skysight-inc/HackerNews huggingface dataset:
I am a bit conflicted. According to the comments, one should do very low carb diet to adapt to Ketones as energy. For example, fasting would not be enough for this purpose.
But that implies the need for a ketogenic diet.

Very low carb diets are difficult to do, at least if you are not very rich: Most of them require a lot of meat.
Now, that differs by country. These diets are probably easiest to do in the USA with its huge industrial meat industry.
In other countries, like here in Europe, you'd probably need to be a millionaire to buy that much meat in the first place. I don't know anyone doing this successfully.

But in any case: is it ethical? I doubt that this would be sustainable for everyone. If everyone would eat mostly red meat, we'd probably roast our planet pretty quickly. I don't think free range farming would support 7 billion carnivores, nor would the fish in the sea.

I realize the people doing Low Carb are not necessarily the same who care about sustainability. But if there is such a benefit to Ketogenic diets - for all our sakes - we should think about what happens if everyone wants to do it.

Of course there are options. There are low carb Vegans (e.g. https://www.reddit.com/r/veganketo/), but boy is it a chore to do. Also, I doubt this can be done with anything resembling local and unprocessed products.
Furthermore, a lot of vegan protein products are high in soy. Which is fine really for any amount you'd normally consume. But if you are serious about low carb, you might eat so much that we get into that "questionable" range in terms of recent research.

Perhaps carbs need not be too low. Yeah we can eat a lot of veggies, probably. But it'll be a challenge, I think.
Or not?

Say, you eat meat once a week. How do you do a ketogenic diet without losing your mind in planning etc?
Do users really evaluate like that?

For me, it's pretty obvious that rating is arbitrary and depends on how optimistic/perfectionist/obsessive/etc. the reviewer is and that there is not much difference between 4 or 5 stars.
If possible watching videos on 1.25 or 1.5x speed helps. If the video is live.. then coffee.
They are the only such graphics vendor, but sure. Either way NVIDIA users lose.
This really makes a huge difference, particularly for Congress you can usually got to 3.4 -> 4x speed easily.

You can edit the speed above 2x on YouTube in the web console (I forget specifics, but easily searchable).

I think Andrej Karpathy’s talk during tesla autonomy day, and any talks by John Carmack are the only ones I enjoy at 1x (they talk fast).
The "Record from microphone" option doesn't seem to work in Firefox for some reason; it just spins a loading icon endlessly.
I'd definitely declutter the index page. It's literally too (ooo...) much text. Maybe clarify your value proposition.
If you ask a question at work, and the answer is in the first page of Google's search results, then you risk being ridiculed.

Saying "I looked on DDG" will not help you in this case; it will likely make the ridicule increase.
The problem with wide scale testing is that it makes the CFR incomparable to seasonal flu or previous outbreaks. CFR is by definition deaths/confirmed cases. It's not a measure of infection lethality or mortality rate, even though that's what most of us think it is and what we're most curious about.

For crisis management and planning, you want a CFR that is comparable to something like the seasonal flu or previous outbreaks. "Confirmed" cases of respiratory illnesses are roughly equivalent to the number of people who present to a hospital with severe respiratory symptoms, minus the base rate. We don't go out and run an assay for any person suspected of having the flu, for example, especially not asymptomatic people. If you do that for SARS-CoV-2, the number of "confirmed" cases will sky rocket and the CFR will drop. But that lower CFR can't be meaningfully compared to anything else, and is pretty much useless except as a curiosity.

So it's understandable that the CDC isn't keen on widespread testing; it'll ruin the data, or at least ruin the characteristics of the data most important for crisis management. What matters now from a public health perspective is knowing whether SARS-CoV-2 is circulating. If you know it's circulating in an area, then you should just assume any respiratory illness is a SARS-CoV-2 and quarantine. Test if and only if it becomes severe and you need to know the cause for treatment.[1] You can calculate a more accurate and consistent CFR later by subtracting the base rate of presented respiratory infections from the outbreak rate.

Identifying a local outbreak does request testing, but the major problem there was a temporary problem with getting assay kits out. But going forward, it doesn't help to test people who aren't presenting with severe symptoms. At least, it doesn't help from an epidemiological perspective.

[1] However, SARS-CoV-2 causes primary viral pneumonia. By contrast, severe symptoms from seasonal flu are caused by secondary, bacterial pneumonia. There's not much that can be done for the former; for the latter you can prescribe antibiotics. So for severe cases it might just make sense to prescribe antibiotics, which would be benign for the viral infection (COVID-19) and even possibly a prophylactic for secondary bacterial pneumonia. In other words, in terms of treating a severely ill patient with a clear case of pneumonia, positive or negative COVID-19 identification might not provide any benefit.
Hello Amro, thanks for checking it out whenever you do, and the comment, much appreciated. Cheers, Ace.
Have any of the systems you've designed ever been used for something they weren't originally meant for? Will they ever? Do you have any guarantees of that?

You can say that the systems that you're building are not being used in a dystopic fashion, but in doing so you're ignoring the fact that you're still building scaffolding for the rest of the industry.
Rick Santelli Calls for Infecting Global Population with Coronavirus
No, you probably suffered from nutrient deficiencies, symptoms that went away once you diversified.

A total guess of what happened to you, but what's not a guess is about the adaptation taking months and being about anything more than dehydration or nutrient deficiency being total bullshit.
Case in point: Julian Assange and Snowden
Full title:

'This Is Your Brain on Capitalism': CNBC Market Analyst Rick Santelli Calls for Infecting Global Population With Coronavirus to Help Wall Street | "The projected death of 11 million Americans would be a fair price to pay for better long term stock growth, says a capitalist extremist."
Thanks for sharing your perspective. I can see how per-user pricing doesn't scale well for you.

> What questions do you have?
We're curious what specific flows you were interested in migrating over? Who performs this work today? How does it work end-to-end? What tools do you use to track the work? If you prefer to message me privately, my email address is nick <at> flowdash <dot> com.
ideas have people :)
The data page seems to be more up to date than the map.

https://ncov2019.live/data
I miss my up to date access. Tangential -- I do not think people realize a resource like UpToDate exists. Well written up to date summaries of various medical topics based on the latest research. Were something like this to be publicly accessible it would do wonders. If anyone is working on or wants to work on this type of problem please let me know, I'd love to help out (programmer, former MD).
Lockdown, the App That Reveals Who’s Tracking You on Your iPhone
Show HN: linkhere – show sites saved from mobile in new tabs
Hey HN,

I was tired of emailing myself websites from my mobile device that I wanted to look at later on a bigger screen, so I created linkhere last weekend. It's a simple browser extension that unobtrusively shows websites saved from your mobile device in new tabs on Firefox and Chrome, while being completely self-hosted and private.

Repo with instructions and demo GIF: https://github.com/link-here/extension

Let me know in the comments / open a new issue on what needs to be documented better.
We called him out on it, he sent a new version and we executed. On the big contract he tried several other small variants on this (going back and post-hoc altering wording that had been agreed, delaying things for no reason, just generally being an incredible pain in the ass to deal with in a million small ways) until we got a press release from the CEO of his (global) company saying how happy they were to work with us and his demeanor instantly changed and he became super-constructive and efficient.

In spite of everything everyone on this thread thinks/says, it definitely wasn't an error. I spoke to another third-party vendor (over a beer) who were going through purchasing at the same time as us and he was doing the exact same thing with them.
Super important question, first thing that came to mind. How would you even test it for efficacy? Just look for ice building up and say 'welp, time for refinish?'
I feel a better system is just thumbs up/thumbs down. Either it was satisfactory, or it wasn't.

Basically the same as our current 5 star/1 star dichotomy but it makes things more clear to people who are tempted to give 4 stars.
Is this because runtimes optimize for the CPU stepping during startup? How many people actually rely on moving workloads around as live processes without restarting? I thought the industry had settled on "cattle, not pets" and letting instances appear and die as long as a quorum is maintained.
NPR and member stations working together to alleviate 'news deserts'
They could circumvent that problem by replacing the five stars with an up/down system -- since that's the way it's interpreted anyway. I don't think most users are capable of giving more nuanced reviews anyway. If they can, it would be better expressed in words than as numbers.

If I have a stay that's genuinely superior, I'll write an enthusiastic review. Other than that, "it was fine" or "don't come here" is really all I need to say.
Programmers over 45 or so make up a pretty small fraction of the total, so arguably excluding them simply doesn't matter that much. And the ugly secret of software development is that almost all of it doesn't matter either, thus greatly limiting the true need for the expertise that older programmers bring.

I'm old. My advice to those who are aging: Accept that positions involving stupid software tricks for huge bucks will dry up for you. Instead, look for work that's truly useful. It doesn't pay much, which means there's a scarcity of candidates, which means that they tend to value skill over youth.

And it's your chance to plant those trees that you'll never sit under.
> There was no authentication at all on the email there. I did report that, hopefully they fixed it fast.

I bet there was some token in the URL, and that URL with the token was sent as the referer, and then when you clicked the link, you also got the authentication token since it was in the URL.
Agreed. I guess what I'm suggesting is a socialization of the act of card creation & curation so the group creates/uses them.
Freeablo (Open source Diablo 1 rewrite), first new version in 4 years
> From the racists on food stamps and welfare who want it cut and then are /shocked/ when they lose it after their canidates are elected. Everyone with a rent controlled apartment who opposes building more housing while blaming billionares simutaniously for gentrification jobs and lack of jobs causing the area to go to hell. Those complaints about traffic while opposing public transit expansion, or the sorry state of roads while angrily rejecting gas taxes to fund it.

Many of these cases are examples of tragedies of the commons, where people "rationally" advocate for their individual maximum utility, while suffering the costs when the commons is overwhelmed by the everyone doing the same.
Twitter's inherent encouragement of very curt, non nuanced, and the most attention gathering tweets as possible is bad enough as it is. I can only imagine this being far worse.

The medium is the message and the medium is pretty dumb as it is.
That seems impossible to measure, it'll be confounded by the current slowdown in the markets which seems likely to make fundraising harder regardless of whether meetings are in-person or not.
I was thinking Tony Stark. "How did you solve the icing problem?"
The OP article is common knowledge and is a copy of a copy of a copy. Your first link, on the other hand, is the perfect recipe for my Friday afternoon. Cheers!
Thanks, I've just changed it. It's definitely looking better. I tried border effects but I think they're too much for my (almost nonexistent) design skills.
The paper reads like an index into a number of related research fields. One running example, very concise explanations, maaaany references.
Know If You Can Lose Your Job If Quarantined During the Coronavirus Outbreak
I feel like coffee would make the slow talking seem even worse, maybe beer?
I would say it leans HEAVILY towards luck. Given their background and abilities, they certainly would have done well regardless, we have to remember that "done well" can be measured in the hundreds of thousands of dollars. To increase that by another 4 orders of magnitude isn't going to be simply due to being capable.
> only good if everyone understands the problem and solution space equally

That's a goal of pairing up. Together you'll get it better than you would have separately, if for no other reason than the one person who already knows it has to be able to explain it. And as a bonus, now that knowledge belongs to two people instead of being siloed with one of them.
Good catch, that was not on purpose.
I'm sure they tailor it based on the amenities listed. They won't ask you if the pool was clean if the host doesn't advertise having a pool. They probably also tailor it based on historical complaints. If a guest has complained about a particular home being dirty, then future guests are asked more often about cleanliness.
Having used Kotlin for a while now, I find it really unfortunate that `const` wasn't `val` for the sole reason that it's 5 characters instead of 3. `val` would have matched nice with `let`, and my multi-variable declaration statements could have had a nice 4-space indentation while still being all aligned.

I know it can be confused with `var`, but no one should ever use that now that `let` exists.

One of these days I'll write my own little language that compiles to TypeScript or something and fix that :)
I wonder how changing the rating system in cases like these from a five star scale to a thumbs up/down system would affect user behavior and system usefulness. It seems like ebay, uber, airbnb, etc all suffer from the same "anything less than 5 stars is effectively negative" issue.
Probably a (mono-axial) spectrometer: the muti-axial devices are usually used for glossy varnishes or metallic finishes featuring either aluminium or mica inclusions. Multi-axial spectrometers are typically an order of magnitude more expensive and are usually limited to industrial (typically automotive) applications.
G2 and Capterra et al are gate-keeping cancer.

Change my view.
https://pqrs.org/osx/karabiner/json.html if you want to know a bit more about them
This kinda sucks, but as someone who was in China for Chinese New Year (when all large gatherings were banned), I understand the reasoning.

That being said, I think we at Wanderlog (W19) would've needed much longer to raise if not for a chance in person meeting at Demo Day.

We were encouraged to cold-pitch investors in person in the halls during breaks at Demo Day. For one of those pitches, I found an awesome investor who'd heard of us through a friend. While he'd thought there was a gap in travel planning tools before, this chance encounter gave me the chance to sell the company a lot more than we got from the super-brief Demo Day presentation. We had a handshake deal 3 days after that.

We wrote more about the lead-up to experience in our blog at https://wanderlog.com and my conclusion is: it's harder to forge that quick trust and connection anywhere other than in person.

That being said, I do realize we were very lucky. This change could be good for some companies and worse for others, as it rewards solid businesses more than charismatic pitchers. I'm looking forward to seeing the Demo Day pitches for this batch!
I like that - author is clearly clued up

I find it quite fascinating how this concept of moving into management is different from finance. There is still a lot of emphasis on actual doing here. Which makes sense in the "technical lead" sense of the title

e.g. It would never have occurred to me to include pair programming as part of management

Article also seems to imply a fairly flat organization. i.e. managing very few people / grades. By the time our guys get designated manager they've got 20 people reporting to them & have realistically been "managing" for years already.
i'm going to guess that giving his name out in a public forum combined with the contextual knowledge we now have will make it very obvious who OP is. and then its possible for that asshole investor to further sue him for slander or whatever else
Alan Watts discussed at length how modern science mainly focused on the study of things through the analysis of their inner properties, mechanisms, components, etc. Thing is, nothing actually exists in a void: what something is only tells us half of the story because in what context it exists matters as much.

Everything constantly interacts with its environment in a complex web of interactions. As apples grow from the tree, the Earth grows people. No environment, no organism. One always goes with the other.

So, back to engineering particular bacteria, it's no surprise they would only survive in the long term if their environment somehow "allows" it: the engineered bacteria eventually needs to find a viable place in its ecosystem where it fits. So while trying to grow a single new bacteria consistently failed, introducing multiple ones adds the fact they're now coming with their own mini-ecosystem to support them, apparently improving their odds to find their own place in the environment.
Better: Always use the python2 and python3 commands; never python.

Same with pip, etc.
GPUs would still be faster than CPUs. You describe them as high-latency but their memory latency is comparable to CPUs. That's why ethash mining or equihash mining (workloads bottlenecked by short ≤32-byte random memory reads) is still faster on GPUs than on CPUs. Also see https://news.ycombinator.com/item?id=22505029
If you predict a recession every year you will eventually be right
> cattle, not pets

People running VMWare don't even consider that.

Most people have that as a goal which they aren't achieving (and that's fine).

I would doubt there's any company in existence actually attaining that goal.
You're confusing leaders with policies.

In a pseudo-democracy policy priorities are defined exclusively by the oligarchy, and the required opinions are sold to voters through media channels directed by think tanks and PR outfits.

Voters are persuaded they have a choice over personalities and superficial issues, but never over national policy.

If a politician appears to threaten the cosy consensus, the media wurlitzer goes into overdrive to smear them, talk them down, and persuade voters that they're "extremist", "not electable", and other stock tropes.

So - it doesn't matter if leaders are voted out if key policy goals never change. And as a rule they either don't, or they change in ways that benefit the oligarchs, not the majority of the population.
first off drugs that influence the components of the RAS are not childs play, so yes consult your doctor[s] rather than experimenting with dosages.

This is only just starting to see clinical trials, meaning the people involved are under direct physician supervision.

regarding ACE2:

this increased production of ACE2 is an indirect effect of ACE2 disruption.

you have to be careful with these sorts of experiments.
when you block angiotensin II receptors that means there is a reduction of signal for angiotensin II being present.

This angiotensin that would ordinarily be interacting with the ATreceptors is now available for ACE2 to operate upon.

the summary here is that increased enzymatic product doesnt mean the enzyme has been "turbocharged" . If there is an increased ratio of reactants to products this will cause increased concentration of products in total but does not change the intrinsic rate at which the enzyme actually operates.

This looks like a case of substrate concentration dependent equilibrium driving reaction rate.
The greatest potential of this is building a custom CPU that has a desired set of functions built in. If you do a lot of addition, add more adders. You choose the balance of fixed or floating point, or you could put in decimal floating point operations, etc.

This would be fun to implement on an FPGA since you could add and remove operations at will.

A very intelligent toolchain could synthesize alternative CPUs based on the bottlenecks that some particular software finds; that codesign could make very good parts.
I love carbs.
Fair observation. I think, though, that the culture and the PP were closely intertwined with the two feeding each other.
It's the same thing with Uber and Lyft. Dropping below 5 stars can result in termination.
>>99.9999999...% of children of
No, as reviews often mention specific details of the location - even if those details are mostly positive.
The main thing I still use g! for is "wolfram lite".

I just tried "3 watts * 4 hours" on Google, it gave me the answer in joules (which, I think situationally watt-hours would be the better unit, but...) and DDG gave me a top hit of a site that could do the conversion for me.
Thanks for sharing this, Ace!
Space lettuce: Nutritious crops would assist long-distance space missions
It's not users, it's the platform itself. AirBnB and other companies like Uber and Lyft will significantly deprioritize you if your average rating isn't very close to 5 stars. Rating your Uber driver 3 stars can significantly affect how many fares they're offered and therefore how much money they can make.
This is really cool and I think you're doing more due diligence than any HN user I've ever seen. The confounding variable is that you lost a lot of weight, of course, and I think many people who lose weight will be healthier at least in the short term. A question I've had in my head for a while is whether someone who has to stay on a ketogenic diet to be a healthy weight has "healed" or has just masked the underlying issue.

Would be interested to see your thyroid numbers as you continue on your ketogenic/fasting diet. "In range" does not necessarily mean optimal, and in general I'd be worried about T3 uptake going from 33 to 23 even though both are in range. The liver converts T4 to T3 in response to glucose availability -- this happens in many tissues, but they all depend on a liver enzyme, and most of the conversion occurs in the liver.

Low CO2 is a sign of kidney stress and acidosis. I also believe it's a marker of a low metabolic rate, much like thyroid.

Prolactin is a longer discussion I don't want to get into here (much like you on your LDL-C :)) but I'll definitely be following your posts as I think you're doing your part and have done more research than I have so maybe I'll comment on your blog sometime. Put very briefly I believe high prolactin in men can be a sign of chronic stress and calcium deficiency. It's been linked to gynecomastia, for example, which makes a lot of sense. In general I like to look for tests that show whether something's wrong, rather than what's specifically wrong. Someone might have alright D but still have issues properly metabolizing calcium.
Same question by same user recently. I don't see why different answers are not expected. https://news.ycombinator.com/item?id=22425811
As far as I’m aware all Linux users are out of luck. Buying a cheap used android phone for BankID is probably the easiest solution.