skysight-inc/HackerNews huggingface dataset:
There are many papers online giving confidence that 50-80 mg zinc (gluconate) reduces colds by a day or two and 1000-2000+ IU vitamin D3 reduces flu by a day or two. So while I disagree with your conclusion that Chloroquine won't work, I wish I could give you 100 points for making the connection between zinc and RdRP.

Edit: just did a search and your insight led to this study on zinc and Coronavirus from 2010:

https://journals.plos.org/plospathogens/article?id=10.1371/j...

Abstract

Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing. In this study we demonstrate that the combination of Zn2+ and PT at low concentrations (2 µM Zn2+ and 2 µM PT) inhibits the replication of SARS-coronavirus (SARS-CoV) and equine arteritis virus (EAV) in cell culture. The RNA synthesis of these two distantly related nidoviruses is catalyzed by an RNA-dependent RNA polymerase (RdRp), which is the core enzyme of their multiprotein replication and transcription complex (RTC). Using an activity assay for RTCs isolated from cells infected with SARS-CoV or EAV—thus eliminating the need for PT to transport Zn2+ across the plasma membrane—we show that Zn2+ efficiently inhibits the RNA-synthesizing activity of the RTCs of both viruses. Enzymatic studies using recombinant RdRps (SARS-CoV nsp12 and EAV nsp9) purified from E. coli subsequently revealed that Zn2+ directly inhibited the in vitro activity of both nidovirus polymerases. More specifically, Zn2+ was found to block the initiation step of EAV RNA synthesis, whereas in the case of the SARS-CoV RdRp elongation was inhibited and template binding reduced. By chelating Zn2+ with MgEDTA, the inhibitory effect of the divalent cation could be reversed, which provides a novel experimental tool for in vitro studies of the molecular details of nidovirus replication and transcription.
You dropped a zero. There are 1000 MB in a GB, so your cost of running a Gbps line at full tilt is more like 3.6 cents per hour.

In other words, bill everybody a dollar per month for bandwidth and worry about it only if average usage per subscriber goes over 10 TB per month.
If amateur ventilators are only used when ventilation is required and standard ventilators are not available, that still may be a good answer.. still, I am sure that there are better and worse designs for amateur ventilators, it would be best if someone who knew they were doing reviewed various designs and could recommend the best of the bad situations.
I would assume that you will have basic utilities without interruption -- water, electricity. Supply chains could, theoretically, have disruptions as the disease runs through the world. I am not saying they will; just that they can. If it happens the affect on you and yours of not having extra is extremely significant. That's enough of a reason to buy what you can.

You cannot go back and time, but after things settle down (they will) look at your budget and what it takes to have a couple of weeks extra of necessary items. It's not super expensive to buy rice and beans if you are on a budget, then rotate your supply when the rice starts to get old. If you have more money you can get something with less monotonous flavor: canned food, dehydrated, freeze dried, whatever. You may need it twice in your life, but when you do, it will be the wisest thing you have every done.
What sort of stack do you all use then to manage these clusters? Have you found any solutions to your conflicts?
Ok, true. Many people have a big freezer.

Although not in Europe were the virus is about to peak in the coming two weeks. The average freezer and refrigerator is much smaller here.
I know this is usually the case (having worked a few years with molecular dynamics) but would be really interesting to get your opinion on what could be done better, where the bottlenecks are (tools or knowledge or just CPU-power) etc. Would you mind sharing some thoughts here or get in touch for some chatting?
ECS back and forth, part 8: Type Id
If you’re interested in fiat currency and the fed, I highly recommend the book Lords of Finance. The author does a really good job of showing just what central banks do and how their responses to economic events shape outcomes. The book entirely focuses on the Great Depression and the central banks of the USA/Europe but it’s really well written and really helped me appreciate what the fed does.
Thanks!

I'm ultra confused about their marketing btw. Their website doesn't even say it's open source. You have to sign up to "try it now". It's like they don't want customers? Or are people who want to understand what they're buying not the target market, somehow?

For reference, this appears to be the Salt primer: https://docs.saltstack.com/en/getstarted/system/index.html
> Use the almost undocumented `exc_info=True`

Why not simply use logger.exception()?

try:
do_thing()
except Exception:
logger.exception("It broke.")

Called from within an exception handler, logger.exception() automatically includes exception information.
"we also need someone (President? eCelebs? etc) to promote and organize fund raising"

Fund raising won't help if too many people get infected.
What you need right now is for those in charge to stop playing Rambo and pretend they have it in control (they don't) then grow up, tell people to stop behaving like there is nothing going on. Schools, stadiums, all non vital businesses should close and people should stay home.
This virus propagates at very high speed; as for now there is no cure, and I'm sorry for believers but prayers won't work (ironically, "healing" pools at Lourdes are already closed since days).
This is serious, folks. We can only slow infections to a level in which people recover at faster pace than those who get infected, otherwise ICU numbers won't be enough and a lot more people will die.
> Can anyone just make a SuperTux game?

It's GPL licensed so you may distribute derivative works under the same license.
I interpreted the parent's comment to mean that it could just be an artifact of the small size of the country. After all, there are almost certainly cities in the US where hundreds of teenagers have recently decided not to do drugs, but it wouldn't impact national statistics at all. If hundreds of teenagers in Reykjavik decide not to do drugs, it looks like they have "solved" the problem.
Yes, I think some of that complexity was due to interference by Atari, they definitely took a dump on the Handy/Lynx by changing the power circuitry and the size of the unit.

From what I've read, the joypads were lifted straight from the panther, as were the launch games, rather than be redesigned.

The CPU was always meant to be 32bit with a cache, Atari chose the 68000 for ease of porting games over, but cheaped out rather than choose an EC68020 which would have increased the bus bandwith by 4 times.

Same with a lack of a CD unit which if it had come with one would have helped attract developers - the costs of ROM carts made it very unattractive for most dev houses.

Additionally, having the designers do a proper SDK would have helped, especially with the direct memory access bug which would be mitigated with an official workaround.

Lastly, the chipset was designed to be able to use 2 memory banks, so having 1meg+512K would've been better than 2meg on one bank.

Obviously having more time to develop the chipset would have been benficial. I believe Atari insisted on the object processor in addition to the DSP and blitter, which the designers were not keen on, and really by that time had been demonstrated to be a bit of a dead end (Atari GTIA->MARIA->Copper vs tile/sprite-based VDPs or blitter-based processors). If they'd not put one in maybe the chips would've been ready earlier/better, or could've had some cache/registers for the blitter.

Even without the chipset improvements, a handful of changes would've made things a lot easier for developers, and faster to boot.
Its easy to judge other people without knowing their situation.

It depends on where you are, and how far the virus is in your country/state/city/region.

It also depends on if you can order groceries online and have them delivered. Though there might be extra costs attached and there's possibly environmental impact I believe this to be the best method to avoid further infections. If you prepare to have the virus, or to avoid getting it, going less to grocery store and making sure you got a supply makes sense.

We're currently ill (probably not COVID-19) and my daughter of 2 had diarrhea and vomiting. I made sure she got enough pain relievers, because our supply was running out.

There is also a large difference between buying a little bit more supplies, and buying very large amounts...
This. Take your slices out of the freezer in the evening and you get your good bread for breakfast or later the next day.
From what I learned, for production use of WebRTC, a specialized signalling server (STUN/TURN) is needed to reliably coordinate communication among peers - in particular, to deal with network address translators (NATs) and firewalls.

Most open-source WebRTC implementations I've seen use a list of semi-public STUN/TURN servers, notably including Google's, which I believe are explicitly for dev/testing purposes.

In addition to this "discovery layer" - and possibly handling reconnections - I imagine it's non-trivial to provide video/audio transport, compression, etc.

I'd love it if it were simpler to use WebRTC, truly peer-to-peer, in the vein of how early Skype used to work. Unfortunately, from what I've learned so far, there are still technical hurdles to self-host such a service.

https://en.wikipedia.org/wiki/STUN

https://en.wikipedia.org/wiki/Traversal_Using_Relays_around_...

https://en.wikipedia.org/wiki/Interactive_Connectivity_Estab...
I say this also from a place of kindness and compassion: you should heed OP’s advice.

My sister owns a pharmacy. She has been sold out of many things since end of January and isn’t receiving stock even though she orders it every day. She is starting to run out of canned foods. Her shelves are empty for many things. This is in Toronto, the largest city in Canada.

The next step will be complete shut down for 2-4 weeks across the US and Canada in order to “flatten the curve”. Expect that supply chains will be impacted and food will run out not because of lack of actual food but disrupted supply chains and sick workers.
This is why we (as Europeans, Dutch) bought an American fridge. So we can store large amounts of food. We buy certain things when they're on sale, in large amounts. There's much less choice available of American fridges (especially if you have other requirements such as amount of dB). It saves us money on the longer term.
I think in those cases the store owners should be responsible to not let that happen. They are basically doing 99% of their customers a disservice.
Calling any country a “shithole” place is a terrible insult for its population.
I'm skeptical that it will work out that way, because the infection tends not to disable people under 50, and I think most of the people involved in supplying groceries are under 50.
Structs are values and you can return them like any value (or use them as parameters).

I'm not sure what you mean about compilers.
Yes it is a panic. If you've seen some of the photos of supermarkets where people are rushing to grab everything before anyone else and there's stuff scattered all over the floor.

It's poor behavior, illogical, and doesn't help the situation. This isn't armaggedon, it's a slightly worse flu and if you're not old (70+) or immunocompromised you're going to be fine. Anyway, if you're 70+ getting a flu is bad news in any other year (60k people in the US die every year of flu!), nothing really changed except every flu death is now front page news. This isn't a zombie apocalypse, people are blowing this massively out of proportion.
This is a correct answer.
Famous iOS apps are snooping on the Pasteboard
Nonsense/linkbait
Any book on International Finance, to start. And then maybe a Banking 101 to understand how banking works. Then Macro Economics, to know how economics of markets and countries work.

There's no quick fix to learning this stuff.

However you might still want to; so take this biased Internet-clip with a grain of salt and enjoy: https://www.youtube.com/watch?v=mII9NZ8MMVM
We are not going to run out of most groceries. The primary advantage of stocking up is to make it possible to stay home.

If you don't have Covid-19, staying home limits your risk of getting it and then passing it on. If you do catch it, having enough supplies to manage a mild case at home also limits the likelihood of passing it on.

As long as community transmission is low in your area, stocking up today in order to be able to stay home for the next couple of weeks seems to make sense.

This is a collective fight. The average person can aid the global effort through the simple effort of avoiding in-person human contact. (Reaching out electronically can help us feel connected, too!)
They call it panic buying because it is irrational and driven by fear of the unknown. Don't know where you live but in every country/region with a covid-19 epidemic had any shortage in the production/supply chain of food or other first need goods (and 2nd/3rd need either but some of those shops did close) and it doesn't look it's going to happen. It's not a post-nuclear scenario nor a "get touched and you are gonna 99.9% die" disease either. So yeah, people is panicking.
this is a worldwide problem at the moment.
All you've convinced me of is that the + operator isn't defined for characters. Which makes sense. Trying to tell me that something called char is really just a byte in disguise (while true in some popular languages) is just irritating and misleading to me.
Firefox has: https://developer.mozilla.org/en-US/docs/Tools/Taking_screen...
I have never loved Linux.
I recommend: ‘The Origins of Economic Disorder’ by Fred Block, and ‘The Vega Factor’ by Kent Moors.
House of Morgan - biography of JO Morgan and kin

Snowball - biography of Warren Buffet

The Good Earth - novel about Chinese farmer

Fortune’s Children - the rise and fall of the Vanderbilts
Well done. But here's the actual thing:

There will always be those who don't like using the mailing lists for back and forth reviews and the same goes for GitHub (I use both anyway and have a self-hosted community GitLab and cgit). This isn't about me, its about attracting potential contributors to the Linux kernel in the long term.

If I were tasked to attract as many beginners/students to go this path, It won't be to start with the Linux kernel or the LKML mailing lists (that will put them off). It would ultimately be other beginner-friendly similar projects like SerenityOS, HaikuOS or some of the BSDs even, etc so they can get some experience. Then their mental model is used to the Git flow so they can transition to using bare Git commands and can go into a technical discussion involving anything about kernel internals.

Since Linux doesn't need to worry about attracting new outsider contributors due to commercial contributors doing most of the work, little needs to change. Which is why from the very start I much rather recommend beginners to start with other OSes and transition later to Linux internals.
That would be mind-blowing to me.
> I hate it when people call it panic buying. It's not a panic.

Yes, it is, for some non-trivial percentage of the people doing the buying. There are also people who are stocking up in a more rational way, but those are irrelevant except in the sense that their rational strategy is being thwarted by the panic buyers. It's not necessary for everyone to be in a panic before the phenomenon can be considered real.
> I hate it when people call it panic buying. It's not a panic. People are preparing themselves to have food for 2 weeks. That's what you should do as well.

People have been loading up shopping trolleys with literally hundreds of rolls of toilet paper. Easily enough to last a year. If that's not panic buying, I don't know what is!
> The UK has some of the best epidemiology schools and experience, thanks to a tradition harking back to the British Empire expanding in very dangerous lands.

This is not an argument in 2020. This is the kind of exceptionalism i m talking about
I’m saying that using a leading indicator like the stock market is no metric for declaring that things are getting better.

Trump going up there and making a bunch of positive statements means zero right now. The public and private sectors have no reason to trust the federal government during this situation.
Just FYI, I live near Seattle, and the grocery stores around here have been out of many things for a week. I'm sure they've been restocking in the meanwhile, but we haven't been able to get a few things.
While it's true the over-preppers hurt everybody, I think you're overestimating how many of them there are and how directly they caused the dearth. Grocery stores simply aren't prepared for everybody buying even just two weeks of food at once.
Money Stuff is great, and explains things quite well, generally, but I think for a beginner in the field it presupposes too much. It dwells on the amusing arcana, the esoteric warts of the system often, that you only appreciate once you have a certain base level understanding of the industry.

Lastly, it’s fairly focused on the investment banking side of things (derivatives, capital markets, IPOs, the finance industry), not so much on the monetary system, macro, and institutions.

On banking and banking regulation, making a case for higher capital (=equity) requirements for banks, The Bankers' New Clothes: What's Wrong with Banking and What to Do about It by Anat Admati and Martin Hellwig is a good read [1].

I can’t think of a good book on money and the various theories about - if someone has a recommendation there, would be great.

[1] see here for a flavour of it https://www.jstor.org/stable/j.ctt1r2dn0
By that argument, why even have types... and what makes bytes so special? Perhaps you'd like to work with bitstreams, (or qbitstreams)?
No, not at all. Just pointing out the unsanitary situation that is the norm for these countries.
Sure. Its more that your CICD is lacking.
Somewhat meta comment, when I read all the conflicting recommendations here (seriously, for almost all recommendations there’s an anti-recommendation somewhere in this thread), it makes me question the value to me in really trying to understand the financial system.

I mean, I’m not completely financially illiterate. I understand compound interest. I stick with sinking most of my money into passive investing, saving x months of expenses in checking for surprises, and not accumulating any debt.

Every now and then I think about getting back into value investing (it was fun in high school) which is a little more active, but the effort required to understand this system seems enormous/impossible. There are simplified expositions of how to read a balance sheet, but then I run into weird edge cases of financial trickery that I’d never be aware of. So I figure I can’t compete with pros and passive investing seems like a reasonable enough approximation in the long run.

When I compare it to all of the other stuff I could learn or skills I could acquire in the same time, so far “learning about the financial system” is so messy and uncertain to me that I never really pursue it.

Has anybody run into this issue? What did you decide?
Thanks for the recommendation, I'll look into it :)
There's certain foods which are useful to have in larger amounts, and there's certain foods which are perishable. It makes sense to ensure you have some supply of the former, and it makes sense there's on short-term a higher demand than supply for these. For perishable products, it does not make sense, though I myself own for example a dehydrator with which I'm able to ensure perishable foods become less perishable.
I work in fintech and I've been reading Matt Levine for a few months now after seeing his name pop up here on HN several times.

I agree with everything you say.

> He's engaging, funny, talks about interesting topics and, most importantly, he's _rarely_ wrong. It's a rare thing seeing a journalist talk about your specialty subject and actually being correct.

More importantly, on this point, when he is wrong, he freely acknowledges it, embraces it, and then corrects himself in a way that demonstrates he's more interested in truly understanding the topic and updating his cognitive model than in "being right".

Thursday's column is a case in point, where he owns up to two mistakes:

https://www.bloomberg.com/opinion/articles/2020-03-12/the-bu...

He's also the source of one of my favorite quotes on the last tech bubble. From his 8/7/2019 column, on MoviePass, borrowing from Dickens:

Annual income twenty pounds, annual expenditure twenty pounds ought and six, result misery. Annual income twenty pounds, annual expenditure three hundred million pounds, result unicorn.
They have an announcement on their web site[1] and on twitter[2].

Also the web client shows information about the executing tasks (e.g. [3][4]). The COVID19 tasks are prioritized and will be executed when you keep the target settings of the client at default ("Any").

[1] https://foldingathome.org/2020/03/10/covid19-update

[2] https://twitter.com/foldingathome/status/1238568504200253442

[3] https://apps.foldingathome.org/project?p=11749

[4] https://apps.foldingathome.org/project?p=14329
I was sick couple of weeks ago and symptoms were very similar to Coronavirus and my doctor dismissed the need to get tested for Coronavirus because I didn’t travel to any of the hotspots. I am feeling better now but I will never know if I had the virus.
Its weird you're only looking into logging exceptions.

At previous companies we setup logging to record all kinds of actions from end users, including possible errors/exceptions.

But as you figured, metrics are the end goal.

I've previously setup mtail to create metrics from log messages and that gives me 90% of what I may need from logs at a fraction of the cost, speed and time.

But logs are still useful for exploratory ad-hoc analysis, or the less common patterns which you're not monitoring or creating metrics for.
> Being able to sit in on board meetings, and talk during them would be enough, not necessarily having a vote, maybe thats a special adviser?

Big multinationals typically have advisory boards / subcommittees that advise them on certain topics. I assume Microsoft has a technology advisory board (and in their case, likely several) that includes at least some high-level engineering talent.

Leadership at the board level involves high level decision-making, but not a lot of actual work. The CFO of PepsiCo has a ton of responsibilities himself; his position on the board of Microsoft is likely only a few hours a month because it's limited to reading reports prepped by the C-suite and its advisors, then voting on decisions. Senior executives and investors are chosen for boards because their day jobs require an understanding of market context and a good bullshit filter to guard against the Jobsesque pitchman scenario.
It's not "Visual Basic". At best, it's a basic done in the same "spirit" as Visual Basic.