skysight-inc/HackerNews huggingface dataset:
The main cost isn't per sample, it's the amount of time the machine takes to sequence enough fragments of RNA to achieve statistical significance. If you combine samples and want to not miss anything, you need to run it for longer.
At 91-1 it doesn’t mattter whether he does or does not. Hope he gets the aide out and spent though.
> Folding in fixes for common issues which were found in newer releases sometimes involved more than just cherrypicking the fix into a patch release for an older version.

Honestly? This isn't an a problem of accidental complexity that some combination of tooling and process can fix for you. I don't think that anyone has kept the cost as low as log(N_releases). Even that would be too high for most teams.
I feel your pain... Reminded me how quite similar it seems to be for hospital staff: alternating night and day shifts, extra long shifts like 24hr of continuous work. When asking "but how can you deal with it and know you keep working properly at all time?", answers consistently seemed to dismiss it being an issue like "oh, you get used to it..." but I must admit I'm still having a hard time believing it...
I recall working on a Pix firewall, which IIRC was a product Cisco acquired from someone else and had something IOS-like, and a true Cisco IOS router more or less simultaneously.

The difference in usability between the two was quite notable, exactly for that reason.
SRECon 2020 postponed due to Coronavirus
X has never supported reliable screen locking. If the screen locker program crashes or is killed because the OS ran out of memory, the X server is unprotected.

It's an unpleasant feeling to come back to an unlocked screen in a shared building.
So true! I built a solution for a legal services outfit a few years ago. First bug they see, they want to sue you. Forget about working with the vendor to refine the solution. They just want to sue you. Never want to work with lawyers again.
camostat mesylate + E-64d

Camostat

CAS: 59721-29-8

Approvals: Japan

$0.10/mg in bulk (2 week lead time), or $1.25/mg in-stock

https://en.wikipedia.org/wiki/Camostat

https://www.adooq.com/camostat-mesylate.html

https://www.medkoo.com/products/11665

----------

E-64d

CAS: 88321-09-9

LD50 in rats: >100000 mg/kg

$12.5/mg in-stock

https://www.sigmaaldrich.com/catalog/product/sigma/e8640

https://www.apexbt.com/e-64d.html

----------

Obviously: untested, unknown dosage and not FDA approved. It would need a little DMSO to dissolve both.
There's no catch. It's called "pooling" and is used, e.g., to keep costs down for early detection of primary HIV infection.
You need to read some Pirsig. Quality is anything but subjective.
The combination of this and a ncursor app framework is much better than GUI application. Unfortunately, I don't find an active great ncursor app framework.
> Badly stretched L2 domains, where the local idea of routing is OSPF

Hahaha… welp. So you’re saying that stretching every “overlay” L2 domain to every hypervisor/physical host with VXLANs and OSPF isn’t maintainable. Color me surprised. I need a drink.
Human DNA is extremely similar to any other human, but coronavirus is not very similar to other contaminants. So you need fewer samples of DNA to determine a match.

Also, even a few percent chance of error in forensic DNA matching is a huge problem. If a virus test is wrong a few percent of the time it's still useful.
I had a boss in a big corp. He couldn't fix the techno-cultural problems but he could and did hold an umbrella over his team. It'd be raining down shit and we were dry.
that workflow has always been my preference. QA can review features in batches, you can schedule releases to minimize impact, and several eyes are on the release to catch possible bugs.
Swedes rebelling against a cashless society (2018)
Most airlines seem to allow rescheduling free of charge at this time? In Asia at least
I'm Vietnamese and I was born and still live in Canada. My body has adapted to the cold quite well and I prefer it over the summer heat. This makes me feel that ancestry is not a part of cold resistance.
Given that the USA is apparently forming a Spaceforce and the long history of astronomical products becoming military products I'm surprised that more companies aren't trying to "go to Mars". Elon can probably tell that a race to be the first to expand heavily into space is coming and that even if he can't sell people on Mars he can sell tourists and the military on the moon.
Yes and no, the SGX flow models a dual-root method where two PKI roots must be trusted for success, and at the same time the SGX is only as safe as the microcode is, which can be overridden at this point. SGX with CPU-signature and Intel-signature can still be faked when you can compromise the CPU and SGX and still run the signing routines.

Edit: I wonder if there is any feasible way one could do this without trusting the CPU at all, but I suppose that completely defeats the point.
Story time: Was once at a military installation in the middle of an experiment. At a critical moment, several security guards barge in and ask to see some paperwork. They had been tipped off to the fact that some of our shipping and receiving and inventory paperwork was out of date (they were absolutely correct, my bad).

I explained that we were in the middle of a very time critical experiment and that afterward we would be happy to subject ourselves to the necessary sanctions; meanwhile could you (guard #1) tell me when the green trace on that o’scope starts wiggling because that’s when you (guard #2) should see a flare across the sky around that hill.

This eventually turned out to be a successful experiment and the security guards had the time of their lives as impromptu laboratory assistants.
> All common colds are a coronavirus and newly discovered ones are novel.

Technically not true - coronaviruses cause 15-30% of common colds. The most common cause of the common cold is rhinovirus (30-80%); coronavirus is next, followed by influenza (10-15%), adenovirus, and then other viruses like RSV. The rest of your comment is fairly likely IMHO, though.
Airbnb may postpone its IPO to 2021 as coronavirus outbreak stems travel
> My employer provides me (and other remote employees) all the equipment needed to work from home. Laptop, Docking Station, Monitors and Keyboards.

Isn't this pretty standard in the U.S?

I've seen employers even offer reimbursement for standing desks, antifatigue-mats, co-working space memberships and home internet.

A top of the line Laptop, Docking Station, Monitors and Keyboard would amount to a few hundred dollars a month even if all of it lasted a year (and most hardware nowdays are pretty reliable for 3 years atleast) - there's no point even discussing this from the POV of an employer that's not a ramen startup off a garage.

The savings from renting a place in any city, the insurance, maintenance and security costs are significant.
What’s SSI and SSDI ?
I tried to improve it with an enlarged blue/white area and overlaying the transparency over that with black text.

https://imgur.com/a/stGip5E
Oh yea, today we can do so much more with less UI, but I'm not into video editing so I'm not sure of what's available. I'm sure there are simpler apps for regular people now.
Not at all.

The effectiveness of a vaccine is related to the effectiveness of the bodies immune response to the virus.

As long as different mutations do not affect the effectiveness of a given immune response provided for by a vaccine, that vaccine will be effective against those mutations.

Mutations can affect many aspects of a disease, and often this means a different level of effectiveness of an immune response, but it really does depend on the specific mutation.

For now, there are no selection pressures on different strains from vaccines; it will be interesting to see what mutations become prevalent once testing of vaccines starts.
The biggest thing with working from home is that you have to actually WORK. For most companies, that means being available and doing “work stuff” during work hours, and that’s not just some stupid rule that incompetent management made up.

Almost all jobs require coordination with other people, and you need to be available to address clients’ needs when they expect you to (i.e. during business hours). You can’t have meetings or other coordination if everyone is on their own schedule.

The only jobs that might not need this are developer jobs where you just need to commit your code at the end of the day. So if your vision of WFH comes from this perspective, you’re in the vast minority of the overall workforce who can operate this way.

Too many people think that WFH means you can set your own hours, watch your kids, have the TV on, go to the gym, run errands, etc. If you have a well established track record, then maybe you can do one of those things in a day, once in a while, but people without the right work ethic will fall off the wagon pretty quickly and ruin it for everyone else.

Especially in a case like COVID-19, people working from home may be stuck with their kids and other family who are also forced to stay home, making it more difficult to establish good habits.
Is Home-Cooked Food Delivery a Step Too Far for the Sharing Economy?
wouldn't 1g of force be the same as they'd be subject to sitting on earth?
More than universal basic income, I would love to also see universal basic services. A guarantee of some sort that the basic income will cover a bundle of basic things such as housing, transport, food, healthcare, utilities.
It's more complicated than that.

https://en.wikipedia.org/wiki/Dodge_v._Ford_Motor_Co.

> Dodge v. Ford Motor Company, 204 Mich. 459, 170 N.W. 668 (Mich. 1919) is a case in which the Michigan Supreme Court held that Henry Ford had to operate the Ford Motor Company in the interests of its shareholders, rather than in a charitable manner for the benefit of his employees or customers. It is often cited as affirming the principle of "shareholder primacy" in corporate America. At the same time, the case affirmed the business judgment rule, leaving Ford an extremely wide latitude about how to run the company.

[...]

> In the 1950s and 1960s, states rejected Dodge repeatedly, in cases including AP Smith Manufacturing Co v. Barlow or Shlensky v. Wrigley. The general legal position today is that the business judgment that directors may exercise is expansive. Management decisions will not be challenged where one can point to any rational link to benefiting the corporation as a whole.

The caveat is important. If a company says, "Customers don't like it when rich people in suits treat <x> like shit. Therefore, if we spend a small amount of money treating <x> better, this will make our customers happy, and they will buy more of our products, recouping the cost and bringing in more profit for our shareholders." Substitute the environment, animals, customers, employees, people in Africa, cancer patients, the children, etc. It doesn't matter if you're completely full of shit, you just have to make the argument.

So while you're correct that companies have a primary requirement to increase profits for their shareholders, in practice, this requirement is incredibly loose, to the point of not actually being a requirement at all.
While this is not exactly a direct answer to your question, these pages may be helpful:

https://shotofprevention.com/2018/03/14/how-flu-strains-are-...

https://www.cdc.gov/flu/about/viruses/change.htm
It uses wasd to move, if that helps.
Hospitals and Healthcare. There is simply too much paper work that goes on.

My father had a bypass surgery last year, and the entire documentation process was a nightmare. It was like reams and reams of paper work, bills, prescriptions. The funny part was they would scan the paper forms and send to each other(blood banks, insurance, clinics etc) for quick response. They might as well have online forms and invoices.
> It feels like bikers increase the risk of a terrible thing happening to both of us.

From the biker's perspective, your driving a car on the road is increasing the risk of something bad happening to both of you.

I'm not disputing that you have no choice but to drive a car on the road, but it's quite possible that the biker is in the same situation.
Wrong again.

You assumed a lot about the parent comment's interpretation. "Disincentivizing work" can be interpreted to mean more likely to study than work. This doesn't mean lazy. Nothing in the parent comment called people lazy for leaving the workforce, just that it disincetivized participating in the workforce.
This article is light on details, but from other reading it seems like there was a flaw in the original test kits.

i.e. they didn't just forget to make kits, they did and they didn't work.
Though I know it's not perfect, free software projects at least give you some ability to discover and hinder government interference. I don't know why you seem more interested/worried about them.
I don't trust the numbers from Italy and China - Italy because they seem to have lost the control completely and there seems to be no proper testing of significant population or tracking of the infected patients, and China because...China.

So far, it seems Korea has the best data over the situation, and is likely the most applicable for countries with proper public health and medical systems.

Per Korea's Ministry of Health and Welfare - http://ncov.mohw.go.kr/upload/viewer/skin/doc.html?fn=158337...

As of today, 150K people tested, 5766 infected, 35 death, 0.6% fatality rate.
Their age distribution looks interesting:

0-30: ~2k infected, and no death.

30-50: ~1.5K infected, 2 death (0.1%)

50-59: 1127 infected, 5 death (0.4%)

60-69: 699 infected, 8 death (1.1%)

70-79: 288 infected, 13 death (4.5%)

80+: 127 infected, 7 death (5.6%)

Their number of infected graph is showing some sign of deceleration - the growth rate seems to be leveling off or slowing down slightly.
> I wound up getting a Japanese kei truck [2]. It was under $4,000 to import, title, etc. It gets 50mpg (4.7 liters/100km) and carries 880 lbs (400kg) in the 4.5x6.5ft bed (1.4x2m). You could use a large-ish garden shed as a garage if you wanted.

This is great information!

I would like to dig in a bit deeper because I need a reliable work truck too.

So in California it's not impossible to find good quality trucks at a great price.

For example: My last truck purchase was a F350 7.3 Turbo Diesel for $1500

Why? Because it was a manual, the diff was busted, body's all dented, seats torn out and the doors did not work as it was run as a jobsite truck and the contractor wanted to get rid of it.

After fixing it up, the challenge became the ongoing registration and insurance fees in California which I had not taken into account.

The DMV in California classifies a F350 as a commercial truck.

As a result, you have to pay a much higher registration and insurance fees than what you would pay for a SUV or minivan.

Because of this, it's financially smarter to just rent trucks from Lowe's/HD/UHaul/CL for whenever I need it unless I'm using it more than 6 months per year - which I don't.

Now this $4k truck is new and welcome news to me, so thank you.

At 6' I'll probably fit a bit tight BUT how much could the registration and insurance fees in California be?

The same as a SUV?

Less?

Please, feel free to contact me please. I would love to continue this discussion
I drive a Mercedes. I like my Mercedes. A Mercedes is not for everyone. A Mercedes is too expensive for a guy who thinks a Ford is sufficient. And some people just prefer Fords.

I run Linux on my Desktop. I like Linux on my Desktop. Before Linux I ran UNIX on my Desktop. I have never used Windows as my day-to-day operating system. Linux is not for everyone. Linux is too nerdy or too elite for a guy who thinks Windows is sufficient. And some people just prefer Windows.

The people who want to will drive a Mercedes. The people who want to will use Linux on their Desktop. They just don't care about what other people are driving or using.
The largest issue with this whole thing is that it seems super broken that like 0.00001% of the population knows about this going up, yet it's going to affect 100% of them in a few years. And still no say in it. I mean we're not even giving other countries a say in it. I hope China decides to shoot them all down when they're over with Covid19.
I'm thinking you may not have actually used RDP over a medium-to-low bandwidth or medium-to-high latency connection. Because RDP is still usable and X is a laggy mess.
Regardless of your anecdotal experience, adaption to cold is certainly genetic to a large extent and the literature seems to support that hypothesis.

https://link.springer.com/article/10.1007/s00421-014-2962-2#...
What?

This has nothing to do with arbitration. Levandowski was sued for IP theft (and faces criminal charges for the same)
Not really. You can use Emacs just for Magit, though, without adopting it for things like text editing, PDF viewing, email, and Tetris.
> Unless someone manually comments about it or your tooling picks it up based on references.

I don't find this to be overly burdensome on the tooling. If the ticket-tracking system can't automate traceability between git commits and tickets, then it isn't well-suited to git-based software development.

We use the following policy:

- A bugfix commit must fix the bug, the whole bug, and nothing but the bug. If that seems impractical for the task at hand, make it practical by breaking up the bug's ticket into smaller elements.

- Bugfix commits always cite the bug tracking system's ticket number.

- The bug tracking system observes the git tree and maintains its own linkage to it.

- When cherry-picking the bugfix to other affected branches, pass the `-x` argument to `git cherry-pick`.

That's it. The (cherry-picked from) comment helps out when just viewing the git history on its own. And the bug tracking system lets you quickly see all of the commits and pull requests that referred to the bug.
Like this one?

https://dns.yandex.com/advanced/

I am sure there are other examples not in cahoots with the Russian government.
You can possibly try to blame China for hiding things up until mid January. But absolutely after that you can’t. At that point the entire world had more than good enough data to see how serious this was and that it was going to become a pandemic. Yet even still now the response in the western world is totally underwhelming for the seriousness of the situation. I’m in Seattle which is heading right towards becoming America’s Wuhan and they still aren’t even cancelling all events or closing all schools and colleges.
Thanks, we'll look into it.
>The ongoing disintegration of the normative human society, loss of extended family structures, and escalating segmentation of what used to be a community to different age and class groups well separated in spacetime is a world-wide disaster with far-reaching ripples.

My theory is that this is the true price of obtaining financial freedom, and hence actual freedom. Community requires compromise (sometimes unfairly more from some than others). But once the glue of economic dependence on one another is removed, what is the force that would make people compromise? Everyone can do their own thing, which is nice, but seems to have some pretty big unforeseen large scale downsides that are slowly revealing themselves.
This is included in fzf itself. See https://github.com/junegunn/fzf/wiki/Configuring-fuzzy-compl...
How many of those users connect via IPFS protocol though? Because I bet overwhelming majority of them use https website, and do not interact with IPFS in any way.
Can anyone guide me how to start with using deep learning with biology I am cs student btw so resources according to that will be helpful
How do you manage to get elected if you're going to take $12k / year away from everyone? Good luck with that.
Facebook is very heavy handed when it comes to these things. I’m talking from my own experience with them. I own a free dynamic dns service, and yes scammer sometimes use it to plant familiar sounding subdomains to cheat users. One such subdomain was related to Facebook. So Facebook didn’t even contact me about it. Instead, they banned my whole domain on FB. If now I try to give people my email address with my domain on Messenger or any FB post, it will get blocked with the message that my domain has malicious content.

That’s what you get when dealing with big companies. I guess they cannot just block namecheap like this, since they are much bigger than my small hobby dynamic dns server. So they are suing in this case. But I’m sure there are plenty of cases like mine where they just block the whole domain or IP range without even contacting the owner. Because they can, and we cannot do anything about it.
Ask HN: Build vs. Buy: What is the true cost of hiring a new software developer?
I am stuck in a build vs. buy decision. I will provide hypothetical numbers in this post to ask my question. Let us assume I am paying $300,000 in licensing fees per year to use a commercial product. I know that I can build that commercial product internally if I hire one more software developer. This developer can build and maintain the internally developed product. Let us assume I can pay this new developer $200,000 annual compensation (base pay + bonus + benefits + perks). Can I assume that I would be then saving $100,000 per year?

For some reason, I think this simple calculation is too naive. Surely it can't be that simple, could it? Perhaps, the cost to the company for hiring this new developer is going to be much more than $200,000? What other hidden monetary costs do I need to take care of before deciding the true effective cost of hiring a new developer?
Wrong wrong wrong.

> You assumed a lot about the parent comment's interpretation. "

No I did not. That the THE primary argument detractors make when they say that UBI disincentivizes work. Read enough on the arguments against UBI and you will realize that for yourself.

Your interpretation indicates that you have not been steeped in debates about UBI, otherwise you would know this already.

Interpreting the parent's remarks, ESPECIALLY when they bring up the existing "detractors" as simply meaning "not working", instead of what is the primary argument the existing detractors make is absolutely disingenuous.
> To use my personal example again, the domain was autostempest.com

So then they claim their company is called Auto Stem Pest in the business of selling automatic pest control devices, and their website had your logo on it "temporarily" because it had been compromised by third party malicious hackers.

Somebody has to decide whether that story is a load of BS. But it's a thing that could realistically have happened, and Namecheap has neither the resources nor the qualifications to stand in judgement.

> Going to court just wasn't an option. For one thing, we couldn't even identify the people behind these sites without first going to court against namecheap. And after all that effort and expense, it's entirely possible they'd registered the domain with fake info and the effort would have been wasted.

The thing is, that's what happens anyway. Most of the people doing this are in countries that just don't care. Having their names generally won't do you any good.

> Even the UDRP option was not cost effective, because nothing would stop the scammers from opening a new fake domain.

Which points to domains being a bad point of attack to go after them. It's like trying to catch cat burglars by maligning department stores that sell gloves. It's just not a useful place to apply pressure.

For fraudsters in a friendly jurisdiction, courts work, because the process is a pain in the butt but at the end of it they go to jail which is a large enough deterrent that it mostly stops them to begin with.

When they're in an antagonistic jurisdiction (which is most common), the law can't help you, because it isn't your law that applies. At that point you're down to technical and market solutions, like the one you found.
Flash was
> The middle class will shoulder the bulk of it

Why is that the assumption?