skysight-inc/HackerNews huggingface dataset:
Then we have a treatment (i.e., zinc gluconate + chloroquine):

A zinc tablet (10-80 mg) dissolved slowly in the mouth, lavaging the throat and nose, while lying down will cease coronaviral replication on most of the surfaces of the upper respiratory system. Zinc sprays also work. This must be done within the first 3-4 days of infection with covid-19.

The covid-19 virus' usual course is to first infect the eye, nose and/or throat and then, after ~3 days, move down into the lungs.

If chloroquine (mg) stops the virus in the bloodstream then the combination of (dissolved zinc in mouth + chloroquine pill (up to 500 mg of chloroquine per day) should slow (if not stop completely) the virus, allowing time to clear the virus from the body without raising an excessive immune response ("cytokine storm"). But this treatment must be done within 3-4 days of contracting covid-19.

These medicines are cheaply available now.
True. But I have heard that that was because, among all the soldiers in the trenches, it could be virulent and still be able to spread effectively, so it had no selection pressure to not be virulent.

Covid is a bit different, because it has a longer incubation time, but that wasn't the issue with the 1918 influenza outbreak.

(Note well: I am not an epidemiologist.)
The US, like most other countries, is only a couple of days behind Italy.

Italy had 100 total cases only ~20 days ago.

The problem with this virus is that it goes from 1 case to hell in only a couple of weeks. If you already have 100 confirmed cases, it's too late to stop what's coming.
A more up-to-date, although not complete, comparison is available here: https://caniuse.com/#compare=firefox+74,chrome+80,safari+13
I know what 'bait and switch' means, just like I also know what FUD means.

Next you'll call them Micro$oft. Come on now.
Research firm warns Bitcoin investors of extreme volitility sparking sell off
No, what's happened is they've already changed to a lockdown strategy, as the link above details.
> Keep in mind that, if it comes to it, California can declare martial law to maintain order.

Isn't that the right thing to do? You can't have martial law forever. On the other hand, this set a precedent for government to reduce liberties when they see fit.

I'd much rather see a martial law.
One perspective is that people are tired of getting the short end of the stick. Yet again the young incur an outsized proportion of the cost while the old reap an outsized proportion of the benefit.
Maybe they want a flat curve in the sense of a rectangle. You know rapidly rise until just what the system can take and then keep it there..
There’s a huge demand for the service they provide and they’re trying to do everything in their power to satisfy it. I doubt Mr “Your margin is my opportunity” will fail to reinvest almost all of the profits either.

Can’t we leave this bullshit to when it seems like a problem again, instead of meaningless background to the plague, while our loved ones die, economies implode and daily life is wrenched into new shapes?
He looks like Lex Luther.
I'll just sit here on my municipal bonds, thanks...
Ah yes, an article written by a scientist with lots of data.
This is the full text: https://www.sfdph.org/dph/alerts/files/HealthOrderC19-07-%20...
It’s odd but really true. Does anyone have insight why this is the case?
Why wouldn't you want your search engine to use what contextual information it knows about you when attempting to provide you quality, relevant answers to the questions you're asking it?
How Long Will macOS Be Unix?
I don't see why not. Unless they are literally within weeks of dying already, in which case they probably weren't leaving the house anyways.
The other way around, and in fact it already is that way -- we often say stuff like "Waymo, Google's self-driving car project", because we know who really runs the alphabet show.
Their population demographics are different from ours.

We will continue to provide workers and consumers over the coming decades - economy-wide demand will return once the crononavirus threat subsides.
Covid-19 data hub: the White House issues a ‘call to action’ for AI researchers
> hate shrinking scrollbars

IMHO there are many things to dislike about 'modern' GUIs!

Back when Windows was a relatively new concept common sense things like making buttons stand out and using colour and borders to group and organize features. These things have pretty much gone out the window. Everything is a flat homogeneous dark scene.

/rant
Paranoid thought - what if it's on plastic or exposed steel on something inside the package (like the wrapping on a box or an ladle that doesn't come fully enclosed in a box), you need to wait three days or so.
Nothing wrong with that, but it seems reasonable to me that once a company goes public (or hits a certain size), it no longer makes sense for one individual to have such a large stake in it no matter how essential.
Public transport is a hub for diseases no matter how well it's designed. You really need a personal transportation vehicle that isolates you from others.
Western cities are extremely disgusting and dirty compared to Singapore, Tokyo or Taipeh.

The moment I step out of a train arriving at central station it smells like piss and a bunch of drunk homeless people perform a spitting contest.
Assuming immunity in the recovered population, R0(25% immune) = 0.75R0(~0% immune)
Don’t know for China but there are couple sources and cases for Japan.

What I think a most plausible explanation is it takes time after symptoms disappear for our immune system to finish wiping out virus. Influenza also has that stretch, though only days long, not weeks.
Same day shipping not sounding so great now!
Rule of thumb for any sound situation, live or recorded: give yourself a limited palette so you can sound consistent.

If you want an album to sound like it's all one piece, you use the same instrument and processing for it all the way through -- except for that one time that you want to highlight it.

In visual terms, you want the grass on the left side of the painting to be the same as the grass on the right side of the painting, unless you deliberately want to say something about the grass. You should only be drawing people's attention to what you want them to be looking at.
All the IRC servers in the world couldn't support all the traffic discord gets in a typical day no matter how the load was distributed.

According to Wikipedia [0] Freenode has less than 100k users spread across 32 servers. The group of Discord channels (confusingly referred to as a server) for Roblox players has 300k [1]. The Chill Zone server, which doesn't have a topic and where people just chat, has 150k members and over 6 million messages in it's "#general" channel, and the discord server for the /r/teenagers subreddit has 21M in its "#general" channel. These constitute a tiny fraction of the number of text messages being sent over discord, which itself probably uses a tiny amount of bandwidth compared to the constant pictures and files being sent, not to mention the voice and video calls.

It's easy to have 100% uptime when you have a product so user-hostile that nobody uses it. Yes, Discord is an electron app that probably spies on you, but users don't really care about that compared to being able to read messages sent when their computer was turned off or getting notifications on their phone, etc.

[0]: https://en.wikipedia.org/wiki/Freenode
[1]: https://top.gg/servers/150074202727251969
That's a much rarer course and seems to be related to the conditions of WW1. Under normal circumstances, people with mild illnesses are out and about and able to spread the virus, while people with severe illnesses are confined to a bed or hospital and tend to result in an evolutionary dead end. As a result, the descendants of mild cases outcompete the descendants of severe cases, and eventually natural selection results in the dominant strains of the virus all being mild.

With the 1918 flu pandemic, mild cases of flu remained with their unit, while extremely sick cases were transported home via train for improved medical care. As a result, it was the severe cases that ended up sparking new infections, while the mild cases died out after generating herd immunity within an army company.

Most respiratory viruses follow the first scenario, although there is a caution there for people who suggest eg. transporting sick people by airliner to regions with fewer cases to make better use of available hospital capacity. Ironically asymptomatic transmission is your best friend here: if all transmission is asymptomatic, the strains that get transmitted will be the ones more likely to not cause symptoms.
Does anyone know how these are enforced?

Especially since the order says Violation of or failure to comply with this Order is a misdemeanor punishable by fine, imprisonment, or both.
You are wrong about South Korea. Their testing has been incredibly effective from the beginning, patient 31 in South Korea had no known contact and was told to take a CV test by her doctors, but didn't take the advice until a 2 days later.
https://graphics.reuters.com/CHINA-HEALTH-SOUTHKOREA-CLUSTER...
Super beginner question - as somebody holding some Swiss cash on top of some basic reserve, I understand now it would be too risky to enter any stock/other market. I am a pessimist in expectations what will happen - rather gloomy state of affairs for next year or so, no fancy vaccine/quick tests etc.

Here is the question - what investment vehicle, if any, would you consider for looking into when wanting to presumably enter this situation in say 4-5 months? Ideally say some medium term returns, not benefit after 30 years.

Sorry for possibly annoying question to the experts, just looking into some guidance
I'm not here to debate you on anecdotal data (I know 5 people off the top of my head who do use it).

It has a respectable 10,000,000+ installs on the google play store and ranks high on the apple store with 270,000+ reviews. Though not comparable with the likes of WhatsApp (which I personally use and prefer), I would not dismiss it as 'not' a mainstream option. We can agree to disagree for sure.
Okay. I personally do not have the financial reserves to bootstrap something like this, though if someone else does, I by all means wish them luck.
The fourth estate is the media [0].

For anyone else who was unfamiliar with that term.

[0] https://en.wikipedia.org/wiki/Fourth_Estate
Great job putting out an entire self produced album and documenting it. I wanted to bounce this opinion off you.

Its my opinion that most folks who are going to be using programmed drums would be better off with an inexpensive MIDI controller with some pads (like the one pictured in your article) vs playing them on an electronic kit unless they happen to be a very skilled drummer.

I play drums passably, but when I'm demoing up ideas I just thump them in with some pads on a MIDI controller.
No actually it will be. It will be gone from the planet more or less within months. Corona viruses don’t mutate in a way that invalidates immunity gained from exposure to its ancestors. The flu does that but corona viruses do not. And there is no evidence that this one is an exception. Herd immunity will be achieved and it will stop spreading.
AFAIK the UK line has consistently been "we'll do it, but not yet, because we can only do it for a limited time and so far the numbers don't warrant it". That's not a U-turn, that's doing pretty much what you said you were going to do.
Don't think y our 1-1/R0 rate makes sense (I assume Re is equivalent to R0 - I'm not familiar with Re). At an R0 of 1, each person spreads to one other person. So everyone would eventually be infected, just at a linear rate. Your formula though gives 1-1/1 = 0. Similarly for an R0 less than 1 your formula goes negative.

Anyway, if R0 can be brought below 1, it wouldn't need to be indefinite. The further below 1 it is, the faster the virus will extinguish itself. This was seen in China, where they went from exponential growth to fewer new cases each day and ultimately to the situation now where most new cases are imported from other countries.

You also don't need global coordination, although it helps. Any individual country can restrict outside travel from outbreak areas, get their own R0 below 1 via social distancing to eliminate the local outbreak, and then relax social distancing locally, relying on travel restrictions and temporary quarantines of travelers from outbreak areas, plus testing and contact tracing. If cases start to flare up again, increased social distancing measures can be brought in to get them back under control.

So in theory you could do extreme distancing for a period on the order of a few months, and then normalize somewhat. It would take a global response of that sort (unlikely), a vaccine, or a change in the virus itself though to end the situation entirely.
Universal Becomes First Studio to Offer First Run Films in the Home
I have to think that the government/police have very little interest in harsh and perfect enforcement. As long as most people mostly follow the order -- and likely most will, because they're not all engineers who like looking for loopholes in everything ;) -- it will help. Better is better, but pretty good is better than nothing.

The order also allows going for walks as long as you're not with someone you aren't housed with, so the misdemeanor part is likely to be about gathering, not travelling.
It's not that simple. First of all, most people do not develop permanent immunity to the cold which is usually one of the first 4 known human transmissible corona viruses. So there is no reason to think we'll develop long term immunity to this one either.

Second, our reaction has be abysmal which, similar to the 1918 Spanish Flu pandemic, massively increases the chance of a second or even third wave of massive infection spread. That will be on many peoples's minds.

And one more thing I want to touch on so people here can get it through their thick heads: just because the death rate is supposedly "low" and "only" impacts old people mostly, that doesn't mean it doesn't impact YOU. If YOU have an emergency and the hospital is packed with COVID-19 patients, it doesn't really matter what you have, you are affected.

Even ignoring the ethical implications of just letting people die from this, I think most people who would do that are unlikely to ignore implications to themselves so figure out where you land or not, it doesn't matter, the goal of keeping hospitals from being overloaded affects everyone.
That's not true: driving results in between 3 and 12 times fewer deaths per passenger-mile than cycling, depending on your methodology. [0]. Even if you take it to be only 3x and compare per passenger-hour rather than per passenger-mile, which nobody ever does, you would find they are roughly equally dangerous.

[0] https://bicycleuniverse.com/bicycle-safety-almanac/
That wall clock would need to handle different month lengths somehow because the month ring can be 28, 29, 30 or 31 days, and provide for a way to add years to the outer ring.

Probably regarding months, it would likely do what a lot of mechanical watches do: go to 31, and require manual intervention to set the day of month.

That's kind of ugly because you have to rotate that wheel exactly to retain the fractional part of the day, which is hard to accurately other than at midnight.
They aren't rumors. UK ICU capacity is already overwhelmed.
Roughly 250k Canadians cross the Canada-US border per day. Not sure about US citizens.
Yes, the flight isn't going to happen. The EU will close all external borders for 30 days tomorrow at noon. If she is a citizen of Germany and doesn't have any symptoms, she can expect a seat on a repatriation flight. Contact appropriate embassies.
Impossible Foods raises about $500M in new funding
Yes but the law of diminishing returns is especially prevalent, here.

For a serious, scientific, by-the-numbers mixing technician, the amount of quality increase versus the amount of time spent more often than not hits a massive bell curve fairly early on - particularly if it is not that technician’s original material.
Good point regarding aggregations, especially if done at ingest time w/rollup they really make a big difference. Clickhouse has aggregations too but they are done at merge time in the background.

Vectorized query engine and JOINs sounds awesome.

(We did meet in SF! Beer hall!)
> A surprising number of people commenting that this is an overreaction. I suggest reading this[1] and this[2] before you're so hasty to dismiss this. This is absolutely the right move (and if anything should have been done sooner).

> Also luckily the comment ranking here seems to mean your peers disagree with you.

> [1]: https://medium.com/@tomaspueyo/coronavirus-act-today-or-peop....

> [2]: https://www.flattenthecurve.com/

I've noticed these discussions all revolve around problems related to the virus. However, these quarantine measures are also economic in their nature and I'm not seeing even the standard university economics professor trotted out in front of the press to support why this is all going to be okay.

If you are concerned about old people, consider that their investments go belly-up, their pensions funds dry up, their house goes negative equity, and they cannot physically work. How bad is for them after this happens? Because this is what is going to happen with the economy shut down.
there won't be any paperwork because there won't be any insurance. even your congress and senate realizes this by now. it's an unworkable proposition - you either bankrupt the 10-20% patients which require hospitalization or you bankrupt insurers. you're in for a revolution in healthcare.
Easier to trace who was on a plane with other infected people. You're not aiming to stop all infections, but to be able to slow, contain, and trace.
Yes, this has always been possible. Just specify the tarball url instead of a version or range.
It's not a problem if you can't see it!
Not exactly. Up to 20% of those tested thus far required hospitalization of some kind of another. This in no way means 20% of all infections will require hospitalization. But right now, we don't have great data, other than estimations, of how many people currently have been, or are, infected without being able to test everyone.
Which doesn't make a Zagnut bar an agent that has power, does it?
This reminds me a situation of a product I am building, copying an existing one, turns out the original decided to go out of the market. More details:

https://news.ycombinator.com/item?id=22512596

https://telegra.ph/Announcing-atbswp-a-minimalist-keyboard-m...
Here's how China claims to be handling day-to-day life: https://m.youtube.com/watch?v=YfsdJGj3-jM

Basically, masks in public, no-contact thermometers everywhere, and QR codes that you scan to enter a subway or a building. There's more, but that's the core.

If you have a fever, then they send you to a specialized fever clinic: https://mobile.twitter.com/MikeIsaac/status/1238604080571772...

There, they determine if you've been infected. If you have been, they send you to a group isolation ward, where you spend a few weeks chilling out and doing group dance exercises. If can't stand up and dance, you get treatment.

It's clearly a society at war, and I'm sure some ugly details are hidden. But it looks better than hiding indoors while our medical system burns and our elderly relatives die (and at least some of us younger folk wind up with scarred lungs).
Apparently 30% of cases of the common cold are cause by coronavirus. And the worrying thing is that the immunity we acquire for those is only temporary.
Thanks for the link, I've started reading it.

The complexity of defining and determining "actual causality" is a good justification for mathematicians' avoiding the whole thing and using material implication instead. As most of you already know, material implication A -> B ("A implies B") is a boolean operation, which is the same as ((not A) OR B), see https://en.wikipedia.org/wiki/Material_implication_(rule_of_... . Material implication avoids all this complexity.. but because it's simpler, it cannot by itself represent our notions of causality. Material implication even has some "weird" surprises, e.g., "All Martians are green" and "All Martians are not green" are both true when defined using material implication. I created an "allsome" quantifier to deal with this problem: https://dwheeler.com/essays/allsome.html . But it'd be nice to learn about other alternatives, so I started reading this.

I've only started reading this book, but the approach does seem a little odd. Its definition of causality embeds a model, which has embedded causality in it. In section 2.1 https://www.cs.cornell.edu/home/halpern/papers/causalitybook... it notes this issue: "It may seem somewhat circular to use causal models, which clearly already encode causal relationships, to define causality. There is some validity to this concern... Nevertheless, I would claim that this definition is useful."

I don't have a better idea, and I can see the value in making the use of models clear. But it does seem to weaken the idea of defining causality. Is this considered reasonable? Is there a possibly better approach?
This same argument process--that to "flatten the curve" in the way all the cutesy diagrams show isn't going to be sufficient to avoid chaos unless we maintain social distancing for years, and that we are deluding everyone into thinking this is "the solution" and that life is somehow going to go back to normal in a couple months (which is where most of the people I know--normal people, not all of my super paranoid friends ;P--are with their mental timelines) to the point where we are not concentrating any effort on anything else (to the point where believing "flattening the curve" is some panacea is maybe even a "dangerous delusion"), including capacity expansion and explicit tracing--was made by someone in an article on medium a few days ago. The prior article had the same little modified graphs showing the true problem, but had actual math to back up their back of the envelope calculations for why it will take years. FWIW, that article was shat on... hard... by people here on Hacker News, and was even flagged, because people even here are apparently so bought into the narrative that they take arguments that it isn't sufficient as somehow "so don't do it: social distancing is bad" (which is bullshit, and not what either of these arguments were/are saying). It is absolutely frustrating how much of an uphill battle it is to even get people to analyze this stuff quickly: we keep having to wait until things get notably worse and then we are willing to look at something only slightly more drastic. I have had friends making this same argument for like a month now and everyone just treats them as if they were literally insane or something :(.

https://news.ycombinator.com/item?id=22575356

https://news.ycombinator.com/item?id=22581950
It is functional alright. Here is an example:

California has tested 8,316 people total so far [0]. My province of Alberta has tested 8,887 people [1]. This is even though the population of my province is 11% of the population of California. In fact, the population of California alone is higher than the population of Canada, let alone my province.

Put it another way, California has tested 210 people per million residents. Alberta has tested an order of magnitude more, 2030.

Edit: Today's numbers for Alberta are in. Alberta has completed 10,598 tests, or 2,425 tests per million population.

[0] From https://covidtracking.com/data/

There is some uncertainty about the number, but not so much that the real number would be an order of magnitude higher.

[1] https://www.alberta.ca/coronavirus-info-for-albertans.aspx
I haven't seen any statistics, but it appears that Rita Wilson and her husband contracted it in Australia from what I've read. That was the more worrying thing to me about that news than the celebrity connection.
Interesting concept as a way to raise awareness. Do you have any plans to further develop it?