skysight-inc/HackerNews huggingface dataset:
Coronary Sinus Neuropeptide Y Levels&Adverse Outcomes in Patients W Stable CHF
Also consider combining w/ K2 (as MK-7) for better absorption.
I personally first saw it in this tweet translating the Welt article[0] and after looking into it other sources seem to agree.

For what is worth, in Germany's case, in particular, there is very little concern with them not sharing the vaccine, but I can see how the US might think it can profit by having exclusive rights to it initially..

0. https://twitter.com/nicktolhurst/status/1239117898901266432
« Typo was as surprising inside as it was outside. Its similarity measure was based on trigram frequencies, which it counted in a 26x26x26 array. The small memory, which had barely room enough for 1-byte counters, spurred a scheme for squeezing large numbers into small counters. To avoid overflow, counters were updated probabilistically to maintain an estimate of the logarithm of the count. »

This sounds like something from the same family as hyperloglog

Wikipedia traces that back to the Flajolet–Martin algorithm in 1984. When would typo have been written?
There's a difference between sickness-causing deficiency and optimal level. Most people are somewhere in between. If you tried and it didn't make a difference, then you're probably around the optimal level.

However, the specifics do matter; see e.g. https://www.gwern.net/zeo/Vitamin-D - this is n=1 but consistent with many other n=1 self-experiments I'm familiar with; personally, my sleep is improved with increased protein consumption AND 10,000 IU D3 before 10AM (Both contribute; I've not gone about 10,000 IU, but 5,000 UI has a much lesser effect)

I have not find a peer reviewed time-of-taking-D3 paper when I looked, but D3 is recognized as a timing mechanism ("Zeitgebber") in many papers I've found.
There is also a human factor: most people don't like living in the same cage where they work 24 hours a day

Family life is mostly about sharing the events of the day

Working home is pretty uneventful and that aspect can be stressful

I worked home for 13 of my 23 years career, loved them and still do it, but my best years have been the 3 years I left all my jobs to go touring around Europe as roadie

Being part of a team that shares a common goal but also solves everyday mundane tasks together like finding a place to eat that's ok for everybody or fixing a flat tire gives a lot more meaning to what one does
Here is my issue. I take what he says, and assume it’s not true. This works over and over again. T works so well, I default to this for everything he says. It makes things much easier to understand. Unless something gets fact checked as true, this serves me well. I didn’t start like this, but this is where I am. And I haven’t run into a situation where it wouldn’t have served me well.

Sometimes, I trust what he is saying. It has always proven to be worse for me to have done this.

Say what you want, but this is far worse than a web site that isn’t 100% on day one and designed by law. That site has worked for a long time, but the actions taken on this misinformation is permanent.

And as well as you think he’s done, he’s made it worse. Through policy decisions to calling it a hoax, he’s worked hard to make it as bad as possible without doing nothing.

When people are discussing where people can find food because they didn’t stock up enough and grocery stores are sold out, that’s pretty unreal. A hoax doesn’t go to something real in less than a week.

This is crazy. You hear orange man bad. Yeah, that’s because he legitimately is doing a bad job. Your standards are just in the dumpster. And honestly, don’t blame you. That’s where is actions belong.
You can definitely overdose:

https://en.wikipedia.org/wiki/Hypervitaminosis_D
Understanding HTTPS and PKI for busy folks
On the other hand, Italy has very good food hygiene standards, as anyone who has been told off for touching the fruit and veg in the grocers can tell you. You never have a shop assistant handle money and then touch food, which you see all the time in the UK/US
Ok, let's think this through.

You buy a weapon and try to intimidate the armed aggressors with your weapon.

They actually know how to handle weapons and shoot you as soon as they see your weapon because they know how dangerous these things are.

You're now shot and are either dead or currently bleeding out.

How did this improve your situation exactly?

Escalating conflict is not necessary in your favor. It can be, but its way more likely to backfire than help you
... to aid efforts, we call on the government to release their modelling data to allow scrutiny from the scientific community to better predict the course of this outbreak

It is possible of course that at the moment, no such thing exists to standards expected by members of the British Society for Immunology.
There is a third one, the ones that cause billions of monetary losses in fixing security exploits.

It was a big mistake from US government to have forbidden Bell Labs to be able to sell UNIX on its early days. C only got widespread because it had a free beer compiler and OS to back on.
It's a language problem. Things like self quarantine of infected (and potentially infected) people have a big impact on how fast a disease spreads (meeting the bar for "effective" in my mind).

What they don't do is completely stop it.
Ah, in American it’s usually considered to be the street itself…
I have seen this said about almost any non-mainstream language from Haskell to Perl.

I think it comes down to these languages are mostly used by enthusiasts on their own projects, without the daily realities of evolving business requirements and a legacy code base built by mediocre developers.
Thanks, Nikolas000 for sharing!
Agreed - I believe the meta-analysis and the underlying studies are likely of poor quality.

I think it might be worth for people here to reanalyze everything.

The effect sizes seem large and clinically significant.

So this is big if true.
I see lots of praise for Singapore and Taiwan's handling of the crisis.

What about the weather? Is part of the solution for cold dry places to have warm humid weather, which apparently kills the virus?
Elm has syntax errors stylized in this manner, but I am not sure how much is only rephrasing of usual "expected" or something more elaborate
Sure, but there's a TON of out-of-band data in voice that cannot be easily replicated in text, that's a fact.

Voice tone, pitch, pauses, irony, sarcasm (both easier to misunderstand in text), etc.

And in person or voice chat have the highest signal-to-noise additional data stream that is body language. "The mouth says yes, but the eyes say no."
do you ever heard of plague?
No need to kill it per se, it would have been enough to allow Bell Labs to sell it at the same price as VMS, OS/360 and other competing mainframe OSes, instead of distributing its source code for symbolic price.
I recently learned that it is possible to buy shortwave airtime on reasonably strong stations for around 30€/hour. I don't have a concrete project yet, but I think there could be some fun projects to be done with this.

Here is an overview of stations that sell airtime:

https://www.reddit.com/r/shortwave/comments/5mocm7/sw_statio...
I really don't see the issue. All vitamin d sales come with daily dosage information. There's (always going to be) some issues with literacy to understand this information, but that's it.

If you follow the daily dosage information, you won't even get near harmful levels of vitamin d. Recommended is about 600 IU daily. If you take 60.000 on a daily basis for months, you build up toxicity.

For that you typically need to take 30 pretty strong 2000 UI pills on a daily basis for months, while ignoring the label that states each pill is typically 250% of the daily recommended amount, and the instruction which notes the tolerable levels max out at just two daily pills.

Toxicity is extremely uncommon. Whereas deficiency is extremely common. Up to a billion people are expected to have some form of vitamin d deficiency.

That's not to say it's not a problem, but rather that it's very rare, nothing like say an opioid overdose problem. As with all things, balance is key. You can overdose on 5 cents of water in the span of 5 minutes. Acute vitamin d overdose is known to happen if you take something like 300-1000 pills of 2000 UI over a period of days, which is pretty insane.
> some people have since obsessed about

The burden is on the government to better unify the messaging in a time of extreme uncertainty.
If you take a lot of vitamin D, you have to make sure that you are getting enough magnesium.

Also, vitamin D really shouldn't be taken any other time than before noon.

(Not sharing this for you in particular, just for anyone reading who decides to try vitamin D supplementation for the first time. Doctors aren't always sharing she vital info about how to take vitamin D)
When US injects 1.5T into the markets, it seems a lot like the US theoretically can absorb 1.5T of goods and services from the rest of the world with money that didn't exist the day before. It seems absurd if true. Can anyone with knowledge on the matter clarify?
Do you actually need someone to answer this for you, or are you arguing in bad faith?
Toilet papwr, bananas and carrots were all gona at my local store. I got everything else I'd planned. I'm not panicking about TP. I spent like $45 on a couple more bidet seats for my house and we're all using them. It's more environmentally friendly and I don't have to worry about hoarders.

We've had a bread machine for a while, so we use that a lot. We don't have cow milk in the house anyway. I have pet chickens and if we need to, we can eat the eggs. We have a mostly vegetarian diet and the meat alternatives aren't flying off the shelves.

Just need to find some carrots and bananas...
For anyone else unfamiliar with A2 milk:

> A2 milk is a variety of cows' milk that mostly lacks a form of β-casein proteins called A1, and instead has mostly the A2 form. [...] The a2 Milk Company claims that milk containing A1 proteins is harmful [...] but a 2009 European Food Safety Authority (EFSA) review found [no] an adverse effect on health.

It is said to be sold mostly in five eyes countries and China, which would explain why I've never heard of it, and is snake oil to boot so I'm happy it hasn't caught on here.

> The a2 Milk Company claims that people who experience discomfort drinking ordinary cows' milk may experience relief when they switch to milk with predominantly A2 protein. This claim is not supported by research.

Scum of the earth. I'm actually pretty sure that health claims that are not supported by any evidence whatsoever are legal in the EU (edit: found it[1]). Curious that it's still popular in the UK, but it probably got popular in the past and they just stopped printing that claim on the packaging when that became illegal.

> The EFSA study emphasized the dangers of drawing conclusions from correlations identified in epidemiological studies and the dangers of not reviewing all the evidence at hand.

I'm sorry u/vmarsy, but you've been mislead about what A2 milk is :/ The placebo effect might work and have real effects, but buying (more expensive, or just any really) products from scammers still seems ill-advised.

All citations from https://en.wikipedia.org/wiki/A2_milk

[1] https://en.wikipedia.org/wiki/Health_claim#European_Laws
On the subject of conference cameras I can fully recommend the Logitech BCC 950 (https://www.logitech.com/en-gb/product/conferencecam-bcc950). It's ideal for work from home and you won't usually need to use headphones with it. On the downside it's pretty expensive.
There's a certain irony in accusing someone of constructing a strawman by constructing your own strawman.
That is the fucked thing about cancer. It is never over. Even if you come up clean in a PET it is always still there. Lingering. Forever..

The mental game after you recover is nearly as bad as the actual treatment. When I was between scans I did fuck-all because I could be dead in a month so I will just watch reruns of "Come Dine With Me".
#4 is now implemented. Thanks again for the suggestion.
>without providing any reason or evidence or justification

Calling something 'problematic' doesn't in any way prevent you from providing a justification for that view. If people aren't providing justifications when they should, then that's a problem independent of the particular choice of words.
I know exactly how you feel, I'm right there with ya!

You might enjoy some of the clips from recent days in Stockholm, where a massive cargo ship just delivered a bridge from China: https://m.youtube.com/watch?v=tRF88r8JNI4

To really appreciate the scale, here's a flyover picture: https://www.instagram.com/p/B9ogNmzACKV/

The ship left yesterday, but public service television is still streaming live from the area, and you can see the previous days there too with the ship arriving, unloading the bridge etc: https://www.svtplay.se/guldbron

Sadly I can't find an english version of the site, but it should hopefully be easy enough to navigate anyway.

I've really enjoyed streaming this channel the past few days, it's had a nice calming effect for me in the middle of all the covid19 chaos.
It's important when megadosing vitamin D to be getting enough magnesium, and to make sure you're taking it earlier in the day, so as not to disrupt your circadian rhythm.
> So the next best option is to spread the peak by alternate phases of more or less strict social distancing.

Has this been done before anywhere on a large scale?

How is it done, do they just say "it's safe, you can go back to work now wink wink", do they encourage virus parties like new-age-parents? Are they going to convince the public that everyone should get infected in their allotted wave for the common good? Will they go door to door and just shoot in a blast of viruses? Won't people catch on if they alternate between strict and lessened isolation rules and figure "they're trying to trick me into getting infected, I'm not going back to working at the office, thanks"?

I absolutely get the idea, but it's not like you're dealing with a population that has it's memory reset every morning and just acts on the information available today.
My B12 was so high I had to lower my supplementation twice. Now I only take the spray every two weeks to allow my values to get down. But even on that dose my values are at the very top of the reference range.

The problem with B12 is more with low cobalt in the soil and genetically low absorption. There are now even bioactive plant forms of B12 like water lentil.
Yes. Compact cars are usually 1.8m wide, subcompacts are usually around 1.7m, and bigger cars are about 1.9m. 2m puts a Tesla Model S in "midsize van" territory. Thats the size where you start having problems in some spots. For a private car, that's impractical.
During my early government grant years, I did not buy new t-shirts nor jackets. It's almost a requirement for every conference or new grant program to order shirts. I even got one heck of a winter jacket because someone in DC decided we needed winter jackets. I guess it all constituted acceptable publicity.
> Hidden inside WWB (writer's workbench), Lorinda Cherry's Parts annotated English text with parts of speech, based on only a smidgen of English vocabulary, orthography, and grammar.

Writer's Workbench was indeed a marvel of 1970's limited-space engineering. You can see it for yourself [1]: the generic part-of-speech rules are in end.l, the exceptions in edict.c and ydict.c, and the part-of-speech disambiguator in pscan.c. Such compact, rule-based NLP has fallen out of favor these days but (shameless plug alert!) Writer's Workbench inspired my 2018 IOCCC entry that highlights passive constructions in English texts [2].

[1] https://github.com/dspinellis/unix-history-repo/tree/BSD-4_1...

[2] https://ioccc.org/2018/ciura/hint.html
https://en.wikipedia.org/wiki/Ratfor

The original Ratfor brings FORTRAN 66 nearly up to the level of a respectable programming language.

It turns this:

if (a > b) {
max = a
} else {
max = b
}

Into this:

IF(.NOT.(A.GT.B))GOTO 1
MAX = A
GOTO 2
1 CONTINUE
MAX = B
2 CONTINUE

... with proper columnization, of course.

Going the opposite direction is pretty miraculous to me.

Ratfiv is the follow-on, which did the same to FORTRAN 77. However, FORTRAN 77 had control structures beyond the conditional GOTO, so Ratfiv was somewhat less necessary.

FORTRAN 77 would look like this:

IF (A .GT. B) THEN
MAX = A
ELSE
MAX = B
ENDIF

https://en.wikipedia.org/wiki/Ratfiv
The flip side is that when you are stuck in a busy noisy office, the only place you want to be, is at home to concentrate and do your work. Stuck at home too long, and need the office. Balance.
It's hard to appreciate without first understanding how our genetics work. That is, the mechanisms that are responsible for replicating our genomes and turning our genes into proteins.

Viruses are an inevitability because they exploit vulnerabilities in those mechanisms. Viruses are not alive. Instead a virus causes "live" modifications to a living organism which causes it to simply reproduce more of the virus. When you have a virus you are essentially one with the virus; a modified organism.

Retroviruses go one step further by permanently making that modification. Now you are forever modified with the extra functionality of producing more of that virus.

But the really beautiful thing is how minimal these viruses are. If you've played code golf you'll appreciate it. In the smaller RNA viruses like influenza and HIV, each virion carries around exactly what it needs to make those modifications and not much more. They consist of proteins which cause our cells to accept them as well as the genome which causes our cells to make more of those proteins. They also cause our cells to reproduce the genome itself too. Eventually the cells become full of virus stuff and somehow the viruses assemble themselves back into virion, the cell dies and releases the new virions.

The HIV genome is incredibly compact. It's the closest thing to design I've ever seen in biology. It packs more information into its genome than would normally be possible by utilising overlapping genes on the forward and reverse strand. It's quite remarkable just how clever, minimal and perfect it is.
Huh, shouldn't the things on the right hand side of the colons be types not values?
Tic-Tac-Toe in Python
Some trees root more deeply than spreading out horizontally. Simply leaving more room around the green strip helps too.

Brickwork sidewalk might bend a bit more smoothly than asphalt or concrete slabs... or at least it should be more repairable without tearing everything out.

> Also on some pavements the trees cause bottlenecks because its too narrow for two people to pass eachother.

This indicates that there's simply too little space allocated to the sidewalk + trees.
Explanation by the director of F@H on twitter: https://twitter.com/drGregBowman/status/1238930030585143297
I'm so glad the tech bros, here and on twitter, are on top of this epidemic.
I don't trust the professors of medicine and scientists advising our governments either if I can't see some Python code and a condescending tweet about how no one understands exponential growth.
Who says that B12 supplementation works less good than eating meat? The last studies I read on supplementation all showed good results. Better results than among omnivorous people.
Suppose your company is developing a framework for creating mobile apps. You work on optimizing the GUI renderer and you are assigned a task to make a module which finds computationally equivalent render functions (or a company making a programming assignment plagiarism system, or a duplicate config file detector when the config language is accidentally Turing-Complete).

You may try removing whitespace, finding invariants, ordering the variables by type, converting for loops to while, tail call optimization, but your collegue always has a trick to make equivalent functions undetectable by your module. You were solving the halting problem. Instead, you should use CS knowledge and tell them it's impossible but they can have a non-optimal search. Perhaps, the fastest way to complete the task would be to score similarities between the functions' machine code or AST.
> Also, vitamin D really shouldn't be taken any other time than before noon.

I'm sure I could go find sources, but it might be helpful if you link them here. It's hard to believe comments that give medical information and disparage doctors.
Why magnesium? Any references?
Seems like a lite, streamlined Second Life to me.
The InboxSDK website does not work in Firefox (tons of JS errors, and visually it looks like it vomited a bunch of oversized images all over my browser window).

How could anyone trust a company to do a good job working with really complicated web technologies, when they can't even do a simple website to advertise their product?
I believe that the paper backing the tool came out in the 70s, but if I ask IEEE for it it gives me back an awful PDF of one page that constrains a poor scan of the cover page of the paper and nothing else so I can’t confirm whether this idea was in it. Perhaps you might find more success: https://ieeexplore.ieee.org/abstract/document/6593963
Sure and I didn't say those obsessives were to blame. In fact, I'm going to say blaming anyone is a waste of our efforts right now.

Edit, maybe by 'burden' you didn't mean 'blame', exactly. It is part of the government's job to communicate properly and it seems they didn't get it right. But we can accept that and now be open to the explanations of what they really meant. So we can get on with what matters.
This thing understands Finnish? Very strange. TLDR from this was quite excellent: https://sarastuslehti.com/2020/03/12/koronaviruksen-kayra-on...
The "common cold" is a catch-all phrase for many different viruses, which are not all closely related to one another. The coronaviruses that circulate in humans (other than SARS-CoV-2) are common colds. My understanding is that they do not mutate quickly, but that for whatever reason, one infection does not confer lasting, complete immunity to later reinfection (though later infections may be less severe).
Churchill is not exactly a good example of solid decision making.
Every time I see a post like this I get the urge to get myself a ham licence, then always realise that realistically I'm never going to join a club in order to do so. I wonder if the authorities might consider, in these interesting times, letting people sit a foundation test online. Seems like it might be a prudent idea.
The fatality number is irrelevant. We know it overwhelms health systems, and there's no ICU capacity to handle it.

That's all you need tk knoe.