skysight-inc/HackerNews huggingface dataset:
"If I remember their argument correctly, cells that "only" reproduce anarchically present little danger (benign tumor) if they don't also do so at an abnormally fast rate / metabolism."

Forgive this (very tortured) analogy, but I think there is a lesson here for would-be extropians who think society will simply tolerate a few vampires here and there.

Specifically: they'd better be living lives of quiet, impoverished contemplation ...
Just wait until somebody offers you "signals"... hahaha
I don't think that argument fails, generally. The availability of rice, beans, and potatoes in bulk quantities on Amazon still does not make them accessible to the poor. The poor are frequently unbanked, and prepaid card schemes with predatory fees are not an improvement. They also are more likely to live in neighborhoods where packages are stolen.

Apart from that, if people eat nothing but the foods that can be stored unrefrigerated for long periods, they're going to end up with health problems, even some of the same ones caused by processed foods.
Am I the only one using Google's own password manager? Ideology aside I can't think of someone with more engineering resources to prevent hickups and breaches. Are there any benefits of other pw managers I'm missing out on?
My initial thoughts when reading were cynical - along the lines of "this person is trying to look clever and sell freakonomic / pop-science type books, but are the statements and conclusions based in fact, likely to be correct or are they useful to me?". Since I can't answer I didn't read on.
Is https://bitbucket.org/jibalamy/owlready2/src/default/ the standard py lib for accessing these?

Is there a recent tutorial on querying the ontology from the terminal? I found a few on yt, this one is 5y old: https://www.youtube.com/watch?v=5DCS9LE-8rE
Here are links to the two videos:

https://www.dropbox.com/s/jkyxlkh0aa5d24m/IMG_5402.mp4?dl=0

https://www.dropbox.com/s/oxgwpe6bn39p0re/IMG_5404.mp4?dl=0
There is no body temperature measurements in Apple Health from the Apple Watch, but that would definitely be an interesting data point were it available.
Understanding Neural Networks
Wellingborough Driving Test Rtoutes No. 01
A lot of these problems postdocs are running seem to be the result of an inefficient allocation of talent by our current educational system.

All the smartest kids get tracked into getting math and physics PhDs and by the time they get to the postdoc stage it just becomes this insane impossible rat race tournament.

I saw the writing on the wall and got out of academia as soon as I defended my utterly mediocre PhD thesis in math.

I jumped on the data science wave in 2013 and all of a sudden everyone thought I was a genius for being able to run model.fit() and interpret the results.

These tracks that funnel you into cutthroat tournaments just seem like bad places to be.

Already data science is starting to become more of a commodity skill set.

Instead of trying to outcompete everyone I’m keeping my eyes open for my next big opportunity.
It is nice to have tools that don't require 30 seconds to boot up, just so you can view some xml (Looking at you visual studio). But the recommendation of vi or emacs...just why? I scratch my head when people recommend 30 year old tech.

Those who use vi and emacs to their full potential are that generation of developers who grew up with those tools. Nowadays, why wouldn't you use something like VSCode as your main text editor? Atom? Or even n++? Unless you are confined by your job to an sshterm or something. If you want to LEARN a text editor you might as well pick one of the modern ones with all the nice modern QOL updates. The tech-flex of developing in a terminal is so dumb.

And VI? Why not VIM? VI is like recommending ANSI C over C18.
Take him with a grain of salt, since he's just a single researcher in a big field laden with quackery and crackpots but I thought his approach and reasoning were refreshingly clear headed. I recommend his other UFOlogy books very much at least for the sake of entertaining curiosity about something many people don't read about often.
Julia: Abstraction in Technical Computing (2015) [pdf]
Even if you can see his face clearly, how will you find him? It's just a face.
Agreed - I've had a lot of conversations around marketing for SAAS companies and tried to put them into more of a visualization:

https://docs.google.com/spreadsheets/d/1l-0VLKWIzqu2dwyxmmNJ...

Should be noted that this is really from the perspective of B2B SAAS.
That ups the cost by a LOT though, so people don't. I have no desire for a "smart home", smart tv is about it, I have some external wireless cameras. No camera in my home except on my phone. You can't hack it if its not there.
His Name Is Harry Potter. He Is the Boy Who Lived
Big Tech Battling for Social Impact Spotlight
If you wish for a dissenting opinion on the MongoDB, I enjoy the writing of Kyle Mitchel at /dev/lawyer

https://writing.kemitchell.com/series/SSPL.html

Kyle is a advocate of dual licensing ("selling exceptions") and has even created License Zero [1] which is attempting to allow the creation of npm libraries which are dual licensed and an automatic command line tool to pay developers.

[1]: https://licensezero.com/ see also
https://writing.kemitchell.com/2017/09/12/The-License-Zero-M...
Show HN: My Collection of Encryption Keys
The Tanab
Even 'Real 3D' is a misnomer. I work in the industry and we call it 'stereo' for a reason: it generates a feeling of depth but your eyes never have to converge so, via either route, your brain always knows that it isn't reality.
Digital De-Aging: Star Trek's Capt. Jean-Luc Picard in the Picard Series Trailer
> Except they might have read an article on CNBC or Fox that was based on a twitter thread. That's where it actually makes a difference, when it spills over into other media and picks up steam.

Exactly (and what I said in my comment). But it goes further. Take the NYT widely regarded as 'the Paper of Record'. What they say has a great amplifier impact. Ditto for shows like 60 Minutes or even the nightly news in some cases. Most people in media (say in small towns or in less than impressive in any way newspapers) very generally think that is what you aspire to to work for - a major media outlet (in other words some small station person in Idaho is envious of the people who work at the networks like some high school football coach is probably envious of NFL coaches, right?).
2014? That dates how long I've had this Sidewinder X4 keyboard from my reply there, and roughly how long my experience with the Datahand and Plover has put me off buying another strange or unusual keyboard. Specifically the "Truly Ergonomic"/Cleave keyboard which came up in the last year or so for another round of production, and when I googled it found a review by Xah Lee [1] - who no longer uses it - and this guy I'm sure you'll recognise - https://www.sacrideo.us/not-your-typical-keyboard/ - who seems to no longer use it, and both previously owned a Datahand too [2].

I wonder what the incidence of people continuing using their strange keyboards long term, vs. raving about them and then not using them after a few months, really is. And what happened to the guy who bought my Datahand and paid international shipping to get it.

[1] http://xahlee.info/kbd/truly_ergo_keyboard_cleave.html

[2] http://xahlee.info/kbd/datahand.html
I know you are joking but there is probably a good case to have a sensor on every piece of livestock, given how cheap the sensors would be and how it would help to manage things. The govt. could even carbon-tax the methane emissions.
Not sure why you're being downvoted. As the partner of someone who had a miscarriage I was happy to see someone thought of me as well. I definitely also have PTSD from it. I remember my partner being in pain and bleeding and experiencing the sadness of loss on top of all of it. I was scared and lonely and I feel and felt helpless.
A husband friend of mine has told me he often feels sad when he sees our baby boy because the baby is the same age his son would have been had they not miscarried.

A good rule of thumb is to treat people with compassion and support, because you don’t know what they are going through.
Yes, again, I work in the field.

There are many areas where ML is being used to advance drug discovery and other kinds of practical, difficult biophysics problems. Casual readers would do well not to get too fixated on this particular area.
How to Come Up with Profitable Online Business Ideas
Unpleasant things very rarely need to be done or said, but people (me included) are addicted to doing and saying them. We all feel the need to desperately type the first thing that pops into our head (like the sentence I just typed, and I'd argue the reply you gave). If I wasn't allowed to reply to your response for, say, 24 hours - then I might write something useful and interesting. But the internet of beefs doesn't reward that.

EDIT: FUCK! 20 minutes and I've already failed.

EDIT EDIT: Does anyone have any strategies to cope with this? I generally make sure to log out of HN (and have deleted Reddit/Twitter/Facebook etc), and my passwords are always random key-mashing that I forget so that commenting is pain... but still, if "someone is wrong on the internet" - even if it's low (or zero!) stakes... I'm compelled to type some crap back. Logically I know I shouldn't give a shit - but I do. I'm a mook! Is there an escape?!
> Overweight and obesity are associated with at least 13 different types of cancer.

https://www.cdc.gov/vitalsigns/obesity-cancer/index.html
That's framing things from a legal perspective, but even then there are some key legal steps you're missing (and this isn't conclusive at all):

Beating someone based on sexual orientation was recognized as a hate crime first in 1984 at the state level. 1995 and 1998 were when Clinton banned discriminating against gays at the Federal level via Executive Order.

1996 was when Clinton signed DOMA, which is the reason legislation stopped for so many years. Though lately he's tried to conceal that, it prevented GLB rights from advancing for many years. It was in response to states legalizing same-sex marriage.

1993 was when GLB people were first allowed to serve in the military.

1993 was also when Hawaii found bans on GLB marriage unconstitutional (at the state level).

1992 Colorado passed Amendment 2 which specifically forbade Colorado state, county or municipal governments from recognizing homosexuals as a protected class.

1998 Oregon makes GLB people a protected class, preventing people from discriminating against them on the basis of sexual orientation.

1984's National Gay Task Force v. Board of Education partially gutted a law that allowed schools to fire teachers on the basis of sexuality. (NGTF was founded in 1972.)

1977: GLB allowed to work for the IRS and foreign service, GLB activists for the first time invited to the White House.

1960s-1970s: Gerald Ford, for all of his faults, being the first 1900s President to really be pro-GLB.

1970 featured my favorite Nixon quote: "I can't go that far; that's the year 2000! Negroes [and whites], okay. But that's too far!" By 2000, as you can see, things were not much better.

1950s, 1960s & 1970s saw it come into general awareness; lots of protests, including Stonewall.

1901 saw DC make it harsh again; no felony, but a lot larger a fine, no imprisonment.

1892 basically decriminalized it in DC; you get a fine and you pay bail.

1807 saw Indiana make legislation to lessen the punishment for it (although it was the first to be for both genders); 4 years max, a fine, and a felony.

1801 had Maryland making perhaps the laxest law on sodomy ever: <7 years of punishment, the act of cleaning one's town, no imprisonment.

Jefferson failed in 1779 to liberalize his state's punishment for sodomy, but that's probably the first act of legislation trying to go easier on homosexuals. Virginia later passed (I think before 1800) a law that limited the punishment to 10 years.

George Washington brought in a general who was being persecuted in Germany for being homosexual shortly after we won the Revolutionary War, he was never punished, got pension, etc.
Couldn't one develop BiTEs (Bi-specific T-cell engagers) for this receptor?
That would be cheaper and off the shelf for every patient.
The License Zero Manifesto: sustainable software in the open (2017)
Behind the Gas Lamp (2007)
Consumerism, at the least, is dependent on capitalism's core feature, generalized commodity production. So far, that seems true - was there any consumerism in pre-capitalist societies? I'd hazard a guess and say no. If consumerism is further driven by advertising, it depends on capitalism even more. This paper[0] persausively argues that consumerism is a consequence of specifically capitalist society, considered in its historical development.

[0] https://onlinelibrary.wiley.com/doi/abs/10.1002/978047067059...
Ask HN: As a small company, where can I get affordable legal advice?
I have a small side business running a few websites and earning money through ads. I am based in the EU but many of my users are in the US.

So far I have been dealing with legal questions around this myself but I have some questions around data protection and the CCPA that I would like to ask a professional about. I am happy to pay a reasonable rate for a qualified advisor (I guess they'd be a lawyer?) to help me with this but I have no idea how to find one. This would have to be someone reasonably well versed in Californian laws although they could be based anywhere.

Can anybody recommend someone who might be able to help with something like this, or could give me any suggestions for finding someone?
Home, Plus, Pro.

Microsoft figured this out years ago.
Yes, Russia measures temperature in the armpit. Is it really that much colder than in the mouth?

Edit:
A 37 temperature would automatically give you an excuse from school when I was a kid and, obviously, children always were finding ways to cheat. If just putting the thermometer in your mouth worked then either I was in the dark or nobody has discovered this.
Twitter wasn't meant for the way the author is using it, thus it sucks for what he's doing. it's good enough for him and since you can't bring your audience to a new platform with you twitterers just live with it.
"npm-deep" I love that phrase. anyone who suffers a dig around the node_modules folder knows the pain! Ugh! I also used Oracle in the early 2000's, I need hypnotherapy to get over that.
I thought we learned our lesson about "paradigm-changing" scientific results released to the media simultaneous with initial publication a while back. The paper was published today, and only available behind a pay wall. Yes, this is exciting, but what they appear to have is a better way of tagging cancer cells so the immune system will attack them. This is one round of rodent studies in immunosuppressed mice, for which the abstract only claims "enhanced survival". There is no reflection or information from anyone who isn't actively on the team. This is a press release before a funding cycle, not science. "May treat all cancers?" Please.
Having a password manager on mobile is needed, so I need multi-device support. I was really happy with the password manager support the last iOS included. Password entry and persistence are streamlined.
Mammals are tetrapods, which are indeed under Osteichthyes (unless you consider Ostreichtyes to be paraphyletic).

If you look at the cladogram on the wikipedia page I linked, you see a picture of a salamander near the top representing the category Tetrapodomorpha. We (and whales) are also on that branch. Sharks are outside of that whole cladogram, as they are cartilaginous fish. ( * )

In other words, any clade which includes all bony fish also includes mammals.

[*] which means that the most recent common ancestor of sharks and goldfish lived longer ago than the most recent common ancestor of whales and goldfish
They do seem to sell freakonomic/pop-sci books. Nice eye!
People who know what NFS is will be on Emby or similar before I finish writing this comment.
The Tanab
TANAB is derived from a native word meaning rope. Our hope is that THE TANAB will help you keep it all together️Personal & Professional advancement️
Vast majority of new cancer treatments do not end up improving survival times and generally come with significant, unpleasant side effects. Of the small minority that are found to be a net benefit, most are just barely worth it: very modest extension of life expectancy with sufficient toxicity that many well-informed patients will nevertheless decline them.

This is not just chemo either; immunotherapies can be brutal.
So that being said, yes, having the numbers additional that signal a decline in morale for example, is probably not a bad thing to have. If this does not replace actual human contact, because human moral also drops, when they not feel treated as humans anymore and just as numbers.

Agreed. And this is true of every tool... it has a place, and when used properly it can be of benefit. But it can also be misused in a way that is harmful or destructive.
In the late 90s I had a co-worker who managed to wrangle one of these at our office. I think he tried it for a few weeks and then returned it. I solved most of my RSI problems at the time by switching to dvorak.
Ask HN: Computer Vision Startups?
Hey all, I'm about to start a job hunt after a few years as a postdoc doing biomedical computer vision. Academic/government research has been great and I've learned a lot but I'm getting frustrated with the slow pace and the disconnect between research incentives and solving tangible problems.

As part of my job search, I'd love to learn more about the landscape of startups applying or improving new computer vision tools to solving interesting problems. If I can get any direction here - either info on particular companies or general advice for how to find this stuff out on my own - it'd be really appreciated. Thanks!
It absolutely does; I've had civil conversations on Twitter many times, and I've been introduced to new information because of it. I've met people of similar beliefs, convictions and knowledge on Twitter. Ultimately, however, I left Twitter because of the problem pointed out by GP.
Now You Can Go to Bed in Sweden, Wake Up in London
This was a great read (and great nuggets, like that paper on Intelligence by Chollet).

I wonder:

— Is math a problem for non-academic researchers?

Most papers strike me as requiring a non-trivial knowledge of linear algebra, for instance; and topology sits right behind; the bold seem to take it one up on category theory as we speak, and geometric algebra is quickly gaining traction too. Lots of math, cool math but math nonetheless.

Not that you can't learn these on your own, but how big is the gap in practice, on the job, compared with actual PhDs in ML/math? (how much of a hinderance, a problem it is for the self-taught researcher)

— "Contracting" in the field of AI sounds great but, how exactly? Especially solo: what type of clients and how/where to find them, what type of 'business proposition' as a freelancer do you offer, what's the pricing structure of such gigs?

I mean, I can sell you websites and visuals and stuff, but AI? I know first-hand most SMBs (IME the only real customers for freelancers) are a tough sell: their datasets are tiny and demand scripting skills to sort out (extract business value), not AI, so the value proposition is low for both parties; it's still early adoption so 90% don't even consider spending 1 cent on "AI" unless as a SaaS (they actually don't need to know if it's AI or programming).

I can imagine tons of fantastic research to do with SMBs, as partners or 'interested sponsors' (should they reap benefits on a low investment), but really not much yet in the way of "freelancer products" to market and sell for a living. I'm eagerly anticipating those days, but it's more like 2025-2030 as I see it.

I would love to hear first hand takes on this.
Trust is earned. It's not something you can assume.

That "assumption of trust" you speak of included an assumption that either you weren't LGBT or you would bury it your entire life for the comfort of the larger community.

Matthew 10:34-36

34"Do not suppose that I have come to bring peace to the earth. I did not come to bring peace, but a sword. 35For I have come to turn "'a man against his father, a daughter against her mother, a daughter-in-law against her mother-in-law- 36a man's enemies will be the members of his own household.'

I would say you did the actual Christian thing by leaving. But I'm not Christian, so I'm sure many will find that assertion offensive.

Community cannot be founded upon an assumption that some people will bury an important part of themselves like that. That's a foundation of sand and will not last.

We are seeing such things dissolve because we have other options these days. In the past, people often grudgingly tolerated it because they had no place to go, not because being part of some larger community was some wonderfully fulfilling experience most of the time.

If the world is seeing a loss of identity, it is because we are being freed from the shackles of our old identity. It's normal for there to be a transition period where no one knows what's what.

That's not a problem. It's just a stage in a process.

It's only a problem if we get stuck here and fail to establish a new identity. Then the great experiment fails, the opportunity to become something better is lost and we likely see things crash and burn so the world can sort of return to it's old ways that kind of worked.
Why Sudden Acceleration in Tesla Cars Is Impossible
If police put out the clearest image possible, you still have to rely on those that know him to be willing to identify him. Friends of criminals aren't usually the type to turn each other in.
I really plan on people snapping out of it and realizing tracking of people in public places (including faces) really should be completely banned. It does nothing for the common good, it only helps advertisers and the government. It could be outlawed if there was enough demand for it. The world lived perfectly fine before it. Let China continue on down the road of madness, but surveillance is the opposite of freedom.
I had the same issue at some point. I now have autocomplete working on my pass with .zshrc

From memory I think autocomplete worked for pass once I started using antigen.

I have the following plugins in my .zshrc
plugins=(
zsh-syntax-highlighting
git
iterm2
dotenv
osx
zsh-autosuggestions
)

and also run antigen with user bundles for
zsh-autosuggestions
zsh-syntax-highlighting
zsh-completions

Some magic somewhere in the above provided autocomplete for me with pass.

I hope it helps.
The post is worded like they were in college at the time. College students can register to vote in either their home state or the state they attend school in, just not both.
Is it though? or is it the disenfranchised finally are able to have their opinion heard? We also get to see the emperors now and we realise they have no clothes - they're just like us.

My hope is this is a brief period of education of everyone to see each others opinions and something better can come of it. As always there are those at work trying to maintain their positions.

For myself I have learnt a lot about the belief systems of other people from the internet. I can only hope others are doing the same, we all have to get along.

Edit: I think of it as the great flattening, to coin a term, previous societies were hierarchical with people in charge handing down dogma. There were some dissenters - they were called antisocial at one stage. Now everyone is at the same level, I've had conversations on forums with people who invented tech, wrote books I've read, I could if I was so inclined seek out other fields - everything is open now. This is bound to cause some 'beefing'. End of beef.