skysight-inc/HackerNews huggingface dataset:
I think this new policy would make it simpler for your case because it would probably just turn into an automated refund vs talking to multiple parties and support tickets.
Quinolone is some nasty (but effective) stuff. Chloroquine has a more benign side effect profile.
I spent 6 weeks in the ICU, half of them in a coma and intubated, it took me weeks to feel my brain was working normally when I was released to a normal recovery floor. I was confused, a little delirious and my memory was screwed up.
> nextcloud

The one I was thinking of, but the other two I've only maybe heard of one.
There's many levels of pattern matching, and computers have to start at the bottom. First you have to convert the real world into a form you can use, like vision or voice recognition. Then you've got to parse that into concepts. Then you've got to analyze those concepts for patterns.

Most of our software is still struggling at stage 1, and our software is so poor at pattern matching it can't detect obvious stage 1 failures at stage 2 or stage 3. We can make a program to recognize species of birds from photos, but it will also tell us that a bunch of static is (with 99.5% certainty!) a robin.

I don't think any of the experts I know are at any risk of being replaced by AI in their lifetimes.
Thanks for that thoughtful feedback.

> but I think it could certainly generate a more thoughtful discussion than what I saw on this weekend's post.

Thanks, I'd like to think it's not such a mundane idea that it warrants no discussion at all, hence my desire to resubmit.
https://doi.org/10.1186/1743-422X-2-69

>>We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

>>Chloroquine is known to block virus infection by increasing endosomal pH required for virus/cell fusion, as well as interfering with the glycosylation of cellular receptors of SARS-CoV
The complaint, linked above, shows how the investigation went forward. He was not careful; the test accounts were associated with his identity directly.
Making a Todo App in Svelte
There's also the Getty Open Content Program:

- https://www.getty.edu/about/whatwedo/opencontent.html

- https://search.getty.edu/gateway/search?cat=highlight&dir=s&...
https://www.medpagetoday.com/infectiousdisease/publichealth/...
How to Build and Maintain Great Investor Relations
> would be the largest project in human history

And it's still smaller than what you suggest. Think about that.

> Writing some code that makes a process work a little more efficiently doesn't make a meaningful impact on overall power consumption.

Sorry, you're saying an engineer cutting their personal meat consumption is more effective than that same engineer making entire power plants more efficient? I think they should be doing both but the latter is far more effective, for that one person to do.

> all human beings need to participate

Cool. Let me know if you figure out how to do that.
That’s not exactly what he is aiming for; the quote is most likely related to Instagram which reached a $1bn valuation with ~10 people. A lifestyle business is worthless to VC (and unsustainable if it decides to take VC money).
My friend over at team.video works mostly from home and swears by the Roost Stand.
He didn't say easy startups couldn't be successful - just that Insta had to stand up to several orders of magnitude more competition than a 'hard' startup was/would have been.

As a matter of survivorship bias, it would be shocking if there wasn't some surviving 'easy' photo-sharing startup. But looking at it prospectively, I think his point was: you could be fending off 9 competitors rather than 999 competitors, not knowing in advance if you're going to be the 1 survivor.
Not sure how many here have tried it but it takes all kinds of tricks to scrape Bloomberg reliably. Not surprised they're doing something like this.
Hmmm. About 9 months ago I was looking to add IoT functionality for a large industrial device. I looked at Particle briefly, but TBH, they seemed more focused on the "maker" market than industrial applications and that would definitely be a negative in the market the product is going to be sold into.

I don't know if I missed it before, but the products I'm seeing on your site now really look more suited to what I need than they did back then. I've done a lot of network programming and IoT work, but since connectivity is such a minor feature of the machine, it would definitely be preferable to have a smart module to abstract away most of it for me.

Oh, well. There's always next time :-)
That's not going to happen. Nor are thousands of nuclear reactors going to be built in 10 years. Nor is the US going to cut its primary energy use by 60% in 10 years. Nor is the combination of all-of-the-above going to make the US carbon neutral in 10 years. Nor should we give up on continued incremental progress after another 10 years have passed without fully solving the problem.

It's always possible to make climate change even worse by burning more fossil fuels. Regardless of whatever dangerous threshold of emissions has passed in 10 years, it doesn't make sense to resign ourselves to burning the rest of the fossil fuels. I'm afraid that the hardline "we need to have solved this emissions problem in 1X years" rhetoric is counterproductive. It asks too much and will prompt fatalism and/or cynicism when the deadline has passed, there are still billions of living people who need to make decisions affecting the future, and the problem still isn't "done with."
London firms sending staff home amid coronavirus fears
It's 4:01 EST. Major indexes mostly down, NASDAQ up .15%-.2%. Looks like a normal day on the market. Certainly not a "bounce".
Your credit card provider might be happy to help you block further transactions with NYT and this is the better path to take. If enough people flag this behavior with their CC provider, it will eventually lead to penalties imposed on the business.
The claim was "no eco-system to speak of". There is clearly an ecosystem to speak of. It might not be a healthy ecosystem, and we might speak of it poorly, but it exists nonetheless, and in fact exists in a greater capacity across that whole range of categories than what a lot of other "popular" languages can claim.

"Machine learning" is a perfect example of how out-of-touch that claim is considering that Lisp was the language for AI research until very very recently.

> mcclim – really?

I guess you didn't see the link right below it with the dozens of other bindings to other popular GUI toolkits.
Ethereum Multi Level Marketing Schemes: Into the Rabbit Hole
How to Use ESLint with TypeScript
> Counter to what the author is saying, you do need a degree or some level of measurable expertise to start a hard startup, because not only do you need the expertise, you also need the credibility to get people to work with you and you need that solid team to get funding.

Interestingly, this criterion causes Microsoft to be in the "Easy Startup" column. (Facebook too, but that seems more correct.)

The Elizabeth Holmes example is also interesting to consider. Lack of degree in a hard field was no barrier to raising a ton of money.

> In my mind, a good one is Intel. To that end, how many microprocessor startups actually ended up succeeding at the same working on some fundamental and challenging things?

Nit: Intel's first products were memory, not CPUs.

https://www.google.com/search?q=intel+first+product&oq=intel... )
Things QA testers wish programmers understood
My dad.
> There is probably an explanation for this that doesn't boil down to "FB watched our GPS and noticed our phones sat next to each other at the same location for several hours," but it still felt sufficiently creepy to make me uninterested in sticking around to figure it out.

That's exactly what happened[1].

> "Location information by itself doesn’t indicate that two people might be friends," said the Facebook spokesperson. "That’s why location is only one of the factors we use to suggest people you may know.”

1. https://splinternews.com/facebook-is-using-your-phones-locat...
Show HN: Design Collaboration for Software Teams
Mapping Coronavirus, Responsibly
The numbers I have seen were between 2% and 3%, higher for males and lower for females. I did not seen sub 1% anywhere.
> Don’t fall for their “mission” nonsense. It’s a monstrous lie designed to keep funneling tremendous amounts of money to the people at the top.

100%. I've recently run into this with companies peddling that they're "mission-driven", as if that's somehow a replacement for compensating their employees appropriately. If it's a for-profit company then this "mission-driven" term is absolutely nonsense because the cap tables prove the people at the top with the large chunks of equity aren't foregoing any compensation to achieve this "mission".
Two big threads from 2017:

https://news.ycombinator.com/item?id=14819622

https://news.ycombinator.com/item?id=14889109
> One of my personal annoyances with the tech community is that we have a tendency to try to work around any governmental problems as if that solves the issue while making no attempt at fixing the root cause.

Agreed. We need to produce technical solutions, and effect policy solutions, and get a lot better at PR and rhetoric.
Are there reasons to believe that human clones are different in this regard from animal clones? Animal clones are viable and live as long as its parent.
Ok, but the same arguments could be made about the terms "refactor" and "plane" (as in control-plane/data-plane) but we seem to manage to cope with the overload.
At the point where the Bitcoin was converted into bank account funds.

There's a reason why money laundering is a criminal specialty.

He needed to stop stealing and fencing the goods before getting caught, wait a few months or years without doing anything shady at all, then start dripping the ill-gotten gains into his account alongside an entirely legitimate cashflow, a little bit at a time.

Buying a mansion and a roadster out of the blue is an "stupid criminals get caught; all criminals are stupid" type of move.

Even if all you know of crime comes from the movie theater and television set, you'd know that after the airport job in Goodfellas, some of the guys got whacked for violating the "don't buy anything!" edict. In Breaking Bad, the car wash and the Pollos Hermanos chicken restaurants were necessary for laundering the methamphetamine revenue.

I think the mention of Bitcoin mixers was just chaff. The guy was caught because his bank tattled on him, and the IRS didn't buy his flimsy sourcing story. If he had just kept the proceeds as some variety of cryptocurrency, he might not have gotten away with it entirely, but the investigation would probably still be ongoing--the questions remaining to be answered being, of course, "how much did he steal, exactly?" and "how do we seize and forfeit those funds?" Someone might know that he was stealing something, but they wouldn't necessarily know how much.
It looks like the opacity on the text is set to 0. You can't even read the content. Does anyone else even notice this?
> Besides, Gilead, much like every other large pharmaceutical company, has patient access programs to ensure that anyone who needs their medications can get them

Not if they're on Medicaid or Medicare[1], which some providers through those programs only very recently began to cover the medications due to lawsuits against them.

Also, the co-pay coupon card only covers up to $7,200 in co-pays per year[1].

There is also the income gap where someone could make too much money to qualify for their program, despite having no insurance, bad insurance or catastrophic insurance plans. A contractor responsible for their own health insurance might find themselves in that income gap.

And this program is at the discretion of Gilead, who can deny, change or discontinue it at any moment.

[1] https://www.truvada.com/how-to-get-truvada-for-prep/truvada-...
Thin-film solar cells generate as much energy as regular ones for the first time
Revenue on it’s own is meaningless in this context. All those US drug advertisements are paid for with US heathcare spending along with endless paperwork, insurance profits etc.
If it says "KEEP AWAY FROM FIRE" in red lettering on the label, it probably doesn't have flame retardants. Though there may be false positives to this test (but no false negatives), so preferably look for something like no flame retardants.
China.
By the time COVID hits your zone, the chinese will have it contained.
Plus, most of the expertise fighting the virus is there.
Urethane foam, aka "solidified hydrocarbons" should probably be banned...

https://www.youtube.com/watch?v=snlhECzj1E8

https://foursevenfive.com/blog/reason-foam-fails-2-unaccepta...
I found this exchange amusing as well, for a slightly different reason. The gist of his point was that "who needs this level of encryption, other than maybe the military?".

Substitute guns instead of encryption and see how that fits.
Ask HN: Workplace has Poor Knowledge Management – How to deal with it?
Hi all,

I got a pretty decent desktop support gig a few months ago and while on the whole it's been pretty great, I feel like my development is stagnating because the place has pisspoor knowledge management. Every process or procedure or general knowledge/bit of info is in a series of non-curated OneNote books that are written by anyone and everyone. Furthermore, there are a million ways to do one task and everyone is certain that THEIR method is the right way.

At this point, I've dropped the ball on a few things, missed some simple steps in certain important processes because the documentation was basically written in crayon, and people are starting to resent me for having to pick up the slack when I mess up.

We are a few months away from rolling out ServiceNow and I've been granted access as Knowledge admin in effort to build out the knowledge base. This is great, but in the meantime, people think I suck, and I'm starting to believe them. Halp!
I'd much rather have a performance oriented blog post have at least a few performance data points (even if put into context): simple vs fast ... but by how much ?
Your backend can be a reverse proxy that authenticates requests then passes them off to CouchDB (or PouchDB, since that also runs on the server). I have an example up @ https://github.com/daleharvey/noted. The server is 200 lines and does signup / email authentication etc.
The first point on your list is something that I come back fairly frequently when reading through blog posts like this, or (for example) listening to things like TED talks. I understand that there's a need to stand behind any given thesis, but it seems to me that there is often a lack of distinction between "I'm claiming this to be true primarily based on my experience" and "I'm claiming this to be true based on widely-accepted external factors, like peer-reviewed papers, industry standards, statistically-significant trends, etc.".

When people don't meaningfully differentiate between those two positions while communicating, it passes the burden of deciding which claims fall into which category onto the reader. And since I'm then unable to distinguish if the writer themself recognizes that difference, I find myself less easily able to give any of their claims the benefit of the doubt. That isn't a recipe for taking their advice or conclusions to heart.
A method I've seen tossed around is that they'd just add a "ghost" user as a silent participant to all conversations.

I'd like to think this is difficult with Signal's model, though.
The part about tech geniuses being able to solve a problem that can't be solved without violating principles of mathematics.

You probably don't think you said that though, because you missed the point yourself. It's a common mistake. You're in good company, plenty of smart politicians and national leaders have the same misconception. It's often stated in terms like "if we could put a man on the moon, all the smart people in Silicon Valley should be able to put their heads together and figure this out." But it doesn't work that way.

Aside from being wrong, which in itself doesn't deserve a downvote, it's also poorly thought out and a seductive yet destructive line of thinking, which arguably does deserve one.
But the transactions between players are zero-sum... An interesting, related point: zero-sum trading games (even ones based on chance [1]) always devolve into pareto/power law distributions when bankruptcy is a possibility. More a matter of natural law than "evil" capitalism

[1] trading game simulation: https://youtu.be/CsRLVZTYpGo?t=313
But open source could be commercial, right? So is it about free software?
Granted regarding wind, but there are a lot of coastal areas in the world and other windy non coastal regions as well. As for solar and latitudes, this is primarily an economic choice, so while yes some areas of the world will produce more watts/m^2 (see global maps of Global Horizontal Irradience), solar utility generation can still make economic sense |in or near a lot of populated places around the globe. Sure, high density islands would be a silly use of space for solar but being islands, wind would likely make more sense|.

And yes, transmission of power is also a problem for places like Australia being so large, but even with this people are genuinely looking into building large _international_ electricity connections under sea between north of Australia and Singapore [0] backed by 10GW of solar generation capacity [1], a $20B investment that they are willing to bet will _make_ money, not heavily gov funded.

A lot of people are also looking at hydrogen generation from excess renewable power as another way to recoup some profit when grid generation prices go to 0 or negative. Deciding _when_ to do these kinds of activities is largely where _climate tech_ can help out. Again, even relatively small improvements allow for larger shifts if what we do and can have a large impact of investment including how attractive the scaling of these technologies can be. Because energy generation and consumption are such fundamental parts of modern life, being clever with how you do both of these things can lead to whole different approaches. As clean energy generation costs drop there will be other carbon net negative (maybe negative) activities that become economical, creating a space where money can be mode is the fastest way to accelerate change in the modern world.

Some of these choices will no doubt cause their own problems that will need to be solved, but at this stage world needs to look towards harm minimization, and quickly when it comes to the climate crises. With hindsight I'm sure we'll be able to look back and highlight ways it could have been done better, hell we can do that now but those with the power to make that change seem unwilling to show leadership.

If you are a programmer/technical minded person, climate tech is still a positive contribution and I think is an industry that will be growing. If you are a politician, yes, you'll likely have the _chance_ to make a far larger impact and all power to you, but I'll be doing what I can with the skills and knowledge I have.

[0] https://www.suncable.sg/

[1] https://reneweconomy.com.au/nt-government-backs-10gw-solar-a...

| EDIT added for clarity
Strong agree.

I found Sam Altman's writing on quora and followed it off-and-on long, long before I found out "who he is." And his advice is so overly-positive and one-note that, honestly, I thought he was a snake oil salesman or self-help guru. I would never have guessed he was actually a VC / successful entrepreneur.

Frankly, his arguments and writing continue to sound like Self-Help Guru shined through the lens of SV VC to me. Nuance isn't really on the table.
> If the answer is that you'll blacklist the spy's DNS servers, then how is that any different than the situation with DoH?

There are two differences that DoH brings up about this.

The first is that because mainstream DNS providers are beginning to support DoH, there is no need for anyone to set up their own private DNS server. In fact, they wouldn't want to -- much better to use a real one that can't be blocked without causing unacceptable collateral damage.

The second is that DoH hides the entire interaction from me (unless I do what I did -- implement a MITM proxy to decrypt all HTTPS traffic).

> DoH isn't adding any value for the spy unless you are doing deep packet inspection of any packet that contains DNS data.

Sure it is. It effectively disables a layer of defenses from the spies.
Prices and consumption are linked. US drug companies spend a lot on Advertising to promote pill popping, but that’s not free. Further, they rarely collect the full sum from insurance companies or Medicare.

It’s the odd case of people in the US avoiding heathcare due to costs, where others seek it out when unnecessary.
This is a dark pattern that's all too common on slightly sketchy small businesses. Slightly disappointed, but not terribly surprised, to see that it's also common in "mainstream" newspapers.
The alternative is that they're just that evil, that they're doing it for the lolz. So no, it's not strict evidence.
It looks like it works on the brave browser, but not chrome or firefox
Huh?

First off citing yourself isn't an elaboration. Second if you are arguing that one-time-pads don't work / won't work in modern times that goes against our entire understanding of certain bits of cryptography.

You'll need to yield some real sources first.
A mission and a reasonable distribution of equity with fair terms do not need to be mutually exclusive, that's how I read the original comment.

If the C-levels are still getting massive chunks of equity with tiny strike prices while you get 0.01% and a 90-day post-termination exercise window and a massive AMT bill, then this talk of a "mission" is vacuous and likely a diversion from the fact that you as the employee are being under-compensated.
what is profitable for the individual may not be profitable for the group.
Will this talk / transcript / slides be posted somewhere?

I would love to attend in person, but I cannot due to schedule conflicts.
If someone with domain experience thinks you can't do what you're trying to do or are doing it the wrong way:

1. They're correct and you should not get a check.

2. They're incorrect, and you wouldn't want them to be the person writing the check.

3. They have good reasons for their concern which you had not yet considered.

All of these sound like good outcomes to me.
I think you're underestimating

a) how hard it is to make a library like this that's any good

b) people will want to support them anyway

$249 (or $599 for a team license) one time is really very little if it does what it promises.
Speculation, no evidence.