skysight-inc/HackerNews huggingface dataset:
>> If you think you only need to budget supplies for two weeks, you’re just wrong. You need to budget for _months_

Can you back this up at all? As I explained in my comment, Italy, one of the worst hit countries globally (and on 'lockdown') has grocery stores still functioning. The idea that people will be required to not leave their homes for months is fear mongering , impossible to enforce, and even in the worst case scenario people simply won't do it - they'll go stir crazy and give up a lot quicker than they think.
The cobas 8000 is huge: https://www.youtube.com/watch?v=Aht-L4BMyN4
Ask HN: Fighting Covid-19
Hello, everyone. If you want to help fight the virus, there's some things you can do. You can donate your computing power (your gaming PCs preferably) to https://foldingathome.org/ and https://boinc.bakerlab.org/, and you can also get your hands dirty and try to design a protein that inhibits the virus on https://fold.it/. It doesn't matter what's your background, it might be you that finds a viable solution.

If you know other people that have some spare computing power on their hands, or some available time and are willing to take a shot at the most critical puzzle of the moment, please share.

---

I have some questions for the community (this is why this is an Ask HN):
- are there other ways developers can help in finding a solution?
- is there some kind of programmable way to accomplish what fold.it does, with comparable ease? it would be very nice to be able to express the protein as code, instead of manually designing it with the mouse.
- do you know some good resources for people to learn from scratch how to design solutions for this? much of what is available is for specialists in the field, but maybe there are some easier to consume tutorials / references / handbooks

Additional resources:
- https://twitch.tv/FoldIt
- https://www.rcsb.org/news?year=2020&article=5e3c4bcba5007a04a313edcc
How is this some sort of prescient statement? There have been movies made about this exact issue for decades. On a societal level, it is a bug marked WONTFIX similar to preparing for asteroid impact, the next Big One in SF (come on guys, we arent prepared for it), the next volcano, large scale terrorist attack using chemical weapons, and so on.

It seems nobody has a memory to remember that Microsoft hobbled local governments attempts to build and use open source software instead of paying their tax. In a way, you’re basically thanking Bill Gates for redistributing a small fraction of the money he’s stolen from global governments through the Microsoft monopoly.

If you think this is a conspiracy theory go talk to IT staff who worked in the German government in the late 90s.
Yeah it's not just you. I bet most people will close the page in 1 second if they don't see a screenshot (including myself).
Where are the customers yachts? - but basically if you get the title you don't have to read it :)
By the exact mechanism in the article above, penalizing price-gouging?
"use the government's influence to artificially prevent the price of the product from rising"

How would that work? If Dollar Tree were fully stocked with hand sanitizer, I would go there right now and buy 10 bottles. But so would 99 other people. So we 100 would get all the 1000 bottles, and everyone else would be SOL.
While that is in fact the stated reason for the law against price gouging, that rarely happens in the real world

What does end up happening is something (like a outbreak or natural disaster) causes a regional shortage of a good, which is often extended because there is no real incentive to divert goods to fill the shortage.

Today that if often mitigated because of large national companies like CVS, Walmart, Lowes, Home Dept, etc who will move their supplies around based on normal prices

But in some situations Mr. Bill that owns the local store may have an excess supply of Good X, and would be incentivized to move them to an area of shortage if the price was higher. With Price gouging laws he will not bother.

Further Increasing in prices also in some ways allows for people with the greatest NEED for the items to actually get them, and discouraging hoarding.
At G scale you could never afford to run something as grossly wasteful as chef. It would be cheaper to have several full-time engineers maintaining a dedicated on-host config service daemon and associated tools, than it would be for some ruby script to cron itself every 15 minutes.
I highly recommend listening to Duke professor Mike Munger discuss price gouging on this episode of Econ Talk:

https://www.econtalk.org/munger-on-price-gouging/

It’s very entertaining and enlightening.
The Status of the Sovrin Foundation
But if we created it at the dramatically and artificially increased demand that it has right now, it would be disastrous for that industry once this panic subsides. Imagine the increase in infrastructure these companies would have to build to keep up with this fake supply. The workers, the real estate, the building of supply chains and machinery. Now imagine what happens to that industry when suddenly the market's demand tanks back to a reasonable level, and there's suddenly not only far more capacity for production that is now unprofitable, there's a huge backlog of supply already in the hands of consumers.

This situation is just as bad for the manufacturer as it is for the consumer.
You could, alternatively, convince them that they don't want that much toilet paper. For instance, convince them that stores will not run out of stock and that they will be able to go to stores. This is the normal state of the toilet paper market. The problem here is not that we've suddenly been possessed by demons who want infinite toilet paper, the problem is that people are making rational decisions based on actual facts on the ground changing. Some of those rational decisions are "I'm worried I won't be able to get what I need because I hear that stores are running out." Other rational decisions are "I think I can make a profit on this because of upcoming scarcity." ("Rational" is not a value judgment.) If you can prevent people from believing those "because" clauses, they'll stop demanding it.

Also, price-gouging laws do not "stop the market from giving them what they want." If anything, price gouging does - if someone who has $100 in savings wants a year's worth of toilet paper, they're less able to successfully get it if the market can run unchecked. It's true that an unregulated free market is good at getting products sold at the best price for the sellers - that's very different from giving people what they want.
I recon it didn't receive attention, because it's a trite observation, not prediction.

"It's not if, but when there will be another recession."

"It's not if, but when there will be another pandemic."

"It's not if, but when another asteroid hit the Earth."

We live in the real world, things happen more than once.
Many crypto miners are indeed doing F@H at the moment. Either via curecoin[1] or by lending/joining their rigs to one of the teams[2].

[1] https://curecoin.net

[2] https://folding.extremeoverclocking.com/team_list.php
You can freeze bread for weeks, maybe even months and even preserve freshness.
Training a Rap Machine
I suggest you google "rationing" because that's exactly what happened in during World War II.

https://en.wikipedia.org/wiki/Rationing_in_the_United_Kingdo...

Not just in the U.K., rationing was also introduced in the United States during wartime:

https://en.wikipedia.org/wiki/Rationing_in_the_United_States
Plan for the big peak, hope for the small one. There is no indication that leadership in the US is going to suddenly start behaving sensibly.
>I would argue that the supply/demand pricing isn't responding fast enough

Yes, that's a failing of the real free market we live. It already failed so I don't see why suggesting the status quo is useful. In the real world we're not all omniscient, rational actors. Protections like this are useful in the short term.
Web of Debt by Ellen Hodgson Brown.
If going experimental, Camostat and E-64d are better choices to blockade ACE2 and TMPRSS2. Chloroquine has much more serious potential side-effects including irreversible, rapid macular degeneration where someone might reasonably prefer not to continue living because of them.
Random Walk and Black Swan are two good reads. Even if you end up not agreeing with the two's takes, they'll make you sufficiently skeptical of how well a book claims to explain the industry, which is a good position to approach it from.

My bias will show, but the industry routinely blows itself on sometimes small or sometimes very large scales, sometimes or often through devices of its own creation. It's important to know that the system is entirely capable of doing this to itself, and therefore the system, and those in it, may not be able to explain itself well.

Edit: another thing worth reading is Too Big to Fail, The Big Short, and Greatest Trade Ever. All are engaging books, and really walk through how 2008 started and ended through different perspectives of the system. TBtF will cover the Fed and Tier 1. BS/GTE cover the sell side. And then when you pair GTE with what happened to it's focus, John Paulson, after 2008, in that he didn't really have a repeat 'win,' it's a good anecdote for what I said above.
That’s a debatable point but the fundamental economic structure of society is sound. Free market capitalism won, wins, and will continue to win.

But like I said - Venezuela and Cuba are hurting a lot. They need good comrades to help them. Please emigrate there and help fix their societies by donating your labor and knowledge. I just don’t understand why more people don’t move there to help! You seem like an ideological comrade that could help them, please go there quickly.
>What becomes of that toilet paper when this fear has subsided?

It doesn't expire? People just use it up, and don't buy more until they've used all their store.

>What becomes of the companies that had to scale production, create new factories, hire new workers etc... when the existing glut of supply is not only so much that those new facilities are hurting them, but also that it has decreased the demand for their product even with normal production capabilities?

They only would have made the decision to scale production if they estimated the profit from filling this short-term demand would make up for the cost of having to eventually scale back the temporary investment. It's not exactly hard to predict that the demand won't last forever.

Ultimately the amount of toilet paper bought/consumed isn't going to change significantly, just the purchase dates will cluster together.
How is this different from pipelineand feature union
One response from a particle phycisist to this story can be found over at the PhysicsForums[1].

A couple of the main objections:

First, I consider having theorists publishing based on preliminary experimental data bad practice and borderline unethical. The experiments say "we're not sure and we're checking this", and the theorists go full speed ahead, often putting words in the experimenters' mouths.

Now, let's look at what happened. The experiment ran in 2015 and saw no events. Then the accelerator and detector made some configuration changes (hoping that they would be improvements) and got 1.5x as much data. They see 4 events, one of which they say is certainly background. They also say that the known backgrounds sum to 0,05. So just looking at background, they see 20x as much as they expect. Clearly the backgrounds are not yet under control. Declaring an observation of signal when the backgrounds are not under control would be scientifically irresponsible, which is why KOTO did not do that.

[1]: https://www.physicsforums.com/threads/rare-kaon-decay-may-sh...
Men Sentenced to 125 Years Each in Drowning of Syrian Refugee Boy
Trying to ward off the coronavirus? What products help and what may be a waste
Example: How do you do "immutable" management of Mac OS machines? Taking what's typically described as such there, you've just turned a 30s deploy of software into a multi-hour "lets reimage the entire machine"?

(although that's of course not strictly "old stuff")
When hikers or travelers are beginners, have you seen how much more (or not enough) they pack? With experience or guidance they tend to pack lighter.

In the current case, some are concerned, some are waiting to survive a doomsday, some watched the Contagion movie, some are hoping to make money.

A sane way: For Covid-19, one has to be prepared with basics(food, water, soap, fever-reducing-medicines) for somewhere between 14-27 days of home quarantine (or curfews). And not just assume by default that administration will crumble - they are usually there when you need the basics, except for countries where it has been proven otherwise. Many things that people are stocking up are non-essentials i.e. replaceable with other less comfy methods.

After this is over, the govt. administration can attempt to advertise/educate some preparations for the next unforeseen times. Over a longer period that becomes a cultural habit.

I do not understand why people take unprescribed medicines, especially antivirals as prevention, when that could clearly disturb human microbiome and open up for infections.
I don't think I'm overestimating. It's all anecdotal, but I'm hearing things from friends, seeing lots of instances on social media. The NYT just covered one of them: https://www.nytimes.com/2020/03/14/technology/coronavirus-pu...
Informed consent of X or X's health POA determines what happens, not random doctors.
> Perhaps the law we need is one to control hoarding behavior or the rate of change.

You know what would control hoarding? Higher prices.
All government decisions, quick or slow, are driven by self interest
https://assets.publishing.service.gov.uk/government/uploads/...

Look at Matrix A - global pandemic listed as both likely and impactful.
https://en.wikipedia.org/wiki/Medical_ventilator

https://en.wikipedia.org/wiki/Forrest_Bird

we really are talking about two things here, one being the equipment used, the other being the therapeutic specialist that has to attend the ventilator, and tune it to chase after a multivariate dynamic.

ventilation can cause lung injuries and facilitate lung pathology this is part of a trade off for overall wellbeing.

a ventilator has to be able to manipulate pressures with near instant response and very high precision.

during natural ventilation there is sensory feedback allowing nearly point for point modulation of flow and cycle. ventilators dont have this. Coronavirus aside It would be good to find some way of getting around the risk of lung injury
Why would you buy 10 bottles? What are you going to do with them?

Are you afraid they're going to run out? Why? (Put another way, why aren't you buying 10 bottles of drain cleaner right now?)

One of my local pharmacies had hand sanitizer in stock for $3 and no obvious limit on purchases. I bought one, because I needed one, and I expected that (because my locality had announced anti-price-gouging laws) I could go back and buy another one if I needed it. But it kind of lasts for a long while.
> there's no cytokine storm with COVID-19.

Could you provide a source?
Why does the author think Sentry isn't logging, and can't have side effects? Very strange article. Starts with principles I agree with: don't log unimportant events and when you do log send everything you need to understand the problem... and then goes well off the rails.
Sounds like you may be interested in Pulumi: https://www.pulumi.com/
I think that <stabbing you> is best considered as a form of free speech. A <sharp knife between the third and fourth intercostal space> is a statement of the value of your argument.
Also heat. Wires bunched up tight can’t cool themselves down as well.
I’m not the one saying that, Italian experts are saying it, because it increases the level of bafflement they experience when looking at the (non-)approach the UK is taking at the moment. I am extremely critical of this (non-)approach, I’m just trying to figure out where it comes from and this might well be a factor, sadly. After 2016, I’ve learnt never to underestimate the often-misplaced sense of superiority that the English upper classes have drilled into the wider population for the last 200 years, and the degree of detachment of their elites.
The manufacturers aren't stupid. If they're capable of running a profitable manufacturing company they're capable of realising the demand won't last forever, and not investing an amount that would cost them too much when the demand dies back down.
Based on my expertise from watching the movie Contagion, one possibility is that a sick bat flew out of the jungle into an open-air pigpen. The bat dropped a food scrap. A pig ate the scrap. A chef later handled the butchered pig. He shook hands with Gwyneth Paltrow during a kitchen tour. She then mingled with many people in the restaurant.

My original mental picture of the Wuhan market was that something weird was happening there, like people swallowing snakes live or doing a ritual with boar tongues. The movie scene demonstrated how a sequence of unremarkable steps could also do it.
We're society, and we value needs over wants.
Yes absolutely.

Some of the people involved in the early QUIC development in Google had been heavily involved in the SCTP work and blamed its lack of success on the difficulty in getting firewalls, middleboxes (and the teams that manage them) to accept a new IP protocol. So they wrapped QUIC in UDP.
Not a downvoter but my guess is posting "I've got at idea" with zero details and a request for people to contact you is not the type of collaboration people here want to encourage. Others with ideas are simply posting them here and receiving public feedback on them.
This reminds me of the financial crisis in 2008. A ton of people knew what was going on and issued warnings but not many listened. What I don’t like is the effort to make some people like Gates into heroes that saw what nobody else saw. Public health experts warned for decades that we are not prepared but nobody wanted to pay for action.
Ask HN: Non-cloud voice recognition for home use?
I'd like a home-based voice recognition without some off-site cloud.

I'd like a kind of echo dot like thing running on a set of raspberry pi devices each with a microphone and speaker. Ideally they'd be all over the house. I'm happy if they talk back via wifi to a server in my office for whatever real processing. The server might have 16 cores and 128Gb ram. Might even have two of these if required.

What options do I have? What limits? I'd really prefer answers from people who have experiences with the various options.

If it helps I'm happy to reduce vocabulary to a dictionary of words as long as I can add more words as necessary. Training is also ok. I've already analysed my voice conversations with an echo dot and the vocabulary isn't that large.

Please remember: home use, no off-site clouds. I'm not interested in options involving even a free voice speech-to-text cloud. This eliminates google voice recognition, amazon etc. They are great but out of scope.

So far I've identified CMU Sphinx as a candidate but I'm sure there are others.

Ideas?
The winking smiley was meant to give it away as a joke.. because the parent's final statement doesn't actually mean anything (because it still justifies any behavior... including the one being attacked)
... Stainless Steel proteins. Can you fathom proteins made from carbon? They would be very easy to break and unsustainable..
VB uses the same syntax for array indexing and subroutine invocation, but they aren't the same operation; you can't define a parameter that is either an array or a subroutine. So the extra expressive power that this unification provides in K is absent in VB.
yes. unless i'm doing something wrong.
Even still...

https://en.wikipedia.org/wiki/Real_Irish_Republican_Army
> They only would have made the decision to scale production if they estimated the profit from filling this short-term demand would make up for the cost of having to eventually scale back the temporary investment. It's not exactly hard to predict that the demand won't last forever.

So what you're saying is, they wouldn't have scaled production, so your entire proposition about why the price increase would be an effective means to alleviate the problem was false.
Free markets do not promote ideal behavior. Morals do!
Links for 8th:

* Home: https://8th-dev.com/

* About: https://8th-dev.com/about8th.html

* Previous discussion: https://news.ycombinator.com/item?id=15672361

First I've heard of 8th, but my immediate reaction is similar to the comments in the HN discussion :/
“How is this some sort of prescient statement? There have been movies made about this exact issue for decades. On a societal level, it is a bug marked WONTFIX similar to preparing for asteroid impact, the next Big One in SF (come on guys, we arent prepared for it), the next volcano, large scale terrorist attack using chemical weapons, and so on.”

Exactly. A lot of people know the risks but we are not willing to pay for preparedness.
Sounds like it's mostly an SV thing then? A lot of things are handled very differently out there.
That does not prevent hoarding

The idea that people are hoarding right now simply because they want to resell the goods to others is moronic on many levels

People are hoarding right now because they believe they may be months with out a supply of the good, so they are buying in multiples of normal levels fully expecting they will use it themselves, not reselling
Since you mentioned steak, have you tried a vegan diet? Dairy and meat contain hormones that might affect you. Neil Barnard has written about that, if you're interested.
A number of great Keybase features have only appeared recently which may be why there's a mismatch between the blog post and Keybase's current features. In the last few months there's now:

* Ipad support (nascent but works)

* Bot integration (VERY interesting permission structure https://keybase.io/blog/bots)

* Neat SSH CA
It's full of people intelligent enough to understand how incentives and consequences work, and mature enough to be able to accept that some possibly immoral people might benefit for the greater good.
> If you look at other things like alcohol use, things don't look good.

What? Why is alcohol not regarded as a drug in this kind of research environment? Is the aim of this research to save teenagers from drug abuse, or is the aim to have lower numbers of illegal-drug-abuse?

Overall, this seems questionable at best. Not letting teenagers spending unsupervised time surely has ripple effects in most, if not all, areas of society, the most of which I'd consider highly undesirable (not granting autonomy leads to severe psychological issues down the line)
Samsung Galaxy S20 Ultra 5G (Why People Secretly Love)
Get a flu shot, wash your hands, and stay away from large groups and don't exercise to exhaustion during periods of peak transmission.
I fully understand rationing, rationing is something done by Authoritarian governments, including the US and the UK...

So it seems you are infact proposing authoritarianism as a solution to the problem

Give up freedom for safety... wonderful. I see alot of that right now it is very sad
> Or did you merge it to master, and will be living with that added complexity during everyday development

One place I worked, we had a demo version of the product's web interface, and this is how we did it. Maintaining it wasn't fun, and people didn't pay much attention to it so it started to rot. We eventually removed it because marketing switched to something else because it was so bad, but I'm wondering if there's another way.
List of publicly available DNS over HTTPS servers
I assure you, the machinery is pretty damn standard on the whole Earth.
Yes. Great bread recipe linked below. You may never go back to store bought. It has non-laborious kneading, you just leave it overnight.

http://chefmichaelsmith.com/recipe/country-bread-city-bread/
Train for a Mars mission: survive social distancing while WFH with your kids