skysight-inc/HackerNews huggingface dataset:
This is also partly because more recent studies have determined that for important types of post-surgical pain of this sort, combination ibuprofen+acetaminophen is actually more effective than hydrocodone.

https://www.aafp.org/afp/2018/0301/p348.html

is one example, for patients presenting in the ER with extremity pain, and one that's specific to impacted wisdom tooth extraction is:

https://www.ncbi.nlm.nih.gov/pubmed/28586638

("CONCLUSION: Codeine 60 mg added to a regimen of paracetamol 1,000 mg and ibuprofen 400 mg does not improve analgesia after third molar surgery.")

There's a study I'm very curious to see the results of for this question for post-caesarian patients: https://clinicaltrials.gov/ct2/show/NCT03372382
(study is still underway).

And there's been really promising results for other forms of post-surgical pain management. One great example is the use of a QL nerve block administered during surgery to manage post-caesarian pain:

https://sci-hub.tw/https://rapm.bmj.com/content/early/2019/1...

"QL block has been associated with reduced postoperative opioid consumption and pain scores in patients undergoing cesarean delivery, [... but more study is needed because the studies weren't big/comprehensive enough ...]"

There are lots of caveats here (in other words, don't believe some random schmuck on the Internet over your doctor) -- different types of pain may respond differently, different people may respond differently, etc., etc. Ibuprofen impairs clotting and is inappropriate for use with some patients and some types of injury. Acetaminophen has to be dosed carefully to avoid liver toxicity. No free lunch. But it's certainly promising from the perspective of non-narcotic pain treatment _in some circumstances_.

(Please don't misconstrue what I'm saying, of course, as suggesting we can or should eliminate opiates. There's a place for everything in our arsenal. But there's been a lot of progress in the last decade that open up alternatives in some cases.)

Glossary, in case it's helpful: acetaminophen (US) = paracetamol (UK) = tylenol (brand name). ibuprofen = motrin = advil. oxycodone/acetaminophen = percoset (brand name; ratios may vary).
My wife is on an antiangiogenic and NSAIDs cause her nose to bleed pretty profusely for more or less the same reason. I always wonder why it's 'ok' for nosebleeds when there is likely to be similar vasculature all through the body, but the docs don't really get too wound up about it.
It's a fun thought exercise. I often wonder why Americans seem so set on having 50 states, so this was a useful basis to mock up a what-if scenario of fewer states.

E.g. if there were 10: https://imgur.com/a/gNvP9mC
Do you have a link? This sounds fascinating.
Law enforcement mostly uses lasers now. There are some detectors which pick up scattered laser light but they aren't very effective.
"For months now, journalists, industry insiders, and consumers have opined on who will “win” the streaming wars and why."

The more streaming services there will be, the more likely it is that only thepiratebay and torrents will win.
Most mestizos were illegitimate and did not enjoy the same rights as the Spanish under the casta system.
https://gist.github.com/chrispsn/da00835bb122c42f429a084df83...
I have the same problem in Japan. Certain times of the day DDG seems like it’ll never load and I normally switch to Google after about 4 or 5 seconds.
Fc.lc – Referral Link
And I’m not sure why you still think that EDA tools are so simple. I guess we’re at an impasse, then.

Going back to my first comment: I would be extremely impressed if China is able to build a home-grown, state-of-the-art EDA toolchain. I also still think that the US should work to protect its existing advantage in this area.
“Equity” lmao
Well, that's an interesting question. It would have been nearly impossible to make anything resembling a Big Mac in 1350, even if you were a king. And now you can get one for what, $4?

https://waldo.jaquith.org/blog/2011/12/impractical-cheesebur...
This is UK specific, so if the bank has a UK banking licence and it implements direct debit then they have to adhere to those laws and regulations.
> Additional services charges such as membership fees, villa-purchasing discount—yes, some exchanges offer deals on real estate!—and “pretty girl customer service,” which means personal service from an attractive rep.

Every time you think they can’t go any lower...
I think its amazing to think it wasn't so long ago you could actually disappear by simply keeping out of the spotlight. Now in most western countries there are few people who could pull this off, and would need to activity be masking your identity.
This is why I don't use neovim. VimScript is god awful (emacs lisp is also a pretty bad lisp imo), but this is just adding additional layers of complexity for no measurable gain in value. If I wanted to transpile to an equally bad scripting language and talk over RPC I'd just go become a front end developer (those web devs are out of control).
I just want vim to start quickly, not crash, and generally get out of my way. Vimscript is good enough for any sort of scripting/plugins I want/need and I know it's going to just work.
I’ve never been able to “deal with my thoughts” and also get sleep so since I was able to read I consume fiction before bed to wipe the mental slate clean. Before it was books, now mostly audiobooks or occasionally music so I can keep it dark for my wife. If I can’t do this its usually 1-3 hrs of brain processing worries from the day, next day etc. There must be others like me who can’t just turn off instantly.
PSA:
Use https://pubpeer.com/

and

https://retractionwatch.com/

There is also a browser plugin for pubpeer and a zotero plugin for retraction watch database:
https://chrome.google.com/webstore/detail/pubpeer/fmcdfigcdf...

https://www.zotero.org/blog/retracted-item-notifications/
There is, but since they're not able to sell your data they cost a lot. I bought a 55" LG OLED 1080p commercial signage display for $5000. The power and control hardware is in a separate box so the display panel is just 6 mm thick, and it has no "smart TV" features at all, just basic firmware for configuration.

https://www.lg.com/us/business/oled-displays/lg-55EJ5E
Yea I agree that most Chinese people in China have no problems in their day to day life. The problem is the principles of the CCP, the well-known methods of controlling population, the fascist aspects of the ruling almost 1.4 billion people.

Chinese people are just normal folks, middle class of China are busy with their lives as they are being lifted from poverty.

The problem is China’s government which does not allow criticism. No free press. Americans are taught to be respectful of all cultures - America is built upon immigration. So, please let me assure you that it’s not about the people, it’s about the political aspects of China.

- Do you think it’s okay to go around and suppress free speech in other countries?

- Do you think it’s okay to have 2 million people in concentration camps?

Instead of listing every thing, please read Drew Devaults blog here: https://drewdevault.com/2019/11/20/China.html

China’s CCP is using nationalism (which you’re obviously affected by) to tap into human psyche, gain unprecedented power and suppress democracy around the world.
Thanks!

My Pixel 4 charges at 18W, and I'm probably good as is.
> You've never heard of a slow-poke?

Sure, but that doesn't mean "slow slow". The poke part of that that means something similar to "yoke".

A slowpoke is something that's slow and dragging you down with it.
Already outshone by LED. We've got >80CRI 200+l/w LEDs (MK-R by Cree, been out for almost a decade) and 350l/w is already in the lab.

Even the pot growers shied away from this tech. The lacking red inhibited decent flowering. If you can't make an inroad there, you're almost guaranteed to fail.
I'm fine with a brick for heat dissipation, I just wish OEM bricks came with a label saying which device they're for.
Octagonal snowflakes are understandable since 8 is easy to make by folding and cutting paper and results in a symmetric design. I can kind of forgive that, especially if it's done as a crafting project.

What really confuses me is the 5-sided snowflakes. I really don't understand where that comes from, and there's pretty much no basis for it in nature other than starfish, which have practically no relation to crystalline structures.

I also get annoyed at restaurants that give children 4 crayons. I understand 3 (primary colors), 6 (primary and secondary colors), and _maybe_ 4 colors if one is black, but I see red, blue, green, and yellow quite often. What happened to orange and purple/violet? Is it really that much more expensive to make two more crayons? It's like they mashed RGB with the primary colors and called it a day. So if you're making a rainbow with 4 colors, I blame restaurants that give out 4 colors of crayons.
The problem with a popular repository can be that running the tests can take longer than the time you have between merges.

In GitLab we made merge trains https://docs.gitlab.com/ee/ci/merge_request_pipelines/pipeli... to solve this problem automatically.

With merge trains the merge requests with a passing feature branch is placed in a queue and tests are run against the combination of that branch and all the branches before it merged in. Since tests will pass 95%+ of the time the feature branches passes this can speed up the amount of merges you can get into master by 10x or more.
> You know, the whole publication + review + reproduction thing really helped science become a more solid process, but we need something more elaborate now.

No, we don’t. Increasing demands for rigour in pre-publication peer review are why publication times from submission sociology and economics reach and exceed two years and why papers which start off thirty pages long end up with eighty, after adding robustness checks and citing every tangentially relevant paper in the literature. We know that post publication peer review works perfectly well because it was the norm until after WWII with the rise of state funding of big science and the accompanying ass covering and form filling proceduralism that made it popular.

As always only replication counts, whether that’s checking that an experiment has the results claimed or that an argument follows from its premises.

We certainly don’t need to lean on reputation more. Science isn’t law; arguments from authority aren’t valid.
Silicon Valley is backwards in this regard. There's this mentality of always being busy; I can't help but feel it is a ruse for extroverts to flash their social proof at each other. In Silicon Valley, people always want to seem busier than they actually are, and people who are not busy are seen as inferior.

The next time someone asks if you're working on a side project, say "no". Carefully notice how their interest quickly turns into contempt. Similarly, people don't want to hear that you're "taking it easy" or "doing nothing" this weekend. That's literally all I tell people at work, and it just turns people off.
One of the very first things I thought of when I heard about WASM is, "Oh.. It would be so fun to build FORTH on that". I never got around to it (yet) and from a quick search, there are already a ton of implementations. But I think this is one of the things about FORTH: it's not just that you can run it on the metal. It's that you can easily build a FORTH environment for pretty much any metal you can think of. Bootstrapping from absolutely nothing to a very productive environment is really an empowering feeling. I always thought it was a shame that there are so many people who have made a Lisp, but so few that have made a FORTH. I kind of feel like both of these tasks should be required material in school... Though I only have nebulous feelings about why it is valuable... Not sure I could explain it to someone who hasn't done it already.
You can falsify your own argument by checking out the range of PD2 chargers from Anker or RavPower, observing the models with similar wattage and same multi voltages including up to 20V, and then noting the size differences.

They’re not making the new models bigger just for fun.
https://www.mashed.com/66838/secret-history-breakfast/

and
https://www.researchgate.net/publication/258276062_English_B...
Many Forth developers do not like using named parameters AKA local variables. That said, they certainly exist, so if that is your only objection to Forth then there are easy ways to solve it.

See, for example,

http://zedcode.blogspot.com/2011/02/forth-parameter-stack-na...
> There is something deeply toxic that has infected our community. I am still not quite able to see it in its entirety, though I can see its edges and when people get infected by it its obvious.

I think SlateStarCodex(!) said it well, recently:

> Rationalists wasted years worrying about various named biases, like the conjunction fallacy or the planning fallacy. But most of the problems we really care about aren’t any of those. They’re more like whatever makes the global warming skeptic fail to connect with all the evidence for global warming.

https://slatestarcodex.com/2019/11/26/mental-mountains/
I think I have read that that manufacturing employment has been falling in China and the world as a whole, too.
No, the real difference isn’t PD2. They have models with identical specs where size difference is not the PD but material.
That's not necessary legally, since the legal handover is already sufficient to justify non-intervention.

But of course the way Hong Kong was originally acquired at the point of a gun bolsters the moral/ethical case for both the legal handover and non-intervention.
Ugh. I ordered the four-port one they mentioned without considering it might not have UL approval. I'll be looking for the symbol when it comes now. Thanks for bringing it up.

If the thing works as advertised and is safe, it's amazingly useful. It should quickly charge absolutely every device I have except my work 2015 MacBook Pro (that I'll likely replace soon), and up to for of them at once. (Eg laptop, phone, battery pack, and wireless headphones simultaneously.) Handle US or EU input. And be very compact.
What's the point of comparing the number of disputes without at least normalizing for the size of the economy and the length of time being discussed? It looks unserious.
I'm really disappointed that PubPeer is used so little outside of bio/medical/social science fields. I'm not sure why this is. There seems to be essentially negligible interest in spotting mistakes in the literature in CS/physics/math/engineering (outside of materials science, just glacing at the site).

(For the record: I have posted a comment on PubPeer myself so I'm not a hypocrite.)
I think it depends on the distribution of content amongst the services. If it's a Pareto distribution where the top few services own the majority of the content, then I think people will pay for the top services. On the other hand, if the good content is highly fragmented amongst dozens of services, then the torrents will win.

It also depends on the business models. Right now, Netflix is "all or nothing" e.g. you can't pay 50 cents a month for a grab-bag of the content you want; you pay the full monthly subscription for all of the content. If every service was like this, and the content was highly fragmented, I don't see why people would overpay for content they don't even want.
A few years ago Toshiba was going to build a small reactor in Alaska. https://en.wikipedia.org/wiki/Galena_Nuclear_Power_Plant

But it got canceled, and for the life of me I can't understand why anyone thinks its better to truck in heavy fuel oil for generators vs having a small reactor buried in the ground for 30 years.

I've been saying for a few years now that green energy only advocates are basically on the side of coal and natural gas plants because they scream "green energy" and end up with a few MW of wind (ignoring the hydro built 50 years ago which to this day is still the majority "green energy" source) and a bunch of natural gas or in the past coal plants.

If they said yes to fission 40 years ago we wouldn't be having the climate crisis discussion today. We don't have 40 more years to overbuild wind/solar and perfect battery technology at 2-5x the current price for natural gas. Because if people don't start saying "yes" for carbon free power sources like this we _WILL_ be trying to figure out how to built them in 50 years to recapture all the carbon we burned into the atmosphere while trying to avoid more and more of the forests/etc from burning.
Times when someone doesn't have a realistic option to not be there are generally not great times to force conversation about anything controversial. Work, family get togethers, educational setting (unless it's covering such a topic) are examples.

Your lunch break out of the building, social time with friends, or other personal time occasions are great times to talk about whatever you like. Even get togethers or local debates if different opinions are what you're really itching to get exposed to.

And yes these are rules of thumb. There are certainly occasions it's both good and accepted to discuss it outside the above rules but they are just that - occasions. The article is referring to people who treat other people being stuck in the same room as them as prime opportunity to start discussing their opinions about last night's news daily.
> There's famous examples of revolutions in science being claimed as mundane results. Topologists said Nash was just applying topology to economics and it was nothing new (to them). Mathematicians saw Einstein's results as unsurprising because of the tensor analysis. (Some of these are over exaggerated and there's definitely a post hoc superiority complex in play).

Do you have any references for these examples?
> “We, and our many supporters worldwide, have done our best but the ignorance and laziness present in modern times have won.”

ok boomer.

In the UK the stray apostrophe was commonly called “the greengrocer’s apostrophe” as it could be commonly found in greengrocers on signs like “apple’s”. When was the last time you even saw a greengrocer? The term “greengrocer’s apostrophe” is so old that it pre-dates the massive rise of supermarkets. This is nothing to do with modern times, people didn’t care in the ’50s and they don’t care now.
The Air Force of the Knights Hospitaller
> I'd say that traveling or not, teaching people to torture other people should be a crime in any civilized society

Why do you feel that way? It's not against the law presently, as teaching is not a violent act and does not victimize anyone.
I would probably pay at least $50, in addition to whatever the services I use already cost me, for privacy and freedom from ads or any other manipulation I did not explicitly permit. Note I consider the latter at least as important as privacy.
Opioid use without a prescription includes the massive amount of oxycodone sold as a street drug, which helped to seed this crisis.

I knew of people buying oxycodone on the street a decade ago, and it was clear their dealers had a supply of name brand pills beyond "pills stolen from the medicine cabinet".
Stationary bike and tractors fit the mold perfectly; if you can't use it without the subscription, it's effectively a lease.

Food and printer ink are different because they are consumables.
And then, pot is legalized, and the marketing machine will be pushing that.

As I grow older, I've become way more conservative about legalizing drugs.
Aren't they also noisy AF? Wouldn't that affect power meters, or other measuring devices?
A nuclear reactor designed so small that can be placed in School Gyms. The phrase says all.

It seems that shootings at schools are not longer exciting enough for the three men in the photo. They could also place dynamite under the basement and a big red button in the main entrance with a "do not push" sign. Adolescents love a defy.
Tip of the Iceberg
It all depends on how much they end up costing to build compared to alternatives.
This would likely not work well in desert areas over an appreciable period of time, since most vanadium compounds are pretty soft, and desert winds tend to contain very hard particles of silica.
It took me a few minutes to set up CI for each of my smallish open source modules - and it caught problems with older Python versions quickly.

How am I doing it wrong?
RCS was a steaming pile of shit from the moment it was first announced. No instant messenger platform should be developed in this age without E2EE.

https://www.privacytools.io/software/real-time-communication...

I do think that Matrix really has the chance to stand out from the competitors here.

Particularly in regard to: https://www.privacytools.io/software/real-time-communication...
> We know that post publication peer review works perfectly well because it was the norm until after WWII with the rise of state funding of big science and the accompanying ass covering and form filling proceduralism that made it popular.

You know if there's anything written about the history of the modern scientific process, specifically on the rise of state funding of science? I'm particularly interested in when academics started to be essentially required to bring in external funding. I've only read offhand remarks like this and don't feel I have the full story.
Does anybody know how the scoring system works for AoC?
A few years ago, I got annoyed with a Google phone (Nexus something I think) that broke, given how expensive it was, and replaced it with a Motorola Android phone that was well under $100. I didn't really sacrifice the basic necessities - sure, the screen was small and side by side with a high end phone obviously less bright and lower resolution, but providing you didn't care about processor intensive apps/games, it served the same purpose.

Edit:
Of course, I am assuming there wasn't a substantial subsidy from somewhere, but from my point of view, it didn't have a contract attached.
i just copy/pasted the data into the source instead of dealing with IO.
The act of figuring out how to solve the problem is itself an act of trial and error. And in many problems, the clever part is figuring out how to target your trial and error.

For instance, if you want to find the global minimum of some function on the integers, you might realize you can find the roots of the derivative and test only the neighboring integers. If you want to divide 144359305 by 241, you're going to start by guessing how many times 241 goes into 1443, and then multiply to check whether that's right. If you want to compute floor(29489238428^(1/3)) by hand, you're better off smartly guessing and checking than trying to figure out a digit-by-digit cube root algorithm on the spot.
Google does seem to have their 'recency bias' setting set to 11. If any of your search terms have been in the news in the last 2 weeks, those articles are all you are going to get.
Wow, they managed to build a Google competitor that doesn't suck. This is actually pretty crazy. I never thought there would be new innovation in the search space. I'll be using this from now on.
I know of languages that can automatically convert some kinds of recursive code into the iterative equivalent automatically, but I've never seen one that can make the recursive version faster than an iterative equivalent.
The saddest double-standard of all that’s driven by pure stupidity is the phenomenon of “environmental activists” who decry efforts to develop and deploy nuclear power.

We could’ve been carbon neutral, but the green morons had to make a scene and screech “wind and solar” playing into their fictitious enemies hand (coal, natural gas etc.)
Wow, one in 10 people prescribed opioids become addicted? I wouldn't like those odds.