skysight-inc/HackerNews huggingface dataset:
if you head down to page 4 of the paper there is where you will find references to background literature cited regarding
"neuroinvasive potential"

[1] Glass WG, Subbarao K, Murphy B, Murphy PM. Mechanisms of host defense
following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary
infection of mice. J Immunol 2004;173:4030-4039.

https://doi.org/10.4049/jimmunol.173.6.4030

[11] Li, Y.-C., Bai, W.-Z., Hirano, N., Hayashida, T., Taniguchi, T., Sugita, Y., … Hashikawa, T. (2012). Neurotropic virus tracing suggests a membranous-coating-mediated mechanism for transsynaptic communication.

https://doi.org/10.1002/cne.23171
I use more than one zone because I run TCP services which need low latency. I'll probably just switch to Digital Ocean.
not long ago ... https://boingboing.net/2017/10/28/warning-taken-as-suggestio...
Or you could donate them to your local hospital since there is a shortage. I’m not sure they would take them, but it’s worth considering.
In WWII it was the domestic auto industry that converted over to building tanks. However today most of the domestic auto manufacturing is for foreign companies like Toyota, while our domestic companies largely manufacture overseas or in Mexico now.

It would be amazing if WWIII broke out and we had to call on Tesla to manufacture tanks.
Yes. It is worse than a regular flu. But, if you look at statistics from S. Korea, the only country with a substantial infection and trust worthy numbers (as in they test heavily), the death rate is around 0.6% overall. So not the end of the world, but nothing to be complacent about either.
If the White house will get out of the way and let the system work, we may still have time to mitigate the worst here in the USA. But of course, we don't even want to cancel SXSW. What more needs to be said? <insert Darwin thumbs up gif >

Addition: No, I "trust" the reported numbers from Italy. I think they are missing a lot of mild cases that are not being reported or tested. When I checked a few days ago, it looked like of the tests that South Korea ran, only 5% or so were positive. So, their infected numbers are probably more accurate. The death rate may still be higher, because we don't know how many in the infected population as of today will recover. One could for example calculate the death rate as [Number_of_deaths.today]/[Number_infected.x_days_ago]
I don't really know the "x" to use in this circumstance, but just using 7 days (since a lot of deaths occurred in 7-9 days from positive detection), the death rate may be about a factor of 2 higher. So about 1% overall. I have been looking at so many different sources in the last few days, I can't seem to find the sites where I got the numbers for the above calculations from. So I might be off by a bit.
For what it's worth, we're seeing a GKE being the main reason prospective clients use GCP at Latacora, to a point where I'd say I was surprised if someone was on GCP but _not_ using GKE. Obviously that's a small subset of all companies, but GKE does seem like the goose that lays the golden eggs for them, at least insofar they care about startup market share.

I also think of them as the second, inferior cloud, but they're almost certainly the better k8s hoster. If you're serious about running k8s on AWS, there's a good chance you're doing something like CloudPosse's Terraform-based setup, not EKS.
> AWS, for example, begins with high prices and then lowers them over time. It costs money but you know the maximum.

Past performance is no guarantee of future benevolence or reasonable behavior.
He responds to the claims here - https://www.bbc.co.uk/sounds/play/w3csz3s6

I would rather people over-compensate on sleep than under compensate.

Being sleep deprived while driving not only puts your life in danger, but also the lives of others on the road. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808128/
This is really disappointing. I've been a big proponent of GKE not only to my employer but to my friends as well. I think it's the best Kubernetes implementation available. The justification for a management fee b/c there are abusers just feels like an excuse for making some extra revenue. Truly with Google's prowess you can detect and deal with abusers without having to raise cost for everybody. I'm worried this is going to dampen the momentum of Kubernetes adoption unfortunately...
No Time to Die Release Pushed Back to November Amidst Coronavirus Fears
We’re in the same situation — we’ve engineered for minimum provider-specific dependencies but GKE LoadBalancers were where they got us via arm twisting as well. There is no way to expose a cluster to the outside world in a production environment otherwise.
I interviewed the founder here https://www.skmurphy.com/blog/2019/08/12/tim-lombard-launche...
Save them right now and have them as an insurance against if things go really bad and you have to go to a crowded place.
Thank you for the feedback. The management fee is per cluster. You are not billed for replicated control planes. You can use the pricing calculator at https://cloud.google.com/products/calculator#tab=container to model pricing, but it should work out to $73/mo regardless of nodes or cluster size (again, because it's charged per-cluster).

There's also one completely free zonal cluster for hobbyist projects.
The FDA already allows lesser standards for efficacy for rare things. Which is why there are a lot of treatments for rare things - once you are on the market you can "wink wink" tell doctors about the more common thing you also work on.
I see this a lot but there obviously have to be some kind of effectiveness curve for masks below N95.
> There is a real cost to not approving good drugs in order to avoid approving bad ones.

Do you have any evidence for this? Seems to me like a classic shibboleth of the pharma guild.
That's really impressive. Thanks for sharing!
Crypto Influencers’ Judgement Day. Time for Crypt0’s Cat to Get Out of the Bag
Gcp is not gke. In my opinion the gke offering fromg gcp is the best right now.
You're making the mistake of thinking that the RCMP is a single, well-organized entity. They are not. It is entirely possible that the people who made the statement that the RCMP wasn't using Clearview had no idea that another department was actually using it.
Regular surgical masks won't protect your from inhaling the virus, but they will protect you from rubbing your face and nose 100 times a day with contaminated hands, without even noticing it. I wouldn't dismiss their efficacy.
> first sign of trouble of any kind with a new COVID-19 vaccine

Like what?

Vaccines do not cause autism.
When people are dying in mass numbers from not being in the trail though...
Huh. Wonder where you heard this?

Perhaps you missed the recent American Academy of Family Physicians survey on the topic?

Here is the NBC recap:
https://www.nbcnews.com/health/cold-and-flu/millennials-leas...
See also: https://news.ycombinator.com/item?id=22485679
I can agree with that not "far outweighing", but those are mostly home fires : https://pediatrics.aappublications.org/content/105/6/1355#re... not "activities that children engage in"
She is literally a diligent servant. Her job is to be a servant and she is attentive, hard working, cares about her job and the family and the house. I don't see how accurately describing her as a diligent servant shows any of my biases.

I don't think the film is the good poor versus the evil poor. I think the film is something like a rich person's horror story - the poor hold you in contempt, they're lying to you, they're parasitic off of you, and they're a danger to you and your children. Even worse, they're in your home!

Your interpretation of the film seems explicitly rejected be the film itself as I explained above.
Human trials cannot be optimized away, but they sure can be optimized. For example, you can do away of IRB reviews, which require lots of effort on the side of researchers, take lots of time and heavily restrict what researchers can do, but which ultimately aren't necessary to run a human trials. Of course, IRB reviews have their purpose, and doing away with them altogether in normal times is most likely a non-starter, but in emergency pandemic time having drug earlier might justify lots of risk of harm to trial subjects.
All the people who were made fun of in middle school for being a 'mouth breather' will have the last laugh.
+1 for /r/earthporn. Lots of truly fantastic photos there. My only complaint is that many of them aren't terribly high-res. The cameras they shoot with are surely high-end DSLRs, but then for some odd reason they downscale them to 3000x2000 or even lower (1500x1000 sometimes). But many of them are very high-res.
In what way are they a broken concept? What justification is there for serving HTTPS in a way users can't expect to consume?
Has anybody asked Elon Musk if he wants to show off what a Falcon Heavy can do and maybe get some other billionaire to pitch in for operating capital?
Destination Uranus Rare chance to reach ice giants excites scientists
"The contents of core memory are retained when the power is disconnected, so it's likely that the module still holds the software from when the computer was last used, even decades later."

A useful feature if the vehicle containing the module is involved in an accident and ends up on the ocean floor. A successful core dump would reveal the state of main memory at the instant power was lost.
And as evidence, there are numerous known bad side effects from prior rushed vaccines. The risk is very real.
Do you also have occasional outages because the load balancer gets into a confused state and changes take 10+ minutes to propagate with no re-course other then than to destroy and re-create the entire resource?
Anecdotal, I know, but for prospective Latacora customers this is absolutely not reflected in market share. It's AWS first, GCP second, Azure very distant third. I'd happily believe Azure is dominating in some segments where MS showers prospective customers with millions of dollars in credit, but IMO a blind person can see Azure does not have the product offering to warrant a "completeness of vision" that is right on the heels of AWS.
They are going to, but they need "5G" to be complete for them to do so.
It's 72$ not 300 and the first is free.

I'm not sure what your usecase is that you would choose gke and you are worried about 300$ per month infra costs.

For Corp we use gke. For private I use selfhostet k3samd for our startup asuper cheap digital ocean cluster.
So some comments here say 60-70% global infection [0] and 3-4% death rate [1]. Is this really possible? That would be like ~150 million deaths.

0, https://news.ycombinator.com/item?id=22485485

1, https://news.ycombinator.com/item?id=22485692
In the UK (and, AFAIK, across the EU) we have IFAs (Idependent Financial Advisors) who follow rules, such that they are nit permitted to get kickbacks from investments. Does such a thing not exist in the US?
Surgical masks are effective against droplets from coughing and sneezing.
This article describes one: Swift/Go/Ruby/Python differ from C++/Java/JS/C#/PHP on & vs && vs ==.
I'm not sure I would call them impractical for everyday wear. I wear N95 masks when commuting during active wildfires. The news always says not to wear them because you won't put them on properly, but it's really not that hard to ensure the fitment is correct. It's not like the construction workers that wear them occupationally are rocket scientists.

My partner is more vulnerable to respiratory problems and has always worn N95 masks when in public during flu season. What's changed now is she gets all kinds of shit from people because they think she somehow hoarded masks away from healthcare workers. We've had boxes N95 masks for years, but now we're assholes for hoarding...
You are now breathing manually ... forever.
Aren't those more or less off the shelf parts these days? NASA should have the know-how to finish the final details on a satellite like that.
This is a hilariously wrong sentence in multiple ways.

Hemp :is: a strain of cannabis. You may have meant to say 'THC producing plants' which would still be technically wrong.

While sensamilla is probably what most people are used to these days, that is not to say seeds are not involved / don't appear in capital C cannabis.

I would bet $10, based purely on the deadpan authoritative delivery of completely factually wrong information, that you are either American or British. Close?
Something similar happened to me as a kid, I decided to swim from our boat to the shore of the lake, got exhausted 100 meters from the shore. Before going in full panic mode I remembered you can basically float indefinitely on your back with very minimal effort and did just that until I was calm and rested.

Turns out our mandatory swimming lessons from the age of 8 weren't as useless as I thought.
> Is this how people typically write a paper to Medical Virology?

I wont assume that (I am software engg.)

I see where you are coming from. Here is my perspective, think of this like a outage of your service. No one has exact answers so team starts to dive in and starts sharing what they find.

These findings mostly prune the "solution space" of the problem.
Some countries and states with pool culture legally require a fence around all pools. As far as I can tell, New Zealand has a legal requirement for a fence for over 30 years. There is a little more info on other countries here: https://en.wikipedia.org/wiki/Pool_fence
Unfortunately, while that may be what's needed, many do not trust the current administration to execute on such extreme measures properly or appropriately.
It's kind of ridiculous internal load balancers can't get automatic certs. We've had to do a stupid dance just to get certs via the LE DNS challenge out of band, and then regularly install them on internal LBs.
Corellium ports Android/Linux to iPhone 7, 7 Plus
My layman's understanding is that any barrier will stop some percent of most things. In the case of small, airborne particles, this stopped percentage of already-dry, floating material is very small. That means inhaling through them is relatively ineffective at stopping you from inhaling the particles.

When you exhale it is more wet and the moisture causes the barrier to catch more of the airborne particles. The barrier also catches any more-solid material that would otherwise land elsewhere, providing a mechanism for the particle to spread.

This means the net gain for wearing them to keep from catching the disease is relatively small compared to the gain by wearing them to prevent the spread if you may have been exposed.
These types of devices have existed for a while with a dish at least. You're right, at this frequency you need LOS and there's little forgiveness there.

Current products don't really intend (to my knowledge) for you to connect a client directly to this antenna, rather they're meant for both to be in a fixed location properly aligned to each other, then they go to the access points for the clients.

Like the other's mention, this is useful for many environments with multiple buildings, easy example is a shed out in your backyard.

Obviously if you could run a copper/fiber connection out directly that'd be better, but these are for situations where you can't.
That was an extreme example,the point is that kids can end up in the water in unexpected ways. Even parents that would never intentionally leave children in the water alone can end up in a situation where a child is unattended in the water. Perhaps a better example is when you have 4 kids to keep an eye on at a public pool, and you lose track of one while dealing with an injury to another, or reapplying sunscreen, or a number of other reasons to be distracted. Or what about the situation where you send your kids outside to play and they sneak back to the pool? No sensible person would let their children into the pool alone, but it can absolutely happen to even the most careful adult.
If you don't serve the same content on :80 and :443.

For example, you might be running a Tor relay node which would serve the node directory list on :443 to help people bypass firewalls, but also be using it as a useful and legitimate web server in order to prevent organizations from blocking it wholesale.
I've had sites not work in anything but chrome, specifically one of those bicycle registry sites. I think it was fixed.
Hey Seth, I know you used to work at Hashicorp on vault. I think Vault recommends that if you want to deploy it on Kubernetes, it should have the cluster to itself.
Boots halts Advantage Card payments after cyber-attack
You don't trust Italy with their numbers?

Last time I checked it was around 3% there.

https://www.aljazeera.com/news/2020/03/coronavirus-deaths-ch...
Same! I still manually provision some certificates just because LEGO/etc. just don't work with GCP + Google Cloud Load balancer! And the docs for the entire subject are useless..
I linked two incidents. The first one required a trending HN post to get resolved. The second, the developer never got their data back.
Seth — I appreciate you being here to take feedback, and for the clarification as well. The very surprising email I’ve received this morning is very hazy on the details, and the docs linked from the email are not updated yet.

The main issue is that not charging for the control plane and charging for the control plane leads to two very different Kubernetes architectures, and as per your docs, those decisions made at the start are very much set in stone. You cannot change your cluster from a regional cluster to a single zone cluster for example. So you have customers who built their stacks taking into account your free control plane, and you’re turning the screws in by adding a cost for it — but they cannot change the type of their cluster to optimise their spend, since, per your docs, those decisions are set in stone. That’s entrapment.

You should keep existing clusters in the pricing model they’ve been built in, and apply this change for clusters created after today.

That said, many of us made a bet on GCP. For us in particular, we made a bet to the point that our SQL servers are on AWS, but we still switched to GCP for ‘better’ Kubernetes and for not nickel and diming, since AWS had a charge that looked like it was designed to convey that they’d much rather have you use their own stuff than Kubernetes. It is a relatively trivial amount, but it makes a world of difference in how it feels and you guys know more than anyone how much of these GCP vs AWS decisions are made based not on data sheets but for the ‘general feel’ for the lack of a better word.

AWS’ message is that they’re the staid, sort of old fashioned, but reliable business partner. GCP’s message, as of this morning, is stop using GCP.
This is penny wise pound foolish GCP.
"A classic is something everybody wants to have read, but no one wants to read." -Mark Twain

Many want to have had done a startup.
Fascinating to see so many salty comments, let me share my feedback. I like the concept of having a snapshot of the content at the beginning of the article. Found myself clicking on quite a few of the links out of curiosity, including a well-written piece by Harvard Law on the Wells Fargo scandal.

I would have preferred that at least half of the tools were already available on the article (@Azura), although they have some tools in the solutions page that were not listed in the article.

For any management related topics, I am always reminded of the usual and timeless (@JSeymour): How to Win Friends and Influence People, 7 Habits Of Highly Effective People, Thinking in Systems: A Primer, The Effective Executive and Failing Forward.
It could be worse than that once the hospitals are overloaded / out of equipment needed for artificial respiration. From the numbers coming out of China ~20% of cases are "serious," ~5% "critical."
But you do intend to directly profit from it.

If you just start out selling tractors that are only equivalent to the incumbents and with all the same restrictions, who is going to buy them? The reason people want to buy from you instead of them is that it's possible to repair your tractors. And if people are buying from you, you're making money.

Maybe a few years later the investors decide they might like to make even more by closing things up, but by that point the software is already published for free on the internet (which was what got customers interested to begin with). So if they do all that happens is that someone else starts making repairable tractors, which people still prefer, using the software which is by then free and already exists.

Have people not noticed how much money Amazon makes out of "your margin is my opportunity"? Taking market share from the old guard by making less (but still some) profit per unit is a great way to make money.
It's a shit ton more work, and the government takes about 18 months to come up with the annual budget already. The only reason it works at all is the ability to let hundreds of thousands of small projects coast on their last budget.
Same goes for metal, your data center can suddenly increase your prices massively or go bankrupt.
I'm in Italy, and we had a very vocal no-vax movement in recent years. Since coronavirus they disappeared
Is it? "Socialism" and "Communism" are used interchangeably in American politcal discourse as a blunt way to distinguish between democracy and capitalism versus dictatorship and collectivism.

South Korea itself was a dictatorship until the late 1980s and received preferential treatment in trade talks in the cold war era with Western economies due to their unique role as a buffer against Communist expansion.

This level of privileged access would not be available to less strategically important countries in a 'free market'. Plus SK already provides a level of socialist services that a failed state like North Korea can only dream of.
I think a much more likely scenario in the event of a bad plague would be that angry mobs will put anti-vaxxers up against the wall and shoot them.

(I am NOT advocating this! Looking over history that seems to me to be a more likely reaction.)
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