skysight-inc/HackerNews huggingface dataset:
It's difficult. The standard way in frogs is to just keep injecting them until the altered cells outnumber the regular ones. You wouldn't have to change them all though, often genetic diseases are confined to a particular tissue.

There are also theories around using a live virus to carry the genetic material, theoretically a virus like that could leave behind the desired mutation as it replicates through the body's cells. Promising mechanism, though I don't know of anyone who's pulled it off.
I think we can only really do 1 of them, temperature.

Pressures are no-where near the core of the sun (300 billion bar), nor are confinement times (years).

Which is why we use D-T fusion, which is not at all the same as the "clean, natural hydrogen fusion" in the sun. That whole "clean energy, like the sun" argument is fake.
Even massive, pervasive investment in renewables just isn’t enough. This is why a lot of prominent environmentalists have started supporting Nuclear.
I'm sorry but that's ridiculous. The sun uses a different fusion reaction. There is plenty of evidence that with other fuels, net power from fusion is feasible on Earth.

In particular, the D-T reaction is especially easy, and tokamaks have well-known scaling laws. The JET reactor in the UK is the only reactor using tritium and has produced 67% of its input power. In 1999 the JT-60 in Japan achieved results with D-D fuel that would have hit breakeven with D-T.

With a larger reactor, stronger magnetic fields, and D-T fuel, net power is the expected result.

(Not to mention, we've already achieved net power at human scales with thermonuclear bombs, which have far more energy density than a dung hill.)
Yes, we all know and love Java cross-platform UIs.
Yeah, but no. Air conditioning and refrigeration produce localised cooling, but an overall heating effect thanks to inefficiencies. Worldwide air conditioning would dump even more waste heat into the atmosphere. Just as trying to cool the kitchen by leaving the freezer door open warms it, trying to cool the atmosphere with worldwide air conditioning will warm it even more.
I have used Boostnote and Remarkable, on Ubuntu. After using Boostnote for a while, it started to bug me because it's slow load time (it's an Electron app), so I searched for something native and found Remarkable, which is simple and really fast. It just lacks some of the organization features that Boostnote offers.
I was just exploring how effective iPad Pro would be for pushing code while traveling. This looks super interesting.
It's part of the ITER project, which will receive 20 billion euros over the project's lifetime from participating nations.
Burning fuel isn't the only process of modern society that produces heat as a by-product. Lighting (though we're massively more efficient these days) and circuitry (computers and other electronic gadgets) for example. Then you have people running central heating more frequently as energy costs come down or people building less energy efficient housing because it becomes less important to people. I'm sure there are more examples I've not thought of too.

Disclaimer: I also don't agree with the GP's position
Container ships can run on hydrogen
Airbnb Loses Jersey City Home-Share War by a Landslide
Maybe, but this study is about GPs who worked exclusively in the private sector (the NHS just subsidized the prescriptions), not about NHS doctors.
Some work has been done in this direction! https://arxiv.org/abs/1905.12616
I think it's one of the best, because it's also the most efficient way to write GUIs on Windows. Definitely not overengineered.

MFC is horrible, I agree. I've had to work with it and the indirection just gets in the way and creates bloat. That is overengineering.
I'm going to defer to Taleb on this one and say that the biggest risk is the one we're currently unaware of.
was going to make a similar comment but mention that i can see this as an advantage over google and amazon clouds. they can just offer a solid editor with their offering now, making it easier to develop on their cloud.
I have to wonder about this fear. Essentially we are claiming that a highly motivated and technically proficient person or group of persons will seek to eliminate an ethnic group. There are many prerequisites to carry this out, including obtaining comprehensive genomic profiles of the group, as well as genomic profiles of closely related groups which you don't want to target, obtaining tissue samples from the group, designing a vector... I'll stop there, but to actually create an ethnicity specific disease is very difficult, and probably limited to large groups of scientists with significant funding. This assumes you want to be more specific than say killing all Asians, or Northern Europeans, which would be easier.

I think drones with facial recognition would be dramatically easier and more feasible... I mean, someone could actually do this next week.
Or fit heat pumps instead of gas boilers. The cost difference isn't that much and would come much lower if they were sold in greater numbers.
I'm a Democrat and Trump Rules
Hi I'm registered as a Democrat and I don't like any of his policies but people said stuff and I wasn't listening before but I am now and now I know those people are hacks and now I will vote for trump because this needs to end

How do we end it? My cousin told me about Go. He's a libertarian. Can we program a bot in Go to do this? Would python be better? We just really need to protect him if anybody doesn't know

I just want to let you know I'm respected in my field so serious replies only please
Building a conventional fission plant can easily cost $10B: https://thebulletin.org/2019/06/why-nuclear-power-plants-cos...

$200M is laughable - as is the 20 year plan. I recently reread Summa Technologicae by Stanislaw Lem. Written in 1961, it also guessed that fusion will be there 20 years in the future - meaning 1981 :)
Admittedly, I'm a bit of a special case: I have a chronic condition since my teenage years, but it was only diagnosed recently. And the decision of the army did appear with the bill. But usually, most people don't try to get in the swiss army, but rather out. The military service is not exactly popular among the young generation, and a lot of people would prefer to do an alternative service (civilian service or civil protection) to avoid the military tax. A trend in politics is to make those alternatives as unattractive as possible (from an economic perspective, or the number of days you have to servce). The army seems to have difficulties to fill their ranks (or so they claim, at least). As far as my experience goes, there aren't picky on the medical part during the recruitment. Trying to cheat the medical experts with all kind of stuff (claiming to do drugs, to be suicidal, ...) is a common way to try to avoid the military service.

A reason I'm so bitter about it is the fact that, while my condition _did_ seriously affect me during the recruit school from a physical point of view (long walks and stuff like that, but it was still undiagnosed, and the military medics at the time simply judged that I was a "simulator"), using it as a pretext to have me pay the tax now, when my militaries duties are hardly more than office work, after I struggled so much to actually overcome my disease and complete the hard part, feels... unfair.

It's noteworthy that Switzerland was called out by the ECHR (European Court of Human Rights) on the matter, judging it discriminatory[0]. Following that, a system to allow people with disabilities to candidate for the army service has been introduced[1]. I'm currently trying to be reintegrated. However, they still reserve the rights to refuse anyone for any reason. So, I guess I will see if it's real, or just a mock to please the ECHR.

[0] https://www.escr-net.org/caselaw/2012/glor-v-switzerland
[1] https://www.estv.admin.ch/estv/de/home/direkte-bundessteuer/...
Previous discussion, including a Q&A with the VS Online PM: https://news.ycombinator.com/item?id=21442088
The Humanoid Stain – Art Lessons from Our Cave-Dwelling Ancestors
I don't program in python but I'm interested to know how the process of finding a co-host and starting your podcast goes. Do you plan to blog about it? If you are new to podcasting in general I'm also curious to read about your learning about audio and production, which app(s) you use and why, where you host your podcast and why, etc.
This entire page is broken on Firefox 70.
... will evaporate faster than they can accumulate.
I was not aware of this at all. How did Backcountry get the trademark in the first place? It should definitely fail on the first challenge if backcountry is literally a subtype of ski and pre-existed. I know nothing about skis, and all the comments here and in the article made it sound like the furor was all over the generic adjective of 'backcountry' which I took to just be a synonym for 'rustic'.
There is a second problem in cold places that comes from the humidity you add on the air intake. The heat exchanger has to deal with that moisture freezing on the exhaust side. There are methods for doing this but none of them are ideal.
If you're making general statements about animals, then they should also apply to a set of camels.
The new Austrian embassy in Jakarta is Passivhaus certified, a first for that climate.

http://www.passivhaustrust.org.uk/news/detail/?nId=527
The more interesting thing is github integration. Will this provide a more pleasant way to browse repositories online without having to clone locally?
Tools for faster back end development BaaS
Win32 was complicated. Lots of cleanup work. No forced structure. Combine that with having to use C, and the amount of low-skilled porogrammers out there, you could really see why there was so much terrible Windows software out there.

Learning Windows programming gave me so much insight to programs crashing and all the graphical bugs, beause I had caused them all in my own porograms before.
I wanted to try this as the possibilities could be quite cool but got discouraged after seeing it is a monthly service. Tired of everything turning into a service that you pay for. Rather just carry my laptop.
It doesn't look like a 1024x800 display either ;)

Our code standard has a 150 character max line length, with the formatter trying for 120. That's working out quite well for us.
Also you can add the unions propping up outdated industries like coal mining
Hopefully its implementation is browser and OS agnostic on the client. I've had difficulty using Office 365 and OneDrive web access on Linux, which means I can't even consider using those services in a professional workflow.
DNA database that found Golden State Killer is potential national security leak
Compared to nothing on those who try to fill the void? Hell yes. Look at those raised in literal cults for example or among fundamentalists. Now I know these are tripping hazards for ants low goal posts but for once "it could be worse" is pertinent. An education can provide the prerequisites to evaluate and enable it.

Often they do try to put their bullshit in it but their hamhandedness in practice often backfires by adolescence - especially with their own twisted priorities and misrule related discontent.
Maybe this: https://github.com/tcr/edit-text

But yeah, most browser based WYSIWYG editors are JS based, since you need to manipulate the DOM.

If you are not targeting the browser then you maybe find something here:

https://philippegroarke.com/posts/2018/c++_ui_solutions/
Flavors of E-Cigarettes Used by Youths in the United States
C programmers who want to dig deep into the language and its capabilities
what's a better alternative, assuming you need to encode binary data in a text stream?
Thank you for being transparent that this is just a product page so far, don't enjoy getting bait and switched to provide an email. With regards to the product, I like the idea of reusable blocks.
First of all, the exactly same reasoning was used after the horrors of WWI, when everyone believed another European war will never be repeated, with known results on the readiness of the Swiss Army at the beginning of WWII.

Second, conflicts are on a gradient, from scattered terrorist attacks to a full on military invasion, there is a lot in between.

The statement that there is no conceivable threat scenario is ridiculous.
Couldn't Google and Amazon just do the same?
Difference is that Muyembe sent blood samples to man who later had credit for discovery and acknowledges what happened:

> The man who gets the bulk of the credit for discovering Ebola is Dr. Peter Piot. At the time, he was a young microbiologist at the Institute for Tropical Medicine in Belgium. He was the one to receive the blood samples sent by Muyembe. [...] When asked if he feels responsible for writing Muyembe out of history, Piot pauses. "I think that's a fair comment," he says. [...] Piot says at the time of that first Ebola outbreak, African scientists were simply excluded. White scientists — with a colonial mentality — parachuted in, took samples, wrote papers that were published in the West and took all of the credit.
Seems like there'd be a market opportunity to automate or at least create an assembly line for constructing the most at-risk parts of buildings. Or to make systems which might cost more in materials but assemble correctly with low skilled labor quickly.

I'm sure there's lots of this already going on. New houses built recently near me have all the walls delivered on a truck preassembled, but the skill and quality of the assembly teams from house to house has been interesting to watch from afar.
go read r/wallstreetbets
Was not the problem with MAX in part due to Boeing trying to milk the old design?
It's possible to find out whether a 787 was made in Everett or Charleston by checking the production site and remarks on planespotters.net

e.g. https://www.planespotters.net/airframe/Boeing/787/G-ZBJM-Bri... vs. https://www.planespotters.net/airframe/Boeing/787/9V-SCF-Sin...
I've heard it said that journalism is never objective, and nor does it strive to be. However, responsible journalism is aware of its biases and reports in a manner that allows audiences to weigh the facts themselves.
> Negative resistance devices are very tricky to use

Sure...

I'm not an engineer, but I read that tunnel diodes were hailed as the greatest innovation in semiconductor of the 1960s, and it was often the only available option in high-frequency applications, but they were almost completely abandoned when integrated circuits became feasible. Leaving the embarrassing situation that the tunnel diodes in lot of vintage Tektronix oscilloscopes are unobtainium.

> Bell created a design that was commercially useful and widely applicable

This is kind of the point made by the original comment. Arguing about the "first" sometimes is a waste of time, it's better to list all the codiscoverers and discuss their respective contributions.
Building one of the most popular crypto platforms
You can actually spin up your own web-based VSCode using https://github.com/cdr/code-server.
You’re not wrong. I would think, based off of my observations of bart, that handing pg and e to the government can only at best create an entity similar to bart. Since you say it’s already similar, there’s really no point.
lol @ you being downvoted for even asking. Shows how much of a leftist website this is: someone who goes against big corporations must be right!
How many Commodore 64 computers were sold? (2011)
iOS 13 allows the Shortcuts app to encode/decode information as Base64 as part of the scripting language.

People are using this to do clever things like encoding a watermark image to overlay on a picture, because the Shortcuts app does not allow file attachments as part of the scripting language.
History is full of examples of over priced bubble assets that have eventually collapsed.

So I don't think the questions is will it collapse but instead when will it collapse?
Amazon already has a competitor, Cloud 9. I’ve been constantly surprised that Amazon and Red Hat have cloud IDEs but Microsoft didn’t.
Those articles seem overblown. Providing access to UWP APIs from regular desktop apps will, if anything, increase the number of applications using those APIs. UWP GUI APIs could be especially attractive option to those applications currently using win32 forms.
Here in NL the two are also usually inseparable (you buy a house from a large project, typically 100+ homes/apartments, sometimes even 1000+). But, just looking around our two countries, it just seems requirements in the UK must be lower. The average house just seems less well built.
I want to like this, but having no support for Firefox, no SLA during the preview[1] & being unable to figure out the pricing model[2] makes that very difficult.

[1] How safe are my projects and what guarantees do I get that my work won't be lost?

[2] For cloud-hosted environments, each environment instance is billed based on the number of consumed “environment units”, which are calculated according to an environment’s instance size, the total time the environment is active (i.e. a user is connected to it via the browser-based editor or via a client such as Visual Studio Code) and the total lifetime of the environment (base units).
It's a cloud dev environment running in a VM (which you provision). It can work directly in the browser using the VS Code shell or you can connect to it with your locally running VS Code or Visual Studio.
WeWork investor Softbank: My judgment was not right
I think if you graphed environmentalist support of nuclear, you'd see it rise and then fall as renewables performed better and better. 10 years ago it made some kind of sense to cover our bets but renewables and storage have got so much better, while fusion continues to drag on and fission continues to have cost issues that I'm not aware of many prominent environmentalists that are still on board with it in anything other than a small complementary role to renewables.

I do regularly see articles from that one nuclear proponent who tries to get Street cred by claiming to be an environmentalist while attacking basically all other environmentalists as communists that want to return to the stone age and competing renewables as a hoax/environmental disaster/communist plot. But he seems a bit extreme.
No, storing cookies needed to make your site work was always needed.

Sending tracking information to third parties required a notice of some kind, no matter if it was in the form of cookies or some other mechanism.

So, no there was never a EU cookie law, it was just a major FUD operation and a lot of people put up completely unneccessary cookie consent popups without understanding why.
There has already been reporting on people leaving ladders and other tools inside delivered 787s. I'm not sure what Boeing is good at anymore besides gaming regulatory systems.
Embrace. (2017 - Visual Studio Code)
Extend. (2019 - Visual Studio Online, GitHub, Azure DevOps)
Extinguish. (???)
that actually sounds like a good idea for a blog post :)
How can one value something fat-tailed?
Launching Selgora.com – Marketing Automations
That’s how it works in NL; the power grid is owned by a separate entity (I think a consortium, not sure whether regional or national.) The cable and fiber networks are also separate and - lo! Behold! - the water management company board is even an elected body!

And NL is the least “socialist” place I’ve even known
Altohugh I am not particularly upset about it, South African scientists have often not gotten recognition and even the white males ones! [1] [2] I think the discrimination is worse in a way than described in the article. But maybe that touches even on the philosophy of individual recognition itself.

[1] https://en.wikipedia.org/wiki/Christiaan_Barnard#First_human.... I've been told that in particular, the USA was not keen of giving someone outside of the US recognition for the first heart transplant. And somewhat ironically, Chris Barnard's brother that was part of the team, Marius, did not get recognition (but that may have been due to his less extravagant personality). https://en.wikipedia.org/wiki/Marius_Barnard_(surgeon)

[2] https://en.wikipedia.org/wiki/Penis_transplant From what I understand, the US was again hesitant to cede to South Africa, instead stressing the first "penis and scrotum" transplant.
Where this gets interesting is where this and projects like Eclipse Che [1] are self-hosted in companies that have or want to have dev workflow where the source code doesn't leave a locked environment (no source allowed on dev's machine). (Companies that require you to ssh or rdp to a remote dev environment on some tightly controlled-sub-net.) Naturally, something like this would need to be host-able on-prem, but it's cool to see advancements in web-based code editing.

[1] https://www.eclipse.org/che/
1. Decode to bytes.

2. Do whatever you said.
Flavorists are trying to make plant-based meat taste like the real thing
I’ve heard the argument that it’s a matter of money rather than time. The physics is such that a big device is a good choice. Even the compact designs based on high field HTS coils will need to overcome their high power density in the divertor, that hasn’t come up much yet but it will. So we want a big device to figure out divertors and breeding and managing instabilities. Great. We’ll a just make the one, ITER. Well we’re still waiting. If someone with a lot of money wanted it to happen Right Now they could. You just need a 40 billion dollar c(r)ash program.
The population of Europe is already declining and other continents are likely to follow as their standard of living increases. Average fertiliy across the world has been in decline for about 50 years now and has halved over this period [1]. If the trend continues we will simply run out of people and go extinct.

https://ourworldindata.org/fertility-rate
That's the old microsoft and was used against competitors. Why would they extinguish their own products here and what would they gain from it?
If I'm not mistaken that's how most of the actor model frameworks are supposed to work. An example is Akka. The developer writes code communicating between actors using an interface that abstracts how they are actually communicating.
I love web-based IDEs but I haven’t found one that works with an iPad yet. AWS Cloud 9 kind of worked up until iOS 13 but now it complains about third party cookies and refuses to let me in. Before iOS 13 it worked but the keyboard had a lot of problems.

Should be possible, but in my experience it’s just not right now.
"Student loan debt “becomes a question of access, and not everyone, especially minorities, have connections in the entertainment industries,” says a Latinx production coordinator for a major animation studio."

What's a Latinx production coordinator?
Unfortunately just using less energy will not happen by asking nicely, and as most do not want that, it will not happen. Instead we should focus on the things that are achievable, like increasing efficiency.

>fusion is not ideal.
Why does it have to be ideal? It should be sufficient. Anything is better than burning coal.
LOL @ "Multi-modal". The whole point of "modal" is that it introduces a new [mode](https://en.wikipedia.org/wiki/Mode_(user_interface)) in which the interactions that were possible a moment ago cease to be possible, until you've dealt with the modal and leave that mode, returning to your prior mode. "Multi-modal" is just "windows".
> Reading this feels

I don't disbelieve you, but I suggest you try reading it again with an open mind. I think you are unconsciously imposing a stereotype onto those lines.