skysight-inc/HackerNews huggingface dataset:
You can have instructions in your advanced directive about the conditions under which you want DNRs created on your behalf. (Even in the absence of advanced directives, a family members of a patient who cannot make decisions for themselves is often awarded medical power of attorney, in which case that family member can order a DNR for the patient. Needless to say, this is not ideal because the family member is often unsure exactly what the patient would want if they were of sound mind, and tend to err on the side of providing intensive care even with a bleak prognosis.)
That's optimistic of you to think that he's going to give more profits to the artist.
Well that was interesting until the attempt to turn "To just be grossly generalistic, you could put half of Trump's supporters into what I call the basket of deplorables."
and following regret over saying half, into "Hillary thought everyone who doesn't agree with her is a deplorable person."

I mean just, at least try?
You're advocating between drugs and the alternative you listed.

The problem is the alternative you've listed are usually for prevention not as a cure. At least all the papers I've seen are observational and retrospective. Drugs on the other hand are design experiment, clinical and casual.

You don't cure cancer with exercise and good diet.
Well at least it's not contagious so all they'll achieve is win a darwin award
OP here. This is correct.

RSS/Atom is alive and well, mainly because it's built into every CMS and blog engine by default, but requires some digging through the HEAD of a page to get it into a reader now that most browsers don't treat is as a first class format.
Circuit Notes: A Budget Function Generator
Here's a more informed article about Steve Jobs and cancer.

https://www.drmcdougall.com/misc/2011nl/nov/jobs.htm
That’s rarely performed on adults because the risks are so high. Even in children it’s a last resort reserved only for the most severe and morphine seizure cases.
Right now it's actually only about a third of the normal price.

It looks like John Carmack knew it was a gamble and wanted to write software to find out what the trick actually was.
One of the biggest issues right now, is that we have a community (doctors, scientist, researchers) who need to backup their claims with actual proof's or risk loosing their license/reputation vs a community of "gurus"/"self-healers" who don't have to backup any of their claims at all. Thus the "gurus" can make HUGE claims, that to someone sick sound much better than the conservative claims made by doctors.

Give both groups the same voice & reach, and guess who wins.
No, that's not the "fundamental problem". The fundamental problem is a type system that lies. A "pointer to string" is not actually a pointer to a string, it's a pointer to a string or to nothing. If your api returns a pointer of the latter type, it should signal this by making the return type "maybe-pointer to string" (although it has the same memory representation as "pointer to string"). Then, if the user tries to dereference a maybe-pointer (that is, to use a maybe-pointer as a pointer), the type system can statically catch this and make it a simple type check failure compilation error. The user must first check if it's null through a function that casts a maybe-pointer to a pointer.

Nothing about this precludes the usage of sentinel values.
Show HN: Custom Domains and TLS for Your OpenFaaS Functions
What if the reason haters are using the word "fraud" is not because of sour grape chewing about the random vagaries of chance, but because the company (at the behest of their leadership) has been lying to their customers about such things as:

1. Their employee list (not updating it quickly after major staffing changes)

2. Legal status: misrepresenting to the public and to customers that the company is licensed to operate in that capacity or is proceeding illegally?

3. Pressuring it's subscription customers to publish positive stories about the product and reportedly even threatening their access to it.

I ask because this article comes out days after a Business Insider article about a high profile YC company. Its author uses the words "fraud" on their twitter and "cult" in the article, and makes some of the accusations that I've listed above. It's difficult not to suspect the two events are linked.
Wow, turns out there's a lot of studies into e.g. paracetamol out there too. e.g. https://www.ncbi.nlm.nih.gov/pubmed/31523834

More here: https://twitter.com/autismepi/status/1214388671752916992/pho...
YouTube Playlist Duration Calculator
all this means is that musicians need to find a way to own their masters. You will never see Chance The Rapper sell his masters for the very reason this guy is buying up rights.
Uncorrelated probably means to the stock market. The US market was up about 30% in 2019, but I doubt the value of any particular Taylor Swift song increased by that much.

I’m sure there is some correlation to general GDP growth, and you would actually want that. It’s the specific stock market correlation that you tend to not want.
Okay? But that doesn’t make any sense because most assemblies (see: employment) of people don’t involve alcohol.
Chemists report a new use for the waste product of nuclear power generation
which is a weird quote to use, considering palpatine went on to rule for a couple more decades after the big fight.
The NSA's secret boxes in the now famous AT&T closet were well known long before Snowden
Have them ask their doctor about the NNT of statins (number needed to treat). Statins reduce cholesterol, and boy do they do a good job. But what are the outcomes? Despite the hypothesis, Lowered cholesterol does not really reduce your chances for a heart attack (NNT 217) or stroke (NNT > 300). Which means 217 have to take the drug for 3 years for 1 person to avoid a non fatal heart attack!

Most of those statin studies were done on men. There is growing evidence for women but for decades it was almost non existent.

One of the problems with the Pharmaceutical industry is how long term effects/safety data are never available until decades later, after the industry has heavily pushed the drug On doctors and patients and made a ton of money. I’m not saying it is necessarily nefarious, just that the incentives are misaligned for positive patient outcomes. All patients should be aware of that.
Yeah, this reminds me a lot of the "Impossibly Hungry Judges" problem[0].

[0] http://nautil.us/blog/impossibly-hungry-judges
Drinking can be an important part of relationships to the extent that we miss it deeply when it's gone.

This is a good read

https://www.nytimes.com/2012/08/19/fashion/a-glass-all-empty...
Regarding Expo specifically:
>>> I have to write bash scripts to create js files. This hurts my brain.
There is an issue on Expo's Github about env management https://github.com/expo/expo/issues/83

Now on a more general use case, I guess there are two types of applications:
- Client-side (like Expo): I would not store any "secret" for security purposes, just configuration. You seem to use JS for your client-side so use dotenv packages (https://www.npmjs.com/package/dotenv, https://www.npmjs.com/package/dotenv-webpack, etc...)

- Server-side: Depending on your environment, CI, hosting you might have a different solution, sadly not any one-fits-all solution to my knowledge. Heroku provides a pretty straight forward solution, on my production environment I use a configuration management, Chef's Data Bag but you could as well use a service discovery like Consul, Zookeeper, Etcd, etc...

I hope this is a bit helpful.
I understand your reasoning and appreciate you explaining the downvotes.
I still think it could be argued that GP’s comment could be better understood in terms of “what” rather than “how”. It’s easy for humans to interpret the outcome of the algorithmic pressure as punitive. And I would say is also understandable that is interpreted that way generally and specifically in GP context with that quote about leftovers.
As to the how, would it be possible NY hat humans/quants make algos that encode that believe?
Is writing/improving tools to fit your needs considered bad? If Google needed to store an exabyte of data into MySQL and they rewrote something with a MySQL compatible APIb (PingCap) would this have been bad?
> I still maintain that cocaine or meth would improve the driving skills and response times for a rested person.

Yeah, it does look like the evidence supports that. Interesting stuff.

If restedness is the real factor, it becomes pretty difficult to regulate that. There are two problems I can think of:

1. I don't think that someone being on meth or cocaine meets the burden of proof to say they aren't rested.

2. People drive without adequate rest, even without stimulants. If someone is hasn't slept in 48 hours, it seems like it would be better for them to be on stimulants than not.
> In fact I suspect that a sense of frustrated talent is what drives some people to become haters. They're not just saying "It's unfair that so-and-so is famous," but "It's unfair that so-and-so is famous, and not me."

> Could a hater be cured if they achieved something impressive? My guess is that it's a moot point, because they never will. I've been able to observe for long enough that I'm fairly confident the pattern works both ways: not only do people who do great work never become haters, haters never do great work.

Listening to that old Steve Jobs interview where he talks about Microsoft (https://www.youtube.com/watch?v=EJWWtV1w5fw) I think there elements there of what Paul would be calling a "hater". A view that there's something a bit wrong with the world when particular non-ideal characteristics are rewarded.

It sounds as if Paul has enough of his own personal issues with haters that he wants to put them all into an irredeemable bucket.
This is not the Bond villain we want.
Private communities promote bubbles where people become entrenched in their preconceived beliefs. Much like genetics, you need variety, and the strongest beliefs/traits will survive in the long run. I think a healthy mix of public and private communities is the “right” way forward. I will concede there is the ever present problem that toxic people are more likely to speak their mind, which leads to moderates thinking the extremes are the norm. Smaller communities might solve this problem, but I’m not sure moving to all private communities is a good thing. /2cents
The main thing I find amazing about the whole Telegram Gram debacle is the magnitude of money they were able to raise. $1.7 billion is just a ridiculous amount of money. Think about how much good that money could have produced if it were invested into useful companies and startups.
Yeah I blame the browser vendors, mainly Google and Mozilla. Enough resource to do shit like Webassembly, but apparently a XML format is too complex to integrate.
Judging by the downvotes I assume a few of the people from groups 1-5 are here. There are no scientifically founded reason be be against vaccines/nuclear/GMO, so grouping these things together by the parent comment should not be offensive to anyone
The key is to never apologize. As soon as you try to negotiate with the mobs or beg for forgiveness, they know they have you and your livelihood/job will soon be gone.

It's reminiscent of 1984, but Fahrenheit 451 also seems to be a blueprint for where are society is headed: It's not the government that creates a dystopian society, it's us.
An 18-carat gold nugget made of plastic
I think GP is merely suggesting that, if you are doing something truly subversive, it is best not to shout about it on a public internet forum.
Spot on. We have, all across the west (the situation in the UK is similar to the US) regulated medical professionals but not medical claims. This needs to be addressed, with a presumption in favour of malice where claims are clearly not approached properly.

We had a committee of parliamentarians conduct an inquiry into homeopathy back in 2010, and predictably they found (after consulting with experts, taking testimony from all quarters etc) it was bunk. To the best of my knowledge we have not altered either policy or legislation in response to that.
Thank you, if you try to make anything from that, we'll he a much healthier recorded music market.

A billion dollars seems a bit low though, no? Surely he's gonna miss a lot.
tosh and others do a lot of reposts, Wikipedia links, etc

karma farming?
I could also write my own novels and produce my own TV shows but they wouldn't be as good as what an Orwell or Sorkin could produce.
Care to link to the story?
What's the evidence that there is a brain or body in the first place, which is a big part of the original discussion? No, I don't mean that just because Plato said it cannot be "stupid", but you have clearly provoked the crowd bringing philosophy to the fore, and broadly speaking philosophy is where you stop having certain evidence for anything, as it precisely challenges anything deemed certain. Once the body is assumed and our senses trusted, if you find solid evidence it'll be about how the brain differs (or not) from the rest of the body, not about the presence or absence of a mind or soul.
> Still, a group of online cancer truthers have zeroed in on chemotherapy as the ultimate example of the hubris and greed of Western medicine and Big Pharma.

Anti-vaxxers and chemotherapy truthers are employ only somewhat more extreme forms of the fallacious mode of reasoning that dominates today’s media. Open up pretty much any article about a complex issue, and you’ll see the pattern. Relevant facts will be combined with irrelevant ones and set in a narrative arc, a story with clearly identified villains and victims. The reader knows what conclusions she is supposed to draw based on how she feels about the villains and victims, as opposed to objective big picture analysis.

Take a simple example: Trump’s recent proposed revisions to NEPA, the federal law that requires government entities to perform environmental review of infrastructure projects: https://www.nytimes.com/2020/01/09/climate/trump-nepa-enviro.... The whole thing is set within a narrative arc about Trump’s deregulatory agenda, with Trump as the villain. Isolated quotes from individuals are provided, making various assertions. Nowhere is there any analysis of objective facts by which someone could evaluate the proposal. For example, there is no mention of the fact that European countries have environmental review rules even more streamlined than what Trump is proposing. There is no mention of the median environmental review period of transit projects under NEPA (6.7 years), studies that have been done estimating the costs of delaying infrastructure projects (trillions), etc. Nothing to permit objective evaluation, just narrative, victims, and the villain. This is how journalists are taught to write and this is how they do write.

Anti-vaxxers and chemo truthers simply engage in a somewhat more extreme version of this reasoning. They likewise ignore the big picture analysis. Chemotherapy, for example, clearly causes harms, but has even greater benefits. There are many studies quantifying those harms relative to the benefits. Instead of looking at that analysis, they elevate the narrative above all else. “Big drug companies,” “western medicine,” etc., are the villains. The narrative is that those greedy players are suppressing natural remedies out of a desire for profit. Within that narrative, a few anecdotes about people getting better without cancer are all it takes to make the narrative plausible.

If you read Matt Taibbi’s work, for example, is he so different? He uses “Wall Street” and “big banks” in the same way as these folks use “western medicine.” He constructs a narrative where the entire global banking system, and practices employed by nearly every advanced democracy, are causing harm in the pursuit of profit. The experts are hoodwinking you, but he and a few others have seen through it! Throwing in a few anecdotes of misconduct or bad behavior seals the deal and makes the narrative believable.
I've noticed exactly the same experience in recent years with common colds (which I've had slightly more often than normal thanks to young children). Like the parent post, the day before I feel
"unusually well—almost high", and the next day the cold symptoms start, or I get a day of feeling especially unwell without any specific symptoms (the blearghs). Don't think I've read anything supporting this, but in my layperson's mind it is due to my immune system going into overdrive trying to fight the infection.
What's to say he's not trying to provide an innovative service? It'd be interesting to be at least able to license most pop music from one place, not that this is an ideal way to get there. If he prices pop music out of the culture, then less popular music becomes a viable alternative.
When Honey was acquired, I wondered why it was valued at $4B when all it does is apply coupon codes. Now it is clear - it's the data.

Look at https://www.joinhoney.com/ - they make no effort to tell you that they track / store all your order data across websites !
That's certainly a possible confounding factor that should be investigated, but let's not jump to conclusions.

Jumping to the conclusion that Monday surgeries are simpler could hide an important phenomena if that's not the reason Monday surgeries have lower 30 day mortality rates.
Well, if you are still doing what caused you to burn out, you won't be cured. If it's a job that won't stop the death march projects..you will need to quit.
"I don’t believe in material things."

Wants to own everything musical and starts up a billion dollar fund to do so.
That's a good number for a globally marketable product.

I read that Genoya for AIDS generated $4.8B USD in 2018 and Truvada, by the same company, Gilead, generated another $3B USD. So that's almost $8B per year and Truvada has a 3 year CAGR of 82% so it's really grabbing market share.

To your point there are other companies with competitive products but Gilead seems to be the leader.

My point is simply that one model, drugs at 8B per year, assumes a continuous disease state while the other at 5B per year assumes a continuous reduction in diseased hosts as was seen with Polio, Smallpox and until recently +measles for example.

One is better for the corporation. The other better for the commons. That's all I got.

+Measles was declared eradicated, in the USA, early in this century.
Yeah, I belong to the anti-nuclear faction. And grouping it with anti-vaxxers is just a cheap rhetorical shot. It’s not that Chernobyl or Fukushima or million of tons nuclear waste that someone else will have to pay for to take care of are products of imagination.
Resource Aware ML is a research language which analyzes resource usage, including memory bounds

http://raml.co/
A similar link in html, https://www.forwardcom.info/
No, I am obviously hiring Uber. I am going to the Uber app, putting a destination, looking at the price Uber quotes me, and clicking "go". In no meaningful way am I choosing my contractor myself.

Whether Uber chooses to structure the workforce as contractors or employees is their problem, not mine.
I thought of sports too. I personally have irrational hatred for rival players that, for example, accidental injured a player on my team in a big game. But it's almost like a joke or game; if I met the player in person I wouldn't act crazy.

I think the compartmentalizing you mentioned is interesting. In American politics right now, the home team and rivalry mentality seems to have spilled out into actually important areas of discourse. At the same time, neighbors still live in relative harmony in their day to day lives.

I just wonder if PG's theory really is more about trolls, despite him specifically addressing the distinction.
Steve Hall on LinkedIn: Firstpagegooglescreates FirstpageofGoogle #1onGooge
Do the things you do have to be world-class all-time greats in order to be worth doing?
How to build an OpenStack alternative: Step 1, the prototype
> I meant having a null per domain would force people to think of what it means to have nothing in that field and handle it.

In what way would it change anything? The "billion dollars mistake" is that because "nothing" is part of every type, any value you get could really be missing, and you have to either hope for the best (and die like the rest) or program ridiculously defensively.

Having a magical sentinel per type would have the exact same issue, namely that "nothing" is part of the type itself, and so you can never be sure at compile time that you do have "something".

That's what opt-in nullability (whether through option types or language builtins or a hybrid) changes, by default if you're told you have an A it can only be a valid A, and if you're told you might have an A you must either check for it or use "missing-safe" operations.
The interesting bit here is that literally everything you do or eat affects this.

For example your diet is going to get broken down into micronutrients and for a lot of these molecules, while they are circulating, there are a lot of receptors that they are going to bind to and modify function on.
And then there is exercise (or lack thereof) and all of the even-further away components (personal relationships, sleep etc) work on your brain and state of mind too.

When I was in Med school I came across this joke - apparently the effect size of antidepressants decreases with phase 3 trials, trending back to placebo. So the joke goes that as soon as a new antidepressant comes out, they need to use it before it stops working.

The deeper question here is whether the initial effect size was simply due to chance, and so the effect size of antidepressants is simply placebo and it was poor studies that let them get in the wild in the first place
You’re right, but I’m quite sure the “Asian world” doesn’t use that term, since homeopathy / allopathy / osteopathy are all western invented classifications.
Has he never heard of the Hunt Brothers and their attempt to corner the silver market? Supply & Demand dictates that prices can go higher than you are liquid.

https://en.wikipedia.org/wiki/Silver_Thursday
Journal 2020.1 – Clojure survey, core.async
You're correct about this but sadly getting downvoted. People have a hard time processing that their heroes very likely knew about Epstein's activities and at the very least looked the other way (some definitely participated themselves). Gates, Hawking, Groenig... all have their fans that will defend them to the death.

The evidence is there though for those that care to look. As you say, Epstein couldn't not talk about sex and young women, they were around constantly, everyone knew it was weird or they enjoyed the prospect of it.
That has nothing to do with it. The problem with the customer service is not them not honouring future discounts.

It was them not being good customer service, the general rule in customer service is basically try and do what ever the customer wants. In this case they wanted a coupon (probably for 10-20% off extremely expensive lamps) after buying a $2000 mattress. This doesn't matter and should have been given immediately.

The positive review of a single person is more important then losing 10-20% on a sale after a user already purchased another product.

Due to them not giving them a 10-20% coupon they lost a $2000 mattress sale and got a bad review on a site.
With a PhD in physics and against nuclear power I’m very happy to downvote anyone that groups that with anti-vaccines. I respect that people might have a different opinion than me about nuclear power, but calling opposing nuclear superstition is just cheap.
Stanford Lecture: Don Knuth – “Pi and the Art of Computer Programming”
On the contrary, in most European countries, due to anti terror regulations, you now need an ID to buy a SIM card or if you've bought one before this new law came into place you have to send a picture of your ID to the Telecom operator or your sim card gets deactivated.

Not saying I like this or that this is good way forward but it's a reality that contradicts your assumption.
Does Honey sell services to hedge funds?