator Python2.7 {{ //Older python code }}

In the long run, this should be made a lot simpler I think, which leads me to your next question:

> How do you make sure that both sides of communication run the same logic?
This will probably require some way to send language configurations along with a dit. If you send someone a dit which requires Java code, but the client doesn't even have Java, the dit should be able to recover from this somehow, by automatically installing Java, creating the configuration, etc. I'm not exactly sure how this should work, but its one of those clearly solvable problems that I'm trying to leave be until I have a good example of the real problem.

> Is the code transmitted together with data? What is benefit of running this code on receiving side instead of sending side?
Yes, the code is always tied directly to the data. Currently, source code must be sent, but in the future, it could pull from a link, or even run the validation offsite, via an API (important in case you want closed source classes).

In theory, there is no reason for the receiver to run the validation, (assuming the receiver trusts the sender to validate). But one purpose of dit is to prevent a message from ever being separated from it's meaning. If a client receives some data in a dit format they have never seen, they can learn how it works by looking at the dit. The validation code can even be used as ad-hoc unit tests when trying to process the data automatically. And also remember that querying (and converting, mutating, anything else that might be added) also requires the dit code.

> Do you serialize and store validation and query code on disk? Is this good idea?
Currently, the modified code is regenerated every single time. You can see the code in /tmp/dit/. This is slower, but it does mean that the code and serialized data are always as new as possible. Caching could be an option, if done carefully.

> .old data that cannot be queried as well as new data. ...old dates cannot be converted to various date formats while newer can.
I'm actually not sure what you mean here, I can't picture how this could happen. Could you explain?
"4. There's evidence that there are multiple strains, can you get both strains?

You shouldn't think about them as multiple strains, as of now it is 1 disease."

There have already been 2 confirmed strains, so I don't know where you're getting your info from.
Are you implying that public prosecutors have the option to not interact with criminal defense attorneys, because companies certainly have the option to hire employees that do not work for unions.
If you like this sort of technology check out the Hiller Aviation Museum in San Carlos, California. Stanley Hiller's company did a lot of early work for the US Department of Defense including helicoptors.

The aircraft on display are amazing. The mid-20th century had some incredible aircraft designers.

https://www.hiller.org/
There is a now-defunct Soviet-equivalent to HAARP called Sura Ionospheric Heating Facility, as well as facilities in Ukraine that contain similar arrays of antennae:

https://en.wikipedia.org/wiki/Sura_Ionospheric_Heating_Facil...

http://www.darkroastedblend.com/2007/10/abandoned-ionospheri...

https://www.youtube.com/watch?v=rpN3KXLgCz0 (location not disclosed, but this Youtuber makes several videos of abandoned sites around Ukraine)
Hangouts/Meet hardly works for me at all, and definitely not in Firefox. It's like the old days when "DOS isn't done til Lotus doesn't run".

It's too bad, too, Hangouts used to be a nice platform.
Bill Gates to step down from Microsoft, Berkshire Hathaway boards
It should be noted that this happens to you to some decree any time you get pneumonia.
Or in 2020: must keep the stock market up.
Let me write the source code for the label printer...

def IsDeviceSecureEnoughForUKGovernment():
if manufacturer=='Huawei':
return "Not Secure. Use sparingly"
return "Certified Secure"
I pretty much agree with you and second guessed including it.

My only justification for including it is that personal projects teach you about how technologies work at the 0-to-1 step (and maybe 1-10). I knew smart people who were extremely confident in the superiority of tool/framework X, because they could write unreadable boilerplate in it for all of their personal projects. Everything was a nail for the hammer.

I generally agree that it’s good practice to start with an empty dir and build from there. But IMO it is no substitute for working on or around projects that have been in prod for at least a couple years.

I agree that working on your own projects is a great way to develop instincts that lead you to being high impact, but it probably took me a year of working experience context (2 or 3 internships) before my side projects actually began training that muscle. I can easily imagine mileage varying there, however.
It will be a cascade. Rents is often backing a mortgage, so mortgages need to be suspended, mortgages backed by bonds and deposits, so interest repayments in people's retirement accounts need to be suspended and so on.
Show HN: AI powered app for visually impaired on Google Glass Edition 2
How is the "right to repair" different from "I want access to the design documents, source code and the entire supply chain for spare parts"? Where do we draw the line?
How sperm unpack dad's genome so it can merge with mom's
Wait, second life is still a thing?!
Girl gives an AMAZING Acoustic Cover of Elastic Heart by Sia
5% needing ITU was initial estimate. In Italy it’s 10% due to an elderly population. And some on ITU would survive without ITU but it does improve chances. You make good points, I’m mostly just saying there is a high degree of uncertainty
Also stepped down from the Berkshire board as well.

Given that he stepped away from a day to day role in 2008 and then stepped down as the chairman in 2014, I'm guessing he's focusing on his foundation.

He's still the 8th largest shareholder according to Bloomberg's records(103,000,000 share), which is pretty impressive given that the 7 entities above him are all funds.

Incase you wanted to know who the remaining 12 board members are:

With Gates’ departure, the Board will consist of 12 members, including John W. Thompson, Microsoft independent chair; Reid Hoffman, partner at Greylock Partners; Hugh Johnston, vice chairman and chief financial officer of PepsiCo; Teri L. List-Stoll, executive vice president and chief financial officer of Gap, Inc.; Satya Nadella, chief executive officer of Microsoft; Sandra E. Peterson, operating partner, Clayton, Dubilier & Rice; Penny Pritzker, founder and chairman, PSP Partners; Charles W. Scharf, chief executive officer and president of Wells Fargo & Co.; Arne Sorenson, president and CEO, Marriott International Inc.; John W. Stanton, chairman of Trilogy Equity Partners; Emma Walmsley, CEO of GlaxoSmithKline plc (GSK); and Padmasree Warrior, founder, CEO and president, Fable Group Inc.
Recently I wanted to get on the roof of our building, but the new mgmt co had put a four digit combo lock on it. I eventually decided to brute force it and resigned myself to about a half hour of drudgery. Wanna guess what the combo was? My lucky day: 0000! Got it on the first try. (tears of joy emoji)^3
Ask HN: Which Java templating engine for web are you using?
Thymeleaf, JSP, FreeMaker, Handlebars... any other? How satisfied are you with your choice? Would you use it on new project?