skysight-inc/HackerNews huggingface dataset:
You can't argue with the "but what if" line of reasoning because there's always another hypothetical that could lead to the destruction of humanity or, at the very least, one more mutant baby than anticipated. And that's the problem here: these arguments boil down to "too dangerous", but that's not a characteristic amenable to empirically grounded, reasoned debate.

We can only have a scientifically constructive discussion within the context of a concrete, particularized therapy--disease, editing vector, gene, etc. Even then it's difficult, but at least you can reach a point at which you can agree to disagree on an actual, concrete scientific question. Everything else is philosophy and politics.

I think what people are trying to justify is an a priori assumption that gene editing (or germline editing if they're a little less cautious) is special and distinct. But I don't think you can scientifically justify that distinction from a harm avoidance perspective. Just because the technique is medically and scientifically distinguishable doesn't mean it's analytically distinguishable. And of course one of the principal drivers of these therapies, at least initially, is stopping the types of mutations that are feared but which already exist in nature.

So it's simply a belief that you hold; full stop. It's a legitimate belief, and may even be strongly informed by science, but it's like believing in God or aliens or the utility of Mars colonization--we might as well just put labels on our foreheads so we know where the argument will end up without actually having to argue. Knowing the other person's starting point, and assuming the best versions of their likely arguments, most of us here can arrive at the other person's conclusions independently.
I've been a team lead for close to four years now in two different companies, both times my teams spanned multiple time zones!

I really enjoy this subject and read a lot about it. My favorite books so far are:

- Radical Candor
-- Gives a great framework for candid conversations and empathy which IMO are the most important thing! Clear #1 in my list.

- Leading by Alex Ferguson
-- A great successful leader in another area - Soccer - that had many years building effective teams. It's incredible how many concepts can be mapped over, he talks for example on how having "rockstars" in a team that aren't team players isn't worth it.

- Ride of a lifetime by Bob Iger
-- It's mostly a biography of Disney's most successful CEO, I thought it was very authentic and gave good advices on how to deal with creative people, empathy, setting goals and navigating hard situations (compartmentalizing)

- Creativity Inc Amy / Ed
-- Pixar's president biography on how to manage creative teams, it is a bit repetitive but it is golden! Lots of good ideas and insightful chapters that make you think about how to build a successful culture.

- The Manager's Path: A Guide for Tech Leaders
-- IMO a bit shallow compared to the other books I mentioned but it was a pleasant read.
Suggestions are great. Whats better is just taking anything that people don't understand as "area for improvement". Then write it and see it it's better. Iterate. You'll learn your own style.
I'm not even convinced that would do it. They'll grandstand, and make a big fuss about it, and try to use the tragedy for personal gain, sure.

But at the end of the day, congress as a whole doesn't seem interested in fixing problems that affect actual people. They're only interested in making things easier for their corporate sponsors. They'll describe it as "we have to keep things in perspective" "don't want to stifle innovation" etc.
Now that we finally can run JS in AMP. That's been a big no since we can't run our normal funnel using AMP.
Something is clearly going wrong if the NSA thinks it's worth it to pay for $700/hr consultants from McKinsey. All the three-letter-agencies think Palantir is cutting edge, yet anecdotally, I hear that they're charging millions of dollars for some fancy charts and rudimentary data science.

Of course, there will always be some hyper-dedicated public servant types who are top of the line, and I'm sure that the director of the NSA is one of them. However, I doubt that the average rank and file senior engineer at the NSA is as competent their counterpart at Palantir because otherwise, they could just do all their work in house.
It doesn't have to take the form of an annual tax refund. It could take the form of lower, or negative, paycheck withholdings. The hard part is making sure that people don't end up owing a bunch of money at tax time, of course, because they're not going to have it lying around.
Why limit yourself to programmable semicolons? I hear C++ is going to have programmable whitespace: http://www.stroustrup.com/whitespace98.pdf
It'll be some time before I replace my current device, but once I do I'll be looking for something that supports LineageOS or Replicant although that'd still leave the hardware suspect.
WebAssembly Core 1.0 Is Now a W3C Recommendation
Are You Working on the Right Risks? (A Self-Assessment Tool for B2B Startups)
Veritas Genetics Suspends US Operations
Ah sorry I misunderstood
I think the idea is that you'll either use a screen reader or use the system zoom tool. Not defending it, but I can see the logic they used.
> Co-mingling is fine for books or, really, the vast majority of products. That in itself is not much of a problem... returns are free.

I couldn't disagree more.

One of the big reasons co-mingling works well for Amazon is because many counterfeit items aren't detected by consumers. But just because they aren't detected doesn't mean they don't do harm.

If I buy an Apple USB charger, I expect to get an Apple USB charger. I don't have the equipment to check it for loaded voltage sag (check out some videos of knock off USB chargers for examples). However fast it charges is however fast it charges, but I'm still being harmed by an inferior product.

If I buy a SpyderCo knife with expensive steel, that's what I expect to get. I don't have the equipment to determine whether something is AUS6 or S110V, so I'll probably just use it and sharpen it as needed. But just because I don't realize I've been sold a counterfeit doesn't mean that I haven't been harmed by an inferior product.
McDonalds franchise owners make 3x that. The average is dragged down by low rent chains like Subway or Wendy’s

Keep in mind that the owners make that after leasing the building from McDonalds. It’s a turnkey business and there are many, many people who have gotten pretty rich on operating these places.
I bike to work which takes me 30 minutes each way. I consider this as my relaxation, workout time and time to myself to think. Of course I also have podcasts running. Sometimes Audiobooks too but that requires more focus.
Background: When we started SKMurphy in 2003 we worked on a series of “startup maturity models” to help teams better understand where they were in their journey, which set of risks were the most appropriate areas of focus to make forward progress, and to help them identify missing achievements or capabilities that were the most likely to hold them back. This interactive version refines and extends earlier paper-and-pencil versions that we have used in talks, workshops, and consulting engagements for the last 16 years.
HTTP/2, HTTP/3, 5G, faster mobile phones, will all make AMP inconsequential and unnecessary, unless your primary audience lives in rural areas or are not able to adopt such technologies.

Applications used to fit on a floppy disk. Websites used to be a few K in size. AMP might be successful (if it's even considered successful), but only for a short while. I avoid AMP links when I can, since I don't want the jank, stripped down experience of a site. If I really want a great experience on publishing sites, I just turn on Reader Mode.

And of course, it's preposterous that Google gives preferences to AMP pages on search rankings. It's just as if Amazon prioritizes its own products in its search rankings (not saying it does or doesn't).
Lots of good recommendations here; two I would add are "Debugging Teams" and "The Geek Leader's Handbook"
The film Gattaca explores some of these themes.
3,000+ occurrences of sexual assault in the context of daily use of a so called civilized society’s modern features is a lot.

We’re not talking about babies dying of birth defects.

This is pointless numerical contextualizing which ignores humans are not machines. Does it make much logical sense to dismiss that we’ve evolved over thousands of years to take these emotional positions seriously?

Dismiss the problem plainly if that’s what your preference is. No need to box it up with your preferred style of equivocation. You could simply not post if your intent is to just nudge someone else to not care anyway.

“Pst hey I did some math. Nbd.” Duh.

Lookit me use numbers to show how dumb people are being.
How to ensure your brand stands out in a sea of sameness
Thanks for the info. We’re going to have to be deciding what to do with it in the next few years, and that’s an appealing option.
Most LeetCode questions like this are just riddles, especially at the moderate+ range. You either studied the question and know the answer or haven’t but could figure it out in a day or say, but not 45 minutes. And studying these questions have no value outside of acing interviews. But at least they know the interviewee cares enough to cram for the interview.
I worked for a mom and pop hot dog/Italian beef joint in the Chicago suburbs in the 90s and that’s exactly what it was. A totally un-PC Italian family that didn’t take any shit and insisted you didn’t take any shit either.

It was a blast.
I'd really appreciate more options like this - allowing you to spoof details.

At present, even though you have to approve permissions, I take it it's sufficiently rare for people to refuse them that app developers don't feel the need to rein themselves in, just based on the number of permissions still requested for very basic apps.

Allowing granular refusal was a step in the right direction, but plenty of apps still refuse to work unless granted permissions they don't need. Spoofing would be much better.
Reading location via GPS is passive with no outbound data transmission. As Apple explained, in line with the Apple engineer's prior response, there is a reason why this is not a privacy leak. It does not transmit the geo data off of the device at all. If they were transmitting it, people would see the data packets and want to know what it is.
I'm pretty sure there is no reasonable expectation of privacy while "walking down the street" anyway?
Pine64 December Update – First PinePhone Call and PineTime Dev Kits Available
Having started my career in this space, many years ago, I've grown to think there is not a good business model to be had. It's too bad, because there's a huge demand. These small companies wind up with bad solutions all around.
The initial comment upthread is wondering about how to serve non-technical people.

Most people could probably understand the technical stuff if they had enough spare time/interest, but if you don't have the technical literacy for it, "How to install on Ubuntu Bionic 18.04 x64" is confusing.

Whereas, "I followed these steps on this page (and the screenshots are how it looked like)" is easier.
I tried that at Amazon interview where the interviewer gave me the “Alien Dictionary” problem unmodified. Calling her out on it wasn’t wise, as I’m sure she torpedoed my chances while still doing decent on the rest of the loop.
This is beautiful, and horrifying. A cleverly written tale around some deep magic.

And yet.

Who among you would hire this witch? Who among you would want to maintain this kind of code, should this witch move on to challenges more suited to her skills?

Who among you would dare to meddle with the work of a Real Programmer[1]?

1: http://www.catb.org/jargon/html/story-of-mel.html
You can skip the "stream it back at night" part. If you have a big battery, you don't need to charge it to full every day. So you plug in day and night, and have an algorithm pick when it actually charges... based on the wind/sun forecast and your calendar entries.

Then there is no extra battery wear.

There are quite a few people here in Palo Alto who can plug in at work. Facebook has more than 100 chargers at their HQ, and half of the EVs at my apartment complex never use our free charger.
Pretty much all changes in minimum wages are small.

This makes it very hard to measure the effect with any precision. You have to remember that wages are not 100% of the compensation for employees. So if MW increases from $10 to $10:50, fringe benefits may be cut from $2 to $1:50, and you end up with no measurable effect.

> But the reality is that these shops need the workers regardless.

If their expenses become higher than their earnings, the shops will close. Maybe that at least is an economic fact we can agree on?
>supplements or baby food

These are the things I buy locally... well I did buy the Amazon Elements which I believe is an Amazon original... but I will probably go with Costco next.

I think there is probably a greater risk with chargers and fire. I remember Amazon banned the lithium balance things...
This has never been my understanding about the major ones, at least. The licenses are incredibly expensive to buy, but they are quite profitable. But I recognize we're both speaking totally vaguely and without sources, so I'm not sure why I'm replying when I have so little to add myself :)
This is a little too realistic...

You are a knight living in the kingdom of Larion. You have a steel longsword
and a wooden shield. You are on a quest to defeat the evil dragon of Larion.
You've heard he lives up at the north of the kingdom. You set on the path to
defeat him and walk into a dark forest. As you enter the forest you see a large
black dragon flying overhead. He is very angry and roaring.

> Kill dragon

The dragon lets out a roar that shakes the earth. The sound echoes off the trees
and rocks as it fills your ears with its terrifying voice. It calls upon all
his strength to fly towards you. You raise your sword and swing it down
> kiss dragon

You plunge your sword deep into the dragon's chest. Blood spurts from the wound
and you hear the dragon let out another roar. You look around and see the dragon
has managed to catch one of his own young
> Make love to dragon

You press your lips against the dragon's mouth and begin to feel him stir inside
you. He begins to move back and forth on top of you. His tongue is long and
slimy and he tastes like a mixture of sweat and blood
> Marry dragon

You pull away and laugh at the situation. "I don't think so". The dragon laughs
back and you both fall asleep.

In the morning, you wake up to find yourself lying next to the dragon who is
still sleeping
> Propose marriage to dragon

"Yes! Yes!" you say. "We should be married!"
The dragon smiles and nods. "Very well then".
You embrace each other and fall asleep.

A few days later, you awake to find the dragon gone
44M Microsoft users reused passwords in the first three months of 2019
The counterfeit products just use the logo marks and say they are legit even though they are not certified. It takes a savvy consumer to look them up.
Pantone Color of the Year 2020 (Classic Blue)
"accessory" (which the leaf technically has, but is hard to achieve without studying the manual).

I’ll remind our listeners at home that I’m the one with the eight year old Leaf. To this day, with a gun to my head, I couldn’t get it into “accessory” in under five minutes, if at all. From memory, it’s some combination of “this sequence” coupled with “but only if..., otherwise...”. If you master that, try and turn the heat on with it still plugged in, without using the app. It can be done, but...
Extreme alarmism is going to make the Internet an over-regulated hellscape that mostly benefits incumbents and further reinforces monopoly positions. We would all be worse off if something like what you’re describing was implemented.
For other options, there are various DWM1000-based boards out there. Check ebay, Ali Express, seed studio for examples.
The idea that these kind of jobs are meant for 'kids in high school' is a myth. The idea that the internet has leveled the playing field is perhaps not a myth, but wildly over-stated.

I hope that one day you find some empathy.
Dependent on who is searching it seems...
Ok.. mine got interesting from start...

You are Rod, a peasant living in the kingdom of Larion. You have a pitchfork and a nothing else. You wake up and begin working in the fields. You see a girl walking towards you. She is beautiful, but you can't help notice that she has no clothes on.

> Hello

"Hello".

The girl looks at you with her eyes wide open, as if she didn't expect such an answer.

"I'm sorry for waking you," says Rod. "What do you want?"

"My name's Anna," she says.

> What do you want?

"What do I want?"

"Anything".

Rod thinks about it for a moment. He sighs.

> Do you need clothes?

"No, no, I don't".

Anna nods. She then turns to you.

"Do you want some help?"

"Help?"

"Yeah, like how to use that thing on your head".

> My hat?

"Huh? No, not that", says Rod.

"Oh, okay".

She grabs your hand and pulls you towards the door.

"Come on, let's go back home".
> There's a rather irritating tendency to frankly insult the intelligence of anyone that's not working on $BIG_NAME_PACKAGE [...]

I apologize if what I said came across like that. I don't mean to insult the intelligence of people who want to roll their own build tooling, I just want to point out that doing so is a waste of time when somebody else has put in the work of building doing that for you. I would say the same thing to someone who wanted to build their own web framework instead of just using Rails/Django, or someone who wanted to build their own blog engine instead of using WordPress/Jekyll.

Your time is valuable. Don't waste it on writing Webpack configs.

Of course, if you're doing any of this to learn how things work, then more power to you! But if you're putting hand-rolled versions of popular frameworks and libraries in production, then you're doing a disservice to those who have to maintain those things after you've left your job.

I can say with confidence that most posters on HN (including myself) will do a worse job at setting up a build system than CRA. There are hundreds of contributors fixing issues in CRA, and all of them are really smart people. It's an open-source project with thousands of eyes looking at the code. I doubt that a lone developer working in a silo could come up with something better.
I'm baffled that no one has suggested that an individual is responsible for himself. Corporate health insurance, for instance, started due to wage & price controls. This shielded consumers from direct price increases. Instead of increasing wages, employers silently absorbed most of the costs, as evinced by the data [0] [1] [2].

Consumers almost certainly have more elastic purchasing preferences for insurance as a group, as they are much more granular. Insurance companies love negotiating with companies, because fewer, larger customers with greater inertia and specially-negotiated deals enable greater price discrimination than a mass-market product compared directly to others. This has further enabled the rise in prices.

I firmly believe that the individual is better-equipped to make his own decisions than any central planner or procurement department. We've messed things up enough with centralization; it's time to shift back to letting consumers make their own choices. Rather than taking even more choice by further centralizing from an oligopoly to a government monopoly, give people a chance to make their own decisions. I picked health insurance as it is a particularly hot topic, but this reasoning applies to many other areas.

[0]: https://fm-static.cnbc.com/awsmedia/chart/2019/8/19/image%20...

[1]: https://www.insurancejournal.com/news/national/2018/10/08/50...

[2]: https://www.insurancejournal.com/app/uploads/2018/10/2018-eh...
Well it happened. I had critically low phosphate which is the hallmark of refeeding syndrome.

And it’s not necessarily an absolute deficiency in electrolytes, it’s that when you break a fast with a carb rich meal, it drives the electrolytes into the cells so there is deficiency of electrolytes in the blood even if total body amount is normal.
So Elementary OS is essentially what Redhat Linux used to advertise itself as, but never quite was? A comprehensive, integrated desktop OS built on GNU/Linux?
From the cited article. So after investing $1-$3 million dollars, a McDonalds franchise owner makes about the same as a software engineer in a major US city and the software engineer didn’t have to spend $1 to $3 million and has a lot less risk.

Most franchise owners aren’t “starting a business” they are “buying a job”.

But a 2013 report from Franchise Business Review dug down into the numbers and came up with a net profit of $66,000 per franchise. McDonald's did much better with an average of around $150,000 per restaurant. But when you consider that a McDonald's franchise costs more than $1 million and can easily run more than $2 million, even McDonald's doesn't generate excellent average returns on investment. The fast-food franchise business is tough, and success doesn't come easy.
I’ve worked in the fast food industry for 14 years—about half my life

Can someone give me an anecdotal example of how this could come to be without some fault in Brown's decision-making process?

For starters, I've always heard that commute time is inversely proportional to career mobility. I made it a rule not to work anywhere farther than half an hour away. And that is the absolute maximum which was necessary when I lived rural area. Currently, I work remote, which has indeed provided more time for further career training.

My mother has worked at the same minimum-wage food joint for almost eight years. She tells me it's because she's "comfortable" and friends with everyone there. Personally, I think it affords her the time and lack of responsibility needed in order to engage in non-moderated drug use. This was certainly the reason she was usually unemployed and unable to provide the most basic resources for me as a child. If I bring up this or her other time-sucking addictions such as mobile gaming / simulated gambling, she becomes very defensive.

Regardless of the reason, comfort breeds complacency. Complacency leads to not making a meaningful change to your career trajectory in a 15-year period. As someone who grew up in relatively abject poverty, most of the positive things in my life have only come from within, due to my determination to succeed despite numerous setbacks. Sometimes I find myself having difficulty empathizing with people who seem reasonably intelligent but have been in the same situation for 10-20 years.
And then, after such a promising start... back to bad high school dating...

"Hey, you know what would be good right now?" asks Anna.

"Sure".

"A sandwich or something?".

"Yes, please".

"Okay, see ya later!"

And with those words, Anna leaves you alone
> Co-mingling is fine for books

Actually, its No Starch Press's counterfeit book examples that have served as proof for why Comingling is bad.

https://twitter.com/nostarch/status/1183095004258099202

At a minimum, it means that payment for counterfeit products go towards fake scammers instead of the actual publisher. You're basically paying for pirated goods.

Maybe you're fine with piracy, but paying good money for it is probably a step too far for most people. Especially if the pirated books have smudge-marks and low-quality paper.

> That in itself is not much of a problem... returns are free.

Are you able to tell the difference from a counterfeit book on bad paper and an official book? Are you going to blame Amazon for the fake, or are you going to blame the publisher?
No, she should get different assistance for her situation, or if not, then yes.
There is a port of windows already out and running on arm - MS even released a laptop running it ... https://www.microsoft.com/en-us/p/surface-pro-x/8vdnrp2m6hhc...