skysight-inc/HackerNews huggingface dataset:
Just to be clarify, B cells undergo somatic hypermutation while undergoing expansion after antigen recognition. On re-exposure, memory cells will be available to identify existing antigens and re-expand the B cells involved with attacking the viral particles.
> If you're interested in losing weight, find a strategy for eating less (by playing with what you eat or with meal timing).

I'd just like to chime in and echo this sentiment. I myself have lost and kept off between 2 and 3 times what parent has and it was also no thanks to keto, or any fad-diet bullshit.

There's no magic to losing weight. Consume less, expend more, weight loss ensues. Yes, it is that simple. No, that doesn't mean it is easy. There are many different paths but they all lead to the same place.
Quite meticulous: what are you using these spreadsheets for?
OKCupid is making a lot of noise these days about requiring a phone number, right after Facebook themselves had a massive breach (267+ million numbers):

https://www.forbes.com/sites/johnbbrandon/2019/12/19/267-mil...

Either it's a bizdev scam that they're all trying to get in on, or they're clueless. I lean toward the latter but expect it to be the former. Surely they can raise ad rates with the extra PII, I'm guessing?
Record from mic works for me. Listening to https://www.youtube.com/watch?v=FATTzbm78cc in one window with mic recording does the expected at the end of the song — https://www.magneticmag.com/2012/08/the-aphex-face-visualizi...
Fuzzing Error Handling Code Using Context-Sensitive Software Fault Injection [pdf]
Ketosis is a normal supplemental metabolic state that the body enters in between meals to various degrees. There's no hard black/white macro requirement.
LA's Fastest Growing Startups (Pitchbook/Dot.la)
Interesting... I wonder how the synchronous -> asynchronous switch could impact the amount of attention given to presentations for non-flashy companies. In the in-person model, investors sit through the whole presentation. In this one, they could turn them off and switch to another half-way through, whereas maybe if they had watched it all they would have seen some otherwise compelling information. (in theory)
They need to work on making faster cores instead of just throwing a ton of cores at the problem. In the datacenter, we commonly have to pay per-core license costs for certain vendor software. I'm not going to pay 7 figures to grow our Oracle license for example by switching to AMD when we can get Intel CPUs with faster, fewer cores.
I assume they are able to target these users with advertisements (by paying Facebook money..)
Media attention was similarly short-lived regarding the closing of the Russian consulate in San Francisco and the Russian compound in Maryland.

Yes, Israel usually gets a pass on espionage, and Russian election interference is a years-long story. But in any particular incident it's hard to tell whether the public is disinterested in the incident or disinterested in the adversary. Plus, to be fair, reports of actual Russian incidents are fairly common. I mean, they've literally built a niche industry for social media hacking. Reporting on it is easy; you don't need to wait for intelligence leaks. And they publicly gloat about their strategy and tactics. By contrast, Israel is usually far more discrete[1] and publicly identified incidents are few and far between.

[1] Operationally and politically. They certainly don't gloat. They stick to a very strict recitation: "Israel does not spy against the United States."
C++ Lvalue Reference and Rvalue Reference
Are you on a path to get 5-10x users?
Have you tried amazon s3? What is your use case? Can you elaborate?
edit:Grammar
Unfortunately this was 15 years ago so the details are lost to time. The memory I have is more about watching him demonstrate in-person how to hold a baby, how much crying to expect, what fever behavior looks like, etc.

I'm also not a clinician or a parent so I'm going to refrain from giving out specific advice, even if I witnessed it first hand. I'll ask him next time I see him and if he has something written I'll update this comment.
Christchurch mosque shootings: Facebook attempt to mollify families falls flat
Had a doctor tell me ketosis was very dangerous (she was confusing it with ketoacidosis). I couldn't help but completely stop listening to her after that.
I subscribe to this application, and I love it. I was not one of the first 100 to experience any of these difficulties, and the one bug I did experience was fixed by Jen two days after I pointed it out. In the mean time, Mint still has not deleted my account two months after I requested it...
WA is great for certain more complex mathematical or informational queries but usually requires me to dig around to find syntax since the NLP isn't as fluid as I'd like it to be.

I basically view it as a slightly more friendly/natural than traditional Mathematica interface.
This is what people designing multiplayer games try to do - keep meta as interesting as possibly by making as many strategies viable as possible.

That's why Starcraft was the start of mass-scale esport. Because it had 3 races to choose from instead of just 2 as previous real-time strategy games used to have, and because the ambition was to keep them balanced.

It meant even if matchups weren't perfectly balanced (they never are) - it was possible to make each faction(race) viable over many matches - because third of the time you play vs same faction, and third of the time you play vs faction you're favoured against.

It doesn't have to be just 3, either, there's often several styles within each multiplayer race/faction - for example usually early-game strategies win vs late-game, late-game beats mid-game, and mid-game beats early-game. But there are special cases and close calls between particular ones of course.

BTW for people with experience in multiplayer games who want to laugh a little and look at biology from a different angle I recommend TierZoo youtube channel https://www.youtube.com/channel/UCHsRtomD4twRf5WVHHk-cMw

It's mostly a parody based on the premise that Earth is a multiplayer game, the nature is balance-patching every few million years, and the channel is a guide for the game :) The analogies are sometimes surprisingly close.
Presumably middle east or north/eastern africa.

Then again I'm sure there are plenty of SV hipster types who might be big on it. "forget microdosing, khat is the new path to rockstar programming flow states"
My current impression is that AMD is not the best option for ML but is getting better over time. So YMMV. That said, I do not use my local machine for ML (and don’t do ML in any serious capacity.)
Yes, but it comes with a cough of coronavirus.
On the pricing page, the Growth box shows a checkmark for "Unlimited labels" but right below in the "Choose the right plan for you", the Growth plan says the number of labels is 10,000,000.
What should replace third party cookies?
Can You Fry an Egg on a Hot Computer CPU? This YouTuber Proves You Can
When trying to discern the details between trim levels, I've found looking for actual PDF brochures for that model year is the best route (something like this: https://cdn.dealereprocess.org/cdn/brochures/mazda/2020-mazd...). Nearly every vehicle brochure I've found has a table outlining what is included with different packages and trim levels.
You are right. There are always multiple sides and stories for the same situation.

It is perfectly possible that it could be that way, and I wish it was that way because then it would only be a money issue, which could (in theory) be rationally resolved.

Things that somehow contradict that, is how unwilling to resolve the issue the investor has been. The company was profitable at the time he ended his contract and called the note. At that time he said he didn't care about his note, that he'd just write it off as a loss and he'd get 50% back in taxes. He could also have gotten his money back by taking a payment plan. Additionally we offered up the assets as payment so we could avoid bankruptcy, but he refused. Then he abandoned the assets after acquiring them in bankruptcy.

To me it doesn't make any sense, but I hope you are right, that this is only about his money and that we can somehow reach an agreement that puts a definitive end to this mess.
Block compilation – “Fresh” in SBCL 2.0.2
Nope, but I understand your question because there are not so many Aussies in the Yukon (though more than I was expecting...)
Out of curiosity have you read benchmarks recently on Rome? Per-core performance is quite competitive now (unlike in the recent past).
I would recommend hiding your gender. You'd be surprised at how awful women can be to each other. The only people I see activity holding back women is other women. I just don't understand it.
Any object storage system (S3, Backblaze B2, Azure Blob, GCP) should be able to handle those file sizes with proper chunking into smaller parts (limit details below per object store).

S3: https://docs.aws.amazon.com/AmazonS3/latest/dev/mpuoverview.... (Max object size: 5TB, Max single multipart size: 5GB)

Backblaze B2: https://www.backblaze.com/b2/docs/large_files.html (Max file size: 10TB, Max single object size: 5GB)

Azure: https://docs.microsoft.com/en-us/rest/api/storageservices/un... (Max file size: 4.75 TB, Max single block size: 100MB)

Google: https://cloud.google.com/storage/quotas (Max file size: 5TB, doesn't appear there is a lower limit for objects to be composed into a single object, docs could be better in this regard)

@khc: Terminology updated to be more clear for S3
>"see your results in Events Manager and Facebook ads reporting."

businesses want to see if their ads are working. by uploading their visitor records, they can get reports of how many people who saw their ads visited the restaurant.
Better placement in search and greater reach with posts, I'm sure. That's pretty much all FB can use to trade without displaying a currency sign anywhere.
Sounds like eBay, buyers can't get anything other than a positive review. You can write whatever you'd like in that review but no one reads them.
The concentration of power, in this case, refers to political power not market(economic) power. If you think about it carefully, economic power often is very weak and vulnerable as they often derive them from consumers which means they can only maintain it by giving consumers what they want. People like Bezos, Bill Gates are far less powerful than say, Putin, Erdogan, Xi, etc.

As an example, how far did Bloomberg's billions take him in the democratic nomination?
Civil lawsuits come down to just one thing in this country: MONEY.

Not the law, not what is right or who has been virtuous. Just money. Or more specifically: who has the money.

If you are poor and you sue someone who is rich, they control that outcome. If you are rich and you sue someone who is poor, they (by default) control that outcome; there's nothing there. If you are both poor, a judge will often decide based who looks and sounds the less poor. If you are both rich, then (the equivalent of) actuaries decide the outcome.

Criminal lawsuits are similar. I do not care how much you fuck up in this country; The amount of time you spend in jail will be inversely proportional to the amount of money you can spend to fight it.
I have often worked from remote. Our work laptops have a full tunnel VPN. I use the same tools at home that I use at work. Everything works exactly the same way for me. From what I have seen, this is rarely a technical challenge. Each team need to have a culture that supports working from remote and that depends heavily on management training and ethics. This also assumes a level of professionalism on the part of the employees.

For me personally, I can get much more done working remote as I have less distractions.
I mean you can slather just about anything in melted butter, salt and pepper, and put it on a toasted buttered bun, and find it tastes pretty good
Or the panic could be a great boost to the ocean ecosystems. Just like WWII was because fishing boats were afraid to leave ports lest they get caught in cross fire.
Two other things I should add:

I use noise-canceling headphones (inexpensive from Taotronics) and the DFX plugin [1] for audio clarity. The plugin has a Dialog Boost setting intended for transcription. It goes a long way to improve muddy audio.

[1] https://www.fxsound.com/uses/transcription
I think he was following the thread just fine. (And I didn't downvote you).
I wish I could permanently remove pinterest from my version of the internet - it's literally spam at this point that never contains the content I'm looking for and adds no value while polluting search results.
It's not that common shocks to an economy to have a permanent effect. Businesses and investors understand that the event will be temporary, some businesses may shut down during the event but once the event ends, the pent-up demand it generates and allow spending on recovery, tends to more than compensate.

That said, the economy was an extremely fragile condition before all this began so this might be an exception.
I just googled DDG and nowhere on the front page did I see DuckDuckGo. Interesting, although not too surprising.
I’ve predicted twelve of the last three recessions!
You've made the mistake of assuming that any significant fraction of the population even cares.

Whether or not anyone has this information is totally irrelevant to me, and I'd imagine this is true of upwards of 95% of the population. And hey, if it leads to restaurants bringing in more people, it'll lead to more restaurants I like staying open instead of going under...
> The UK and Canada have approved Huawei to supply critical networks,

If you're referring to 5G, Huawei has yet to be given a green light in Canada. Perhaps you're referring to some other infrastructure, however.
Unlikely... the bulk of their revenue is based on ad payments, either on search or on individual sites. I'd guess it's probably 70:30 roughly, since you're probably almost as likely to search on google first and click a couple results. So they'd probably take a 30% hit just from loss of ads. Behavioral information from starting from a google search should also not be under-estimated which is probably where they get a lot of their behavioral data from to begin with (you searched for X, went to Y for Z seconds, etc).

adsense, analytics and search are all pillars of their core income sources, if you take one out, the value is seriously impacted overall.
This next recession will be very ugly. I hope everyone on here is prepared. Last time the dollar was a safe haven asset, so those that saved were ok. We will have stagflation and the price of the dollar will collapse.
I've been using Sia for about three months to backup some personal files. Nothing crazy, but it seems to work well.

I'm looking forward to seeing this project mature as well as have some more layers build on top of it moving forward. I really wish the client offered synchronization or access across multiple devices. For now you have to try third party layers on top of Sia to accomplish this.
Is it not expected that when you pay money for a service then the performance should be good? Good service should be the default. If the service is outstanding then that is when we should start giving a bonus.

US tipping etiquette has nothing to do with good service and all to do with propping up underpaid staff.
Not that surprising.

There is a reason why EU made the GDPR. Its not like it was a law meant to solve a purely theoretical problem
Making the broth for lobster fra diavolo for example
"MP" for lobsters means "we are gonna soak you".

Places that aren't going to soak you will put a price and that price won't be insane. Like places in Maine that say

"Surf and Turf - $19"

"Add a lobster - $9"

"Twins - $14"
The issue is the "generally considered harmful." High-fat low-carb diets tend to improve triglyceride profiles. Dietary cholesterol is not the same thing as blood cholesterol levels.

Anecdotally, my father and I discovered separately, in bloodwork unrelated to our individual diets, that a HFLC diet significantly decreased LDL and increased HDL.
No but I'll certainly pass the word along. I handle the network and wasn't directly responsible for evaluating AMD. I just heard the reasons why it didn't work and saw the not-so-impressive benchmarks when looking at single core performance. This was 2-3 years ago.
I agree with the "tell the story as if you were telling it over beers at a pub" part but please don't make your page 9Mb like in the first example ;)
> everyone I know that has these replaces them well under that time frame.

Survival bias. Nobody is thinking about the bulb they haven't had to change in 20 years.
I've always thought a "threat" of leaving is a meaningless concept. It's either a bluff or it isn't. Most straightforward way to handle it is to find another offer that you will legitimately take if you don't get a sufficient salary bump, and communicate that there aren't any hard feelings, you just need what the new employer will pay you. If your manager refuses, you move, and if he bumps your salary or counteroffers, you can reassess. This is really the only way to handle it if you want to keep things simple. Or, you can bluff.
My experience with Scala is that `var` and `val` fortunately look very different in source code. `var` jumps right out at me, perhaps because the shape of the word is so different.
Or a good place that will overnight some to you.
They just taste sweeter. Plus a 1 pound California lobster has more edible meat than a 1 pound Maine lobster, despite the huge claws of the Maine lobster. It's all tail meat. Plus the "face meat" (meat underneath the giant spiny antennas) is an amazing and distinct flavor.

It's a smaller fishery too, they aren't that common north of Point Conception.
Interesting. I've never had a problem with this or noticed it. I couldn't ever give up coffee though :)))
because everyone and their mom is on it so its a readymade community.
It is possible, and I'm hoping that's the case (that it is not a personal issue).

Replied to another comment of yours with more detail on why it looks like a weird situation.

To add a bit more: our investors, the lawyers that we've worked with so far and even the bankruptcy trustee's team, have all been surprised by the way this guy has been handling the situation and seem to agree that it doesn't make sense to proceed that way in terms of getting a return on his money.
Oof. I was surprised for a second that Babel would simply put "var" in there instead, when it expressly doesn't do the same thing. But then I realized that emulating block scope without let would mean wrapping all blocks in anonymous functions, which would carry significant overhead.

Gross.
Use https://github.com/igrigorik/videospeed instead.
That’s a great essay, alright – and still stands the test of time. I remember Rick Moen’s contributions to mailing lists in the early 2000s being insightful and informative (for me).

When I first started using GNU/Linux in 1999 (Red Hat 6), I found it confusing to understand what all the fuss was about with libc/glibc and egcs/gcc. I think the differences had been resolved by that stage but all the related documentation referred to the split which made learning this strange new system very confusing (at the time, I knew what a compiler did but I didn’t know about anything about architectures other than x86 and I didn’t know why a C library was so important).

Rick includes a reference to the Emacs split of the early 90s. Jamie Zawinski’s reflection on this fork is quite interesting: https://anonym.to/?https://www.jwz.org/doc/lemacs.html (using the anoymiser as Jamie doesn't seem to like news.ycombinator.com as a referer).
It absolutely is.
FB and google aside - why does something like signal need section 230 protections to operate ?
My CTO asks me this everyday. I guess the answer is they marketed it well as a comprehensive tool for teams/companies. Everyone knows about it. A lot of ppl use it. It has integrations built in. No need to install anything. Does the job.

There are things we don't like about it but it does the job well enough that the opportunity cost of trying to replace it too high for us at the moment. So we keep going with it.
> My claim is that capitalism accumulates wealth with a small percentage of the population who then end up running the country as an oligarchy. Your iPhone example does not in any way contradict that.

Please do not change the subject, we were discussing zero sum game.

> No, I've described how capitalism subverts the government to the interests of the rich oligarchy produced via the system of capitalism.

Capitalism requires a separation of economy and state. What you're describing is Cronyism:

> Cronyism is the practice of partiality in awarding jobs and other advantages to friends or trusted colleagues, especially in politics and between politicians and supportive organizations.[0]

If capitalism is polluted with cronyism, you get Crony Capitalism:

> Crony capitalism is an economic system in which businesses thrive not as a result of risk, but rather as a return on money amassed through a nexus between a business class and the political class.[1]

> That's the whole point, cheating, lying, and stealing are all effective means of being competitive under capitalism. Since making profit is the sole metric for success, these behaviors are inherently encouraged by the system.

Except for the part where you spend jail time for fraud or theft.

> False, the study clearly explains its methodology and the definition for capitalist countries.

> The discussion is whether capitalism improves quality of life, and the study clearly shows that it's false across the board.

Look, the point here is not terminology. If you think Ghana is capitalist (as the paper claims), I can see why you won't like that system. Please consider, for the sake of this discussion, my definition of capitalism.

> Meanwhile, I fundamentally disagree with your definition of freedom. A system that forces people to sell vast majority of their lives simply in order to survive is a form of slavery. It takes an incredibly dim mind to primarily conceive of freedom in terms of consumerism.

That's the beauty of Capitalism. You're free. If you don't like the way of life, you go with people who think the same way, and you build yourselves a _voluntary_ communist heaven. No one will stop you, as in capitalism, all the state does is protect you from violence (which I guess is a role we agree on).

[0] https://en.wikipedia.org/wiki/Cronyism

[1] https://en.wikipedia.org/wiki/Crony_capitalism
If they don't make enough in tips to reach minimum wage, the employer still needs to close that gap. It's not as exploitative as we're led to believe, or at least no more so than working a minimum wage job is normally.
The fundamental problem is that as soon as a metric is used for financial incentives, it becomes useless as a metric.
1- Make the best decision for you in terms of pricing and conversion target (just go even or aiming to make some money?); 2- Send all your users a very clear message (no explanations, just the new terms and conditions) and allow a 30 days period to convert or recede; 3- On day 31, just switch.
On smaller viewports the footer has a left and right margin of 15px. I would drop that and always make the footer fill 100% of the width.
What actually is a 4to6 gateway? For example, how would an IPv4 client connect to a 128-bit address like 2606:4700:20::6819:6c0d?
There are studies looking at this question.