skysight-inc/HackerNews huggingface dataset:
The problem is not vaccine development - the bottleneck is TESTING.

The vaccine itself can be developed in literally DAYS (for most viruses). The problem is that it takes a YEAR to test it comfortably in humans. For something that you'll be delivering to otherwise healthy humans, the bar for safety is extremely high.

...now the modern counter-argument is that if 4% of people are going to die globally, then maybe the safety bar should not be so high (this time).
Quick ideas/links to use when you're trying to WFH with your kids
‘Cure’ found for coronavirus in Australia
> the exception being for companies that is going to go bankrupt

This is not a small issue. If businesses are closed for two or three months, I believe half of the businesses in this country will be close to bankruptcy.
Almost every library out there is on Maven Central. Even Oracle JDBC drivers are now (finally) on Maven Central.

If MC goes away as it exists today, the Java Ecosystem will take a huge hit as almost every open source project would stop building in CICD environments from the get-go.
Could the economic gains from fewer retirees consuming lots of medical care and social security funds outweigh the losses in senior experience and volunteerism? Maybe. But not to them.
I mean the idea that breaking a window is good for the economy because the glazier gets paid.

https://en.wikipedia.org/wiki/Parable_of_the_broken_window

No relation to the other. Sorry - my mistake in assuming sufficient familiarity with both to disambiguate from context.
I absolutely agree. I got a broken 650 from my sister, fixed it with a cheap easily available part, and it has worked beautifully for the last three years.

It is also a joy to maintain and was obviously designed by people who care about maintenance being reasonable.
I guess that would catch the casual scofflaw who hadn't thought things through, but it's not like it's terribly difficult to just lookup a couple stores in the vicinity of where you actually want to go. combine that with the fact that you're apparently allowed to visit friends/family who "need assistance" as well as walk around for exercise, a halfway clever individual could have an excuse to go pretty much wherever they want. of course, there aren't many places other than the grocery store that are actually open.

also, how does the conversation begin in the first place? do they pull you over under suspicion that you're not on your way to a grocery store, gas station, or friend/relative's house?
I saw one really good comment - we'll know for sure if we under reacted, but we'll never know if we overreacted
Because different versions of the struct have different sizes. That’s a C artifact.
Regardless of Bitcoin pros and cons this event will increase centralization and by a lot. Whales will acquire cheap hardware of bankrupt smaller or more reckless competitors and after stabilization there will be fewer major players, with remaining ones being much bigger. I wouldn't even discount emerging of "benevolent 51%" entity which will be a monopolist "for the greater good".
You are assuming that COVID will go away and not become a yearly thing. Also assuming that this type of shutdown won’t become the new normal in response to a virus. ( something that happens every 4 or 5 years )

I too am hopeful, but I think there is 10-15% chance of massive long term economic downside
What if you need to see your family, or help out a friend? Or vice versa? Or go pick up medication? This comment strikes me as pretty insensitive.

I live in SF and don't own a car. It's never been more tempting for me to get one. I live alone, far from family, and now seemingly can't see my friends or significant other. It's already getting incredibly lonely. A car would enable me to at least go straight to my gf's place without being in contact with anyone, or to the pharmacy for meds without taking public transit.
A lot of ventures that were hanging on by threads will be ruined by this, so the pandemic is likely to clear out a lot of the weaker businesses as any good recession or crash is apt to. It will take a while for the marker to grow around that loss (though good in the long term, there is pain in the short). It could also trigger a housing correction, which has ripple effects on the construction industry, and those people are no longer eating at restaurants, and so on. Think of busts being inevitable anyways, and a crisis is merely the way into one.
> We've had 71 deaths from COVID-19 so far

It seems unadvisable to look at exponential curves with a linear mindset…

Consider a different way of estimating:

There are >300m people in the US.

It's easily conceivable that >50% of them could catch the virus.

CFR is likely to end up >.5% (Korea, with excellent medical care and very widespread screening, so probably one of the smaller numerators / largest denominators around, still currently has rates higher than that).

That would already give a rather high number of fatalities. And if the health care system gets overloaded, CFR is going to be quite a bit higher than assumed above.

[Disclaimer: Not medically trained or otherwise qualified]
It might not take that long. If the vaccine candidate is viable, Stage 1 trials could be completed in a few months since there's already tons of patients with COVID-19 going to hospitals where they can be monitored for a maximum safe dose trial. The FDA might be able to waive most of Phase 1 similar to some oncology drugs and once it hits Phase 2, they just needs enough data about efficacy and safety to declare it a breakthrough therapy. The reality is that many clinical trials take time because of how long it takes to set up the infrastructure, get patients, and coordinate with an understaffed and underfunded FDA. If the entire agency is ordered to focus on COVID-19, I think it could happen a lot faster.

That's only if the vaccine works though. If do that process and it turns out it doesn't, it could make the situation a whole lot worse.
Flowsheets v2 Demo
>4. Do we seriously trust the US Government to not mess this up? California is the [0]world's fifth-largest economy and still spends more than it takes in

That's because the citizens of California send most of their income taxes to the Federal government, where a portion of it is sent to red states to subsidize them. If California somehow seceded tomorrow and that money was sent to Sacramento instead, the state would suddenly have a budget surplus.
I don’t get this. If a meteor hits the earth and wipes out 25% of the population, that would be external. But there’s absolutely no reason to believe the significant reduction in economic activity and wealth would be temporary.
Things to Improve Your Website Accessibility (Checklist)
> The government has a right to that information. For-profit companies do not.

That seems like a very arbitrary distinction, and I'm not sure how one arrives there. There are a lot of for-profit companies that build business around data analysis of things that most people could count (given time and inclination to do so) but do not, be it cars on the road or the average price of gasoline state-by-state. Is that a moral red-flag?
I never short stock directly, but I do buy puts.
Sulfuric acid will remove the oxide without damaging the copper. Tested and known to work: a syrupy-thick 18 molar concentration.

So that's a cyanide-free answer to the problem. Cover the ceiling and walls with copper foil, and regularly mop them down with 18 molar sulfuric acid to keep them pretty. Rinse carefully, especially the ceiling.

The cleaning solution is also a great disinfectant all by itself.
> They're still the by far largest and most successful ASIC manufacturer.

That doesn't disprove the comment I was refuting, we're not talking about ASIC production we're talking about hashrate on a given network. That just shows how young this Industry really is.
Or if your asset gets delisted. Or if there is no list.
Flexible CI/CD with Kubernetes, Helm, Traefik and Jenkins
I don't think you'll see any appreciable difference in conversion quality by switching audio interfaces at this level, particularly with the style of music you are making (which is great by the way, well done!). It all comes down to workflow, and it seems you're getting it done just fine with the Yamaha. I'd look to upgrade if you find yourself needing more inputs.

The more obvious upgrade would be a new microphone to replace the Kenwood you are currently using. An SM-58 will last you a lifetime or if you have a bit more to spend something like an SM7b will be a great investment particularly recording in untreated spaces.

Also, you could try recording the midi information of your electric drum kit and then loosely quantising/editing the takes to retain the feel. You can map these to Logics in-built drums which are pretty great.

Congrats on finishing a body of work, most don't get that far!
What's wrong with Microsoft's dev strategy? .NET continues to be the most powerful and productive platform that I've used.

.NET Core was a great move and it's all coming together nicely now, and even creating innovations like Blazor.
If one assumes that the market was a powder keg waiting for a spark to explode, it doesn’t matter when the virus part of the equation clears up
According to a news article from yesterday, Amazon Fresh and Whole Foods delivery have been stopped.
We are aiming for ‘maximum control’ of coronavirus, PM tells the Dutch
Right. This is a "hold the line" situation. Unfortunately, not one aspect of American society suggests that we're going to have each other's backs as a break becomes more and more possible. Therefore, it may be better to assume that it's every man for himself, and grab what you can while the getting's good.

This is why you have a robust social safety net. Not because the liberals and hippies think lazy people are entitled to free stuff; because everything - everything - is built on faith that the bottom won't ruin "you," specifically.
This is particularly acute since the American economy derives a big part of its drive from consumer spending, unlike other economies that may be more producer or infrastructure driven.
The current S&P P/E ratio is still higher than it was at any other time except the 1920s bubble, the .com boom, and the top of the 1960s bull market.

https://www.multpl.com/shiller-pe

There are problems comparing the P/E over time periods this long, but it is a cautionary datapoint.
There is a very large amount of corp debt on shaky ground. A lot of people are _very_ concerned that this debt is going to blow up in a very similar way to MBS in 2008.
Maybe in a year or two. In a month or so, covid will still be ramping up in various parts of the world.
There are so many assumptions in here that are IMO wrong. We're not asking for a recession. And I have no idea what you mean by "externally" driven. Everything is connected in the economy.
> Now is not a good time to sell your stock holdings (at least not anymore). This smells of a panic right now.

I'd love to make large buys of stocks at a time like this, but I have no idea whether my job/company/industry is safe. Last time I was laid off from work was particularly rough for me, and I'm only just now getting back on my feet.

The uncertainty of the situation is probably making many others think twice before buying/spending so that's going to make it harder for stock prices to recover in the short term.
If economic impacts to less-well-off people continue, though, we're going to see significant impacts on consumer spending. If economic impacts wipe out every small business without enough cash to stay afloat for 2 stressed months, we're going to see significant consumer spending, employment, and consumption impacts. Fine, everything will rebound in eight weeks... except for my local taco place, ramen place, pizza place, sporting goods place, and bookstores, which can't pay their rent for two months given a huge reduction in business.
Why the banana though?
Not OP but I don't think we'll bounce back as quickly due to the lack of urgency coming from the Federal government. I suspect we'll fall into a vicious cycle of business layoffs, corresponding dip in consumer spending, reduction in r&d/business investment as we are now and after cases taper off which now seems even further away than what it could've been had the CDC/FDA/WH been on top of this earlier. Some countries took the threat seriously and immediately took care of things.
Having worked in that 'biz' I would say this is true but a feature, not bug.

Any complex system like that is certified to operate within parameters given a specific set of equipment, software revisions and the like. Figuring out the implications of OS upgrades (much less vendor-supplied software or hardware -- even non-electronic parts) is difficult enough as it is. This applies not only to patient-facing imaging equipment but various lab equipment as well.

Such equipment should not be connected to a network of course, but that is not implied as a problem in this blog post.
PS2 memory cards but how much will they cost? And will the games depend on them? It seems like a fragmentation issues to me - even if they are fast.
I can build a wooden make shift outhouse with a dug waste hole in a few hours. In the interim I can use a 5 gal bucket with a makeshift seat. To clean out the bucket either use a bag or flush out waste with water into a hole dug at least 2ft deep then sanitize the bucket with a strong bleach solution. But I live in a rural area. This solution probably won't be as effective in Brooklyn.
Working remotely with kids at home: A few tips
To be honest i always found the idea to defend ones home in america ridiculous. They are built from wood. Most of them. One molotow cocktail or burning arrow and bow from looters, and you are literaly toast - AR15 or not.

The only thing keeping you alive and well is the social fabrique. If its torn, now would be a good point to start mending it.

Im way more worried, what will happen in all those countries that where under the thumb of the us-military, the day those soldiers do no longer get paid or get backup from overseas, in bases surrounded by people who have generations of grudges.
Definitely agree here. In addition, I am reasonably literate and understand all the uncommon words people use instead of everyday ones but I find reading windy prose is tiring. "I purchased a house", "we utilized the spoon", "Steve and myself are going to the pub" all sound a lot more clumsy and showoff-y than "I bought a house", "we used the spoon", "Steve and I are going to the pub".
If you have enough money, you can do some of both.
Win32 is even better: it will run on Linux and macOS, too, thanks to Wine and friends.
I figured it's one of those structs where the macro can resolve to a few different types depending on what's #define'd, but the implementation should still be able to use sizeof wherever it's needed.

I do believe there's a good reason; I just can't figure out what it is.

edit for any curious readers: I found an answer here
https://stackoverflow.com/questions/30416191/why-do-some-win...
The US did something similar around 15 years ago: has everyone forgotten when George W. Bush gave everyone $400?
The Greek Data Protection Authority provided some guidance on online tracking last month. In particular, the following was called out explicitly as a non-compliant practice:

> In the event of rejecting trackers, the user is constantly invited to make a new choice through a
pop-up window, while the same does not apply if the
user accepts trackers, in which case their choice is
maintained for a longer period.

https://iapp.org/resources/article/cookie-guidance-from-gree...

That's not necessarily same context, but the main point still stands: By law, if you're invoking "consent" as the legal basis for collecting and processing data, consent must be freely given and as easy to withdraw as to provide. Provoking people to change their mind from "no" to "yes" but not the opposite is not considered to be freely-given.
Which is exactly why it isn’t an overreaction.

Thanks to the lack of testing we have no idea how bad this is. And due to the severity of the worst case scenarios and relatively high probability of them be happening, in the absence of more information, an overreaction is indeed prudent.

That’s what people don’t get. Uncertainty often increases the need for more action, it doesn’t reduce it.
Would I have rather bought two weeks ago at 3000+ or today at 2400? Answer: today! The logic is that eventually the market will recover and you want to buy before that happens.
This is going to take much longer than that to play out.
Alternative to Google ReCAPTCHA – MeCAPTCHA
Have a google, I was using SSM for remote access to Windows instances, specifically headless instances.
YMMV. Some companies will not hire people that they feel are too entrepreneurial. Sitting in a cubicle and being happy is a much different mindset for someone who has run their own business before.
Its not fundamentally crazy.

In one sense, standard investing advice is to periodically rebalance between investment classes when your holdings diverge too much from you desired profile. In this, for a "simple" investor, that would probably mean transfering from bonds to stocks; since the portion of your portfolio that is in stocks recently fell substantially below your desired portion.

Assuming an efficient market, it is almost a no brainer that you should rebalance. Since your risk profile didn't change from a month ago, and stocks are being correctly valued, your portfolio is now overly conservative.

If you dont believe the market is effiecient, the question becomes 'in what way is the market inefficient?'. If you believe it is now undervalues stocks, you should buy them since they are now on sale for a bargain price.

Personally, my view is that the market is irrational, but I don't know how; so I am planning on not reballancing until after the dust settles. This minimizes the downside risk caused by me not knowing what I am doing.
I remember all of the statistical problems centered around virality that we would have to do in college. The problems always seemed so make-believe and dystopian.

Now my company is close to going out of business and I have just been laid off. Partly due to high-ranking officials not believing in the virality of nCov-19.

I can't get W.B. Yeats "The Second Coming" from 1919 out of my head:

"Turning and turning in the widening gyre
The falcon cannot hear the falconer;
Things fall apart; the centre cannot hold;
Mere anarchy is loosed upon the world,
The blood-dimmed tide is loosed, and everywhere
The ceremony of innocence is drowned;
The best lack all conviction, while the worst
Are full of passionate intensity.

Surely some revelation is at hand;
Surely the Second Coming is at hand.
The Second Coming! Hardly are those words out
When a vast image out of Spiritus Mundi
Troubles my sight: a waste of desert sand;
A shape with lion body and the head of a man,
A gaze blank and pitiless as the sun,
Is moving its slow thighs, while all about it
Wind shadows of the indignant desert birds.

The darkness drops again but now I know
That twenty centuries of stony sleep
Were vexed to nightmare by a rocking cradle,
And what rough beast, its hour come round at last,
Slouches towards Bethlehem to be born?"
> it goes against their personal values when dealing with other people

It's my impression as well that this is the main motive behind those reactions. I don't see why though. It's as if thinking about humans as actors in a model, or thinking about them as meat robots that aren't blessed with free will etc automatically makes you a Bond villain that want's to enslave humanity. I don't see how that follows. Understanding humans better, their behavior, reactions, emotions etc enables you to understand them, help them, make them happy, support them etc.

Re relatedness to loneliness: possibly. My personal observation is that most people who self-identify as lonely lean heavily towards intellectualism and wanting to understand things instead of emotionality and being happy with intuition. Naturally, they'd think (and write) about what they don't understand.

I don't believe you can turn that around though. Similarly to learning to read a language forces you to read a language (short of closing your eyes or looking away, you cannot escape recognizing and interpreting the characters and words that are in front of you), you can't just say "oh, so because I understand the world to function this way, I'm lonely? Cool, I'll just pick a different mental model of the world".
Bad parents are going to be negligent regardless of the circumstances.
How can I model the type of interaction between people. For example :is school a stronger vector of propagation than workplace ?

I ask because everybody in my country talks about what to stop (restaurants, culture,...) but never explain why working is considered less of a problem... (I have my little idea but well, ain't sure)
It may appear blaming Ms forever for their past actions is a good idea. It's not. Those actions and decisions came from certain people. They're long gone. I look only to the present. MS decisions and actions these past few years have been pretty solid imo. We must always assume the best of everything, not the worst. Not matter what. It may appear naive, but it's the only sane way.
UVXY?
I did search, didn't find it quickly. Could you share some sources of the negative impact? (I'm legitimately curious as my use of GitHub hasn't led me to notice any change.)
South Korea and China itself are the best models for countries that have (sort of) bounced back. And they leveraged a variety of mass mobilizations the US hasn't started with. So basically we're in for a LOT of pain in dealing this.

Exogenous shocks usually don't provoke recessions but is going to be like a planet-wide tidal wave. Things are going to be very different at the end. Huge, efficient enterprises may well end up even stronger but would the market for a given medium sized enterprise even make sense? We don't know.
The hard part of the economics of Covid-19
Atari 2600 had 128 bytes of RAM, even the KIM-1 onboard 6502 had a eight times that - a full 1K--the Apple I had 4K of RAM.

NES had 2K of work RAM + 2K of video RAM, compare to the C64 at the time that had a full 64K, or the newer 16-bit computers at the time like Amiga, Atari ST, etc. that were 128K, 256K or more.

SNES had 128K of work RAM + 64K of sound RAM. In 1991 I think typical computer memories were starting to get in the 2-4MB range.

Playstation 1 had 2MB of RAM and 1MB of video RAM. By 1995 you were firmly in the 8MB range or higher for PCs.

Playstation 2 had 32MB of RAM. My PC at that time had 256MB of RAM and that was somewhat low.

So the trend of consoles having far less RAM than PCs is well established.
The total lockdown system seems almost untenable as it is.

Let's say China has managed to isolate the virus to some pockets... that means the rest of China is not exposed and vulnerable for who knows how long.

The sheer amount of effort to prevent what seems like the inevitable might be wasted effort.

That's not to dismiss the casualties or the impact of a widespread outbreak or the desire to SLOW it. But man do you spend forever and all that effort isolating A from B & C ... and then B from A ... until there are huge amounts of vaccine available (late fall?)
To be fair, every western country has missed this boat as far as I can tell. People are similarly confused and angry in the country (in Europe) I live in even though the testing rate is far higher here.
You are correct in that there is less demand for travel, but there is still demand.

Without a car it's incredibly difficult to fulfill even a trip to the pharmacy with only a compromised public transportation system.
Cash transfer from wealthy individuals and families via the IRS.